David Proud

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David Proud is affiliated with the following schools: University of Calgary, University of California, Berkeley, Stanford University, Johns Hopkins University

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David Proud

Computer Science

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#5942

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Machine Learning

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#1586

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Artificial Intelligence

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#1828

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#2769

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#2893

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Computer Science

David Proud's Degrees

PhD Computer Science Stanford University
Masters Artificial Intelligence University of California, Berkeley

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David Proud's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Inflammatory mediators in late antigen-induced rhinitis. (1985) (715)
British Thoracic Society guideline on pulmonary rehabilitation in adults: accredited by NICE (2013) (520)
Infection of a human respiratory epithelial cell line with rhinovirus. Induction of cytokine release and modulation of susceptibility to infection by cytokine exposure. (1995) (410)
Kinin formation: mechanisms and role in inflammatory disorders. (1988) (391)
Immediate and late inflammatory responses to ragweed antigen challenge of the peripheral airways in allergic asthmatics. Cellular, mediator, and permeability changes. (1991) (366)
Kinins are generated in vivo following nasal airway challenge of allergic individuals with allergen. (1983) (323)
Human airway epithelial cells produce IP-10 (CXCL10) in vitro and in vivo upon rhinovirus infection. (2005) (276)
Expression of the chemokine RANTES by a human bronchial epithelial cell line. Modulation by cytokines and glucocorticoids. (1995) (274)
Kinins are generated during experimental rhinovirus colds. (1988) (273)
Detection of tissue kallikrein in the bronchoalveolar lavage fluid of asthmatic subjects. (1987) (259)
Evidence for elevated levels of histamine, prostaglandin D2, and other bronchoconstricting prostaglandins in the airways of subjects with mild asthma. (1990) (257)
Inhibition of mediator release in allergic rhinitis by pretreatment with topical glucocorticosteroids. (1987) (254)
Mutation in the gene responsible for cystic fibrosis and predisposition to chronic rhinosinusitis in the general population. (2000) (251)
Nasal challenge with cold, dry air results in release of inflammatory mediators. Possible mast cell involvement. (1985) (245)
Epithelia cells as regulators of airway inflammation. (1998) (244)
Cyclooxygenase metabolism of endogenous arachidonic acid by cultured human tracheal epithelial cells. (1989) (207)
Nasal provocation with bradykinin induces symptoms of rhinitis and a sore throat. (1988) (205)
Nitric Oxide Inhibits Rhinovirus-Induced Cytokine Production and Viral Replication in a Human Respiratory Epithelial Cell Line (1998) (205)
Nasal challenge with ragweed pollen in hay fever patients. Effect of immunotherapy. (1985) (203)
Epithelial cells and airway diseases (2011) (197)
Studies of IgE-dependent histamine releasing factors: heterogeneity of IgE. (1987) (178)
Elevation of tissue kallikrein and kinin in the airways of asthmatic subjects after endobronchial allergen challenge. (1992) (168)
Nerve growth factor expression and release in allergic inflammatory disease of the upper airways. (2000) (167)
Gene expression profiles during in vivo human rhinovirus infection: insights into the host response. (2008) (163)
Inflammatory mediator release on conjunctival provocation of allergic subjects with allergen. (1990) (158)
Human Rhinovirus Infection Induces Airway Epithelial Cell Production of Human β-Defensin 2 Both In Vitro and In Vivo1 (2004) (158)
Immunotherapy decreases antigen-induced eosinophil cell migration into the nasal cavity. (1991) (157)
Effect of short-term systemic glucocorticoid treatment on human nasal mediator release after antigen challenge. (1987) (156)
Increased levels of interleukin-1 are detected in nasal secretions of volunteers during experimental rhinovirus colds. (1994) (150)
Effects of immunotherapy on the early, late, and rechallenge nasal reaction to provocation with allergen: changes in inflammatory mediators and cells. (1991) (147)
Identification and Partial Characterization (1986) (136)
Effect of ozone inhalation on the response to nasal challenge with antigen of allergic subjects. (1990) (135)
Influx of kininogens into nasal secretions after antigen challenge of allergic individuals. (1985) (133)
Kinins are generated in nasal secretions during natural rhinovirus colds. (1990) (130)
Human rhinovirus infection enhances airway epithelial cell production of growth factors involved in airway remodeling. (2008) (126)
Differential regulation of epithelial-derived C-C chemokine expression by IL-4 and the glucocorticoid budesonide. (1999) (125)
Stable Expression of the Human Kinin B1 Receptor in Chinese Hamster Ovary Cells (1997) (121)
Oral prednisone therapy in experimental rhinovirus infections. (1996) (118)
Identification of a chymotrypsin-like proteinase in human mast cells. (1986) (117)
Interleukin-17A modulates human airway epithelial responses to human rhinovirus infection. (2007) (117)
A randomized controlled trial of glucocorticoid prophylaxis against experimental rhinovirus infection. (1990) (114)
Production of granulocyte-macrophage colony-stimulating factor by cultured human tracheal epithelial cells. (1992) (113)
Role of viral infections in asthma and chronic obstructive pulmonary disease. (2006) (109)
Responses to ragweed-pollen nasal challenge before and after immunotherapy. (1989) (107)
Human lung macrophage-derived histamine-releasing activity is due to IgE-dependent factors. (1986) (107)
Relationship between the early, late, and rechallenge reaction to nasal challenge with antigen: observations on the role of inflammatory mediators and cells. (1990) (107)
Plasma kallikrein during experimentally induced allergic rhinitis: role in kinin formation and contribution to TAME-esterase activity in nasal secretions. (1986) (106)
TNFα and IFNγ synergistically enhance transcriptional activation of CXCL10 in human airway smooth muscle cells via STAT-1, NF-κB, and the transcriptional coactivator CREB-binding protein. (2010) (104)
Repression of Inflammatory Gene Expression in Human Pulmonary Epithelial Cells by Small-Molecule IκB Kinase Inhibitors (2007) (104)
Upper respiratory tract environmental tobacco smoke sensitivity. (1991) (104)
In vivo release of inflammatory mediators by hyperosmolar solutions. (1988) (104)
Role of NF-κB in Cytokine Production Induced from Human Airway Epithelial Cells by Rhinovirus Infection1 (2000) (101)
Human lung macrophages induce histamine release from basophils and mast cells. (1985) (101)
Studies on the allergic and nonallergic nasal inflammation. (1988) (98)
Role of nasal nitric oxide in the resolution of experimental rhinovirus infection. (2004) (98)
Basophil histamine release induced by a substance from stimulated human platelets. (1986) (97)
Human eosinophil-granule major basic protein and synthetic polycations induce airway hyperresponsiveness in vivo dependent on bradykinin generation. (1995) (97)
Characterization of vagal afferent subtypes stimulated by bradykinin in guinea pig trachea. (1999) (95)
Influence of the Cytosolic Carboxyl Termini of Human B1 and B2 Kinin Receptors on Receptor Sequestration, Ligand Internalization, and Signal Transduction* (1998) (94)
Tryptase and histamine as markers to evaluate mast cell activation during the responses to nasal challenge with allergen, cold, dry air, and hyperosmolar solutions. (1992) (93)
Observations on the pathogenesis of nasal priming. (1989) (92)
Terfenadine, an H1 antihistamine, inhibits histamine release in vivo in the human. (1990) (90)
Evidence that enhanced nasal reactivity to bradykinin in patients with symptomatic allergy is mediated by neural reflexes. (1996) (88)
Syk Associates with Clathrin and Mediates Phosphatidylinositol 3-Kinase Activation during Human Rhinovirus Internalization1 (2008) (84)
Effects of prednisone on the cellular responses and release of cytokines and mediators after segmental allergen challenge of asthmatic subjects. (2001) (84)
Concentrations of glandular kallikrein in human nasal secretions increase during experimentally induced allergic rhinitis. (1986) (84)
The human nasal response to capsaicin. (1994) (83)
A double-blind study of the discontinuation of ragweed immunotherapy. (1997) (81)
Major basic protein and eosinophil-derived neurotoxin concentrations in nasal-lavage fluid after antigen challenge: effect of systemic corticosteroids and relationship to eosinophil influx. (1989) (80)
Cigarette smoke modulates rhinovirus-induced airway epithelial cell chemokine production (2009) (79)
Characterization and localization of human renal kininogen. (1981) (77)
Rhinovirus infection induces expression of type 2 nitric oxide synthase in human respiratory epithelial cells in vitro and in vivo. (2001) (76)
Detection and partial characterization of a human mast cell carboxypeptidase. (1987) (75)
Identification of human lung mast cell kininogenase as tryptase and relevance of tryptase kininogenase activity. (1988) (75)
Dose-dependent effects of capsaicin nasal challenge: in vivo evidence of human airway neurogenic inflammation. (1997) (73)
Kinin metabolism in human nasal secretions during experimentally induced allergic rhinitis. (1987) (72)
Characterization of kinin receptors on human synovial cells and upregulation of receptor number by interleukin-1. (1992) (72)
Platelet activation in the lung after antigen challenge in a model of allergic asthma. (1992) (72)
Role of IL-17A and neutrophils in fibrosis in experimental hypersensitivity pneumonitis. (2013) (71)
Local generation of sulfidopeptide leukotrienes upon nasal provocation with cold, dry air. (1986) (70)
The osmolality of nasal secretions increases when inflammatory mediators are released in response to inhalation of cold, dry air. (1988) (70)
The effect of azelastine on the early allergic response (1992) (68)
The effect of cetirizine on early allergic response (1989) (68)
Characterization and origin of immunoreactive glandular kallikrein in rat plasma. (1981) (68)
TNFα and IFNγ Synergistically Enhance Transcriptional Activation of CXCL10 in Human Airway Smooth Muscle Cells via STAT-1, NF-κB, and the Transcriptional Coactivator CREB-binding Protein (2010) (67)
A human lung mast cell chymotrypsin-like enzyme. Identification and partial characterization. (1986) (64)
Syk Is Downstream of Intercellular Adhesion Molecule-1 and Mediates Human Rhinovirus Activation of p38 MAPK in Airway Epithelial Cells1 (2006) (64)
Cigarette Smoke Modulates Expression of Human Rhinovirus-Induced Airway Epithelial Host Defense Genes (2012) (64)
Nitric oxide and the common cold (2005) (62)
Viral-associated exacerbations of asthma and COPD (2007) (61)
Histamine may induce airway remodeling through release of epidermal growth factor receptor ligands from bronchial epithelial cells (2012) (61)
Effect of intranasal capsaicin on symptoms and mediator release. (1991) (60)
IGF1R is an entry receptor for respiratory syncytial virus (2020) (59)
Human rhinovirus infection up-regulates MMP-9 production in airway epithelial cells via NF-{kappa}B. (2010) (59)
Demonstration of inhibition of mediator release from human mast cells by azatadine base. In vivo and in vitro evaluation. (1986) (58)
Theophylline reduces histamine release during pollen-induced rhinitis. (1986) (57)
Mutation of Tyrosine in the Conserved NPXXY Sequence Leads to Constitutive Phosphorylation and Internalization, but Not Signaling, of the Human B2 Bradykinin Receptor* (2004) (56)
Bradykinin antagonists. (1991) (56)
Comparison of the responses of B1 and B2 kinin receptors to agonist stimulation. (1999) (56)
Neutrophil transmigration across human airway epithelial monolayers: mechanisms and dependence on electrical resistance. (2000) (56)
Radioimmunoassay of human high molecular weight kininogen in normal and deficient plasmas. (1980) (55)
Effects of tumor necrosis factor-α, epidermal growth factor and transforming growth factor-α on interleukin-8 production by, and human rhinovirus replication in, bronchial epithelial cells (2001) (54)
Characteristics of Early-Onset vs Late-Onset Colorectal Cancer: A Review. (2021) (54)
Activation of Antiviral Protein Kinase Leads to Immunoglobulin E Class Switching in Human B Cells (1998) (53)
Inflammatory mediators and mechanisms of release from purified human basophils and mast cells. (1984) (53)
Cultured human synovial fibroblasts rapidly metabolize kinins and neuropeptides. (1992) (53)
Human lung macrophages enhance and inhibit lymphocyte proliferation. (1984) (53)
Human rhinovirus-induced epithelial production of CXCL10 is dependent upon IFN regulatory factor-1. (2010) (52)
Interferon regulatory factor 7 regulates airway epithelial cell responses to human rhinovirus infection (2016) (52)
Disassociation of the release of histamine and arachidonic acid metabolites from osmotically activated basophils and human lung mast cells. (1990) (51)
Effects of intranasal administration of endothelin-1 to allergic and nonallergic individuals. (1995) (51)
Arachidonic acid metabolites during nasal challenge. (1987) (51)
The effect of a topical tricyclic antihistamine on the response of the nasal mucosa to challenge with cold, dry air and histamine. (1987) (51)
Distribution of immunoreactive kallikrein along the rat nephron. (1983) (51)
Induction of histamine release from human skin mast cells by bradykinin analogs. (1989) (50)
Association of mechanical bowel preparation with oral antibiotics and anastomotic leak following left sided colorectal resection: an international, multi‐centre, prospective audit (2018) (50)
Studies on the relationships between sensitivity to cold, dry air, hyperosmolal solutions, and histamine in the adult nose. (1990) (49)
Nasal provocation with allergen induces a secondary serum IgE antibody response. (1997) (49)
Ozone exposure in humans: inflammatory, small and peripheral airway responses. (1995) (49)
Dexamethasone inhibits plasminogen activator activity in experimental pemphigus in vivo but does not block acantholysis. (1986) (49)
Epithelial shedding is associated with nasal reactions to cold, dry air. (2006) (48)
Synergistic Expression of the CXCL10 Gene in Response to IL-1β and IFN-γ Involves NF-κB, Phosphorylation of STAT1 at Tyr701, and Acetylation of Histones H3 and H4 (2013) (48)
Nitric oxide inhibits rhinovirus-induced granulocyte macrophage colony-stimulating factor production in bronchial epithelial cells. (2001) (47)
Intranasal beclomethasone inhibits antigen-induced nasal hyperresponsiveness to histamine. (1992) (47)
Induction of B7-H1 and B7-DC expression on airway epithelial cells by the Toll-like receptor 3 agonist double-stranded RNA and human rhinovirus infection: In vivo and in vitro studies. (2008) (47)
Immunoglobulin E-mediated release of a kininogenase from purified human lung mast cells. (1985) (46)
Rhinovirus infection interferes with induction of tolerance to aeroantigens through OX40 ligand, thymic stromal lymphopoietin, and IL-33. (2016) (46)
Allergen-induced hyperresponsiveness to bradykinin is more pronounced than that to methacholine. (1995) (46)
Sinus mucosal IL-8 gene expression in chronic rhinosinusitis. (1999) (46)
Mediator release during nasal provocation. A model to investigate the pathophysiology of rhinitis. (1985) (46)
Measles virus infection synergizes with IL-4 in IgE class switching. (1999) (45)
Soluble intracellular adhesion molecule 1 in bronchoalveolar lavage fluid of allergic subjects following segmental antigen challenge. (1994) (44)
An international multicentre prospective audit of elective rectal cancer surgery; operative approach versus outcome, including transanal total mesorectal excision (TaTME) (2018) (43)
Virus-induced modulation of lower airway diseases: Pathogenesis and pharmacologic approaches to treatment (2014) (43)
Preincubation of human synovial cells with IL-1 modulates prostaglandin E2 release in response to bradykinin. (1989) (42)
Antigen-provoked increase in histamine reactivity. Observations on mechanisms. (1991) (41)
Inflammatory mediators in nasal secretions during induced rhinitis (1986) (41)
Nitric oxide inhibits human rhinovirus-induced transcriptional activation of CXCL10 in airway epithelial cells. (2009) (41)
Experimentally induced nasal allergic responses. (1988) (40)
Lack of nitric oxide synthase depresses ion transporting enzyme function in cardiac muscle. (2002) (40)
Glucocorticoids do not alter peptidase expression on a human bronchial epithelial cell line. (1994) (40)
Selective Transcriptional Down-Regulation of Human Rhinovirus-Induced Production of CXCL10 from Airway Epithelial Cells via the MEK1 Pathway 1 (2009) (39)
The kinin system in rhinitis and asthma (1998) (38)
Acute respiratory response to prolonged, moderate levels of sidestream tobacco smoke. (1998) (38)
Chronic arthritis down-regulates peripheral mu-opioid receptor expression with concomitant loss of endomorphin 1 antinociception. (2005) (38)
Kallikrein-kinin and renin-angiotensin systems in rat renal lymph. (1984) (37)
Role of rhinovirus infections in asthma. (2011) (37)
Profiling of bisenoic prostaglandins and thromboxane B2 in bronchoalveolar fluid from the lower respiratory tract of human subjects by combined capillary gas chromatography-mass spectrometry. (1988) (36)
Toll‐like receptor 3 blockade in rhinovirus‐induced experimental asthma exacerbations: A randomized controlled study (2017) (36)
A European survey of bowel preparation in colorectal surgery (2017) (36)
Antimicrobial peptides in lung transplant recipients with bronchiolitis obliterans syndrome (2008) (36)
The nasal response to histamine challenge: effect of the pollen season and immunotherapy. (1992) (35)
Antigen‐specific IgE and IgA antibodies in bronchoalveolar lavage fluid are associated with stronger antigen‐induced late phase reactions (2001) (35)
Is histamine responsible for the symptoms of rhinovirus colds? A look at the inflammatory mediators following infection. (1988) (35)
Rhinovirus in the Pathogenesis and Clinical Course of Asthma. (2015) (34)
Plasma extravasation through neuronal stimulation in human nasal mucosa in the setting of allergic rhinitis. (1998) (34)
Opposing Effects of Smoking in Ulcerative Colitis and Crohn's Disease May Be Explained by Differential Effects on Dendritic Cells (2014) (34)
Transcriptional and epigenetic modulation of human rhinovirus-induced CXCL10 production by cigarette smoke. (2014) (33)
Clinical and immunologic effects of component peptides in Allervax Cat. (1997) (33)
Dissociation of bradykinin-induced plasma exudation and reactivity in the peripheral airways. (1996) (33)
Localization of immunoreactive tissue kallikrein in human trachea. (1993) (33)
Differences between basophils and mast cells: failure to detect Charcot-Leyden crystal protein (lysophospholipase) and eosinophil granule major basic protein in human mast cells. (1986) (33)
A sensitive colorimetric assay for the release of tryptase from human lung mast cells in vitro. (1993) (32)
Selective Prostacyclin Receptor Agonism Augments Glucocorticoid-Induced Gene Expression in Human Bronchial Epithelial Cells1 (2009) (32)
Relationship between histamine and physiological changes during the early response to nasal antigen provocation. (1999) (32)
Effects of loratadine and terfenadine on the induced nasal allergic reaction. (1996) (31)
Attenuation of allergen sensitivity early in the course of ragweed immunotherapy. (1989) (31)
The effect of a leukotriene antagonist on the early response to antigen (1990) (30)
Comparison of the in‐vivo and in‐vitro response to ragweed immunotherapy in children and adults with ragweed‐induced rhinitis (1990) (30)
Cold dry air-induced rhinitis: effect of inhalation and exhalation through the nose. (1995) (29)
Pharmacology of nasal provocation with bradykinin: studies of tachyphylaxis, cyclooxygenase inhibition, alpha-adrenergic stimulation, and receptor subtype. (1991) (29)
Are we getting necrotizing soft tissue infections right? A 10‐year review (2014) (29)
The role of helix 8 and of the cytosolic C‐termini in the internalization and signal transduction of B1 and B2 bradykinin receptors (2004) (29)
The immunological similarity of rat glandular kallikreins. (1977) (28)
Airway neural responses to kinins: tachyphylaxis and role of receptor subtypes. (1999) (28)
Tumor necrosis factor α decreases aquaporin 3 expression in intestinal epithelial cells through inhibition of constitutive transcription (2017) (27)
Stronger nasal responsiveness to cold air in individuals with rhinitis and asthma, compared with rhinitis alone (2006) (27)
Kinins are generated in nasal secretions during influenza A infections in ferrets. (1990) (27)
Differential expression of interferon-lambda receptor 1 splice variants determines the magnitude of the antiviral response induced by interferon-lambda 3 in human immune cells (2020) (27)
Theophylline reduces the response to nasal challenge with antigen. (1985) (27)
Rhinovirus replication and innate immunity in highly differentiated human airway epithelial cells (2019) (27)
TLR2 Activation Limits Rhinovirus-Stimulated CXCL-10 by Attenuating IRAK-1–Dependent IL-33 Receptor Signaling in Human Bronchial Epithelial Cells (2016) (27)
Inhibition of human bronchial kallikrein in asthma. (1989) (27)
Nitric oxide inhibits IFN regulatory factor 1 and nuclear factor-kappaB pathways in rhinovirus-infected epithelial cells. (2009) (26)
Safety of primary anastomosis following emergency left sided colorectal resection: an international, multi‐centre prospective audit (2018) (26)
Effects of tumor necrosis factor-alpha, epidermal growth factor and transforming growth factor-alpha on interleukin-8 production by, and human rhinovirus replication in, bronchial epithelial cells. (2001) (26)
Transient Exposure of Human Bronchial Epithelial Cells to Cytokines Leads to Persistent Increased Expression of ICAM-1 (2001) (25)
In vivo and in vitro effects of antihistamines on mast cell mediator release: a potentially important property in the treatment of allergic disease. (1989) (24)
A competitive kinin receptor antagonist, [DArg0, Hyp3, DPhe7]-bradykinin, does not affect the response to nasal provocation with bradykinin. (1991) (24)
Daily variations of serum diamine oxidase and the influence of H1 and H2 blockers: A critical approach to routine diamine oxidase assessment (1998) (23)
Rhinovirus specific IgE can be detected in human sera. (2013) (23)
Chemokine release from human rhinovirus-infected airway epithelial cells promotes fibroblast migration. (2016) (23)
Human Rhinovirus Infection of Epithelial Cells Modulates Airway Smooth Muscle Migration (2017) (23)
Rhinovirus has the unique ability to directly activate human T cells in vitro. (2013) (23)
Nasal challenge with cold, dry air induces a late-phase reaction. (1988) (23)
Role of human rhinovirus in triggering human airway epithelial-mesenchymal transition (2017) (23)
Local application of atropine attenuates the upper airway reaction to cold, dry air. (1992) (23)
Rhinovirus and Bacteria Synergistically Induce IL-17C Release from Human Airway Epithelial Cells To Promote Neutrophil Recruitment (2018) (23)
Steroid-induced reduction of histamine release does not alter the clinical nasal response to cold, dry air. (1991) (22)
Upper airway viral infections (2007) (22)
Airways hyper‐responsiveness to bradykinin and methacholine: effects of inhaled fluticasone (2002) (20)
Inhibition of the response to nasal provocation with bradykinin by HOE-140: efficacy and duration of action. (1995) (20)
Mechanisms of mediator release from human skin mast cells upon stimulation by the bradykinin analog, [DArg0-Hyp3-DPhe7]bradykinin. (1991) (20)
Human rhinovirus-induced ISG15 selectively modulates epithelial antiviral immunity (2014) (20)
Human β-defensin-2 production upon viral and bacterial co-infection is attenuated in COPD (2017) (19)
Rhinovirus-Induced MMP-9 Expression Is Dependent on Fra-1, Which Is Modulated by Formoterol and Dexamethasone (2012) (19)
A new kinin moiety in human plasma kininogens. (1988) (19)
Cigarette smoke enhances human rhinovirus-induced CXCL8 production via HuR-mediated mRNA stabilization in human airway epithelial cells (2013) (18)
Effects of restriction of sodium or administration of fludrocortisone on parotid salivary kallikrein in man. (1982) (18)
4,5-Dihydro-1H-imidazol-2-yl)-[4-(4-isopropoxy-benzyl)-phenyl]-amine (RO1138452) Is a Selective, Pseudo-Irreversible Orthosteric Antagonist at the Prostacyclin (IP)-Receptor Expressed by Human Airway Epithelial Cells: IP-Receptor-Mediated Inhibition of CXCL9 and CXCL10 Release (2008) (17)
The role of defensins in virus-induced asthma (2006) (17)
The pathophysiology of human mast cells. In vitro and in vivo function. (1987) (17)
Rapid purification of a prekallikrein from rat pancreas. (1981) (17)
Evaluating the incidence of pathological complete response in current international rectal cancer practice: the barriers to widespread safe deferral of surgery (2018) (17)
Origin of late phase histamine release. (1996) (17)
Effect of alterations in extracellular fluid volume on urinary kallikrein in the conscious rat. (1982) (16)
Budesonide in grass pollen rhinitis. (1992) (16)
Bradykinin is a potent and relatively selective stimulus for cytosolic calcium elevation in human synovial cells. (1994) (16)
Bradykinin effects in guinea pig tracheal epithelial cells are mediated through a B2 kinin receptor and can be inhibited by the selective antagonist Hoe 140. (1993) (16)
Ketotifen reduces sneezing but not histamine release following nasal challenge with antigen (1990) (16)
The effects of the nasal antihistamines olopatadine and azelastine in nasal allergen provocation. (2008) (15)
CFD SIMULATION OF UNDERGROUND COAL DUST EXPLOSIONS AND ACTIVE EXPLOSION BARRIERS (2010) (15)
Rhinovirus-bacteria coexposure synergistically induces CCL20 production from human bronchial epithelial cells. (2017) (14)
The effect of a histamine synthesis inhibitor on the immediate nasal allergic reaction (1987) (14)
PGC-1α mediates a metabolic host defense response in human airway epithelium during rhinovirus infections (2021) (14)
Modulation of transcriptional responses by poly(I:C) and human rhinovirus: effect of long-acting β₂-adrenoceptor agonists. (2013) (14)
The impact of conversion on the risk of major complication following laparoscopic colonic surgery: an international, multicentre prospective audit (2018) (14)
Enhancement of afferent nerve excitability in the airways by allergic inflammation. (1995) (12)
Bradykinin analog induce histamine release from human skin mast cells. (1989) (12)
The effects of H1 antihistamines on the early allergic response. (1989) (11)
Observations on nasal late phase reactions. (1987) (11)
285 In vivo release of histamine by hyperosmolar stimuli (1985) (10)
Is leukotriene B4 an important mediator in human IgE-mediated allergic reactions? (1987) (10)
Immunopharmacology of Nasal Allergic Reactions (1988) (10)
Ragweed IgE and IgG4 antibody in nasal secretions during immunotherapy (1990) (10)
Treatment with hot, humid air reduces the nasal response to allergen challenge. (1997) (10)
Allergen-induced changes in airway responsiveness are not related to indices of airway edema. (2001) (10)
37 Cold, dry air (CDA) and histamine (HIST) induce more potent responses in perennial rhinitics compared to normal individuals (1991) (10)
531 Nasal cold, dry air (CDA) challenge results in stronger nasal and pulmonary responses in asthmatics compared to patients with rhinitis (1996) (10)
Localized antigen challenge of the nasal mucosa. (1990) (9)
Kinins in the pathogenesis of human airway diseases. (1994) (9)
Rhinovirus Induces Basolateral Release of IL-17C in Highly Differentiated Airway Epithelial Cells (2020) (9)
Effects of a single-dose pretreatment with captopril on the immediate response to nasal challenge with allergen. (1990) (9)
Alanine screening of the intracellular loops of the human bradykinin B2 receptor – effects on receptor maintenance, G protein activation and internalization (2009) (9)
456 Nasal challenge with antigen (AG) leads to increased sensitivity to histamine (1988) (9)
Rhinovirus-Induced Modulation of Epithelial Phenotype: Role in Asthma (2020) (8)
Multidisciplinary team response to a mass burn casualty event: outcomes and implications (2011) (8)
The role of kinins in human allergic disease. (1986) (8)
The Pulmonary Epithelium in Health and Disease (2008) (8)
Biology of Epithelial Cells (2009) (7)
Pharmacology of upper airways challenge. (1987) (7)
Mechanisms of prostanoid synthesis in human synovial cells: Cytokine-peptide synergism (1996) (7)
Hot, Humid Air Partially Decreases the Response to Nasal Challenge with Antigen (1995) (7)
224 In vivo response to platelet derived histamine releasing factor (1988) (7)
Reproducibility of nasal allergen challenge in evaluating the efficacy of intranasal corticosteroid treatment (2010) (7)
Lack of Effect of Hot, Humid Air on Response to Nasal Challenge with Histamine (1996) (7)
38 Unilateral cold dry air (CDA) nasal challenge induces a contralateral reflex response (1991) (6)
A Toolbox for Studying Respiratory Viral Infections Using Air-Liquid Interface Cultures of Human Airway Epithelial Cells. (2021) (6)
Modulation of epithelial biology by rhinovirus infection: role in inflammatory airway diseases (2011) (6)
Expression of the Chemokine Rantes In Human Epithelial-cells (1994) (6)
Creatine supplementation as an exercise performance enhancer for patients with COPD? An idea to run with (2005) (6)
Modulation of kinin responses in human synovium by interleukin-1. (1992) (6)
Interferon gamma decreases intestinal epithelial aquaporin 3 expression through downregulation of constitutive transcription (2018) (6)
IgE-mediated release of inflammatory mediators from human basophils and mast cells in vitro and in vivo (1984) (6)
Respiratory Viral and Bacterial Exacerbations of COPD—The Role of the Airway Epithelium (2022) (5)
Histamine stimulation of the nasal mucosa does not induce prostaglandin or leukotriene generation or induce methacholine hyperresponsiveness. (1991) (5)
36 Epithelial cell detachment is observed during the nasal reaction to cold, dry air (CDA) (1991) (5)
Human plasma prekallikrein and high molecular weight kininogen decrease during parturition. (1984) (4)
The location of prekallikrein in the rat pancreas [proceedings]. (1977) (4)
Current opinions and practices for the management of acute appendicitis: an international survey (2020) (4)
Mediators in nasal secretions of patients with allergic rhinitis (1985) (4)
The role of inflammatory mediators in allergic rhinitis. (1986) (4)
Interaction of platelet-activating factor with cultured guinea pig tracheal epithelial cells. (1991) (4)
831 The effects of multiple nasal antigen challenges on the asthmatic airways (2000) (4)
International survey on opinions and use of minimally invasive surgery in small bowel neuroendocrine neoplasms. (2021) (3)
Immunoreactive kallikrein in rat renal lymph. (1983) (3)
Specific Assay of Negative Strand Template to Quantify Intracellular Levels of Rhinovirus Double-Stranded RNA (2021) (3)
Genomic determinants implicated in the glucocorticoid-mediated induction of KLF9 in pulmonary epithelial cells (2020) (3)
Kinins as mediators of human allergic reactions. (1986) (3)
Kininogens in nasal secretions after allergen challenge. (1986) (3)
49 Persistent efficacy of a combination antihistamine/analgesic/decongestant product (CAAD) the morning after a bedtime dose (1991) (3)
289 Kininogenase activity in bronchoalveolar lavage (BAL) fluids in asthma (1985) (3)
Genomic determinants implicated in the glucocorticoid-mediated induction of KLF9 in pulmonary epithelial cells. (2020) (3)
999 Prophylactic use of topical triamcinolone acetonide nasal inhaler in patients with seasonal allergic rhinitis (1996) (2)
Response of Respiratory Epithelial Cells to Inflammatory Stimuli (1990) (2)
Histamine release from human basophils is induced by IgE-dependent factor(s) derived from human lung macrophages and an Fc epsilon receptor-positive human B cell line. (1985) (2)
Publisher Correction: IGF1R is an entry receptor for respiratory syncytial virus (2020) (2)
Cystic Fibrosis: Detecting frailty in an outpatient clinic (2016) (2)
254 Body composition; expect the unexpected! (2012) (2)
Characterization of GTP-binding proteins coupled to inhibition of adenylyl cyclase in guinea pig tracheal epithelial cells. (1994) (2)
227 Correlation of basophil responsiveness to platelet-derived Histamine Releasing Factor (PD-HRF) and deuterium oxide (D2O) (1988) (2)
Are We Missing the Opportunity to Measure Muscle Mass on Computed Tomography Thorax? (2020) (2)
460 The relationship between atopy and the response to cold dry air (CDA) and histamine (H) challenge in perennial rhinitis (PR) (1988) (2)
Pre-existing human rhinovirus infection modulates host response to secondary bacterial infections (2014) (1)
Editorial: The Response of Mucosal Epithelial Cells to Infections (2020) (1)
Modulation in vitro of hydrogen peroxide toxicity to human tracheal epithelial cells by neutrophils (1988) (1)
Evaluation of a bedtime dose of a combination antihistamine/analgesic/decongestant product on antigen challenge the next morning (1992) (1)
219 Relationships between symptoms, mediators, and cells in the late-phase reaction to nasal antigen challenge (2000) (1)
The Effect of Pulmonary Rehabilitation on Arterial Stiffness in Patients with Chronic Obstructive Pulmonary Disease (COPD) (2009) (1)
Recent studies on the rule of kinins in inflammatory diseases of human airways. (1989) (1)
The role of kinins in nonallergic rhinitis (1988) (1)
Isolated bone marrow metastases of colorectal adenocarcinoma (2018) (1)
344 Which grip device to grip? A comparison of hand grip strength dynamometers in adult patients with cystic fibrosis (2017) (1)
196 Change in body composition pre and post lung transplant in adult CF patients (2016) (1)
Human Rhinovirus Increases MMP-9 Expression In Vitro and In Vivo. (2009) (1)
191 Test–retest reliability of bioelectrical impedance and hand grip strength over 1 year in adult patients with cystic fibrosis (2016) (1)
277 Transformational care at the All Wales Adult CF Centre (AWACFC) – is ivacaftor making us fat? The impact of ivacaftor (Kalydeco®) on body composition (2015) (1)
Burning up the disposable income. (1988) (1)
Detecting Osteoporosis in Patients with COPD Attending Pulmonary Rehabilitation. (2009) (1)
Migration of the contractile phenotype of human airway smooth muscle cells in response to supernatants from rhinovirus infected human bronchial epithelial cells (2014) (1)
Kinins and mast cell-related diseases (1993) (1)
The global cost of pelvic exenteration: in‐hospital perioperative costs (2020) (1)
Human rhinovirus infection of human bronchial epithelial cells results in migration of human airway smooth muscle cells (2014) (1)
58 Airways hyperreactivity to bradykinin (BK) and methacholine (Mch): Differential effects of inhaled fluticasone (2000) (1)
Cyclic stretch augments human rhinovirus induced inflammatory responses in airway epithelial cells (2014) (1)
458 Localized antigen challenge of the nasal mucosa (1988) (1)
Generation of kinins in vivo during allergic rhinitis (1988) (1)
200 The effect of a histamine synthesis inhibitor on the immediate allergic reaction (1985) (1)
Hot Horizon Hot Vertical: 'David Proud Makes a Film: Bruce McLean Makes a Painting' (2004) (0)
Cigarette Smoke Inhibits Human Rhinovirus-Induced Viperin Expression In Airway Epithelial Cells (2011) (0)
In Honour of Paul Kallós (1987) (0)
Cardiac transplantation. (1985) (0)
Poly(I:C) And Human Rhinovirus Attenuate Simple GRE-Dependent Transcription (2012) (0)
Mechanisms Of CXCL8 Enhancement By The Combination Of Human Rhinovirus And Cigarette Smoke (2012) (0)
Tobacco Smoke Sensitivity1-4 (1991) (0)
Epithelial Cells of Donor Origin after Allogeneic HCT: Result of Cell Fusion, Transdifferentiation (plasticity) or Transfer of Epithelial Cell Precursors with the Graft? (2008) (0)
F.18. Nasal Epithelial Cells of Donor Origin After Allogeneic Hematopoeitic Cell Transplantation (HCT): Result of Stem-cell Plasticity, Cell-fusion or Transfer of Epithelial Cell Precursors with the Graft? (2009) (0)
Pro-Inflammatory Stimuli Reduce Glucocorticoid-Dependent Transcription: A Form Of Induced Resistance To Glucocorticoids (2011) (0)
Contents, Vol. 82, 1987 (1987) (0)
P092 Exploring the association between hand grip strength (HGS) and lung function (FEV1%) in cystic fibrosis: does HGS offer an insight into pulmonary function? (2022) (0)
something Smells Fishy: Split-thickness Skin Graft Destruction By Shewanella Putrefasciens : pr81p (2012) (0)
Pulmonary Antimicrobial Peptide Expression in Lung Transplant Recipients with Bronchiolitis Obliterans Syndrome (BOS) (2008) (0)
Modulation of Human Rhinovirus (HRV)-Induced Airway Epithelial Cell Responses by Cigarette Smoke Extract (CSE). (2009) (0)
Modulation Of Human Rhinovirus (HRV)-Induced Expression Of The Ubiquitin-Like Modifier, ISG15, By Cigarette Smoke Extract (CSE) In Human Bronchial Epithelial Cells (2011) (0)
The in-Vitro Effect of Cigarette Smoke Extract on Monocyte-Derived Dendritic Cell Phenotypes is Different in Crohn's Disease Compared With Ulcerative Colitis Patients (2011) (0)
54 Reproducibility of a nasal allergen challenge model in evaluating the efficacy of intranasal beclomethasone (BEC) (1996) (0)
Acetylation of Histones H 3 and H 4 , 701 B , Phosphorylation of STAT 1 at Tyr κ Involves NF-γ and IFN-β in Response to IL-1 Synergistic Expression of the CXCL 10 Gene Proud (2013) (0)
The Complete Contempt and 8 Art Ads (1997) (0)
WS10.6 Are cystic fibrosis patients frail? Is 50 the new 80? (2016) (0)
Influence of the cytosolic carboxy termini of human bl and b2 kinin receptors on ligand internalization (1996) (0)
Human lung macrophages (HLM) produce lymphocyte activating factors which are distinct from interleukin-1 (IL-1) (1984) (0)
Statin Therapy Is Associated With Decreased Improvements In Shuttle Walk Performance In Patients with COPD Undergoing Pulmonary Rehabilitation (2010) (0)
Mechanisms Of Human Rhinovirus-Induced CXCL10 Inhibition By Cigarette Smoke (2011) (0)
Reverse Genetics and Rhinovirus-A New Approach to an Old Problem? (2018) (0)
Increased Human Rhinovirus Replication Following Corticosteroid and Diesel Exhaust Particulate Exposures (2022) (0)
NF-κB Inhibition Attenuates Human Rhinovirus Replication Following Corticosteroid and Diesel Exhaust Particulate Exposures (2023) (0)
P281 Body composition in adults with cystic fibrosis – are measurements taken using single frequency and multifrequency devices interchangeable? (2020) (0)
Repression of Inflammatory Gene Expression in Human Pulmonary Epithelial Cells by Small-Molecule I (cid:1) B Kinase Inhibitors □ S (2007) (0)
Nitric Oxide (NO) Inhibits Human Rhinovirus (HRV)-16-Induced Transcription of IP-10 (CXCL10) in Human Airway Epithelial Cells (HAE) (2007) (0)
Publisher Correction: IGF1R is an entry receptor for respiratory syncytial virus (2020) (0)
The Pavement and Bridge Gallery Project (2005) (0)
Mo1729 Differential Effect of Cigarette Smoke Extract Modifies CD103 and CXCR3 Expressions of Monocyte-Derived Dendritic Cells From Crohn's Disease and Ulcerative Colitis Patients (2014) (0)
Glucocorticoid Budesonide C-C Chemokine Expression by IL-4 and the Differential Regulation of Epithelial-Derived (2013) (0)
An idea to run with performance enhancer for patients with COPD ? Creatine supplementation as an exercise (2005) (0)
This information is current as Epithelial Cells Receptor Signaling in Human Bronchial Dependent IL-33 − Attenuating IRAK-1 Rhinovirus-Stimulated CXCL-10 by TLR 2 Activation Limits (2016) (0)
Epithelial Cell Innate Immune Responses to Rhinovirus Infection (2004) (0)
Interferon regulatory factor 7 regulates airway epithelial cell responses to human rhinovirus infection (2016) (0)
In vitro and in vivo induction of B7-H1 and B7-DC expression by human rhinovirus infection of airway epithelial cells (2007) (0)
P192 To be or not to be (happy): fat is the question? (2018) (0)
CellsExpression in Human Bronchial Epithelial Augments Glucocorticoid-Induced Gene Selective Prostacyclin Receptor Agonism (2009) (0)
Host response to human rhinovirus infection: toward targeted treatment strategies (2009) (0)
Chapter 12 – Kinin Actions in the Human Airways: Modulation by Allergic Inflammation (1998) (0)
Rhinovirus C Infection Activates Cytoskeletal Signaling and Results in Barrier Loss in Highly Differentiated Airway Epithelial Cells (2020) (0)
A Retrospective Study of Nutritional Status in Patients with Bronchiectasis Pre and Post Pulmonary Rehabilitation (2014) (0)
Reactive oxygen species as mediators of disease progression and therapeutic response in colorectal cancer. (2023) (0)
In vitro and in vivo induction of B7-H1 and B7-DC expression by human rhinovirus infection of airway epithelial cells (46.5) (2007) (0)
Perspectives on rectal cancer surgical prehabilitation: time to consider the pelvic floor? (2022) (0)
Sodium-retaining steroids increase parotid salivary kallikrein. (1983) (0)
Upregulation Of Epithelial Stromal Interation1 (EPSTI1) In Human Bronchial Epithelial Cells Following Human Rhinovirus Infection (2012) (0)
TNFα and IFNγ Phosphorylate RNA Polymerase II To Synergistically Enhance CXCL-10 Release from Human Airway Smooth Muscle Cells. (2009) (0)
Pulmonary rehabilitation improves cardiovascular risk factors in patients with COPD [Abstract] (2009) (0)
Rhinovirus infection alters cellular architecture of highly differentiated airway epithelial cells (2018) (0)
Defensin 2 Both In Vitro and In Vivo β Epithelial Cell Production of Human Human Rhinovirus Infection Induces Airway (2004) (0)
Sa1774 Cigarette Smoke Extract Decreases Regulatory T-Cells and Increases IFN-Gamma Secreting T-Cells in Peripheral Blood From Crohn's Disease Compared to Ulcerative Colitis Patients: Differential Smoking Effects on Two Types of Inflammatory Bowel Disease (2013) (0)
New Wave Cruise Control (2001) (0)
Activation of p38 MAPK in Airway Epithelial Molecule-1 and Mediates Human Rhinovirus Syk Is Downstream of Intercellular Adhesion (2006) (0)
The antimicrobial peptide, human beta defensin-2, in acute rejection after human lung transplantation (2006) (0)
Human Rhinovirus-Induced LSG56 Expression Is Inhibited By Cigarette Smoke In Human Airway Epithelial Cells (2011) (0)
Asthma In Older Adults; Potential Factors To Explain Increased Mortality Rates (2012) (0)
IL-17 Modulates Human Rhinovirus Induced MMP-9 Expression (2010) (0)
Human kinin b! receptor: Ligand binding and functional characterization (1996) (0)
Multi-Omics Reveal Rhinovirus Strain-Specific Metabolic Signatures in Highly Differentiated Human Airway Epithelial Cells (0)
TNFα-induced glucocorticoid resistance: Effect of steroidal and non-steroidal GR agonists, formoterol and inhibition of inflammatory signalling (2012) (0)
Rhinovirus C infection of human airway epithelial cells causes transient replication‐dependent changes in cellular architecture and barrier function (2019) (0)
Synchronous Multifocal Adenomatous Dysplasia and Post-transplant Lymphoproliferative Disorder Confined to the Colon in a Patient with Ulcerative Colitis After Liver Transplant. (2022) (0)
Regulation of Mucosal Immunity by Epithelial Cells (2015) (0)
Kinin Actions in the Human Airways (1998) (0)
Dexamethasone And Formoterol Modulate Rhinovirus-Induced MMP-9 Transcription Via Effects On FRA-1 (2011) (0)
P272 High dose vitamin D supplementation: the patient knows best (2020) (0)
Compléments : Rhinovirus has the unique ability to directly activate human T cells in vitro (2013) (0)
P211 Real-world experience of lumacaftor/ivacaftor combination in Welsh cystic fibrosis patients homozygous for the F508del CFTR mutation with severe lung disease (2020) (0)
IGF1R is an entry receptor for respiratory syncytial virus (2020) (0)
No Sleep 'til Hammersmith (2002) (0)
305 In vivo studies of kinin receptors in allergic rhinitis (1991) (0)
IFN-lambda 3 directly induces antiviral responses in human B and T cells leading to inhibition of HIV-1 infection of CD4+ T cells (2020) (0)
Syk Associates with Clathrin and Mediates (2007) (0)
M25 Outcomes of pulmonary rehabilitation in patients with bronchiectasis (2019) (0)
Su1218 Cigarette Smoke Extract Differentially Affects Expression of CD11c in Monocyte-Derived Dendritic Cells in Crohn's Disease Patients With Active Versus Inactive Disease (2015) (0)
The Pathophysiology of Human Mast Cells (2015) (0)
P206 Putting some backbone into managing low vitamin D (2018) (0)
during Human Rhinovirus Internalization Phosphatidylinositol 3-Kinase Activation Syk Associates with Clathrin and Mediates (2013) (0)
Human Rhinovirus Infection of Primary Bronchial Epithelial Cells Upregulates Prostaglandin E2 Production That Attenuates Transforming Growth Factor Beta-1-Induced Fibroblast-to-Myofibroblast Transition (2020) (0)
30 Kininogens in nasal secretions of allergic individuals (1985) (0)
Nasal Epithelial Cells of Donor Origin After Allogeneic HCT: Result of Stem-Cell Plasticity, Cell-Fusion or Transfer of Epithelial Cell Precursors with the Graft? (2009) (0)
Formoterol and Dexamethasone Dependent on Fra-1, Which Is Modulated by Rhinovirus-Induced MMP-9 Expression Is (2012) (0)
Anti viral protein kinase (PKR) modulates expression of Th2-type responses (1998) (0)
Chapter 25 – Kinins (2002) (0)
Nasal Epithelial Cells Of Donor Origin After Allogeneic Hematopoietic Cell Transplantation (hct): Result Of Cell Fusion, Transdifferentiation Of Hematopoietic Stem Cells Or Transfer Of Epithelial Cell Precursors With The Graft? (2009) (0)
IP-10 expression is induced by human airway epithelial cells (HAE) in response to stimulation with human rhinovirus-16 (HRV-16) (2003) (0)
AllerGen’s 8th research conference (2016) (0)
217 A novel use of BrEaD (breathlessness, eating and drinking) (2014) (0)
Primary Human Airway Fibroblasts Express Intercellular Adhesion Molecule-1 And Are Susceptible To Infection With Rhinovirus (2010) (0)
Cardiac transplant. A nursing perspective. (1985) (0)
216 Hand strength, is it time to get a grip? (2014) (0)
The Epithelium as a Regulator of Airway Inflammation (2008) (0)
Regulation of the Antiviral Protein Viperin in Human Airway Epithelial Cells Infected with Human Rhinovirus (2020) (0)
Human rhinovirus infection of human bronchial epithelial cells results in migration of human bronchial fibroblast cells (2014) (0)
Inhibition of TGFb-induced Fibroblast to Myofibroblast Transition by Conditioned Medium from Human Rhinovirus-infected Airway Epithelial Cells is Mediated by Prostaglandin E2 (2022) (0)
Induction of human airway epithelial to mesenchymal transition upon rhinovirus infection (2014) (0)
P160 “Seeing a trend” - increasing vitamin A levels on elexacaftor/tezacaftor/ivacaftor therapy (2022) (0)
The native and heterologously expressed kinin b2 receptor is coupled to two different g proteins (1996) (0)
Forewarned is forearmed: The cardiovascular time bomb in Cystic Fibrosis (2021) (0)
Inhibition of TGFβ-induced Fibroblast to Myofibroblast Transition by Conditioned Medium From Human Rhinovirus-infected Airway Epithelial Cells is Mediated by Prostaglandin E2 (2022) (0)
492 Effects of immunotherapy on early and late reactions to nasal challenge (1988) (0)
MECHANISMS OF PROSTANOID SYNTHESIS HUMAN SYNOVIAL CELLS: CYTOKINE- PEPTIDE SYNERGISM 1 IN (1996) (0)
RO 1138452 is a selective , pseudo-irreversible orthosteric antagonist at the prostacyclin ( IP )-receptor expressed by human airway epithelial cells : negative IP-receptor-mediated regulation of CXCL 9 and CXCL 10 release (2007) (0)
Contents, Vol. 95, 1991 (1991) (0)
Epithelial Cells (2020) (0)
List of SYBR RT-qPCR primer sequences. (2020) (0)
Mechanisms Of Human Rhinovirus-Induced Viperin Expression In Human Airway Epithelial Cells (2012) (0)
Interferon gamma decreases intestinal epithelial aquaporin 3 expression through downregulation of constitutive transcription (2018) (0)
Preliminary Observations on the Mechanism of Nasal Priming (1988) (0)

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