David R. Brown
#99,459
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Australian neuroscientist
David R. Brown 's AcademicInfluence.com Rankings
David R. Brown biology Degrees
Biology
#14280
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#17990
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Neuroscience
#2740
World Rank
#2811
Historical Rank

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Biology
David R. Brown 's Degrees
- PhD Neuroscience University of Melbourne
Why Is David R. Brown Influential?
(Suggest an Edit or Addition)According to Wikipedia, Professor David Ronald Brown is an Australian-born research scientist notable for his work on prion diseases, which include bovine spongiform encephalopathy and vCJD. His most notable research relates to the metal binding of the protein central to these diseases, the prion protein, and its possible cellular role as an antioxidant.
David R. Brown 's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Helper T cell differentiation is controlled by the cell cycle. (1998) (970)
- Normal prion protein has an activity like that of superoxide dismutase. (1999) (545)
- Prion protein expression and superoxide dismutase activity. (1998) (267)
- Beta 2-microglobulin-dependent NK1.1+ T cells are not essential for T helper cell 2 immune responses (1996) (240)
- Protective vaccination with a recombinant fragment of Clostridium botulinum neurotoxin serotype A expressed from a synthetic gene in Escherichia coli (1995) (165)
- The transforming growth factor-ss superfamily cytokine macrophage inhibitory cytokine-1 is present in high concentrations in the serum of pregnant women. (2000) (162)
- Limited role of CD28-mediated signals in T helper subset differentiation (1996) (136)
- Association of herpesvirus with fibropapillomatosis of the green turtle Chelonia mydas and the loggerhead turtle Caretta caretta in Florida. (1999) (136)
- Human papillomavirus type 11 (HPV-11) neutralizing antibodies in the serum and genital mucosal secretions of African green monkeys immunized with HPV-11 virus-like particles expressed in yeast. (1997) (135)
- Sequence determination of human papillomavirus type 6a and assembly of virus-like particles in Saccharomyces cerevisiae. (1995) (135)
- The human gastrin/cholecystokinin type B receptor gene: alternative splice donor site in exon 4 generates two variant mRNAs. (1993) (118)
- Desiccation tolerance in human cells. (2001) (114)
- Prion disease: A loss of antioxidant function? (2000) (111)
- Upper Respiratory Tract Disease in the Gopher Tortoise Is Caused by Mycoplasma agassizii (1999) (110)
- Regulation of cytokine production during development of autoimmune diabetes induced with multiple low doses of streptozotocin. (1996) (107)
- Wild-type human p53 activates the human epidermal growth factor receptor promoter. (1994) (105)
- Mucosal vaccination delays or prevents prion infection via an oral route (2005) (98)
- PrPSc-like prion protein peptide inhibits the function of cellular prion protein. (2000) (93)
- Neutralization of human papillomavirus type 11 (HPV-11) by serum from women vaccinated with yeast-derived HPV-11 L1 virus-like particles: correlation with competitive radioimmunoassay titer. (2001) (86)
- Selective oxidation of methionine residues in prion proteins. (1999) (80)
- Down-regulation of MHC class I is a property common to papillomavirus E5 proteins. (2006) (78)
- Anorexia–cachexia and obesity treatment may be two sides of the same coin: role of the TGF-b superfamily cytokine MIC-1/GDF15 (2016) (76)
- Analysis of human papillomavirus types in exophytic condylomata acuminata by hybrid capture and Southern blot techniques (1993) (75)
- Effect of rifampin and bacitracin on nasal carriers of Staphylococcus aureus (1984) (69)
- Macrophage inhibitory cytokine-1 in gestational tissues and maternal serum in normal and pre-eclamptic pregnancy. (2003) (69)
- Cancer-associated human papillomavirus types are selectively increased in the cervix of women in the first trimester of pregnancy. (1996) (67)
- Copper refolding of prion protein. (2000) (65)
- Prion protein expression in muscle cells and toxicity of a prion protein fragment. (1998) (64)
- Taxonomic analysis of the tortoise mycoplasmas Mycoplasma agassizii and Mycoplasma testudinis by 16S rRNA gene sequence comparison. (1995) (64)
- Mycoplasma testudineum sp. nov., from a desert tortoise (Gopherus agassizii) with upper respiratory tract disease. (2004) (63)
- High titers of mucosal and systemic anti-PrP antibodies abrogate oral prion infection in mucosal-vaccinated mice (2008) (62)
- Neutralization of human papillomavirus (HPV) pseudovirions: a novel and efficient approach to detect and characterize HPV neutralizing antibodies. (2000) (60)
- Transmission of human papillomavirus type 11 infection by desquamated cornified cells. (2001) (58)
- Cervical human papillomavirus deoxyribonucleic acid persists throughout pregnancy and decreases in the postpartum period. (1999) (57)
- Cytokine profiling of docetaxel-resistant castration-resistant prostate cancer (2015) (56)
- Control of Leishmania major by a monoclonal alpha beta T cell repertoire. (1998) (56)
- An improved method of purification of transforming growth factor, type beta from platelets. (1988) (55)
- N-terminal 130 amino acids of MDM2 are sufficient to inhibit p53-mediated transcriptional activation. (1995) (55)
- Association of the human papillomavirus type 11 E1()E4 protein with cornified cell envelopes derived from infected genital epithelium. (2000) (53)
- Mycoplasma alligatoris sp. nov., from American alligators. (2001) (52)
- Antibody-based approach to high-volume genotyping for MIC-1 polymorphism. (2002) (51)
- Treatment with the TGF-b superfamily cytokine MIC-1/GDF15 reduces the adiposity and corrects the metabolic dysfunction of mice with diet-induced obesity (2018) (51)
- Microglia and prion disease: a review. (1997) (49)
- PATHOLOGY OF UPPER RESPIRATORY TRACT DISEASE OF GOPHER TORTOISES IN FLORIDA (2000) (48)
- Elevated manganese levels in blood and central nervous system occur before onset of clinical signs in scrapie and bovine spongiform encephalopathy. (2007) (48)
- Mycoplasma agassizii sp. nov., isolated from the upper respiratory tract of the desert tortoise (Gopherus agassizii) and the gopher tortoise (Gopherus polyphemus). (2001) (47)
- Studies on Tanapox virus. (1989) (46)
- Sialidase activity in aerobic vaginitis is equal to levels during bacterial vaginosis. (2013) (46)
- Sequence conservation within the major capsid protein of human papillomavirus (HPV) type 18 and formation of HPV-18 virus-like particles in Saccharomyces cerevisiae. (1996) (46)
- Cell death in prion disease. (1997) (44)
- Plasma MIC-1 correlates with systemic inflammation but is not an independent determinant of nutritional status or survival in oesophago-gastric cancer (2010) (42)
- PATHOLOGY OF EXPERIMENTAL MYCOPLASMOSIS IN AMERICAN ALLIGATORS (2001) (41)
- Identification of a chromosomal determinant of alpha-toxin production in Staphylococcus aureus (1980) (41)
- Altered toxicity of the prion protein peptide PrP106-126 carrying the Ala(117)-->Val mutation. (2000) (41)
- Efficient immunity against Leishmania major in the absence of interleukin-6 (1997) (40)
- Mycoplasma crocodyli sp. nov., a new species from crocodiles. (1997) (39)
- Functional characterization of the C---C chemokine-like molecules encoded by molluscum contagiosum virus types 1 and 2. (1997) (38)
- Human papillomavirus infections of the genital tract. (1990) (38)
- A novel Mycoplasma sp. associated with proliferative tracheitis and pneumonia in a Burmese python (Python molurus bivittatus). (1997) (36)
- Detection of Antibodies to a Pathogenic Mycoplasma in American Alligators (Alligator mississippiensis), Broad-Nosed Caimans (Caiman latirostris), and Siamese Crocodiles (Crocodylus siamensis) (2001) (35)
- Human papillomavirus infection and its association with cervical dysplasia in Ecuadorian women attending a private cancer screening clinic. (2009) (35)
- Identification of human papillomavirus type 11 E4 gene products in human tissue implants from athymic mice. (1988) (34)
- Analysis of bacteriophage phi X174 gene A protein-mediated termination and reinitiation of phi X DNA synthesis. II. Structural characterization of the covalent phi X A protein-DNA complex. (1984) (34)
- Detection of multiple human papillomavirus types in condylomata acuminata from immunosuppressed patients. (1994) (32)
- Spreading Factors of Mycoplasma alligatoris, a Flesh-Eating Mycoplasma (2004) (32)
- Toxicity of novel C-terminal prion protein fragments and peptides harbouring disease-related C-terminal mutations. (2001) (31)
- p53 and SV40 T antigen bind to the same region overlapping the conserved domain of the TATA-binding protein. (1993) (31)
- Cloning of the filamentous hemagglutinin of Bordetella pertussis and its expression in Escherichia coli (1987) (30)
- Growth of molluscum contagiosum virus in a human foreskin xenograft model. (1996) (29)
- Neurotoxicity but not infectivity of prion proteins can be induced reversibly in vitro. (2000) (29)
- Taxonomy of the feline mycoplasmas Mycoplasma felifaucium, Mycoplasma feliminutum, Mycoplasma felis, Mycoplasma gateae, Mycoplasma leocaptivus, Mycoplasma leopharyngis, and Mycoplasma simbae by 16S rRNA gene sequence comparisons. (1995) (29)
- Nucleotide sequence and characterization of human papillomavirus type 83, a novel genital papillomavirus. (1999) (28)
- Human papillomavirus detection and typing in thin prep cervical cytologic specimens comparing the Digene Hybrid Capture II Assay, the Roche Linear Array HPV Genotyping Assay, and the Kurabo GeneSquare Microarray Assay. (2010) (27)
- Formation of multiple complexes between actinomycin D and a DNA hairpin: structural characterization by multinuclear NMR. (1994) (26)
- A critical, invariant chain-independent role for H2-M in antigen presentation. (1998) (25)
- Cytomorphologic correlates of human papillomavirus infection in the "normal" cervicovaginal smear. (1997) (23)
- Copper has differential effect on prion protein with polymorphism of position 129. (2000) (23)
- Abnormalities of cornified cell envelopes isolated from human papillomavirus type 11-infected genital epithelium. (2000) (23)
- Human oncoprotein mdm2 interacts with the tata-binding protein in-vitro and in-vivo. (1995) (23)
- Mycoplasma iguanae sp. nov., from a green iguana (Iguana iguana) with vertebral disease. (2006) (21)
- Low‐level persistence of human papillomavirus 16 DNA in a cohort of closely followed adolescent women (2011) (20)
- Analysis of bacteriophage phi X174 gene A protein-mediated termination and reinitiation of phi X DNA synthesis. I. Characterization of the termination and reinitiation reactions. (1984) (19)
- The human papillomavirus type 11 E1E4 protein is phosphorylated in genital epithelium. (2000) (19)
- The glio-toxic mechanism of alpha-aminoadipic acid on cultured astrocytes. (1998) (19)
- Cephalexin-supplemented Jones-Kendrick charcoal agar for selective isolation of Bordetella pertussis: comparison with previously described media (1983) (18)
- Differential modulation of cellular and viral promoters by p73 and p53. (2001) (18)
- Identification and characterization of a neutralizing monoclonal antibody against botulinum neurotoxin serotype F, following vaccination with active toxin. (1997) (18)
- CD200 is a useful diagnostic marker for identifying atypical chronic lymphocytic leukemia by flow cytometry (2018) (18)
- The intracellular expression pattern of the human papillomavirus type 11 E1--E4 protein correlates with its ability to self associate. (1998) (17)
- A cross-sectional analysis of factors associated with detection of oncogenic human papillomavirus in human immunodeficiency virus-infected and uninfected Kenyan women (2019) (17)
- Molecular cloning and structural analysis of canine gastric H+,K(+)-ATPase. (1993) (16)
- A human papillomavirus related to human papillomavirus MM7/LVX82 produces distinct histological abnormalities in human foreskin implants grown as athymic mouse xenografts. (1998) (16)
- Human papillomavirus type 6: classification of clinical isolates and functional analysis of E2 proteins. (1999) (15)
- International Committee on Systematics of Prokaryotes. Subcommittee on the taxonomy of Mollicutes: Minutes of the meetings, July 15th and 19th 2012, Toulouse, France. (2013) (15)
- Mapping the antigenicity of copper-treated cellular prion protein with the scrapie isoform (2003) (14)
- MIC-1/GDF15 in Barrett's oesophagus and oesophageal adenocarcinoma (2015) (13)
- A Yin-Yang role for metals in prion disease. (2001) (12)
- Factors associated with detection of human papillomavirus E4 and L1 proteins in condylomata acuminata. (1992) (12)
- DNA sequences which support activities of the bacteriophage phi X174 gene A protein. (1983) (12)
- Isolation and characterization of Arthrobacter bacteriophages and their application to phage typing of soil arthrobacters (1978) (12)
- Sequence variation in the extreme 5' end of the human papillomavirus type 6a long control region. (1995) (12)
- Comparison of the Freelite serum free light chain (SFLC) assay with serum and urine electrophoresis/immunofixation and the N Latex FLC assay (2015) (11)
- The human oncoprotein MDM2 uses distinct strategies to inhibit transcriptional activation mediated by the wild-type p53 and its tumor-derived mutants. (2001) (11)
- Cell-type-specific induction of the UL9 gene of HSV-1 by cell signaling pathway. (1994) (11)
- Mycoplasma microti sp. nov., isolated from the respiratory tract of prairie voles (Microtus ochrogaster). (2001) (10)
- Macrophage inhibitory cytokine‐1/growth differentiation factor‐15 as a predictor of colonic neoplasia (2017) (10)
- DNA structures required for phi X174 A-protein-directed initiation and termination of DNA replication. (1983) (10)
- International Committee on Systematics of Prokaryotes Subcommittee on the taxonomy of Mollicutes: Minutes of the closed meeting, 8 July 2018, Portsmouth, New Hampshire, USA. (2019) (9)
- Mapping of the gene encoding the beta-subunit of H+,K(+)-ATPase to human chromosome 13q34 by fluorescence in situ hybridization. (1992) (9)
- Human papillomavirus type 11 E1--E4 and L1 proteins colocalize in the mouse xenograft system at multiple time points. (1995) (9)
- Mycoplasma alligatoris Infection Promotes CD95 (FasR) Expression and Apoptosis of Primary Cardiac Fibroblasts (2005) (9)
- Therapeutics and prion disease: can immunisation or drugs be effective? (2005) (8)
- Lectin-resistant B16 melanoma cells exhibit an altered response to MSH and cholera toxin. (1983) (8)
- Association of human papillomavirus type 11 DNA with squamous cell carcinoma of the tongue. (1996) (8)
- Therapeutics in Alzheimer's and prion diseases. (2001) (7)
- Further evidence for the absence of papillomaviruses from sea turtle fibropapillomas (1999) (6)
- Functional and structural differences between the prion protein from two alleles prnp(a) and prnp(b) of mouse. (2000) (6)
- Genome Annotation of Five Mycoplasma canis Strains (2012) (5)
- Analysis of the promoter sequences of the UL9 gene of herpes simplex virus type 1. (1993) (4)
- Virus-like particles and E1-E4 protein expressed from the human papillomavirus type 11 bicistronic E1-E4-L1 transcript. (1996) (4)
- Construction and characterization of genetically inactivated pertussis toxin. (1991) (4)
- An introduction to computer viruses (1992) (4)
- Isolation of mycoplasmas from prairie voles (Microtus ochrogaster). (1995) (3)
- International Committee on Systematics of Prokaryotes Subcommittee on the taxonomy of Mollicutes: minutes of the meetings (closed and open), 1 and 5 June 2014, Blumenau SC, Brazil. (2014) (3)
- Prion protein Peptide : agents of death for neurons. (2001) (3)
- International Committee on Systematics of ProkaryotesSubcommittee on the taxonomy of Mollicutes (2011) (3)
- Regulation of Prion Protein Expression: A Potential Site for Therapeutic Intervention in the Transmissible Spongiform Encephalopathies (2006) (2)
- Cytokines' profiles to predict chemotherapy outcome in castration-resistant prostate cancer (CRPC). (2011) (2)
- Genome Sequences of Mycoplasma alligatoris A21JP2 T and Mycoplasma crocodyli MP145 T (cid:1) (2011) (2)
- The East Africa Consortium for human papillomavirus and cervical cancer in women living with HIV/AIDS (2022) (1)
- Colocalization of human papillomavirus type 11 E1[symbol: see text]E4 and L1 proteins in human foreskin implants grown in athymic mice. (1994) (1)
- Neurodegenerative Disease and Treatments (2003) (0)
- Scleroderma lung disease: appropriate management. (1997) (0)
- The Lymphoid V(D)J Recombination Activity: Studies of Exogenous Plasmid Substrates in Whole Cells (1989) (0)
- Analysis in vitro of a step in prion-mediated neuro-degenerative disease using prion protein “gene knock-out” mice: A Commentary on the paper (1994) (0)
- A function for the prion protein? (2001) (0)
- Metal Toxicity and Therapeutic Intervention Copper and prion diseases (2002) (0)
- RETROSPECTIVE AUDIT OF THE FREELITE™ SERUM FREE LIGHT CHAIN (SFLC) ASSAY: TESTING PATTERNS, CONCORDANCE WITH SERUM AND URINE ELECTROPHORESIS/IMMUNOFIXATION AND CORRELATION WITH THE N LATEX FLC ASSAY (2015) (0)
- Identification of candidate biomarkers of therapeutic response to docetaxel in hormone-refractory prostate cancer by proteomic profiling. (2009) (0)
- Analysis of the phiX174 gene A protein using in vitro DNA replication systems. (1983) (0)
- P0098 : Macrophage inhibitory cytokine-1 (MIC-1) is associated with degree of liver fibrosis in HCV-related liver disease - The MILC Study (2015) (0)
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