David Siderovski
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Computer Science
David Siderovski's Degrees
- PhD Computer Science Stanford University
- Masters Computer Science University of California, Berkeley
- Bachelors Computer Science University of California, Berkeley
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Why Is David Siderovski Influential?
(Suggest an Edit or Addition)According to Wikipedia, David Siderovski is a North American pharmacologist. Since March 2020, Siderovski has been Chair of the HSC Department of Pharmacology & Neuroscience at the University of North Texas Health Science Center. From 2012 to 2019, he was the E.J. Van Liere Medicine Professor and Chair of Physiology, Pharmacology & Neuroscience for the West Virginia University School of Medicine.
David Siderovski's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Molecular characterization of mitochondrial apoptosis-inducing factor (1999) (4165)
- Negative Regulation of PKB/Akt-Dependent Cell Survival by the Tumor Suppressor PTEN (1998) (2539)
- 5'-Capping enzymes are targeted to pre-mRNA by binding to the phosphorylated carboxy-terminal domain of RNA polymerase II. (1997) (561)
- G-protein signaling: back to the future (2005) (486)
- Regulators of G-Protein signalling as new central nervous system drug targets (2002) (410)
- The GAPs, GEFs, and GDIs of heterotrimeric G-protein alpha subunits (2005) (408)
- Regulator of G-protein signaling-2 mediates vascular smooth muscle relaxation and blood pressure (2003) (395)
- Tiam1 mediates Ras activation of Rac by a PI(3)K-independent mechanism (2002) (339)
- A Seven-Transmembrane RGS Protein That Modulates Plant Cell Proliferation (2003) (310)
- Dynamic Regulation of RGS2 Suggests a Novel Mechanism in G-Protein Signaling and Neuronal Plasticity (1998) (309)
- Regulation of T cell activation, anxiety, and male aggression by RGS2. (2000) (289)
- Structural and evolutionary division of phosphotyrosine binding (PTB) domains. (2005) (263)
- Translation of Polarity Cues into Asymmetric Spindle Positioning in Caenorhabditis elegans Embryos (2003) (255)
- Molecular cloning of LSIRF, a lymphoid-specific member of the interferon regulatory factor family that binds the interferon-stimulated response element (ISRE). (1995) (250)
- Structural determinants for GoLoco-induced inhibition of nucleotide release by Gα subunits (2002) (249)
- A G protein γ subunit-like domain shared between RGS11 and other RGS proteins specifies binding to Gβ5 subunits (1998) (248)
- The mitochondrial proteins NLRX1 and TUFM form a complex that regulates type I interferon and autophagy. (2012) (241)
- The telomerase reverse transcriptase is limiting and necessary for telomerase function in vivo (2000) (239)
- Regulators of G-Protein Signaling and Their Gα Substrates: Promises and Challenges in Their Use as Drug Discovery Targets (2011) (232)
- A crystallographic view of interactions between Dbs and Cdc42: PH domain‐assisted guanine nucleotide exchange (2002) (228)
- GTPase Activating Specificity of RGS12 and Binding Specificity of an Alternatively Spliced PDZ (PSD-95/Dlg/ZO-1) Domain* (1998) (225)
- Structural basis for the selective activation of Rho GTPases by Dbl exchange factors (2002) (223)
- A new family of regulators of G-protein-coupled receptors? (1996) (221)
- RGS12 and RGS14 GoLoco Motifs Are GαiInteraction Sites with Guanine Nucleotide Dissociation Inhibitor Activity* (2001) (218)
- Return of the GDI: the GoLoco motif in cell division. (2004) (199)
- Regulator of G protein signaling 2 mediates cardiac compensation to pressure overload and antihypertrophic effects of PDE5 inhibition in mice. (2009) (194)
- GTPase acceleration as the rate-limiting step in Arabidopsis G protein-coupled sugar signaling (2007) (193)
- RIC-8 Is Required for GPR-1/2-Dependent Gα Function during Asymmetric Division of C. elegans Embryos (2004) (192)
- LGN regulates mitotic spindle orientation during epithelial morphogenesis (2010) (183)
- Leukemia-Associated Rho Guanine Nucleotide Exchange Factor Promotes Gαq-Coupled Activation of RhoA (2002) (183)
- The GoLoco motif: a Galphai/o binding motif and potential guanine-nucleotide exchange factor. (1999) (172)
- Structural diversity in the RGS domain and its interaction with heterotrimeric G protein α-subunits (2008) (170)
- HIV-1 Tat directly interacts with the interferon-induced, double-stranded RNA-dependent kinase, PKR. (1995) (158)
- Activator of G protein signaling 3 is a guanine dissociation inhibitor for Galpha i subunits. (2000) (158)
- Receptor-Mediated Activation of Heterotrimeric G-Proteins: Current Structural Insights (2007) (151)
- Tyrosine-kinase-dependent recruitment of RGS12 to the N-type calcium channel (2000) (148)
- Rgs1 regulates multiple Gα subunits in Magnaporthe pathogenesis, asexual growth and thigmotropism (2007) (142)
- Mammalian Inscuteable Regulates Spindle Orientation and Cell Fate in the Developing Retina (2005) (141)
- Receptor-selective Effects of Endogenous RGS3 and RGS5 to Regulate Mitogen-activated Protein Kinase Activation in Rat Vascular Smooth Muscle Cells* (2002) (128)
- Ric-8 controls Drosophila neural progenitor asymmetric division by regulating heterotrimeric G proteins (2005) (125)
- A human gene encoding a putative basic helix-loop-helix phosphoprotein whose mRNA increases rapidly in cycloheximide-treated blood mononuclear cells. (1994) (121)
- Gγ-like (GGL) domains: New frontiers in G-protein signaling and β-propeller scaffolding (2001) (118)
- Molecular cloning and expression analysis of rat Rgs12 and Rgs14. (1997) (117)
- PB1 Domain Interaction of p62/Sequestosome 1 and MEKK3 Regulates NF-κB Activation* (2009) (116)
- Comment on "A G Protein–Coupled Receptor Is a Plasma Membrane Receptor for the Plant Hormone Abscisic Acid" (2007) (114)
- Fidelity of G protein β-subunit association by the G protein γ-subunit-like domains of RGS6, RGS7, and RGS11 (1999) (114)
- Clathrin Adaptor AP2 Regulates Thrombin Receptor Constitutive Internalization and Endothelial Cell Resensitization (2006) (112)
- Whither goest the RGS proteins? (1999) (111)
- Crystal structure of the multifunctional Gβ5–RGS9 complex (2008) (109)
- Structure-based protocol for identifying mutations that enhance protein-protein binding affinities. (2007) (102)
- Activation of Phospholipase C-ε by Heterotrimeric G Protein βγ-Subunits* (2001) (100)
- Chronic Olanzapine Treatment Causes Differential Expression of Genes in Frontal Cortex of Rats as Revealed by DNA Microarray Technique (2006) (98)
- Quantitative Analysis of the Effect of Phosphoinositide Interactions on the Function of Dbl Family Proteins* (2001) (89)
- A G protein gamma subunit-like domain shared between RGS11 and other RGS proteins specifies binding to Gbeta5 subunits. (1998) (83)
- Gβγ Isoforms Selectively Rescue Plasma Membrane Localization and Palmitoylation of Mutant Gαs and Gαq * (2001) (82)
- Exome Sequencing in 53 Sporadic Cases of Schizophrenia Identifies 18 Putative Candidate Genes (2014) (81)
- Cloning of human lymphocyte-specific interferon regulatory factor (hLSIRF/hIRF4) and mapping of the gene to 6p23-p25. (1996) (81)
- β2-Adrenoceptor agonist-induced RGS2 expression is a genomic mechanism of bronchoprotection that is enhanced by glucocorticoids (2011) (80)
- Cortical localization of the Gα protein GPA-16 requires RIC-8 function during C. elegans asymmetric cell division (2005) (80)
- Telomerase-Associated Protein TEP1 Is Not Essential for Telomerase Activity or Telomere Length Maintenance In Vivo (2000) (79)
- A set of human putative lymphocyte G0/G1 switch genes includes genes homologous to rodent cytokine and zinc finger protein-encoding genes. (1990) (78)
- Selective role for RGS12 as a Ras/Raf/MEK scaffold in nerve growth factor‐mediated differentiation (2007) (78)
- Structure of Galpha(i1) bound to a GDP-selective peptide provides insight into guanine nucleotide exchange. (2005) (76)
- Regulators of G-protein Signaling accelerate GPCR signaling kinetics and govern sensitivity solely by accelerating GTPase activity (2010) (76)
- RGS14 is a mitotic spindle protein essential from the first division of the mammalian zygote. (2004) (67)
- Structural Determinants of G-protein α Subunit Selectivity by Regulator of G-protein Signaling 2 (RGS2)* (2009) (65)
- Guanine nucleotide dissociation inhibitor activity of the triple GoLoco motif protein G18: alanine-to-aspartate mutation restores function to an inactive second GoLoco motif. (2004) (65)
- Genome-Scale Analysis Reveals Sst2 as the Principal Regulator of Mating Pheromone Signaling in the Yeast Saccharomyces cerevisiae (2006) (65)
- D2 dopamine receptor activation of potassium channels is selectively decoupled by Gαi‐specific GoLoco motif peptides (2005) (62)
- Selective Regulation of N-Type Ca Channels by Different Combinations of G-Protein β/γ Subunits and RGS Proteins (2000) (62)
- Dynamic regulation of mammalian numb by G protein-coupled receptors and protein kinase C activation: Structural determinants of numb association with the cortical membrane. (2006) (62)
- Gα12/13- and Rho-Dependent Activation of Phospholipase C-ϵ by Lysophosphatidic Acid and Thrombin Receptors (2006) (58)
- The G betagamma dimer as a novel source of selectivity in G-protein signaling: GGL-ing at convention. (2004) (55)
- The RGS protein inhibitor CCG-4986 is a covalent modifier of the RGS4 Galpha-interaction face. (2007) (55)
- RGS12 Interacts with the SNARE-binding Region of the Cav2.2 Calcium Channel* (2005) (53)
- High-affinity immobilization of proteins using biotin- and GST-based coupling strategies. (2010) (52)
- Functional relevance of the disulfide‐linked complex of the N‐terminal PDZ domain of InaD with NorpA (2001) (48)
- Differential expression of a basic helix-loop-helix phosphoprotein gene, G0S8, in acute leukemia and localization to human chromosome 1q31. (1995) (47)
- A direct fluorescence-based assay for RGS domain GTPase accelerating activity. (2005) (46)
- A capture coupling method for the covalent immobilization of hexahistidine tagged proteins for surface plasmon resonance. (2010) (46)
- Cloning of a retinally abundant regulator of G-protein signaling (RGS-r/RGS16): genomic structure and chromosomal localization of the human gene. (1998) (45)
- G protein signaling in the parasite Entamoeba histolytica (2013) (45)
- Purification and in vitro functional analysis of the Arabidopsis thaliana regulator of G-protein signaling-1. (2004) (44)
- Established and emerging fluorescence-based assays for G-protein function: Ras-superfamily GTPases. (2003) (44)
- Computational design of the sequence and structure of a protein-binding peptide. (2011) (44)
- Regulator of G-Protein Signaling 14 (RGS14) Is a Selective H-Ras Effector (2009) (43)
- Induction of Regulator of G-Protein Signaling 2 Expression by Long-Acting β2-Adrenoceptor Agonists and Glucocorticoids in Human Airway Epithelial Cells (2014) (43)
- The effect of RGS12 on PDGFbeta receptor signalling to p42/p44 mitogen activated protein kinase in mammalian cells. (2006) (42)
- Cooperative interaction between the DNA-binding domains of PU.1 and IRF4. (1998) (42)
- A point mutation to Galphai selectively blocks GoLoco motif binding: direct evidence for Galpha.GoLoco complexes in mitotic spindle dynamics. (2008) (41)
- Ggamma-like (GGL) domains: new frontiers in G-protein signaling and beta-propeller scaffolding. (2001) (41)
- Identification of a human LIM-Hox gene, hLH-2, aberrantly expressed in chronic myelogenous leukaemia and located on 9q33-34.1. (1996) (40)
- Structural basis for nucleotide exchange on Gαi subunits and receptor coupling specificity (2007) (40)
- The GoLoco motif: heralding a new tango between G protein signaling and cell division. (2002) (38)
- Gα selectivity and inhibitor function of the multiple GoLoco motif protein GPSM2/LGN (2005) (37)
- Two Gα i1 Rate-Modifying Mutations Act in Concert to Allow Receptor-Independent, Steady-State Measurements of RGS Protein Activity (2009) (36)
- RGS14 is a Microtubule-Associated Protein (2005) (35)
- Molecular cloning of regulators of G-protein signaling family members and characterization of binding specificity of RGS12 PDZ domain. (2002) (35)
- Inhibition of Dopamine Transporter Activity by G Protein βγ Subunits (2013) (34)
- Preclinical Testing of Nalfurafine as an Opioid-sparing Adjuvant that Potentiates Analgesia by the Mu Opioid Receptor-targeting Agonist Morphine (2019) (34)
- Established and emerging fluorescence-based assays for G-protein function: heterotrimeric G-protein alpha subunits and regulator of G-protein signaling (RGS) proteins. (2003) (34)
- Minimal determinants for binding activated G alpha from the structure of a G alpha(i1)-peptide dimer. (2006) (33)
- Regulation of T cell activation , anxiety , and male aggression by RGS 2 (2000) (33)
- Fidelity of G protein beta-subunit association by the G protein gamma-subunit-like domains of RGS6, RGS7, and RGS11. (1999) (33)
- Application of RGS box proteins to evaluate G-protein selectivity in receptor-promoted signaling. (2004) (32)
- Gβ Association and Effector Interaction Selectivities of the Divergent Gγ Subunit Gγ13 * (2001) (32)
- Regulator of G-protein Signaling-21 (RGS21) Is an Inhibitor of Bitter Gustatory Signaling Found in Lingual and Airway Epithelia* (2012) (29)
- A high throughput fluorescence polarization assay for inhibitors of the GoLoco motif/G-alpha interaction. (2008) (28)
- Covalent immobilization of histidine-tagged proteins for surface plasmon resonance. (2006) (28)
- G-protein signaling modulator-3, a gene linked to autoimmune diseases, regulates monocyte function and its deficiency protects from inflammatory arthritis. (2013) (28)
- Gbeta gamma isoforms selectively rescue plasma membrane localization and palmitoylation of mutant Galphas and Galphaq. (2001) (27)
- A Non-Canonical Function of Gβ as a Subunit of E3 Ligase in Targeting GRK2 Ubiquitylation. (2015) (27)
- A sweet cycle for Arabidopsis G-proteins (2008) (27)
- A P-loop Mutation in Gα Subunits Prevents Transition to the Active State: Implications for G-protein Signaling in Fungal Pathogenesis (2012) (27)
- G-protein alpha subunit interaction and guanine nucleotide dissociation inhibitor activity of the dual GoLoco motif protein PCP-2 (Purkinje cell protein-2). (2006) (27)
- Activation of phospholipase C-epsilon by heterotrimeric G protein betagamma-subunits. (2001) (27)
- Integrating energy calculations with functional assays to decipher the specificity of G-protein inactivation by RGS proteins (2011) (27)
- G Protein Signaling Modulator-3 Inhibits the Inflammasome Activity of NLRP3* (2014) (26)
- Regulator of G protein signaling 2 mediates cardiac compensation to pressure overload and antihypertrophic effects of PDE 5 inhibition in mice (2009) (26)
- G protein‐coupled receptor kinase‐3‐deficient mice exhibit WHIM syndrome features and attenuated inflammatory responses (2013) (25)
- Heterotrimeric G-protein Signaling Is Critical to Pathogenic Processes in Entamoeba histolytica (2012) (25)
- Helix dipole movement and conformational variability contribute to allosteric GDP release in Galphai subunits. (2009) (24)
- Protective Roles for RGS2 in a Mouse Model of House Dust Mite-Induced Airway Inflammation (2017) (24)
- Galpha12/13- and rho-dependent activation of phospholipase C-epsilon by lysophosphatidic acid and thrombin receptors. (2006) (23)
- Modulating platelet reactivity through control of RGS18 availability. (2015) (23)
- Novel behavioral assays of spontaneous and precipitated THC withdrawal in mice. (2018) (21)
- Single Nucleotide Polymorphisms in Chemosensory Pathway Genes GNB3, TAS2R19, and TAS2R38 Are Associated with Chronic Rhinosinusitis (2019) (21)
- Role of the pleckstrin homology domain in intersectin-L Dbl homology domain activation of Cdc42 and signaling. (2003) (21)
- Fluorescence-based assays for RGS box function. (2004) (20)
- Integrating energy calculations with functional assays to decipher the specificity of G protein – RGS protein interactions (2011) (19)
- Differential expression of regulator of G‐protein signaling R12 subfamily members during mouse development (2005) (19)
- Role of RGS12 in the differential regulation of kappa opioid receptor-dependent signaling and behavior (2019) (18)
- Structural Determinants of Affinity Enhancement between GoLoco Motifs and G-Protein α Subunit Mutants* (2010) (18)
- Differential G-alpha interaction capacities of the GoLoco motifs in Rap GTPase activating proteins. (2007) (18)
- Regulators of G-protein signaling (2004) (18)
- A bifunctional Gαi/Gαs modulatory peptide that attenuates adenylyl cyclase activity (2005) (18)
- Selective regulation of N-type Ca channels by different combinations of G-protein beta/gamma subunits and RGS proteins. (2000) (17)
- Unique Structural and Nucleotide Exchange Features of the Rho1 GTPase of Entamoeba histolytica* (2011) (17)
- Regulator of G protein signaling-12 modulates the dopamine transporter in ventral striatum and locomotor responses to psychostimulants (2018) (17)
- Regulation of Protease-activated Receptor 1 Signaling by the Adaptor Protein Complex 2 and R4 Subfamily of Regulator of G Protein Signaling Proteins* (2013) (16)
- Entamoeba histolytica Rho1 regulates actin polymerization through a divergent, diaphanous-related formin. (2012) (16)
- RNA interference screen for RGS protein specificity at muscarinic and protease-activated receptors reveals bidirectional modulation of signaling. (2010) (16)
- G-protein Signaling Modulator-3 Regulates Heterotrimeric G-protein Dynamics through Dual Association with Gβ and Gαi Protein Subunits* (2011) (16)
- G protein signaling modulator-3: a leukocyte regulator of inflammation in health and disease. (2014) (16)
- G alpha selectivity and inhibitor function of the multiple GoLoco motif protein GPSM2/LGN. (2005) (16)
- G beta association and effector interaction selectivities of the divergent G gamma subunit G gamma(13). (2001) (16)
- Structural Determinants Underlying the Temperature-sensitive Nature of a Gα Mutant in Asymmetric Cell Division of Caenorhabditis elegans* (2008) (15)
- Chemerin-activated functions of CMKLR1 are regulated by G protein-coupled receptor kinase 6 (GRK6) and β-arrestin 2 in inflammatory macrophages. (2019) (15)
- Random mutagenesis of the human immunodeficiency virus type-1 trans-activator of transcription (HIV-1 Tat). (1992) (14)
- Structural Determinants of Ubiquitin Conjugation in Entamoeba histolytica* (2012) (13)
- The R6A-1 peptide binds to switch II of Galphai1 but is not a GDP-dissociation inhibitor. (2006) (13)
- PB 1 Domain Interaction of p 62 / Sequestosome 1 and MEKK 3 Regulates NF-B Activation * (2009) (12)
- Potential for Kappa-Opioid Receptor Agonists to Engineer Nonaddictive Analgesics: A Narrative Review. (2020) (12)
- A role for Regulator of G protein Signaling-12 (RGS12) in the balance between myoblast proliferation and differentiation (2019) (11)
- Purification and in vitro functional analyses of RGS12 and RGS14 GoLoco motif peptides. (2004) (11)
- Evaluating Modulators of “Regulator of G‐protein Signaling” (RGS) Proteins (2012) (11)
- Regulation of the Subcellular Localization of the G-protein Subunit Regulator GPSM3 through Direct Association with 14-3-3 Protein* (2012) (10)
- State-selective binding peptides for heterotrimeric G-protein subunits: novel tools for investigating G-protein signaling dynamics. (2008) (9)
- Review G-protein signaling: back to the future (2005) (9)
- Fidelity of G protein b-subunit association by the G protein g-subunit-like domains of RGS 6 , RGS 7 , and RGS 11 (1999) (9)
- Assays of complex formation between RGS protein Gγ subunit-like domains and Gβ subunits (2002) (8)
- Structural Determinants of RGS‐RhoGEF Signaling Critical to Entamoeba histolytica Pathogenesis (2013) (8)
- RAMHA: a PC-based Monte-Carlo simulation of random saturation mutagenesis. (1993) (8)
- A Point Mutation to Gαi Selectively Blocks GoLoco Motif Binding (2008) (8)
- Entamoeba histolytica RacC Selectively Engages p21-Activated Kinase Effectors (2014) (8)
- RGS21, a regulator of taste and mucociliary clearance? (2013) (7)
- A bifunctional Galphai/Galphas modulatory peptide that attenuates adenylyl cyclase activity. (2005) (7)
- Importance of the autosomal recessive retinitis pigmentosa locus on 1q31-q32.1 (RP12) and mutation analysis of the candidate gene RGS16 (RGS-r) (2000) (7)
- Correction to Helix Dipole Movement and Conformational Variability Contribute to Allosteric GDP Release in Gαi Subunits (2010) (6)
- Erratum: Regulators of G-protein Signaling accelerate GPCR signaling kinetics and govern sensitivity solely by accelerating GTPase activity (Proceedings of the National Academy of Sciences of the United States of America (2010) 107, 15, (7066-7071) DOI: 10.1073/pnas.0912934107) (2012) (6)
- Analysis of interactions between regulator of G-protein signaling-14 and microtubules. (2004) (5)
- Development of Full Sweet, Umami, and Bitter Taste Responsiveness Requires Regulator of G protein Signaling-21 (RGS21) (2018) (5)
- Large G-Proteins (2008) (4)
- Four single nucleotide polymorphisms in genes involved in neuronal signaling are associated with Opioid Use Disorder in West Virginia. (2019) (4)
- CHAPTER 225 – The RGS Protein Superfamily (2003) (4)
- Structures of G [alpha [superscript i1]] Bound to a GDP-Selective Peptide Provides Insight into Guanine Nucleotide Exchange (2010) (3)
- Structural Determinants Underlying the Temperature-sensitiveNature of a G Mutant in (2008) (2)
- A homogeneous method to measure nucleotide exchange by α-subunits of heterotrimeric G-proteins using fluorescence polarization. (2010) (2)
- Modulation of G-Protein Coupled Receptors (2011) (2)
- Correction: Exome Sequencing in 53 Sporadic Cases of Schizophrenia Identifies 18 Putative Candidate Genes (2015) (2)
- Erratum: Cloning of a retinally abundant regulator of G-protein signaling (RGS-r/RGS16): Genomic structure and chromosomal localization of the human gene (Gene (1998) 206 (247-253) PII: SO378111997005933) (1998) (2)
- The stability of tastant detection by mouse lingual chemosensory tissue requires Regulator of G protein Signaling-21 (RGS21). (2021) (2)
- Self-activating G protein α subunits engage seven-transmembrane regulator of G protein signaling (RGS) proteins and a Rho guanine nucleotide exchange factor effector in the amoeba Naegleria fowleri (2022) (1)
- Erratum: Differential expression of a basic helix-loop-helix phosphoprotein gene, GOS8, in acute leukemia and localization to human chromosome 1q31 (Leukemia (1995) 9 (1291-1298)) (1995) (1)
- Assays of complex formation between RGS protein G gamma subunit-like domains and G beta subunits. (2002) (1)
- Faculty Opinions recommendation of Post-marketing surveillance study of the safety and efficacy of nalfurafine hydrochloride (Remitch® capsules 2.5 μg) in 3,762 hemodialysis patients with intractable pruritus. (2018) (1)
- Advances in Combinatorial Chemistry & High Throughput Screening (2013) (1)
- Genetic deletion of Rgs12 in mice affects serotonin transporter expression and function in vivo and ex vivo (2020) (1)
- The superfamily of "regulator of g-protein signaling" (rgs) proteins (2010) (1)
- G-Protein Activation State-Selective Binding Peptides as New Tools for Probing Heterotrimeric G-protein Subunit Signaling Dynamics (2013) (0)
- Mechanism underlying the critical contribution of a switch II residue in a heterotrimeric G-protein alpha subunit during C. elegans asymmetric cell division (2008) (0)
- A Homogeneous Platform to Discover Inhibitors of the GoLoco Motif/G-alpha Interaction (2013) (0)
- Review Article G protein signaling modulator-3: a leukocyte regulator of inflammation in health and disease (2014) (0)
- G Protein Coupled Receptor Kinase 3 (GRK3) - Deficient T Cells Demonstrate Enhanced Migration To CXCL12 And CX3CL1 (2011) (0)
- G (cid:1) Association and Effector Interaction Selectivities of the Divergent G (cid:2) Subunit G (cid:2) 13 * (2001) (0)
- GPCR high throughput screening (part 1). (2008) (0)
- REGULATION OF RGS5 GAP ACTIVITY BY THE GOLOCO MOTIF CONTAINING PROTEIN G18/AGS4 (2011) (0)
- Crystal structure of EhRho1 bound to GDP and Magnesium (2011) (0)
- Activation of Phospholipase C- (cid:1) by Heterotrimeric G Protein (cid:2)(cid:3) -Subunits* (2001) (0)
- Correction for Regulators of G-protein Signaling accelerate GPCR signaling kinetics and govern sensitivity solely by accelerating GTPase activity (2012) (0)
- Crystal structure of the G202A mutant of human G-alpha-i1 (2012) (0)
- G-protein Signaling Modulator-3 Regulates Heterotrimeric G-protein Dynamics through Dual Association with G (cid:1) and G (cid:2) i Protein Subunits (2020) (0)
- Crystal Structure Of Human G alpha i1 Bound To A Designed Helical Peptide Derived From The Goloco Motif Of RGS14 (2011) (0)
- Crystal Structure of the DH/PH Fragment of Murine Dbs in Complex with the Placental Isoform of Human Cdc42 (2002) (0)
- Crystal Structure of Human G[alpha]i1 Bound to the GoLoco Motif of RGS14 (2002) (0)
- Crystal structure of E. histolytica Formin1 bound to EhRho1-GTPgammaS (2012) (0)
- The telomerase reverse transcriptase is limiting and necessary for telomerase function in vivo (2001) (0)
- Human Immunodeficiency Virus Type-1 Trans-activator of Transcription (HIV-1 Tat), Random Mutagenesis and Interaction with PKR (1997) (0)
- Localization of Regulator of G-Protein Signaling 11 (RGS11) in Rat and Monkey Photoreceptors and RPE (2003) (0)
- GPSM3 gene variant protects against the development of Rheumatoid Arthritis (2016) (0)
- Faculty Opinions recommendation of The coding of valence and identity in the mammalian taste system. (2019) (0)
- Crystal Structure of the G-protein Betagamma Subunit Bound to a C-terminal Region of the PTH1 Parathyroid Hormone Receptor (2008) (0)
- Structure of activated G-alpha-i1 bound to a nucleotide-state-selective peptide: Minimal determinants for recognizing the active form of a G protein alpha subunit (2006) (0)
- Structural studies of RGS9/Gβ5 (2008) (0)
- Crystal Structure of the N-terminal PDZ domain of InaD in complex with a NorpA C-terminal peptide (2001) (0)
- Crystal structure of the AMF-bound conformation of a G-alpha-i1 mutant with enhanced GTPase activity (2008) (0)
- UNCMD-PhD Newsletter (2011) (0)
- the Inflammasome Activity of NLRP 3 G Protein Signaling Modulator-3 Inhibits Immunology : (2014) (0)
- Faculty Opinions recommendation of RGS14 regulates the lifetime of Gα-GTP signaling but does not prolong Gβγ signaling following receptor activation in live cells. (2016) (0)
- Editorial [Hot Topic: GPCR High Throughput Screening (Part 1) (Guest Editors: David P. Siderovski and Francis S. Willard)] (2008) (0)
- REGULATION OF CANNABINOID RECEPTOR SIGNALING BY RGS (REGULATORS OF G‐PROTEIN SIGNALING) PROTEINS: A NEW PARADIGM FOR MODULATING CB1 AND CB2 RECEPTOR‐MEDIATED SIGNALOSOME (2012) (0)
- Structural studies of RGS9/G{beta}5 (2008) (0)
- Crystal structure of ubiquitin from Entamoeba histolytica to 1.35 Angstrom (2012) (0)
- Combinatorial Chemistry & High Throughput Screening: Editorial (2008) (0)
- The Biased Kappa Opioid Receptor Agonist Nalfurafine Reduces the Reinforcing Properties of Oxycodone and Enhances Oxycodone‐Induced Spinal Anti‐Nociception (2020) (0)
- Crystal structure of E. histolytica RacC bound to the EhPAK4 PBD (2014) (0)
- Structure of a G-alpha-i1 mutant with enhanced affinity for the RGS14 GoLoco motif. (2010) (0)
- Crystal structure of an RGS-RhoGEF from Entamoeba histolytica (2013) (0)
- Crystal Structure of the Dbl and Pleckstrin homology domains of Dbs in complex with RhoA (2002) (0)
- A Galpha-i1 P-loop mutation prevents transition to the activated state (2012) (0)
- Regulation of G protein alpha subunits by natural proteins and artificial peptides (2006) (0)
- REGULATION OF THE SUBCELLULAR LOCALIZATION OF THE G-PROTEIN SUBUNIT REGULATOR GPSM 3 THROUGH DIRECT ASSOCIATION WITH 14-3-3 (2012) (0)
- Crystal structure of EhUbc5, a ubiquitin conjugating enzyme from Entamoeba histolytica (2012) (0)
- Corrigendum: Regulator of G-protein signaling-2 mediates vascular smooth muscle relaxation and blood pressure (2004) (0)
- Cortical localization of the G (cid:2)(cid:2) protein GPA-16 requires RIC-8 function during C. elegans asymmetric cell division (2005) (0)
- Crystal structure of EhRho1 bound to a GTP analog and Magnesium (2011) (0)
- The multifunctional nature of Gbeta5/RGS9 revealed from its crystal structure (2008) (0)
- A Galpha P-loop mutation prevents transition to the activated state: G42R bound to RGS14 GoLoco (2012) (0)
- Crystal structure of ubiquitin from Entamoeba histolytica to 2.15 Angstrom (2012) (0)
- Immunologic Phenotype Of GRK3-null Mice At Baseline And In Inflammatory Disease (2012) (0)
- Induction Of Regulator Of G-Protein Signalling (RGS)2 By Long-Acting ²2-Adrenoceptor Agonists Is A Novel Genomic Mechanism Of Bronchoprotection That Is Enhanced By Glucocorticoids (2011) (0)
- Faculty Opinions recommendation of Serotonin transporter inhibition and 5-HT2C receptor activation drive loss of cocaine-induced locomotor activation in DAT Val559 mice. (2019) (0)
- Crystal structure of a heterotrimeric G-Protein subunit from entamoeba histolytica, EHG-ALPHA-1 (2012) (0)
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