David Sidransky

Q: What Schools Are Affiliated With David Sidransky

David Sidransky is affiliated with the following schools: Weizmann Institute of Science, University of Ulsan College of Medicine, Istanbul University, University of Bari, Johns Hopkins University, University of Virginia

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David Sidransky

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#1124

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Philosophy

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David Sidransky's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

p53 mutations in human cancers. (1991) (8282)
A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer. (1998) (4146)
Participation of p53 protein in the cellular response to DNA damage. (1991) (3972)
Evidence for a causal association between human papillomavirus and a subset of head and neck cancers. (2000) (2990)
5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers (1995) (2108)
Exome Sequencing of Head and Neck Squamous Cell Carcinoma Reveals Inactivating Mutations in NOTCH1 (2011) (1652)
Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers. (1995) (1490)
Detection of aberrant promoter hypermethylation of tumor suppressor genes in serum DNA from non-small cell lung cancer patients. (1999) (982)
Dysfunctional KEAP1–NRF2 Interaction in Non-Small-Cell Lung Cancer (2006) (931)
BRAF mutation predicts a poorer clinical prognosis for papillary thyroid cancer. (2005) (929)
Identification of p53 gene mutations in bladder cancers and urine samples. (1991) (865)
Mutations in BRAF and KRAS characterize the development of low-grade ovarian serous carcinoma. (2003) (842)
Facile detection of mitochondrial DNA mutations in tumors and bodily fluids. (2000) (809)
BRAF mutation in papillary thyroid carcinoma. (2003) (796)
Association between BRAF V600E mutation and mortality in patients with papillary thyroid cancer. (2013) (784)
Frequent inactivation of PTEN/MMAC1 in primary prostate cancer. (1997) (759)
Molecular assessment of histopathological staging in squamous-cell carcinoma of the head and neck. (1995) (757)
Head and neck cancer. (2001) (752)
DPC4 gene in various tumor types. (1996) (745)
Clonal expansion of p53 mutant cells is associated with brain tumour progression (1992) (742)
Identification of ras oncogene mutations in the stool of patients with curable colorectal tumors. (1992) (741)
Poster 7: A Genetic Progression Model for Head and Neck Cancer: Implications for Field Cancerization (1996) (741)
Frequency of homozygous deletion at p16/CDKN2 in primary human tumours (1995) (703)
TP53 mutations and survival in squamous-cell carcinoma of the head and neck. (2007) (694)
Microsatellite alterations in serum DNA of head and neck cancer patients (1996) (688)
Role of the p16 tumor suppressor gene in cancer. (1998) (681)
Emerging molecular markers of cancer (2002) (653)
Association between cigarette smoking and mutation of the p53 gene in squamous-cell carcinoma of the head and neck. (1995) (652)
The incidence of p53 mutations increases with progression of head and neck cancer. (1993) (640)
High frequency of p16 (CDKN2/MTS-1/INK4A) inactivation in head and neck squamous cell carcinoma. (1996) (616)
Inactivation of LKB1/STK11 is a common event in adenocarcinomas of the lung. (2002) (605)
Pathology & Genetics Head and Neck Tumours (2007) (587)
Analysis of adenomatous polyposis coli promoter hypermethylation in human cancer. (2000) (574)
p53 Mutation and MDM2 amplification in human soft tissue sarcomas. (1993) (563)
Gene promoter hypermethylation in tumors and serum of head and neck cancer patients. (2000) (556)
Somatic mutations of PTEN in glioblastoma multiforme. (1997) (554)
Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesis. (2000) (549)
Mitochondrial DNA mutations in human cancer (2006) (543)
AIS is an oncogene amplified in squamous cell carcinoma. (2000) (539)
Clonal origin of bladder cancer. (1992) (521)
Interfocal heterogeneity of PTEN/MMAC1 gene alterations in multiple metastatic prostate cancer tissues. (1998) (492)
Rates of p16 (MTS1) mutations in primary tumors with 9p loss. (1994) (483)
p16(MTS-1/CDKN2/INK4a) in cancer progression. (2001) (480)
Microsatellite alterations as clonal markers for the detection of human cancer. (1994) (474)
Cigarette smoking is strongly associated with mutation of the K‐ras gene in patients with primary adenocarcinoma of the lung (2001) (420)
Detection of oncogene mutations in sputum precedes diagnosis of lung cancer. (1994) (415)
A Pilot Clinical Study of Treatment Guided by Personalized Tumorgrafts in Patients with Advanced Cancer (2011) (387)
Nucleic acid-based methods for the detection of cancer. (1997) (387)
BCR-ABL-mediated inhibition of apoptosis with delay of G2/M transition after DNA damage: a mechanism of resistance to multiple anticancer agents. (1995) (386)
Promoter hypermethylation patterns of p16, O6-methylguanine-DNA-methyltransferase, and death-associated protein kinase in tumors and saliva of head and neck cancer patients. (2001) (384)
Allelotype of head and neck squamous cell carcinoma. (1994) (383)
Molecular Detection of Primary Bladder Cancer by Microsatellite Analysis (1996) (382)
Frequent loss of chromosome 9p21-22 early in head and neck cancer progression. (1994) (381)
Hypermethylated APC DNA in plasma and prognosis of patients with esophageal adenocarcinoma. (2000) (380)
Pharmacologic unmasking of epigenetically silenced tumor suppressor genes in esophageal squamous cell carcinoma. (2002) (352)
Detecting colorectal cancer in stool with the use of multiple genetic targets. (2001) (347)
A novel p16INK4A transcript. (1995) (343)
Detection of somatic mutations and HPV in the saliva and plasma of patients with head and neck squamous cell carcinomas (2015) (343)
Molecular detection of tumor cells in bronchoalveolar lavage fluid from patients with early stage lung cancer. (1999) (343)
Quantitation of GSTP1 methylation in non-neoplastic prostatic tissue and organ-confined prostate adenocarcinoma. (2001) (339)
Molecular detection of prostate cancer in urine by GSTP1 hypermethylation. (2001) (330)
Quantitative adenomatous polyposis coli promoter methylation analysis in tumor tissue, serum, and plasma DNA of patients with lung cancer. (2002) (314)
PD-L1 Expression in the Merkel Cell Carcinoma Microenvironment: Association with Inflammation, Merkel Cell Polyomavirus, and Overall Survival (2013) (309)
Multiple head and neck tumors: evidence for a common clonal origin. (1996) (300)
DNA methylation markers in colorectal cancer (2010) (295)
Promoter hypermethylation of multiple genes in carcinoma of the uterine cervix. (2001) (280)
Detection of bladder cancer recurrence by microsatellite analysis of urine (1997) (278)
A new human p53 homologue (1998) (278)
Head and Neck Cancer in CNonsmokers: A Distinct Clinical and Molecular Entity (1999) (277)
Inherited p53 gene mutations in breast cancer. (1992) (271)
A Quantitative Promoter Methylation Profile of Prostate Cancer (2004) (266)
Molecular detection of genetic alterations in the serum of colorectal cancer patients. (1998) (263)
MicroRNA alterations in head and neck squamous cell carcinoma (2008) (262)
Quantitation of promoter methylation of multiple genes in urine DNA and bladder cancer detection. (2006) (259)
Detection of mitochondrial DNA mutations in primary breast cancer and fine-needle aspirates. (2001) (259)
Detection of BRAF mutation on fine needle aspiration biopsy specimens: a new diagnostic tool for papillary thyroid cancer. (2004) (258)
Rapid p53 sequence analysis in primary lung cancer using an oligonucleotide probe array. (1999) (257)
Identification of a mononucleotide repeat as a major target for mitochondrial DNA alterations in human tumors. (2001) (255)
The Human MitoChip: a high-throughput sequencing microarray for mitochondrial mutation detection. (2004) (249)
Quantitative methylation-specific polymerase chain reaction gene patterns in urine sediment distinguish prostate cancer patients from control subjects. (2005) (247)
Assembly and Initial Characterization of a Panel of 85 Genomically Validated Cell Lines from Diverse Head and Neck Tumor Sites (2011) (241)
Mitochondrial mutations in early stage prostate cancer and bodily fluids (2001) (240)
p53 mutation and locoregional treatment failure in head and neck squamous cell carcinoma. (1996) (239)
Detection of aberrant methylation of four genes in plasma DNA for the detection of breast cancer. (2006) (237)
Somatic mutation and gain of copy number of PIK3CA in human breast cancer (2005) (232)
Frequent microsatellite instability in primary small cell lung cancer. (1994) (232)
Mutational Analysis of BRAF in Fine Needle Aspiration Biopsies of the Thyroid: A Potential Application for the Preoperative Assessment of Thyroid Nodules (2004) (230)
Genomic instability in human cancer: Molecular insights and opportunities for therapeutic attack and prevention through diet and nutrition (2015) (229)
Inverse Relationship between Human Papillomavirus-16 Infection and Disruptive p53 Gene Mutations in Squamous Cell Carcinoma of the Head and Neck (2008) (228)
Quantitative Detection of Promoter Hypermethylation of Multiple Genes in the Tumor, Urine, and Serum DNA of Patients with Renal Cancer (2004) (228)
Genetic progression and clonal relationship of recurrent premalignant head and neck lesions. (2000) (215)
Quantitative GSTP1 hypermethylation in bodily fluids of patients with prostate cancer. (2002) (212)
ΔNp63α and TAp63α regulate transcription of genes with distinct biological functions in cancer and development (2003) (207)
Infrequent p53 gene mutations in medulloblastomas. (1991) (205)
Clinical implications of the p53 gene. (1996) (205)
Uncommon mutation, but common amplifications, of the PIK3CA gene in thyroid tumors. (2005) (200)
p53 mutations and survival in stage I non-small-cell lung cancer: results of a prospective study. (2003) (198)
16S rRNA amplicon sequencing identifies microbiota associated with oral cancer, human papilloma virus infection and surgical treatment (2016) (198)
Frequency and phenotypic implications of mitochondrial DNA mutations in human squamous cell cancers of the head and neck (2007) (197)
Involvement of aquaporins in colorectal carcinogenesis (2003) (196)
Epithelial precursor lesions (2005) (195)
Designing a broad-spectrum integrative approach for cancer prevention and treatment. (2015) (194)
Bifunctional immune checkpoint-targeted antibody-ligand traps that simultaneously disable TGFβ enhance the efficacy of cancer immunotherapy (2018) (193)
Activation of the NOTCH pathway in head and neck cancer. (2014) (192)
Point mutation and homozygous deletion of PTEN/MMAC1 in primary bladder cancers (1998) (191)
Genetic divergence in the clonal evolution of breast cancer. (1996) (190)
ΔNp63 induces β-catenin nuclear accumulation and signaling (2002) (190)
Detection and quantitation of human papillomavirus (HPV) DNA in the sera of patients with HPV-associated head and neck squamous cell carcinoma. (2000) (190)
Patient-derived xenografts effectively capture responses to oncology therapy in a heterogeneous cohort of patients with solid tumors (2017) (187)
Multiple mechanisms of p16INK4A inactivation in non-small cell lung cancer cell lines. (1995) (185)
Quantitative detection of Merkel cell virus in human tissues and possible mode of transmission (2010) (183)
Detection of head and neck squamous cell carcinoma among exfoliated oral mucosal cells by microsatellite analysis. (2001) (183)
Chromosomal alterations in lung adenocarcinoma from smokers and nonsmokers. (2001) (182)
Serial analysis of gene expression in non-small cell lung cancer. (1998) (182)
Deletional, mutational, and methylation analyses of CDKN2 (p16/MTS1) in primary and metastatic prostate cancer (1997) (182)
Electrophile and oxidant damage of mitochondrial DNA leading to rapid evolution of homoplasmic mutations (2003) (181)
Global DNA hypomethylation is associated with in utero exposure to cotinine and perfluorinated alkyl compounds (2010) (181)
Analysis of PTEN/MMAC1 alterations in aerodigestive tract tumors. (1998) (179)
Homozygous deletions of 9p21 in primary human bladder tumors detected by comparative multiplex polymerase chain reaction. (1994) (176)
Mitochondrial Subversion in Cancer (2011) (175)
Mitochondrial D-loop mutations as clonal markers in multicentric hepatocellular carcinoma and plasma. (2002) (174)
Selective radiosensitization of p53–deficient cells by caffeine–mediated activation of p34cdc2 kinase (1996) (172)
Distinguishing second primary tumors from lung metastases in patients with head and neck squamous cell carcinoma. (1998) (172)
Gene promoter hypermethylation in tumors and lymph nodes of stage I lung cancer patients. (2003) (170)
Evaluation of Promoter Hypermethylation Detection in Body Fluids as a Screening/Diagnosis Tool for Head and Neck Squamous Cell Carcinoma (2008) (170)
Detection of Promoter Hypermethylation of Multiple Genes in the Tumor and Bronchoalveolar Lavage of Patients with Lung Cancer (2004) (169)
Rare loss-of-function mutation of a death receptor gene in head and neck cancer. (1998) (166)
Tumor‐specific changes in mtDNA content in human cancer (2005) (166)
Genome-wide genetic characterization of bladder cancer: a comparison of high-density single-nucleotide polymorphism arrays and PCR-based microsatellite analysis. (2003) (163)
Differential Recognition of Response Elements Determines Target Gene Specificity forp53 and p63 (2005) (163)
BRAF mutations in anaplastic thyroid carcinoma: implications for tumor origin, diagnosis and treatment (2004) (162)
Early Occurrence of RASSF1A Hypermethylation and Its Mutual Exclusion with BRAF Mutation in Thyroid Tumorigenesis (2004) (162)
Evidence for two bladder cancer suppressor loci on human chromosome 9. (1993) (161)
Aquaporin 1 is overexpressed in lung cancer and stimulates NIH-3T3 cell proliferation and anchorage-independent growth. (2006) (160)
Infrequent inactivation of the retinoblastoma gene despite frequent loss of chromosome 13q in head and neck squamous cell carcinoma. (1994) (159)
Participation of p 53 Protein in the Cellular Response to DNA Damage 1 (2006) (157)
Differential DNA Hypermethylation of Critical Genes Mediates the Stage-Specific Tobacco Smoke-Induced Neoplastic Progression of Lung Cancer (2005) (156)
Increased Mitochondrial DNA Content in Saliva Associated with Head and Neck Cancer (2005) (154)
Nucleotide substitution in the ectodomain of trail receptor DR4 is associated with lung cancer and head and neck cancer. (2001) (154)
Frequent loss of chromosome 9 in human primary non-small cell lung cancer. (1994) (154)
Habitual Risk Factors for Head and Neck Cancer (2004) (153)
Cold atmospheric plasma treatment selectively targets head and neck squamous cell carcinoma cells (2014) (152)
PGP9.5 as a candidate tumor marker for non-small-cell lung cancer. (1999) (152)
Mutant p53R175H upregulates Twist1 expression and promotes epithelial–mesenchymal transition in immortalized prostate cells (2011) (151)
Methylation of the thyroid-stimulating hormone receptor gene in epithelial thyroid tumors: a marker of malignancy and a cause of gene silencing. (2003) (150)
Aberrant promoter methylation and tumor suppressive activity of the DFNA5 gene in colorectal carcinoma (2008) (149)
Unknown primary head and neck squamous cell carcinoma: molecular identification of the site of origin. (1999) (148)
Integrated Next-Generation Sequencing and Avatar Mouse Models for Personalized Cancer Treatment (2014) (148)
Patient-derived xenografts for individualized care in advanced sarcoma (2014) (148)
Genome-wide promoter analysis uncovers portions of the cancer methylome. (2008) (148)
Real-time quantitative PCR demonstrates low prevalence of human papillomavirus type 16 in premalignant and malignant lesions of the oral cavity. (2002) (147)
Inactivation of the INK4A/ARF locus frequently coexists with TP53 mutations in non-small cell lung cancer (1999) (146)
Allelotype of posterior uveal melanoma: implications for a bifurcated tumor progression pathway. (1999) (146)
Adenomatous polyposis coli gene promoter hypermethylation in non-small cell lung cancer is associated with survival (2001) (145)
Promoter Hypermethylation as an Independent Prognostic Factor for Relapse in Patients with Prostate Cancer Following Radical Prostatectomy (2005) (144)
DeltaNp63alpha and TAp63alpha regulate transcription of genes with distinct biological functions in cancer and development. (2003) (143)
Quantitative GSTP1 methylation clearly distinguishes benign prostatic tissue and limited prostate adenocarcinoma. (2003) (142)
Role of human aquaporin 5 in colorectal carcinogenesis. (2008) (142)
Gene mutations in saliva as molecular markers for head and neck squamous cell carcinomas. (1994) (139)
The major 8p22 tumor suppressor DLC1 is frequently silenced by methylation in both endemic and sporadic nasopharyngeal, esophageal, and cervical carcinomas, and inhibits tumor cell colony formation (2007) (138)
Frequent gain of the p40/p51/p63 gene locus in primary head and neck squamous cell carcinoma (2000) (138)
Expression of Aquaporin 5 (AQP5) Promotes Tumor Invasion in Human Non Small Cell Lung Cancer (2008) (138)
Quantitative assessment of promoter methylation profiles in thyroid neoplasms. (2005) (136)
Corrigendum: A dual specificity kinase, DYRK1A, as a potential therapeutic target for head and neck squamous cell carcinoma (2017) (135)
Exon 15 BRAF Mutations Are Uncommon in Melanomas Arising in Nonsun-Exposed Sites (2004) (135)
Inverse Correlation between Cyclin A1 Hypermethylation and p53 Mutation in Head and Neck Cancer Identified by Reversal of Epigenetic Silencing (2004) (135)
Quantitative GSTP1 methylation and the detection of prostate adenocarcinoma in sextant biopsies. (2003) (134)
A transcriptional progression model for head and neck cancer. (2003) (134)
Alcohol consumption and cigarette smoking increase the frequency of p53 mutations in non-small cell lung cancer. (2000) (132)
Quantitative RARbeta2 hypermethylation: a promising prostate cancer marker. (2004) (131)
BRAF T1796A transversion mutation in various thyroid neoplasms. (2004) (130)
Somatic mutations of the PTEN tumor suppressor gene in sporadic follicular thyroid tumors (1998) (130)
High Promoter Methylation Levels of APC Predict Poor Prognosis in Sextant Biopsies from Prostate Cancer Patients (2007) (130)
A region of homozygous deletion on chromosome 9p21-22 in primary nasopharyngeal carcinoma. (1994) (129)
An Epigenetic Marker Panel for Detection of Lung Cancer Using Cell-Free Serum DNA (2011) (129)
Lack of BRAF mutation in primary uveal melanoma. (2003) (128)
Targeted sequencing reveals clonal genetic changes in the progression of early lung neoplasms and paired circulating DNA (2015) (127)
p53 associates with and targets ΔNp63 into a protein degradation pathway (2001) (123)
An Overview on the Isolation and Analysis of Circulating Tumor DNA in Plasma and Serum (2000) (123)
Intraoperative molecular margin analysis in head and neck cancer. (2004) (121)
Mitochondrial cytochrome B gene mutation promotes tumor growth in bladder cancer. (2008) (119)
The TGFβ-miR200-MIG6 pathway orchestrates the EMT-associated kinase switch that induces resistance to EGFR inhibitors. (2014) (119)
Partial allelotype of carcinoma in situ of the human bladder. (1995) (118)
Key tumor suppressor genes inactivated by “greater promoter” methylation and somatic mutations in head and neck cancer (2014) (118)
DeltaNp63 induces beta-catenin nuclear accumulation and signaling. (2002) (118)
Assessment of gene promoter hypermethylation for detection of cervical neoplasia (2006) (117)
Homozygous deletion on chromosome 9p and loss of heterozygosity on 9q, 6p, and 6q in primary human small cell lung cancer. (1994) (117)
Feasibility of quantitative PCR‐based saliva rinse screening of HPV for head and neck cancer (2005) (116)
Identification of hypermethylated genes associated with cisplatin resistance in human cancers. (2010) (116)
I105V polymorphism and promoter methylation of the GSTP1 gene in prostate adenocarcinoma. (2002) (116)
Progression of basal cell carcinoma through loss of chromosome 9q and inactivation of a single p53 allele. (1994) (115)
Detection of telomerase activity in oral rinses from head and neck squamous cell carcinoma patients. (1996) (115)
An EGFR-ERK-SOX9 signaling cascade links urothelial development and regeneration to cancer. (2011) (115)
PGP9.5 promoter methylation is an independent prognostic factor for esophageal squamous cell carcinoma. (2005) (114)
Novel suppressor loci on chromosome 14q in primary bladder cancer. (1995) (114)
NID2 and HOXA9 Promoter Hypermethylation as Biomarkers for Prevention and Early Detection in Oral Cavity Squamous Cell Carcinoma Tissues and Saliva (2011) (114)
Interaction and colocalization of PGP9.5 with JAB1 and p27Kip1 (2002) (111)
Mitochondrial C-tract alteration in premalignant lesions of the head and neck: a marker for progression and clonal proliferation. (2002) (111)
p16 and p16 beta are potent growth suppressors of head and neck squamous carcinoma cells in vitro. (1996) (109)
Molecular Analysis of Plasma DNA for the Early Detection of Lung Cancer by Quantitative Methylation-Specific PCR (2010) (106)
Localization of tumor suppressor loci on chromosome 9 in primary human renal cell carcinomas. (1995) (106)
Detection and quantitation of human papillomavirus DNA in the plasma of patients with cervical carcinoma. (2002) (105)
Immunohistochemical detection of p53 protein accumulation in head and neck cancer: correlation with p53 gene alterations. (1999) (105)
OPCML Is a Broad Tumor Suppressor for Multiple Carcinomas and Lymphomas with Frequently Epigenetic Inactivation (2008) (105)
Genetic and Epigenetic screening for gene alterations of the chromatin‐remodeling factor, SMARCA4/BRG1, in lung tumors (2004) (104)
Cancer epigenetics: above and beyond (2011) (103)
Identification of a novel region of homozygous deletion on chromosome 9p in squamous cell carcinoma of the lung: the location of a putative tumor suppressor gene. (1997) (102)
DeltaNp63alpha up-regulates the Hsp70 gene in human cancer. (2005) (102)
Molecular characteristics of non-small cell lung cancer (2001) (101)
ΔNp63α Up-Regulates the Hsp70 Gene in Human Cancer (2005) (101)
p63α Mutations Lead to Aberrant Splicing of Keratinocyte Growth Factor Receptor in the Hay-Wells Syndrome* (2003) (101)
Microsatellite instability in primary neoplasms from HIV+ patients (1995) (100)
Overexpression of c-met as a prognostic indicator for transitional cell carcinoma of the urinary bladder: a comparison with p53 nuclear accumulation. (2002) (99)
RACK1 and Stratifin Target ΔNp63α for a Proteasome Degradation in Head and Neck Squamous Cell Carcinoma Cells upon DNA Damage (2004) (97)
Methylation of the DFNA5 increases risk of lymph node metastasis in human breast cancer. (2008) (97)
Molecular detection of neoplastic cells in lymph nodes of metastatic colorectal cancer patients predicts recurrence. (1999) (97)
Cysteine Dioxygenase 1 Is a Tumor Suppressor Gene Silenced by Promoter Methylation in Multiple Human Cancers (2012) (97)
Ribonucleases as a Novel Pro-Apoptotic Anticancer Strategy: Review of the Preclinical and Clinical Data for Ranpirnase (2005) (96)
Mitochondrial DNA Content Increase in Response to Cigarette Smoking (2006) (96)
Epigenetic inactivation of RASSF1A in head and neck cancer. (2003) (96)
Distinct pattern of p53 phosphorylation in human tumors (2001) (96)
O6-Methylguanine-DNA Methyltransferase Promoter Hypermethylation Shifts the p53 Mutational Spectrum in Non-Small Cell Lung Cancer (2001) (96)
Optimal Use of a Panel of Methylation Markers with GSTP1 Hypermethylation in the Diagnosis of Prostate Adenocarcinoma (2004) (96)
Proteomic analysis of cancer-cell mitochondria (2003) (96)
Distinct regions of allelic loss on chromosome 4 in human primary bladder carcinoma. (1995) (96)
N-methyl-D-aspartate receptor type 2B is epigenetically inactivated and exhibits tumor-suppressive activity in human esophageal cancer. (2006) (94)
Analysis of p16 (CDKN2/MTS-1/INK4A) alterations in primary sporadic uveal melanoma. (1999) (94)
Second esophageal tumors in patients with head and neck squamous cell carcinoma: an assessment of clonal relationships. (1999) (94)
ΔNp63&alpha Overexpression Induces Downregulation of Sirt1 and an Accelerated Aging Phenotype in the Mouse (2006) (94)
Lactoferrin Down-Regulates G1 Cyclin-Dependent Kinases during Growth Arrest of Head and Neck Cancer Cells (2004) (93)
Molecular genetics of head and neck cancer (1995) (92)
A Panel of Novel Detection and Prognostic Methylated DNA Markers in Primary Non–Small Cell Lung Cancer and Serum DNA (2017) (91)
The RASSF1A tumor suppressor gene is commonly inactivated in adenocarcinoma of the uterine cervix. (2003) (91)
Epigenetic Heterogeneity of High-Grade Prostatic Intraepithelial Neoplasia: Clues for Clonal Progression in Prostate Carcinogenesis (2006) (91)
Microsatellite instability at selected tetranucleotide repeats is associated with p53 mutations in non-small cell lung cancer. (2000) (90)
Promoter DNA Methylation of Oncostatin M receptor-β as a Novel Diagnostic and Therapeutic Marker in Colon Cancer (2009) (90)
Overexpression of AQP5, a putative oncogene, promotes cell growth and transformation. (2008) (90)
LOXL1 and LOXL4 are epigenetically silenced and can inhibit ras/extracellular signal-regulated kinase signaling pathway in human bladder cancer. (2007) (90)
Phospho-ΔNp63α is a key regulator of the cisplatin-induced microRNAome in cancer cells (2011) (89)
In silico Pathway Activation Network Decomposition Analysis (iPANDA) as a method for biomarker development (2016) (89)
Mitochondrial DNA as a cancer biomarker. (2005) (89)
Increased plasma DNA integrity index in head and neck cancer patients (2006) (89)
p16INK4A adenovirus-mediated gene therapy for human head and neck squamous cell cancer. (1998) (88)
Detection of Promoter Hypermethylation in Salivary Rinses as a Biomarker for Head and Neck Squamous Cell Carcinoma Surveillance (2011) (87)
Colon cancer genetics (1992) (87)
RET proto-oncogene mutations in inherited and sporadic medullary thyroid cancer. (1994) (86)
Cyclin D1 amplification is independent of p16 inactivation in head and neck squamous cell carcinoma (1999) (86)
CDC91L1 (PIG-U) is a newly discovered oncogene in human bladder cancer (2004) (86)
Molecular techniques and genetic alterations in head and neck cancer. (2009) (85)
Prioritizing phase I treatment options through preclinical testing on personalized tumorgraft. (2012) (84)
KIF1A and EDNRB are differentially methylated in primary HNSCC and salivary rinses (2010) (84)
Frequent Loss of Chromosome Arms 8p and 13q in Collecting Duct Carcinoma (CDC) of the Kidney (1995) (83)
p53-Reactivating small molecules induce apoptosis and enhance chemotherapeutic cytotoxicity in head and neck squamous cell carcinoma. (2011) (81)
Changes in CpG Islands Promoter Methylation Patterns during Ductal Breast Carcinoma Progression (2009) (80)
Is human patched the gatekeeper of common skin cancers? (1996) (78)
Increased loss of chromosome 9p21 but not p16 inactivation in primary non-small cell lung cancer from smokers. (2001) (78)
A tumor-suppressive role for trypsin in human cancer progression. (2003) (77)
Human AQP5 Plays a Role in the Progression of Chronic Myelogenous Leukemia (CML) (2008) (77)
AIDS-related Kaposi's sarcoma is a clonal neoplasm. (1995) (77)
Selective growth inhibition in BRAF mutant thyroid cancer by the mitogen-activated protein kinase kinase 1/2 inhibitor AZD6244. (2007) (77)
Chromosome 9p21 loss and p16 inactivation in primary sclerosing cholangitis-associated cholangiocarcinoma. (1999) (76)
Allelic losses in OraTest-directed biopsies of patients with prior upper aerodigestive tract malignancy. (2001) (76)
Oxidized guanine lesions and hOgg1 activity in lung cancer (2005) (75)
Detection of c-myc amplification in uveal melanoma by fluorescent in situ hybridization. (2001) (75)
An oligonucleotide microarray for high-throughput sequencing of the mitochondrial genome. (2006) (75)
Mitochondrial DNA mutations in respiratory complex‐I in never‐smoker lung cancer patients contribute to lung cancer progression and associated with EGFR gene mutation (2012) (74)
Notch1 Mutations Are Drivers of Oral Tumorigenesis (2014) (74)
Brief report: molecular biology and the early detection of carcinoma of the bladder--the case of Hubert H. Humphrey. (1994) (74)
Mutation analysis of hBUB1 in aneuploid HNSCC and lung cancer cell lines. (1999) (73)
ΔNp63α Levels Correlate with Clinical Tumor Response to Cisplatin (2005) (73)
Aberrant Promoter Methylation of Multiple Genes during Pathogenesis of Bladder Cancer (2008) (73)
Endothelin Receptor Type B Gene Promoter Hypermethylation in Salivary Rinses Is Independently Associated with Risk of Oral Cavity Cancer and Premalignancy (2010) (73)
p53 Regulates the Ras circuit to inhibit the expression of a cancer-related gene signature by various molecular pathways. (2010) (73)
Expression status and prognostic significance of mammalian target of rapamycin pathway members in urothelial carcinoma of urinary bladder after cystectomy (2010) (72)
The effect of aquaporin 5 overexpression on the Ras signaling pathway. (2008) (72)
Integrated, Genome-Wide Screening for Hypomethylated Oncogenes in Salivary Gland Adenoid Cystic Carcinoma (2011) (72)
Serum protein MALDI profiling to distinguish upper aerodigestive tract cancer patients from control subjects. (2003) (72)
Deleted in colorectal cancer is a putative conditional tumor-suppressor gene inactivated by promoter hypermethylation in head and neck squamous cell carcinoma. (2006) (72)
Association between Lifestyle Factors and CpG Island Methylation in a Cancer-Free Population (2009) (71)
High-density mapping of chromosomal arm 1q in renal collecting duct carcinoma: region of minimal deletion at 1q32.1-32.2. (1996) (70)
MT1G Hypermethylation Is Associated with Higher Tumor Stage in Prostate Cancer (2005) (70)
Hypermethylation of the Pendred syndrome gene SLC26A4 is an early event in thyroid tumorigenesis. (2003) (69)
Inverse correlation between RASSF1A hypermethylation, KRAS and BRAF mutations in cervical adenocarcinoma. (2007) (69)
Performance of mitochondrial DNA mutations detecting early stage cancer (2008) (69)
PGP9.5 methylation in diffuse-type gastric cancer. (2006) (68)
Molecular genetics and biochemical mechanisms in bladder cancer. Oncogenes, tumor suppressor genes, and growth factors. (1992) (68)
Aquaporin expression in human lymphocytes and dendritic cells (2004) (68)
Distal nephron renal tumors: microsatellite allelotype. (1996) (68)
A p53-type response element in the GDF15 promoter confers high specificity for p53 activation. (2007) (67)
Microsatellite‐based cancer detection using capillary array electrophoresis and energy‐transfer fluorescent primers (1997) (67)
p53 and p21(WAF1/CIP1/SDI1) gene products in Barrett esophagus and adenocarcinoma of the esophagus and esophagogastric junction. (1996) (67)
Inverted sinonasal papilloma : a molecular genetic appraisal of its putative status as a Precursor to squamous cell carcinoma. (2000) (66)
Mitochondrial DNA mutations in preneoplastic lesions of the gastrointestinal tract: A biomarker for the early detection of cancer (2006) (66)
p53 associates with and targets Delta Np63 into a protein degradation pathway. (2001) (66)
RACK1 and stratifin target DeltaNp63alpha for a proteasome degradation in head and neck squamous cell carcinoma cells upon DNA damage. (2004) (66)
A survey of methylated candidate tumor suppressor genes in nasopharyngeal carcinoma (2011) (65)
Midkine induces epithelial-mesenchymal transition through Notch2/Jak2-Stat3 signaling in human keratinocytes (2008) (65)
Molecular detection approaches for smoking associated tumors (2002) (65)
Mutational activation of BRAF is not a major event in sporadic childhood papillary thyroid carcinoma (2005) (65)
Potential utility of HOP homeobox gene promoter methylation as a marker of tumor aggressiveness in gastric cancer (2010) (65)
T1799A BRAF mutations in conjunctival melanocytic lesions. (2005) (65)
Loss of heterozygosity patterns provide fingerprints for genetic heterogeneity in multistep cancer progression of tobacco smoke-induced non-small cell lung cancer. (2005) (64)
Squamous cell carcinoma of the head and neck in the elderly. (1995) (64)
Altered Sumoylation of p63α Contributes to the Split-Hand/Foot Malformation Phenotype (2004) (64)
YAP1 and COX2 Coordinately Regulate Urothelial Cancer Stem-like Cells. (2018) (63)
p53 overexpression and K-ras gene mutations in primary sclerosing cholangitis-associated biliary tract cancer. (2000) (63)
Efficacy of weekly docetaxel and bevacizumab in mesenchymal chondrosarcoma: a new theranostic method combining xenografted biopsies with a mathematical model. (2008) (63)
Mutator phenotype in a subset of chronic lymphocytic leukemia. (1996) (62)
The role of PGP9.5 as a tumor suppressor gene in human cancer (2008) (62)
Correlation between BRAF mutation and promoter methylation of TIMP3, RARβ2 and RASSF1A in thyroid cancer (2012) (62)
Papillary urothelial hyperplasia is a clonal precursor to papillary transitional cell bladder cancer. (1999) (62)
High-resolution microbiome profiling uncovers Fusobacterium nucleatum, Lactobacillus gasseri/johnsonii, and Lactobacillus vaginalis associated to oral and oropharyngeal cancer in saliva from HPV positive and HPV negative patients treated with surgery and chemo-radiation (2017) (62)
Fine mapping of chromosome 3 in uveal melanoma: identification of a minimal region of deletion on chromosomal arm 3p25.1-p25.2. (2003) (61)
Endothelin B receptor gene hypermethylation in prostate adenocarcinoma (2003) (61)
Genetic Alterations in Urinary Bladder Carcinosarcoma: Evidence of a Common Clonal Origin (2000) (61)
Absence of V599E BRAF mutations in desmoplastic melanomas (2005) (61)
Biallelic inactivation of the RIZ1 gene in human gastric cancer (2003) (61)
Microsatellite instability at AAAG repeat sequences in respiratory tract cancers (2001) (60)
Quantitative hypermethylation of a small panel of genes augments the diagnostic accuracy in fine-needle aspirate washings of breast lesions (2008) (60)
Detecting cervical cancer by quantitative promoter hypermethylation assay on cervical scrapings: a feasibility study. (2004) (60)
Tissue inhibitor of metalloproteinases-3 promoter methylation is an independent prognostic factor for bladder cancer. (2008) (59)
Gene expression alterations over large chromosomal regions in cancers include multiple genes unrelated to malignant progression. (2004) (59)
Inhibition of TGF-β Enhances the In Vivo Antitumor Efficacy of EGF Receptor–Targeted Therapy (2012) (59)
LKB1 protein expression in the evolution of glandular neoplasia of the lung. (2003) (59)
Pharmacologic Unmasking of Epigenetically Silenced Genes in Breast Cancer (2009) (59)
Microsatellite analysis and telomerase activity in archived tissue and urine samples of bladder cancer patients (1997) (59)
DCC promoter hypermethylation in esophageal squamous cell carcinoma (2006) (58)
Hypermethylation of Cyclin D2 is associated with loss of mRNA expression and tumor development in prostate cancer (2006) (58)
Mutations in the conserved regions of p53 are infrequent in betel-associated oral cancers from Papua New Guinea. (1994) (58)
Impact of chromosome 14q loss on survival in primary head and neck squamous cell carcinoma. (1997) (58)
High-throughput molecular analysis of urine sediment for the detection of bladder cancer by high-density single-nucleotide polymorphism array. (2003) (58)
OGDHL Is a Modifier of AKT-Dependent Signaling and NF-κB Function (2012) (58)
DeltaNp63alpha levels correlate with clinical tumor response to cisplatin. (2005) (58)
Epigenetic silencing of HOPX promotes cancer progression in colorectal cancer. (2012) (57)
Increased expression and activity of repair genes TDP1 and XPF in non-small cell lung cancer. (2007) (57)
Quantitative hypermethylation of NMDAR2B in human gastric cancer (2007) (57)
Mitochondrial DNA Mutation in Normal Margins and Tumors of Recurrent Head and Neck Squamous Cell Carcinoma Patients (2010) (57)
Overexpression of glycosylphosphatidylinositol (GPI) transamidase subunits phosphatidylinositol glycan class T and/or GPI anchor attachment 1 induces tumorigenesis and contributes to invasion in human breast cancer. (2006) (56)
Methylation of death-associated protein kinase is associated with cetuximab and erlotinib resistance (2012) (56)
Mutation of p53 in head and neck squamous cell carcinoma correlates with Bcl‐2 expression and increased susceptibility to cisplatin‐induced apoptosis (2004) (55)
Allelotype of salivary gland tumors. (1996) (55)
Death-associated protein kinase promoter hypermethylation in normal human lymphocytes. (2003) (55)
Targeting of mutant hogg1 in mammalian mitochondria and nucleus: effect on cellular survival upon oxidative stress (2006) (54)
Molecular differential diagnosis of renal carcinoma: from microscopes to microsatellites. (1996) (53)
Decreased Mitochondrial DNA Content in Posttreatment Salivary Rinses from Head and Neck Cancer Patients (2006) (53)
Loss of heterozygosity assay for molecular detection of cancer using energy-transfer primers and capillary array electrophoresis. (2000) (53)
Progression of microsatellite instability from premalignant lesions to tumors of the head and neck (2002) (53)
The KRAS-Variant and Cetuximab Response in Head and Neck Squamous Cell Cancer: A Secondary Analysis of a Randomized Clinical Trial (2017) (52)
Detection of LOH and Mitochondrial DNA Alterations in Ductal Lavage and Nipple Aspirate Fluids from High-risk Patients (2004) (52)
Quantitative GSTP1 methylation levels correlate with Gleason grade and tumor volume in prostate needle biopsies. (2004) (52)
Identification of head and neck squamous cell carcinoma biomarker candidates through proteomic analysis of cancer cell secretome. (2013) (52)
Molecular Profiling of Malignant Pleural Effusion in Metastatic Non‐Small‐Cell Lung Carcinoma. The Effect of Preanalytical Factors (2017) (52)
The effect of p53‐RNAi and p53 knockout on human 8‐oxoguanine DNA glycosylase (hOgg1) activity (2006) (51)
Profiling the expression pattern of GPI transamidase complex subunits in human cancer (2008) (51)
Molecular analysis of the candidate tumor suppressor gene ING1 in human head and neck tumors with 13q deletions (2000) (51)
Frequent 14-3-3σ promoter methylation in benign and malignant prostate lesions (2005) (51)
Diagnosis of Renal Cancer by Molecular Urinalysis (1999) (51)
Epstein‐Barr Virus in Head and Neck Cancer Assessed by Quantitative Polymerase Chain Reaction (2004) (51)
SMAD4 Loss Is Associated with Cetuximab Resistance and Induction of MAPK/JNK Activation in Head and Neck Cancer Cells (2017) (51)
Membrane trafficking of AQP5 and cAMP dependent phosphorylation in bronchial epithelium. (2008) (50)
p63-specific activation of the BPAG-1e promoter. (2005) (50)
Abstract 1287: Epigenetic deregulation of breast cancer is associated with DNA Repair Capacity. (2013) (50)
Detection of serum deoxyribonucleic acid methylation markers: a novel diagnostic tool for thyroid cancer. (2006) (50)
Adenylate Kinase 3 Sensitizes Cells to Cigarette Smoke Condensate Vapor Induced Cisplatin Resistance (2011) (49)
Detection of tumor mutations in the presence of excess amounts of normal DNA (2002) (49)
Characterization of the Methylation Patterns in Human Papillomavirus Type 16 Viral DNA in Head and Neck Cancers (2011) (49)
LKB1/STK11 suppresses cyclooxygenase-2 induction and cellular invasion through PEA3 in lung cancer. (2006) (49)
Screening of homologous recombination gene polymorphisms in lung cancer patients reveals an association of the NBS1-185Gln variant and p53 gene mutations. (2003) (48)
Patient‐derived xenografts as tools in pharmaceutical development (2016) (47)
BORIS Binding to the Promoters of Cancer Testis Antigens, MAGEA2, MAGEA3, and MAGEA4, Is Associated with Their Transcriptional Activation in Lung Cancer (2011) (47)
p53 gene mutations as markers of tumor spread in synchronous oral cancers. (1994) (47)
HOP/OB1/NECC1 Promoter DNA Is Frequently Hypermethylated and Involved in Tumorigenic Ability in Esophageal Squamous Cell Carcinoma (2008) (47)
Mitochondrial DNA alterations in thyroid cancer (2003) (46)
GSTP1 promoter methylation is associated with recurrence in early stage prostate cancer. (2014) (46)
Involvement of Epigenetics and EMT-Related miRNA in Arsenic-Induced Neoplastic Transformation and Their Potential Clinical Use (2015) (46)
Adenoid cystic carcinoma: emerging role of translocations and gene fusions (2016) (46)
ATM kinase is a master switch for the ΔNp63α phosphorylation/degradation in human head and neck squamous cell carcinoma cells upon DNA damage (2008) (46)
DeltaNp63alpha confers tumor cell resistance to cisplatin through the AKT1 transcriptional regulation. (2011) (46)
PARD3 Inactivation in Lung Squamous Cell Carcinomas Impairs STAT3 and Promotes Malignant Invasion. (2015) (45)
Molecular margin analysis predicts local recurrence after sublobar resection of lung cancer (2005) (45)
Differential promoter methylation of kinesin family member 1a in plasma is associated with breast cancer and DNA repair capacity (2014) (44)
Regulation of p53 family member isoform DeltaNp63alpha by the nuclear factor-kappaB targeting kinase IkappaB kinase beta. (2010) (44)
PD-L 1 Expression in the Merkel Cell Carcinoma Microenvironment : Association with In fl ammation , Merkel Cell Polyomavirus , and Overall Survival (2013) (44)
A randomized phase II efficacy and correlative studies of cetuximab with or without sorafenib in recurrent and/or metastatic head and neck squamous cell carcinoma. (2015) (44)
An allelotype of papillary thyroid cancer (1996) (44)
Characterization of a Human Homologue of Proteolysis-Inducing Factor and Its Role in Cancer Cachexia (2004) (44)
Cigarette smoke induces promoter methylation of single‐stranded DNA‐binding protein 2 in human esophageal squamous cell carcinoma (2011) (44)
Neurofilament Heavy Polypeptide Regulates the Akt-β-Catenin Pathway in Human Esophageal Squamous Cell Carcinoma (2010) (43)
Immune profiles in primary squamous cell carcinoma of the head and neck. (2019) (43)
Methylation status in the promoter region of the human PGP9.5 gene in cancer and normal tissues. (2001) (42)
KRAS Mutation Status Is Associated with Enhanced Dependency on Folate Metabolism Pathways in Non–Small Cell Lung Cancer Cells (2014) (42)
Cleaved NOTCH1 Expression Pattern in Head and Neck Squamous Cell Carcinoma Is Associated with NOTCH1 Mutation, HPV Status, and High-Risk Features (2015) (42)
Quantitative detection of promoter hypermethylation as a biomarker of acute kidney injury during transplantation. (2006) (42)
Microsatellite analysis of serum DNA in patients with head and neck cancer (2004) (42)
p63 Transcriptional Regulation of Epithelial Integrity and Cancer (2007) (42)
Circulating DNA: What We Know and What We Need to Learn (2000) (42)
Molecular methods for the diagnosis of cancer. (1999) (41)
Detailed deletion mapping at chromosome 9p21 in non‐small cell lung cancer by microsatellite analysis and fluorescence in situ hybridization (1997) (41)
The V599E BRAF mutation is uncommon in biliary tract cancers (2004) (41)
O(6)-Methylguanine-DNA methyltransferase promoter hypermethylation shifts the p53 mutational spectrum in non-small cell lung cancer. (2001) (41)
Hypermethylation of MCAM gene is associated with advanced tumor stage in prostate cancer (2008) (41)
Comparison of oncogene mutation detection and telomerase activity for the molecular staging of non-small cell lung cancer. (1997) (41)
Papillary urothelial hyperplasia is a clonal precursor to papillary transitional cell bladder cancer (2000) (41)
A putative oncogenic role for MPP11 in head and neck squamous cell cancer. (2000) (41)
Molecular assessment of lymph nodes in patients with resected stage I non-small cell lung cancer: preliminary results of a prospective study. (2002) (40)
An integrated genome-wide approach to discover deregulated microRNAs in non-small cell lung cancer: Clinical significance of miR-23b-3p deregulation (2015) (40)
Functional analysis of wild-type and malignant glioma derived CDKN2Aβ alleles: Evidence for an RB-independent growth suppressive pathway (1997) (40)
NSD1- and NSD2-damaging mutations define a subset of laryngeal tumors with favorable prognosis (2017) (39)
Mouse mammary tumor‐like env gene as a molecular marker for breast cancer? (2002) (39)
A novel response element confers p63- and p73-specific activation of the WNT4 promoter. (2006) (39)
Pathway activation strength is a novel independent prognostic biomarker for cetuximab sensitivity in colorectal cancer patients (2015) (39)
Pro-fibrotic pathway activation in trabecular meshwork and lamina cribrosa is the main driving force of glaucoma (2016) (38)
Integrated Analysis of Whole-Genome ChIP-Seq and RNA-Seq Data of Primary Head and Neck Tumor Samples Associates HPV Integration Sites with Open Chromatin Marks. (2017) (38)
The N-methyl-D-aspartate receptor type 2A is frequently methylated in human colorectal carcinoma and suppresses cell growth (2008) (37)
Genome-wide methylation profiling and the PI3K-AKT pathway analysis associated with smoking in urothelial cell carcinoma (2013) (37)
Epigenetic silencing of human T (brachyury homologue) gene in non-small-cell lung cancer. (2008) (37)
Frequent 14-3-3 sigma promoter methylation in benign and malignant prostate lesions. (2005) (36)
Prognostic significance of preoperative molecular serum analysis in renal cancer. (2002) (36)
A dual specificity kinase, DYRK1A, as a potential therapeutic target for head and neck squamous cell carcinoma (2016) (36)
Early detection of gastric cancer using global, genome-wide and IRF4, ELMO1, CLIP4 and MSC DNA methylation in endoscopic biopsies (2017) (36)
The Ligamp TP53 Assay for Detection of Minimal Residual Disease in Head and Neck Squamous Cell Carcinoma Surgical Margins (2009) (36)
Common pathway signature in lung and liver fibrosis (2016) (36)
Spindle assembly checkpoint defects and chromosomal instability in head and neck squamous cell carcinoma (2003) (35)
U-box-type ubiquitin E4 ligase, UFD2a attenuates cisplatin mediated degradation of ΔNp63α (2008) (35)
Fluorescence Visualization in Oral Neoplasia: Shedding Light on an Old Problem (2006) (35)
PUMA in head and neck cancer. (2003) (35)
The Relative Expression of Mig6 and EGFR Is Associated with Resistance to EGFR Kinase Inhibitors (2013) (34)
Suprabasin Is Hypomethylated and Associated with Metastasis in Salivary Adenoid Cystic Carcinoma (2012) (34)
Molecular staging of head and neck squamous carcinoma (1996) (34)
Hypermethylation of Genes Detected in Urine from Ghanaian Adults with Bladder Pathology Associated with Schistosoma haematobium Infection (2013) (34)
RASSF1A hypermethylation and its inverse correlation with BRAF and/or KRAS mutations in MSI‐associated endometrial carcinoma (2006) (34)
Elevated AKAP12 in paclitaxel-resistant serous ovarian cancer cells is prognostic and predictive of poor survival in patients. (2015) (33)
Molecular markers in cancer: Can we make better predictions? (1995) (33)
Mutational spectra and immunohistochemical analyses of p53 in human cancers. (1992) (33)
Forced cytochrome B gene mutation expression induces mitochondrial proliferation and prevents apoptosis in human uroepithelial SV‐HUC‐1 cells (2009) (33)
Phenotypic and genotypic disparity in premalignant lesions: of calm water and crocodiles. (1998) (33)
Induction of markers of normal differentiation in human colon carcinoma cells by the v-rasH oncogene. (1993) (33)
An accelerated pathway for targeted cancer therapies (2011) (32)
Association of Promoter Methylation of VGF and PGP9.5 with Ovarian Cancer Progression (2013) (32)
Silencing of high‐mobility group box 2 (HMGB2) modulates cisplatin and 5‐fluorouracil sensitivity in head and neck squamous cell carcinoma (2015) (32)
Macrophage migration inhibitory factor - a therapeutic target in gallbladder cancer (2015) (32)
Dose-Dependent Activation of Putative Oncogene SBSN by BORIS (2012) (32)
Molecular screening. Prospects for a new approach. (1993) (32)
ssDNA-Binding Protein 2 Is Frequently Hypermethylated and Suppresses Cell Growth in Human Prostate Cancer (2008) (31)
Cigarette smoke and chewing tobacco alter expression of different sets of miRNAs in oral keratinocytes (2018) (31)
Head and neck cancer cell lines exhibit differential mitochondrial repair deficiency in response to 4NQO. (2006) (31)
Genetic markers for early detection of lung cancer and outcome measures for response to chemoprevention (1997) (31)
Genome-wide profiling of non-smoking-related lung cancer cells reveals common RB1 rearrangements associated with histopathologic transformation in EGFR-mutant tumors. (2020) (30)
The Ras Effector RASSF2 Controls the PAR-4 Tumor Suppressor (2010) (30)
Diagnosis of renal cancer by molecular urinalysis. (1999) (30)
Clinical Correlates of Promoter Hypermethylation of Four Target Genes in Head and Neck Cancer: A Cooperative Group Correlative Study (2013) (30)
Genetic and Epigenetic Analysis of erbB Signaling Pathway Genes in Lung Cancer (2010) (29)
Promoter methylation of MCAM, ERα and ERβ in serum of early stage prostate cancer patients (2017) (29)
Chronic exposure to cigarette smoke leads to activation of p21 (RAC1)-activated kinase 6 (PAK6) in non-small cell lung cancer cells (2016) (29)
Quantitative Methylation Profiles for Multiple Tumor Suppressor Gene Promoters in Salivary Gland Tumors (2010) (29)
Alteration of Cellular and Humoral Immunity by Mutant p53 Protein and Processed Mutant Peptide in Head and Neck Cancer (2007) (28)
Germline translocation t(5;20)(p15;q11) and familial transitional cell carcinoma. (1996) (28)
Real-Time Gap Ligase Chain Reaction (2004) (28)
The RASSF 1 A Tumor Suppressor Gene Is Commonly Inactivated in Adenocarcinoma of the Uterine Cervix (2003) (28)
Identification of guanine nucleotide-binding protein γ-7 as an epigenetically silenced gene in head and neck cancer by gene expression profiling (2013) (28)
Chronic exposure to chewing tobacco selects for overexpression of stearoyl-CoA desaturase in normal oral keratinocytes (2015) (27)
Molecular Triage of Premalignant Lesions in Liquid-Based Cervical Cytology and Circulating Cell-Free DNA from Urine, Using a Panel of Methylated Human Papilloma Virus and Host Genes (2016) (27)
Following Mitochondrial Footprints through a Long Mucosal Path to Lung Cancer (2009) (27)
Genome-wide methylation profiling reveals Zinc finger protein 516 (ZNF516) and FK-506-binding protein 6 (FKBP6) promoters frequently methylated in cervical neoplasia, associated with HPV status and ethnicity in a Chilean population (2014) (27)
Words matter: distinguishing "personalized medicine" and "biologically personalized therapeutics". (2014) (26)
ATM kinase is a master switch for the Delta Np63 alpha phosphorylation/degradation in human head and neck squamous cell carcinoma cells upon DNA damage. (2008) (26)
MDA-9/Syntenin regulates differentiation and angiogenesis programs in head and neck squamous cell carcinoma (2014) (26)
The Oral Cavity as a Molecular Mirror of Lung Carcinogenesis (2008) (25)
Dysregulation of splicing proteins in head and neck squamous cell carcinoma (2016) (25)
SH3GL2 is frequently deleted in non-small cell lung cancer and downregulates tumor growth by modulating EGFR signaling (2013) (25)
Normal polymorphism in the incomplete trinucleotide repeat of the arginine-rich protein gene. (1997) (25)
Multiple strand displacement amplification of mitochondrial DNA from clinical samples (2008) (25)
A comparison between microsatellite and quantitative PCR analyses to detect frequent p16 copy number changes in primary bladder tumors. (1998) (24)
Cigarette smoke induces methylation of the tumor suppressor gene NISCH (2013) (24)
Sensitization to UV-induced apoptosis by the histone deacetylase inhibitor trichostatin A (TSA). (2005) (24)
Cancer screening based on genetic alterations in human tumors. (1994) (24)
Clusterin Is a Gene-Specific Target of microRNA-21 in Head and Neck Squamous Cell Carcinoma (2013) (24)
Detection of Methylated CDO1 in Plasma of Colorectal Cancer; A PCR Study (2014) (24)
Genomic organization and mutation analysis of Hel-N1 in lung cancers with chromosome 9p21 deletions. (1997) (24)
Prognostic Significance of Promoter DNA Hypermethylation of cysteine dioxygenase 1 (CDO1) Gene in Primary Breast Cancer (2016) (24)
Phospho-ΔNp63α/NF-Y protein complex transcriptionally regulates DDIT3 expression in squamous cell carcinoma cells upon cisplatin exposure (2010) (24)
Global and gene-specific DNA methylation pattern discriminates cholecystitis from gallbladder cancer patients in Chile (2014) (24)
Molecular screening--how long can we afford to wait? (1994) (24)
Cellular transformation by cigarette smoke extract involves alteration of glycolysis and mitochondrial function in esophageal epithelial cells (2010) (23)
Predominance of brain tumors in an extended Li‐Fraumeni (SBLA) kindred, including a case of Sturge‐Weber syndrome (2000) (23)
A Promoter Methylation Pattern in the N-Methyl-d-Aspartate Receptor 2B Gene Predicts Poor Prognosis in Esophageal Squamous Cell Carcinoma (2007) (23)
Long-Term Cigarette Smoke Exposure and Changes in MiRNA Expression and Proteome in Non-Small-Cell Lung Cancer. (2017) (23)
Paired Box 5 Methylation Detection by Droplet Digital PCR for Ultra-Sensitive Deep Surgical Margins Analysis of Head and Neck Squamous Cell Carcinoma (2015) (23)
U-box-type ubiquitin E4 ligase, UFD2a attenuates cisplatin mediated degradation of DeltaNp63alpha. (2008) (23)
In silico analysis of pathways activation landscape in oral squamous cell carcinoma and oral leukoplakia (2017) (22)
Promoter methylation of leukemia inhibitory factor receptor gene in colorectal carcinoma. (2011) (22)
Advances in Brief Promoter Hypermethylation Patterns of p 16 , O 6-Methylguanine-DNA-methyltransferase , and Death-associated Protein Kinase in Tumors and Saliva of Head and Neck Cancer Patients 1 (2001) (21)
Detection of mitochondrial deoxyribonucleic acid alterations in urine from urothelial cell carcinoma patients (2012) (21)
Validation of nucleolar protein 4 as a novel methylated tumor suppressor gene in head and neck cancer (2013) (21)
Regulation of ΔNp63α by NFκΒ (2010) (21)
Advances in Brief Inactivation of the DNA Repair Gene O 6-Methylguanine-DNA Methyltransferase by Promoter Hypermethylation Is Associated with G to A Mutations in Kras in Colorectal Tumorigenesis 1 (2000) (21)
Presence of 5-methylcytosine in CpNpG trinucleotides in the human genome. (2010) (20)
Multiple Mechanisms of p 16 @ NK 4 AInactivation in Non-Small Cell Lung Cancer Cell Lines (20)
Tissue and Cell-Free DNA-Based Epigenomic Approaches for Cancer Detection. (2019) (20)
Two distinct regions of loss on chromosome arm 4q in primary head and neck squamous cell carcinoma. (2000) (20)
Positive Correlation of Tissue Inhibitor of Metalloproteinase‐3 and Death‐Associated Protein Kinase Hypermethylation in Head and Neck Squamous Cell Carcinoma (2007) (20)
Biomarkers for Lung Cancer Screening and Detection (2020) (20)
MGMT inactivation and clinical response in newly diagnosed GBM patients treated with Gliadel (2015) (19)
Cigarette smoke induces mitochondrial metabolic reprogramming in lung cells. (2018) (19)
Epigenetic inactivation of VGF associated with Urothelial Cell Carcinoma and its potential as a non-invasive biomarker using urine (2014) (19)
Loss of chromosome arms 3p and 9p and inactivation of P16 INK4a in normal epithelium of patients with primary lung cancer (2001) (19)
miRNA and Proteomic Dysregulation in Non-Small Cell Lung Cancer in Response to Cigarette Smoke. (2018) (19)
Degenerate oligonucleotide-primed PCR (DOP-PCR): evaluation of its reliability for screening of genetic alterations in neoplasia. (1998) (19)
An epigenetic marker panel for recurrence risk prediction of low grade papillary urothelial cell carcinoma (LGPUCC) and its potential use for surveillance after transurethral resection using urine (2014) (19)
Tissue imprint for molecular mapping of deep surgical margins in patients with head and neck squamous cell carcinoma (2012) (18)
Chronic Cigarette Smoke Mediated Global Changes in Lung Mucoepidermoid Cells: A Phosphoproteomic Analysis. (2017) (18)
AIM1 promoter hypermethylation as a predictor of decreased risk of recurrence following radical prostatectomy (2012) (18)
Circulating antibodies to p40AIS in the sera of respiratory tract cancer patients (2000) (18)
Alterations of GPI transamidase subunits in head and neck squamous carcinoma (2007) (18)
Use of single nucleotide polymorphism arrays to identify a novel region of loss on chromosome 6q in squamous cell carcinomas of the oral cavity (2004) (18)
Molecular detection of cervical intraepithelial neoplasia and cervical carcinoma by microsatellite analysis of Papanicolaou smears (2001) (17)
Detection of adenocarcinoma by urinary microsatellite analysis after augmentation cystoplasty. (1999) (17)
Molecular alterations associated with chronic exposure to cigarette smoke and chewing tobacco in normal oral keratinocytes (2017) (17)
Cellular FLICE-like Inhibitory Protein Long Form (c-FLIPL) Overexpression is Related to Cervical Cancer Progression (2013) (17)
Role of protein kinase N2 (PKN2) in cigarette smoke-mediated oncogenic transformation of oral cells (2018) (17)
Re: Is TIG1 a new tumor suppressor in prostate cancer? (2003) (17)
Evaluation of MYB promoter methylation in salivary adenoid cystic carcinoma. (2011) (17)
Advances in cancer detection. (1996) (16)
Tumor Protein p63/Nuclear Factor κB Feedback Loop in Regulation of Cell Death* (2011) (16)
Identification of mtDNA mutations in human cancer. (2002) (16)
Absence of ST7 gene alterations in human cancer. (2002) (16)
Molecular Analysis of Peritoneal Fluid in Ovarian Cancer Patients (2003) (16)
Molecular markers of radiation effectiveness in head and neck squamous cell carcinoma. (2004) (15)
Basal cell carcinoma-like epidermal changes overlying dermatofibromas often reveal loss of heterozygosity in the PTCH gene. (1999) (15)
Human Cancers Associated with Aberrant DNA Methylation in All Common Gene Is Frequently CDKN 2 / p 16 / MTS 1 Inactivation of the Updated (2006) (15)
Yes-associated protein 1 regulates the stability of ΔNp63α (2010) (15)
Chronic Exposure to Chewing Tobacco Induces Metabolic Reprogramming and Cancer Stem Cell-Like Properties in Esophageal Epithelial Cells (2019) (15)
p63 and p73: teammates or adversaries? (2006) (15)
The potential of molecular screening. (1999) (15)
LOXL 1 and LOXL 4 Are Epigenetically Silenced and Can Inhibit Ras / Extracellular Signal-Regulated Kinase Signaling Pathway in Human Bladder Cancer (2007) (15)
Lack of BRCA2 alterations in primary head and neck squamous cell carcinoma (1998) (14)
Detection of Merkel cell virus and correlation with histologic presence of Merkel cell carcinoma in sentinel lymph nodes (2012) (14)
CLINICAL IMPLICATIONS OF THE p 53 GENE (1996) (14)
Mutations and Survival in Stage I Non-Small-Cell Lung Cancer : Results of a Prospective Study (2003) (13)
Promoter Methylation Is an Independent Prognostic Factor for Esophageal Squamous Cell Carcinoma (2005) (13)
Inactivation of LKB 1 / STK 11 Is a Common Event in Adenocarcinomas of the Lung 1 (2002) (13)
Genome-Wide and Gene-Specific Epigenomic Platforms for Hepatocellular Carcinoma Biomarker Development Trials (2014) (13)
Chromatin structure regulates cancer-specific alternative splicing events in primary HPV-related oropharyngeal squamous cell carcinoma (2020) (13)
Correction: OPCML Is a Broad Tumor Suppressor for Multiple Carcinomas and Lymphomas with Frequently Epigenetic Inactivation (2008) (13)
Antiviral effect of ranpirnase against Ebola virus. (2016) (13)
Advances in Brief p 53 Mutation and MDM 2 Amplification in Human Soft Tissue Sarcomas 1 (2006) (12)
Efficacy of weekly docetaxel and bevacizumab in mesenchymal chondrosarcoma: A new theranostic method combining xenografted biopsies with a mathematical model (Cancer Research (November 1, 2008) 68 (9033-9040)) (2008) (12)
Targeting focal adhesion kinase overcomes erlotinib resistance in smoke induced lung cancer by altering phosphorylation of epidermal growth factor receptor (2018) (12)
Absence of TSG101 transcript abnormalities in human cancers (1998) (12)
Molecular markers in cancer diagnosis. (1995) (12)
Importance of chromosome 9p loss in human lung cancer. (1995) (12)
Cancer genetics: Two tracks but one race? (1996) (12)
Somatic mitochondrial mutation discovery using ultra-deep sequencing of the mitochondrial genome reveals spatial tumor heterogeneity in head and neck squamous cell carcinoma. (2019) (12)
Ranpirnase Eradicates Human Papillomavirus in Cultured Cells and Heals Anogenital Warts in a Phase I Study (2017) (12)
Molecular Profiling Associated with Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2)-Mediated Carcinogenesis in Gastric Cancer. (2021) (12)
Phospho-DeltaNp63alpha/NF-Y protein complex transcriptionally regulates DDIT3 expression in squamous cell carcinoma cells upon cisplatin exposure. (2010) (12)
Correction: Expression of Aquaporin 5 (AQP5) Promotes Tumor Invasion in Human Non Small Cell Lung Cancer (2008) (11)
Clinical and public health research using methylated DNA Immunoprecipitation (MeDIP): A comparison of commercially available kits to examine differential DNA methylation across the genome (2012) (11)
Epigenetic Inactivation of RASSF 1 A in Head and Neck Cancer 1 (2003) (11)
Chemo brain or tumor brain - that is the question: the presence of extracranial tumors profoundly affects molecular processes in the prefrontal cortex of TumorGraft mice (2017) (11)
Comparative mutational landscape analysis of patient-derived tumour xenografts (2017) (11)
Epigenetic silencing of S100A2 in bladder and head and neck cancers (2015) (11)
Prenatal exposure to tobacco smoke leads to increased mitochondrial DNA content in umbilical cord serum associated to reduced gestational age (2017) (11)
PGP 9 . 5 Methylation in Diffuse-Type Gastric Cancer (2006) (10)
Local Controlled Delivery of Anti-Neoplastic RNAse to the Brain (2009) (10)
Hyperactivation of MEK/ERK pathway by Ca2+/calmodulin‐dependent protein kinase kinase 2 promotes cellular proliferation by activating cyclin‐dependent kinases and minichromosome maintenance protein in gastric cancer cells (2021) (10)
COMMENT ON : DISTINGUISHING SECOND PRIMARY TUMORS FROM LUNG METASTASES IN PATIENTS WITH HEAD AND NECK SQUAMOUS CELL CARCINOMA. AUTHORS' REPLY (1998) (10)
JAK3 Variant, Immune Signatures, DNA Methylation, and Social Determinants Linked to Survival Racial Disparities in Head and Neck Cancer Patients (2019) (10)
Proteomic Changes in Oral Keratinocytes Chronically Exposed to Shisha (Water Pipe). (2019) (9)
Targeting human 8-oxoguanine DNA glycosylase to mitochondria protects cells from 2-methoxyestradiol-induced-mitochondria-dependent apoptosis (2008) (9)
Growth of malignant extracranial tumors alters microRNAome in the prefrontal cortex of TumorGraft mice (2017) (9)
Colorimetric approach to high-throughput mutation analysis. (2005) (9)
MAP2K1 is a potential therapeutic target in erlotinib resistant head and neck squamous cell carcinoma (2019) (9)
PIM1 kinase promotes gallbladder cancer cell proliferation via inhibition of proline-rich Akt substrate of 40 kDa (PRAS40) (2019) (9)
HIST1H2BB and MAGI2 Methylation and Somatic Mutations as Precision Medicine Biomarkers for Diagnosis and Prognosis of High-grade Serous Ovarian Cancer (2020) (9)
Short Communication PGP9.5 As a Candidate Tumor Marker for Non-Small-Cell Lung Cancer (1999) (9)
Inverse Relationship between Human Papillomavirus-16 Infection and Disruptive p53 GeneMutations in Squamous Cell Carcinoma of the Head and Neck (2008) (9)
Promoter methylation of heat shock protein B2 in human esophageal squamous cell carcinoma. (2011) (9)
Establishment and characterization of a platinum- and paclitaxel-resistant high grade serous ovarian carcinoma cell line (2017) (8)
Identification of potential biomarkers of head and neck squamous cell carcinoma using iTRAQ based quantitative proteomic approach (2018) (8)
Yes-associated protein 1 regulates the stability of DeltaNp63alpha. (2010) (8)
Doublecortin-Like Kinase 1 (DCLK1) Is a Novel NOTCH Pathway Signaling Regulator in Head and Neck Squamous Cell Carcinoma (2021) (8)
High-performance detection of somatic D-loop mutation in urothelial cell carcinoma patients by polymorphism ratio sequencing (2016) (7)
Bifunctional immune checkpoint-targeted antibody-ligand traps that simultaneously disable TGFβ enhance the efficacy of cancer immunotherapy (2018) (7)
Uses of DNA methylation in cancer diagnosis and risk assessment (2004) (7)
Screening for clonal genetic alterations. (1995) (7)
Multiomic analysis of oral keratinocytes chronically exposed to shisha (2019) (7)
Advances in Brief The Incidence of p 53 Mutations Increases with Progression of Head and Neck Cancer (2007) (7)
Understanding the MIG6-EGFR Signaling Axis in Lung Tumorigenesis. (2015) (7)
Growth of Triple Negative and Progesterone Positive Breast Cancer Causes Oxidative Stress and Down-Regulates Neuroprotective Transcription Factor NPAS4 and NPAS4-Regulated Genes in Hippocampal Tissues of TumorGraft Mice—an Aging Connection (2018) (7)
Oncogene mutations as intermediate markers (1993) (6)
Functional characterization of alternatively spliced GSN in head and neck squamous cell carcinoma (2018) (6)
Repurposing the FDA-Approved Antiviral Drug Ribavirin as Targeted Therapy for Nasopharyngeal Carcinoma (2020) (6)
Abstract 1018: High-resolution microbiome profiling and genome wide arrays uncover bacteria driven alterations of oncogenic and immune pathways in head and neck cancer patients treated with surgery, chemo-radiation and PD-1 checkpoint blockade therapy (2017) (6)
Whole-Exome Sequencing Analysis of Oral Squamous Cell Carcinoma Delineated by Tobacco Usage Habits (2021) (6)
Mutations in Non-Small Cell Lung Cancer p 53 Frequency of Alcohol Consumption and Cigarette Smoking Increase the Updated (2000) (6)
Epigenomics-based diagnostics. (2010) (6)
I 105 V Polymorphism and Promoter Methylation of the GSTP 1 Gene in Prostate Adenocarcinoma 1 (2002) (6)
Abstract 4891: GULP1, a potential tumor suppressor gene in ovarian tumors and its utility as a biomarker (2010) (5)
Np 63 A UpRegulates the Hsp 70 Gene in Human Cancer (2005) (5)
INSIG2 rs7566605 single nucleotide variant and global DNA methylation index levels are associated with weight loss in a personalized weight reduction program (2017) (5)
Advancing toward a molecular characterization of polymorphous low grade adenocarcinoma. (2017) (5)
Absence of germline prohibitin mutations in early-onset breast-cancer. (1993) (5)
Two tracks but one race? Cancer genetics. (1996) (5)
Abstract 4097: Integrative analysis of epigenetic and transcriptional alterations in head and neck squamous cell carcinomas (2012) (5)
Chronic shisha exposure alters phosphoproteome of oral keratinocytes (2019) (5)
Regulation of p53 Family Member Isoform Δ Np63 α by the Nuclear Factor- κ B Targeting Kinase I κ B Kinase β (2010) (5)
Advances in Brief O 6-Methylguanine-DNA Methyltransferase Promoter Hypermethylation Shifts the p 53 Mutational Spectrum in Non-Small Cell Lung Cancer 1 (2001) (5)
A robust and interpretable gene signature for predicting the lymph node status of primary T1/T2 oral cavity squamous cell carcinoma (2021) (5)
Molecular alterations in oral cancer using high-throughput proteomic analysis of formalin-fixed paraffin-embedded tissue (2021) (4)
miRNA and proteomic dysregulation in non-small cell lung cancer in response to cigarette smoke (2017) (4)
Developing Oncology Drugs Using Virtual Patients of Vascular Tumor Diseases (2011) (4)
Abstract 4512: Doublecortin-like kinase 1 (DCLK1) correlates with Notch pathway signaling, controls metastatic characteristics in head and neck cancer (2018) (4)
D Np63 a Confers Tumor Cell Resistance to Cisplatin through the AKT1 Transcriptional Regulation (2011) (4)
Comparative microsatellite analysis in discerning origin of disseminated tumor: the case of a patient with malignant ascites and a history of multiple tumors. (1999) (4)
Secretome analysis of oral keratinocytes chronically exposed to shisha. (2019) (4)
Molecular alterations in oral cancer between tobacco chewers and smokers using serum proteomics. (2021) (4)
Le dépistage du cancer (1996) (4)
Prognostic biomarkers in patients with human immunodeficiency virus‐positive disease with head and neck squamous cell carcinoma (2017) (4)
Proteomic Alterations Associated with Oral Cancer Patients with Tobacco Using Habits. (2021) (3)
Associated with p 53 Mutations in Non-Small Cell Lung Cancer Microsatellite Instability at Selected Tetranucleotide Repeats Is Updated (2000) (3)
Prognostic implication of p53 mutations in HNSCC: Results of Intragroup margin study (E4393). (2006) (3)
Correction: Association of Promoter Methylation of VGF and PGP9.5 with Ovarian Cancer Progression (2013) (3)
Precision health diagnostic and surveillance network uses S gene target failure (SGTF) combined with sequencing technologies to track emerging SARS‐CoV‐2 variants (2021) (3)
Corrigendum: CDC91L1 (PIG-U) is a newly discovered oncogene in human bladder cancer (2004) (3)
Tyrosine Phosphorylation Profiling Revealed the Signaling Network Characteristics of CAMKK2 in Gastric Adenocarcinoma (2022) (3)
TAp63gamma regulates hOGG1 and repair of oxidative damage in cancer cell lines. (2007) (3)
Distal nephron renal tumors (1996) (3)
Role of the NOTCH Signaling Pathway in Head and Neck Cancer (2018) (3)
Absence of intragenic mismatch mutations in small cell lung cancers with microsatellite instability (1999) (3)
NMDA receptor type 2A at 16p13 is epigenetically inactivated in human colorectal carcinoma (2006) (3)
Milk derived colloid as a novel drug delivery carrier for breast cancer (2015) (3)
TAp63γ regulates hOGG1 and repair of oxidative damage in cancer cell lines (2007) (3)
Feasibility of Quantitative PCR-Based Saliva Screening of HPV for Head and Neck Cancer (2004) (2)
Abstract 152: MicroRNAs in head and neck squamous cell carcinoma (2011) (2)
Signaling alterations in oral keratinocytes in response to shisha and crude tobacco extract. (2020) (2)
TIMP3 Promoter Methylation is an Independent Prognostic Factor for Bladder Cancer (2009) (2)
Advances in Brief Inherited p 53 Gene Mutations in Breast Cancer 1 (2006) (2)
FluorescenceVisualization in Oral Neoplasia : Shedding Light on an Old Problem 55 Commentary on Poh et al . , p . 6716 (2006) (2)
Epigenetic Silencing of HOPX Promotes Cancer Progression (2012) (2)
Medina et al., “Genetic and Epigenetic Screening for Gene Alterations of the Chromatin‐Remodeling Factor, SMARCA4/BRGI, in Lung Tunors”. Genes Chromosomes Cancer 2004; 41:170–177 (2005) (2)
Abstract 2960: DNA promoter hypermethylation of genes as potential diagnostic and prognostic biomarkers for ovarian cancer (2015) (2)
miRNA profiling of bladder cells chronically exposed to cigarette smoke condensate and its vapor (2017) (2)
Using a Novel Computer Technology for Tailoring Targeted and Chemotherapeutic Drug Schedules to the Individual Patient (2006) (2)
TUMOR PROTEIN P63/NUCLEAR FACTOR KAPPA B FEEDBACK LOOP IN REGULATION OF CELL DEATH (2011) (2)
Temporal inactivation of p16 (CDKN2, INK4A, MTS-1) tumor suppressor gene: Is p 16 the gatekeeper gene of head and neck squamous cell carcinoma? (1997) (2)
Expression of GULP1 in bronchial epithelium is associated with the progression of emphysema in chronic obstructive pulmonary disease. (2017) (2)
Identification of the Site of Origin of Unknown Primary Squamous Cell Carcinoma of the Head and Neck Using Microsatellite Analysis (1997) (2)
High frequency of mitochondrial DNA mutations in breast cancer: potential application for cancer detection (2001) (2)
Abstract PR6: Integrated genomic and epigenomic deep sequencing analyses reveal head and neck cancer survival disparities associated to alterations in the PAX, NOTCH1 and TP53 pathways (2014) (2)
Microsatellite deoxyribonucleic acid analysis to detect bladder cancer in bladder exstrophy. (1998) (2)
Abstract 4943: Engulfment gene GULP1 is a functional tumor suppressor through influencing TGF-β pathway and is silenced by promoter methylation in urothelial carcinoma (2015) (2)
Detection and Quantitation of Human Papillomavirus DNA in the Plasma of Patients with Cervical Carcinoma 1 (2002) (2)
Guest Reviewer (2000) (2)
Growth of Malignant Non-CNS Tumors Alters Brain Metabolome (2018) (2)
Abstract A28: Enrolling African Americans into a cancer-related biobank (2015) (2)
Lack of BRCA2 Alterations in Primary Head and Neck Squamous Cell Carcinoma (1997) (2)
Gene mutations aid cytologic screening of cancer (1993) (2)
Tetranucleotide repeat polymorphism in RAF1. (1994) (2)
Mouse clinical trials of pancreatic cancer: Integration of PDX models with genomics to improve patient outcomes to chemotherapeutics (2016) (2)
Erratum: Expression status and prognostic significance of mammalian target of rapamycin pathway members in urothelial carcinoma of urinary bladder after cystectomy (Cancer (2010) 116 (5517-26)) (2011) (2)
Correction: Targeting focal adhesion kinase overcomes erlotinib resistance in smoke induced lung cancer by altering phosphorylation of epidermal growth factor receptor (2021) (1)
Correction: Association of Promoter Methylation of VGF and PGP9.5 with Ovarian Cancer Progression (2013) (1)
Smokers and Nonsmokers Chromosomal Alterations in Lung Adenocarcinoma from Updated (2001) (1)
Changes in CpG islands methylation patterns during ductal breast carcinoma progression. (2008) (1)
Aquaporin 5 (AQP5) is a novel signaling molecule triggering Ras/ERK/retinoblastoma (Rb) signaling pathway in colon cancer cell lines (2007) (1)
Diagnosis of recurrent bladder cancer by microsatellite analysis of the urine sediment (MAUS) (2000) (1)
DNA of Patients with Lung Cancer Methylation Analysis in Tumor Tissue , Serum , and Plasma Quantitative Adenomatous Polyposis Coli Promoter Updated (2002) (1)
Erratum: The TGFβ-miR200-Mig6 pathway orchestrates the EMT-associated kinase switch that induces resistance to EGFR inhibitors (Cancer Research (2014) 74 (3995-4005)) (2014) (1)
Abstract LB-247: Early detection of gastric cancer using global and gene-specific promoter DNA methylation in endoscopic biopsies (2017) (1)
Abstract 3219: A patient-centric repository of PDX models for translational oncology research (2015) (1)
Quantitative RARβ2 Hypermethylation (2004) (1)
Abstract 3640: Validation of qBiomarker as an accurate and efficient mutation detection method in a comprehensive analysis of patient-derived tumor xenografts (2016) (1)
Identification of AIM1 as a Hypermethylation-Inactivated Tumor Suppressor Gene in HNSCC (2004) (1)
Abstract 3443: Doublecortin-like kinase 1 (DCLK1) is novel Notch pathway signaling regulator in HNSCC (2019) (1)
Multi-Omics Analysis to Characterize Cigarette Smoke Induced Molecular Alterations in Esophageal Cells (2020) (1)
Abstract 4703: Mitochondrial DNA mutations affect respiratory complex-I in never-smoker lung cancer patients and contribute to lung cancer cell growth (2011) (1)
144 POSTER Novel Virtual Ptient technology for predicting response of breast cancer and mesenchymal chondrosarcoma patients to mono- and combination therapy by cytotoxic and targeted drugs (2006) (1)
Hypermethylation Is Associated with Higher Tumor Stage in Prostate Cancer (2005) (1)
Macrophage migration inhibitory factor - a therapeutic target in gallbladder cancer (2015) (1)
Proteomic and phosphoproteomic profiling of shammah induced signaling in oral keratinocytes (2021) (1)
Molecular analysis of effectiveness of Mohs' surgical technique (1996) (1)
Response to ‘MMTV‐related env sequences in human breast tumors’ (2003) (1)
Abstract A016: NOG-EXL mice have superior immune cell engraftment and lineage development in the human immune system (HIS) model, the ImmunoGraft (2018) (1)
Prevalence of BRAF Mutations in Thyroid Cancer: Genetic Evidence for Constitutive Activation of the RET/ PTC-RAS-BRAF Signaling Pathway in Papillary Thyroid Carci (2017) (1)
Effect of p53 overexpression and K-ras gene mutations on survival in patients with primary sclerosing cholangitis-associated cholangiocarcinoma (1998) (1)
Inactivation in Lung Squamous Cell Carcinomas Impairs STAT 3 and Promotes Malignant Invasion (2015) (1)
Abstract 2482: Key tumor suppressor genes inactivated by promoter methylation and somatic mutations in head and neck cancer (2014) (1)
How to Achieve Therapeutic Response in Erlotinib-Resistant Head and Neck Squamous Cell Carcinoma? New Insights from Stable Isotope Labeling with Amino Acids in Cell Culture-Based Quantitative Tyrosine Phosphoproteomics. (2021) (1)
Testican 1 (SPOCK1) and protein tyrosine phosphatase, receptor type S (PTPRS) show significant increase in saliva of tobacco users with oral cancer (2018) (1)
Microsatellite analysis of 9p2i in primary uveal melanoma (1997) (1)
Abstract 5031: A humanized mouse model for translational assessment of targeted immune checkpoint blockade (2015) (1)
A Novel pl6INK4ATranscript1 (1995) (1)
Predicting Cancer Following a Diagnosis of High-Grade Prostatic Intraepithelial Neoplasia on Needle Biopsy: Data on Men With More Than One Follow-Up Biopsy (2001) (1)
Betel-associated Oral Cancers from Papua New Guinea Are Infrequent in p 53 Mutations in the Conserved Regions of Updated (2016) (0)
Abstract 5035: MDB-seq screening of muscle-invasive urothelial carcinoma revealed unpredicted novel tumor suppressor genes (2016) (0)
Abstract B06: Repositioning the FDA-approved antiviral drug ribavirin as targeted therapy for nasopharyngeal carcinoma (2019) (0)
Human Cancer Biology Integrated , Genome-Wide Screening for Hypomethylated Oncogenes in Salivary Gland Adenoid Cystic Carcinoma (2011) (0)
Abstract A14: Molecular fidelity of patient derived xenograft (PDX) models to original human tumor and to the cancer genome atlas (TCGA) (2015) (0)
Note of concern. (2012) (0)
Abstract 4939: Testicular Germ Cell Tumors: Could Aberrant Promoter Methylation differentiate Seminomas from Non-Seminomas (2010) (0)
195 A humanized mouse model for preclinical testing of molecules targeting immune checkpoints (2014) (0)
Abstract 1363: Epigenetic inactivation of VGF in urothelial cell carcinoma and its potential as a non-invasive biomarker using urine (2014) (0)
Abstract 1551:GULP1is an epigenetically altered and functional tumor suppressor in urothelial carcinoma through regulation of Nrf2-Keap1 signaling axis (2017) (0)
Abstract 527: Analysis of the interaction between microRNAs and Notch pathway members in HNSCC (head and neck squamous cell carcinoma) (2014) (0)
Detection of bladder cancer recurrence by microsatellite analysis of the urine sediment (MAUS) (1998) (0)
Abstract 4192: CervicalMethDx: A precision DNA methylation test to identify advanced disease risk in cervical cancer screening algorithms (2023) (0)
Abstract 5231: Prognostic significance of miR-23b and miR-31 expression in non-small-cell lung cancer (2014) (0)
Abstract B25: KRAS mutation status is associated with enhanced dependency on purine biosynthesis and related pathways in non small cell lung cancer cells (2014) (0)
Abstract 3172: Methylation portraits discriminate between hepatocellular carcinoma cases and controls (2011) (0)
Loss of Heterozygosity on 13q is Associated with Decreased Survival Rates in Head and Neck Cancer Patients (1997) (0)
In Vivo Gene Therapy with p16 Adenovirus for Head and Neck Squamous Cell Carcinoma (1997) (0)
ANALYSS OF SPUTUM BY AMPLFICATION AND DETECTION OF MUTANT NUCLEIC ACID SEQUENCES (2017) (0)
Abstract A12: Web-based tools for visualization of the Human Papilloma Virus genome dynamics: A computational approach to cancer prevention and control (2012) (0)
A novel class of Ribosome Modulating Agents (RMAs) targets ribosome heterogeneity in a subset of colorectal cancers (2022) (0)
Integrated multi-omics analysis reveals potential mechanisms of acquired resistance to erlotinib in head and neck cancer cells (2017) (0)
Erratum: CDC91L1 (PIG-U) is a newly discovered oncogene in human bladder cancer (Nature Medicine (200) 10 (7-381)) (2004) (0)
Real-Time Quantitative PCR Demonstrates Low Prevalence of Human Papillomavirus Type 16 in Premalignant and Malignant Lesions of the Oral Cavity 1 (2002) (0)
Abstract 4799: Promoter methylation of leukemia inhibitory factor receptor gene in colorectal carcinoma (2011) (0)
Session 2: Molecular Diagnostics (2004) (0)
Towards personalized medicine: Establishment and in vivo characterization of a low passage tumor xenograft tumor predictive of clinical response (2007) (0)
Activationof the NOTCH Pathway inHeadandNeckCancer (2014) (0)
High Resolution Mapping of a Minimal Region of Deletion on Chromosomal Arm 3p24 in Uveal Melanoma (2002) (0)
Mig6 is upregulated in an erlotinib resistant cell line which suppresses EGFR phosphorylation. (2013) (0)
Temporal Inactivation of pl6 (CDKN2, INK4A, NITS-1) Tumor Suppressor Gene: Is p16 the Gatekeeper Gene of Head and Neck Squamous Cell Carcinoma? (1997) (0)
Methylation pattern of multiple genes in urine sediment DNA from bladder cancer cases and controls by high throughput quantitative methylation specific PCR (QMSP) (2005) (0)
Loss of heterozygosity and mutational analysis in 7q22-31.1 in HNSCC (1999) (0)
PIM1 kinase promotes gallbladder cancer cell proliferation via inhibition of proline-rich Akt substrate of 40 kDa (PRAS40) (2019) (0)
Proteomic profiling of gallbladder cancer secretome – a source for circulatory biomarker discovery (2013) (0)
Advances in Brief Gene Promoter Hypermethylation in Tumors and Serum of Head and Neck Cancer Patients 1 (2000) (0)
Erratum: RACK1 and stratifin target ΔNp63α for a proteasome degradation in head and neck squamous cell carcinoma upon DNA damage (Cell Cycle (2006) 3, (1285-1295)) (2007) (0)
Cancer Patients in Tumors and Saliva of Head and Neck Protein Kinase Death-associated , and-Methylguanine-DNA-methyltransferase 6 O , p 16 Promoter Hypermethylation Patterns of Updated (2001) (0)
Abstract 1505: Targeted sequencing for the assessment of intratumor heterogeneity (2014) (0)
First on March 9 , 2010 as 10 . 1158 / 0008-5472 . CAN-09-3427 (2010) (0)
Abstract 2703: Loss of dependence on EGFR signaling by upregulation of Mig6 confers drug resistance to erlotinib (2010) (0)
Abstract 2781: Champions TumorGraft™ models possess PIK3CA mutations - A great tool to explore the PI3K/AKT pathway. (2013) (0)
NMDA receptor 2B promoter methylation predicts poor prognosis in esophageal squamous cell carcinoma (2007) (0)
Abstract 570: High-resolution microbiome profiling of 16SrRNA sequencing data, Microbiome Arrays, and expression arrays identifies differential bacterial communities in head and neck cancer patients treated with surgery, chemo-radiation, and PD-1 checkpoint blockade therapy (2018) (0)
Abstract 4410: KRAS mutation status is associated with enhanced dependency on purine biosynthesis and related pathways in non small cell lung cancer cells (2014) (0)
Molecular and Cellular Pathobiology Activationof the NOTCH Pathway inHeadandNeckCancer (2014) (0)
Abstract B52: Promoter methylation, stage at presentation, and neighborhood-level effects are linked to survival disparities in HNSCC patients (2016) (0)
Abstract 5451: Arsenic induced altered pathways in bladder cancer (2012) (0)
Abstract 6268: Use of the anti-viral drug ribavirin as a radiosensitizing agent in nasopharyngeal carcinoma (2020) (0)
Corrigendum (2015) (0)
High-performance detection of somatic D-loop mutation in urothelial cell carcinoma patients by polymorphism ratio sequencing (2016) (0)
David Sidransky (2002) (0)
Abstract 2205: Integrated next generation sequencing and patient-derived xenografts to personalized cancer treatment. (2013) (0)
Abstract 2792: Characterization of spontaneous in vivo cachexia models in Champions TumorGraft™ models. (2013) (0)
Abstract LB-440: Global DNA hypomethylation is independently associated with clinical diagnosis of gastric cancer, inflammation severity, and metaplasia (2011) (0)
Abstract 4671: Tumor Suppressive Role of HOP (homeobox only protein) Gene in Gastric Cancer (2010) (0)
433 Anti-cancer activity of onconase, a cytotoxic amphibian ribonuclease, in combination with standard of care agents in non-small cell lung tumorgraft models (2010) (0)
Microsatellite-based detection of bladder cancer by analysis of urine using fast capilary array electrophoresis and fluorescent primers (1997) (0)
Detección de células neoplásicas mediante técnicas de ADN y su uso como marcador en la práctica clínica oncológica (1999) (0)
Abstract 4466: GULP1 is a potential tumor suppressor that modulates chemo-resistance through regulation of Nrf2-Keap1 signaling axis in urothelial carcinoma (2016) (0)
Abstract 813: Doublecortin-like kinase 1 (DCLK1) and NOTCH1 pathways lead to poor prognosis in HNSCC (2020) (0)
The oncogenic property of Aquaporin 5 (AQP5): Human AQP5 plays a role in proliferation of chronic myelogenous leukemia (CML) cells. (2007) (0)
Patients with Renal Cancer Multiple Genes in the Tumor , Urine , and Serum DNA of Quantitative Detection of Promoter Hypermethylation of Updated (2004) (0)
Novel molecular detection approaches in various cancers (2001) (0)
Abstract 4189: Utilization of Champions Tumorgraft™ models to identify putative biomarkers and signatures of response (2011) (0)
Corrigendum to: Milk derived colloid as a novel drug delivery carrier for breast cancer (Cancer Biology & Therapy, 16, 8, (1184-93), 10.1080/15384047.2015.1056416) (2015) (0)
Abstract 1190: Multifactorial biological processes govern engraftment of patient-derived tumor tissue in immunodeficient mice (2014) (0)
Abstract 1329: Personalizing gastrointestinal cancer treatment by the utilization of TumorGraft™ technology (2012) (0)
Abstract 1648: ImmunoGraft® platform for the evaluation of Immuno-Oncology agents in PDX tumors models (2017) (0)
Focal oral mucinosis (2005) (0)
Delineating miRNA profile induced by chewing tobacco in oral keratinocytes (2017) (0)
ABERRANT GENE PROMOTER HYPERMETHYLATION IN THE URINE AS A BIOMARKER OF ATN DURING KIDNEY (2006) (0)
466 Ranpirnase: A potential microbicide with broad-spectrum antiviral profile (HIV, HSV, HPV) (2018) (0)
Abstract 4382: Relative expression of miR200 microRNAs and ERBB family negative regulator Mig6 in estimation of EMT status and erlotinib sensitivity (2014) (0)
Tumor and Stem Cell Biology D Np 63 a Confers Tumor Cell Resistance to Cisplatin through the AKT 1 Transcriptional Regulation (2011) (0)
Detection of mitochondrial DNA mutations in head and neck cancers (2006) (0)
Molecular Detection of Head and Neck Cancer (2003) (0)
AssociationBetween BRAFV600EMutationand MortalityinPatientsWithPapillaryThyroidCancer (2013) (0)
Abstract 3983: Highly sensitive detection of MYB-NFIB fusion transcripts in adenoid cystic carcinoma (2016) (0)
Abstract 4662: Epigenetic conversion on p53 pathway in human cancer: The clinical potential of p53 mutation status as a predictive biomarker for drug sensitivity by epigenetic treatment. (2013) (0)
Bifurcated Tumor Progression Pathway Allelotype of Posterior Uveal Melanoma : Implications for a (2013) (0)
University of Groningen 16S rRNA amplicon sequencing identifies microbiota associated with oral cancer, Human Papilloma Virus infection and surgical treatment Guerrero-Preston, (2016) (0)
Abstract 655: Genome-wide methylation profiling and the PI3K-AKT pathway analysis associated with smoking in urothelial cell carcinoma . (2013) (0)
Abstract LB-68: Identification of circulating HPV DNA in urine with a dual sequence capture approach. (2013) (0)
Detection of clonal mitochondrial DNA mutation in airway mucosa of follow-up lung cancer patients (2007) (0)
Abstract 666: Validation of nucleolar protein 4 as a novel methylated tumor suppressor gene in head and neck cancer. (2013) (0)
TAp63γ regulates hOgg1 (2007) (0)
Abstract A8: The ImmunoGraft: A humanized mouse model for translational assessment of immunotherapy in solid tumors (2015) (0)
A novel class of Ribosome Modulating Agents (RMAs) target MYC driven SCLC and synergize with DNA intercalating agents (2022) (0)
Colorectal Cancer Patients Molecular Detection of Genetic Alterations in the Serum of Updated (2006) (0)
Advances in Brief Np 63 and TAp 63 Regulate Transcription of Genes with Distinct Biological Functions in Cancer and Development 1 (2003) (0)
Effect of different regimens of chemotherapy on stem-cell marker expression. (2007) (0)
Erratum: Quantitative assessment of promoter methylation profiles in thyroid neoplasms (Journal of Clinical Endocrinology and Metabolism (2005) 90 (4011-4018)) (2006) (0)
Abstract 1187: The Champions TumorGraft Bank: A demographically-rich repository of preclinical TumorGraft models (2014) (0)
Abstract 1384: Promoter methylation of tumor suppressor genes in convalescent saliva samples from patients with head and neck squamous cell carcinoma (2014) (0)
Method of detecting prostate cancer. (2002) (0)
Abstract 4035: Inactivation of the putative tumor suppressor gene AGTR1 by promoter hypermethylation in primary human cancer (2012) (0)
SH3GL2 is frequently deleted in non-small cell lung cancer and downregulates tumor growth by modulating EGFR signaling (2012) (0)
Abstract IA03: Patient-derived xenografts as translational tools to predict patient responses to oncology therapy (2016) (0)
Abstract 2202: Integrated screening for epigenetically controlled tumor suppressor genes and oncogenes in salivary adenoid cystic carcinoma (2010) (0)
Patient-derived xenograft (PDX) models of BRCA-deficient and BRCA-like ovarian tumors reflect clinical responses to PARP inhibition (2016) (0)
75 POSTER Establishment, validation, and in vivo evaluation of tumor explant models of adenoid cystic carcinoma: effects of FDA-approved and candidate therapies in human ACC xenografts (2008) (0)
Abstract 1836: Patient-derived xenograft (PDX) models expressing HER2 reflect clinical responses to targeted HER2 inhibition (2017) (0)
Clusterin Is a Gene-Speci fi c Target of microRNA-21 in Head and Neck Squamous Cell Carcinoma (2014) (0)
Abstract 5574: ZNF516 and FKBP6 promoter hypermethylation as a potential companion diagnostic panel for HPV-positive and inconclusive-Pap women (2012) (0)
Abstract 4041: Identification of GNG7 as an epigenetically silenced gene in head and neck cancer by gene expression profiling (2012) (0)
Abstract 1533: 16S rRNA saliva analysis unveils differences in the head and neck squamous cell carcinoma microbiome before and after surgical resection (2015) (0)
Serial Analysis of Gene Expression in Non-Small Cell Lung Cancer1 (1998) (0)
Abstract A018: Patient-derived xenograft (PDX) models of NSCLC reflect clinical drug responses and predict effective treatments for patients (2018) (0)
Abstract B43: Germline and somatic mutations, immune signatures, and epigenetic alterations linked to neighborhood determinants of health differ in Black and non-Latino White head and neck cancer patients (2018) (0)
Role of protein kinase N2 (PKN2) in cigarette smoke-mediated oncogenic transformation of oral cells (2018) (0)
Abstract 963: Epigenetic silencing of cancer-specific methylation may converge on therapeutic targets on human cancers (2012) (0)
Book Review Cellular Cancer Markers (Contemporary Biomedicine.) Edited by Carleton T. Garrett and Stewart Sell. 484 pp. Totowa, N.J., Humana Press, 1995. $125. 0-89603-210-8 (1995) (0)
APromoter Methylation Pattern in the N-Methyl-D-Aspartate Receptor 2 BGene Predicts Poor Prognosis in Esophageal Squamous Cell Carcinoma (2007) (0)
166 Biomarkers and personalized models in oncology drug development (2009) (0)
Abstract 811: Induction of stem-like cells with malignant properties by chronic exposure of immortalized normal human urothelial cell line to arsenic (2015) (0)
Abstract B1-62: Bumphunting analysis identifies PAX5 promoter methylation and p53 somatic mutations in genomic instability pathways linked to very poor survival in head and neck cancer (2015) (0)
Abstract 4284: Evaluation of cancer-related mutations in tumorgraft models (2014) (0)
Abstract 5067: Neurofilament heavy polypeptide regulates the Akt-β-catenin pathway in human esophageal squamous cell carcinoma (2010) (0)
Abstract 5379: Recurrent inactivation of PARD3, a polarity-related gene, in squamous cell carcinomas of the lung. (2013) (0)
R032: Cancer-Specific Hypermethylation of Tazarotene-Induced Gene 1 (TIG1) (2003) (0)
DAP-K HYPERMETHYLATION IN CERVICAL SCRAPINGS DISTINGUISHES CERVICAL CANCER CASES FROM CONTROLS (2003) (0)
Abstract 734: Improved detection of salivary glands’ RNA markers in saliva samples (2017) (0)
Unexpected heterogeneity in oropharyngeal squamous cell tumors (2023) (0)
Abstract 4667: mtDNA sequencing in HNSCC as a measurer of intratumoral heterogeneity and lymph node metastasis (2017) (0)
Abstract 5171: EGFR induction of SOX9 is required in a cellular migration program induced by urothelial injury and maintained in cancer (2010) (0)
573 Copy Number Variation Analysis for Identification of Novel Disease-related Regions in Bladder Cancer (2012) (0)
Abstract 1217: Development of a spontaneous in vivo cachexia model using the Champions TumorGraft™ platform (2014) (0)
Slow development impedes the uptake of diagnostics (2008) (0)
The KRAS-variant is a Biomarker of Cetuximab Response and Altered Immunity in Head and Neck Cancer: NRG Oncology/RTOG 0522 (2016) (0)
1573PDPATIENT-DERIVED XENOGRAFTS ACCURATELY CAPTURE CLINICAL RESPONSES TO TREATMENT. (2014) (0)
Establishment and characterization of a platinum- and paclitaxel-resistant high grade serous ovarian carcinoma cell line (2017) (0)
Abstract 2458: Spatial genomic heterogeneity of multifocal bladder cancer (2017) (0)
Abstract 4802: Cat eye syndrome chromosome region, candidate 1 (CECR1) is overexpressed and hypomethylated in salivary gland adenoid cystic carcinoma (2011) (0)
270 Human primary colon tumorgraft models possess similar clinical response characteristics (2010) (0)
Abstract 84: OGDHL is epigenetically silenced and suppresses growth in human cervical cancer (2011) (0)
S7. Cancer prevention: Scientific anticipations and clinical hopes (2008) (0)
Abstract PR-4: From mice to men: Guiding cancer treatment through Personalized Tumorgraft™ models results in prolonged clinical responses in patients with refractory advanced cancers and discovery of novel predictive biomarkers (2009) (0)
Cigarette smoke and chewing tobacco alter expression of different sets of miRNAs in oral keratinocytes (2018) (0)
Abstract 6131: Extracellular vesicles containing p53 of xenogeneic origin as a therapeutic strategy (2023) (0)
NMDAR2B is hypermetylated in ESCC (2006) (0)
Development of novel high throughput microsatellite technology for detection of bladder cancer (2001) (0)
Abstract 4841: Combining array-based approaches for the identification of candidate loci and related molecules in non-small lung cancer (NSCLC) (2011) (0)
Abstract AS15: DNA promoter hypermethylation of HIST1H2BB as a diagnostic and prognostic biomarker for ovarian cancer (2015) (0)
Abstract B02: DNA promoter methylation of HIST1H2BB as a potential early detection biomarker to reduce ovarian cancer disparities in the United States (2015) (0)
Abstract PR3: Exome sequencing of head and neck squamous cell carcinoma reveals a higher frequency of mutations in TP53 among African Americans (2011) (0)
Highly sensitive mtDNA sequencing in Head and neck squamous cell carcinoma as a marker of intratumoral heterogeneity and lymph node metastasis (2018) (0)
406 POSTER Establishment and in vivo evaluation of two human sarcoma xenograft models: results of tumor growth and chemotherapy sensitivity in models of mesenchymal chondrosarcoma (MCS) and leiomyosarcoma (LMS) (2006) (0)
Abstract 690: Potential biomarkers for the prediction of urothelial cell carcinoma recurrence. (2013) (0)
Abstract B11: Viral and host gene methylation in liquid prep: novel molecular screening and triage tools to reduce cervical cancer disparities (2016) (0)
Abstract 2798: Champions TumorGraft™ models represent oncology clinical trial populations. (2013) (0)
Abstract 2424: The in-parallel whole-genome ChIP-Seq analysis of primary tissues, patient derived xenografts, and cancer cell lines from HPV-relative HNSCC samples (2017) (0)
Abstract 558: Mutational heterogeneity related to neoadjuvant therapy response in muscle invasive urothelial cell carcinoma revealed by whole-exome sequencing (2014) (0)
Patient-derived xenografts effectively capture patient clinical responses to oncology therapy (2016) (0)
Abstract #3029: Diet and lifestyle factor associations with CpG island methylation in high-risk population (2009) (0)
Abstract 4193: Exposure to arsenic and miRNA deregulation: a potential non-invasive screening tool for urothelial cell carcinoma. (2013) (0)
Abstract 3940: Inactivation of the PARD3 gene is a recurrent event in lung squamous cell carcinomas and affects STAT3 activity and tumor invasiveness (2015) (0)
Importance of Chromosome 9 p Loss in Human Lung Cancer (2005) (0)
Correction: Association of Promoter Methylation of and with Ovarian Cancer Progression. (2013) (0)
Abstract 1860: An epigenetic biomarker panel for detection of early stage lung cancer using serum DNA (2014) (0)
Clinical and Prognostic Significance of the Eighth Edition Oral Cancer Staging System (2022) (0)
Abstract LB-410: A single nucleotide polymorphism in human PIGK gene associates with low PIGK expression in colorectal cancer patients (2010) (0)
Title: Mitochondrial DNA Mutation in Normal Margins and Tumors of Recurrent HNSCC Patients (2010) (0)
CEBP FOCUS Biomarkers for Lung Cancer Screening and Detection (2020) (0)
R036: Evaluation of the Role of the Epstein-Barr Virus in 300 Primary SCCHN (2003) (0)
Abstract P5-05-13: Inhibition of NOTCH signaing with g-secretase inhibitor AL101 contributes to overcome resistance against HER2-targeted therapy in HER2 amplified breast cancer cells (2020) (0)
Abstract B30: A phase 1 open label, dose-escalation trial evaluating the safety and tolerability of EF-022, macrophage activator, in subjects with advanced solid malignancies (2015) (0)
Onconase, a cytotoxic ribonuclease, in combination with standard of care agents in non-small cell lung tumorgraft models. (2011) (0)
10:30 AM: Prognostic Implication of Loss of Heterozygosity of 4q in Head and Neck Squamous Cell Carcinoma (1996) (0)
Genomic characterization of immune targets in patient-derived xenograft models for translational assessment of immunotherapy (2016) (0)
Abstract 2793: Development of an androgen-dependent prostate Champions TumorGraft™ cancer model. (2013) (0)
Abstract 829: Down-regulation of insulin-like growth factor-binding protein 7 in cisplatin-resistant non-small cell lung cancer (2012) (0)
A Novel pl 6 INK 4 ATranscript 1 (2006) (0)
Abstract 4899: Identification of epigenomics biomarkers for early detection and progression of cervical carcinogenesis (2010) (0)
Abstract 4728: Genome-wide analysis of genetic alterations in seminoma using high resolution single Nucleotide polymorphism (SNP) arrays (2010) (0)
Investigation of curcumin-mediated signalling pathways in head and neck squamous cell carcinoma (2017) (0)
First Person: David Sidransky, MD (2018) (0)
Abstract 4527: p53-Reactivating Small Molecules Induce Apoptosis in Head and Neck Cancer (2010) (0)
Molecular-based tumor cell screening at the lymph nodes of metastatic colorectal cancer patients predicts recurrence (1999) (0)
Global and gene specific DNA methylation as a screening tool for early detection of liver cancer. (2007) (0)
Abstract B103: Aquaporin 5 (AQP5) is expressed in primary human leukemic cells. (2008) (0)
DETECTION OF CERVICAL CANCER BY QUANTITATIVE PROMOTOR HYPERMETHYLATION ASSAY ON CERVICAL SCRAPINGS (2004) (0)
Abstract 4844: High throughput detection of PRKD1 mutations in salivary gland tumors usingin situmutation detection in tissue microarrays (2015) (0)
Abstract 1674: Humanized mouse models for personalized preclinical testing of monoclonal antibodies targeting immune checkpoints (2014) (0)
Promoter hypermethylation of the neurofilament heavy chain gene in human esophageal cancer (2007) (0)
Abstract 4095: Stimulation of blood based biomarker release in primary tumor models of the head and neck (2012) (0)
Comparison of p53 Mutation Detection and Telomerase Activity for the Molecular Staging of Head and Neck Squamous Cell Carcinoma (1997) (0)
Abstract 1978: Community Genomic Health Promotion Program evaluates precision DNA methylation biomarkers for use in self-testing and collection kits in urine, to increase cervical cancer screening rates among Latina women (2023) (0)
AssociationBetween BRAF V 600 EMutationand MortalityinPatientsWithPapillaryThyroidCancer (2013) (0)
Abstract LB107: A precision DNA methylation test to triage HPV positive women before referral to colposcopy-driven biopsies or ablative treatment in cervical cancer screening clinics worldwide (2023) (0)
Abstract 4474: Functional characterization of alternatively splicedGSNin head and neck cancer (2017) (0)
Advances in Brief Microsatellite instability in Bladder Cancer I (2007) (0)
268: Loss of Heterozygosity (LOH) of Single-Nucleotide Polymorphisms (SNPS) Detected in the Urine of Patients with Bladder Cancer: Correlation with Stage and Clinical Outcome (2004) (0)
PD.222 Correlation between promoterhypermethylation and human papilloma virus in head and neck squamous carcinoma (2005) (0)
Integrated genomics and avatar mouse models for personalized cancer treatment. (2013) (0)
Abstract 5252: Utilization of TumorGraft technology for personalized breast cancer treatment (2012) (0)
Cancer Biology and Signal Transduction KRAS Mutation Status Is Associated with Enhanced Dependency on Folate Metabolism Pathways in Non – Small Cell Lung Cancer Cells (2014) (0)
Abstract 128: Role of {Delta}Np63{alpha} and its effect in cisplatin-mediated chemoresistance (2010) (0)
Loss of Chromosomes 3p, 4q, and 11q is Associated With Radiation Resistance in Patients with Head and Neck Squamous Celt Carcinoma (1997) (0)
000423 ASSESSMENT OF GENE PROMOTER HYPERMETHYLATION FOR DETECTION OF CERVICAL NEOPLASIA, A PILOT STUDY (2005) (0)
Molecular biology of cancer, virus and HLA typing. (1994) (0)
Epigenetic Unsilencing of Uveal Melanoma Genes by 5–Aza–2–Deoxycytidine (2005) (0)
Abstract 3170: Early detection and follow up of head and neck squamous cell carcinoma – A longitudinal serum based biomarker study (2011) (0)
Analysis of the secretomes of oral keratinocytes chronically exposed to smokeless tobacco (2013) (0)
NSD1- and NSD2-damaging mutations define a subset of laryngeal tumors with favorable prognosis (2017) (0)
Abstract LB-25: Regulation of Np63α by IκB kinase-β (2010) (0)
Advances in Brief High Frequency of piÃ 3 ( CDKN 2 / MTS-1 / INK 4 A ) Inactivation in Head and Neck Squamous Cell Carcinoma 1 ' 2 (2006) (0)
Abstract 2750: An epigenetic and immunologic approach to optimize therapy for HNSCC (2018) (0)
Abstract 1892: Identification of differentially methylated genes associated with cetuximab and erlotinib resistance (2012) (0)
Zhong X Hypermethylation in Shistosoma Haematobium infection PLOSone 2013 (2014) (0)
Cigarette smoke induces metabolic reprogramming in lung cells (2017) (0)
IncreasedMitochondrial DNAContent in Saliva Associatedwith Head and Neck Cancer (2005) (0)
Abstract LB-458: Cold plasma selectively affects HNSCC cell lines by non-apoptotic pathways (2012) (0)
R098: Identification of Putative Hypermethylation-Inactivated Tumor Suppressor Genes in HNSCC (2003) (0)
Abstract A25: Establishment and characterization of primary human Biomerk Tumorgraft™ Models: Application to oncology drug development (2009) (0)
Towards personalized medicine: Evaluation of blood and tissue biomarkers for drug sensitivity in a newly established human xenograft model (2006) (0)
Abstract LB-218: Role of ERBB family negative regulator Mig6 in estimating erlotinib responsiveness. (2013) (0)
Moving towards clinically relevant preclinical models: Establishment, molecular characterization and in vivo evaluation of patient-derived low passage human tumor models (2008) (0)
Abstract 2924: Genome-wide microarray platforms uncover novel hypermethylated genes in an oral squamous cell carcinoma case-control study: A phase I preclinical biomarker development study (2010) (0)
Abstract 4947: Homeobox geneHOPXis epigenetically silenced cancer-specifically in colorectal cancer and predicts poor prognosis in stage III colorectal cancer (2010) (0)
TAp63 isoform induces epithelial hyperproliferation in the mice (2007) (0)
Abstract 3420: Discovery of genetic alterations governing sinonasal squamous cell carcinoma tumorigenesis (2018) (0)
Galectin-1 promotes the invasion of bladder cancer urothelia through their matrix milieu (2018) (0)
Reply to “Proteomic alterations of cancer-cell mitochondria: driver or bystander?” (2003) (0)
Inhibitors EMT-Associated Kinase Switch That Induces Resistance to EGFR MIG 6 Pathway Orchestrates the − miR 200 − β The TGF (2014) (0)
Abstract 5765: Promoter DNA methylation patterns in oral, laryngeal, and oropharyngeal anatomical regions are associated with tumor differentiation, nodal involvement, and survival in Latinos (2023) (0)
An accelerated pathway for targeted cancer therapies A well-defined pathway for the accelerated development and approval of targeted cancer therapies and companion diagnostics would reduce uncertainty, improve efficiency in development and provide an effective incentive for developers. (2011) (0)
Microsatellite Instability in Colorectal Cancer Development of International Criteria for the Determination of Instability for Cancer Detection and Familial Predisposition : A National Cancer Institute Workshop on Microsatellite (2006) (0)
Head and Neck Cancer Mutations Increases with Progression of p 53 The Incidence of Updated Version (2007) (0)
Abstract A25: Chromatin structure regulates cancer-specific alternative splicing events in primary HPV-related oropharyngeal squamous cell carcinoma (2020) (0)
Abstract 3910: An integrated genomic and epigenomic approach for identification of novel disease-related regions and genes in bladder cancer progression (2011) (0)
Mitochondrial DNA as a cancer biomarker | NIST (2005) (0)
Abstract A1-50: Genomic and epigenomic alterations in human and high-risk HPV DNA can discriminate normal from cervical dysplasia patients in urine (2015) (0)

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