David Wallach
#52,741
Most Influential Person Now
Israeli biochemist
David Wallach's AcademicInfluence.com Rankings
David Wallachbiology Degrees
Biology
#4241
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#6357
Historical Rank
Biochemistry
#786
World Rank
#891
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Molecular Biology
#915
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#938
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Biology
David Wallach's Degrees
- PhD Biochemistry Tel Aviv University
- Bachelors Chemistry Tel Aviv University
Why Is David Wallach Influential?
(Suggest an Edit or Addition)According to Wikipedia, David Wallach is a full professor at the Department of Biological Chemistry at Weizmann Institute of Science, Israel, laureate of the 2014 Emet Prize for Life Sciences. , and laureate of the 2018 The Paul Ehrlich and Ludwig Darmstaedter Prize.
David Wallach's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 (2018) (3106)
- Involvement of MACH, a Novel MORT1/FADD-Interacting Protease, in Fas/APO-1- and TNF Receptor–Induced Cell Death (1996) (2412)
- Tumor necrosis factor receptor and Fas signaling mechanisms. (1999) (1402)
- MAP3K-related kinase involved in NF-KB induction by TNF, CD95 and IL-1 (1997) (1389)
- Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally. (1998) (1280)
- A Novel Protein That Interacts with the Death Domain of Fas/APO1 Contains a Sequence Motif Related to the Death Domain (*) (1995) (1113)
- The tumour suppressor CYLD negatively regulates NF-κB signalling by deubiquitination (2003) (1045)
- Stabilization of the bioactivity of tumor necrosis factor by its soluble receptors (1992) (865)
- Immunocytochemical analysis of tumor necrosis factor and its receptors in Parkinson's disease (1994) (589)
- Two tumor necrosis factor-binding proteins purified from human urine. Evidence for immunological cross-reactivity with cell surface tumor necrosis factor receptors. (1990) (550)
- Elevated tumour necrosis factor‐alpha (TNF‐α) biological activity in psoriatic skin lesions (1994) (478)
- A tumor necrosis factor-binding protein purified to homogeneity from human urine protects cells from tumor necrosis factor toxicity. (1989) (445)
- The CD95 Receptor: Apoptosis Revisited (2007) (403)
- Programmed necrosis in inflammation: Toward identification of the effector molecules (2016) (402)
- Self-association of the Death Domains of the p55 Tumor Necrosis Factor (TNF) Receptor and Fas/APO1 Prompts Signaling for TNF and Fas/APO1 Effects (*) (1995) (395)
- Caspase-8 Serves Both Apoptotic and Nonapoptotic Roles1 (2004) (390)
- Caspase-8 blocks kinase RIPK3-mediated activation of the NLRP3 inflammasome. (2013) (388)
- Antibodies to a soluble form of a tumor necrosis factor (TNF) receptor have TNF-like activity. (1990) (388)
- Soluble cytokine receptors are present in normal human urine (1989) (379)
- Preferential effect of γ interferon on the synthesis of HLA antigens and their mRNAs in human cells (1982) (361)
- Increased levels of soluble tumor necrosis factor receptors in the sera and synovial fluid of patients with rheumatic diseases. (1992) (353)
- CASH, a Novel Caspase Homologue with Death Effector Domains* (1997) (351)
- Faculty Opinions recommendation of De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling. (2004) (336)
- Induction of Interleukin-8 Synthesis Integrates Effects on Transcription and mRNA Degradation from at Least Three Different Cytokine- or Stress-Activated Signal Transduction Pathways (1999) (335)
- Soluble forms of tumor necrosis factor receptors (TNF‐Rs). The cDNA for the type I TNF‐R, cloned using amino acid sequence data of its soluble form, encodes both the cell surface and a soluble form of the receptor. (1990) (326)
- Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 (2018) (323)
- The death domain: a module shared by proteins with diverse cellular functions. (1995) (322)
- Two interferon mRNAs in human fibroblasts: in vitro translation and Escherichia coli cloning studies. (1980) (321)
- Survival function of the FADD-CASPASE-8-cFLIP(L) complex. (2012) (296)
- Inhibition of Tumor Necrosis Factor Alpha (TNFα) Activity in Rat Brain is Associated with Cerebroprotection after Closed Head Injury (1996) (264)
- TNF stimulates expression of mouse MHC class I genes by inducing an NF kappa B‐like enhancer binding activity which displaces constitutive factors. (1989) (264)
- Cell death induction by receptors of the TNF family: towards a molecular understanding (1997) (252)
- Increased serum levels of soluble receptors for tumor necrosis factor in cancer patients. (1991) (252)
- CD27, a Member of the Tumor Necrosis Factor Receptor Superfamily, Activates NF-κB and Stress-activated Protein Kinase/c-Jun N-terminal Kinase via TRAF2, TRAF5, and NF-κB-inducing Kinase* (1998) (251)
- Cell death induction by TNF: a matter of self control. (1997) (250)
- MLKL, the Protein that Mediates Necroptosis, Also Regulates Endosomal Trafficking and Extracellular Vesicle Generation (2017) (240)
- Receptor-Specific Signaling for Both the Alternative and the Canonical NF-κB Activation Pathways by NF-κB-Inducing Kinase (2004) (229)
- Hsp90 Recognizes a Common Surface on Client Kinases* (2006) (227)
- Interferon-dependent induction of mRNA for the major histocompatibility antigens in human fibroblasts and lymphoblastoid cells. (1982) (218)
- A casein kinase I motif present in the cytoplasmic domain of members of the tumour necrosis factor ligand family is implicated in ‘reverse signalling’ (1999) (208)
- Human neutrophil elastase releases a ligand-binding fragment from the 75-kDa tumor necrosis factor (TNF) receptor. Comparison with the proteolytic activity responsible for shedding of TNF receptors from stimulated neutrophils. (1991) (204)
- Tumor Necrosis Factor (TNF) Receptor Shedding Controls Thresholds of Innate Immune Activation That Balance Opposing TNF Functions in Infectious and Inflammatory Diseases (2004) (201)
- RIG-I RNA helicase activation of IRF3 transcription factor is negatively regulated by caspase-8-mediated cleavage of the RIP1 protein. (2011) (195)
- Caspase-8 deficiency in epidermal keratinocytes triggers an inflammatory skin disease (2009) (180)
- Sensitization and desensitization to lethal effects of tumor necrosis factor and IL-1. (1988) (178)
- Identification of a cell protein (FIP-3) as a modulator of NF-κB activity and as a target of an adenovirus inhibitor of tumor necrosis factor α-induced apoptosis (1999) (177)
- Dual role of the p75 tumor necrosis factor (TNF) receptor in TNF cytotoxicity (1994) (167)
- Tumor necrosis factor induction by Sendai virus. (1986) (162)
- Epstein–Barr virus-transforming protein latent infection membrane protein 1 activates transcription factor NF-κB through a pathway that includes the NF-κB-inducing kinase and the IκB kinases IKKα and IKKβ (1998) (159)
- Variation in serum levels of the soluble TNF receptors among healthy individuals. (1992) (157)
- Down regulation of the receptors for tumor necrosis factor by interleukin 1 and 4 beta-phorbol-12-myristate-13-acetate. (1987) (157)
- Preparations of lymphotoxin induce resistance to their own cytotoxic effect. (1984) (157)
- INTRAMUSCULAR HUMAN INTERFERON-β INJECTIONS IN TREATMENT OF CONDYLOMATA ACUMINATA (1984) (142)
- Cytoplasmic truncation of the p55 tumour necrosis factor (TNF) receptor abolishes signalling, but not induced shedding of the receptor. (1992) (137)
- Receptor-specific signaling for both the alternative and the canonical NF-kappaB activation pathways by NF-kappaB-inducing kinase. (2004) (135)
- A potential mechanism of "cross-talk" between the p55 tumor necrosis factor receptor and Fas/APO1: proteins binding to the death domains of the two receptors also bind to each other (1996) (130)
- CACHECTIN/TUMOUR-NECROSIS-FACTOR PRODUCTION BY CANCER PATIENTS (1985) (130)
- Mutant p53 gain of function: repression of CD95(Fas/APO-1) gene expression by tumor-associated p53 mutants (2003) (130)
- Hijacking of Host Cell IKK Signalosomes by the Transforming Parasite Theileria (2002) (129)
- Shedding kinetics of soluble tumor necrosis factor (TNF) receptors after systemic TNF leaking during isolated limb perfusion. Relevance to the pathophysiology of septic shock. (1998) (129)
- Mutation of a Self-Processing Site in Caspase-8 Compromises Its Apoptotic but Not Its Nonapoptotic Functions in Bacterial Artificial Chromosome-Transgenic Mice1 (2008) (129)
- Caspase-8 promotes cell motility and calpain activity under nonapoptotic conditions. (2006) (129)
- ASSAY OF AN INTERFERON-INDUCED ENZYME IN WHITE BLOOD CELLS AS A DIAGNOSTIC AID IN VIRAL DISEASES (1981) (126)
- Inhibition of Chlamydia trachomatis growth by recombinant tumor necrosis factor (1988) (118)
- Concepts of tissue injury and cell death in inflammation: a historical perspective (2013) (114)
- Apoptosome-Independent Activation of the Lysosomal Cell Death Pathway byCaspase-9 (2006) (113)
- TNF-alpha binds to the N-terminal domain of fibronectin and augments the beta 1-integrin-mediated adhesion of CD4+ T lymphocytes to the glycoprotein. (1994) (110)
- Necroptosis is preceded by nuclear translocation of the signaling proteins that induce it (2015) (106)
- Regulation of B cell homeostasis and activation by the tumor suppressor gene CYLD (2007) (106)
- A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development (2017) (106)
- Soluble tumor necrosis factor receptors and interleukin‐6 levels in patients with severe preeclampsia (1996) (104)
- Selective up-regulation of the 75-kDa tumor necrosis factor (TNF) receptor and its mRNA by TNF and IL-1. (1993) (100)
- Monitoring of interferon therapy by assay of (2'--5') oligo-isoadenylate synthetase in human peripheral white blood cells. (1981) (96)
- Concepts of tissue injury and cell death in inflammation: a historical perspective (2014) (95)
- Structural requirements for inducible shedding of the p55 tumor necrosis factor receptor. (1994) (90)
- Death-inducing functions of ligands of the tumor necrosis factor family: a Sanhedrin verdict. (1998) (86)
- Elevated serum levels of soluble tumour necrosis factor receptors (sTNF‐R) in patients with HIV infection (1992) (86)
- Differential regulation of HLA‐DR mRNAs and cell surface antigens by interferon. (1983) (85)
- Increased expression of tumor necrosis factor-alpha receptors in the brains of patients with AIDS. (1995) (84)
- Apoptosis: Placing death under control (1997) (83)
- Role of caspase‐8 in hepatocyte response to infection and injury in mice (2007) (83)
- Inhibition of tumor necrosis factor alpha (TNFalpha) activity in rat brain is associated with cerebroprotection after closed head injury. (1996) (78)
- Soluble and cell surface receptors for tumor necrosis factor. (1991) (76)
- The interferon-induced enzyme oligo-isoadenylate synthetase: rapid determination of its in vitro products. (1981) (68)
- Caspase-8 deficiency facilitates cellular transformation in vitro (2008) (65)
- Purification of soluble cytokine receptors from normal human urine by ligand-affinity and immunoaffinity chromatography. (1990) (65)
- Reversion of the antichlamydial effect of tumor necrosis factor by tryptophan and antibodies to beta interferon (1989) (64)
- Identification of a cell protein (FIP-3) as a modulator of NF-kappaB activity and as a target of an adenovirus inhibitor of tumor necrosis factor alpha-induced apoptosis. (1999) (62)
- Use of monoclonal antibodies to a human cytotoxin for its isolation and for examining the self-induction of resistance to this protein. (1985) (61)
- Tumor necrosis factor in middle ear effusions. (1988) (61)
- Circulating plasma receptors for tumour necrosis factor in Malawian children with severe falciparum malaria. (1993) (59)
- NF-κB-Inducing Kinase Is Involved in the Activation of the CD28 Responsive Element through Phosphorylation of c-Rel and Regulation of Its Transactivating Activity1 (2006) (59)
- Epstein-Barr virus-transforming protein latent infection membrane protein 1 activates transcription factor NF-kappaB through a pathway that includes the NF-kappaB-inducing kinase and the IkappaB kinases IKKalpha and IKKbeta. (1998) (58)
- TRAF2 plays a dual role in NF‐κB‐dependent gene activation by mediating the TNF‐induced activation of p38 MAPK and IκB kinase pathways (1998) (57)
- Soluble cytokine-receptors are present in normal human urine (1989) (56)
- A protein related to a proteasomal subunit binds to the intracellular domain of the p55 TNF receptor upstream to its ‘death domain’ (1995) (56)
- Phosphorylation of the 26 kDa TNF precursor in monocytic cells and in transfected HeLa cells. (1995) (55)
- Interleukin-6 inhibits the proliferation of B-chronic lymphocytic leukemia cells that is induced by tumor necrosis factor-alpha or -beta (1993) (55)
- Soluble TNF receptor production by activated T lymphocytes: differential effects of acute and chronic exposure to TNF. (1995) (54)
- Transcription-controlled gene therapy against tumor angiogenesis. (2004) (54)
- Inhibition of growth of Chlamydia trachomatis by tumor necrosis factor is accompanied by increased prostaglandin synthesis (1990) (49)
- Increase of vulnerability to lymphotoxin in cells infected by vesicular stomatitis virus and its further augmentation by interferon. (1985) (48)
- The extrinsic cell death pathway and the élan mortel (2008) (47)
- Delivery of Soluble Tumor Necrosis Factor Receptor from In-Situ Forming PLGA Implants: In-Vivo (2000) (47)
- How are the regulators regulated? The search for mechanisms that impose specificity on induction of cell death and NF-κB activation by members of the TNF/NGF receptor family (2002) (47)
- Involvement of interferon in virus-induced lymphopenia. (1983) (46)
- 'Necrosome'-induced inflammation: must cells die for it? (2011) (46)
- Selective decrease in cell surface expression and mRNA level of the 55-kDa tumor necrosis factor receptor during differentiation of HL-60 cells into macrophage-like but not granulocyte-like cells. (1992) (45)
- Cloning and partial characterization of the promoter for the human p55 tumor necrosis factor (TNF) receptor. (1993) (45)
- If the prophet does not come to the mountain: dynamics of signaling complexes in NF-kappaB activation. (2006) (45)
- Interrelated effects of tumor necrosis factor and interleukin 1 on cell viability. (1988) (44)
- Binding of human TNF-α to high-affinity cell surface receptors: Effect of IFN (1986) (42)
- The cybernetics of TNF: Old views and newer ones. (2016) (42)
- Extracellular matrix induces tumour necrosis factor-alpha secretion by an interaction between resting rat CD4+ T cells and macrophages. (1993) (37)
- Exploring cell death mechanisms by analyzing signaling cascades of the TNF/NGF receptor family. (1996) (36)
- Interleukin-6 inhibits the proliferation of B-chronic lymphocytic leukemia cells that is induced by tumor necrosis factor-alpha or -beta. (1993) (36)
- Soluble tumor necrosis factor receptors and soluble interleukin-6 receptor in fetal and maternal sera, coelomic and amniotic fluids in normal and pre-eclamptic pregnancies. (1995) (35)
- Differential regulation of tumour necrosis factor receptors (TNF-R) by IL-4; upregulation of P55 and P75 TNF-R on synovial joint mononuclear cells. (1993) (35)
- Suicide by order: some open questions about the cell-killing activities of the TNF ligand and receptor families. (1996) (34)
- Activation of the NLRP3 inflammasome by proteins that signal for necroptosis. (2014) (33)
- Interferon-lnduced resistance to the killing by NK cells: A preferential effect of IFN-γ (1983) (32)
- Cytotoxins (tumour necrosis factor, lymphotoxin and others): molecular and functional characteristics and interactions with interferons. (1986) (31)
- Dominant negative MORT1/FADD rescues mice from CD95 and TNF‐induced liver failure (2003) (30)
- Variation of (2'-5') oligo A synthetase level in lymphocytes and granulocytes of patients with viral infections and leukemia. (1982) (30)
- Dominance of resistance to the cytocidal effect of tumor necrosis factor in heterokaryons formed by fusion of resistant and sensitive cells. (1988) (29)
- The yeast two-hybrid screening technique and its use in the study of protein-protein interactions in apoptosis. (1998) (29)
- Caspase-8 deficiency in mouse embryos triggers chronic RIPK1-dependent activation of inflammatory genes, independently of RIPK3 (2018) (28)
- Caspase-8 Is Involved in Neovascularization-Promoting Progenitor Cell Functions (2009) (27)
- Long-term protection against the effects of tumour necrosis factor by controlled delivery of the soluble p55 TNF receptor. (1996) (27)
- Up the down staircase (2002) (26)
- Functional discrepancies between tumor necrosis factor and lymphotoxin α explained by trimer stability and distinct receptor interactions (1995) (26)
- An interferon-induced cellular enzyme is incorporated into virions (1980) (25)
- Soluble tumor necrosis factor receptors in maternal plasma and second-trimester amniotic fluid. (1995) (24)
- TRAF2 plays a dual role in NF-kappaB-dependent gene activation by mediating the TNF-induced activation of p38 MAPK and IkappaB kinase pathways. (1998) (24)
- Comparison of (2'-5') oligo-adenylate synthetase and interferon blood-levels in mice early after viral infection. (1982) (23)
- Interferon-induced enzymes: microassays and their applications: purification and assay of (2'-5')-oligoadenylate synthetase and assay of 2'-phosphodiesterase. (1981) (22)
- Programmed Cell Death in Immune Defense: Knowledge and Presumptions. (2018) (22)
- The Tumor Necrosis Factor Family: Family Conventions and Private Idiosyncrasies. (2018) (22)
- Aderka, D. et al. Interleukin-6 inhibits the proliferation of B-chronic lymphocytic leukemia cells that is induced by tumor necrosis factor- or -. Blood 81, 2076−2084 (1993) (21)
- Enhanced release of lymphotoxins by interferon-treated cells. (1983) (21)
- Regulation of susceptibility to natural killer cells' cytotoxicity and regulation of HLA synthesis: differing efficacies of alpha, beta, and gamma interferons. (1982) (21)
- How do cells sense foreign DNA? A new outlook on the function of STING. (2013) (20)
- Proteasome-mediated proteolysis of the interleukin-10 receptor is important for signal downregulation. (2006) (20)
- Induction of soluble tumour necrosis factor receptors during treatment with interleukin-2. (1992) (19)
- Glycosylated recombinant human tumor necrosis factor binding protein-1 reduces mortality, shock, and production of tumor necrosis factor in rabbit Escherichia coli sepsis. (1995) (19)
- Protective effect of natural TNF-binding protein on human TNF-induced toxicity in mice. (1993) (19)
- The gene for the type II (p75) tumor necrosis factor receptor (TNF-RII) is localized on band 1p36.2–p36.3 (1991) (19)
- The TNF cytokine family: one track in a road paved by many. (2013) (18)
- The in vivo significance of necroptosis: lessons from exploration of caspase-8 function. (2014) (17)
- Interferon-induced resistance to the killing by NK cells: a preferential effect of IFN-gamma. (1983) (16)
- Expression of cytokines, growth factors, and their receptors in renal allograft biopsies. (1993) (16)
- MORT1/FADD is involved in liver regeneration. (2005) (16)
- Keeping inflammation at bay (2014) (16)
- Epstein – Barr virus-transforming protein latent infection membrane protein 1 activates transcription factor NFk B through a pathway that includes the NFk B-inducing kinase and the I k B kinases IKK a and IKK b (1998) (15)
- Phosphorylation and dephosphorylation of the RIG-I-like receptors: a safety latch on a fateful pathway. (2013) (14)
- Cloning, sequencing and partial functional characterization of the 5' region of the human p75 tumor necrosis factor receptor-encoding gene (TNF-R). (1994) (14)
- Inhibition by glucocorticosteroid hormones of interferon and prostaglandin E induction by poly(rI). Poly(rC). (1982) (13)
- Soluble tumor necrosis factor receptor expression in patients with metastatic renal cell carcinoma treated with interleukin-2-based immunotherapy. (1993) (13)
- 12th international TNF conference: the good, the bad and the scientists. (2009) (13)
- Pharmacokinetics and tissue distribution of human urinary tumor necrosis factor binding protein in mice. (1992) (12)
- Reduced production of tumor necrosis factor by mononuclear cells in hairy cell leukemia patients and improvement following interferon therapy (1987) (12)
- The HLA proteins and a related protein of 28 kDa are preferentially induced by interferon‐γ in human WISH cells (1983) (12)
- Increased soluble tumor necrosis factor receptor expression and release by human immunodeficiency virus type 1 infection. (1995) (11)
- Cell-autonomous and non-cell-autonomous functions of caspase-8. (2008) (11)
- The gene for the type 1 tumor necrosis factor receptor (TNF-R1) is localized on band 12p13 (1991) (11)
- Hormonal protection of interferon‐treated cells against double‐stranded RNA‐induced cytolysis (1979) (10)
- Self-termination of the terminator (2008) (10)
- Interferon-induced cytotoxicity and (2'-5') oligo(A) synthetase activity in T cells. Differences in responsiveness among T cells from various individuals and among lymphoblastoid T-cell lines. (1984) (10)
- (2'-5') Oligo A synthetase in human polymorphonuclear cells increased activity in interferon treatment and in viral infections. (1984) (10)
- A decade of accumulated knowledge and emerging answers. The 6th international congress on TNF Rhodes, Greece. May 1996. (1996) (10)
- Mechanisms which take part in regulation of the response to tumor necrosis factor. (1989) (10)
- Induction of hyporesponsiveness to an early post‐binding effect of tumor necrosis factor by tumor necrosis factor itself and interleukin 1 (1991) (9)
- Recombinant interferon alpha‐C for advanced hairy cell leukemia. An Israeli multicenter study (1988) (9)
- Soluble Tumor Necrosis Factor Receptors in Health and Disease (1993) (9)
- Anti‐inflammatory functions of the “apoptotic” caspases (2010) (9)
- Quantification of the antiviral effect of interferon by immunoassay of vesicular stomatitis virus proteins. (1983) (8)
- Binding of human TNF-alpha to high-affinity cell surface receptors: effect of IFN. (1986) (8)
- Site-specific ubiquitination of MLKL targets it to endosomes and targets Listeria and Yersinia to the lysosomes (2022) (8)
- Inhibition of tumor necrosis factor-induced cell killing by tryptophan and indole. (1990) (8)
- Cell Surface and Soluble TNF Receptors1 (1992) (7)
- Interactions of Tumor Necrosis Factor, Interferon and Interleukin-1 in Cell Killing (1987) (6)
- Increased Serum Levels of Soluble Receptors for Tumor Necrosis Factor in Cancer (1991) (5)
- The TNF family: only the surface has been scratched. (2014) (5)
- Regulation of the Response to Tumor Necrosis Factor (1988) (5)
- Translation of mRNA for human lymphotoxin in microinjected Xenopus oocytes (1984) (4)
- An immunoenzyme quantitative assay for the antiviral effect of interferons. (1984) (4)
- Involvement of cytotoxins in the immune response to viral infection. (1985) (4)
- Interferon as a possible cause for virus-related lymphocytopenia. (1982) (4)
- Cloning of genomic DNA for tumor necrosis factor and efficient expression in CHO cells. (1988) (4)
- Probing cell death by chemical screening (2005) (4)
- High levels of soluble p55-TNF receptors in seminal and prostatic fluids of normal and infertile men. (1996) (4)
- Soluble cytokine receptors in normal human urine (1990) (4)
- Suppressive effect of TNF-α and IL-1 on alveolar fibroblast proliferation in sarcoidosis (1992) (4)
- Nonapoptotic Roles Caspase-8 Serves Both Apoptotic And (2004) (3)
- A Lymphotoxin-Driven Pathway to Hepatocellular Carcinoma (2011) (3)
- Implications for persistent chlamydial infections of phagocyte-microorganism interplay (1991) (3)
- Presence of Tumor Necrosis Factor and Lymphotoxin in Clinical Interferon Preparations Derived from Leukocytes (1987) (3)
- Diverse Functions of the Tumor Necrosis Factor Receptors: Structure-Activity Considerations (1993) (2)
- Mechanisms controlling the level of receptors for tumor necrosis factor (2005) (2)
- Mechanisms Involved in Regulation of the Response to Tumor Necrosis Factor (1990) (2)
- Screening for proteins that bind to the intracellular domains of the two tumor necrosis factor receptors (TNF-R) revealed effective self-association of the p55 TNF-R “death domain”, which can trigger signaling (1994) (2)
- Anti-inflammatory functions of caspase-8. (2011) (2)
- Artificial Chromosome-Transgenic Mice Not Its Nonapoptotic Functions in Bacterial Caspase-8 Compromises Its Apoptotic but Mutation of a Self-Processing Site in (2008) (2)
- Rapid improvement in a terminal case of hairy cell leukemia treated with a new human recombinant interferon, IFN-alpha-C. (1985) (2)
- INTERFERON-INDUCED PROTEINS: BIOLOGICAL FUNCTIONS AND CLINICAL APPLICATIONS (1982) (2)
- Identification of viral infections in pregnancy by assay of (2'-5')-oligo-isoadenylate synthetase. (1985) (1)
- Roles of TNF and Other Members of the TNF Family in the Regulation of Innate Immunity (2016) (1)
- Increase of Vulnerability to Lymphotoxin in by Vesicular Stomatitis Virus and Its Augmentation by Interferon' Cells Infected Further (1985) (1)
- Correction for Gyrd-Hansen et al., “Apoptosome-Independent Activation of the Lysosomal Cell Death Pathway by Caspase-9” (2017) (1)
- Up the down staircase (2002) (1)
- NF-κB stimulatory pathways linked by a common kinase (1997) (1)
- Tumor necrosis factor receptors of the monocyte derived Langerhans cell phenotype "MoLC". (1995) (1)
- Sensitizing effects and mechanisms of desensitization in regulation of the in vivo response to TNF. (1988) (1)
- Faculty Opinions recommendation of Mixed Lineage Kinase Domain-like Protein MLKL Breaks Down Myelin following Nerve Injury. (2018) (1)
- Tumor necrosis factor-binding protein II, its purification and specific antibodies. (1990) (0)
- Caspase-8 regulates cellular response to pattern recognition receptors and prevents spontaneous triggering of chronic inflammation by their endogenous activators (2009) (0)
- Faculty Opinions recommendation of Caspase-8 can be activated by interchain proteolysis without receptor-triggered dimerization during drug-induced apoptosis. (2005) (0)
- Molecule influencing shedding of tnf receptor, its preparation and its use (1994) (0)
- Cytokine Receptors, Soluble (1998) (0)
- Using Antizytokin-containing pharmaceutical compositions for the treatment of multiple sclerosis (1992) (0)
- 969. Transcription Controlled Gene Therapy Against Tumor Angiogenesis (2004) (0)
- The Role of Tumor Necrosis Factor in Human Granulosa Cells and Early Embryo (1990) (0)
- Faculty Opinions recommendation of Interchain proteolysis, in the absence of a dimerization stimulus, can initiate apoptosis-associated caspase-8 activation. (2005) (0)
- Faculty Opinions recommendation of Telomerase directly regulates NF-κB-dependent transcription. (2012) (0)
- TNF receptors on rat brain oligodendrocytes: Implications for nerve regeneration (1991) (0)
- Putative role of tumor necrosis factor in the loss of dopaminergic neurons in Parkinson's disease (1992) (0)
- PROTEINE IREN (IλB REGULATOR), PRODUCTION ET UTILISATION (2000) (0)
- Materials and Methods Isolation and Ex Vivo Endothelial Differentiation of Human Endothelial Progenitor Cells (2009) (0)
- Modulators function fas receptor and other proteins. (1996) (0)
- Modulators of receptor function of TNF receptor family / NGF. (1999) (0)
- Anticorps diriges contre nik, preparation et emploi (2004) (0)
- The use of pharmaceutical compositions comprising an anticytokine, for the treatment of multiple sclerosis (1992) (0)
- Proceedings of the 12th International TNF Conference, 2009. (2011) (0)
- II binding proteins to Tumor Necrosis Factor, its purification and antibodies thereto (1990) (0)
- Comprar Advances In Tnf Family Research. Proceedings Of The 12th International Tnf Conference, 2009 (Advances In Experimental Medicine And Biology, Vol. 691) | Andrew Kovalenko | 9781441966117 | Springer (2010) (0)
- International Review of Cytology. Supplement 12: Membrane Research-Classic Origins and Current Concepts.G. H. Bourne , J. F. Danielli (1983) (0)
- Faculty Opinions recommendation of Bcl10 activates the NF-kappaB pathway through ubiquitination of NEMO. (2004) (0)
- Increased Serum Levels of Soluble Receptors for Tumor Necrosis Factor in Cancer Patients1 (2006) (0)
- The use of interleukin-6 for the preparation of a pharmaceutical composition for the treatment of lymphocytic leukemia and B-cell lymphoma. (1992) (0)
- Modulating the action of TNF receptor. (1993) (0)
- Modulating the function of the Fas / APO1 receptors. (1995) (0)
- Abstract 1302: Caspase-8-dependent Cleavage Of The E3 Ubiquitin Ligase Cbl-b Regulates Integrin Expression And Adhesion Capacity In Endothelial Progenitor Cells (2007) (0)
- Human natural ifn-bata2/il-6 receptor (1990) (0)
- Caspase-8 deficiency in mouse embryos triggers chronic RIPK1-dependent activation of inflammatory genes, independently of RIPK3 (2018) (0)
- Expression of the binding protein i to tumor necrosis factor TBP-I recombinant. (1990) (0)
- Arzneitmittel for controlled release of soluble receptors (1996) (0)
- Ubiquitination related activity and / or degradation sive and modulators thereof. (2007) (0)
- Promoters for p75 tumor necrosis factor. (1995) (0)
- Purification of TNF binding proteins. (2004) (0)
- A pharmaceutical composition comprising a cytokine (1992) (0)
- Tumor Necrosis Factor Alpha (TNFalpha) (2016) (0)
- Faculty Opinions recommendation of Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3. (2005) (0)
- Modulating the TNF receptor activity (1993) (0)
- Regulation of Its Transactivating Activity through Phosphorylation of c-Rel and Activation of the CD 28 Responsive Element B-Inducing Kinase Is Involved in the κ NF - (2006) (0)
- Derivatives of the NF-kappaB-inducing enzyme, the preparation and use thereof (2003) (0)
- Pharmaceutical compositions containing a Anticytokin (1992) (0)
- Faculty Opinions recommendation of RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis. (2009) (0)
- FADD is involved in liver regeneration (2014) (0)
- Antibodies to TNF binding protein I and their F (ab) fragments. (1990) (0)
- Interferon and lipoid nephrosis. (1988) (0)
- 11 Patent Number : 45 Date of Patent : 5 , 359 , 037 Oct . 25 , 1994 ons ' , in : Interferon 7 (2017) (0)
- Modulators of the TNF receptor-associated factor whose preparation and uses (1997) (0)
- Multimers of the soluble forms of the TNF receptors, to processes for their preparation and pharmaceutical compositions containing them (1992) (0)
- Antibodies to protein which binds to TNF iya its F (ab). (1990) (0)
- Abstract 997: A Novel Apoptosis-Unrelated Role of Caspase-8 in Endothelial Progenitor Cell-Mediated Neovascularization (2006) (0)
- RESISTANCE TO NATURAL-KILLER CELLS' CYTOTOXICITY AND HLA SYNTHESIS: DIFFERING REGULATORY EFFICIENCY OF THE TYPE-I AND IMMUNE INTERFERONS (1982) (0)
- Tumor necrosis factor binding protein II, it's purification and antibodies thereto (1990) (0)
- TNF receptor-modulating effect (1993) (0)
- 69 Structure–Function Analysis In Vivo of Cytokine-Mediated Cell-Death Induction: BAC Transgenic Mice of Caspase-8 Mutants (2007) (0)
- SIGNALING MECHANISMS ACTIVATED BY RECEPTORS OF THE TNF/NGF FAMILY: 296 (1997) (0)
- pharmaceutical compositions for controlled delivery of soluble receptors. (1996) (0)
- Antibodies to nod, their generation, and the use (2004) (0)
- Löslisches extracellular fragment of human metallic IFN-beta 2 / IL-6 receptor, its preparation and this fragment containing pharmaceutical mixture (1990) (0)
- SS8-1 The ‘apoptotic’ caspases as regulators of inflammation: new lessons from the study of caspase-8 function (2010) (0)
- A method of determining interferon and reagent for performing the method (1980) (0)
- anti-NIK antibodies and their uses (2004) (0)
- 845 High mortality and delayed onset of proliferation after partial hepatectomy in transgenic mice expressing dominant negative MORT1/FADD in hepatocytes (2003) (0)
- Use of a caspase-8 inhibitors to modulating hematopoiesis (2006) (0)
- Modulations of Fas / Apo1-receptors function (1995) (0)
- Levels of soluble receptors for tumor necrosis factor type I and type II in paired synovial fluids of arthritis patients (2004) (0)
- 47 Regulation of Inflammation and Cell-Death Trough Interactions of RHIM-domain Protein Kinases With Caspase-8 (2012) (0)
- Expression of recombinant tumor necrosis factor binding protein I (TBP-I) (1990) (0)
- Faculty of 1000 evaluation for NF-κB inducing kinase is a therapeutic target for systemic lupus erythematosus. (2018) (0)
- Compositions for modulating the effects of TNF and IL-1. (1987) (0)
- Faculty Opinions recommendation of Phosphorylation of NLRC4 is critical for inflammasome activation. (2012) (0)
- Faculty Opinions recommendation of IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis. (2007) (0)
- The role of mort1/FADD in apoptosis and liver regeneration (2003) (0)
- Tumor necrosis factor suppressive proteins and their purification (1988) (0)
- Apoptotic cell death in disease—Current understanding of the NCCD 2023 (2023) (0)
- Faculty Opinions recommendation of Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation. (2009) (0)
- Pharmaceutical compositions for the controlled release of oplöselige receptors (1996) (0)
- THE NF‐KB SIGNALING CASCADE AND HUMAN PATHOLOGIES: 179 (2004) (0)
- ELEVATED LEVELS OF TUMOR NECROSIS FACTOR (TNF) IN ADOLESCENTS ON HEMODIALYSIS (HD) (1987) (0)
- A monoclonal antibody against a cytotoxin, the same producing hybridomas and methods for preparing the purified cytotoxin. (1985) (0)
- Faculty Opinions recommendation of Noncanonical inflammasome activation by intracellular LPS independent of TLR4. (2013) (0)
- Pharmaceutical preparations containing a cytokine. (1992) (0)
- Keeping inflammation at bay Cells dying by apoptosis can trigger an anti-inflammatory gene response in other cells by releasing a compound called adenosine monophosphate. (2014) (0)
- Faculty Opinions recommendation of Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway. (2001) (0)
- Regulation of Cell-Death and Immune Defense by receptors of the TNF/NGF family (2006) (0)
- FAS / APO1 receptor activity modulators (1997) (0)
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