David A. Wheeler
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Computer Science
David A. Wheeler's Degrees
- PhD Computer Science Stanford University
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(Suggest an Edit or Addition)David A. Wheeler's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Integrated Genomic Analyses of Ovarian Carcinoma (2011) (6411)
- Comprehensive molecular characterization of human colon and rectal cancer (2012) (6141)
- Comprehensive genomic characterization defines human glioblastoma genes and core pathways (2008) (5775)
- Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project (2007) (5196)
- A second generation human haplotype map of over 3.1 million SNPs (2007) (4567)
- Comprehensive genomic characterization of squamous cell lung cancers (2012) (2998)
- Comprehensive genomic characterization of head and neck squamous cell carcinomas (2015) (2860)
- The Immune Landscape of Cancer (2018) (2766)
- Integrating common and rare genetic variation in diverse human populations (2010) (2731)
- Somatic mutations affect key pathways in lung adenocarcinoma (2008) (2640)
- Genomic analyses identify molecular subtypes of pancreatic cancer (2016) (2343)
- Genome sequence of the Brown Norway rat yields insights into mammalian evolution (2004) (2053)
- Integrated Genomic Characterization of Papillary Thyroid Carcinoma (2014) (2007)
- The complete genome of an individual by massively parallel DNA sequencing (2008) (1874)
- International network of cancer genome projects (2010) (1839)
- Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes (2012) (1752)
- Comprehensive molecular characterization of clear cell renal cell carcinoma (2013) (1724)
- The repertoire of mutational signatures in human cancer (2018) (1656)
- Exome Sequencing of Head and Neck Squamous Cell Carcinoma Reveals Inactivating Mutations in NOTCH1 (2011) (1652)
- Oncogenic Signaling Pathways in The Cancer Genome Atlas (2018) (1646)
- Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma (2017) (1514)
- Comprehensive Characterization of Cancer Driver Genes and Mutations (2018) (1360)
- Comprehensive Characterization of Cancer Driver Genes and Mutations (2018) (1360)
- Insights into social insects from the genome of the honeybee Apis mellifera (2006) (1356)
- Evolutionary and Biomedical Insights from the Rhesus Macaque Genome (2007) (1309)
- Characterizing the cancer genome in lung adenocarcinoma (2007) (1122)
- Integrated Genomic Characterization of Pancreatic Ductal Adenocarcinoma. (2017) (1092)
- The DNA sequence of the human X chromosome (2005) (1072)
- Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma. (2016) (931)
- Genome-Wide Survey of SNP Variation Uncovers the Genetic Structure of Cattle Breeds (2009) (778)
- Whole-genome sequencing in a patient with Charcot-Marie-Tooth neuropathy. (2010) (777)
- Direct selection of human genomic loci by microarray hybridization (2007) (681)
- The somatic genomic landscape of chromophobe renal cell carcinoma. (2014) (646)
- Landscape of Somatic Retrotransposition in Human Cancers (2012) (638)
- Whole-genome landscape of pancreatic neuroendocrine tumours (2017) (616)
- Trans-ancestry mutational landscape of hepatocellular carcinoma genomes (2014) (600)
- Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas (2018) (600)
- Comparative genome sequencing of Drosophila pseudoobscura: chromosomal, gene, and cis-element evolution. (2005) (548)
- Pathogenic Germline Variants in 10,389 Adult Cancers (2018) (501)
- Pathogenic Germline Variants in 10,389 Adult Cancers (2018) (501)
- The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma (2018) (480)
- Scalable Open Science Approach for Mutation Calling of Tumor Exomes Using Multiple Genomic Pipelines. (2018) (478)
- Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients (2018) (471)
- Integrative genomic characterization of oral squamous cell carcinoma identifies frequent somatic drivers. (2013) (467)
- Mutational Landscape of Aggressive Cutaneous Squamous Cell Carcinoma (2014) (450)
- Mutations in smooth muscle alpha-actin (ACTA2) cause coronary artery disease, stroke, and Moyamoya disease, along with thoracic aortic disease. (2009) (436)
- Patterns of somatic structural variation in human cancer genomes (2020) (377)
- Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles (2017) (361)
- Dynamic analyses of alternative polyadenylation from RNA-seq reveal a 3′-UTR landscape across seven tumour types (2014) (355)
- Diagnostic Yield of Clinical Tumor and Germline Whole-Exome Sequencing for Children With Solid Tumors. (2016) (351)
- Comprehensive Characterization of Cancer Driver Genes and Mutations (2018) (340)
- TTC21B contributes both causal and modifying alleles across the ciliopathy spectrum (2011) (337)
- Mutually exclusive recurrent somatic mutations in MAP2K1 and BRAF support a central role for ERK activation in LCH pathogenesis. (2014) (330)
- Genetic Mechanisms of Immune Evasion in Colorectal Cancer. (2018) (305)
- Orphan Nuclear Receptor LRH-1 Is Required To Maintain Oct4 Expression at the Epiblast Stage of Embryonic Development (2005) (299)
- Mutational Strand Asymmetries in Cancer Genomes Reveal Mechanisms of DNA Damage and Repair (2016) (299)
- Characterization of HPV and host genome interactions in primary head and neck cancers (2014) (296)
- Exome Sequencing of Ion Channel Genes Reveals Complex Profiles Confounding Personal Risk Assessment in Epilepsy (2011) (296)
- Comprehensive Pan-Genomic Characterization of Adrenocortical Carcinoma. (2016) (295)
- Multilevel Genomics-Based Taxonomy of Renal Cell Carcinoma. (2016) (284)
- Activation of Multiple Proto-oncogenic Tyrosine Kinases in Breast Cancer via Loss of the PTPN12 Phosphatase (2011) (277)
- Rise and fall of subclones from diagnosis to relapse in pediatric B-acute lymphoblastic leukaemia (2015) (276)
- A common allele in RPGRIP1L is a modifier of retinal degeneration in ciliopathies (2009) (275)
- Integrated Analysis of TP53 Gene and Pathway Alterations in The Cancer Genome Atlas. (2019) (273)
- Integrated Molecular Characterization of Testicular Germ Cell Tumors (2018) (261)
- A recurrent germline PAX5 mutation confers susceptibility to pre-B cell acute lymphoblastic leukemia (2013) (253)
- A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing (2015) (250)
- Genomic profiling of Sézary syndrome identifies alterations of key T cell signaling and differentiation genes (2015) (250)
- Deep resequencing reveals excess rare recent variants consistent with explosive population growth (2010) (244)
- Comprehensive Pan-Genomic Characterization of Adrenocortical Carcinoma. (2016) (241)
- Exonuclease mutations in DNA polymerase epsilon reveal replication strand specific mutation patterns and human origins of replication (2014) (237)
- Genomic analysis of the nuclear receptor family: new insights into structure, regulation, and evolution from the rat genome. (2004) (236)
- Perspective on Oncogenic Processes at the End of the Beginning of Cancer Genomics (2018) (234)
- Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genome. (2007) (221)
- Analyses of non-coding somatic drivers in 2,658 cancer whole genomes (2020) (220)
- Copy number variation detection in whole-genome sequencing data using the Bayesian information criterion (2011) (219)
- Genome-wide detection and characterization of positive selection in human populations (2007) (217)
- Prediction of missense mutation functionality depends on both the algorithm and sequence alignment employed (2011) (213)
- Recurrent DGCR8, DROSHA, and SIX homeodomain mutations in favorable histology Wilms tumors. (2015) (210)
- A Children's Oncology Group and TARGET Initiative Exploring the Genetic Landscape of Wilms Tumor (2017) (201)
- Orphan Nuclear Receptor GCNF Is Required for the Repression of Pluripotency Genes during Retinoic Acid-Induced Embryonic Stem Cell Differentiation (2005) (199)
- Retromer terminates the generation of cAMP by internalized PTH-receptors (2011) (198)
- Comprehensive molecular characterization of mitochondrial genomes in human cancers (2017) (197)
- Proteogenomic Characterization of Endometrial Carcinoma (2020) (194)
- Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context (2018) (188)
- A SNP discovery method to assess variant allele probability from next-generation resequencing data. (2010) (180)
- Combined sequence-based and genetic mapping analysis of complex traits in outbred rats (2013) (176)
- Demographic Histories and Patterns of Linkage Disequilibrium in Chinese and Indian Rhesus Macaques (2007) (175)
- MuSE: accounting for tumor heterogeneity using a sample-specific error model improves sensitivity and specificity in mutation calling from sequencing data (2016) (168)
- Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes (2020) (166)
- Tumor necrosis factor‐α‐induced neutral sphingomyelinase‐2 modulates synaptic plasticity by controlling the membrane insertion of NMDA receptors (2009) (164)
- Novel somatic and germline mutations in intracranial germ cell tumours (2014) (160)
- Comprehensive Genomic Characterization of Upper Tract Urothelial Carcinoma. (2017) (155)
- ARTD1/PARP1 negatively regulates glycolysis by inhibiting hexokinase 1 independent of NAD+ depletion. (2014) (152)
- Assessing structural variation in a personal genome—towards a human reference diploid genome (2015) (143)
- Genomic analysis of hepatoblastoma identifies distinct molecular and prognostic subgroups (2017) (143)
- A defect of sphingolipid metabolism modifies the properties of normal appearing white matter in multiple sclerosis (2008) (141)
- SNPdetector: A Software Tool for Sensitive and Accurate SNP Detection (2005) (136)
- From human genome to cancer genome: The first decade (2013) (134)
- ApoE4 disrupts sterol and sphingolipid metabolism in Alzheimer's but not normal brain (2009) (124)
- Squamous Cell Carcinoma of the Oral Tongue in Young Non-Smokers Is Genomically Similar to Tumors in Older Smokers (2014) (123)
- Genomic Profiling of Pediatric Acute Myeloid Leukemia Reveals a Changing Mutational Landscape from Disease Diagnosis to Relapse. (2016) (121)
- Recurrent internal tandem duplications of BCOR in clear cell sarcoma of the kidney (2015) (113)
- BCOR-CCNB3 Fusions Are Frequent in Undifferentiated Sarcomas of Male Children (2014) (111)
- Integrated Analyses of microRNAs Demonstrate Their Widespread Influence on Gene Expression in High-Grade Serous Ovarian Carcinoma (2012) (110)
- Identification of a pan-cancer oncogenic microRNA superfamily anchored by a central core seed motif (2013) (110)
- Cross-species identification of genomic drivers of squamous cell carcinoma development across preneoplastic intermediates (2016) (105)
- Alternative genetic mechanisms of BRAF activation in Langerhans cell histiocytosis. (2016) (104)
- Erratum : The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma (Cell Reports (2018) 23(1) (313–326.e5) (S2211124718304364) (10.1016/j.celrep.2018.03.075)) (2018) (103)
- Analysis of Genomes and Transcriptomes of Hepatocellular Carcinomas Identifies Mutations and Gene Expression Changes in the Transforming Growth Factor-β Pathway. (2018) (99)
- Ampullary Cancers Harbor ELF3 Tumor Suppressor Gene Mutations and Exhibit Frequent WNT Dysregulation. (2016) (96)
- Integrative pathway enrichment analysis of multivariate omics data (2018) (96)
- Calcium/Calmodulin-Dependent Protein Kinase (CaMK) IV Mediates Nucleocytoplasmic Shuttling and Release of HMGB1 during Lipopolysaccharide Stimulation of Macrophages1 (2008) (93)
- Novel estrogen response elements identified by genetic selection in yeast are differentially responsive to estrogens and antiestrogens in mammalian cells. (1994) (92)
- Erratum: Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles (Cell Reports (2017) 18(11) (2780–2794) (S2211124717302140) (10.1016/j.celrep.2017.02.033)) (2017) (88)
- Amphetamine Modulates Excitatory Neurotransmission through Endocytosis of the Glutamate Transporter EAAT3 in Dopamine Neurons (2014) (87)
- Disruptive TP53 Mutation Is Associated with Aggressive Disease Characteristics in an Orthotopic Murine Model of Oral Tongue Cancer (2011) (87)
- The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma. (2018) (86)
- Parathyroid Hormone Receptor Directly Interacts with Dishevelled to Regulate β-Catenin Signaling and Osteoclastogenesis* (2010) (84)
- Molecular profiling predicts meningioma recurrence and reveals loss of DREAM complex repression in aggressive tumors (2019) (83)
- NHERF-1 and the Cytoskeleton Regulate the Traffic and Membrane Dynamics of G Protein-coupled Receptors* (2007) (82)
- Genomic Profiling of Childhood Tumor Patient-Derived Xenograft Models to Enable Rational Clinical Trial Design (2019) (80)
- Cancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis (2020) (80)
- Chemistry-First Approach for Nomination of Personalized Treatment in Lung Cancer (2018) (73)
- MLH1‐silenced and non‐silenced subgroups of hypermutated colorectal carcinomas have distinct mutational landscapes (2013) (69)
- Initial testing (stage 1) of the PARP inhibitor BMN 673 by the pediatric preclinical testing program: PALB2 mutation predicts exceptional in vivo response to BMN 673 (2015) (69)
- Genomic Alterations of Adamantinomatous and Papillary Craniopharyngioma (2017) (67)
- Significance of TP53 Mutation in Wilms Tumors with Diffuse Anaplasia: A Report from the Children's Oncology Group (2016) (65)
- Effects of TP53 mutational status on gene expression patterns across 10 human cancer types (2014) (64)
- SMARCA4-inactivating mutations increase sensitivity to Aurora kinase A inhibitor VX-680 in non-small cell lung cancers (2017) (63)
- Pathway and network analysis of more than 2500 whole cancer genomes (2018) (62)
- Amphetamine activates Rho GTPase signaling to mediate dopamine transporter internalization and acute behavioral effects of amphetamine (2015) (61)
- Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles. (2017) (61)
- The DNA sequence, annotation and analysis of human chromosome 3 (2006) (60)
- Novel MicroRNA Candidates and miRNA-mRNA Pairs in Embryonic Stem (ES) Cells (2008) (57)
- Destabilized SMC5/6 complex leads to chromosome breakage syndrome with severe lung disease (2016) (56)
- SubcloneSeeker: a computational framework for reconstructing tumor clone structure for cancer variant interpretation and prioritization (2014) (55)
- Erratum: Comprehensive Pan-Genomic Characterization of Adrenocortical Carcinoma (Cancer Cell (2016) 29(5) (723–736) (S153561081630160X) (10.1016/j.ccell.2016.04.002)) (2016) (54)
- Identification of TP53 as an acute lymphocytic leukemia susceptibility gene through exome sequencing (2013) (53)
- MLLT1 YEATS domain mutations in clinically distinctive Favourable Histology Wilms tumours (2015) (53)
- The Breast Cancer Gene Database: a collaborative information resource (1999) (51)
- The finished DNA sequence of human chromosome 12 (2006) (49)
- Direct interaction between NHERF1 and Frizzled regulates β-catenin signaling (2010) (47)
- Genomes for Kids: The Scope of Pathogenic Mutations in Pediatric Cancer Revealed by Comprehensive DNA and RNA Sequencing (2021) (46)
- Discovery and characterization of coding and non-coding driver mutations in more than 2,500 whole cancer genomes (2017) (46)
- Mixed-phenotype acute leukemia (MPAL) exhibits frequent mutations in DNMT3A and activated signaling genes. (2016) (45)
- Regulation of parathyroid hormone type 1 receptor dynamics, traffic, and signaling by the Na+/H+ exchanger regulatory factor-1 in rat osteosarcoma ROS 17/2.8 cells. (2008) (43)
- Mammalian hexokinase 1: evolutionary conservation and structure to function analysis. (1991) (43)
- Genomic scanning for expressed sequences in Xp21 identifies the glycerol kinase gene (1993) (42)
- Sex differences in oncogenic mutational processes (2019) (41)
- Zebrafish dax1 is required for development of the interrenal organ, the adrenal cortex equivalent. (2006) (40)
- Genomic sequencing for cancer diagnosis and therapy. (2014) (39)
- Molecular Features of Cancers Exhibiting Exceptional Responses to Treatment. (2020) (38)
- Landscape of somatic single nucleotide variants and indels in colorectal cancer and impact on survival (2020) (38)
- Genome-Wide Analysis of Binding Sites and Direct Target Genes of the Orphan Nuclear Receptor NR2F1/COUP-TFI (2010) (38)
- Telomere Maintenance Mechanisms Define Clinical Outcome in High-Risk Neuroblastoma (2020) (37)
- Integrated Proteogenomic Characterization of Clear Cell Renal Cell Carcinoma (2020) (36)
- GERM CELL TUMOURS (2014) (35)
- Characterization of single-nucleotide variation in Indian-origin rhesus macaques (Macaca mulatta) (2011) (34)
- Differential Regulation of Two Isoforms of the Glial Glutamate Transporter EAAT2 by DLG1 and CaMKII (2015) (33)
- Erratum: Integrated Analysis of TP53 Gene and Pathway Alterations in The Cancer Genome Atlas (Cell Reports (2019) 28(5) (1370–1384.e5), (S221112471930885X), (10.1016/j.celrep.2019.07.001)) (2019) (32)
- Combined burden and functional impact tests for cancer driver discovery using DriverPower (2020) (31)
- Reconstructing evolutionary trajectories of mutation signature activities in cancer using TrackSig (2020) (30)
- PEX7 and EBP50 target iNOS to the peroxisome in hepatocytes. (2013) (29)
- An enhanced genetic model of colorectal cancer progression history (2019) (28)
- Inferring structural variant cancer cell fraction (2020) (27)
- Genomes and phenomes of a population of outbred rats and its progenitors (2014) (25)
- Gene expression profiling and immune cell-type deconvolution highlight robust disease progression and survival markers in multiple cohorts of CTCL patients (2018) (24)
- Role of phospholipase D in parathyroid hormone type 1 receptor signaling and trafficking. (2009) (24)
- Focused Analysis of Exome Sequencing Data for Rare Germline Mutations in Familial and Sporadic Lung Cancer (2016) (23)
- Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples (2020) (22)
- Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples (2020) (22)
- MuSE: accounting for tumor heterogeneity using a sample-specific error model improves sensitivity and specificity in mutation calling from sequencing data (2016) (21)
- Non-malignant respiratory epithelial cells preferentially proliferate from resected non-small cell lung cancer specimens cultured under conditionally reprogrammed conditions (2016) (20)
- Activating MAPK1 (ERK2) mutation in an aggressive case of disseminated juvenile xanthogranuloma (2017) (20)
- Integrated Analysis of TP53 Gene and Pathway Alterations in The Cancer Genome Atlas. (2019) (20)
- DNA methylation patterns identify subgroups of pancreatic neuroendocrine tumors with clinical association (2021) (20)
- Integrated tumor and germline whole-exome sequencing identifies mutations in MAPK and PI3K pathway genes in an adolescent with rosette-forming glioneuronal tumor of the fourth ventricle (2016) (20)
- Overview of the Development of Personalized Genomic Medicine and Surgery (2011) (19)
- Whole-exome sequencing of polycythemia vera revealed novel driver genes and somatic mutation shared by T cells and granulocytes (2014) (19)
- Coexistence of gain-of-function JAK2 germ line mutations with JAK2V617F in polycythemia vera. (2016) (19)
- ITD assembler: an algorithm for internal tandem duplication discovery from short-read sequencing data (2016) (18)
- Deep resequencing and association analysis of schizophrenia candidate genes (2013) (18)
- The relationship of JAK2V617F and acquired UPD at chromosome 9p in polycythemia vera (2014) (18)
- An open access pilot freely sharing cancer genomic data from participants in Texas (2016) (17)
- Rare Variants in Known Susceptibility Loci and Their Contribution to Risk of Lung Cancer (2018) (16)
- High incidence of IDH mutations in acute myeloid leukaemia with cuplike nuclei (2011) (16)
- Framework for microRNA variant annotation and prioritization using human population and disease datasets (2018) (15)
- Accumulation of Molecular Aberrations Distinctive to Hepatocellular Carcinoma Progression (2020) (14)
- Common and rare variants of DAOA in bipolar disorder (2009) (14)
- Consortium, G.P A map of human genome variation from population-scale sequencing. Nature 467, 1061-1073 (2010) (13)
- The PDZ Protein Na+/H+ Exchanger Regulatory Factor-1 (NHERF1) Regulates Planar Cell Polarity and Motile Cilia Organization (2016) (13)
- Identification of genetic susceptibility to childhood cancer through analysis of genes in parallel. (2011) (13)
- Erratum: Orphan nuclear receptor GCNF is required for the repression of pluripotency genes during retinoic acid-induced embryonic stem cell differentiation (Molecular and Cellular Biology (2005) 25, 19 (8507-8519)) (2005) (13)
- The Exceptional Responders Initiative: Feasibility of A National Cancer Institute Pilot Study. (2020) (12)
- Targeting iCre expression to murine progesterone receptor cell‐lineages using bacterial artificial chromosome transgenesis (2006) (11)
- Clonal Dynamics In Vivo of Virus Integration Sites of T Cells Expressing a Safety Switch. (2016) (11)
- Acquired uniparental disomy of chromosome 9p in hematologic malignancies. (2016) (10)
- A haplotype map of the human genome The International HapMap Consortium (2005) (10)
- Building a Comprehensive Genomic Program for Hepatocellular Carcinoma (2011) (10)
- A comprehensive multicenter comparison of whole genome sequencing pipelines using a uniform tumor-normal sample pair (2014) (10)
- Identification of Novel Somatic Mutations, Regions of Recurrent Loss of Heterozygosity (LOH) and Significant Clonal Evolution From Diagnosis to Relapse in Childhood AML Determined by Exome Capture Sequencing – an NCI/COG Target AML Study (2012) (9)
- National Cancer Institute Biospecimen Evidence-Based Practices: Harmonizing Procedures for Nucleic Acid Extraction from Formalin-Fixed, Paraffin-Embedded Tissue. (2018) (9)
- Renal cell carcinoma harboring somatic TSC2 mutations in a child with methylmalonic acidemia (2017) (8)
- SVachra: a tool to identify genomic structural variation in mate pair sequencing data containing inward and outward facing reads (2017) (8)
- Genomes and phenomes of a population of outbred rats and its progenitors (2014) (8)
- RNAseqCNV: analysis of large-scale copy number variations from RNA-seq data (2022) (7)
- The Cancer Genome Workbench: Identifying and Visualizing Complex Genetic Alterations in Tumors (2010) (7)
- A Comprehensive Assessment of Somatic Mutation Calling in Cancer Genomes (2014) (7)
- Comparison Of Mutational Profiles Of Diagnosis and Relapsed Pediatric B-Acute Lymphoblastic Leukemia: A Report From The COG ALL Target Project (2013) (6)
- Corrigendum: Whole-genome landscape of pancreatic neuroendocrine tumours (2017) (6)
- Novel anaplastic thyroid cancer PDXs and cell lines: Expanding preclinical models of genetic diversity. (2021) (6)
- Resequencing of IRS2 reveals rare variants for obesity but not fasting glucose homeostasis in Hispanic children. (2011) (6)
- Erratum to Recurrent DGCR8, DROSHA, and SIX Homeodomain Mutations in Favorable Histology Wilms Tumors [Cancer Cell., 27, 286-297 (2015)] DOI: 10.1016/j.ccell.2015.02.008 (2015) (5)
- The Proximal Airway Is a Reservoir for Adaptive Immunologic Memory in Idiopathic Subglottic Stenosis (2020) (5)
- Mutation of phenylalanine-34 of parathyroid hormone disrupts NHERF1 regulation of PTH type I receptor signaling (2006) (5)
- Case series of patients with acute myeloid leukemia receiving hypomethylation therapy and retrospectively found to have IDH1 or IDH2 mutations (2014) (5)
- Identifying Gene Disruptions in Novel Balanced de novo Constitutional Translocations in Childhood Cancer Patients by Whole Genome Sequencing (2014) (5)
- A High-Throughput Approach to Identify Effective Systemic Agents for the Treatment of Anaplastic Thyroid Carcinoma. (2021) (5)
- Genome Wide Promoter Methylation Patterns Predict AML Subtype Outcomes and Identify Novel Pathways Characterizing Diagnostic and Relapsed Disease in Children (2012) (4)
- SV-STAT accurately detects structural variation via alignment to reference-based assemblies (2016) (4)
- Glutathione peroxidase 2 is a metabolic driver of the tumor immune microenvironment and immune checkpoint inhibitor response (2022) (4)
- Clinically Significant Mutations, Deletions and Translocations Involving ETV6 Identified by Whole Genome and Whole Exome Sequencing; Report From NCI/COG Target AML Initiative (2012) (4)
- A Primer on a Hepatocellular Carcinoma Bioresource Bank Using the Cancer Genome Atlas Guidelines: Practical Issues and Pitfalls (2011) (3)
- Abstract 926: Multi-Center Mutation Calling in Multiple Cancers: The MC3 Project (2018) (3)
- Abstract LB-93: Demonstration of significant clonal evolution from diagnosis to relapse in childhood AML determined by exome capture sequencing: an NCI/COG TARGET AML study (2012) (3)
- Comprehensive genomic characterization of upper tract urothelial carcinoma (UTUC). (2017) (3)
- Identification of novel fusion transcripts in meningioma (2020) (2)
- Genomic Characterization of Sinonasal Undifferentiated Carcinoma (2014) (2)
- Author Correction: The repertoire of mutational signatures in human cancer (2020) (2)
- Pharmacogenetic characterization of naturally occurring germline NT5C1A variants to chemotherapeutic nucleoside analogs (2016) (2)
- Abstract 3745: Comprehensive integrative characterization of hepatocellular carcinoma: The TCGA HCC project (2015) (2)
- Corrigendum: TTC21B contributes both causal and modifying alleles across the ciliopathy spectrum (2011) (2)
- Abstract IA16: Clinical genomics for children with solid tumors: Current realities and future opportunities (2016) (2)
- ITD assembler: an algorithm for internal tandem duplication discovery from short-read sequencing data (2015) (2)
- Analysis of somatic retrotransposition in human cancers (2012) (2)
- Abstract IA16: Evaluating the implementation and utility of clinical tumor exome sequencing in the pediatric oncology clinic: Early results of the BASIC3 study (2014) (2)
- Whole Genome Sequencing of Four CD34+-Derived iPSC Polycythemia Vera Clones From a Single Female (2012) (2)
- Mini-extracorporeal Circulation and Off-pump Techniques Associated with Less Inflammatory Gene Expression as Compared to On-Pump in the 24-hour Postoperative Window Following Coronary Artery Bypass Grafting (2015) (2)
- Abstract A33: Discovery of chimeric transcripts involving APC and TERT in pediatric HCC by RNA sequencing (2016) (2)
- What’s in an exome? Diversity of diagnostic and incidental findings revealed by clinical tumor and germline sequencing of 100 children with solid tumors. (2014) (2)
- Mixed Phenotype Acute Leukemia (MPAL) Has a High Frequency of Mutations in Epigenetic Regulatory Genes: Results from Whole Exome Sequencing (2014) (2)
- Detection and characterization of replication origins defined by DNA polymerase epsilon (2021) (1)
- Abstract 5506: NOTCH1 activation in head and neck squamous cell carcinoma leads to growth inhibition, changes in gene expression associated with early differentiation, and acquisition of stem cell-like properties (2018) (1)
- OMICS AND PROGNSTIC MARKERS (2013) (1)
- COMPREHENSIVE GENOMIC CHARACTERIZATION OF UPPER TRACT UROTHELIAL CARCINOMA (UTUC): MP71‐01 (2017) (1)
- Comparison of human VDAC1 with streptococcal streptokinase and bovine bactericidal permeability increasing protein: role of structural information in identifying functionally significant domains. (1995) (1)
- An enhanced genetic model of colorectal cancer progression history (2019) (1)
- Abstract 124: Molecular pathogenesis of an advanced cutaneous T-cell lymphoma (2016) (1)
- SubcloneSeeker: a computational framework for reconstructing tumor clone structure for cancer variant interpretation and prioritization (2014) (1)
- Implementation and evaluation of clinical exome sequencing in childhood cancer care: The BASIC3 study. (2013) (1)
- Abstract PS5-01: Biomarkers of resistance to palbociclib in ER+ primary breast cancer in the PALLET trial (2021) (1)
- Abstract 11: Evaluating cancer susceptibility mutations and incidental findings from whole exome sequencing of sequentially diagnosed pediatric solid and brain tumor patients: Early results of the BASIC3 study (2014) (1)
- Abstract 1114: Polymerase epsilon (POLE) mutations and mutator phenotypes in colorectal and endometrial tumors. (2013) (1)
- Abstract 5221: Linking the molecular profile of colorectal tumors to germline genetic and environmental risk factors (2016) (1)
- Abstract 2976: Comprehensive Pan-Genomic characterization of adrenocortical carcinoma (2015) (1)
- DNA methylation patterns identify subgroups of pancreatic neuroendocrine tumors with clinical association (2021) (1)
- Author Correction: Pathway and network analysis of more than 2500 whole cancer genomes (2020) (1)
- Whole Exome Sequencing of Polycythemia Vera Reveals Novel Recurrent Somatic and Germline Variation (2012) (1)
- QS383. Calcium/Calmodulin-Dependent Protein Kinase IV Mediates Nucleocytoplasmic Shuttling and Release of HMGB1 During LPS Stimulation of Macrophages (2008) (1)
- Consensus subtypes of hepatocellular carcinoma associated with clinical outcomes and genomic phenotypes (2022) (1)
- Author Correction: Pan-cancer analysis of whole genomes (2023) (1)
- Author Correction: Combined burden and functional impact tests for cancer driver discovery using DriverPower (2020) (1)
- Author Correction: Reconstructing evolutionary trajectories of mutation signature activities in cancer using TrackSig (2020) (1)
- Stimulation of Macrophages HMGB 1 during Lipopolysaccharide Nucleocytoplasmic Shuttling and Release of Kinase ( CaMK ) IV Mediates Calcium / Calmodulin-Dependent Protein (2008) (1)
- Author Correction: Integrative pathway enrichment analysis of multivariate omics data (2020) (1)
- 231 Patterns of Tumor Evolution in High-grade Ovarian Adenocarcinoma (2012) (0)
- Abstract 2370: Comparative evaluation of somatic mutations calls on single nucleotide variants and structural variants using breast cancer cell lines (2014) (0)
- Abstract PR06: The ampullary adenocarcinoma, its molecular characterization and differentiation from the pancreatic ductal adenocarcinoma, duodenal adenocarcinoma, and cholangiocarcinoma (2015) (0)
- Cell Reports Resource The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma (2018) (0)
- Author Correction: Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples (2020) (0)
- Abstract 3814: Exome sequencing for identification of causative genes for mosaic variegated aneuploidy. (2013) (0)
- Abstract 4592: Exome sequencing of hepatoblastoma reveals recurrent mutations inNFE2L2. (2013) (0)
- Molecular Characterization Of Polycythemia Vera Based On The Relationship Of JAK2V617F and 9pUPD (2013) (0)
- Reply (2007) (0)
- Abstract 642: Genomes for Kids: Comprehensive DNA and RNA sequencing defining the scope of actionable mutations in pediatric cancer (2021) (0)
- Genomic landscape of 261 childhood cancer patient-derived xenograft models (2019) (0)
- Abstract IA21: Developing a new functional classification of lung cancer based on tumor acquired vulnerabilities. (2014) (0)
- Clonal Evolution of the HER2 L755S Mutation Leads to Acquired HER‐targeted Therapy Resistance That Can Be Reversed by the Irreversible HER1/2 Inhibitor Afatinib (2015) (0)
- 7th International Symposium on NeuroVirology (2011) (0)
- Abstract 3301: Uncovering novel radiation sensitivity syndromes through exome sequencing (2015) (0)
- Abstract 4267: Integrated genomic analysis of hepatoblastoma identifies distinct molecular and prognostic subgroups (2015) (0)
- Abstract 5229: Candidate gene analysis of exome sequencing data in smokers susceptible and resistant to chronic obstructive pulmonary disease (2016) (0)
- Human Cancer Biology Disruptive TP 53 Mutation Is Associated with Aggressive Disease Characteristics in an Orthotopic Murine Model of Oral Tongue Cancer (2011) (0)
- Integrated Genomic Analysis of Down Syndrome Acute Lymphoblastic Leukemia Reveals Recurrent Cancer Gene Alterations and Evidence of Frequent Subclonal Driver Events (2016) (0)
- Abstract A8: Functional analysis of genomic variants identified through whole exome sequencing of pediatric lymphocytic leukemia kindreds (2014) (0)
- GE-06IDENTIFICATION OF TARGETABLE MUTATIONS IN RARE PEDIATRIC BRAIN TUMORS BY CLINICAL WHOLE EXOME SEQUENCING (2015) (0)
- Integrated comprehensive genomic characterization of upper tract urothelial carcinoma (UTUC) (2017) (0)
- Abstract 01: Genetic variation within genes related to telomere maintenance and DNA repair in a cohort of pediatric acute myeloid leukemia (AML) subjects (2014) (0)
- Assessing structural variation in a personal genome—towards a human reference diploid genome (2015) (0)
- The Pan-Cancer Genome Atlas (2014) (0)
- ASSESSING THE UTILITY OF CLINICAL TUMOR SEQUENCING IN THE PEDIATRIC NEURO-ONCOLOGY CLINIC (2014) (0)
- Abstract PR04: Novel somatic and germline mutations in intracranial germ cell tumors (2014) (0)
- Abstract 3841: A hybrid mapping approach improves genomic and transcriptomic analysis of patient derived orthotropic xenograft (PDOX) models of pediatric CNS tumors (2017) (0)
- Abstract 5589: Molecular signatures of in vitro drug response in lung cancer. (2013) (0)
- Abstract 484: Fidelity of subclonal representation in human neuroblastoma-derived cell line and patient-derived xenograft models: A report from the NCI-TARGET project (2015) (0)
- Abstract IA12: Developing precision medicine-based new lung cancer therapeutics (2018) (0)
- Genomic Sequencing Reveals Novel Mutations In Hepatitis C-Associated Hepatocellular Carcinoma (2011) (0)
- Abstract 136: Refining the molecular profile of colorectal tumors to expand prevention and treatment opportunities (2016) (0)
- Abstract 1286: Targeted deep sequencing of colorectal tumor tissues to study associations of tumor subtypes with germline genetic, lifestyle, and environmental risk factors (2017) (0)
- The complete DNA sequence of the human dystrophin gene (2002) (0)
- Abstract 4600: Target exome sequencing for disease-causing rare mutations in familial and sporadic lung cancer (2015) (0)
- Ap proach for Mutation Calling of Tumor Exomes Using Multiple Genomic Pipelines Graphical (0)
- Author Correction: The evolutionary history of 2,658 cancers (2023) (0)
- 170 Gene expression profiling and immune cell-type deconvolution highlight robust disease progression and survival markers in multiple cohorts of CTCL patients (2018) (0)
- Whole Exome Analysis Reveals Key Genomic Differences between Sporadic and Endemic Pediatric Burkitt Lymphoma (2018) (0)
- Author Correction: Patterns of somatic structural variation in human cancer genomes (2020) (0)
- Abstract 1525: Exome sequencing to identify permissive mutations representing acquired vulnerabilities in lung cancer (2014) (0)
- Abstract P6-11-01: A broad spectrum therapeutic strategy for TNBC revealed by a new pathway that coordinates oncogenic RTKs (2015) (0)
- Abstract LB-355: Whole-exome sequencing of intracranial germ cell tumors reveals frequent mutations in KIT and RAS pathways and histone demethylases. (2013) (0)
- Abstract S6-10: Identification of a Novel Tumor Suppressor Network Reveals a Role for Proto-Oncogenic Receptor Tyrosine Kinases in Triple-Negative Breast Cancer (2010) (0)
- Abstract LB-311: Whole-exome sequencing of polycythemia vera revealed novel driver genes and somatic mutation shared by T cells and granulocytes (2014) (0)
- GENE-04. PEDIATRIC MALIGNANT EPITHELIOID GLIONEURONAL TUMOR: PATHOLOGICAL, CLINICAL, AND MOLECULAR CHARACTERIZATION OF A RARE AND DEADLY MALIGNANCY (2017) (0)
- Author Correction: Inferring structural variant cancer cell fraction (2022) (0)
- Abstract 2029: Identification of novel tumor suppressor microRNAs implicated in epithelial ovarian cancer from the 19q13.41 non-coding RNA cluster (2010) (0)
- Abstract 737: Clonal evolution of the HER2 L755S mutation as a mechanism of acquired HER-targeted therapy resistance (2015) (0)
- Abstract 1662:In vivodrug response evaluation in anaplastic thyroid cancer patient-derived tumor xenografts following high-throughput screening (2020) (0)
- Supplementary Materials for Landscape of Somatic Retrotransposition in Human Cancers (2012) (0)
- The PDZ adaptor protein, NHERF1, organizes and regulates protein complexes at the cell membrane (2010) (0)
- Abstract 4877: Transcriptome sequencing of pediatric hepatocellular carcinoma reveals genomic events involvingAPCandTERT (2017) (0)
- Abstract 958: Early hepatocellular carcinoma as another entity from classical hepatocellular carcinoma by integrated genomic analysis (2015) (0)
- Abstract 2218: Whole exome DNA sequencing in human cancers of the digestive system (2010) (0)
- Abstract A14: Can mutation profile be of help to define the cellular origin of ampullary adenocarcinoma? (2012) (0)
- Abstract 4922: Patterns of tumor evolution in high grade serous ovarian carcinoma (2012) (0)
- A New Take on Uptake: Dopamine Transporters and the Cellular Mechanisms of Amphetamine Action (2013) (0)
- Abstract 5169: Diagnostic yield of clinical tumor and germline exome sequencing for newly diagnosed children with solid tumors (2014) (0)
- TBIO-20. CLINICAL TUMOR WHOLE EXOME SEQUENCING FOR PEDIATRIC NEURO-ONCOLOGY PATIENTS – RESULTS FROM THE BAYLOR ADVANCING SEQUENCING IN CHILDHOOD CANCER CARE (BASIC3) CLINICAL SEQUENCING STUDY (2018) (0)
- Abstract 1920: Novel molecular targets for chemoprevention of squamous cell carcinoma (2015) (0)
- Neutral tumor evolution? (2018) (0)
- Abstract PD15-03: Overlapping molecular features (proliferation, immune signatures andTP53mutations) associated with palbociclib resistance inER+HER2- primary breast cancer (2022) (0)
- Inferring structural variant cancer cell fraction (2020) (0)
- The evolutionary history of 2,658 cancers (2020) (0)
- SQUAMOUS CELL CARCINOMA OF THE ORAL TONGUE IN YOUNG NON-SMOKERS IS GENOMICALLY SIMILAR TO TUMORS IN OLDER PATIENTS WITH A HISTORY OF SMOKING (2014) (0)
- P3-210 ApoE4-associated accumulation of cholesterol and ceramide in the brains of Alzheimer’s patients (2006) (0)
- New Found Association Between Mutated Tumor Suppressive Gene And Non-Hepatitis C Hepatocellular Carcinoma (2011) (0)
- HG-48INTEGRATED SEQUENCING OF PEDIATRIC PILOCYTIC ASTROCYTOMA WITH ANAPLASIA REVEALS MOLECULAR FEATURES OF BOTH LOW AND HIGH-GRADE GLIAL TUMORS (2016) (0)
- Abstract 5113: Functional analysis of genomic variants identified through whole exome sequencing for susceptibility to lymphocytic leukemia (2012) (0)
- Author Correction: Inferring structural variant cancer cell fraction (2022) (0)
- Functional Analysis of Sequence Variation Resequencing of IRS 2 reveals rare variants for obesity but not fasting glucose homeostasis in Hispanic children (2011) (0)
- Author Correction: Analyses of non-coding somatic drivers in 2,658 cancer whole genomes (2020) (0)
- Detection and characterization of constitutive replication origins defined by DNA polymerase epsilon (2023) (0)
- Abstract 5167: Identification of inactivating mutations in stepwise hepatocarcinogenesis using next generation sequencer (2014) (0)
- Abstract B011: Immunoediting in untreated mismatch repair deficient colorectal cancer (2018) (0)
- Author Correction: Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples (2020) (0)
- Abstract 2211: Viral subtypes in hepatocellular carcinoma are associated with different mechanisms of WNT/CTNNB1 alteration (2014) (0)
- Orphan Nuclear Receptor GCNF Is Required for the Repression ofPluripotency Genes during Retinoic Acid-Induced EmbryonicStem Cell Differentiation (2005) (0)
- Abstract 4020: Genome-wide analysis of stepwise hepatocarcinogenesis using next generation sequencer. (2013) (0)
- Abstract 567: Comparative mining of normal and tumor tissue RNAseq gene expression datasets to define expression-based neo-antigens (2019) (0)
- SVachra: a tool to identify genomic structural variation in mate pair sequencing data containing inward and outward facing reads (2017) (0)
- Abstract LB-180: The genetic landscape of Wilms tumor (2016) (0)
- Whole genome sequencing of sporadic Burkitt lymphoma in HIV-infected and uninfected patients. (2013) (0)
- HIGH GRADE GLIOMAS AND DIPG (2014) (0)
- Integrative Genomic Analy sis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles Graphical (2017) (0)
- Abstract 998: Rise and fall of subclones from diagnosis to relapse in pediatric B-acute lymphoblastic leukemia (B-ALL): A report from the children's oncology group (COG) - Target - St. Jude Pediatric Cancer Genome Project (2014) (0)
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What Schools Are Affiliated With David A. Wheeler?
David A. Wheeler is affiliated with the following schools:
