David Y. Thomas
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Engineering Computer Science
David Y. Thomas's Degrees
- PhD Computer Science Stanford University
- Masters Electrical Engineering University of California, Berkeley
- Bachelors Computer Engineering University of California, Berkeley
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(Suggest an Edit or Addition)David Y. Thomas's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Association of folding intermediates of glycoproteins with calnexin during protein maturation (1993) (533)
- Calnexin: a membrane-bound chaperone of the endoplasmic reticulum. (1994) (519)
- A family of yeast expression vectors containing the phage f1 intergenic region. (1987) (508)
- SSR alpha and associated calnexin are major calcium binding proteins of the endoplasmic reticulum membrane. (1991) (495)
- The STE4 and STE18 genes of yeast encode potential β and γ subunits of the mating factor receptor-coupled G protein (1989) (420)
- The Structure of calnexin, an ER chaperone involved in quality control of protein folding. (2001) (396)
- Transcription profiling of Candida albicans cells undergoing the yeast-to-hyphal transition. (2002) (386)
- ERdj5 Is Required as a Disulfide Reductase for Degradation of Misfolded Proteins in the ER (2008) (371)
- Signaling through adenylyl cyclase is essential for hyphal growth and virulence in the pathogenic fungus Candida albicans. (2001) (365)
- gp25L/emp24/p24 Protein Family Members of the cis-Golgi Network Bind Both COP I and II Coatomer (1998) (355)
- Enhanced Catalysis of Ribonuclease B Folding by the Interaction of Calnexin or Calreticulin with ERp57* (1998) (343)
- Signal transduction through homologs of the Ste20p and Ste7p protein kinases can trigger hyphal formation in the pathogenic fungus Candida albicans. (1996) (321)
- Correlation between virulence of Candida albicans mutants in mice and Galleria mellonella larvae. (2002) (307)
- Enhanced secretion from insect cells of a foreign protein fused to the honeybee melittin signal peptide. (1991) (280)
- Htm1p, a mannosidase‐like protein, is involved in glycoprotein degradation in yeast (2001) (265)
- Protein quality control in the ER: the recognition of misfolded proteins. (2010) (258)
- Interaction of a G-protein β-subunit with a conserved sequence in Ste20/PAK family protein kinases (1998) (253)
- A Role for Myosin-I in Actin Assembly through Interactions with Vrp1p, Bee1p, and the Arp2/3 Complex (2000) (252)
- Pheromone signalling and polarized morphogenesis in yeast. (1997) (243)
- Proteomics Characterization of Abundant Golgi Membrane Proteins* (2001) (239)
- Virulence and hyphal formation of Candida albicans require the Ste20p-like protein kinase CaCla4p (1997) (210)
- Localization of the Lectin, ERp57 Binding, and Polypeptide Binding Sites of Calnexin and Calreticulin* (2002) (206)
- Functional complementation of yeast ste6 by a mammalian multidrug resistance mdr gene. (1992) (204)
- Ca2+ Regulation of Interactions between Endoplasmic Reticulum Chaperones* (1999) (202)
- Drag&Drop cloning in yeast. (2005) (193)
- Conformation-Independent Binding of Monoglucosylated Ribonuclease B to Calnexin (1997) (189)
- Association of the yeast pheromone response G protein beta gamma subunits with the MAP kinase scaffold Ste5p. (1995) (185)
- Erp1p and Erp2p, partners for Emp24p and Erv25p in a yeast p24 complex. (1999) (181)
- Lectin control of protein folding and sorting in the secretory pathway. (2003) (180)
- Yeast KEX1 gene encodes a putative protease with a carboxypeptidase B-like function involved in killer toxin and α-factor precursor processing (1987) (175)
- Cold adaptation in budding yeast. (2004) (174)
- Saccharomyces cerevisiae CNE1 Encodes an Endoplasmic Reticulum (ER) Membrane Protein with Sequence Similarity to Calnexin and Calreticulin and Functions as a Constituent of the ER Quality Control Apparatus (*) (1995) (172)
- Recombination of mitochondrial drug-resistance factors in Saccharomyces cerevisiae. (1968) (157)
- Overexpression of the STE4 gene leads to mating response in haploid Saccharomyces cerevisiae (1990) (157)
- BAP31 Interacts with Sec61 Translocons and Promotes Retrotranslocation of CFTRΔF508 via the Derlin-1 Complex (2008) (153)
- Crystal structure of the bb' domains of the protein disulfide isomerase ERp57. (2006) (145)
- Functional expression of human cathepsin S in Saccharomyces cerevisiae. Purification and characterization of the recombinant enzyme. (1993) (144)
- Population genomics of drug resistance in Candida albicans (2002) (143)
- The endoplasmic reticulum: integration of protein folding, quality control, signaling and degradation. (2001) (140)
- The ER protein folding sensor UDP-glucose glycoprotein–glucosyltransferase modifies substrates distant to local changes in glycoprotein conformation (2004) (137)
- Structural Analog of Sildenafil Identified as a Novel Corrector of the F508del-CFTR Trafficking Defect (2008) (130)
- Inhibition of mitochondrial synthesis in yeast by erythromycin: cytoplasmic and nuclear factors controlling resistance. (1968) (126)
- Contribution of the glutamine 19 side chain to transition-state stabilization in the oxyanion hole of papain. (1991) (125)
- Dominant negative selection of heterologous genes: isolation of Candida albicans genes that interfere with Saccharomyces cerevisiae mating factor-induced cell cycle arrest. (1992) (124)
- Conformational Changes Induced in the Endoplasmic Reticulum Luminal Domain of Calnexin by Mg-ATP and Ca(*) (1995) (122)
- ERp57 and PDI: multifunctional protein disulfide isomerases with similar domain architectures but differing substrate-partner associations. (2006) (121)
- Correctors of Protein Trafficking Defects Identified by a Novel High‐Throughput Screening Assay (2007) (119)
- Derepressed hyphal growth and reduced virulence in a VH1 family-related protein phosphatase mutant of the human pathogen Candida albicans. (1997) (115)
- The heterodimeric structure of glucosidase II is required for its activity, solubility, and localization in vivo. (2000) (114)
- CDC42 Is Required for Polarized Growth in Human Pathogen Candida albicans (2002) (114)
- Chemical genetic screen identifies lithocholic acid as an anti-aging compound that extends yeast chronological life span in a TOR-independent manner, by modulating housekeeping longevity assurance processes (2010) (111)
- Synthesis of human insulin gene. VIII. Construction of expression vectors for fused proinsulin production in Escherichia coli. (1984) (110)
- A protein engineering study of the role of aspartate 158 in the catalytic mechanism of papain. (1990) (110)
- Interaction of the Grb10 Adapter Protein with the Raf1 and MEK1 Kinases* (1998) (109)
- A simple method for the large-scale preparation of mitochondria from microorganisms. (1977) (108)
- Association of calnexin with mutant peripheral myelin protein-22 ex vivo: A basis for “gain-of-function” ER diseases (2002) (107)
- Characterization and small-molecule stabilization of the multisite tandem binding between 14-3-3 and the R domain of CFTR (2016) (105)
- Identification of a NBD1-binding pharmacological chaperone that corrects the trafficking defect of F508del-CFTR. (2011) (104)
- Structure and transcriptional control of the Saccharomyces cerevisiae POX1 gene encoding acyl-coenzyme A oxidase. (1990) (103)
- Refining Protein Subcellular Localization (2005) (100)
- Control of expression, glycosylation, and secretion of HIV-1 gp120 by homologous and heterologous signal sequences. (1994) (99)
- Processing of the papain precursor. Purification of the zymogen and characterization of its mechanism of processing. (1991) (99)
- Correction of the ΔPhe508 Cystic Fibrosis Transmembrane Conductance Regulator Trafficking Defect by the Bioavailable Compound Glafenine (2010) (98)
- An Interaction Map of Endoplasmic Reticulum Chaperones and Foldases* (2012) (98)
- Adaptor protein Ste50p links the Ste11p MEKK to the HOG pathway through plasma membrane association. (2006) (95)
- Depletion of a polo-like kinase in Candida albicans activates cyclase-dependent hyphal-like growth. (2003) (95)
- Candida albicans Killing by RAW 264.7 Mouse Macrophage Cells: Effects of Candida Genotype, Infection Ratios, and Gamma Interferon Treatment (2002) (93)
- Overexpression, purification, and characterization of recombinant Ca-ATPase regulators for high-resolution solution and solid-state NMR studies. (2003) (93)
- The HIV-1 Env protein signal sequence retards its cleavage and down-regulates the glycoprotein folding. (2000) (91)
- Structural Basis of Cyclophilin B Binding by the Calnexin/Calreticulin P-domain*♦ (2010) (90)
- Secretion of functional papain precursor from insect cells. Requirement for N-glycosylation of the pro-region. (1990) (89)
- Multiple 40-kDa heat-shock protein chaperones function in Tom70-dependent mitochondrial import. (2007) (89)
- Effects of inefficient cleavage of the signal sequence of HIV-1 gp 120 on its association with calnexin, folding, and intracellular transport. (1996) (87)
- Glycopeptide specificity of the secretory protein folding sensor UDP–glucose glycoprotein:glucosyltransferase (2003) (87)
- Localization of Endogenous Grb10 to the Mitochondria and Its Interaction with the Mitochondrial-associated Raf-1 Pool* (1999) (86)
- Functional characterization of the interaction of Ste50p with Ste11p MAPKKK in Saccharomyces cerevisiae. (1999) (85)
- Novel pharmacological strategies to treat cystic fibrosis. (2013) (83)
- Identifying Regulatory Subnetworks for a Set of Genes* (2005) (82)
- The STE4 and STE18 genes of yeast encode potential beta and gamma subunits of the mating factor receptor-coupled G protein. (1989) (81)
- Protein folding in a specialized compartment: the endoplasmic reticulum. (1999) (79)
- Structure of the cel-3 gene from Fibrobacter succinogenes S85 and characteristics of the encoded gene product, endoglucanase 3 (1989) (79)
- Chemogenomic profiling predicts antifungal synergies (2009) (76)
- The Yeast Proprotein Convertase Encoded by YAP3 Is a Glycophosphatidylinositol-anchored Protein That Localizes to the Plasma Membrane (*) (1995) (76)
- Myosin I Is Required for Hypha Formation in Candidaalbicans (2002) (75)
- Cysteine protease isoforms from Trypanosoma cruzi, cruzipain 2 and cruzain, present different substrate preference and susceptibility to inhibitors. (2001) (75)
- Identification of new cysteine protease gene isoforms in Trypanosoma cruzi. (1994) (73)
- Interactions among the subunits of the G protein involved in Saccharomyces cerevisiae mating (1993) (71)
- Potential for manipulation of the rumen fermentation through the use of recombinant DNA techniques. (1986) (69)
- Involvement of protein N-glycosyl chain glucosylation and processing in the biosynthesis of cell wall beta-1,6-glucan of Saccharomyces cerevisiae. (1998) (68)
- Engineering of papain: selective alteration of substrate specificity by site-directed mutagenesis. (1991) (65)
- Functional expression of P-glycoprotein in Saccharomyces cerevisiae confers cellular resistance to the immunosuppressive and antifungal agent FK520. (1994) (64)
- Low free drug concentration prevents inhibition of F508del CFTR functional expression by the potentiator VX‐770 (ivacaftor) (2016) (63)
- Cloning and characterization of mammalian UDP-glucose glycoprotein: glucosyltransferase and the development of a specific substrate for this enzyme. (2000) (63)
- Characteristics of the endoglucanase encoded by a cel gene from Bacteroides succinogenes expressed in Escherichia coli (1987) (61)
- Enhanced Ca2+ entry due to Orai1 plasma membrane insertion increases IL‐8 secretion by cystic fibrosis airways (2011) (61)
- Organization of the Sec61 translocon, studied by high resolution native electrophoresis. (2010) (60)
- PCR and DNA Fingerprinting Used as Quality Control in the Production of Wine Yeast Strains (1994) (59)
- Cloning and sequencing of the preprotoxin‐coding region of the yeast M1 double‐stranded RNA. (1984) (59)
- Ste50p sustains mating pheromone‐induced signal transduction in the yeast Saccharomyces cerevisiae (1996) (57)
- Cell Cycle- and Cln2p-Cdc28p-dependent Phosphorylation of the Yeast Ste20p Protein Kinase* (1998) (57)
- Polymorphism in the lipase genes of Geotrichum candidum strains. (1994) (56)
- Reverse Genetics in Candida albicans Predicts ARF Cycling Is Essential for Drug Resistance and Virulence (2010) (55)
- Generation of conditional lethal Candida albicans mutants by inducible deletion of essential genes (2002) (54)
- Carbamazepine as a Novel Small Molecule Corrector of Trafficking-impaired ATP-sensitive Potassium Channels Identified in Congenital Hyperinsulinism* (2013) (54)
- Genetic identification of residues involved in association of alpha and beta G-protein subunits (1994) (53)
- Purification and characterization of a chloride-stimulated cellobiosidase from Bacteroides succinogenes S85 (1988) (53)
- Structure of the noncatalytic domains and global fold of the protein disulfide isomerase ERp72. (2009) (53)
- Casein kinase II phosphorylation of signal sequence receptor alpha and the associated membrane chaperone calnexin. (1992) (52)
- Role of amino acid sequences flanking dibasic cleavage sites in precursor proteolytic processing. The importance of the first residue C-terminal of the cleavage site. (1995) (52)
- Role of amino acid sequences flanking dibasic cleavage sites in precursor proteolytic processing The importance of the first residue C-terminal of the cleavage site (1995) (52)
- Mitochondrial genetic analysis by zygote cell lineages in Saccharomyces cerevisiae. (1973) (51)
- Ibuprofen rescues mutant cystic fibrosis transmembrane conductance regulator trafficking. (2015) (50)
- Intracellular Eukaryotic Parasites Have a Distinct Unfolded Protein Response (2011) (49)
- The expression of cDNA clones of yeast M1 double‐stranded RNA in yeast confers both killer and immunity phenotypes. (1984) (49)
- Calnexin phosphorylation: linking cytoplasmic signalling to endoplasmic reticulum lumenal functions. (2010) (49)
- Conserved in Vivo Phosphorylation of Calnexin at Casein Kinase II Sites as Well as a Protein Kinase C/Proline-directed Kinase Site* (1998) (48)
- The ER glycoprotein quality control system. (2004) (48)
- Molecular cloning and organization of two leghaemoglobin genomic sequences of soybean (1981) (48)
- Nup53p is a Target of Two Mitotic Kinases, Cdk1p and Hrr25p (2007) (47)
- Genetic analysis of the interface between Cdc42p and the CRIB domain of Ste20p in Saccharomyces cerevisiae. (2003) (47)
- Modification of the electrostatic environment is tolerated in the oxyanion hole of the cysteine protease papain. (1995) (47)
- Calnexin Phosphorylation Attenuates the Release of Partially Misfolded α1-Antitrypsin to the Secretory Pathway* (2009) (46)
- Control of anterior GRadient 2 (AGR2) dimerization links endoplasmic reticulum proteostasis to inflammation (2019) (44)
- Correction of F508del-CFTR trafficking by the sponge alkaloid latonduine is modulated by interaction with PARP. (2012) (44)
- Ouabain Mimics Low Temperature Rescue of F508del-CFTR in Cystic Fibrosis Epithelial Cells (2012) (43)
- Calnexin family members as modulators of genetic diseases. (1999) (42)
- Compounds that correct F508del-CFTR trafficking can also correct other protein trafficking diseases: an in vitro study using cell lines (2013) (42)
- The Hera database and its use in the characterization of endoplasmic reticulum proteins (2004) (41)
- Screening and identification of a gene, PSE-1, that affects protein secretion in Saccharomyces cerevisiae. (1992) (41)
- Mitogen-activated protein kinase-defective Candida albicans is avirulent in a novel model of localized murine candidiasis. (1998) (40)
- Synthesis of a human insulin gene. VI. Expression of the synthetic proinsulin gene in yeast. (1983) (40)
- Determination of the carboxyl termini of the alpha and beta subunits of yeast K1 killer toxin. Requirement of a carboxypeptidase B-like activity for maturation. (1987) (40)
- Experimental Design and Statistical Methods for Improved Hit Detection in High-Throughput Screening (2010) (40)
- The expression in Escherichia coli of a synthetic gene coding for the precursor of papain is prevented by its own putative signal sequence. (1989) (39)
- Expression in yeast of a cDNA copy of the K2 killer toxin gene (1991) (38)
- Expression and Characterization of Geotrichum candidum Lipase I Gene (1995) (36)
- Specific inhibition by hGRB10ζ of insulin-induced glycogen synthase activation: evidence for a novel signaling pathway (2001) (34)
- Contribution to activity of histidine-aromatic, amide-aromatic, and aromatic-aromatic interactions in the extended catalytic site of cysteine proteinases. (1996) (34)
- Site-directed mutations altering the CAAX box of Ste18, the yeast pheromone-response pathway G gamma subunit. (1994) (33)
- Correctors of the basic trafficking defect of the mutant F508del-CFTR that causes cystic fibrosis. (2013) (32)
- Importance of hydrogen-bonding interactions involving the side chain of Asp158 in the catalytic mechanism of papain. (1991) (32)
- Expression of functional papain precursor in Saccharomyces cerevisiae: rapid screening of mutants. (1993) (31)
- Saccharomyces cerevisiae plasmid, Scp or 2 mum: intracellular distribution, stability and nucleosomal-like packaging. (1980) (30)
- Drosophila melanogaster Thor and Response to Candida albicans Infection (2007) (30)
- Rho5p Is Involved in Mediating the Osmotic Stress Response in Saccharomyces cerevisiae, and Its Activity Is Regulated via Msi1p and Npr1p by Phosphorylation and Ubiquitination (2008) (29)
- GeneExpression in HL60 Granulocytoids and Human PolymorphonuclearLeukocytes Exposed to Candidaalbicans† (2004) (28)
- Cloning and expression of Geotrichum candidum lipase II gene in yeast. Probing of the enzyme active site by site-directed mutagenesis. (1993) (27)
- Escherichia coli plasmid vectors containing synthetic translational initiation sequences and ribosome binding sites fused with the lacZ gene. (1982) (26)
- Products of mitochondrial protein synthesis in yeast. (1971) (26)
- Expression and characterization of Geotrichum candidum lipase I gene. Comparison of specificity profile with lipase II. (1995) (25)
- Functional Characterization of Myosin I Tail Regions in Candida albicans (2004) (25)
- Corrector combination therapies for F508del-CFTR. (2017) (25)
- A novel triple combination of pharmacological chaperones improves F508del-CFTR correction (2018) (24)
- The dual phosphodiesterase 3 and 4 inhibitor RPL554 stimulates CFTR and ciliary beating in primary cultures of bronchial epithelia. (2016) (24)
- Unravelling druggable signalling networks that control F508del-CFTR proteostasis (2015) (24)
- Latonduine Analogs Restore F508del–Cystic Fibrosis Transmembrane Conductance Regulator Trafficking through the Modulation of Poly-ADP Ribose Polymerase 3 and Poly-ADP Ribose Polymerase 16 Activity (2016) (24)
- The Kex2p proregion is essential for the biosynthesis of an active enzyme and requires a C-terminal basic residue for its function. (2000) (23)
- Cleavage of prosomatostatins by the yeast Yap3 and Kex2 endoprotease. (1994) (23)
- The role of the lectin calnexin in conformation independent binding to N-linked glycoproteins and quality control. (1998) (23)
- Molecular and phenotypic characterization of penicillinase-producing Neisseria gonorrhoeae from Canadian sources (1981) (22)
- Expression, purification, and characterization of the yeast KEX1 gene product, a polypeptide precursor processing carboxypeptidase. (1993) (22)
- The kalilo senescence plasmid of Neurospora intermedia has covalently-linked 5′ terminal proteins (1990) (21)
- Structure of the catalytic a(0)a fragment of the protein disulfide isomerase ERp72. (2010) (21)
- The yeast KEX-2-processing endoprotease is active in the Golgi apparatus of transfected NIH 3T3 fibroblasts. (1990) (21)
- Genetic and molecular approaches to synthesis and action of the yeast killer toxin (1990) (20)
- Crystal structure of Kex1deltap, a prohormone-processing carboxypeptidase from Saccharomyces cerevisiae,. (1997) (19)
- Heterologous expression of peptide hormone precursors in the yeast Saccharomyces cerevisiae. Evidence for a novel prohormone endoprotease with specificity for monobasic amino acids. (1991) (19)
- Constitutive activation of the Saccharomyces cerevislae mating response pathway by a MAP kinase kinase from Candida albicans (1995) (19)
- Ubiquitin gene expression: response to environmental changes (1991) (19)
- An effective transformation method for Hansenula polymorpha (1990) (18)
- Redesigning the active site of Geotrichum candidum lipase. (1995) (18)
- Variable Responses to CFTR Correctors in vitro: Estimating the Design Effect in Precision Medicine (2018) (18)
- Lectins of the ER quality control machinery. (2001) (18)
- Synthesis of mitochondrial proteins in an Escherichia coli cell-free system directed by yeast mitochondrial DNA. (1975) (18)
- Cloning of Saccharomyces cerevisiae STE5 as a suppressor of a Ste20 protein kinase mutant: structural and functional similarity of Ste5 to Farl (1993) (16)
- Decreasing Poly(ADP-Ribose) Polymerase Activity Restores ΔF508 CFTR Trafficking (2012) (16)
- Prohormone processing by yeast proteases. (1991) (16)
- Proteomics Identifies Golgi phosphoprotein 3 (GOLPH3) with A Link Between Golgi Structure, Cancer, DNA Damage and Protection from Cell Death* (2017) (15)
- Cigarette smoke activates CFTR through ROS-stimulated cAMP signaling in human bronchial epithelial cells. (2018) (14)
- Expression of the Saccharomyces cerevisiae Kex2p endoprotease in insect cells (1992) (14)
- Molecular interactions of the Gbeta binding domain of the Ste20p/PAK family of protein kinases. An isolated but fully functional Gbeta binding domain from Ste20p is only partially folded as shown by heteronuclear NMR spectroscopy. (2001) (14)
- Bright stable luminescent yeast using bacterial luciferase as a sensor. (2003) (14)
- A Covalent Cysteine‐Targeting Kinase Inhibitor of Ire1 Permits Allosteric Control of Endoribonuclease Activity (2016) (12)
- Characterization of the Mechanism of Action of RDR01752, a Novel Corrector of F508del-CFTR. (2020) (12)
- The anion transporter SLC26A9 localizes to tight junctions and is degraded by the proteasome when co-expressed with F508del–CFTR (2019) (11)
- Intracellular proteolytic processing of proopiomelanocortin in heterologous COS-1 cells by the yeast KEX2 endoprotease. (1990) (11)
- Phosphorylation of the MAPKKK Regulator Ste50p in Saccharomyces cerevisiae: a Casein Kinase I Phosphorylation Site Is Required for Proper Mating Function (2003) (11)
- Removal of an inter-domain hydrogen bond through site-directed mutagenesis: role of serine 176 in the mechanism of papain. (1991) (11)
- The dual phosphodiesterase 3/4 inhibitor RPL554 stimulates rare class III and IV CFTR mutants. (2020) (11)
- PCR-assisted mutagenesis for site-directed insertion/deletion of large DNA segments. (1996) (11)
- Genetic interactions indicate a role for Mdg1p and the SH3 domain protein Bem1p in linking the G-protein mediated yeast pheromone signalling pathway to regulators of cell polarity (1996) (11)
- Mutagenesis of Ste18, a putative G gamma subunit in the Saccharomyces cerevisiae pheromone response pathway. (1992) (10)
- Combination of Selective PARP3 and PARP16 Inhibitory Analogues of Latonduine A Corrects F508del-CFTR Trafficking (2020) (10)
- Expression of MFα1 in MATa cells supersensitive to α-factor leads to self-arrest (1988) (8)
- Identification and crystallization of a protease-resistant core of calnexin that retains biological activity. (1998) (8)
- Secretion, purification and characterization of a soluble form of the yeast KEX1-encoded protein from insect-cell cultures. (1994) (7)
- Cystic Fibrosis: Proteostatic correctors of CFTR trafficking and alternative therapeutic targets. (2019) (6)
- A yeast transcription system for the 5S rRNA gene. (1982) (6)
- 1H, 13C and 15N resonance assignments of the bb′ domains of human protein disulfide isomerase (2007) (6)
- Genetic analysis of Saccharomyces cerevisiae transformed by plasmid containing a supressor transfer ribonucleic acid gene (1980) (5)
- DePIE: Designing Primers for Protein Interaction Experiments (2003) (5)
- Rescue of Mutant CFTR Trafficking Defect by the Investigational Compound MCG1516A (2022) (5)
- Cyclic nucleotide phosphodiesterase inhibitors as therapeutic interventions for cystic fibrosis. (2021) (5)
- Dominant Negative Selection of Heterologous Genes in Yeast (1993) (5)
- Experimental Variation of the Number of Mitochondrial Genomes Participating in Mitochondrial Genetics (1976) (5)
- Expression of the Saccharomyces cerevisiae Kex2p endoprotease in inset cells. Evidence for a carboxy-terminal autoprocessing event. (1992) (5)
- Expression of MF alpha 1 in MATa cells supersensitive to alpha-factor leads to self-arrest. (1988) (5)
- A yeast mutant with temperature-sensitive mitochondrial ribosomes. (1973) (5)
- Macrocycle-stabilization of its interaction with 14-3-3 increases plasma membrane localization and activity of CFTR (2022) (5)
- The Roles of Calnexin and Calreticulin as Endoplasmic Reticulum Molecular Chaperones (1996) (4)
- Products of mitochondrial protein synthesis in yeast. (1971) (4)
- Cloning and characterization of the SKI3 gene of Saccharomyces cerevisiae demonstrates allelism to SKI5 (1989) (4)
- Protein Trafficking Diseases: Small Molecule Approaches (2008) (3)
- Alternative Splicing of a Receptor Intracellular Domain Yields Different Ectodomain Conformations, Enabling Isoform-Selective Functional Ligands (2020) (3)
- Nonspecific binding of common anti-CFTR antibodies in ciliated cells of human airway epithelium (2021) (3)
- A Biochemical Genomics Screen for Substrates of Ste20p Kinase Enables the In Silico Prediction of Novel Substrates (2009) (3)
- PCR-assisted large insertion/deletion mutagenesis. (1993) (2)
- The characteristics and cloning of bacterial cellulases. (1986) (2)
- Regulation of Receptor Trafficking by Rab GTPases (2003) (1)
- Functional expression of P-glycoprotein in Saccharomyces cerevisiae confers cellular resistance to the immunosuppressive and antifungal agent FK520 (1994) (1)
- CORRECTORS OF PROTEIN TRAFFICKING DEFECTS (2017) (1)
- Transformation of Saccharomyces cerevisiae with plasmids containing fragments of yeast 2 μ DNA and a suppressor tRNA gene (1980) (1)
- Synthesis of cytochromec oxidase polypeptides in anEscherichia coli cell-free system directed bySaccharomyces cerevisiae mitochondrial DNA (1977) (1)
- Expression of Hepatitis B Virus Surface Antigen Gene in Mammalian, Yeast, and Insect Cells (1988) (1)
- Phosphodiesterase 8A Regulates CFTR Activity in Airway Epithelial Cells. (2021) (1)
- The NSAID glafenine rescues class 2 CFTR mutants via cyclooxygenase 2 inhibition of the arachidonic acid pathway (2022) (1)
- Latonduine analogues restore F508del-CFTR trafficking through the modulation of PARP-3 and PARP-16 activity. (2016) (1)
- The Synthesis of Yeast Mitochondrial Proteins in Cell-free Systems (1976) (1)
- Molecular Interactions of the Gβ Binding Domain of the Ste20p/PAK Family of Protein Kinases (2001) (1)
- A novel triple combination of pharmacological chaperones improves F508del-CFTR correction (2018) (0)
- Author response: Unravelling druggable signalling networks that control F508del-CFTR proteostasis (2015) (0)
- Calnexin, an ER Integral Membrane Chaperone in Health and Disease (2003) (0)
- Protein targeting and protein secretion. (1989) (0)
- COPD and the modulation of CFTR by acute exposure to cigarette smoke. (2022) (0)
- Chaperones in the Endoplasmic Reticulum (ER): Function and Interaction Network (2014) (0)
- Genetics , Biogenesis and Bioenergetics of Mitochondria (2012) (0)
- Proteomic Analysis of Rough and Smooth Endoplasmic Reticulum (2002) (0)
- Cold Adaptation in Budding Yeast□D (2004) (0)
- Ionocyte-Specific Regulation of CFTR. (2023) (0)
- Yeast Two‐hybrid Technologies (2008) (0)
- Protein Trafficking Diseases (2012) (0)
- Temperature and the fertility of wild types in Neurospora (1966) (0)
- PCR-based unidirectional deletion method for creation of comprehensive cDNA libraries. (2005) (0)
- CHROMATIN STRUCTURE AND INTRACELLULAR LOCATION OF THE YEAST PLASMID Scp or 2μm DNA (1981) (0)
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