Davy Guillarme

Davy Guillarme's AcademicInfluence.com Rankings

Davy Guillarme

Chemistry

#4587

World Rank

#5671

Historical Rank

Analytical Chemistry

#196

World Rank

#203

Historical Rank

chemistry Degrees

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Chemistry

Davy Guillarme's Degrees

PhD Analytical Chemistry University of Geneva
Masters Analytical Chemistry University of Geneva

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Davy Guillarme's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Fast analysis in liquid chromatography using small particle size and high pressure. (2006) (315)
New trends in fast and high-resolution liquid chromatography: a critical comparison of existing approaches (2010) (264)
Modern analytical supercritical fluid chromatography using columns packed with sub-2 μm particles: a tutorial. (2014) (218)
Theory and practice of size exclusion chromatography for the analysis of protein aggregates. (2014) (208)
Method transfer for fast liquid chromatography in pharmaceutical analysis: application to short columns packed with small particle. Part II: gradient experiments. (2008) (193)
Effect of temperature in reversed phase liquid chromatography. (2004) (189)
Coupling ultra-high-pressure liquid chromatography with mass spectrometry (2010) (181)
Chromatographic, Electrophoretic, and Mass Spectrometric Methods for the Analytical Characterization of Protein Biopharmaceuticals. (2016) (181)
Supercritical fluid chromatography in pharmaceutical analysis. (2015) (177)
Comparison of ultra-high performance supercritical fluid chromatography and ultra-high performance liquid chromatography for the analysis of pharmaceutical compounds. (2012) (175)
Ion-exchange chromatography for the characterization of biopharmaceuticals. (2015) (163)
Intact protein analysis in the biopharmaceutical field. (2011) (159)
Recent developments in liquid chromatography--impact on qualitative and quantitative performance. (2007) (154)
Current and future trends in UHPLC (2014) (140)
Coupling ultra high-pressure liquid chromatography with mass spectrometry: constraints and possible applications. (2013) (129)
A systematic investigation of the effect of sample diluent on peak shape in hydrophilic interaction liquid chromatography. (2010) (128)
New trends in reversed-phase liquid chromatographic separations of therapeutic peptides and proteins: theory and applications. (2012) (126)
Method development for the separation of monoclonal antibody charge variants in cation exchange chromatography, Part I: salt gradient approach. (2015) (125)
Method transfer for fast liquid chromatography in pharmaceutical analysis: application to short columns packed with small particle. Part I: isocratic separation. (2007) (123)
High throughput liquid chromatography with sub-2 microm particles at high pressure and high temperature. (2007) (122)
Strategies for formulating and delivering poorly water-soluble drugs (2015) (117)
Adding a new separation dimension to MS and LC-MS: What is the utility of ion mobility spectrometry? (2018) (115)
Determination of isoelectric points and relative charge variants of 23 therapeutic monoclonal antibodies. (2017) (114)
Importance of instrumentation for fast liquid chromatography in pharmaceutical analysis. (2014) (113)
Chromatographic behaviour and comparison of column packed with sub-2 microm stationary phases in liquid chromatography. (2006) (108)
Therapeutic drug monitoring of seven psychotropic drugs and four metabolites in human plasma by HPLC-MS. (2009) (106)
Analytical strategies for the characterization of therapeutic monoclonal antibodies (2013) (106)
Evaluation of various HILIC materials for the fast separation of polar compounds. (2010) (105)
Analysis of basic compounds by supercritical fluid chromatography: attempts to improve peak shape and maintain mass spectrometry compatibility. (2012) (105)
UPLC-TOF-MS for plant metabolomics: a sequential approach for wound marker analysis in Arabidopsis thaliana. (2008) (99)
Coupling state-of-the-art supercritical fluid chromatography and mass spectrometry: from hyphenation interface optimization to high-sensitivity analysis of pharmaceutical compounds. (2014) (95)
Optimized liquid chromatography-mass spectrometry approach for the isolation of minor stress biomarkers in plant extracts and their identification by capillary nuclear magnetic resonance. (2008) (93)
Maximizing kinetic performance in supercritical fluid chromatography using state-of-the-art instruments. (2013) (93)
Quantification of glucuronidated and sulfated steroids in human urine by ultra-high pressure liquid chromatography quadrupole time-of-flight mass spectrometry (2011) (89)
Direct identification of rituximab main isoforms and subunit analysis by online selective comprehensive two-dimensional liquid chromatography-mass spectrometry. (2015) (85)
Hydrophobic interaction chromatography for the characterization of monoclonal antibodies and related products. (2016) (85)
Ultra high performance supercritical fluid chromatography coupled with tandem mass spectrometry for screening of doping agents. II: Analysis of biological samples. (2015) (82)
Method development for the separation of monoclonal antibody charge variants in cation exchange chromatography, Part II: pH gradient approach. (2015) (78)
Practical constraints in the kinetic plot representation of chromatographic performance data: theory and application to experimental data. (2006) (78)
Kinetic evaluation of new generation of column packed with 1.3 μm core-shell particles. (2013) (76)
Evaluation of a new wide pore core-shell material (Aeris WIDEPORE) and comparison with other existing stationary phases for the analysis of intact proteins. (2012) (75)
The use of columns packed with sub-2 µm particles in supercritical fluid chromatography (2014) (75)
Improved quality-by-design compliant methodology for method development in reversed-phase liquid chromatography. (2013) (73)
Analytical tools for the physicochemical profiling of drug candidates to predict absorption/distribution (2009) (72)
Comparison of originator and biosimilar therapeutic monoclonal antibodies using comprehensive two-dimensional liquid chromatography coupled with time-of-flight mass spectrometry (2016) (70)
High throughput qualitative analysis of polyphenols in tea samples by ultra-high pressure liquid chromatography coupled to UV and mass spectrometry detectors. (2010) (68)
An Online Four-Dimensional HIC×SEC-IM×MS Methodology for Proof-of-Concept Characterization of Antibody Drug Conjugates. (2018) (67)
The effect of pressure and mobile phase velocity on the retention properties of small analytes and large biomolecules in ultra-high pressure liquid chromatography. (2012) (66)
Screening of the most relevant parameters for method development in ultra-high performance hydrophilic interaction chromatography. (2013) (66)
Potential of hydrophilic interaction chromatography for the analytical characterization of protein biopharmaceuticals. (2016) (66)
Characterization of 30 therapeutic antibodies and related products by size exclusion chromatography: Feasibility assessment for future mass spectrometry hyphenation. (2017) (65)
Systematic comparison of sensitivity between hydrophilic interaction liquid chromatography and reversed phase liquid chromatography coupled with mass spectrometry. (2013) (65)
Hydrophilic Interaction Chromatography Hyphenated with Mass Spectrometry: A Powerful Analytical Tool for the Comparison of Originator and Biosimilar Therapeutic Monoclonal Antibodies at the Middle-up Level of Analysis. (2017) (64)
Ultra high performance supercritical fluid chromatography coupled with tandem mass spectrometry for screening of doping agents. I: Investigation of mobile phase and MS conditions. (2015) (64)
Development of Comprehensive Online Two-Dimensional Liquid Chromatography/Mass Spectrometry Using Hydrophilic Interaction and Reversed-Phase Separations for Rapid and Deep Profiling of Therapeutic Antibodies. (2018) (62)
Ultra high pressure liquid chromatography for crude plant extract profiling. (2011) (62)
Evaluation of columns packed with shell particles with compounds of pharmaceutical interest. (2012) (61)
Comparison of the most recent chromatographic approaches applied for fast and high resolution separations: Theory and practice. (2015) (61)
Retention modeling and method development in hydrophilic interaction chromatography. (2014) (61)
Some solutions to obtain very efficient separations in isocratic and gradient modes using small particles size and ultra-high pressure. (2009) (61)
Metabolite profiling of plant extracts by ultra-high-pressure liquid chromatography at elevated temperature coupled to time-of-flight mass spectrometry. (2009) (61)
Impact of mobile phase temperature on recovery and stability of monoclonal antibodies using recent reversed-phase stationary phases. (2012) (61)
Practical method transfer from high performance liquid chromatography to ultra-high performance liquid chromatography: the importance of frictional heating. (2011) (60)
Recent Advances in Chromatography for Pharmaceutical Analysis. (2018) (60)
Hyphenation of size exclusion chromatography to native ion mobility mass spectrometry for the analytical characterization of therapeutic antibodies and related products. (2018) (60)
Applicability of supercritical fluid chromatography - mass spectrometry to metabolomics. I - Optimization of separation conditions for the simultaneous analysis of hydrophilic and lipophilic substances. (2018) (57)
A systematic investigation of sample diluents in modern supercritical fluid chromatography. (2017) (57)
Applications of hydrophilic interaction chromatography to amino acids, peptides, and proteins. (2015) (57)
Aminoglycoside analysis in food of animal origin with a zwitterionic stationary phase and liquid chromatography-tandem mass spectrometry. (2015) (57)
Ultra-high-performance liquid chromatography for the characterization of therapeutic proteins (2014) (55)
Detection Modes with High Temperature Liquid Chromatography—A Review (2005) (55)
What are the current solutions for interfacing supercritical fluid chromatography and mass spectrometry? (2018) (54)
Analytical aspects in doping control: challenges and perspectives. (2011) (53)
New prostaglandin analog formulation for glaucoma treatment containing cyclodextrins for improved stability, solubility and ocular tolerance. (2015) (53)
Evaluation of size exclusion chromatography columns packed with sub-3μm particles for the analysis of biopharmaceutical proteins. (2017) (52)
Coupling ultra high-pressure liquid chromatography with single quadrupole mass spectrometry for the analysis of a complex drug mixture. (2009) (52)
Evaluation and comparison of various separation techniques for the analysis of closely-related compounds of pharmaceutical interest. (2013) (52)
Liquid chromatography and supercritical fluid chromatography as alternative techniques to gas chromatography for the rapid screening of anabolic agents in urine. (2016) (51)
Critical evaluation of fast size exclusion chromatographic separations of protein aggregates, applying sub-2 μm particles. (2013) (51)
Prediction of retention time in reversed-phase liquid chromatography as a tool for steroid identification. (2016) (50)
Ultra-high performance supercritical fluid chromatography coupled with quadrupole-time-of-flight mass spectrometry as a performing tool for bioactive analysis. (2016) (50)
Evaluation of recent very efficient wide-pore stationary phases for the reversed-phase separation of proteins. (2012) (49)
Protocols for the analytical characterization of therapeutic monoclonal antibodies. II - Enzymatic and chemical sample preparation. (2017) (49)
Relation between the particle size distribution and the kinetic performance of packed columns. Application to a commercial sub-2 microm particle material. (2007) (48)
Practical method development for the separation of monoclonal antibodies and antibody-drug-conjugate species in hydrophobic interaction chromatoraphy, part 2: Optimization of the phase system. (2016) (48)
Fast chiral separation of drugs using columns packed with sub-2 microm particles and ultra-high pressure. (2009) (48)
Supercritical fluid chromatography – Mass spectrometry: Recent evolution and current trends (2019) (48)
Analysis of recombinant monoclonal antibodies by RPLC: toward a generic method development approach. (2012) (48)
Fast and sensitive supercritical fluid chromatography - tandem mass spectrometry multi-class screening method for the determination of doping agents in urine. (2016) (47)
Comparison of columns packed with porous sub-2 microm particles and superficially porous sub-3 microm particles for peptide analysis at ambient and high temperature. (2010) (47)
Validation of chiral capillary electrophoresis‐electrospray ionization‐mass spectrometry methods for ecstasy and methadone in plasma (2008) (46)
Analytical strategies for the determination of amino acids: Past, present and future trends. (2019) (45)
Current possibilities of liquid chromatography for the characterization of antibody‐drug conjugates (2018) (45)
UHPLC determination of catechins for the quality control of green tea. (2014) (45)
Glycosylation of biosimilars: Recent advances in analytical characterization and clinical implications. (2019) (44)
Analysis of antibody-drug conjugates by comprehensive on-line two-dimensional hydrophobic interaction chromatography x reversed phase liquid chromatography hyphenated to high resolution mass spectrometry. I - Optimization of separation conditions. (2016) (44)
Monoclonal antibody N-glycosylation profiling using capillary electrophoresis - Mass spectrometry: Assessment and method validation. (2018) (43)
Evaluation of various chromatographic approaches for the retention of hydrophilic compounds and MS compatibility. (2013) (42)
Optimization of the coupling of high-temperature liquid chromatography and flame ionization detection application to the separations of alcohols. (2005) (42)
Contribution of various types of liquid chromatography-mass spectrometry instruments to band broadening in fast analysis. (2013) (42)
Evaluation of stationary phases packed with superficially porous particles for the analysis of pharmaceutical compounds using supercritical fluid chromatography. (2014) (42)
Comparison of liquid chromatography and supercritical fluid chromatography coupled to compact single quadrupole mass spectrometer for targeted in vitro metabolism assay. (2014) (41)
Therapeutic Fc-fusion proteins: Current analytical strategies. (2020) (41)
Pharmaceutical Applications on Columns Packed with Sub-2 µm Particles (2008) (41)
Hydrophilic interaction chromatography versus reversed phase liquid chromatography coupled to mass spectrometry: effect of electrospray ionization source geometry on sensitivity. (2014) (41)
Adsorption and recovery issues of recombinant monoclonal antibodies in reversed-phase liquid chromatography. (2015) (41)
A Novel Online Four-Dimensional SEC×SEC-IM×MS Methodology for Characterization of Monoclonal Antibody Size Variants. (2018) (40)
First inter‐laboratory study of a Supercritical Fluid Chromatography method for the determination of pharmaceutical impurities (2018) (40)
Quantitative determination of salbutamol sulfate impurities using achiral supercritical fluid chromatography (2017) (40)
An inter-laboratory and inter-platform study of steroids collision cross section by traveling wave ion mobility spectrometry. (2020) (38)
Analytical Strategies for Doping Control Purposes: Needs, Challenges, and Perspectives. (2016) (38)
In vivo characterisation of a novel water-soluble Cyclosporine A prodrug for the treatment of dry eye disease. (2012) (38)
UHPLC in life sciences (2012) (37)
Microemulsion electrokinetic chromatography hyphenated to atmospheric pressure photoionization mass spectrometry (2008) (37)
Characterization of an antibody-drug conjugate by hydrophilic interaction chromatography coupled to mass spectrometry. (2018) (36)
Computer‐assisted UHPLC–MS method development and optimization for the determination of 24 antineoplastic drugs used in hospital pharmacy (2019) (36)
A multi-target screening analysis in human plasma using fast liquid chromatography-hybrid tandem mass spectrometry (Part II). (2011) (36)
The Emergence of Universal Chromatographic Methods in the Research and Development of New Drug Substances. (2019) (35)
A scoring approach for multi-platform acquisition in metabolomics. (2019) (35)
Fast log P determination by ultra-high-pressure liquid chromatography coupled with UV and mass spectrometry detections (2009) (35)
Systematic evaluation of matrix effects in supercritical fluid chromatography versus liquid chromatography coupled to mass spectrometry for biological samples. (2018) (35)
Reliability of simulated robustness testing in fast liquid chromatography, using state-of-the-art column technology, instrumentation and modelling software. (2014) (35)
High performance affinity chromatography (HPAC) as a high-throughput screening tool in drug discovery to study drug-plasma protein interactions. (2013) (34)
Antineoplastic drugs and their analysis: a state of the art review. (2017) (34)
Supercritical fluid chromatography - Mass spectrometry in metabolomics: Past, present, and future perspectives. (2020) (33)
Coupling CE with atmospheric pressure photoionization MS for pharmaceutical basic compounds: Optimization of operating parameters (2007) (33)
Peak capacity optimisation for high resolution peptide profiling in complex mixtures by liquid chromatography coupled to time-of-flight mass spectrometry: application to the Conus consors cone snail venom. (2012) (33)
High-throughput log P determination by ultraperformance liquid chromatography: a convenient tool for medicinal chemists. (2008) (33)
Enhanced method performances for conventional and chiral CE‐ESI/MS analyses in plasma (2006) (33)
Analysis of peptides and proteins using sub-2 μm fully porous and sub 3-μm shell particles. (2011) (33)
Practical method development for the separation of monoclonal antibodies and antibody-drug-conjugate species in hydrophobic interaction chromatography, part 1: optimization of the mobile phase. (2016) (33)
Influence of pressure and temperature on molar volume and retention properties of peptides in ultra-high pressure liquid chromatography. (2013) (32)
Cutting-edge multi-level analytical and structural characterization of antibody-drug conjugates: present and future (2019) (32)
Possibilities of new generation columns packed with 1.3μm core-shell particles in gradient elution mode. (2013) (32)
Method development for pharmaceutics: some solutions for tuning selectivity in reversed phase and hydrophilic interaction liquid chromatography. (2012) (32)
Utility of a high coverage phenyl-bonding and wide-pore superficially porous particle for the analysis of monoclonal antibodies and related products. (2018) (31)
Systematic comparison of a new generation of columns packed with sub-2 μm superficially porous particles. (2014) (31)
Protocols for the analytical characterization of therapeutic monoclonal antibodies. I - Non-denaturing chromatographic techniques. (2017) (31)
Characterization of cation exchanger stationary phases applied for the separations of therapeutic monoclonal antibodies. (2015) (31)
Rational and Efficient Preparative Isolation of Natural Products by MPLC-UV-ELSD based on HPLC to MPLC Gradient Transfer (2015) (30)
Unraveling the mysteries of modern size exclusion chromatography - the way to achieve confident characterization of therapeutic proteins. (2018) (30)
Systematic evaluation of mobile phase additives for the LC-MS characterization of therapeutic proteins. (2015) (28)
Utility of dry load injection for an efficient natural products isolation at the semi-preparative chromatographic scale. (2019) (28)
Estimation of pressure-, temperature- and frictional heating-related effects on proteins' retention under ultra-high-pressure liquid chromatographic conditions. (2015) (28)
Impact of organic modifier and temperature on protein denaturation in hydrophobic interaction chromatography. (2016) (28)
Systematic evaluation of matrix effects in hydrophilic interaction chromatography versus reversed phase liquid chromatography coupled to mass spectrometry. (2016) (28)
Possibilities of retention modeling and computer assisted method development in supercritical fluid chromatography. (2015) (28)
SFC-MS versus RPLC-MS for drug analysis in biological samples. (2015) (27)
Lipophilicity Determination of Highly Lipophilic Compounds by Liquid Chromatography (2009) (27)
Evaluation of innovative stationary phase ligand chemistries and analytical conditions for the analysis of basic drugs by supercritical fluid chromatography. (2016) (27)
Implementation of a generic liquid chromatographic method development workflow: Application to the analysis of phytocannabinoids and Cannabis sativa extracts (2018) (27)
Validation of an ultra-fast UPLC-UV method for the separation of antituberculosis tablets. (2008) (27)
High resolution reversed phase analysis of recombinant monoclonal antibodies by ultra-high pressure liquid chromatography column coupling. (2013) (26)
From proof of concept to the routine use of an automated and robust multi-dimensional liquid chromatography mass spectrometry workflow applied for the charge variant characterization of therapeutic antibodies. (2019) (26)
Applicability of Supercritical fluid chromatography-Mass spectrometry to metabolomics. II-Assessment of a comprehensive library of metabolites and evaluation of biological matrices. (2020) (26)
Comparative study of recent wide-pore materials of different stationary phase morphology, applied for the reversed-phase analysis of recombinant monoclonal antibodies (2013) (26)
Analysis of antibody-drug conjugates by comprehensive on-line two-dimensional hydrophobic interaction chromatography x reversed phase liquid chromatography hyphenated to high resolution mass spectrometry. II- Identification of sub-units for the characterization of even and odd load drug species. (2016) (26)
Multi-dimensional LC-MS: the next generation characterization of antibody-based therapeutics by unified online bottom-up, middle-up and intact approaches. (2021) (26)
High-Throughput Screening of Drugs of Abuse in Urine by Supported Liquid–Liquid Extraction and UHPLC Coupled to Tandem MS (2009) (25)
Development of a fast workflow to screen the charge variants of therapeutic antibodies. (2017) (25)
Metamorphosis of supercritical fluid chromatography: A viable tool for the analysis of polar compounds? (2021) (25)
Streamlined characterization of an antibody-drug conjugate by two dimensional (2D) and four dimensional (4D) -LC/MS. (2019) (25)
Orthogonal Middle-up Approaches for Characterization of the Glycan Heterogeneity of Etanercept by Hydrophilic Interaction Chromatography Coupled to High-Resolution Mass Spectrometry. (2018) (25)
High‐resolution separation of monoclonal antibodies mixtures and their charge variants by an alternative and generic CZE method (2018) (25)
Use of individual retention modeling for gradient optimization in hydrophilic interaction chromatography: separation of nucleobases and nucleosides. (2014) (24)
Tuning selectivity in cation‐exchange chromatography applied for monoclonal antibody separations, part 1: Alternative mobile phases and fine tuning of the separation (2019) (24)
Coupling non-denaturing chromatography to mass spectrometry for the characterization of monoclonal antibodies and related products. (2020) (24)
Robust UHPLC Separation Method Development for Multi-API Product Containing Amlodipine and Bisoprolol: The Impact of Column Selection (2014) (23)
Optimized selection of liquid chromatography conditions for wide range analysis of natural compounds. (2017) (23)
A proof of concept to achieve infinite selectivity for the chromatographic separation of therapeutic proteins. (2019) (23)
Analysis of recombinant monoclonal antibodies in hydrophilic interaction chromatography: A generic method development approach (2017) (23)
Multi-target screening of biological samples using LC-MS/MS: focus on chromatographic innovations. (2014) (23)
Estimation of the effects of longitudinal temperature gradients caused by frictional heating on the solute retention using fully porous and superficially porous sub-2μm materials. (2014) (23)
Comprehensive study on the effects of sodium and potassium additives in size exclusion chromatographic separations of protein biopharmaceuticals (2017) (23)
The importance of system band broadening in modern size exclusion chromatography (2017) (22)
Fast and automated characterization of monoclonal antibody minor variants from cell cultures by combined Protein-A and multi-dimensional LC/MS methodologies. (2020) (22)
Optimization of non-linear gradient in hydrophobic interaction chromatography for the analytical characterization of antibody-drug conjugates. (2017) (22)
Development of a 3D-LC/MS workflow for fast, automated and effective characterization of glycosylation patterns of biotherapeutic products. (2020) (22)
New developments and possibilities of wide‐pore superficially porous particle technology applied for the liquid chromatographic analysis of therapeutic proteins (2018) (22)
Micro liquid chromatography coupled with evaporative light scattering detector at ambient and high temperature: optimization of the nebulization cell geometry. (2008) (22)
Quantification of 4 antidepressants and a metabolite by LC-MS for therapeutic drug monitoring. (2011) (22)
Predictive elution window stretching and shifting as a generic search strategy for automated method development for liquid chromatography. (2012) (22)
Some advantages of high temperature for the separation of pharmaceutical compounds with mass spectrometry detection. (2005) (21)
Separation of antibody drug conjugate species by RPLC: A generic method development approach (2017) (21)
Advances in LC platforms for drug discovery (2010) (21)
Determination of size variants by CE-SDS for approved therapeutic antibodies: Key implications of subclasses and light chain specificities. (2020) (20)
Chromatographic Performance of Silica-Based Stationary Phases in High Temperature Liquid Chromatography: Pharmaceutical Applications (2007) (20)
Protocols for the analytical characterization of therapeutic monoclonal antibodies. III - Denaturing chromatographic techniques hyphenated to mass spectrometry. (2018) (20)
Chromatographic Approaches for Measuring Log P (2007) (20)
Evolution and Current Trends in Liquid and Supercritical Fluid Chromatography (2014) (19)
Characterizing various monoclonal antibodies with milder reversed phase chromatography conditions. (2018) (19)
Achievable separation performance and analysis time in current liquid chromatographic practice for monoclonal antibody separations (2017) (19)
In vivo distribution and ex vivo permeation of cyclosporine A prodrug aqueous formulations for ocular application. (2013) (19)
A generic workflow for the characterization of therapeutic monoclonal antibodies—application to daratumumab (2019) (18)
Newer Developments in HPLC Impacting Pharmaceutical Analysis : A Brief Review (2013) (18)
Extending the limits of size exclusion chromatography: Simultaneous separation of free payloads and related species from antibody drug conjugates and their aggregates. (2018) (18)
Current and future trends in reversed-phase liquid chromatography-mass spectrometry of therapeutic proteins (2020) (18)
Separation of substrates and closely related glucuronide metabolites using various chromatographic modes. (2016) (18)
Natural compounds analysis using liquid and supercritical fluid chromatography hyphenated to mass spectrometry: Evaluation of a new design of atmospheric pressure ionization source. (2018) (17)
Reliability of computer-assisted method transfer between several column dimensions packed with 1.3-5μm core-shell particles and between various instruments. (2014) (17)
Use of Ultrashort Columns for Therapeutic Protein Separations. Part 1: Theoretical Considerations and Proof of Concept. (2020) (17)
Expanding the range of sub/supercritical fluid chromatography: Advantageous use of methanesulfonic acid in water-rich modifiers for peptide analysis. (2021) (16)
Composite resin vs resin cement for luting of indirect restorations: comparison of solubility and shrinkage behavior. (2013) (16)
Towards a simple on-line coupling of ion exchange chromatography and native mass spectrometry for the detailed characterization of monoclonal antibodies. (2021) (16)
Computer assisted liquid chromatographic method development for the separation of therapeutic proteins. (2016) (15)
A multi-target screening analysis in human plasma using fast liquid chromatography-hybrid tandem mass spectrometry (Part I). (2011) (14)
Advances in Hydrophilic Interaction Liquid Chromatography for Pharmaceutical Analysis (2013) (14)
An attempt to characterize the human Chorionic Gonadotropin protein by reversed phase liquid chromatography coupled with high‐resolution mass spectrometry at the intact level (2018) (14)
Evaluation of new superficially porous particles with carbon core and nanodiamond-polymer shell for proteins characterization. (2015) (13)
Supercritical fluid chromatography-mass spectrometry in routine anti-doping analyses: Estimation of retention time variability under reproducible conditions. (2019) (13)
Innovative methodology to transfer conventional GC-MS heroin profiling to UHPLC-MS/MS (2011) (13)
Negative gradient slope methods to improve the separation of closely eluting proteins. (2020) (13)
Evaluation of the coupling between ultra performance liquid chromatography and evaporative light scattering detector for selected phytochemical applications. (2008) (13)
A workflow for column interchangeability in liquid chromatography using modeling software and quality‐by‐design principles (2017) (13)
Evaluation of additives on reversed-phase chromatography of monoclonal antibodies using a 1000 Å stationary phase. (2020) (12)
Apparent efficiency of serially coupled columns in isocratic and gradient elution modes. (2018) (12)
Non-invasive targeted iontophoretic delivery of cetuximab to skin (2020) (12)
Preparative Scale MS-Guided Isolation of Bioactive Compounds Using High-Resolution Flash Chromatography: Antifungals from Chiloscyphus polyanthos as a Case Study (2016) (11)
Reversed-Phase Liquid Chromatography for the Analysis of Therapeutic Proteins and Recombinant Monoclonal Antibodies (2012) (11)
Ion mobility-high resolution mass spectrometry in anti-doping analysis. Part I: Implementation of a screening method with the assessment of a library of substances prohibited in sports. (2021) (11)
Tuning selectivity in cation-exchange chromatography applied for monoclonal antibody separations, part 2: Evaluation of recent stationary phases. (2019) (11)
State-of-the-Art Native Mass Spectrometry and Ion Mobility Methods to Monitor Homogeneous Site-Specific Antibody-Drug Conjugates Synthesis (2021) (11)
Is hydrophobic interaction chromatography the most suitable technique to characterize site-specific antibody-drug conjugates? (2019) (11)
Evaluation of a new wide-pore superficially porous material with carbon core and nanodiamond-polymer shell for the separation of proteins. (2015) (11)
Modern Column Technologies for the Analytical Characterization of Biopharmaceuticals in Various Liquid Chromatographic Modes (2015) (10)
Hyphenated Detectors: Mass Spectrometry (2017) (10)
Selection of suitable operating conditions to minimize the gradient equilibration time in the separation of drugs by Ultra-High-Pressure Liquid Chromatography with volatile (mass spectrometry-compatible) buffers. (2010) (10)
Comparison of various silica-based monoliths for the analysis of large biomolecules. (2013) (10)
On-tubing fluorescence measurements of the band broadening of contemporary injectors in ultra-high performance liquid chromatography. (2017) (10)
Inter-laboratory study to evaluate the performance of automated online characterization of antibody charge variants by multi-dimensional LC-MS/MS. (2021) (10)
Glycan-mediated technology for obtaining homogeneous site-specific conjugated antibody-drug conjugates: synthesis and analytical characterization by using complementary middle-up LC/HRMS analysis. (2020) (10)
Impact of particle size gradients on the apparent efficiency of chromatographic columns. (2019) (9)
Size Exclusion Chromatography of Protein Biopharmaceuticals: Past, Present and Future (2018) (9)
Use of Ultra-short Columns for Therapeutic Protein Separations, Part 2: Designing the Optimal Column Dimension for Reversed-Phase Liquid Chromatography. (2020) (9)
Improving selectivity and performing online on-column fractioning in liquid chromatography for the separation of therapeutic biopharmaceutical products. (2020) (9)
The importance of being metal-free: The critical choice of column hardware for size exclusion chromatography coupled to high resolution mass spectrometry. (2021) (9)
Targeted bottom-up characterization of recombinant monoclonal antibodies by multi-dimensional LC/MS. (2020) (9)
Automated middle-up approach for the characterization of biotherapeutic products by combining on-line hinge-specific digestion with RPLC-HRMS analysis. (2020) (9)
Development of a LC-MS/MS method for the determination of isomeric glutamyl peptides in food ingredients. (2018) (8)
Impact of the column on effluent pH in cation exchange pH gradient chromatography, a practical study. (2020) (8)
Prototype sphere-on-sphere silica particles for the separation of large biomolecules. (2016) (8)
Importance of vial shape and type on the reproducibility of size exclusion chromatography measurement of monoclonal antibodies. (2016) (8)
Alternative mobile phase additives for the characterization of protein biopharmaceuticals in liquid chromatography - Mass spectrometry. (2021) (8)
Ion mobility-high resolution mass spectrometry in doping control analysis. Part II: Comparison of acquisition modes with and without ion mobility. (2021) (8)
Enantiomeric methadone quantitation on real post-mortem dried matrix spots samples: Comparison of liquid chromatography and supercritical fluid chromatography coupled to mass spectrometry. (2021) (8)
Method Transfer Between Conventional HPLC and UHPLC (2012) (8)
Using 1.5 mm internal diameter columns for optimal compatibility with current liquid chromatographic systems. (2021) (7)
The impact of low adsorption surfaces for the analysis of DNA and RNA oligonucleotides. (2022) (7)
Evaluation of Different Tandem MS Acquisition Modes to Support Metabolite Annotation in Human Plasma Using Ultra High-Performance Liquid Chromatography High-Resolution Mass Spectrometry for Untargeted Metabolomics (2020) (7)
Interlaboratory study of a supercritical fluid chromatography method for the determination of pharmaceutical impurities: Evaluation of multi-systems reproducibility. (2021) (7)
Development of an innovative salt-mediated pH gradient cation exchange chromatography method for the characterization of therapeutic antibodies. (2020) (7)
New wide-pore superficially porous stationary phases with low hydrophobicity applied for the analysis of monoclonal antibodies. (2021) (6)
Ultra-short ion-exchange columns for fast charge variants analysis of therapeutic proteins. (2021) (6)
Investigating the use of unconventional temperatures in supercritical fluid chromatography. (2020) (6)
Influence of connection tubing in modern size exclusion chromatography and its impact on the characterization of mAbs (2018) (6)
Chapter 3:Method Transfer Between Conventional HPLC and UHPLC (2012) (5)
Robust UHPLC Separation Method Development for Multi-API Product Amlodipine and Bisoprolol : The Impact of Column Selection (2014) (5)
State-of-the art of (UHP)LC-MS(-MS) techniques and their practical application. (2013) (5)
Tips, Tricks, and Troubleshooting for Separations of Biomolecules, Part 1: Contemporary Reversed-Phase Protein Separations (2018) (5)
Automated ion exchange chromatography screening combined with in silico multifactorial simulation for efficient method development and purification of biopharmaceutical targets (2022) (5)
Apparent efficiency of serially coupled columns in gradient elution liquid chromatography: Extension to the combination of any column formats. (2019) (5)
Ultra‐high performance supercritical fluid chromatography coupled to tandem mass spectrometry for antidoping analyses: Assessment of the inter‐laboratory reproducibility with urine samples (2020) (4)
New trends in fast liquid chromatography (2007) (4)
Metabolite profiling of plant extracts by ultra-high pressure liquid chromatography at elevated temperature coupled to time-of-flight mass spectrometry (2009) (4)
Method Transfer in HPLC (2008) (4)
Pharmaceutical applications on columns packed with sub-2 microm particles. (2008) (4)
Alternative Strategies to Reversed-Phase Liquid Chromatography for the Analysis of Pharmaceutical Compounds (2017) (4)
Coupling UHPLC with MS : The Needs, Challenges, and Applications (2013) (4)
Bispecific antibody characterization by a combination of intact and site-specific/chain-specific LC/MS techniques. (2022) (4)
Theory and Practice of UHPLC and UHPLC-MS (2017) (4)
Optimization of MS-Compatible Mobile Phases for IEX Separation of Monoclonal Antibodies (2019) (4)
Trapping-Enrichment Multidimensional Liquid Chromatography with On-Line Deuterated Solvent Exchange for Streamlined Structure Elucidation at the Microgram Scale. (2022) (4)
Ultra-Fast Separations of Pharmaceutical Compounds with 10 mm Columns Packed with Sub-2 μm Particles (2008) (4)
Development of Rapid Analytical Methods in the Laboratory of Pharmaceutical Analytical Chemistry (LCAP) (2005) (3)
Combining the full potential of UHPSFC-QToF/MS and UHPLC-QToF/MS to improve the workflow efficiency of both plant metabolic profiling and natural bioactive discovery (2016) (3)
Improved separation by at-column dilution in preparative hydrophilic interaction chromatography. (2018) (3)
Computer-Assisted Method Development for Small and Large Molecules (2017) (3)
Direct coupling of size exclusion chromatography and mass spectrometry for the characterization of complex monoclonal antibody products (2022) (3)
Drug Loading and Distribution of ADCs After Reduction or IdeS Digestion and Reduction. (2020) (3)
Quantitative N-Glycan Profiling of Therapeutic Monoclonal Antibodies Performed by Middle-Up Level HILIC-HRMS Analysis (2021) (3)
New insights in pharmaceutical analysis. (2012) (2)
Rapid log P determination of natural products in crude plant extracts from UHPLC-TOF-MS profiling data – an additional parameter for dereplication and bioavailability (2009) (2)
Algorithms to optimize multi-column chromatographic separations of proteins. (2020) (2)
UHPLC, Part II: Benefits (2017) (2)
Practical considerations on the particle size and permeability of ion-exchange columns applied to biopharmaceutical separations. (2019) (2)
Isolation and Identification of Isocoumarin Derivatives With Specific Inhibitory Activity Against Wnt Pathway and Metabolome Characterization of Lasiodiplodia venezuelensis (2021) (2)
Theoretical and practical comparison of RPLC and RPLC × RPLC: how to consider dilution effects and sensitivity in addition to separation power? (2022) (2)
Fast Afucosylation Profiling of Glycoengineered Antibody Subunits by Middle-Up Mass Spectrometry. (2021) (2)
Aptamer-based immunoaffinity LC-MS using an ultra-short column for rapid attomole level quantitation of intact mAbs. (2021) (2)
Expediting the chromatographic analysis of COVID-19 antibody therapeutics with ultra-short columns, retention modeling and automated method development (2022) (1)
UHPLC Separations Using Sub-2 μm Particle Size Columns (2015) (1)
Boosting the Liquid Chromatography Separation of Complex Bispecific Antibody Products by Using the Multi-Isocratic Elution Mode (2022) (1)
Fast Optimization of Supercritical Fluid Chromatography-Mass Spectrometry Interfacing Using Prediction Equations. (2022) (1)
Characterization of antibody drug conjugates by an innovative on-line four-dimensional HICxSEC-IM-MS methodology (2018) (1)
Characterization of Glycosylated Proteins at Subunit Level by HILIC/MS. (2021) (1)
5. What is the potential of SFC-MS for doping control analysis? (2018) (1)
An online four-dimensional HICxSEC-IMxMS methodology for in-depth characterization of antibody drug conjugates (2017) (1)
Sub/supercritical fluid chromatography versus liquid chromatography for peptide analysis. (2022) (1)
Analytical challenges encountered and the potential of supercritical fluid chromatography: A perspective of five experts (2020) (1)
Development and application of a liquid chromatography coupled to mass spectrometry method for the simultaneous determination of 23 antineoplastic drugs at trace levels. (2022) (1)
Immortalized human myoblast cell lines for the delivery of therapeutic proteins using encapsulated cell technology (2022) (1)
Size Exclusion Chromatography Method Development for Therapeutic Proteins (2019) (1)
Potential of UHPLC for crude plant extract analysis: profiling, dereplication and metabolomics (2010) (1)
Anion-Exchange Chromatography at the Service of Gene Therapy: Baseline Separation of Full/Empty Adeno-Associated Virus Capsids by Screening of Conditions and Step Gradient Elution Mode (2022) (1)
Nouveaux développements en chromatographie rapide dans le domaine pharmaceutique (2009) (1)
Advantages and Applications of Revolutionary Superficially Porous Particle Columns in Liquid Chromatography (2013) (1)
Anticorps monoclonaux biosimilaires (2019) (1)
Interlaboratory Evaluation of a User-Friendly Benchtop Mass Spectrometer for Multiple-Attribute Monitoring Studies of a Monoclonal Antibody (2023) (1)
Monitoring multiple quality attributes of a complex Fc-fusion protein during cell culture production processes by mD-LC-MS peptide mapping. (2022) (1)
O22 The key role of analytical sciences in the discovery and characterization of bioactives from food and nutraceuticals (2017) (1)
Improving Selectivity in the Chromatographic Analysis of Monoclonal Antibodies (mAbs) Through the Use of Multi-Isocratic Elution Mode (2022) (1)
Comparative Study on Selectivity and Kinetic Performance of Recent Reversed Phase Liquid Chromatography Columns in the Separation of Protein Variants (2015) (1)
“HPLC Teaching Simulator”: A Simple Excel Tool for Teaching Liquid Chromatography (2018) (0)
Mass spectrometry guided purification for efficient isolation of natural products at semi- and preparative scale (2013) (0)
Transfer of heroin profiling method from conventional GC-MS to Fast-GC-MS and UHPLC-MS/MS (2009) (0)
Collaborative study of a Supercritical Fluid Chromatography method for the determination of pharmaceutical impurities (2018) (0)
Optimized MS-based isolation strategy for rapid targeted purification of antifungal compounds (2014) (0)
Detection apparatus for coupling a liquid chromatography column and equipped with means for the formation and transfer of aerosol (2006) (0)
[Biosimilar monoclonal antibodies: comparative study of analytical and functional quality]. (2019) (0)
Stratégies analytiques pour les contrôles antidopage : besoins, challenges et perspectives (2016) (0)
High-throughput screening of drugs of abuse in urine by supported liquid-liquid extraction and UHPLC coupled to tandem MS MAQUILLE , (2018) (0)
Tackling Issues Observed during the Development of a Liquid Chromatography Method for Small Molecule Quantification in Antibody-Chelator Conjugate (2023) (0)
Analytical Characterization of Biopharmaceuticals (2017) (0)
The use of SFC from research and development to quality control laboratories: dream or reality? (2018) (0)
Application of Different Chromatography and Mass Spectrometry Solutions to the Analysis of Fuels and Fuel Matrices (2017) (0)
Comprehensive on-line HICxRPLC-UV/MS for extensive characterization of cysteine-linked Antibody-Drug Conjugates (2016) (0)
Implementation of SFC for the quality control of pharmaceuticals (2017) (0)
Extending the performance of FcRn and FcγRIIIa affinity liquid chromatography for protein biopharmaceuticals. (2022) (0)
High Resolution Ion Mobility-ESI-MS for efficient profiling of natural products (2014) (0)
Automated Hydrophobic Interaction Chromatography Screening Combined with In Silico Optimization as a Framework for Nondenaturing Analysis and Purification of Biopharmaceuticals. (2022) (0)
Evaluation of thermally pretreated silica stationary phases under hydrophilic interaction chromatography conditions. (2016) (0)
Comprehensive evaluation of zwitterionic hydrophilic liquid chromatography stationary phases for oligonucleotide characterization. (2023) (0)
Abstract_eNews3_Nicolas Guichard (2017) (0)
Applying practical constraints to the kinetic plot representation of chromatographic performance data (2006) (0)
New findings in liquid chromatography in the pharmaceutical domain. (2011) (0)
Chromatographic Strategies for the Successful Characterization of Protein Biopharmaceuticals (2021) (0)
Evaluation of measurement uncertainty: from SFC method development to inter-laboratory study (2018) (0)
Characterization of charge variants for antibody-based biopharmaceuticals by mass spectrometry. (2019) (0)
HPLC Teaching Assistant: A New Tool for Learning and Teaching Liquid Chromatography, Part I (2016) (0)
THE RESULT OF 25 YEARS OF EVOLUTION (2014) (0)
Innovative strategies for the efficient isolation of natural at the preparative scale (2013) (0)
Highlights of Analytical Chemistry in Switzerland: Plant Metabolomics – Strategies for Biomarker Detection, Isolation, and Identification (2008) (0)
PharmaceuticalApplicationsonColumns PackedwithSub-2µmParticles (2008) (0)
Evaluation of Waters UPC 2 system and columns : application to compounds of pharmaceutical interest (2012) (0)
1 Monoclonal Antibody N-Glycosylation Profiling using 1 Capillary Electrophoresis – Mass Spectrometry : 2 Assessment and Method Validation . 3 (2019) (0)
Editorial for the special issue entitled "supercritical fluid chromatography - mass spectrometry". (2018) (0)
Évolutions majeures en chromatographie liquide (2014) (0)
Reversed HILIC Gradient: A Powerful Strategy for On-Line Comprehensive 2D-LC (2023) (0)
Editorial for the virtual special issue SEP 2019. (2020) (0)
Ultra-Fast Middle-Up Reversed Phase Liquid Chromatography Analysis of Complex Bispecific Antibodies Obtained in Less Than One Minute (2022) (0)
Editorial for the special issue titled "Biopharmaceuticals 2020". (2020) (0)
Empirical correction of non-linear pH gradients and a tool for application to protein ion exchange chromatography. (2021) (0)
Implementation of new Fast-GC-MS and UHPLC-MS/MS data in a conventional GC-MS database for heroin profiling (2009) (0)
Editorial for the special issue entitled "Biopharmaceuticals 2016". (2016) (0)
A New Practice to Monitor the Fabrication Process of Fab-Targeting Ligands from Bevacizumab by LC-MS: Preparation and Analytical Characterization (2022) (0)
Corrigendum to "Protocols for the analytical characterization of therapeutic monoclonal antibodies. I-Non-denaturing chromatographic techniques" [J. Chromatogr. B 1058 (2017) 73-84]. (2017) (0)
A simple mathematical treatment for predicting linear solvent strength behavior in gradient elution: Application to biomolecules (2022) (0)
Trapping‐Enrichment Multidimensional Liquid Chromatography with On‐Line Deuterated Solvent Exchange for Streamlined Structure Elucidation at the Microgram Scale (2022) (0)
Advanced technologies for exploring the chemical and functional properties of bioactive constituents in food (2016) (0)
Pressure–Enhanced Liquid Chromatography as a Suitable Approach to Improve Selectivity for Large Molecule Separations (2023) (0)
Corrigendum to “Retention modeling and method development in hydrophilic interaction chromatography” [J. Chromatogr. A 1337 (2014) 116–127] (2014) (0)
Quel est l’apport de la chromatographie en phase supercritique pour l’analyse antidopage ? (2018) (0)
Étude et utilisation de la chromatographie en phase liquide à haute température (2004) (0)
La chromatographie en phase supercritique : une alternative aux méthodes de référence de la Pharmacopée Européenne ? (2017) (0)
Description d'une méthode d'évaluation et de comparaison des performances chromatographiques (2008) (0)
Advances in Biopharmaceutical Analysis (2019) (0)
Investigation of several chromatographic approaches for untargeted profiling of central carbon metabolism. (2023) (0)

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What Schools Are Affiliated With Davy Guillarme?

Davy Guillarme is affiliated with the following schools:

Vrije Universiteit Brussel
University of Lausanne
University of Geneva