Debora Marks
#82,195
Most Influential Person Now
Computational biologist
Debora Marks's AcademicInfluence.com Rankings
Debora Marksbiology Degrees
Biology
#4100
World Rank
#6159
Historical Rank
Computational Biology
#109
World Rank
#109
Historical Rank
Bioinformatics
#138
World Rank
#140
Historical Rank
Debora Markscomputer-science Degrees
Computer Science
#10522
World Rank
#11055
Historical Rank
Informatics
#66
World Rank
#69
Historical Rank
Database
#7513
World Rank
#7790
Historical Rank
Download Badge
Biology Computer Science
Debora Marks's Degrees
- Masters Bioinformatics Stanford University
Why Is Debora Marks Influential?
(Suggest an Edit or Addition)According to Wikipedia, Debora S. Marks is a researcher in computational biology and a Professor of Systems Biology at Harvard Medical School. Her research uses computational approaches to address a variety of biological problems.
Debora Marks's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Human MicroRNA Targets (2004) (3683)
- MicroRNA targets in Drosophila (2003) (2606)
- The microRNA.org resource: targets and expression (2007) (2452)
- Identification of Virus-Encoded MicroRNAs (2004) (1628)
- Direct-coupling analysis of residue coevolution captures native contacts across many protein families (2011) (1155)
- Protein 3D Structure Computed from Evolutionary Sequence Variation (2011) (1010)
- The small RNA profile during Drosophila melanogaster development. (2003) (1002)
- miR-122, a Mammalian Liver-Specific microRNA, is Processed from hcr mRNA and MayDownregulate the High Affinity Cationic Amino Acid Transporter CAT-1 (2004) (766)
- Protein structure prediction from sequence variation (2012) (582)
- miRcode: a map of putative microRNA target sites in the long non-coding transcriptome (2012) (581)
- Transfection of small RNAs globally perturbs gene regulation by endogenous microRNAs (2009) (509)
- Three-Dimensional Structures of Membrane Proteins from Genomic Sequencing (2012) (504)
- MicroRNA profiling of the murine hematopoietic system (2005) (471)
- MicroRNA Targets in Drosophila (2003) (439)
- Sequence co-evolution gives 3D contacts and structures of protein complexes (2014) (431)
- Mutation effects predicted from sequence co-variation (2017) (350)
- The developmental miRNA profiles of zebrafish as determined by small RNA cloning. (2005) (343)
- Target mRNA abundance dilutes microRNA and siRNA activity (2010) (341)
- Antisense-Mediated Depletion Reveals Essential and Specific Functions of MicroRNAs in Drosophila Development (2005) (330)
- MicroRNA control of protein expression noise (2015) (327)
- Deep generative models of genetic variation capture the effects of mutations (2018) (302)
- Pathway and network analysis of cancer genomes (2015) (285)
- Quantification of the effect of mutations using a global probability model of natural sequence variation (2015) (238)
- Genomic Epidemiology of Gonococcal Resistance to Extended-Spectrum Cephalosporins, Macrolides, and Fluoroquinolones in the United States, 2000–2013 (2016) (172)
- FreeContact: fast and free software for protein contact prediction from residue co-evolution (2014) (149)
- Protein design and variant prediction using autoregressive generative models (2019) (139)
- Disease variant prediction with deep generative models of evolutionary data (2021) (137)
- 3D RNA and Functional Interactions from Evolutionary Couplings (2015) (137)
- Prediction of human microRNA targets. (2006) (133)
- Signatures of RNA binding proteins globally coupled to effective microRNA target sites. (2010) (132)
- A Systematic p53 Mutation Library Links Differential Functional Impact to Cancer Mutation Pattern and Evolutionary Conservation. (2018) (131)
- The EVcouplings Python framework for coevolutionary sequence analysis (2018) (130)
- Cryo–electron microscopy structure of the lipid droplet–formation protein seipin (2018) (128)
- Learning Protein Structure with a Differentiable Simulator (2018) (125)
- Corrigendum: Transfection of small RNAs globally perturbs gene regulation by endogenous microRNAs (2009) (123)
- Structured States of Disordered Proteins from Genomic Sequences (2016) (123)
- Amino acid coevolution reveals three-dimensional structure and functional domains of insect odorant receptors (2015) (115)
- PconsFold: improved contact predictions improve protein models (2014) (109)
- mRNA turnover rate limits siRNA and microRNA efficacy (2010) (103)
- Can sequencing shed light on cell cycling? (2001) (99)
- Inferring Pairwise Interactions from Biological Data Using Maximum-Entropy Probability Models (2015) (97)
- Correction: Human MicroRNA Targets (2005) (97)
- Inferring protein 3D structure from deep mutation scans (2019) (95)
- Computational Analysis of Mouse piRNA Sequence and Biogenesis (2007) (91)
- Off-target effects dominate a large-scale RNAi screen for modulators of the TGF-β pathway and reveal microRNA regulation of TGFBR2 (2011) (90)
- Genetic variation in human drug-related genes (2017) (85)
- Protein structure determination by combining sparse NMR data with evolutionary couplings (2015) (81)
- Structure of the peptidoglycan polymerase RodA resolved by evolutionary coupling analysis (2018) (80)
- Use of an additional hydrophobic binding site, the Z site, in the rational drug design of a new class of stronger trypanothione reductase inhibitor, quaternary alkylammonium phenothiazines (2000) (67)
- Structural coordination of polymerization and crosslinking by a SEDS-bPBP peptidoglycan synthase complex (2020) (61)
- Structure and Sequence Analyses of Clustered Protocadherins Reveal Antiparallel Interactions that Mediate Homophilic Specificity. (2015) (57)
- All-atom 3D structure prediction of transmembrane β-barrel proteins from sequences (2015) (54)
- Core Genes Evolve Rapidly in the Long-Term Evolution Experiment with Escherichia coli (2016) (54)
- CellBox: Interpretable Machine Learning for Perturbation Biology with Application to the Design of Cancer Combination Therapy. (2020) (51)
- Structure and mutagenic analysis of the lipid II flippase MurJ from Escherichia coli (2018) (43)
- Antiparallel protocadherin homodimers use distinct affinity- and specificity-mediating regions in cadherin repeats 1-4 (2016) (43)
- Large-scale discovery of protein interactions at residue resolution using co-evolution calculated from genomic sequences (2021) (41)
- Metaphyseal Chondrodysplasia Type Schmid Mutations Are Predicted to Occur in Two Distinct Three-dimensional Clusters within Type X Collagen NC1 Domains That Retain the Ability to Trimerize* (1999) (39)
- Accelerating Protein Design Using Autoregressive Generative Models (2019) (37)
- EVfold.org: Evolutionary Couplings and Protein 3D Structure Prediction (2015) (33)
- Variational Inference for Sparse and Undirected Models (2016) (32)
- Use of an additional hydrophobic binding site, the Z site, in the rational drug design of a new class of stronger trypanothione reductase inhibitor, quaternary alkylammonium phenothiazines. (2000) (31)
- A Systematic p53 Mutation Library Links Differential Functional Impact to Cancer Mutation Pattern and Evolutionary Conservation (2018) (31)
- Genome-wide discovery of epistatic loci affecting antibiotic resistance in Neisseria gonorrhoeae using evolutionary couplings (2018) (29)
- Rapid generation of potent antibodies by autonomous hypermutation in yeast (2021) (28)
- Tranception: protein fitness prediction with autoregressive transformers and inference-time retrieval (2022) (27)
- Regulated spatial organization and sensitivity of cytosolic protein oxidation in Caenorhabditis elegans (2014) (27)
- Multiplexed measurement of variant abundance and activity reveals VKOR topology, active site and human variant impact (2020) (24)
- PDBe-KB: collaboratively defining the biological context of structural data (2021) (22)
- Interaction specificity of clustered protocadherins inferred from sequence covariation and structural analysis (2018) (21)
- RITA: a Study on Scaling Up Generative Protein Sequence Models (2022) (20)
- Deep generative models of genetic variation capture mutation effects (2017) (19)
- Rapid generation of potent antibodies by autonomous hypermutation in yeast (2020) (19)
- Population-specific design of de-immunized protein biotherapeutics (2017) (16)
- A homology model of the three-dimensional structure of human O6-alkylguanine-DNA alkyltransferase based on the crystal structure of the C-terminal domain of the Ada protein from Escherichia coli. (1995) (15)
- Protein Structure from Experimental Evolution. (2019) (15)
- Structural studies by high-field NMR spectroscopy of a binary-addressed complementary oligonucleotide system juxtaposing pyrene and perfluoro-azide units. (1997) (14)
- Large-scale clinical interpretation of genetic variants using evolutionary data and deep learning (2020) (13)
- Noise control is a primary function of microRNAs and post-transcriptional regulation (2017) (13)
- 3D protein structure from genetic epistasis experiments (2018) (11)
- mRNA turnover rate limits siRNA and microRNA efficacy (2010) (11)
- Protein structure from experimental evolution (2019) (10)
- Structure, Dynamics and Implied Gating Mechanism of a Human Cyclic Nucleotide-Gated Channel (2014) (9)
- A Structured Observation Distribution for Generative Biological Sequence Prediction and Forecasting (2020) (9)
- Strong, Specific, Reversible Binding Ligands for Transfer RNA: Comparison by Fluoresence and NMR Spectroscopies with Distamycin Binding for a New Structural Class of Ligand (1998) (9)
- Pancreatic cancer risk predicted from disease trajectories using deep learning (2021) (9)
- Bayesian Sparsity for Intractable Distributions (2016) (9)
- Analysis working group of the International Cancer Genome Consortium (2015) (9)
- Cancer-associated recurrent mutations in RNase III domains of DICER1 (2014) (9)
- A similarity model for the human angiogenic factor, thymidine phosphorylase/platelet derived-endothelial cell growth factor. (1999) (9)
- Coevolution of interacting proteins through non-contacting and non-specific mutations (2021) (9)
- Gain‐of‐function experiments with bacteriophage lambda uncover residues under diversifying selection in nature (2018) (9)
- A Hybrid Approach for Protein Structure Determination Combining Sparse NMR with Evolutionary Coupling Sequence Data. (2018) (8)
- Refined high-field NMR solution structure of a binary-addressed pyrene/perfluoro-azide complementary DNA oligonucleotide system shows extensive distortion in the central nick region. (1999) (8)
- Dormant spores sense amino acids through the B subunits of their germination receptors (2021) (7)
- Combining Evolutionary Covariance and NMR Data for Protein Structure Determination. (2019) (7)
- Optimal Design of Stochastic DNA Synthesis Protocols based on Generative Sequence Models (2021) (7)
- Genome-wide discovery of epistatic loci affecting antibiotic resistance using evolutionary couplings (2018) (7)
- Evidence that regulation of intramembrane proteolysis is mediated by substrate gating during sporulation in Bacillus subtilis (2018) (7)
- Non-identifiability and the Blessings of Misspecification in Models of Molecular Fitness (2022) (7)
- Protein Structures, Interactions and Function from Evolutionary Couplings (2017) (6)
- Interpretable Machine Learning for Perturbation Biology (2019) (6)
- 3D Protein Structure Predicted from Sequence (2011) (5)
- Proteome-scale discovery of protein interactions with residue-level resolution using sequence coevolution (2019) (5)
- A generative nonparametric Bayesian model for whole genomes (2021) (5)
- The SpoVA membrane complex is required for dipicolinic acid import during sporulation and export during germination (2022) (5)
- An in silico method to assess antibody fragment polyreactivity (2022) (4)
- Learning from pre-pandemic data to forecast viral escape (2023) (4)
- scPerturb: Information Resource for Harmonized Single-Cell Perturbation Data (2022) (4)
- Natural and designed proteins inspired by extremotolerant organisms can form condensates and attenuate apoptosis in human cells (2021) (4)
- Mechanical gating of the auditory transduction channel TMC1 involves the fourth and sixth transmembrane helices (2022) (4)
- Estimation of Residue-Residue Coevolution using Direct Coupling Analysis Identifies Many Native Contacts Across a Large Number of Domain Families (2012) (3)
- Coordination of bacterial cell wall and outer membrane biosynthesis (2023) (3)
- MaveDB v2: a curated community database with over three million variant effects from multiplexed functional assays (2021) (3)
- Accurate prediction of transmembrane β-barrel proteins from sequences (2014) (3)
- scPerturb: Harmonized Single-Cell Perturbation Data (2023) (2)
- TranceptEVE: Combining Family-specific and Family-agnostic Models of Protein Sequences for Improved Fitness Prediction (2022) (2)
- The relaxin receptor RXFP1 signals through a mechanism of autoinhibition (2022) (2)
- Publisher Correction: Disease variant prediction with deep generative models of evolutionary data (2021) (2)
- Strong, Specific, Reversible Binding Ligands for Transfer RNA: Comparison by Fluorescence and NMR Spectroscopies with Distamycin Binding for a New Structural Class of Ligand. (1999) (2)
- High-content screening of coronavirus genes for innate immune suppression reveals enhanced potency of SARS-CoV-2 proteins (2021) (2)
- 3D RNA from evolutionary couplings (2015) (2)
- Generative models for codon prediction and optimization (2019) (2)
- Structure and function of the SEDS:bPBP bacterial cell wall synthesis machinery (2018) (2)
- Structural investigations of kirromycin bound to bacterial elongation factor Tu by NMR and molecular dynamics. (1997) (1)
- microRNA target sites Signatures of RNA binding proteins globally coupled to effective Material (2010) (1)
- Solutions to the computational protein folding problem (2018) (1)
- EC-NMR Structure of Arabidopsis thaliana At2g32350 Determined by Combining Evolutionary Couplings (EC) and Sparse NMR Data. Northeast Structural Genomics Consortium target AR3433A (2015) (0)
- EC-NMR Structure of Erwinia carotovora ECA1580 N-terminal Domain Determined by Combining Evolutionary Couplings (EC) and Sparse NMR Data. Northeast Structural Genomics Consortium target EwR156A (2015) (0)
- Using evolutionary couplings to predict contacts and build structures (2018) (0)
- Structural Investigation of a Binary-Addressed Oligonucleotide System Juxtaposing Pyrene and Perfluoroazide Units by means of High-Field NMR Spectroscopy and Molecular Modeling (1997) (0)
- small RNA cloning The developmental miRNA profiles of zebrafish as determined by Material Supplemental (2005) (0)
- Genetic variation in human drug-related genes you. (2017) (0)
- Viral gain-of-function experiments uncover residues under diversifying selection in nature (2018) (0)
- Mapping the determinants of substrate selectivity in a bacterial metal transporter with model-guided deep mutagenesis (2023) (0)
- EC-NMR Structure of Ralstonia metallidurans Rmet_5065 Determined by Combining Evolutionary Couplings (EC) and Sparse NMR Data. Northeast Structural Genomics Consortium target CrR115 (2015) (0)
- Evolutionary Couplings Reveal Alternative 3D Structures (2018) (0)
- Genetic variation in human drug-related genes (2017) (0)
- Structure of mouse clustered PcdhgA1 EC1-3 (2015) (0)
- EC-NMR Structure of Agrobacterium tumefaciens Atu1203 Determined by Combining Evolutionary Couplings (EC) and Sparse NMR Data. Northeast Structural Genomics Consortium target AtT10 (2015) (0)
- Abstract LB550: AI predicts risk of pancreatic cancer from disease trajectories using real-world electronic health records (EHRs) from Denmark and the USA (2022) (0)
- High content screening and computational prediction reveal viral genes that suppress innate immune response (2021) (0)
- Potential miRNA Target Sites in the 3′ UTRs of Selected Genes (2013) (0)
- EVcomplex Supplementary Data (2014) (0)
- Saturation and competition drive siRNA and microRNA activity: It's more than the binding sites (2010) (0)
- Crystal structure of Thermus thermophilus Rod shape determining protein RodA (Q5SIX3_THET8) (2018) (0)
- Supplementary text: Direct-coupling analysis of residue co-evolution captures native contacts across many protein families (2011) (0)
- Combining Evolutionary Co-variance and NMR Data for Protein Structure Determination (2019) (0)
- Structural coordination of polymerization and crosslinking by a SEDS–bPBP peptidoglycan synthase complex (2020) (0)
- Abstract 2102: Interpretable machine learning for perturbation biology (2020) (0)
- EC-NMR Structure of Escherichia coli YiaD Determined by Combining Evolutionary Couplings (EC) and Sparse NMR Data. Northeast Structural Genomics Consortium target ER553 (2015) (0)
- Biological Sequence Kernels with Guaranteed Flexibility (2023) (0)
- RNA from evolutionary couplings (2015) (0)
- Inferring protein 3D structure from deep mutation scans (2019) (0)
- Genome-wide discovery of epistatic loci affecting antibiotic resistance in Neisseria gonorrhoeae using evolutionary couplings (2018) (0)
- EC-NMR Structure of Human H-RasT35S mutant protein Determined by Combining Evolutionary Couplings (EC) and Sparse NMR Data (2015) (0)
- A systematic p53 mutation library links functional impact to evolutionary conservation and cancer mutation pattern (2017) (0)
- EC-NMR Structure of Escherichia coli Maltose-binding protein Determined by Combining Evolutionary Couplings (EC) and Sparse NMR Data with a second set of RDC data simulated for an alternative alignment tensor. Northeast Structural Genomics Consortium target ER690 (2015) (0)
- EC-NMR Structure of Synechocystis sp. PCC 6803 Slr1183 Determined by Combining Evolutionary Couplings (EC) and Sparse NMR Data. Northeast Structural Genomics Consortium target SgR145 (2015) (0)
- Deep generative models of genetic variation capture the effects of mutations (2018) (0)
- High-Content Screening and Computational Prediction Reveal Viral Genes That Suppress the Innate Immune Response (2022) (0)
- MicroRNAs Reduce Gene Expression Noise (2014) (0)
- A Systematic p 53 Mutation Library Links Differential Functional Impact to Cancer Mutation Pattern and Evolutionary Conservation Highlights (0)
- Variational Inference for Sparse and Undirected Models : Appendix (2017) (0)
- Viral Evolution and Antibody Escape Mutations using Deep Generative Models (2021) (0)
- Generative probabilistic biological sequence models that account for mutational variability (2020) (0)
- EC-NMR Structure of Escherichia coli Maltose-binding protein Determined by Combining Evolutionary Couplings (EC) and Sparse NMR Data. Northeast Structural Genomics Consortium target ER690 (2015) (0)
- Democratizing the mapping of gene mutations to protein biophysics (2022) (0)
- Sequence network 1 D 2 D Structure network Invariant features A C OrientationsDistances B weights features Energy (2019) (0)
This paper list is powered by the following services:
Other Resources About Debora Marks
What Schools Are Affiliated With Debora Marks?
Debora Marks is affiliated with the following schools:
