Deborah Ashby
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Deborah Ashby's Degrees
- Bachelors Mathematics University of Nottingham
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(Suggest an Edit or Addition)According to Wikipedia, Deborah Ashby is a British statistician and academic who specialises in medical statistics and Bayesian statistics. She is the Director of the School of Public Health and Chair in Medical Statistics and Clinical Trials at Imperial College London. She was previously a lecturer then a reader at the University of Liverpool and a professor at Queen Mary University of London.
Deborah Ashby's Published Works
Published Works
- Effects of targeted delivery of propionate to the human colon on appetite regulation, body weight maintenance and adiposity in overweight adults (2014) (837)
- Genetic Loci associated with C-reactive protein levels and risk of coronary heart disease. (2009) (614)
- Variations in primary open-angle glaucoma prevalence by age, gender, and race: a Bayesian meta-analysis. (2006) (445)
- Sample size for cluster randomized trials: effect of coefficient of variation of cluster size and analysis method. (2006) (422)
- Effect of Early Vasopressin vs Norepinephrine on Kidney Failure in Patients With Septic Shock: The VANISH Randomized Clinical Trial. (2016) (387)
- Prospective observational single-centre cohort study to evaluate the effectiveness of treating lupus nephritis with rituximab and mycophenolate mofetil but no oral steroids (2013) (379)
- Selective serotonin reuptake inhibitors (SSRIs) and suicide in adults: meta-analysis of drug company data from placebo controlled, randomised controlled trials submitted to the MHRA's safety review (2005) (377)
- Repeated nebulisation of non-viral CFTR gene therapy in patients with cystic fibrosis: a randomised, double-blind, placebo-controlled, phase 2b trial (2015) (353)
- Social Science and the Evidence-based Policy Movement (2002) (282)
- Antidepressant treatment and the risk of fatal and non-fatal self harm in first episode depression: nested case-control study (2005) (258)
- Lessons for cluster randomized trials in the twenty-first century: a systematic review of trials in primary care (2004) (257)
- Levosimendan for the Prevention of Acute Organ Dysfunction in Sepsis. (2016) (228)
- Chronic musculoskeletal pain rarely presents in a single body site: results from a UK population study. (2007) (225)
- Iron deficiency and raised hepcidin in idiopathic pulmonary arterial hypertension: clinical prevalence, outcomes, and mechanistic insights. (2011) (220)
- Bayesian statistics in medicine: a 25 year review (2006) (216)
- Internal and external validity of cluster randomised trials: systematic review of recent trials (2008) (202)
- Erythropoietin administration in humans causes a marked and prolonged reduction in circulating hepcidin (2010) (190)
- Fibrosing colonopathy in cystic fibrosis: results of a case-control study (1995) (188)
- Orthodontic treatment for posterior crossbites. (2014) (184)
- Antibody prevalence for SARS-CoV-2 in England following first peak of the pandemic: REACT2 study in 100,000 adults (2020) (168)
- Epidemiology of COVID-19 in an Urban Dialysis Center. (2020) (166)
- Psychiatric illness in residential homes for the elderly: a survey in one London borough. (1984) (160)
- Metformin Does Not Affect Cancer Risk: A Cohort Study in the U.K. Clinical Practice Research Datalink Analyzed Like an Intention-to-Treat Trial (2014) (158)
- Antidepressants and suicide: what is the balance of benefit and harm (2004) (148)
- Blood lipids in middle-aged British men. (1983) (147)
- SARS-CoV-2 antibody prevalence in England following the first peak of the pandemic (2021) (139)
- Transcriptomic Signatures in Sepsis and a Differential Response to Steroids. From the VANISH Randomized Trial (2019) (135)
- Declining prevalence of antibody positivity to SARS-CoV-2: a community study of 365,000 adults (2020) (135)
- Diurnal variations in serum biochemical and haematological measurements. (1989) (134)
- Changes in physiological, functional and structural markers of cystic fibrosis lung disease with treatment of a pulmonary exacerbation (2013) (131)
- Evidence-based medicine as Bayesian decision-making. (2000) (127)
- Sustained appetite improvement in malnourished dialysis patients by daily ghrelin treatment. (2009) (126)
- Smooth muscle cholinergic denervation hypersensitivity in diverticular disease (2003) (124)
- Discussion on the paper by Spiegelhalter, Sherlaw-Johnson, Bardsley, Blunt, Wood and Grigg (2012) (119)
- Biochemical and Haematological Response to Alcohol Intake (1985) (119)
- Kisspeptin-54 triggers egg maturation in women undergoing in vitro fertilization. (2014) (119)
- Emergency department treatments and physiotherapy for acute whiplash: a pragmatic, two-step, randomised controlled trial (2013) (116)
- A prospective randomised controlled trial comparing the efficacy of somatostatin with injection sclerotherapy in the control of bleeding oesophageal varices. (1992) (114)
- Plasma hepcidin levels are elevated but responsive to erythropoietin therapy in renal disease. (2009) (113)
- Rituximab versus cyclophosphamide for the treatment of connective tissue disease-associated interstitial lung disease (RECITAL): study protocol for a randomised controlled trial (2017) (112)
- The relationship between blood lead, blood pressure, stroke, and heart attacks in middle-aged British men. (1988) (110)
- Efficacy of Kisspeptin-54 to Trigger Oocyte Maturation in Women at High Risk of Ovarian Hyperstimulation Syndrome (OHSS) During In Vitro Fertilization (IVF) Therapy (2015) (110)
- DELTA2 guidance on choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial (2018) (110)
- Tutorial in biostatistics Bayesian data monitoring in clinical trials. (1997) (110)
- Advice to use topical or oral ibuprofen for chronic knee pain in older people: randomised controlled trial and patient preference study (2007) (109)
- Blood lead concentration, blood pressure, and renal function. (1984) (108)
- Clinical and laboratory evaluation of SARS-CoV-2 lateral flow assays for use in a national COVID-19 seroprevalence survey (2020) (105)
- A systematic review of chronic fatigue, its syndromes and ethnicity: prevalence, severity, co-morbidity and coping. (2009) (105)
- The Interaction of Vasopressin and Corticosteroids in Septic Shock: A Pilot Randomized Controlled Trial* (2014) (104)
- Where errors occur in the preparation and administration of intravenous medicines: a systematic review and Bayesian analysis (2010) (103)
- Dynamic correlation of apoptosis and immune activation during treatment of HIV infection (1999) (103)
- Survival of very preterm infants admitted to neonatal care in England 2008–2014: time trends and regional variation (2017) (102)
- Effectiveness of financial incentives to improve adherence to maintenance treatment with antipsychotics: cluster randomised controlled trial (2013) (100)
- Balancing benefit and risk of medicines: a systematic review and classification of available methodologies (2014) (97)
- Respiratory syncytial virus bronchiolitis: Disease severity, interleukin‐8, and virus genotype * (2002) (91)
- Tuberculin testing in residential homes for the elderly. (1993) (85)
- High prevalence but low impact of data extraction and reporting errors were found in Cochrane systematic reviews. (2005) (84)
- Report of the CSM Expert Working Group on the Safety of Selective Serotonin Reuptake Inhibitor Antidepressants (2005) (84)
- Practical statistics for medical research. Douglas G. Altman, Chapman and Hall, London, 1991. No. of pages: 611. Price: £32.00 (1991) (83)
- Exponential growth, high prevalence of SARS-CoV-2, and vaccine effectiveness associated with the Delta variant (2021) (82)
- REal-time Assessment of Community Transmission (REACT) of SARS-CoV-2 virus: Study protocol. (2020) (79)
- Informed patient consent to participation in cluster randomized trials: an empirical exploration of trials in primary care (2005) (77)
- Lead exposure and children's intellectual performance. (1987) (77)
- Resurgence of SARS-CoV-2: Detection by community viral surveillance (2021) (76)
- Rapid increase in Omicron infections in England during December 2021: REACT-1 study (2021) (75)
- Development of a novel immunoassay for the iron regulatory peptide hepcidin (2009) (72)
- A Systematic Review of Pain Drawing Literature: Should Pain Drawings Be Used for Psychologic Screening? (2006) (71)
- Renal Association Clinical Practice Guideline on Haemodialysis (2019) (70)
- Oral protein energy supplements for children with cystic fibrosis: CALICO multicentre randomised controlled trial (2006) (70)
- The cardiopulmonary effects of vasopressin compared with norepinephrine in septic shock. (2012) (69)
- Oral steroids for cystic fibrosis. (1999) (69)
- Psychiatric illness in elderly residents of Part III homes in one London Borough: prognosis and review. (1988) (66)
- Nutritional Evaluation and Optimisation in Neonates: a randomized, double-blind controlled trial of amino acid regimen and intravenous lipid composition in preterm parenteral nutrition12 (2016) (65)
- High energy neutron treatment for pelvic cancers: study stopped because of increased mortality. (1991) (65)
- Azithromycin for Acute Exacerbations of Asthma : The AZALEA Randomized Clinical Trial. (2016) (65)
- DELTA2 guidance on choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial (2018) (64)
- Cardiac survival after pre-emptive coronary angiography in transplant patients and those awaiting transplantation. (2011) (64)
- Orthodontic treatment for posterior crossbites. (2001) (64)
- Diet and colorectal cancer: an investigation of the lectin/galactose hypothesis. (2002) (63)
- Topical or oral ibuprofen for chronic knee pain in older people. The TOIB study. (2008) (63)
- Vasopressin in septic shock: an individual patient data meta-analysis of randomised controlled trials (2019) (61)
- Population antibody responses following COVID-19 vaccination in 212,102 individuals (2022) (61)
- Prevalence of antibody positivity to SARS-CoV-2 following the first peak of infection in England: Serial cross-sectional studies of 365,000 adults (2021) (60)
- Ursodeoxycholic acid for cystic fibrosis-related liver disease. (2012) (59)
- Progressive human immunodeficiency virus-specific immune recovery with prolonged viral suppression. (2001) (57)
- Patient‐reported outcomes in the ProtecT randomized trial of clinically localized prostate cancer treatments: study design, and baseline urinary, bowel and sexual function and quality of life (2016) (56)
- Community prevalence of SARS-CoV-2 virus in England during May 2020: REACT study (2020) (56)
- Ursodeoxycholic acid for cystic fibrosis-related liver disease. (2017) (56)
- Bacteremia associated with tunneled hemodialysis catheters: outcome after attempted salvage. (2009) (55)
- Randomized controlled trials in cystic fibrosis (1966–1997) categorized by time, design, and intervention (2000) (53)
- DELTA 2 guidance on choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial (2018) (52)
- Recommendations for benefit–risk assessment methodologies and visual representations (2016) (52)
- Reduction in Exposure to Lead from Drinking Water and its Effect on Blood Lead Concentrations (1984) (51)
- A multitude of syntheses: a comparison of five approaches from diverse policy fields (2006) (51)
- Translumbar central venous catheters for long-term haemodialysis. (2010) (49)
- Respiratory syncytial virus genotypes and disease severity among children in hospital (1997) (47)
- Twin peaks: The Omicron SARS-CoV-2 BA.1 and BA.2 epidemics in England (2022) (47)
- Cytokines in severe respiratory syncytial virus bronchiolitis (2002) (46)
- Long-term outcome in biopsy-proven acute interstitial nephritis treated with steroids (2016) (45)
- Blood Cadmium Concentrations in the General Population of British Middle-aged Men (1988) (45)
- An investigation of the effects on children of tooth extraction under general anaesthesia in general dental practice. (1999) (43)
- Time to publication as full reports of abstracts of randomized controlled trials in cystic fibrosis (1998) (43)
- REACT-1 round 12 report: resurgence of SARS-CoV-2 infections in England associated with increased frequency of the Delta variant (2021) (43)
- SARS-CoV-2 lateral flow assays for possible use in national covid-19 seroprevalence surveys (React 2): diagnostic accuracy study (2021) (42)
- The adaptive designs CONSORT extension (ACE) statement: a checklist with explanation and elaboration guideline for reporting randomised trials that use an adaptive design (2019) (41)
- Supplementation of iron in pulmonary hypertension: Rationale and design of a phase II clinical trial in idiopathic pulmonary arterial hypertension (2013) (41)
- REACT-2 Round 5: increasing prevalence of SARS-CoV-2 antibodies demonstrate impact of the second wave and of vaccine roll-out in England (2021) (40)
- Oral steroids for long-term use in cystic fibrosis. (2011) (40)
- Structured Frameworks to Increase the Transparency of the Assessment of Benefits and Risks of Medicines: Current Status and Possible Future Directions (2015) (40)
- Exponential growth, high prevalence of SARS-CoV-2 and vaccine effectiveness associated with Delta variant in England during May to July 2021 (2021) (40)
- An efficacy and mechanism evaluation study of Levosimendan for the Prevention of Acute oRgan Dysfunction in Sepsis (LeoPARDS): protocol for a randomized controlled trial (2014) (39)
- Oral steroids for long-term use in cystic fibrosis. (2015) (38)
- Blood pressure and hypertension in middle-aged British men. (1988) (37)
- Chronic fatigue syndrome in an ethnically diverse population: the influence of psychosocial adversity and physical inactivity (2011) (37)
- Financial incentives to improve adherence to anti-psychotic maintenance medication in non-adherent patients - a cluster randomised controlled trial (FIAT) (2009) (36)
- Hydroxycloroquine blood concentration in lupus nephritis: a determinant of disease outcome? (2017) (36)
- Simple Bayesian Analyses for Case‐Control Studies in Cancer Epidemiology (1993) (36)
- Psychiatric morbidity as predictor of mortality for residents of local authority homes for the elderly (1991) (36)
- paediatric dentistry: An investigation of the effects on children of tooth extraction under general anaesthesia in general dental practice (1999) (35)
- Managing Injuries of the Neck Trial (MINT): a randomised controlled trial of treatments for whiplash injuries. (2012) (35)
- The ordered logistic regression model in psychiatry: rising prevalence of dementia in old people's homes. (1989) (35)
- Is it exposure to cigarette smoke or to smokers which increases the risk of meningococcal disease in teenagers? (2006) (35)
- A brief sensitive screening instrument for depression in late life. (1994) (34)
- An Analysis of Papers Published in the British and European Journals of Orthodontics (1996) (34)
- Central Venous Stenosis, Access Outcome and Survival in Patients undergoing Maintenance Hemodialysis. (2019) (34)
- Adjusting for publication bias: modelling the selection process. (2004) (34)
- Reliability of percentage ideal weight for height (2000) (34)
- Pharmacokinetics, adverse effects and tolerability of a novel analogue of human pancreatic polypeptide, PP 1420. (2012) (33)
- Usability and acceptability of home-based self-testing for SARS-CoV-2 antibodies for population surveillance. (2020) (33)
- Simple Bayesian analysis in clinical trials: a tutorial. (1994) (32)
- Inadvertent postdialysis anticoagulation due to heparin line locks (2007) (32)
- The demographic characteristics of pregnant women infected with cytomegalovirus. (1985) (32)
- Systematic reviews and lifelong diseases (2002) (32)
- An introduction to statistical methods for health technology assessment. (2000) (31)
- Hepcidin-25 in Diabetic Chronic Kidney Disease Is Predictive for Mortality and Progression to End Stage Renal Disease (2015) (31)
- Managing Injuries of the Neck Trial (MINT): design of a randomised controlled trial of treatments for whiplash associated disorders (2007) (28)
- Cardiovascular MRI in clinical trials: expanded applications through novel surrogate endpoints (2011) (28)
- Consensus and controversy in pharmaceutical statistics - Discussion (2000) (27)
- High but stable incidence of subdural haematoma in haemodialysis--a single-centre study. (2010) (27)
- Environmental lead and children's intelligence: a review of recent epidemiological studies (1985) (27)
- Usability and Acceptability of Home-based Self-testing for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Antibodies for Population Surveillance (2020) (26)
- Recent progress in PYY research—An update report for 8th NPY meeting (2007) (26)
- Bayesian data monitoring in clinical trials (1997) (26)
- Attenuated Salmonella typhimurium SL3261 as a vaccine vector for recombinant antigen in rabbits. (2005) (25)
- Protocol for a randomised controlled trial of VAsopressin versus Noradrenaline as Initial therapy in Septic sHock (VANISH) (2014) (25)
- REACT-1 round 7 updated report: regional heterogeneity in changes in prevalence of SARS-CoV-2 infection during the second national COVID-19 lockdown in England (2020) (24)
- High prevalence of SARS-CoV-2 swab positivity and increasing R number in England during October 2020: REACT-1 round 6 interim report (2020) (24)
- A randomised, double-blind, placebo-controlled trial of repeated nebulisation of non-viral cystic fibrosis transmembrane conductance regulator ( CFTR) gene therapy in patients with cystic fibrosis (2016) (23)
- A Bayesian approach to probabilistic sensitivity analysis in structured benefit‐risk assessment (2016) (23)
- Literature review of visual representation of the results of benefit–risk assessments of medicinal products (2016) (22)
- Benefit–risk assessment in a post‐market setting: a case study integrating real‐life experience into benefit–risk methodology (2014) (22)
- Risk of COVID-19 Disease, Dialysis Unit Attributes, and Infection Control Strategy among London In-Center Hemodialysis Patients (2021) (22)
- IMI-PROTECT benefit-risk grouprecommendations report:recommendations for the methodology andvisualisation techniques to be used in theassessment of benefit and risk of medicines (2014) (22)
- Intravenous versus oral antibiotics for eradication of Pseudomonas aeruginosa in cystic fibrosis (TORPEDO-CF): a randomised controlled trial (2020) (21)
- Levosimendan in septic shock in patients with biochemical evidence of cardiac dysfunction: a subgroup analysis of the LeoPARDS randomised trial (2019) (21)
- Progression of whole-blood transcriptional signatures from interferon-induced to neutrophil-associated patterns in severe influenza (2018) (21)
- Informing the Risk of Kidney Transplantation Versus Remaining on the Waitlist in the Coronavirus Disease 2019 Era (2020) (20)
- The prescription of psychotropic medication in local authority old people's homes (1986) (20)
- Resurgence of SARS-CoV-2 in England: detection by community antigen surveillance (2020) (19)
- Cumulative flying time and risk of venous thromboembolism (2011) (19)
- Increased incidence of anti-glomerular basement membrane antibody (anti-GBM) nephritis in the Mersey Region, September 1984-October 1985. (1988) (19)
- Ursodeoxycholic acid for cystic fibrosis-related liver disease. (2017) (19)
- SARS-CoV-2 infection and vaccine effectiveness in England (REACT-1): a series of cross-sectional random community surveys (2022) (18)
- Ten-year patient survival on maintenance haemodialysis: association with treatment time and dialysis dose. (2013) (18)
- Long-term Tesio catheter access for hemodialysis can deliver high dialysis adequacy with low complication rates. (2011) (18)
- Prokinetics Prescribing in Paediatrics: Evidence on Cisapride, Domperidone, and Metoclopramide (2015) (18)
- Rituximab versus intravenous cyclophosphamide in patients with connective tissue disease-associated interstitial lung disease in the UK (RECITAL): a double-blind, double-dummy, randomised, controlled, phase 2b trial. (2022) (17)
- Long-Term Trends in Biochemical Data Obtained from Two Population Surveys (1986) (17)
- Thrombosis prevention trial: compliance with warfarin treatment and investigation of a retained effect. (2003) (17)
- Severity of COVID-19 after Vaccination among Hemodialysis Patients (2022) (16)
- Lack of effect of influenza immunisation on anticoagulant control in patients on long‐term warfarin (2007) (16)
- REACT-1 round 6 updated report: high prevalence of SARS-CoV-2 swab positivity with reduced rate of growth in England at the start of November 2020 (2020) (16)
- Cohort Study of Outpatient Hemodialysis Management Strategies for COVID-19 in North-West London (2020) (16)
- FOR DEBATE: IS THE EVIDENCE FOR THE EFFICACY OF CHOLINESTERASE INHIBITORS IN THE SYMPTOMATIC TREATMENT OF ALZHEIMER'S DISEASE CONVINCING OR NOT? (2008) (16)
- A Bayesian approach to complex clinical diagnoses: a case‐study in child abuse (2013) (15)
- Review of visualisation methods for therepresentation of benefit-risk assessment ofmedication: stage 2 of 2 (2013) (15)
- DOES HLA‐DR PREDICT RESPONSE TO SPECIFIC IMMUNOSUPPRESSIVE THERAPY IN APLASTIC ANAEMIA? (1990) (15)
- Author Correction: Progression of whole-blood transcriptional signatures from interferon-induced to neutrophil-associated patterns in severe influenza (2019) (15)
- High prevalence of SARS-CoV-2 swab positivity in England during September 2020: interim report of round 5 of REACT-1 study (2020) (14)
- Developing routinely recorded clinical data from electronic patient records as a national resource to improve neonatal health care: the Medicines for Neonates research programme (2019) (14)
- Taste preference for oral calorie supplements in children with cystic fibrosis, healthy children and healthy adults (1999) (13)
- Increased prevalence of eosinophilia in a hemodialysis population: Longitudinal and case control studies (2016) (13)
- Gut hormones and the treatment of disease cachexia (2008) (13)
- Post-peak dynamics of a national Omicron SARS-CoV-2 epidemic during January 2022 (2022) (13)
- REACT-1 round 8 final report: high average prevalence with regional heterogeneity of trends in SARS-CoV-2 infection in the community in England during January 2021 (2021) (13)
- REACT-1 study round 14: High and increasing prevalence of SARS-CoV-2 infection among school-aged children during September 2021 and vaccine effectiveness against infection in England (2021) (13)
- TOIB Study. Are topical or oral ibuprofen equally effective for the treatment of chronic knee pain presenting in primary care: a randomised controlled trial with patient preference study. [ISRCTN79353052] (2005) (13)
- Republished paper: Where errors occur in the preparation and administration of intravenous medicines: a systematic review and Bayesian analysis (2010) (13)
- Where's the utility in Bayesian data-monitoring of clinical trials? (2005) (13)
- Dynamics of competing SARS-CoV-2 variants during the Omicron epidemic in England (2022) (12)
- Transient dynamics of SARS-CoV-2 as England exited national lockdown (2020) (12)
- High and increasing prevalence of SARS-CoV-2 swab positivity in England during end September beginning October 2020: REACT-1 round 5 updated report (2020) (12)
- Using disease registries for pharmacoepidemiological research: a case study of data from a cystic fibrosis registry (2003) (12)
- Suicidal behaviour and SSRIs: updated meta-analysis (2006) (12)
- REACT-1 round 9 final report: Continued but slowing decline of prevalence of SARS-CoV-2 during national lockdown in England in February 2021 (2021) (12)
- Practical help for specifying the target difference in sample size calculations for RCTs: the DELTA2 five-stage study, including a workshop. (2019) (12)
- REACT-1 round 7 interim report: fall in prevalence of swab-positivity in England during national lockdown (2020) (11)
- REal-time Assessment of Community Transmission (REACT) of SARS-CoV-2 virus: Study protocol (2021) (11)
- Haemodialysis: hospital or home? (2013) (11)
- Ursodeoxycholic Acid in Cystic Fibrosis-Related Liver Disease: A Systematic Review (1997) (11)
- Vaccine uptake and SARS-CoV-2 antibody prevalence among 207,337 adults during May 2021 in England: REACT-2 study (2021) (11)
- REACT-1 round 13 interim report: acceleration of SARS-CoV-2 Delta epidemic in the community in England during late June and early July 2021 (2021) (11)
- SARS-CoV-2 lineage dynamics in England from September to November 2021: high diversity of Delta sub-lineages and increased transmissibility of AY.4.2 (2021) (11)
- REACT-1 round 9 interim report: downward trend of SARS-CoV-2 in England inFebruary 2021 but still at high prevalence (2021) (10)
- REACT-1 round 8 interim report: SARS-CoV-2 prevalence during the initial stages of the third national lockdown in England (2021) (10)
- Ursodeoxycholic acid for cystic fibrosis-related liver disease. (2014) (10)
- Kisspeptin: a novel physiological trigger for oocyte maturation in in-vitro fertilisation treatment (2014) (10)
- Appropriately smoothing prevalence data to inform estimates of growth rate and reproduction number (2022) (10)
- Stopping rules, interim analyses and data monitoring committees. (1993) (9)
- SARS-CoV-2 lineage dynamics in England from January to March 2021 inferred from representative community samples (2021) (9)
- Developing a Bayesian adaptive design for a phase I clinical trial: a case study for a novel HIV treatment (2016) (9)
- Dynamics of a national Omicron SARS-CoV-2 epidemic during January 2022 in England (2022) (9)
- REACT-1 round 15 final report: Increased breakthrough SARS-CoV-2 infections among adults who had received two doses of vaccine, but booster doses and first doses in children are providing important protection (2021) (8)
- Weighing benefit-risk of medicines: concepts and approaches. (2011) (8)
- Nutritional Evaluation and Optimisation in Neonates (NEON) trial of amino acid regimen and intravenous lipid composition in preterm parenteral nutrition: a randomised double-blind controlled trial (2016) (8)
- Data Authorship as an Incentive to Data Sharing. (2017) (8)
- Hepcidin--a well-known iron biomarker with prognostic implications in chronic kidney disease. (2013) (8)
- A first-in-human study of the novel HIV-fusion inhibitor C34-PEG4-Chol (2017) (7)
- The Omicron SARS-CoV-2 epidemic in England during February 2022 (2022) (7)
- Can iron supplementation improve cognitive functioning? (1996) (7)
- Changes in cerebral function parameters with maraviroc-intensified antiretroviral therapy in treatment naive HIV-positive individuals (2018) (7)
- Comparison of Tesio and LifeCath Twin Permanent Hemodialysis Catheters: The VyTes Randomized Trial (2014) (7)
- Characterising the persistence of RT-PCR positivity and incidence in a community survey of SARS-CoV-2 (2021) (7)
- Statistical issues in pharmacoepidemiological case-control studies. (1998) (7)
- Challenges and methodology in the incorporation of biomarkers in cancer clinical trials. (2017) (7)
- Acceptability, Usability, and Performance of Lateral Flow Immunoassay Tests for Severe Acute Respiratory Syndrome Coronavirus 2 Antibodies: REACT-2 Study of Self-Testing in Nonhealthcare Key Workers (2021) (6)
- Breakthrough SARS-CoV-2 infections in double and triple vaccinated adults and single dose vaccine effectiveness among children in Autumn 2021 in England: REACT-1 study (2022) (6)
- The Cambridge dictionary of statistics in the medical sciences, B.S. Everitt (Ed.). Cambridge University Press, Cambridge (1995), 277, ISBN 0-521-47928-2, ISBN: 0-521-47382-9 (1997) (6)
- Outcome and effect of vaccination in SARS-CoV-2 Omicron infection in hemodialysis patients: a cohort study (2022) (6)
- Complications of Central Venous Catheterization. (2016) (6)
- Dialysis Survivors: Clinical Status of Patients on Treatment for More than 10 Years (2008) (6)
- Antidepressants and suicide (2004) (6)
- Increasing SARS-CoV-2 antibody prevalence in England at the start of the second wave: REACT-2 Round 4 cross-sectional study in 160,000 adults (2021) (6)
- Lead Exposure and Children’s Intellectual Performance: the Institute of Child Health/Southampton Study (1989) (6)
- WS01-1 Effectiveness of IV compared to oral eradication therapy of Pseudomonas aeruginosa in cystic fibrosis: multicentre randomised controlled trial (TORPEDO-CF) (2019) (5)
- Levosimendan to prevent acute organ dysfunction in sepsis: the LeoPARDS RCT (2018) (5)
- The new normal? Dynamics and scale of the SARS-CoV-2 variant Omicron epidemic in England (2022) (5)
- Jim who? Recall of national leaders by elderly people in three countries (1992) (5)
- REACT-1 round 10 report: Level prevalence of SARS-CoV-2 swab-positivity in England during third national lockdown in March 2021 (2021) (5)
- MHRA's safety review randomised controlled trials submitted to the company data from placebo controlled, and suicide in adults: meta-analysis of drug Selective serotonin reuptake inhibitors (SSRIs) (2005) (5)
- Kisspeptin: a novel physiological trigger for oocyte maturation in IVF treatment (2014) (5)
- Hepcidin clearance is associated with erythropoietin requirement in stable hemodialysis patients . (2017) (5)
- Pigeonholes and mustard seeds: growing capacity to use data for society (2019) (4)
- Omicron SARS-CoV-2 epidemic in England during February 2022: A series of cross-sectional community surveys (2022) (4)
- REACT-1 round 11 report: low prevalence of SARS-CoV-2 infection in the community prior to the third step of the English roadmap out of lockdown (2021) (4)
- Intravenous or oral antibiotic treatment in adults and children with cystic fibrosis and Pseudomonas aeruginosa infection: the TORPEDO-CF RCT. (2021) (4)
- REal-time Assessment of Community Transmission (REACT) of SARS-CoV-2 virus: Study protocol [version 1;peer review: awaiting peer review] (2020) (4)
- Effects of elevating colonic propionate on liver fat content in overweight adults with non-alcoholic fatty liver disease: a pilot study (2015) (4)
- Diabetes should not dissuade arteriovenous fistula formation (2016) (4)
- Establishing causality in the assessment of safety of medicines for children (2008) (4)
- Soft Target Weight: Theory and Simulation of a Novel Haemodialysis Protocol Which Reduces Excessive Ultrafiltration (2021) (4)
- Power calculation for cohort studies with improved estimation of expected numbers of deaths (2005) (3)
- Concern about records of fibrosing colonopathy study (2001) (3)
- External data required timely response by the Trial Steering-Data Monitoring Committee for the NALoxone InVEstigation (N-ALIVE) pilot trial (2017) (3)
- Trends in SARS-CoV-2 infection prevalence during England’s roadmap out of lockdown, January to July 2021 (2022) (3)
- Meeting Report: 1st International Functional Metagenomics Workshop May 7–8, 2012, St. Jacobs, Ontario, Canada. (2013) (3)
- A methodological framework for assessing agreement between cost-effectiveness outcomes estimated using alternative sources of data on treatment costs and effects for trial-based economic evaluations (2017) (3)
- Dicing with Death: Chance, Risk and Health (2004) (3)
- Functional and quality of life outcomes of localised prostate cancer treatments (Prostate Testing for Cancer and Treatment [ProtecT] study) (2022) (2)
- Improving Child Protection by Integrating Research Evidence and Clinical Experience (2015) (2)
- A randomised, double-blind, placebo-controlled study to evaluate the efficacy of oral azithromycin as a supplement to standard care for adult patients with acute exacerbations of asthma (the AZALEA trial) (2016) (2)
- Oral steroids for long-term use in cystic fibrosis. (2013) (2)
- Statistics in Dentistry. John S. Bulman and John F. Osborn, British Dental Association, London, 1989, No. of pages: 118, Price: £6.95, $13.50 (1991) (2)
- SARS-CoV-2 Antibody Lateral Flow Assay for antibody prevalence studies following vaccine roll out: a Diagnostic Accuracy Study (2021) (2)
- REACT-1 round 15 interim report: High and rising prevalence of SARS-CoV-2 infection in England from end of September 2021 followed by a fall in late October 2021 (2021) (2)
- Genetic loci influencing C-reactive protein levels and coronary heart disease risk: results of genetic association and Mendelian randomisation study with meta-analysis in 80 614 people (2009) (2)
- Oral sodium bicarbonate in people on haemodialysis: a randomised controlled trial (2021) (2)
- Further comments on fibrosing colonopathy study (2001) (2)
- Oral potassium binders: increasing flexibility in times of crisis. (2020) (2)
- BMJ statistical errors (2004) (2)
- Acceptability, usability and performance of lateral flow immunoassay tests for SARS-CoV-2 antibodies: REACT-2 study of self-testing in non-healthcare key workers (2021) (2)
- Bayesian Approaches to Randomized Trails - Discusion (1994) (2)
- Antidepressants and suicide: Authors' reply (2004) (1)
- High energy intake and low physical activity are independent risk factors for colorectal cancer (1998) (1)
- The United Kingdom cystic fibrosis epidemiology study. (1996) (1)
- SHOULD PAIN DRAWINGS BE USED TO EVALUATE THE PSYCHOLOGICAL STATE OF LOW BACK PAIN PATIENTS? – A SYSTEMATIC REVIEW OF PAIN DRAWING LITERATURE. (2005) (1)
- Introduction: Current trends in research and regulation of microbial-based cleaning products. (2018) (1)
- REal-time Assessment of Community Transmission (REACT) of SARS-CoV-2 virus: Study protocol [version 1; peer review: 1 approved, 1 approved with reservations] (2021) (1)
- Session 29: Ovarian stimulation (2013) (1)
- Chronic forearm pain presents as a transient and indistinct pain site in a community setting: results from a UK population survey. (2008) (1)
- The Effect of Kidney Biopsy on Glomerular Filtration Rate: A Frequent Patient Concern (2020) (1)
- Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibody lateral flow assay for antibody prevalence studies following vaccination: a diagnostic accuracy study. (2021) (1)
- The cyclotron saga continues: Authors' reply (1991) (1)
- Bayesian Methods in Clinical Trials (2005) (1)
- Quantifying changes in the IFR and IHR over 23 months of the SARS-CoV-2 pandemic in England (2022) (1)
- Validity of Self-testing at Home With Rapid Severe Acute Respiratory Syndrome Coronavirus 2 Antibody Detection by Lateral Flow Immunoassay (2022) (1)
- Pre-Emptive Replacement of Water Treatment Components Improves Responsiveness to Erythropoiesis-Stimulating Agents in Maintenance Haemodialysis Patients: A Quality Improvement Report (2013) (1)
- Clinical practice guideline: Haemodialysis (2019) (1)
- Response to ‘Hepcidin levels in patients with renal disease’ (2009) (1)
- S120 Update on the UK CF Gene Therapy Consortium Multidose, Non-Viral, Gene Therapy Trial (2012) (1)
- P33 Iron deficiency independently predicts survival in idiopathic pulmonary arterial hypertension (2010) (1)
- Diagnosis of tuberculosis in dialysis and kidney transplant patients (2022) (1)
- A randomised controlled trial of physiotherapy treatments for patients with acute whiplash associated disorders (2015) (1)
- Design and Implementation of a National SARS-CoV-2 Monitoring Program in England: REACT-1 Study. (2023) (1)
- Alternatives to arteriovenous fistulas (2014) (1)
- Targeted delivery of propionate to the human colon prevents body weight and intra-abdominal adipose tissue gain in overweight adults (2014) (1)
- Complication of diagnostic pleural aspiration: Is it of value in hemodialysis patients? (2014) (1)
- Exploiting relationships between outcomes in Bayesian multivariate network meta‐analysis with an application to relapsing‐remitting multiple sclerosis (2020) (1)
- Are topical or oral ibuprofen equally effective for the treatment of chronic knee pain presenting in primary care : a randomised controlled trial with patient preference study . [ ISRCTN 79353052 ] (2015) (1)
- Use of an uncensored primary outcome in a catheter design trial? (2015) (1)
- Patient information sheets (2016) (0)
- BMJ statistical errors [letter] (2004) (0)
- Effect of initial dialysis access on post‐transplant outcome (2013) (0)
- Predictors of iron versus erythropoietin responsiveness in anemic hemodialysis patients (2022) (0)
- Results of clinical efficacy outcomes (2016) (0)
- New Cochrane Library Systematic Reviews on Cystic Fibrosis Ursodeoxycholic acid for cystic fibrosis-related liver disease (2015) (0)
- Testing the quality of Electronic Patient Record data held in the National Neonatal Research Database to support clinical trials (2019) (0)
- Vascular Access and Survival in a Large Catheter-Dominant Dialysis Program (2014) (0)
- Central venous stenosis in a transplant patient due to thyroid pathology: A teachable moment (2020) (0)
- Cystic Fibrosis Questionnaire – Revised quality-of-life questionnaire (2016) (0)
- Acknowledgement of Reviewers (2008) (0)
- Introductory Statistics: A Modelling Approach (1995). Author: J. K. Lindsey. Publisher: Oxford University Press, Oxford. Price: £ 19.50. ISBN: 0-19-852345-9 (1996) (0)
- SP617LOW DOSE UROKINASE INFUSION TO RESTORE THE PATENCY OF TUNNELED CENTRAL VEIN HAEMODIALYSIS CATHETERS (2015) (0)
- Dissociation of ferritin and hepcidin in a case of adult-onset Still’s disease (2011) (0)
- Do selective serotonin reuptake inhibitors cause suicide?: Authors' reply to Curtin and Schulz, and Healy (2005) (0)
- Title: HYDROXICLOROQUINE BLOOD CONCENTRATION IN LUPUS NEPHRITIS: A DETERMINANT OF DISEASE OUTCOME? OR: ASSOCIATIONS BETWEEN BLOOD LEVELS OF HYDROXYCHLOROQUINE AND OUTCOME IN LUPUS NEPHRITIS (2017) (0)
- Contents Vol. 36, 2013 (2014) (0)
- Anemia of Chronic Kidney Disease – Hepcidin Is a Predictor, (2011) (0)
- Response to 'The utility of multivariate analysis in the study of hepcidin' (2009) (0)
- 16th International Conference on Dialysis. Advances in Chronic Kidney Disease 2014. January 22-25, 2014, Caesars Palace, Las Vegas, Nev.: Abstracts (2013) (0)
- Response to 'The utility of multivariate analysis in the study of hepcidin' (2009) (0)
- Diagnostic value of pericardial aspiration in dialysis patients: Case report with management informed by a retrospective case series. (2022) (0)
- DELTA (Difference ELicitation in TriAls)2 advice and recommendations for researchers and funder representatives – output from literature reviews, Delphi study, workshop and stakeholder engagement (2019) (0)
- The Authors' reply (2011) (0)
- P121 Aggregate patient data meta-analyses with time-to-event endpoints: An example from surgery (1997) (0)
- Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibody lateral flow assay for antibody prevalence studies following vaccination: a diagnostic accuracy study (2022) (0)
- Behavioural responses to SARS-CoV-2 antibody testing in England: REACT-2 study (2021) (0)
- Dietetic management of people with cystic fibrosis. (2008) (0)
- The use of representative community samples to assess SARS-CoV-2 lineage competition: Alpha outcompetes Beta and wild-type in England from January to March 2021 (2023) (0)
- Bayesian analysis of neutron therapy trial (1991) (0)
- Proposal of the vote of thanks for ‘Statistics in times of increasing uncertainty’, Sylvia Richardson's Presidential Address (2022) (0)
- Parent information sheet, magnetic resonance information sheet and consent form (2016) (0)
- Creating the infrastructure: the National Neonatal Research Database (2019) (0)
- Dose preparation sheet (2016) (0)
- GeneticLociAssociatedWithC-ReactiveProtein Levels and Risk of Coronary Heart Disease (2017) (0)
- High energy, fat and protein intake are risk factors for colorectal cancer but not in patients with a family history of colorectal cancer (1998) (0)
- Distribution of primary and secondary outcomes after transformation (2016) (0)
- trials in primary care Lessons for cluster randomized trials in the twenty-first century: a systematic review of (2012) (0)
- Commentary on training and education in medical statistics, in celebration of 40 years of statistics in medicine and 50 years of the MSc medical statistics at LSHTM (2022) (0)
- Chlamydial serology in the diagnosis of pelvic inflammatory disease (1994) (0)
- Population antibody responses following COVID-19 vaccination in 212,102 individuals (2022) (0)
- 1 Blood Lead, Blood Pressure and Renal Function (1984) (0)
- G171 Survival of Preterm Infants Admitted to Neonatal Care in England: A Population-Based Study Using NHS Electronic Clinical Records (2013) (0)
- POS-513 RISK OF COVID-19 DISEASE, DIALYSIS UNIT ATTRIBUTES AND INFECTION CONTROL STRATEGY AMONG LONDON IN-CENTRE HAEMODIALYSIS PATIENTS: A RETROSPECTIVE COHORT STUDY (2021) (0)
- Even Briefer Assessment Scale for Depression (2019) (0)
- Conventional approach to a randomised controlled trial sample size calculation (2019) (0)
- Characteristics and predictors of persistent symptoms post-COVID-19 in children and young people: a large community cross-sectional study in England (2023) (0)
- Book: Dicing with Death: Chance, Risk and Health (2004) (0)
- Regular aspirin use is associated with a protective effect for colorectal cancer (1998) (0)
- THE DISTRIBUTION AND ASSOCIATIONS OF CHRONIC PAIN SITES IN A COMMUNITY SAMPLE. (2008) (0)
- Open letter to the Heads of the European Regulatory Agencies (2008) (0)
- DELTA guidance on choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial (2018) (0)
- Abstract 2161: Metformin and cancer risk: A cohort study in the UK Clinical Practice Research Datalink analyzed like a randomized trial (2014) (0)
- P76 Statistical issues in systematic reviews of chronic diseases (1997) (0)
- HEARTJNL225904 1286..1292 (0)
- Clinical Studies of Vaccine Efficacy. (2022) (0)
- Subjective global assessment is an independent predictor of cardiac ischaemia in patients with mild chronic kidney disease (2010) (0)
- Ghrelin in Cachexia Associated with End-Stage Renal Disease (2012) (0)
- Using routinely recorded clinical data for research: the Medicines for Neonates research programme (2019) (0)
- Two-year neurodevelopmental outcomes of children who were born preterm, assessed using the National Neonatal Research Database (2019) (0)
- therapy in Septic sHock ( VANISH ) VAsopressin versus Noradrenaline as Initial Protocol for a randomised controlled trial of and (2014) (0)
- Box 1 Characteristics of an ideal surrogate imaging endpoint Accurate Repeatable Reproducible Sensitive Uniqueness Prognostically important Proven interventions lead to change in the surrogate endpoint which translates into improved prognosis (0)
- Catheter Flow Monitoring Can Predict Dysfunction in Maintenance Hemodialysis (2012) (0)
- Does CRP Play a Causal Role in the Development of Coronary Heart Disease: Results of a Mendelian Randomisation Experiment Involving 128,935 People (2009) (0)
- Methods: clinical trial design and outcome measures (2016) (0)
- Results of mechanistic substudy (2016) (0)
- COMPARING AND CONTRASTING WAYS OF COMMUNICATING ABOUT PAIN – A QUALITATIVE STUDY ABOUT MUSCULOSKELETAL PAIN (2008) (0)
- Monitoring: Bayesian Data Monitoring in Clinical Trials (2005) (0)
- Central venous catheters and arrhythmia: Two unusual cases (2020) (0)
- Safety and adverse events (2016) (0)
- P1071WITHIN-PATIENT RELATIONSHIPS BETWEEN ULTRAFILTRATION AND FLUID GAINS IN HAEMODIALYSIS PATIENTS (2020) (0)
- 2 DELTA guidance on choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial (2018) (0)
- balance of benefit and harm Antidepressants and suicide: what is the (2004) (0)
- Survival, Morbidity, Sensitisation and Retransplantation Outcomes in a Cohort of Dialysis Patients After Renal Graft Loss Treated at a Single Centre With Protocolised Immunotherapy and Graft Nephrectomy By Indication.: Abstract# D2493 (2014) (0)
- Brief Assessment Scale for Depression 1994 (2004) (0)
- 1. D. R. Appleton (producer), designing a clinical trial: I. Designing a clinical trial. Video produced by D. R. Appleton, University of Newcastle, 1991. Running time: 17 mins. Price: £37, plus p and p and VAT (1993) (0)
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