Deborah F. Kelly
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Deborah F. Kellycomputer-science Degrees
Computer Science
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#13794
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Computational Linguistics
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#3265
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Machine Learning
#5954
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#6051
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Artificial Intelligence
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#6524
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Computer Science
Deborah F. Kelly's Degrees
- PhD Computer Science Stanford University
- Masters Computer Science University of California, Berkeley
- Bachelors Computer Science University of California, Berkeley
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Why Is Deborah F. Kelly Influential?
(Suggest an Edit or Addition)According to Wikipedia, Deborah F. Kelly is an American biomedical engineer who is a professor at Pennsylvania State University. Her research makes use of cryogenic electron microscopy to better understand human development and disease. She serves as President of the Microscopy Society of America.
Deborah F. Kelly's Published Works
Published Works
- A rapid and high content assay that measures cyto-ID-stained autophagic compartments and estimates autophagy flux with potential clinical applications (2015) (109)
- The Affinity Grid: a pre-fabricated EM grid for monolayer purification. (2008) (68)
- Monolayer purification: A rapid method for isolating protein complexes for single-particle electron microscopy (2008) (62)
- Toward design of magnetic nanoparticle clusters stabilized by biocompatible diblock copolymers for T₂-weighted MRI contrast. (2014) (55)
- Survival kinase genes present prognostic significance in glioblastoma (2016) (51)
- Real-time visualization of nanoparticles interacting with glioblastoma stem cells. (2015) (48)
- Strategy for the use of affinity grids to prepare non-His-tagged macromolecular complexes for single-particle electron microscopy. (2010) (44)
- 7A projection map of the S-layer protein sbpA obtained with trehalose-embedded monolayer crystals. (2007) (44)
- Visualizing viral assemblies in a nanoscale biosphere. (2013) (44)
- Molecular Structure and Dimeric Organization of the Notch Extracellular Domain as Revealed by Electron Microscopy (2010) (37)
- PIK3CB/p110&bgr; is a selective survival factor for glioblastoma (2018) (37)
- Structure of the α-Actinin–Vinculin Head Domain Complex Determined by Cryo-electron Microscopy (2006) (36)
- Visualizing virus particle mobility in liquid at the nanoscale. (2015) (35)
- Affinity grid-based cryo-EM of PKC binding to RACK1 on the ribosome. (2013) (30)
- Improved Microchip Design and Application for In Situ Transmission Electron Microscopy of Macromolecules (2013) (30)
- Patient-derived glioblastoma stem cells respond differentially to targeted therapies (2016) (30)
- Prolonged Particulate Hexavalent Chromium Exposure Suppresses Homologous Recombination Repair in Human Lung Cells. (2016) (28)
- Identification of the 1-integrin binding site on a-actinin by cryoelectron microscopy (2005) (28)
- A practical guide to the use of monolayer purification and affinity grids. (2010) (27)
- The development of affinity capture devices—a nanoscale purification platform for biological in situ transmission electron microscopy (2012) (25)
- On the freezing and identification of lipid monolayer 2-D arrays for cryoelectron microscopy. (2007) (23)
- Casein Kinase 1 Epsilon Regulates Glioblastoma Cell Survival (2018) (22)
- Conformational variability of the intracellular domain of Drosophila Notch and its interaction with Suppressor of Hairless (2007) (21)
- Liquid-Cell Electron Tomography of Biological Systems. (2019) (21)
- Capturing Enveloped Viruses on Affinity Grids for Downstream Cryo-Electron Microscopy Applications (2013) (19)
- Visualizing nanoparticle mobility in liquid at atomic resolution. (2013) (19)
- Electron microscopic analysis of rotavirus assembly-replication intermediates (2015) (19)
- Activation of transfer RNA-guanine ribosyltransferase by protein kinase C (1995) (18)
- The use of trehalose in the preparation of specimens for molecular electron microscopy. (2011) (18)
- Rotavirus core shell subdomains involved in polymerase encapsidation into virus-like particles. (2013) (17)
- Structure of the alpha-actinin-vinculin head domain complex determined by cryo-electron microscopy. (2006) (16)
- Identification of the beta1-integrin binding site on alpha-actinin by cryoelectron microscopy. (2005) (16)
- A Molecular Toolkit to Visualize Native Protein Assemblies in the Context of Human Disease (2015) (16)
- Real-time observation of protein aggregates in pharmaceutical formulations using liquid cell electron microscopy. (2017) (15)
- Structural analysis of BRCA1 reveals modification hotspot (2017) (14)
- Manganese graft ionomer complexes (MaGICs) for dual imaging and chemotherapy. (2014) (14)
- A microchip platform for structural oncology applications (2016) (14)
- Molecular Analysis of BRCA1 in Human Breast Cancer Cells Under Oxidative Stress (2017) (11)
- High‐Resolution Imaging of Human Viruses in Liquid Droplets (2021) (10)
- Structural dynamics of viral nanomachines (2014) (9)
- Structural and functional studies on the stalk of the transferrin receptor. (2009) (8)
- Microchip-based structure determination of low-molecular weight proteins using cryo-electron microscopy. (2021) (8)
- Connexin 43 confers chemoresistance through activating PI3K (2020) (8)
- In situ TEM of biological assemblies in liquid. (2013) (8)
- Cryo-SiN – An Alternative Substrate to Visualize Active Viral Assemblies (2016) (7)
- Cryo-EM-On-a-Chip: Custom-Designed Substrates for the 3D Analysis of Macromolecules. (2019) (7)
- Microchip-Based Structure Determination of Disease-Relevant p53. (2020) (6)
- Fast and easy protocol for the purification of recombinant S-layer protein for synthetic biology applications. (2011) (6)
- Molecular Surveillance of Viral Processes Using Silicon Nitride Membranes (2013) (5)
- Visualizing Macromolecules in Liquid at the Nanoscale (2016) (5)
- Preparation of Tunable Microchips to Visualize Native Protein Complexes for Single-Particle Electron Microscopy. (2018) (5)
- Liquid Cell Electron Tomography for Biomedical Applications (2018) (4)
- Capturing RNA-dependent pathways for cryo-EM analysis (2012) (4)
- Cryo-EM Reveals Architectural Diversity in Active Rotavirus Particles (2019) (4)
- Customizable Cryo-EM Chips Improve 3D Analysis of Macromolecules (2019) (4)
- Preparation of Disease-Related Protein Assemblies for Single Particle Electron Microscopy. (2017) (3)
- Molecular Analysis of BRCA 1 in Human Breast Cancer Cells Under Oxidative Stress (2017) (3)
- Tunable Substrates Improve Imaging of Viruses and Cancer Proteins (2017) (3)
- Real-time imaging of lead nanoparticles in solution – determination of the growth mechanism (2015) (2)
- Abstract 3862: Isolation and nanoscale visualization of glioblastoma stem-like cells utilizing the Notch1 receptor (2014) (1)
- Automated Tools to Advance High-Resolution Imaging in Liquid (2022) (1)
- In-situ Transmission Electron Microscopy of Biological Specimens in Liquid (2013) (1)
- Liquid-EM goes viral - visualizing structure and dynamics. (2022) (1)
- Custom Cryo-Chips as a method of enriching and imaging disease-related oncoproteins (2021) (1)
- High‐Resolution Imaging of Human Cancer Proteins Using Microprocessor Materials (2022) (1)
- A Non-Symmetric Reconstruction Technique for Transcriptionally-Active Viral Assemblies (2015) (1)
- Cryo-EM structural analysis of the SARS-CoV-2 Nucleocapsid protein (2021) (1)
- Applications and Design of Reinforced Silicon Nitride Windows for In Situ Liquid Transmission Electron Microscopy (2014) (1)
- New Applications for Affinity Grids in Preparing EM Specimens (2010) (1)
- Liquid Cell TEM Imaging Techniques and Optimization for Biological Samples (2020) (1)
- Correcting errors in the BRCA1 warning system. (2019) (1)
- Utilizing Liquid-Electron Microscopy to Visualize SARS-CoV-2 Assemblies from COVID-19 Patients (2022) (0)
- In Situ Liquid Cell Electron Microscopy: An Evolving Tool for Biomedical and Life Science Applications (2017) (0)
- Cryo-EM Reveals a Unique BRCA1 Complex in Metastasis (2018) (0)
- Microchip-Based Structure Determination of Small Proteins Using Cryo-EM (2020) (0)
- Capturing Enveloped Viruses on Affinity Grids for Downstream Cryo-Electron Tomography Applications (2013) (0)
- Isolation of Disease-relevant p53 for Cryo-Electron Microscopy Analysis (2021) (0)
- Casein Kinase 1 Epsilon Regulates Glioblastoma Cell Survival (2018) (0)
- Cryo‐Electron Microscopy: Cryo‐EM‐On‐a‐Chip: Custom‐Designed Substrates for the 3D Analysis of Macromolecules (Small 21/2019) (2019) (0)
- Abstract A18: Selectively targeting PI3K isoforms to treat glioblastoma (2020) (0)
- Visualizing Cell Adhesion Proteins Using Cryo-Electron Microscopy and 3D Reconstruction Techniques (2003) (0)
- Cryo-SiN - A New Substrate to Monitor Viral Mechanisms (2013) (0)
- Real-time Imaging of Protein Therapeutics Using Liquid Cell EM (2017) (0)
- In situ TEM imaging of Nanoparticles interacting with Glioblastoma Stem Cells (2015) (0)
- A Tunable Approach to Visualize BRCA1 Assemblies in Hereditary Breast Cancer (2015) (0)
- Lipid Monolayer Purification: a Rapid Specimen Preparation Technique for Structure Determination by Cryo-electron Microscopy (2007) (0)
- Quantitative Analysis of Viral Nanomachines in Liquid (2016) (0)
- Structural Oncology - Determining 3D Structures of Breast Cancer Assemblies (2016) (0)
- High Resolution Imaging of Virus in Liquid Droplets: The Application of Cryo-TEM Methodology to Improve Liquid-phase TEM Imaging of Biological Materials (2021) (0)
- Improving Our Vision of Nanobiology (2015) (0)
- Visualizing viral assemblies in a nanoscale biosphere3 (2012) (0)
- Exploring Calcium Phosphate Biomineralization Systems Using In Situ Liquid Phase Electron Microscopy (2022) (0)
- Complete Models of p53 Better Inform the Impact of Hotspot Mutations (2022) (0)
- Advancing High-Resolution Imaging of Virus Assemblies in Liquid and Ice. (2022) (0)
- Structural Insights of the SARS-CoV-2 Nucleocapsid Protein: Implications for the Inner-workings of Rapid Antigen Tests (2022) (0)
- Harnessing the Power of Structural Oncology (2022) (0)
- High‐Resolution Imaging of Human Viruses in Liquid Droplets (Adv. Mater. 37/2021) (2021) (0)
- Uncovering Tumor Suppressor P53 Dynamics Using Microprocessor Materials (2022) (0)
- Advancing High-resolution Imaging of Human Viruses in Liquid (2022) (0)
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