Deborah MacLatchy
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Canadian ecotoxicologist and comparative endocrinologist
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Deborah MacLatchybiology Degrees
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Biology
Deborah MacLatchy's Degrees
- PhD Biology University of Windsor
- Masters Biology University of Windsor
- Bachelors Biology University of Windsor
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Why Is Deborah MacLatchy Influential?
(Suggest an Edit or Addition)According to Wikipedia, Deborah Lynn MacLatchy is a Canadian ecotoxicologist and comparative endocrinologist. She is the seventh President and Vice-Chancellor of Wilfrid Laurier University, having formally led the International Office at the University of New Brunswick. She also served as President and Council Member of the Canadian Society of Zoologists and Chair of the Science Directors of the Canadian Rivers Institute. In 2012, MacLatchy was recognized as one of Canada’s Most Powerful Women in a Top 100 list compiled by the Women’s Executive Network.
Deborah MacLatchy's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Fundulus as the premier teleost model in environmental biology: opportunities for new insights using genomics. (2007) (287)
- The phytoestrogen beta-sitosterol alters the reproductive endocrine status of goldfish. (1995) (218)
- Altered reproduction in fish exposed to pulp and paper mill effluents: Roles of individual compounds and mill operating conditions (2008) (160)
- Pollution and parasitism in aquatic animals: a meta-analysis of effect size. (2009) (157)
- Development of a short‐term reproductive endocrine bioassay using steroid hormone and vitellogenin end points in the estuarine mummichog (Fundulus heteroclitus) (2003) (94)
- Effects on reproductive potential and endocrine status in the mummichog (Fundulus heteroclitus) after exposure to 17alpha-ethynylestradiol in a short-term reproductive bioassay. (2007) (86)
- Effects of a model androgen (methyl testosterone) and a model anti-androgen (cyproterone acetate) on reproductive endocrine endpoints in a short-term adult mummichog (Fundulus heteroclitus) bioassay. (2004) (82)
- Effects of a phytosterol mixture on male fish plasma lipoprotein fractions and testis P450scc activity. (2003) (81)
- Effects of water-borne 4-nonylphenol and 17beta-estradiol exposures during parr-smolt transformation on growth and plasma IGF-I of Atlantic salmon (Salmo salar L.). (2004) (81)
- Exposure to β‐sitosterol alters the endocrine status of goldfish differently than 17β‐estradiol (1997) (69)
- Identification and treatment of a waste stream at a bleached‐kraft pulp mill that depresses a sex steroid in the mummichog (Fundulus heteroclitus) (2001) (68)
- Effects of cortisol on aspects of 3,5,3'-triiodo-L-thyronine metabolism in rainbow trout (Oncorhynchus mykiss). (1991) (67)
- Endocrine responses of Fundulus heteroclitus to effluent from a bleached‐kraft pulp mill before and after installation of reverse osmosis treatment of a waste stream (2000) (64)
- Effects of low ambient pH and aluminum on plasma kinetics of cortisol, T3, and T4 in rainbow trout (Oncorhynchus mykiss) (1990) (54)
- In vivo implants of β-sitosterol cause reductions of reactive cholesterol pools in mitochondria isolated from gonads of male goldfish (Carassius auratus) (2003) (52)
- Effect of mercury on general and reproductive health of largemouth bass (Micropterus salmoides) from three lakes in New Jersey. (2002) (51)
- The effects of temperature and salinity on 17-α-ethynylestradiol uptake and its relationship to oxygen consumption in the model euryhaline teleost (Fundulus heteroclitus). (2013) (49)
- Isolation of compounds from bleached kraft mill recovery condensates associated with reduced levels of testosterone in mummichog (Fundulus heteroclitus) (2002) (48)
- Growth hormone stimulates hepatic thyroxine 5'-monodeiodinase activity and 3,5,3'-triiodothyronine levels in rainbow trout (Salmo gairdneri). (1990) (48)
- Modulation of steroidogenesis and estrogen signalling in the estuarine killifish (Fundulus heteroclitus) exposed to ethinylestradiol. (2010) (48)
- β-Sitosterol and 17β-estradiol alter gonadal steroidogenic acute regulatory protein (StAR) expression in goldfish, Carassius auratus (2007) (47)
- Influence of dietary lipid and carbohydrate levels and chronic 3,5,3'-triiodo-L-thyronine treatment on thyroid function in immature rainbow trout, Oncorhynchus mykiss. (1990) (46)
- Properties of T4 5'-deiodinating systems in various tissues of the rainbow trout, Oncorhynchus mykiss. (1992) (43)
- Use of paired fathead minnow (Pimephales promelas) reproductive test. Part 1: Assessing biological effects of final bleached kraft pulp mill effluent using a mobile bioassay trailer system (2006) (42)
- A Proposed Framework for Investigation of Cause for Environmental Effects Monitoring (2003) (42)
- Utility of morphological abnormalities during early‐life development of the estuarine mummichog, Fundulus heteroclitus, as an indicator of estrogenic and antiestrogenic endocrine disruption (2004) (40)
- Benzo[a]pyrene effects on reproductive endpoints in Fundulus heteroclitus. (2014) (38)
- Short-term treatment with testosterone increases plasma 3,5,3'-triiodo-L-thyronine and hepatic L-thyroxine 5'-monodeiodinase levels in arctic charr, Salvelinus alpinus. (1988) (38)
- Effects of metal mining effluent on Atlantic salmon (Salmo salar) and slimy sculpin (Cottus cognatus): using artificial streams to assess existing effects and predict future consequences. (2005) (38)
- Morphological abnormalities during early-life development of the estuarine mummichog, Fundulus heteroclitus, as an indicator of androgenic and anti-androgenic endocrine disruption. (2005) (36)
- Impact of environmental oxygen, exercise, salinity, and metabolic rate on the uptake and tissue-specific distribution of 17α-ethynylestradiol in the euryhaline teleost Fundulus heteroclitus. (2013) (35)
- Artificial Streams for Environmental Effects Monitoring (EEM): Development and Application in Canada over the Past Decade (2002) (35)
- Effects of 17alpha-ethynylestradiol on early-life development, sex differentiation and vitellogenin induction in mummichog (Fundulus heteroclitus). (2010) (34)
- Lipid dynamics in goldfish (Carassius auratus) during a period of gonadal recrudescence: Effects of β-sitosterol and 17β-estradiol exposure (2007) (34)
- The effects of 17-α-ethinylestradiol (EE2) on molecular signaling cascades in mummichog (Fundulus heteroclitus). (2013) (32)
- Identification of compounds associated with testosterone depressions in fish exposed to bleached kraft pulp and paper mill chemical recovery condensates (2006) (32)
- Canadian boreal pulp and paper feedstocks contain neuroactive substances that interact in vitro with GABA and dopaminergic systems in the brain. (2014) (30)
- Stimulation of hepatic thyroxine 5'-deiodinase activity in rainbow trout (Oncorhynchus mykiss) by Pacific salmon growth hormone. (1992) (30)
- An interlaboratory study on the use of steroid hormones in examining endocrine disruption (2001) (30)
- Use of paired fathead minnow (Pimephales promelas) reproductive test. Part 2: Source identification of biological effects at a bleached kraft pulp mill (2006) (29)
- Kraft mill effluent survey: Progress toward best management practices for reducing effects on fish reproduction (2011) (29)
- Utility of mobile, field-based artificial streams for assessing effects of pulp mill effluents on fish in the Canadian environmental effects monitoring (EEM) program (2002) (28)
- The influence of dietary protein and caloric content on thyroid function and hepatic thyroxine 5′-monodeiodinase activity in rainbow trout, Oncorhynchus mykiss (1992) (27)
- Fish assemblages on fringe coral reefs of the northern coast of Cuba near Havana Harbor. (2004) (27)
- Assessing the responses of creek chub (Semotilus atromaculatus) and pearl dace (Semotilus margarita) to metal mine effluents using in situ artificial streams in Sudbury, Ontario, Canada (2006) (26)
- Evaluating the potential of effluents and wood feedstocks from pulp and paper mills in Brazil, Canada, and New Zealand to affect fish reproduction: chemical profiling and in vitro assessments. (2012) (26)
- Investigation of Cause in Pulp and Paper Environmental Effects Monitoring (2005) (25)
- Challenges in current adult fish laboratory reproductive tests: Suggestions for refinement using a mummichog (Fundulus heteroclitus) case study (2009) (24)
- Effects of 17α-ethinylestradiol (EE2) on reproductive endocrine status in mummichog (Fundulus heteroclitus) under differing salinity and temperature conditions. (2013) (24)
- Challenges and opportunities with the use of biomarkers to predict reproductive impairment in fishes exposed to endocrine disrupting substances. (2010) (24)
- Evaluation of Short-Term Fish Reproductive Bioassays for Predicting Effects of a Canadian Bleached Kraft Mill Effluent (2010) (22)
- Thyroid hormone deiodinase systems in salmonids, and their involvement in the regulation of thyroidal status (1993) (21)
- An inter‐laboratory study on the variability in measured concentrations of 17β‐estradiol, testosterone, and 11‐ketotestosterone in white sucker: Implications and recommendations (2014) (20)
- Derivation of a continuous myogenic cell culture from an embryo of common killifish, Fundulus heteroclitus. (2014) (20)
- Investigation of de novo cholesterol synthetic capacity in the gonads of goldfish (Carassius auratus) exposed to the phytosterol beta-sitosterol (2006) (20)
- Effluent monitoring at a bleached kraft mill: Directions for best management practices for eliminating effects on fish reproduction (2011) (20)
- Sustained high temperature increases the vitellogenin response to 17α-ethynylestradiol in mummichog (Fundulus heteroclitus). (2012) (20)
- A species comparison of 17-α-ethynylestradiol uptake and tissue-specific distribution in six teleost fish. (2014) (19)
- Returning to normal? Assessing transcriptome recovery over time in male rainbow darter (Etheostoma caeruleum) liver in response to wastewater‐treatment plant upgrades (2017) (18)
- Responses in a Fathead Minnow (Pimephales promelas) Lifecycle Test and in Wild White Sucker (Catostomus commersoni) Exposed to a Canadian Bleached Kraft Mill Effluent (2010) (17)
- Detectable effect size and bioassay power of mummichog (Fundulus heteroclitus) and fathead minnow (Pimephales promelas) adult reproductive tests (2009) (17)
- A survey of Canadian mechanical pulp and paper mill effluents: Insights concerning the potential to affect fish reproduction (2013) (17)
- Intra- and extra-cellular sources of T3 binding to putative thyroid hormone receptors in liver, kidney, and gill nuclei of immature rainbow trout, Oncorhynchus mykiss. (1992) (17)
- Fundulus heteroclitus: ovarian reproductive physiology and the impact of environmental contaminants. (2011) (16)
- Isolation and identification of ligands for the goldfish testis androgen receptor in chemical recovery condensates from a Canadian bleached kraft pulp and paper mill. (2011) (15)
- Effects of kraft pulp mill condensates on plasma testosterone levels in mummichog (Fundulus heteroclitus). (2007) (15)
- Assessing non-point source pollution in agricultural regions of the upper St. John River basin using the slimy sculpin (Cottus cognatus) (2003) (14)
- A short-term mummichog (Fundulus heteroclitus) bioassay to assess endocrine responses to hormone-active compounds and mixtures (2005) (14)
- Effects of model aromatizable (17α-methyltestosterone) and non-aromatizable (5α-dihydrotestosterone) androgens on the adult mummichog (Fundulus heteroclitus) in a short-term reproductive endocrine bioassay. (2015) (12)
- Exposure to a Mixture of Zinc and Copper Decreases Survival and Fecundity of Discocotyle sagittata (Leuckart) Parasitizing Juvenile Atlantic Salmon, Salmo salar L. (2010) (12)
- How Does Reference Site Selection Influence Interpretation of Omics Data?: Evaluating Liver Transcriptome Responses in Male Rainbow Darter (Etheostoma caeruleum) across an Urban Environment. (2017) (11)
- In vivo implants of beta-sitosterol cause reductions of reactive cholesterol pools in mitochondria isolated from gonads of male goldfish (Carassius auratus). (2003) (11)
- The influence of short-term 17 beta-estradiol treatment on plasma T3 levels and in vitro hepatic T4 5'-monodeiodinase activity in immature rainbow trout, Salmo gairdneri. (1988) (11)
- Validation of a refined short-term adult fish reproductive test with improved power for mummichog (Fundulus heteroclitus) to test complex effluents. (2010) (10)
- Evaluating the potential of effluent extracts from pulp and paper mills in Canada, Brazil, and New Zealand to affect fish reproduction: Estrogenic effects in fish (2017) (10)
- Understanding the Chronic Impacts of Oil Refinery Wastewater Requires Consideration of Sediment Contributions to Toxicity (2013) (10)
- The effects of final treated effluent and in-mill waste streams from a Canadian thermomechanical pulp and paper mill on mummichog (Fundulus heteroclitus) reproduction. (2009) (9)
- Effects-based assessment in a tropical coastal system: status of bicolor damselfish (Stegastes partitus) on the north shore of Cuba. (2007) (9)
- Beta-sitosterol and 17beta-estradiol alter gonadal steroidogenic acute regulatory protein (StAR) expression in goldfish, Carassius auratus. (2007) (8)
- Absence of seasonal changes in reproductive function of cultured Atlantic salmon migrating into a Canadian river (1997) (8)
- EXPOSURE TO b-SITOSTEROL ALTERS THE ENDOCRINE STATUS OF GOLDFISH (8)
- Assessment of the potential of the rock gunnel (Pholis gunnellus) along the Atlantic coast of Canada as a species for monitoring the reproductive impacts of contaminant exposures (2007) (8)
- Lipid dynamics in goldfish (Carassius auratus) during a period of gonadal recrudescence: Effects of beta-sitosterol and 17beta-estradiol exposure. (2007) (8)
- Effects of Neutral Sulfite Semichemical Pulp Mill Effluent in the Mummichog (Fundulus heteroclitus.) Adult Fish Reproductive Test (2010) (8)
- Reproductive Steroid Responses in Fish Exposed to Pulp Mill Condensates: An Investigation of Cause Case Study (2010) (7)
- The Relationship between Organic Loading and Effects on Fish Reproduction for Pulp Mill Effluents across Canada. (2017) (7)
- Mummichog (Fundulus heteroclitus) continue to successfully produce eggs after exposure to high levels of 17α‐ethinylestradiol (2016) (6)
- Laboratory Spawning Patterns of Mummichogs, Fundulus heteroclitus (Cyprinodontiformes: Fundulidae) (2013) (6)
- Assessing Fish Community Structure in Relation to Water Quality in a Small Estuarine Stream Receiving Oil Refinery Effluent (2007) (6)
- Development of a short-term in situ caging methodology to assess long-term effects of industrial and municipal discharges on salmon smolts. (2005) (5)
- Assessing recovery of in vitro steroid production in male rainbow darter (Etheostoma caeruleum) in response to municipal wastewater treatment plant infrastructure changes (2018) (5)
- Thyroid hormone: deiodinase and receptor assays (1994) (4)
- Mummichog (Fundulus heteroclitus) are less sensitive to 17α-ethinylestradiol (EE2) than other common model teleosts: a comparative review of reproductive effects. (2019) (4)
- Comparison of steroidogenic gene expression in mummichog (Fundulus heteroclitus) testis tissue following exposure to aromatizable or non-aromatizable androgens. (2019) (3)
- Evaluation of Short-Term Fish Reproductive Bioassays for Predicting Effects of a Canadian Bleached Kraft Mill Effl uent (2011) (3)
- Altered Reproduction in Fish Exposed to Pulp and Paper Mill Effluents: Roles of Individual Compounds and Mill Operating Conditions-Critical Review (2007) (3)
- Fish Short-term Reproduction Assay Peer Review – EPA Response (2008) (0)
- Ethinylestradiol depresses gonadal steroidogenesis downstream of the rate-limiting step in mummichog (Fundulus heteroclitus) (2007) (0)
- Reproductive status of walleye (Sander vitreus) and lake whitefish (Coregonus clupeaformis) in two large, shallow Canadian subarctic lakes (2020) (0)
- Physiological effects of 5α-dihydrotestosterone in male mummichog (Fundulus heteroclitus) are dose and time dependent. (2019) (0)
- Considering Fish as Recipients of Ecosystem Services Provides a Framework to Formally Link Baseline, Development, and Post-operational Monitoring Programs and Improve Aquatic Impact Assessments for Large Scale Developments (2022) (0)
- Acknowledgements for Refereeing (2004) (0)
- Fish Endocrinology, Manfred Reinecke, Giacomo Zaccone, B.G. Kapoor (Eds.). Science Publishers (2006), (2 vols.) US $ 135.00, 886 pages, ISBN: 1-57808-318-4 (2007) (0)
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