Dena Dubal
#85,099
Most Influential Person Now
American neurodegenerative disease researcher
Dena Dubal's AcademicInfluence.com Rankings
Dena Dubalphilosophy Degrees
Philosophy
#11087
World Rank
#15223
Historical Rank
#2090
USA Rank
Logic
#8964
World Rank
#11297
Historical Rank
#1531
USA Rank
Dena Dubalbiology Degrees
Biology
#11990
World Rank
#15435
Historical Rank
#2603
USA Rank
Neuroscience
#2480
World Rank
#2545
Historical Rank
#297
USA Rank
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Philosophy Biology
Dena Dubal's Degrees
- Doctorate Medicine University of California, San Francisco
- PhD Neuroscience University of California, San Francisco
Why Is Dena Dubal Influential?
(Suggest an Edit or Addition)According to Wikipedia, Dena Dubal is the David A. Coulter Endowed Chair in Ageing and Neurodegenerative Disease at University of California, San Francisco. Dubal has demonstrated that the hormone Klotho can enhance cognition and protect the brain from neurodegenerative decline.
Dena Dubal's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Estradiol Protects against Ischemic Injury (1998) (566)
- Estrogen receptor α, not β, is a critical link in estradiol-mediated protection against brain injury (2001) (508)
- Estradiol Modulates bcl-2 in Cerebral Ischemia: A Potential Role for Estrogen Receptors (1999) (467)
- Reversing EphB2 depletion rescues cognitive functions in Alzheimer model (2011) (391)
- Estrogen receptor alpha, not beta, is a critical link in estradiol-mediated protection against brain injury. (2001) (286)
- Estrogens: Trophic and Protective Factors in the Adult Brain (2001) (237)
- Life extension factor klotho enhances cognition. (2014) (225)
- Estradiol is a protective factor in the adult and aging brain: understanding of mechanisms derived from in vivo and in vitro studies (2001) (212)
- Astrocytic adenosine receptor A2A and Gs-coupled signaling regulate memory (2014) (207)
- Differential modulation of estrogen receptors (ERs) in ischemic brain injury: a role for ERalpha in estradiol-mediated protection against delayed cell death. (2006) (183)
- Minireview: Neuroprotective Effects of Estrogen-New Insights into Mechanisms of Action. (2001) (153)
- Estradiol Attenuates Programmed Cell Death after Stroke-Like Injury (2003) (148)
- Are estrogens protective or risk factors in brain injury and neurodegeneration? Reevaluation after the Women's health initiative. (2005) (147)
- Sex biology contributions to vulnerability to Alzheimer's disease: A think tank convened by the Women's Alzheimer's Research Initiative (2016) (145)
- Life Extension Factor Klotho Prevents Mortality and Enhances Cognition in hAPP Transgenic Mice (2015) (143)
- Estradiol protects against injury-induced cell death in cortical explant cultures: a role for estrogen receptors (2000) (131)
- Neuroprotective effects of estradiol in middle-aged female rats. (2001) (128)
- Collagen VI protects neurons against Aβ toxicity (2009) (121)
- Minireview: neuroprotective effects of estrogen-new insights into mechanisms of action. (2001) (120)
- Human P301L-Mutant Tau Expression in Mouse Entorhinal-Hippocampal Network Causes Tau Aggregation and Presynaptic Pathology but No Cognitive Deficits (2012) (109)
- Neuroendocrine modulation and repercussions of female reproductive aging. (2002) (108)
- Neuroprotective Effects of Estradiol in Middle-Aged Female Rats** Supported in part by NIH Grant AG-02224 (to P.M.W.), NIH Predoctoral fellowship T32-AG-00242 (to D.B.D.), Merck/American Federation for Aging Research Scholarship (to D.B.D.), and Glenn Foundation/American Federation for Aging Researc (2001) (95)
- Estradiol Protects Against Ischemic Brain Injury in Middle-Aged Rats1 (2000) (90)
- Neuroendocrine influences and repercussions of the menopause. (1999) (87)
- Estradiol is a neuroprotective factor in in vivo and in vitro models of brain injury (2000) (75)
- Peripheral Elevation of a Klotho Fragment Enhances Brain Function and Resilience in Young, Aging, and α-Synuclein Transgenic Mice (2017) (72)
- A second X chromosome contributes to resilience in a mouse model of Alzheimer’s disease (2020) (69)
- Variation in longevity gene KLOTHO is associated with greater cortical volumes (2015) (68)
- Longevity factor klotho and chronic psychological stress (2015) (55)
- Systemic klotho is associated with KLOTHO variation and predicts intrinsic cortical connectivity in healthy human aging (2016) (49)
- BDNF Val66Met predicts cognitive decline in the Wisconsin Registry for Alzheimer's Prevention (2017) (47)
- Estradiol Differentially Regulates c-Fos after Focal Cerebral Ischemia (2003) (41)
- Estradiol: a protective and trophic factor in the brain. (1999) (41)
- Sex and gonadal hormones in mouse models of Alzheimer’s disease: what is relevant to the human condition? (2012) (41)
- Sex difference in Alzheimer's disease: An updated, balanced and emerging perspective on differing vulnerabilities. (2020) (38)
- Female XX sex chromosomes increase survival and extend lifespan in aging mice (2018) (36)
- KLOTHO heterozygosity attenuates APOE4-related amyloid burden in preclinical AD (2019) (35)
- Network dysfunction in α‐synuclein transgenic mice and human Lewy body dementia (2015) (35)
- A case of paraneoplastic myelopathy associated with the neuromyelitis optica antibody (2008) (34)
- Effects of Aerobic Exercise Training on Systemic Biomarkers and Cognition in Late Middle-Aged Adults at Risk for Alzheimer’s Disease (2021) (30)
- Cognitive aging is not created equally: differentiating unique cognitive phenotypes in “normal” adults (2019) (25)
- Estrogen and neuroprotection: from clinical observations to molecular mechanisms (2002) (21)
- Ovarian Cycle Stages Modulate Alzheimer-Related Cognitive and Brain Network Alterations in Female Mice (2018) (20)
- Neural-Derived Extracellular Vesicles in Clinical Trials: Message in a Bottle. (2019) (13)
- Sexual dimorphism of physical activity on cognitive aging: Role of immune functioning (2020) (12)
- Sex-Specific Association of the X Chromosome With Cognitive Change and Tau Pathology in Aging and Alzheimer Disease (2021) (11)
- Sex-Stratified Single-Cell RNA-Seq Analysis Identifies Sex-Specific and Cell Type-Specific Transcriptional Responses in Alzheimer’s Disease Across Two Brain Regions (2021) (10)
- Longevity Gene KLOTHO and Alzheimer Disease-A Better Fate for Individuals Who Carry APOE ε4. (2020) (10)
- Age-Related Tau Burden and Cognitive Deficits Are Attenuated in KLOTHO KL-VS Heterozygotes. (2021) (10)
- T‐cell lymphoproliferative disorder following mycophenolate treatment for myasthenia gravis (2009) (10)
- Apolipoprotein E ε4 and Risk Factors for Alzheimer Disease-Let's Talk About Sex. (2017) (8)
- The Way of Tau: Secretion and Synaptic Dysfunction. (2018) (6)
- Deep phenotyping of Alzheimer’s disease leveraging electronic medical records identifies sex-specific clinical associations (2022) (6)
- Activin gene expression increases after stroke injury: Modulation by estradiol (2004) (6)
- KL1 Domain of Longevity Factor Klotho Mimics the Metabolome of Cognitive Stimulation and Enhances Cognition in Young and Aging Mice (2022) (5)
- Sex-Stratified Single-Cell RNA-Seq Analysis Identifies Sex-Specific and Cell Type-Specific Transcriptional Responses in Alzheimer’s Disease Across Two Brain Regions (2021) (4)
- Cord blood klotho levels are inversely associated with leptin in healthy Latino neonates at risk for obesity (2018) (4)
- In Vitro and In Vivo Approaches to the Study of the Neuroprotective Actions of Estradiol (2001) (2)
- KIBRA, MTNR1B, and FKBP5 genotypes are associated with decreased odds of incident delirium in elderly post-surgical patients (2022) (2)
- The Interaction between Ventricle to Brain Ratio and Serum Klotho on Cognition in Older Adults at Risk for Alzheimer’s Disease (2021) (1)
- Age-Related Tau Burden and Cognitive Deficits Are Attenuated in KLOTHO KL-VS Heterozygotes. (2021) (1)
- Circulating klotho is elevated in cerebrospinal fluid, but not serum, among KLOTHO KL‐VS allele carriers at risk for Alzheimer’s disease (2021) (1)
- X chromosome factor Kdm6a enhances cognition independent of its demethylase function in the aging XY male brain. (2023) (1)
- P1-465: Role of collagen VI in Alzheimer's disease: Potential mechanisms of protection (2008) (1)
- Circulating Klotho Is Higher in Cerebrospinal Fluid than Serum and Elevated Among KLOTHO Heterozygotes in a Cohort with Risk for Alzheimer's Disease. (2022) (1)
- Deep clinical phenotyping of Alzheimer's Disease Patients Leveraging Electronic Medical Records Data Identifies Sex-Specific Clinical Associations (2021) (1)
- Best of JAMA Neurology 2019: Research That Drives Practice. (2020) (1)
- Sex and gonadal hormones in mouse models of Alzheimer’s disease: what is relevant to the human condition? (2012) (1)
- Are Estrogens Protective or Risk Factors in the Brain? Insights Derived From Animal Models (2004) (1)
- Neuroprotective actions of estradiol in the adult and aging brain: Potential mechanisms of action (2000) (0)
- QOL-47. ApoE4 AS A GENETIC PREDICTOR FOR NEUROCOGNITIVE OUTCOMES IN PEDIATRIC BRAIN TUMOR SURVIVORS (2018) (0)
- Deep phenotyping of Alzheimer’s disease leveraging electronic medical records identifies sex-specific clinical associations (2022) (0)
- AD‐associated CSF biomolecular changes are attenuated in KL‐VS heterozygotes (2022) (0)
- Longevity factor klotho and resistance to cognitive deficits in a transgenic mouse model and in individuals with Parkinson’s disease (2020) (0)
- X chromosome factor Kdm6a enhances memory independent of its demethylase function in the aging XY male brain (2022) (0)
- KIBRA, MTNR1B, and FKBP5 genotypes are associated with decreased odds of incident delirium in elderly post-surgical patients (2022) (0)
- TIAMUTIN RESIDUES IN BUFFALO AND COW MILK AFTER INTRA-MAMMARY INFUSION (1999) (0)
- NCOG-71. GENOME ASSOCIATIONS WITH NEUROCOGNITIVE OUTCOMES, CEREBRAL MICROBLEEDS (CMBS), AND BRAIN VOLUME AND WHITE MATTER (WM) CHANGES IN PEDIATRIC BRAIN TUMOR SURVIVORS (2020) (0)
- Female resilience in brain aging (2021) (0)
- LONGEVITY GENE KLOTHO ALTERS APOE4-RELATED CORTICAL THINNING: FINDINGS FROM THE WISCONSIN REGISTRY FOR ALZHEIMER’S PREVENTION (2016) (0)
- Sugar sweetened beverage consumption is positively associated with Klotho levels at two years of age in LatinX youth (2021) (0)
- Rare APOE Missense Variants-Can We Overcome APOE ε4 and Alzheimer Disease Risk? (2022) (0)
- Mechanisms of sex-based neuropathologies (2004) (0)
- Systemic klotho is associated with KLOTHO variation and predicts intrinsic cortical connectivity in healthy human aging (2016) (0)
- X CHROMOSOME-DERIVED MECHANISMS OF SEX DIFFERENCES IN LIFESPAN AND BRAIN AGING (2022) (0)
- Colloquium C04: Estrogen and Neurodegenerative Diseases: A Protective Role? (2003) (0)
- Reversible Suppression of Electrocerebral Activity (2013) (0)
- An Integrated Analysis of Clinical, Genomic, and Imaging Features Reveals Predictors of Neurocognitive Outcomes in a Longitudinal Cohort of Pediatric Cancer Survivors, Enriched with CNS Tumors (Rad ART Pro) (2022) (0)
- QOL-53. GENOME ASSOCIATIONS WITH NEUROCOGNITIVE OUTCOMES, CEREBRAL MICROBLEEDS (CMBS), AND BRAIN VOLUME AND WHITE MATTER (WM) CHANGES IN PEDIATRIC BRAIN TUMOR SURVIVORS (2020) (0)
- Pathways to brain resilience (2019) (0)
- Ms Jones: reflections on aging, illness, and medicine. (2003) (0)
- LONGEVITY GENE KLOTHO ALTERS APOE4-RELATED CORTICAL THINNING: FINDINGS FROM THE WISCONSIN REGISTRY FOR ALZHEIMER’S PREVENTION (2016) (0)
- The mitochondrial unfolded protein response regulates hippocampal neural stem cell aging. (2023) (0)
- The maternal X chromosome impairs cognition and accelerates brain aging through epigenetic modulation in female mice (2022) (0)
- 4329 Investigating the role of Klotho in neurocognitive outcomes, brain volumes, and white matter changes in pediatric brain tumor survivors (2020) (0)
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What Schools Are Affiliated With Dena Dubal?
Dena Dubal is affiliated with the following schools:
