Deng Hongkui
#116,366
Most Influential Person Now
Chinese immunologist and stem cell researcher
Deng Hongkui's AcademicInfluence.com Rankings
Deng Hongkuilaw Degrees
Law
#3196
World Rank
#4026
Historical Rank
Common Law
#204
World Rank
#221
Historical Rank
Deng Hongkuibiology Degrees
Biology
#15175
World Rank
#19099
Historical Rank
Immunology
#1049
World Rank
#1075
Historical Rank
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Law Biology
Deng Hongkui's Degrees
- Bachelors Medicine Peking University
- PhD Immunology Peking University
Why Is Deng Hongkui Influential?
(Suggest an Edit or Addition)According to Wikipedia, Deng Hongkui is a Chinese immunologist and stem cell researcher. He is a Changjiang Professor, the Boya Chair Professor, and Director of the Institute of Stem Cell Research at Peking University. He was awarded US$1.9 million by the Bill & Melinda Gates Foundation for his research on vaccines for HIV and hepatitis C. In 2017, he and Chen Hu engineered resistance to HIV in mice using CRISPR gene editing, and for the first time used the technique on an AIDS patient.
Deng Hongkui's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Pluripotent Stem Cells Induced from Mouse Somatic Cells by Small-Molecule Compounds (2013) (1137)
- Directed differentiation of human embryonic stem cells into functional hepatic cells (2007) (612)
- Generation of rat and human induced pluripotent stem cells by combining genetic reprogramming and chemical inhibitors. (2009) (585)
- Highly efficient differentiation of human ES cells and iPS cells into mature pancreatic insulin-producing cells (2009) (578)
- Generation of induced pluripotent stem cells from adult rhesus monkey fibroblasts. (2008) (480)
- Two supporting factors greatly improve the efficiency of human iPSC generation. (2008) (469)
- Efficient generation of hepatocyte-like cells from human induced pluripotent stem cells (2009) (449)
- Genomic Characterization of Severe Acute Respiratory Syndrome-Related Coronavirus in European Bats and Classification of Coronaviruses Based on Partial RNA-Dependent RNA Polymerase Gene Sequences (2010) (362)
- Small Molecules Blocking the Entry of Severe Acute Respiratory Syndrome Coronavirus into Host Cells (2004) (355)
- In vitro derivation of functional insulin-producing cells from human embryonic stem cells (2007) (342)
- Direct lineage reprogramming: strategies, mechanisms, and applications. (2015) (331)
- Generation of iPSCs from mouse fibroblasts with a single gene, Oct4, and small molecules (2011) (326)
- Small-Molecule-Driven Direct Reprogramming of Mouse Fibroblasts into Functional Neurons. (2015) (324)
- Derivation of Pluripotent Stem Cells with In Vivo Embryonic and Extraembryonic Potency (2017) (320)
- Short-term BMP-4 treatment initiates mesoderm induction in human embryonic stem cells. (2008) (307)
- Human hepatocytes with drug metabolic function induced from fibroblasts by lineage reprogramming. (2014) (286)
- Induction of Pluripotency in Mouse Somatic Cells with Lineage Specifiers (2013) (282)
- MEK/ERK signaling contributes to the maintenance of human embryonic stem cell self-renewal. (2007) (257)
- CRISPR-Edited Stem Cells in a Patient with HIV and Acute Lymphocytic Leukemia. (2019) (241)
- Noggin and bFGF cooperate to maintain the pluripotency of human embryonic stem cells in the absence of feeder layers. (2005) (239)
- Claudin-6 and Claudin-9 Function as Additional Coreceptors for Hepatitis C Virus (2007) (231)
- Humanized mice for modeling human infectious disease: challenges, progress, and outlook. (2009) (221)
- CD81 and Claudin 1 Coreceptor Association: Role in Hepatitis C Virus Entry (2008) (213)
- Inducing Embryonic Stem Cells to Differentiate into Pancreatic β Cells by a Novel Three‐Step Approach with Activin A and All‐Trans Retinoic Acid (2005) (203)
- Regulation of Apoptosis and Differentiation by p53 in Human Embryonic Stem Cells* (2007) (203)
- A XEN-like State Bridges Somatic Cells to Pluripotency during Chemical Reprogramming (2015) (185)
- Analysis of ACE2 in polarized epithelial cells: surface expression and function as receptor for severe acute respiratory syndrome-associated coronavirus. (2006) (169)
- Difference in Receptor Usage between Severe Acute Respiratory Syndrome (SARS) Coronavirus and SARS-Like Coronavirus of Bat Origin (2007) (163)
- CRISPR/Cas9-Mediated CCR5 Ablation in Human Hematopoietic Stem/Progenitor Cells Confers HIV-1 Resistance In Vivo. (2017) (156)
- Identification of an Antigenic Determinant on the S2 Domain of the Severe Acute Respiratory Syndrome Coronavirus Spike Glycoprotein Capable of Inducing Neutralizing Antibodies (2004) (143)
- Expression cloning of functional receptor used by SARS coronavirus (2004) (143)
- Importance of cholesterol-rich membrane microdomains in the interaction of the S protein of SARS-coronavirus with the cellular receptor angiotensin-converting enzyme 2 (2008) (137)
- Induction of oocyte-like cells from mouse embryonic stem cells by co-culture with ovarian granulosa cells. (2007) (131)
- Generation of Blastocyst-like Structures from Mouse Embryonic and Adult Cell Cultures (2019) (130)
- Elimination of senescent cells by β-galactosidase-targeted prodrug attenuates inflammation and restores physical function in aged mice (2020) (126)
- A novel chemical-defined medium with bFGF and N2B27 supplements supports undifferentiated growth in human embryonic stem cells. (2006) (123)
- Characterization of classical swine fever virus entry by using pseudotyped viruses: E1 and E2 are sufficient to mediate viral entry. (2004) (121)
- Neutralizing Antibodies in Patients with Severe Acute Respiratory Syndrome-Associated Coronavirus Infection (2004) (120)
- Targeted disruption of Smad4 in mouse epidermis results in failure of hair follicle cycling and formation of skin tumors. (2005) (115)
- Generation of naive induced pluripotent stem cells from rhesus monkey fibroblasts. (2014) (114)
- Neutralizing antibodies in patients with severe acute respiratory syndrome-associated coronavirus infection. (2004) (113)
- Long-term functional maintenance of primary human hepatocytes in vitro (2019) (111)
- Generation of homogeneous PDX1(+) pancreatic progenitors from human ES cell-derived endoderm cells. (2010) (111)
- Directed differentiation of human embryonic stem cells into thymic epithelial progenitor-like cells reconstitutes the thymic microenvironment in vivo. (2013) (109)
- Repopulation efficiencies of adult hepatocytes, fetal liver progenitor cells, and embryonic stem cell-derived hepatic cells in albumin-promoter-enhancer urokinase-type plasminogen activator mice. (2009) (107)
- Highly infectious SARS-CoV pseudotyped virus reveals the cell tropism and its correlation with receptor expression (2004) (107)
- Suppression of SARS-CoV entry by peptides corresponding to heptad regions on spike glycoprotein (2004) (104)
- Differential Sensitivity of Bat Cells to Infection by Enveloped RNA Viruses: Coronaviruses, Paramyxoviruses, Filoviruses, and Influenza Viruses (2013) (104)
- The ISSCR Guidelines for Human Embryonic Stem Cell Research (2007) (99)
- Derivation and Characterization of Hepatic Progenitor Cells from Human Embryonic Stem Cells (2009) (98)
- Single-Cell RNA-Seq Reveals Dynamic Early Embryonic-like Programs during Chemical Reprogramming. (2018) (94)
- Piglets cloned from induced pluripotent stem cells (2012) (86)
- Primordial Germ Cell Specification from Embryonic Stem Cells (2008) (80)
- CD24: A Novel Surface Marker for PDX1‐Positive Pancreatic Progenitors Derived from Human Embryonic Stem Cells (2011) (73)
- TGFβ inhibition enhances the generation of hematopoietic progenitors from human ES cell-derived hemogenic endothelial cells using a stepwise strategy (2011) (71)
- Direct Reprogramming of Fibroblasts via a Chemically Induced XEN-like State. (2017) (67)
- Generation of pancreatic insulin-producing cells from rhesus monkey induced pluripotent stem cells (2011) (67)
- Identification and Characterization of Bmi-1-responding Element within the Human p16 Promoter* (2010) (61)
- Pluripotent stem cells induced from mouse neural stem cells and small intestinal epithelial cells by small molecule compounds (2015) (59)
- Chimeric contribution of human extended pluripotent stem cells to monkey embryos ex vivo (2021) (58)
- A Novel Sorting Signal for Intracellular Localization Is Present in the S Protein of a Porcine Coronavirus but Absent from Severe Acute Respiratory Syndrome-associated Coronavirus* (2004) (54)
- Patients beware: commercialized stem cell treatments on the web. (2010) (51)
- Induction of neutralizing antibody against human immunodeficiency virus type 1 (HIV-1) by immunization with gp41 membrane-proximal external region (MPER) fused with porcine endogenous retrovirus (PERV) p15E fragment. (2006) (50)
- GATA family members as inducers for cellular reprogramming to pluripotency (2015) (47)
- Holoclone Forming Cells from Pancreatic Cancer Cells Enrich Tumor Initiating Cells and Represent a Novel Model for Study of Cancer Stem Cells (2011) (46)
- Pluripotin Combined with Leukemia Inhibitory Factor Greatly Promotes the Derivation of Embryonic Stem Cell Lines from Refractory Strains (2009) (46)
- Systematically labeling developmental stage-specific genes for the study of pancreatic β-cell differentiation from human embryonic stem cells (2014) (45)
- Increased reactive oxygen species and exhaustion of quiescent CD34-positive bone marrow cells may contribute to poor graft function after allotransplants (2016) (44)
- Live Offspring Produced by Mouse Oocytes Derived from Premeiotic Fetal Germ Cells1 (2006) (43)
- Promotion of the efficient metabolic maturation of human pluripotent stem cell-derived hepatocytes by correcting specification defects (2012) (42)
- Enhancement of the in vivo persistence and antitumor efficacy of CD19 chimeric antigen receptor T cells through the delivery of modified TERT mRNA (2015) (41)
- Coexpression of Pdx1 and betacellulin in mesenchymal stem cells could promote the differentiation of nestin-positive epithelium-like progenitors and pancreatic islet-like spheroids. (2008) (40)
- Failure of hepatocyte marker-expressing hematopoietic progenitor cells to efficiently convert into hepatocytes in vitro. (2006) (37)
- Chimeric Antigen Receptor–modified T Cells Repressed Solid Tumors and Their Relapse in an Established Patient-derived Colon Carcinoma Xenograft Model (2018) (37)
- Powering reprogramming with vitamin C. (2010) (36)
- Netrin-1 regulates somatic cell reprogramming and pluripotency maintenance (2015) (36)
- A two-step lineage reprogramming strategy to generate functionally competent human hepatocytes from fibroblasts (2019) (35)
- Mouse lysocardiolipin acyltransferase controls the development of hematopoietic and endothelial lineages during in vitro embryonic stem-cell differentiation. (2007) (35)
- Establishment of intestinal organoid cultures modeling injury-associated epithelial regeneration (2021) (34)
- Retinoic acid enhances the generation of hematopoietic progenitors from human embryonic stem cell-derived hemato-vascular precursors. (2010) (33)
- Mature oocytes derived from purified mouse fetal germ cells. (2007) (33)
- Generation of pancreatic islet cells from human embryonic stem cells (2009) (33)
- In vitro development of mouse fetal germ cells into mature oocytes. (2007) (32)
- Short-term BMP4 treatment initiates mesoderm induction in human embryonic stem cells (2007) (32)
- GATA factors induce mouse embryonic stem cell differentiation toward extraembryonic endoderm. (2007) (30)
- Comparison of vesicular stomatitis virus pseudotyped with the S proteins from a porcine and a human coronavirus. (2009) (30)
- Developmental stage related patterns of codon usage and genomic GC content: searching for evolutionary fingerprints with models of stem cell differentiation (2007) (29)
- Baculovirus surface display of SARS coronavirus (SARS-CoV) spike protein and immunogenicity of the displayed protein in mice models. (2006) (29)
- Hepatic spheroids derived from human induced pluripotent stem cells in bio-artificial liver rescue porcine acute liver failure (2019) (28)
- In vivo chemical reprogramming of astrocytes into neurons (2021) (28)
- Functional cloning of IGFBP-3 from human microvascular endothelial cells reveals its novel role in promoting proliferation of primitive CD34+CD38- hematopoietic cells in vitro. (2003) (28)
- Pancreas-specific Pten deficiency causes partial resistance to diabetes and elevated hepatic AKT signaling (2009) (26)
- Differentiation of mouse nuclear transfer embryonic stem cells into functional pancreatic beta cells (2008) (26)
- The Vascular Disrupting Agent CA4P Improves the Antitumor Efficacy of CAR-T Cells in Preclinical Models of Solid Human Tumors. (2020) (25)
- P21 cip-Overexpression in the Mouse β Cells Leads to the Improved Recovery from Streptozotocin-Induced Diabetes (2009) (24)
- A mouse model of inducible liver injury caused by tet-on regulated urokinase for studies of hepatocyte transplantation. (2009) (24)
- Identification and characterization of label-retaining cells in mouse pancreas. (2007) (24)
- Simple and efficient production of mice derived from embryonic stem cells aggregated with tetraploid embryos (2005) (23)
- Small molecule-induced cellular fate reprogramming: promising road leading to Rome. (2018) (23)
- Telomere Reprogramming and Maintenance in Porcine iPS Cells (2013) (23)
- Targeting JNK pathway promotes human hematopoietic stem cell expansion (2019) (23)
- Angiotensin-converting enzyme 2 (ACE2) from raccoon dog can serve as an efficient receptor for the spike protein of severe acute respiratory syndrome coronavirus. (2009) (21)
- Mouse SCNT ESCs Have Lower Somatic Mutation Load Than Syngeneic iPSCs (2014) (20)
- Ethics: China already has clear stem-cell guidelines (2006) (18)
- NestinnegCD24low/− Population From Fetal Nestin-EGFP Transgenic Mice Enriches the Pancreatic Endocrine Progenitor Cells (2005) (18)
- Lineage Specifiers: New Players in the Induction of Pluripotency (2013) (17)
- Generation of human hepatocytes from extended pluripotent stem cells (2020) (16)
- Rapid generation of gene-targeted EPS-derived mouse models through tetraploid complementation (2018) (14)
- The proteasomal inhibitor MG132 increases the efficiency of mouse embryo production after cloning by electrofusion. (2005) (13)
- A human endothelial cell feeder system that efficiently supports the undifferentiated growth of mouse embryonic stem cells. (2008) (13)
- Mouse oocytes derived from fetal germ cells are competent to support the development of embryos by in vitro fertilization (2006) (13)
- Correction: Telomere Reprogramming and Maintenance in Porcine iPS Cells (2013) (10)
- ADAM17 is an essential attachment factor for classical swine fever virus (2021) (10)
- Injectable Porous Microchips with Oxygen Reservoirs and an Immune-Niche Enhance the Efficacy of CAR T Cell Therapy in Solid Tumors. (2020) (10)
- Elicitation of neutralizing antibodies by intranasal administration of recombinant vesicular stomatitis virus expressing human immunodeficiency virus type 1 gp120 (2005) (10)
- Effective treatment of SARS-CoV-2-infected rhesus macaques by attenuating inflammation (2020) (8)
- Chemically defined and xeno-free culture condition for human extended pluripotent stem cells (2021) (8)
- Engineered T lymphocytes eliminate lung metastases in models of pancreatic cancer (2018) (8)
- The heterogeneity and dynamic equilibrium of rat embryonic stem cells (2011) (8)
- Isolation and characterization of liver epithelial progenitor cells from normal adult rhesus monkeys (Macaca mulatta) (2009) (8)
- Identification of potential nuclear reprogramming and differentiation factors by a novel selection method for cloning chromatin-binding proteins. (2004) (7)
- Chimeric contribution of human extended pluripotent stem cells to monkey embryos ex vivo (2021) (7)
- Induction of Pluripotency in Mouse Somatic Cells with Lineage Specifiers (2015) (6)
- Efficient derivation of extended pluripotent stem cells from NOD-scid Il2rg−/− mice (2018) (6)
- Efficient derivation of embryonic stem cells from NOD-scid Il2rg−/− mice (2015) (5)
- Serial nuclear transfer improves the developmental potential of mouse embryos cloned from oocytes matured in a protein‐free medium (2007) (5)
- Human pluripotent stem cell-derived eosinophils reveal potent cytotoxicity against solid tumors (2021) (5)
- Chemical reprogramming: the CiPSCs and the CiNs (2017) (5)
- Rbm46 regulates trophectoderm differentiation by stabilizing Cdx2 mRNA in early mouse embryos. (2015) (4)
- Cell fate conversion—from the viewpoint of small molecules and lineage specifiers (2016) (4)
- Enhancement of the in vivo persistence and antitumor efficacy of CD19 chimeric antigen receptor T cells through the delivery of modified TERT mRNA (2016) (3)
- Requirements for human‐induced pluripotent stem cells (2022) (2)
- Chemically Defined and Xeno-free Culturing Protocol for Human Extended Pluripotent Stem Cells (2021) (1)
- YY1 safeguard multidimensional epigenetic landscape associated with extended pluripotency (2022) (1)
- embryonic stem cells Short-term BMP-4 treatment initiates mesoderm induction in human (2012) (1)
- Cell Injury , Repair , Aging and Apoptosis A Mouse Model of Inducible Liver Injury Caused by TetOn Regulated Urokinase for Studies of Hepatocyte Transplantation (2009) (1)
- Abstract 430: An Acyltransferase Controls The Generation Of Hematopoietic And Endothelial Lineages In Zebrafish And Mouse ES Cells (2007) (1)
- Mouse oocytes derived from fetal germ cells are competent to support the development of embryos by in vitro fertilization (2008) (1)
- Reprogramming cell fate and function (2014) (0)
- stem-cell differentiation hematopoietic and endothelial lineages during in vitro embryonic Mouse lysocardiolipin acyltransferase controls the development of (2010) (0)
- Nanog reporter system in mouse embryonic stem cells based on highly efficient BAC homologous recombination (2007) (0)
- Correction to: Efficient derivation of extended pluripotent stem cells from NOD-scid Il2rg−/− mice (2018) (0)
- Human Embryonic Stem Cells: The Practical Handbook Edited by Stephen Sullivan, Chad A. Cowan, and Kevin Eggan (2008) (0)
- Attempts for deriving extended pluripotent stem cells from common marmoset embryonic stem cells (2022) (0)
- Retraction for Shen et al., Oocyte‐Like Cells Can Be Differentiated from Mouse Embryonic Stem Cells Induced by the Stage‐Specific Ovary‐Conditioned Medium and Cocultured Ovary Somatic Cells in Vitro (2007) (0)
- N-terminal of L protein of vesicular stomatitis virus contains a new signal sequence (2003) (0)
- Mouse Lycat Controls the Development of Hematopoietic and Endothelial Lineages during in vitro ES Cell Differentiation (2007) (0)
- CUMULUS CELLS PROMOTED THE MEIOTIC PROGRESSION OF MOUSE PRIMORDIAL GERM CELLS (PGCS)- DERIVED OOCYTE IN VITRO (2007) (0)
- Generation of pancreatic islet cells and progenitor cells from embryonic stem cells (2008) (0)
- Durable gene delivery to human epidermis in vivo Relative contributions of gene regulatory elements and stem cell targeting (1998) (0)
- WP-1 CANNABINOIDS INDUCE ANTIBODY CLASS SWITCHING IN CULTURES OF MOUSE (2007) (0)
- Increased Levels of Reactive Oxygen Species and Exhaustion of the Quiescent CD34+ Cells May Operate in Poor Graft Function after Allogeneic Hematopoietic Stem Cell Transplantation (2015) (0)
- Development of neutralizing monoclonal antibody against E2 protein of CSFV by using pseudovirus and pseudotyped virus. (2010) (0)
- Hypoxia Enhances the Differentiation of Hemogenic Endothelial Cells from Human Embryonic Stem Cells through Up-regulating Wnt5a Signal (2013) (0)
- Construction of symbiotic system of adult cells and early embryos (2009) (0)
- Enhancement of the in vivo persistence and antitumor efficacy of CD19 chimeric antigen receptor T cells through the delivery of modified TERT mRNA (2016) (0)
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What Schools Are Affiliated With Deng Hongkui?
Deng Hongkui is affiliated with the following schools:
