Denis Duboule | Academic Influence

Denis Duboule's AcademicInfluence.com Rankings

Denis Duboule

Biology

#903

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#1584

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Genetics

#158

World Rank

#197

Historical Rank

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Biology

Denis Duboule's Degrees

PhD Genetics University of Geneva
Bachelors Biology University of Geneva

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Why Is Denis Duboule Influential?

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According to Wikipedia, Denis Duboule is a Swiss-French biologist. He earned his PhD in Biology in 1984 and is currently Professor of Developmental Genetics and Genomics at the École polytechnique fédérale de Lausanne and at the Department of Genetics and Evolution of the University of Geneva. Since 2001, he is the Director of the Swiss National Research Center "Frontiers in Genetics" and since 2017, he is also a professor at the Collège de France. He has notably worked on Hox genes, a group of genes involved in the formation of the body plan and of the limbs.

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Denis Duboule's Published Works

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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

The Orphan Nuclear Receptor REV-ERBα Controls Circadian Transcription within the Positive Limb of the Mammalian Circadian Oscillator (2002) (2002)
The structural and functional organization of the murine HOX gene family resembles that of Drosophila homeotic genes. (1989) (877)
Coordinate expression of the murine Hox-5 complex homoeobox-containing genes during limb pattern formation (1989) (592)
Temporal colinearity and the phylotypic progression: a basis for the stability of a vertebrate Bauplan and the evolution of morphologies through heterochrony. (1994) (570)
Organizing Axes in Time and Space; 25 Years of Colinear Tinkering (2003) (529)
Early evolution of the venom system in lizards and snakes (2006) (506)
The rise and fall of Hox gene clusters (2007) (488)
Bone morphogenetic proteins and a signalling pathway that controls patterning in the developing chick limb. (1994) (476)
A Regulatory Archipelago Controls Hox Genes Transcription in Digits (2011) (476)
A Global Control Region Defines a Chromosomal Regulatory Landscape Containing the HoxD Cluster (2003) (472)
Topology of mammalian developmental enhancers and their regulatory landscapes (2013) (459)
Disruption of the Hoxd-13 gene induces localized heterochrony leading to mice with neotenic limbs (1993) (459)
Colinearity and functional hierarchy among genes of the homeotic complexes. (1994) (449)
Impaired skin wound healing in peroxisome proliferator–activated receptor (PPAR)α and PPARβ mutant mice (2001) (410)
The king cobra genome reveals dynamic gene evolution and adaptation in the snake venom system (2013) (401)
The king cobra genome reveals dynamic gene evolution and adaptation in the snake venom system (2013) (401)
The role of Hox genes during vertebrate limb development. (2007) (399)
A Switch Between Topological Domains Underlies HoxD Genes Collinearity in Mouse Limbs (2013) (387)
The Dynamic Architecture of Hox Gene Clusters (2011) (386)
Expression of the homeobox Hox-4 genes and the specification of position in chick wing development (1991) (385)
Of fingers, toes and penises (1997) (359)
Murine genes related to the Drosophila AbdB homeotic genes are sequentially expressed during development of the posterior part of the body. (1991) (345)
Guidebook to the homeobox genes (1994) (335)
Hox gene expression in teleost fins and the origin of vertebrate digits (1995) (318)
Targeted misexpression of Hox-4.6 in the avian limb bud causes apparent homeotic transformations (1992) (314)
Considerations when investigating lncRNA function in vivo (2014) (307)
Translating rodent behavioral repertoire to zebrafish (Danio rerio): Relevance for stress research (2010) (306)
Regional expression of the homeobox gene Nkx-2.2 in the developing mammalian forebrain (1992) (298)
Overexpression of BMP-2 and BMP-4 alters the size and shape of developing skeletal elements in the chick limb (1996) (294)
HOX-4 genes and the morphogenesis of mammalian genitalia. (1991) (288)
A Dual Role for Hox Genes in Limb Anterior-Posterior Asymmetry (2004) (286)
There is no highly conserved embryonic stage in the vertebrates: implications for current theories of evolution and development (1997) (281)
Measuring thigmotaxis in larval zebrafish (2012) (270)
A mouse gene related to Distal-less shows a restricted expression in the developing forebrain (1991) (264)
Multi-axial self-organization properties of mouse embryonic stem cells into gastruloids (2018) (264)
The Burmese python genome reveals the molecular basis for extreme adaptation in snakes (2013) (260)
Early developmental arrest of mammalian limbs lacking HoxA/HoxD gene function (2005) (259)
Spatially restricted domains of homeo-gene transcripts in mouse embryos: relation to a segmented body plan (1988) (246)
The loss of circadian PAR bZip transcription factors results in epilepsy. (2004) (240)
The evolution of 'bricolage'. (1998) (235)
Regulation of number and size of digits by posterior Hox genes: a dose-dependent mechanism with potential evolutionary implications. (1997) (235)
Structural and Functional Differences in the Long Non-Coding RNA Hotair in Mouse and Human (2011) (233)
Serial deletions and duplications suggest a mechanism for the collinearity of Hoxd genes in limbs (2002) (232)
Control of Hoxd genes' collinearity during early limb development. (2006) (231)
Gene Transpositions in the HoxD Complex Reveal a Hierarchy of Regulatory Controls (1996) (227)
Gene expression profiling of the long-term adaptive response to hypoxia in the gills of adult zebrafish. (2005) (222)
Localized and Transient Transcription of Hox Genes Suggests a Link between Patterning and the Segmentation Clock (2001) (212)
Zebrafish embryos and larvae: a new generation of disease models and drug screens. (2011) (210)
Synpolydactyly in mice with a targeted deficiency in the HoxD complex (1996) (206)
Mouse homeo-genes within a subfamily, Hox-1.4, -2.6 and -5.1, display similar anteroposterior domains of expression in the embryo, but show stage- and tissue-dependent differences in their regulation. (1989) (197)
The use of the zebrafish model in stress research (2011) (180)
Hox genes in digit development and evolution (1999) (180)
Function of posterior HoxD genes in the morphogenesis of the anal sphincter. (1996) (178)
The vertebrate limb: A model system to study the Hox/hom gene network during development and evolution (1992) (177)
Patterns of avoidance behaviours in the light/dark preference test in young juvenile zebrafish: A pharmacological study (2011) (174)
Two gene members of the murine HOX‐5 complex show regional and cell‐type specific expression in developing limbs and gonads. (1989) (173)
Large-Scale Assessment of the Zebrafish Embryo as a Possible Predictive Model in Toxicity Testing (2011) (173)
Engineering chromosomes in mice through targeted meiotic recombination (TAMERE) (1998) (172)
The segment‐specific gene Krox‐20 encodes a transcription factor with binding sites in the promoter region of the Hox‐1.4 gene. (1990) (171)
Discovery of a functional glucocorticoid receptor beta-isoform in zebrafish. (2008) (171)
Heterochrony and the phylotypic period. (1995) (171)
Expression of the murine Dlx-1 homeobox gene during facial, ocular and limb development. (1992) (167)
Vertebrate hox gene regulation: clustering and/or colinearity? (1998) (166)
Somite number and vertebrate evolution. (1998) (164)
Zebrafish development and regeneration: new tools for biomedical research. (2009) (161)
Modeling Hox gene regulation in digits: reverse collinearity and the molecular origin of thumbness. (2008) (160)
Changes in Hox genes’ structure and function during the evolution of the squamate body plan (2010) (155)
Inversion-induced disruption of the Hoxd cluster leads to the partition of regulatory landscapes (2005) (154)
Large scale transgenic and cluster deletion analysis of the HoxD complex separate an ancestral regulatory module from evolutionary innovations. (2001) (154)
Vertebrate evolution: the developmental origins of adult variation. (1999) (152)
Vertebrate Hox genes and proliferation: an alternative pathway to homeosis? (1995) (152)
Breaking Colinearity in the Mouse HoxD Complex (1999) (148)
Head-tail patterning of the vertebrate embryo: one, two or many unresolved problems? (2006) (146)
Mouse limb deformity mutations disrupt a global control region within the large regulatory landscape required for Gremlin expression. (2004) (145)
Evolutionary origin and development of snake fangs (2008) (144)
Embryonic timing, axial stem cells, chromatin dynamics, and the Hox clock (2017) (139)
Epigenetic Temporal Control of Mouse Hox Genes in Vivo (2009) (139)
Male accessory sex organ morphogenesis is altered by loss of function of Hoxd‐13 (1997) (138)
Hox-5.1 defines a homeobox-containing gene locus on mouse chromosome 2. (1988) (135)
Ulnaless (Ul), a regulatory mutation inducing both loss-of-function and gain-of-function of posterior Hoxd genes. (1997) (133)
The Hox-4.8 gene is localized at the 5′ extremity of the Hox-4 complex and is expressed in the most posterior parts of the body during development (1991) (133)
Conservation and Divergence of Regulatory Strategies at Hox Loci and the Origin of Tetrapod Digits (2014) (132)
Clustering of mammalian Hox genes with other H3K27me3 targets within an active nuclear domain (2015) (132)
Functional analysis of CTCF during mammalian limb development. (2010) (131)
Local alterations of Krox-20 and Hox gene expression in the hindbrain suggest lack of rhombomeres 4 and 5 in homozygote null Hoxa-1 (Hox-1.6) mutant embryos. (1993) (131)
Regulatory constraints in the evolution of the tetrapod limb anterior–posterior polarity (2006) (130)
Axial patterning in snakes and caecilians: evidence for an alternative interpretation of the Hox code. (2009) (126)
Haeckel's ABC of evolution and development (2002) (124)
HOX4 genes encode transcription factors with potential auto‐ and cross‐regulatory capacities. (1991) (121)
Temporal dynamics and developmental memory of 3D chromatin architecture at Hox gene loci (2014) (119)
Convergent evolution of complex regulatory landscapes and pleiotropy at Hox loci (2014) (119)
Development of the human pulmonary vein and its incorporation in the morphologically left atrium (2001) (119)
The HoxD cluster is a dynamic and resilient TAD boundary controlling the segregation of antagonistic regulatory landscapes (2017) (118)
A new technique for identifying sequence heterochrony. (2005) (116)
The origin of digits: expression patterns versus regulatory mechanisms. (2010) (116)
Deletion of a HoxD enhancer induces transcriptional heterochrony leading to transposition of the sacrum (1997) (115)
Homoeobox gene expression in mouse embryos varies with position by the primitive streak stage (1986) (113)
Patterning in the vertebrate limb. (1991) (113)
Large-Scale Analysis of Acute Ethanol Exposure in Zebrafish Development: A Critical Time Window and Resilience (2011) (109)
A mouse model for human short-stature syndromes identifies Shox2 as an upstream regulator of Runx2 during long-bone development. (2006) (107)
In vitro clonal analysis of progenitor cell patterns in dorsal root and sympathetic ganglia of the quail embryo. (1991) (107)
Transgenic analysis of Hoxd gene regulation during digit development. (2007) (106)
A new homeo‐box is present in overlapping cosmid clones which define the mouse Hox‐1 locus. (1986) (106)
How to make a limb? (1994) (105)
Attenuated sensing of SHH by Ptch1 underlies evolution of bovine limbs (2014) (105)
Mechanisms of Hox gene colinearity: transposition of the anterior Hoxb1 gene into the posterior HoxD complex. (2000) (104)
Homeobox genes and pattern formation in the vertebrate limb. (1992) (102)
In vivo targeted mutagenesis of a regulatory element required for positioning the Hoxd-11 and Hoxd-10 expression boundaries. (1996) (102)
Expression of the zebrafish gene hlx-1 in the prechordal plate and during CNS development. (1994) (102)
Uncoupling Time and Space in the Collinear Regulation of Hox Genes (2009) (102)
Comparative analysis of genes downstream of the Hoxd cluster in developing digits and external genitalia (2005) (101)
Hox‐1.6: a mouse homeo‐box‐containing gene member of the Hox‐1 complex. (1987) (99)
Forelimb-hindlimb developmental timing changes across tetrapod phylogeny (2007) (96)
Zebrafish embryos and larvae in behavioural assays (2012) (96)
Erratum: Corrigendum: The European dimension for the mouse genome mutagenesis program (2004) (95)
Teleost HoxD and HoxA genes: comparison with tetrapods and functional evolution of the HOXD complex (1996) (94)
Inverting the hourglass: quantitative evidence against the phylotypic stage in vertebrate development (2003) (93)
Behavioral profiling of zebrafish embryos exposed to a panel of 60 water-soluble compounds (2012) (92)
Zebrafish embryo development in a microfluidic flow-through system. (2011) (91)
Role of a polymorphism in a Hox/Pax-responsive enhancer in the evolution of the vertebrate spine (2013) (90)
Pluripotent neural crest cells in the developing skin of the quail embryo. (1993) (90)
Hotair Is Dispensible for Mouse Development (2016) (88)
Hox genes and the making of sphincters (1999) (87)
The mouse Hox-1.4 gene: primary structure, evidence for promoter activity and expression during development. (1989) (85)
Time, pattern, and heterochrony: a study of hyperphalangy in the dolphin embryo flipper (2002) (85)
Conservation of a functional hierarchy between mammalian and insect Hox/HOM genes. (1994) (84)
Exploratory behaviour in the open field test adapted for larval zebrafish: Impact of environmental complexity (2013) (84)
Developmental constraints in a comparative framework: a test case using variations in phalanx number during amniote evolution. (2003) (83)
Homeobox genes d11-d13 and a13 control mouse autopod cortical bone and joint formation. (2010) (83)
Analyzing developmental sequences within a phylogenetic framework. (2002) (82)
The mouse Hoxd13(spdh) mutation, a polyalanine expansion similar to human type II synpolydactyly (SPD), disrupts the function but not the expression of other Hoxd genes. (2001) (82)
Targeted inversion of a polar silencer within the HoxD complex re-allocates domains of enhancer sharing (2000) (81)
Structure and activity of regulatory elements involved in the activation of the Hoxd‐11 gene during late gastrulation. (1993) (80)
Analyzing evolutionary patterns in amniote embryonic development * (2002) (80)
Matrix metalloproteinases in osteoclasts of ontogenetic and regenerating zebrafish scales. (2011) (79)
Rostral and caudal pharyngeal arches share a common neural crest ground pattern (2009) (79)
Primary structure and embryonic expression pattern of the mouse Hox-4.3 homeobox gene. (1990) (78)
Chromatin organization and global regulation of Hox gene clusters (2013) (77)
A genetic approach to the transcriptional regulation of Hox gene clusters. (2011) (77)
Control of colinearity in AbdB genes of the mouse HoxD complex. (1998) (77)
Digit loss in archosaur evolution and the interplay between selection and constraints (2013) (76)
Distribution of pluripotent neural crest cells in the embryo and the role of brain-derived neurotrophic factor in the commitment to the primary sensory neuron lineage. (1993) (75)
A role for HOX13 proteins in the regulatory switch between TADs at the HoxD locus (2016) (74)
Hox gene function in vertebrate gut morphogenesis: the case of the caecum (2007) (72)
Duplications of hox gene clusters and the emergence of vertebrates. (2013) (72)
Nanoscale spatial organization of the HoxD gene cluster in distinct transcriptional states (2015) (72)
Multiple enhancers regulate Hoxd genes and the Hotdog LncRNA during cecum budding. (2013) (71)
Zebrafish Hoxa and Evx-2 genes: cloning, developmental expression and implications for the functional evolution of posterior Hox genes (1996) (71)
A molecular approach to the evolution of vertebrate paired appendages. (1996) (71)
From Haeckel to event-pairing: the evolution of developmental sequences (2002) (69)
Gene expression and digit homology in the chicken embryo wing (2005) (67)
Comparison of mouse and human HOX‐4 complexes defines conserved sequences involved in the regulation of Hox‐4.4. (1992) (65)
Epigenetic regulation of Hox gene activation: the waltz of methyls. (2008) (65)
A molecular genetic linkage map of mouse chromosome 2. (1990) (64)
Functional equivalence and rescue among group 11 Hox gene products in vertebral patterning. (1996) (63)
Is Sequence Heterochrony an Important Evolutionary Mechanism in Mammals? (2003) (62)
Differential expression of two different homeobox gene families during mouse tegument morphogenesis. (1994) (62)
Convergent evolution of pain-inducing defensive venom components in spitting cobras (2020) (61)
Epigenetic regulation of vertebrate Hox genes: A dynamic equilibrium (2009) (61)
A regulatory 'landscape effect' over the HoxD cluster. (2011) (60)
Septation and valvar formation in the outflow tract of the embryonic chick heart (2001) (60)
Heterochrony in limb evolution: developmental mechanisms and natural selection. (2009) (60)
Evolving Hox activity profiles govern diversity in locomotor systems. (2014) (59)
HoxD cluster scanning deletions identify multiple defects leading to paralysis in the mouse mutant Ironside. (2005) (56)
Interspecies exchange of a Hoxd enhancer in vivo induces premature transcription and anterior shift of the sacrum. (1997) (56)
Atypical relaxation of structural constraints in Hox gene clusters of the green anole lizard. (2009) (56)
Hox gene expression in limbs: colinearity by opposite regulatory controls. (1999) (56)
Snake Venom Gland Organoids (2020) (56)
Distinct Roles and Regulations for Hoxd Genes in Metanephric Kidney Development (2007) (54)
Tail Bud Progenitor Activity Relies on a Network Comprising Gdf11, Lin28, and Hox13 Genes. (2019) (53)
Limb development and evolution: a frog embryo with no apical ectodermal ridge (AER) (1998) (53)
Correlation of expression of Wnt-1 in developing limbs with abnormalities in growth and skeletal patterning (1993) (53)
後脳におけるKrox‐20およびHox遺伝子発現の局所的変更は同型配偶子ヌルHoxa‐1(Hox‐1.6)突然変異はいの菱脳の神経小片4および5の欠損を示唆する (1993) (52)
Mesoporous silica nanoparticles as a compound delivery system in zebrafish embryos (2012) (52)
Function of the Evx‐2 gene in the morphogenesis of vertebrate limbs. (1996) (52)
Interactions between HOXD and Gli3 genes control the limb apical ectodermal ridge via Fgf10. (2007) (51)
Developmental effects of cannabinoids on zebrafish larvae. (2013) (51)
A t(2;8) balanced translocation with breakpoints near the human HOXD complex causes mesomelic dysplasia and vertebral defects. (2002) (50)
Chromatin architectures and Hox gene collinearity. (2013) (50)
Developmental anatomy of lampreys (2010) (50)
Antagonists Go out on a Limb (1999) (50)
Limb development in a "nonmodel" vertebrate, the direct-developing frog Eleutherodactylus coqui. (2001) (49)
Global control regions and regulatory landscapes in vertebrate development and evolution. (2008) (49)
Developmental expression of the mouse Evx-2 gene: relationship with the evolution of the HOM/Hox complex. (1994) (48)
Ectopic nuclear reorganisation driven by a Hoxb1 transgene transposed into Hoxd (2008) (48)
Expression of Hox‐4 genes in the chick wing links pattern formation to the epithelial‐mesenchymal interactions that mediate growth. (1992) (47)
Dorso-ventral limb polarity and origin of the ridge: on the fringe of independence? (1997) (47)
The HOX-5 and surfeit gene clusters are linked in the proximal portion of mouse chromosome 2. (1990) (47)
Evolutionary conserved sequences are required for the insulation of the vertebrate Hoxd complex in neural cells (2002) (46)
Gene expression, polarising activity and skeletal patterning in reaggregated hind limb mesenchyme. (1995) (46)
Hox-4 gene expression in mouse/chicken heterospecific grafts of signalling regions to limb buds reveals similarities in patterning mechanisms. (1992) (45)
Diffusible gradients are out - an interview with Lewis Wolpert (2009) (45)
Historical Contingency in a Multigene Family Facilitates Adaptive Evolution of Toxin Resistance (2016) (45)
The organization of the murine HOX gene family resembles that of drosophila homeotic genes (1989) (45)
Landscapes and archipelagos: spatial organization of gene regulation in vertebrates. (2012) (44)
Noncoding copy-number variations are associated with congenital limb malformation (2017) (44)
Additive and global functions of HoxA cluster genes in mesoderm derivatives. (2010) (43)
The neural crest population responding to endothelin-3 in vitro includes multipotent cells. (1997) (43)
Structure, function and evolution of topologically associating domains (TADs) atHOX loci (2015) (43)
Misexpression of noggin leads to septal defects in the outflow tract of the chick heart. (2001) (42)
Genetic analysis of a conserved sequence in the HoxD complex: Regulatory redundancy or limitations of the transgenic approach? (1998) (40)
An update of mouse and human HOX gene nomenclature. (1990) (40)
The Evolution of Fangs, Venom, and Mimicry Systems in Blenny Fishes (2017) (39)
The mis-expression of posterior Hox-4 genes in talpid (ta3) mutant wings correlates with the absence of anteroposterior polarity. (1992) (39)
Evolution and Development of Ventricular Septation in the Amniote Heart (2014) (37)
Developmental transformations in a normal series of embryos of the sea lamprey Petromyzon marinus (linnaeus) (2003) (37)
Genetic analysis of a Hoxd-12 regulatory element reveals global versus local modes of controls in the HoxD complex. (1998) (36)
Comparative methods in developmental biology. (2001) (36)
Impact of copy number variations (CNVs) on long-range gene regulation at the HoxD locus (2012) (36)
Teratological effects of a panel of sixty water-soluble toxicants on zebrafish development. (2014) (35)
The regulatory landscapes of developmental genes (2020) (34)
Proximodistal patterning of the limb: insights from evolutionary morphology (2004) (33)
Polymorphism in developmental timing: intraspecific heterochrony in a Lake Victoria cichlid (2009) (33)
DNA sequences homologous to the Drosophila opa repeat are present in murine mRNAs that are differentially expressed in fetuses and adult tissues (1987) (33)
Transgenic analysis of a potential Hoxd-11 limb regulatory element present in tetrapods and fish. (1996) (33)
A Genetic Approach to the Recruitment of PRC2 at the HoxD Locus (2013) (32)
The constrained architecture of mammalian Hox gene clusters (2019) (32)
Hox is in the hair: a break in colinearity? (1998) (32)
Classification of limb defects. (1998) (32)
Circumventing the polydactyly ‘constraint’: the mole's ‘thumb’ (2012) (31)
Genotypic Features of Lentivirus Transgenic Mice (2008) (31)
A treasure house of comparative embryology. (1999) (30)
Relationship in the chick of the developing pulmonary vein to the embryonic systemic venous sinus (2000) (29)
Snake Genome Sequencing: Results and Future Prospects (2016) (29)
Control of Hoxd gene transcription in the mammary bud by hijacking a preexisting regulatory landscape (2016) (29)
Large scale genomic reorganization of topological domains at the HoxD locus (2017) (29)
A Systematic Enhancer Screen Using Lentivector Transgenesis Identifies Conserved and Non-Conserved Functional Elements at the Olig1 and Olig2 Locus (2010) (28)
Osteoclast-like Cells in Early Zebrafish Embryos (2014) (28)
Chromatin topology and the timing of enhancer function at the HoxD locus (2020) (28)
Reorganisation of Hoxd regulatory landscapes during the evolution of a snake-like body plan (2016) (28)
Phylotypic stage theory. (1998) (28)
Genomic annotation and transcriptome analysis of the zebrafish (Danio rerio) hox complex with description of a novel member, hoxb13a (2005) (28)
Topological Domains, Metagenes, and the Emergence of Pleiotropic Regulations at Hox Loci. (2016) (27)
Pattern formation today. (2009) (27)
Some problems with typological thinking in evolution and development (1999) (26)
An enhancer-titration effect induces digit-specific regulatory alleles of the HoxD cluster. (2003) (26)
Reconstruction from serial sections: A tool for developmental biology. Application to Hox genes expression in chicken wing buds (1993) (24)
Outflow tract septation and the aortic arch system in reptiles: lessons for understanding the mammalian heart (2017) (24)
Time for Chronomics? (2003) (24)
Mechanisms of pigment pattern formation in the quail embryo (1990) (23)
Characterization of mouse Dactylaplasia mutations: a model for human ectrodactyly SHFM3 (2008) (23)
A function for all posterior Hoxd genes during digit development? (2012) (23)
Combined function of HoxA and HoxB clusters in neural crest cells. (2013) (22)
Bimodal control of Hoxd gene transcription in the spinal cord defines two regulatory subclusters (2012) (22)
SnapShot: Hox Gene Regulation (2014) (22)
Visualizing the HoxD Gene Cluster at the Nanoscale Level. (2015) (22)
Viral enhancer activity in teratocarcinoma cells. (1985) (22)
A phylotypic stage for all animals? (2012) (22)
Developmental genetics: A Hox by any other name (2000) (22)
Integration of Shh and Fgf signaling in controlling Hox gene expression in cultured limb cells (2017) (21)
The murine genes Hox-5.1 and Hox-4.1 belong to the same HOX complex on chromosome 2. (1990) (21)
Sequencing and genomic annotation of the chicken (Gallus gallus) Hox clusters, and mapping of evolutionarily conserved regions (2007) (21)
Pigment patterns in neural crest chimeras constructed from quail and guinea fowl embryos. (1991) (21)
Developmental biology: Serpent clocks tick faster (2008) (21)
Colinearity loops out. (2004) (20)
Hox genes and the morphogenesis of the vertebrate limb. (1993) (20)
Similarities and differences in the regulation of HoxD genes during chick and mouse limb development (2018) (19)
A question of intent: when is a 'schematic' illustration a fraud? (2001) (19)
The function of Hox genes in the morphogenesis of the vertebrate limb. (1993) (19)
Beyond organoids: In vitro vasculogenesis and angiogenesis using cells from mammals and zebrafish. (2017) (19)
A complex regulatory landscape involved in the development of mammalian external genitals (2020) (19)
Generating Gastruloids from Mouse Embryonic Stem Cells (2018) (18)
Heterogeneous combinatorial expression of Hoxd genes in single cells during limb development (2018) (18)
Extended embryo retention, caecilian oviparity and amniote origins (2002) (18)
Heterochrony and Early Left-Right Asymmetry in the Development of the Cardiorespiratory System of Snakes (2015) (17)
Developmental stages until hatching of the Lake Victoria cichlid Haplochromis piceatus (Teleostei: Cichlidae) (2009) (17)
Chromatin looping and organization at developmentally regulated gene loci (2013) (17)
Pigment pattern expression in the plumage of the quail embryo and the quail-chick chimaera (1989) (17)
Impact of genome architecture on the functional activation and repression of Hox regulatory landscapes (2019) (16)
Control of growth and gut maturation by HoxD genes and the associated lncRNA Haglr (2017) (16)
Transcriptional heterochrony in talpid mole autopods (2012) (16)
A fine analysis of glucose-phosphate-isomerase patterns in single preimplantation mouse embryos. (1985) (16)
The Art of Making a Joint (2001) (16)
Mammalian-specific ectodermal enhancers control the expression of Hoxc genes in developing nails and hair follicles (2020) (15)
Functional characterization of the cannabinoid receptors 1 and 2 in zebrafish larvae using behavioral analysis (2019) (15)
Reshuffling genomic landscapes to study the regulatory evolution of Hox gene clusters (2011) (14)
Sequential in cis mutagenesis in vivo reveals various functions for CTCF sites at the mouse HoxD cluster (2021) (14)
Developmental biology: Hotspots for evolution (2003) (14)
The Orphan Nuclear Receptor REVERB Controls Circadian Transcription within the Positive Limb of the Mammalian Circadian Oscillator of the hypothalamus (2002) (14)
The evo‐devo comet (2010) (14)
The Evolution of Genomics (1997) (13)
Tracing microRNA patterns in mice (2004) (13)
Contents (2015) (13)
Tetrapod axial evolution and developmental constraints; Empirical underpinning by a mouse model (2015) (13)
What does the human embryo look like, and does it matter? (1999) (13)
Conserved elements within open reading frames of mammalian Hox genes (2009) (12)
Structural and functional aspects of mammalian Hox genes (1993) (12)
Widespread Evolution of Molecular Resistance to Snake Venom α-Neurotoxins in Vertebrates (2020) (12)
Analysis of the dynamics of limb transcriptomes during mouse development (2011) (12)
No milk today (my Hox have gone away). (1999) (12)
Murine Homeo-Genes: Some Aspects of their Organisation and Structure (1989) (12)
The Light–Dark Preference Test for Larval Zebrafish (2012) (12)
The murine even-skipped-like gene Evx-2 is closely linked to the Hox-4 complex, but is transcribed in the opposite direction (2004) (11)
Dynamic genetic differentiation drives the widespread structural and functional convergent evolution of snake venom proteinaceous toxins (2022) (11)
Genetic control of murine limb morphogenesis Relationships with human syndromes and evolutionary relevance (1998) (11)
Analysis of Cardiac Development in the Turtle Emys orbicularis (Testudines: Emidydae) using 3‐D Computer Modeling from Histological Sections (2010) (11)
Developmental biology: Making progress with limb models (2002) (11)
Derivation of snake venom gland organoids for in vitro venom production (2021) (10)
Snakes: hatching of a model system for Evo-Devo? (2014) (10)
Metabolic effects of cannabinoids in zebrafish (Danio rerio) embryos determined by 1H NMR metabolomics (2016) (10)
Dbx2 regulation in limbs suggests interTAD sharing of enhancers (2021) (10)
The Hox Complex - an interview with Denis Duboule (2009) (10)
Combining Motion Analysis and Microfluidics – A Novel Approach for Detecting Whole-Animal Responses to Test Substances (2014) (10)
Local alterations of Krox-20 and Hox gene expression in the hindbrain suggest loss of rhombomeres 4 (1993) (10)
Developmental biology in Geneva: a three century-long tradition. (2002) (10)
Developmental biology: Reproduction in clusters (2005) (10)
Analysis of Polycerate Mutants Reveals the Evolutionary Co-option of HOXD1 for Horn Patterning in Bovidae (2021) (9)
A nested deletion approach to generate Cre deleter mice with progressive Hox profiles. (2002) (9)
Generation and characterization of monoclonal antibodies to the neural crest. (2001) (9)
Humerus development in moles (Talpidae, Mammalia) (2014) (8)
Essay the (unusual) heuristic value of Hox gene clusters; a matter of time? (2022) (8)
The Burmese python genome reveals the molecular basis for extreme adaptation in snakes (Proceedings of the National Academy of Sciences of the United States of America (2013) 110, 51, (20645-20650) DOI: 10.1073/pnas. 1314475110) (2014) (8)
Mesomelic dysplasias associated with the HOXD locus are caused by regulatory reallocations (2021) (8)
Zebrafish as a Model for Systems Medicine R&D: Rethinking the Metabolic Effects of Carrier Solvents and Culture Buffers Determined by (1)H NMR Metabolomics. (2016) (8)
Detection and identification of antibacterial proteins in snake venoms using at-line nanofractionation coupled to LC-MS. (2018) (7)
Characterization of paralogous uncx transcription factor encoding genes in zebrafish (2019) (7)
Time‐sequenced transcriptomes of developing distal mouse limb buds: A comparative tissue layer analysis (2021) (7)
New directions in comparative embryology and the nature of developmental characters (2003) (7)
Methods to Quantify Basal and Stress-Induced Cortisol Response in Larval Zebrafish (2012) (7)
Transgene- and locus-dependent imprinting reveals allele-specific chromosome conformations (2013) (7)
Haeckel's Embryos, Continued (1998) (7)
The genetics of murine Hox loci: TAMERE, STRING, and PANTHERE to engineer chromosome variants. (2014) (7)
Morphology of the distal tip of the upper mandible of the ostrich (Struthio camelus) embryo during hatching. (1998) (7)
Transcriptome annotation and characterization of novel toxins in six scorpion species (2019) (7)
Theories, laws, and models in evo‐devo (2021) (7)
Cooperation of regulatory elements involved in the activation of the Hoxd-11 gene. (1993) (6)
Tissue preference and differentiation of malignant rat x mouse hybrid cells in chimaeric mouse fetuses. (1982) (6)
Tinkering with constraints in the evolution of the vertebrate limb anterior-posterior polarity. (2007) (6)
Molecular tools, classic questions: an interview with Clifford Tabin (2009) (6)
Convergent evolution of toxin resistance in animals (2022) (6)
Assessment of Thigmotaxis in Larval Zebrafish (2012) (6)
Ventricular Septation and Outflow Tract Development in Crocodilians Result in Two Aortas with Bicuspid Semilunar Valves (2021) (5)
Fryns type mesomelic dysplasia of the upper limbs caused by inverted duplications of the HOXD gene cluster (2019) (5)
18 Muscle and tendon pattern is altered independently of skeletal pattern in HoxD mutant limbs. (2002) (5)
A Genetic Basis for Altered Sexual Behavior in Mutant Female Mice (2012) (5)
Frequent Episode Mining to Support Pattern Analysis in Developmental Biology (2010) (5)
Haeckel's Embryos (1998) (5)
In vitro development of zebrafish vascular networks. (2017) (5)
The sonic hedgehog signaling pathway and the development of pharyngeal arch Derivatives in Haplochromis piceatus, a Lake Victoria cichlid (2015) (5)
Induction of a chromatin boundary in vivo upon insertion of a TAD border (2021) (5)
Editorial: Haeckel and modern biology (2002) (5)
Comparative transcriptome analyses of venom glands from three scorpionfishes. (2019) (4)
Assessing Teratogenicity from the Clustering of Abnormal Phenotypes in Individual Zebrafish Larvae. (2016) (4)
Sequential And Directional Insulation By Conserved CTCF Sites Underlies The Hox Timer In Pseudo-Embryos (2022) (4)
From Clone to Bone: Manus horribilis : the chicken wing skeleton (2012) (4)
Hox genes and the molecular bases of vertebrate limb pattern formation (1992) (4)
Protein synthesis in hybrid cells derived from fetal rat x mouse chimeric organs. (1982) (4)
S05-03. Epigenetic control of hox genes collinear activation during vertebrate development (2009) (4)
[Hox genes and genetic control of limb development]. (1997) (4)
A naturalist's evo-devo (2003) (4)
The Evolution of Fangs, Venom, and Mimicry Systems in Blenny Fishes (2017) (4)
Considerations when investigating lncRNA function (2014) (4)
Effect of pesticides and metals on zebrafish embryo development and larval locomotor activity (2020) (3)
Differentiation and gene regulation. (2007) (3)
Normal stages of embryonic development of a brood parasite, the rosy bitterling Rhodeus ocellatus (Teleostei: Cypriniformes) (2020) (3)
Context-dependent enhancer function revealed by targeted inter-TAD relocation (2022) (3)
A Complex Regulatory Landscape Involved In The Development Of External Genitals (2019) (3)
Behavioral effects of cannabinoids on zebrafish larvae (2012) (3)
From Clone to Bone: A molecular–morphological study of a peculiar limb morphology: the development and evolution of the mole's ‘thumb’ (2012) (3)
Regeneration and pattern formation - an interview with Susan Bryant (2009) (3)
Preface to pattern formation special issue. (2009) (2)
A non-lethal method for studying scorpion venom gland transcriptomes, with a review of potentially suitable taxa to which it can be applied (2021) (2)
PHYSICAL MAPPING OF THE X-LINKED CLEFT-PALATE LOCUS (1994) (2)
Selection on Phalanx Development in the Evolution of the Bird Wing (2021) (2)
The revolutionary developmental biology of Wilhelm His, Sr. (2022) (2)
Developmental and evolutionary comparative analysis of a regulatory landscape in mouse and chicken (2022) (2)
Ectopic Expression of Wnt-1 Induces Abnormalities in Growth and Skeletal Patterning of the Limbs (1995) (2)
Molecular Genetic Analysis of the Role of the HoxD Complex in Skeletal Development (2004) (2)
Response to Peron et al. (2018) (2)
[Genetic control of limb development]. (1996) (2)
The Hox complex - an interview with Denis Duboule. Interviewed by Richardson, Michael K. (2009) (2)
Impact of genome architecture on the functional activation and repression of Hox regulatory landscapes (2019) (2)
HOX13-MEDIATED DBX2 REGULATION IN LIMBS SUGGESTS INTER-TAD SHARING OF ENHANCERS (2020) (1)
A comparison of the expression domains of the murine HOX-4, RARs and CRABP genes suggests possible functional relationships during patterning of the vertebrate limb (1991) (1)
CONTEXT-INDEPENDENT FUNCTION OF A CHROMATIN BOUNDARY IN VIVO (2021) (1)
Role of Hoxc genes in the development of the limb integumentary organ (nail, claw, or hoof) (2018) (1)
SPECIFIC ECTODERMAL ENHANCERS CONTROL THE EXPRESSION OF Hoxc GENES IN DEVELOPING MAMMALIAN INTEGUMENTS (2020) (1)
Single-cell mRNA profiling reveals heterogeneous combinatorial expression of Hoxd genes during limb development (2018) (1)
Faculty Opinions recommendation of Silencing of Smed-betacatenin1 generates radial-like hypercephalized planarians. (2008) (1)
A dynamic equilibrium (2009) (1)
49. The Origin and Evolution of Metalloproteinases in the Venom of Snakes (2012) (1)
Wilhelm His Sr. and the development of paraffin embedding (2021) (1)
The Epicardium in Ventricular Septation During Evolution and Development (2016) (1)
Author response: A complex regulatory landscape involved in the development of mammalian external genitals (2020) (1)
Limb-fin heterochrony: a case study analysis of molecular and morphological characters using frequent episode mining (2007) (1)
A Long and Winding Road (2005) (1)
Preface to the symposium "Trends in the Evolution of Amniote Embryos". (2009) (1)
Cyclic transcription of Hox genes suggests a link between patterning and the segmentation clock (2001) (1)
Author response: Reorganisation of Hoxd regulatory landscapes during the evolution of a snake-like body plan (2016) (1)
Explorer Considerations when investigating lncRNA function in vivo (2014) (1)
Quail neural crest cells cannot read positional values in the dorsal trunk feathers of the chicken embryo (1991) (1)
HOX-4 genes, retinoic acid and the specification of positional information during chick wing morphogenesis (1992) (1)
Transcriptional heterochrony in talpid mole autopods (2012) (1)
DEVELOPMENTAL AND EVOLUTIONARY COMPARATIVE ANALYSIS OF A REGULATORY LANDSCAPE IN MAMMALS AND BIRDS (2021) (1)
[Wilhelm His, Sr., and the development of paraffin embedding. German version]. (2021) (1)
Author response: Temporal dynamics and developmental memory of 3D chromatin architecture at Hox gene loci (2014) (1)
Author response: Considerations when investigating lncRNA function in vivo (2014) (0)
Nanoplastics causes extensive congenital malformations during embryonic development by passively targeting neural crest cells. (2023) (0)
Transcriptome annotation and characterization of novel toxins in six scorpion species (2019) (0)
Zebrafish embryos and larvae as a complementary model for behavioural research (2014) (0)
Overview of 3D reconstructions comparing similar developmental stages (Zehr 32–33 (2015) (0)
Overview of 3D reconstructions comparing similar developmental stages (Zehr 25–28 (2015) (0)
Eye-Transcriptome and Genome-Wide Sequencing for Scolecophidia: Implications for Inferring the Visual System of the Ancestral Snake (2021) (0)
Editorial Board (1995) (0)
chr2 of mutant genomes used in Rodriguez-Carballo et al. 2020 (2020) (0)
Outflow tract septation and the aortic arch system in reptiles: lessons for understanding the mammalian heart (2017) (0)
Ernst Hafen: a sized controlled career (2004) (0)
Conferences and courses (2008) (0)
The Hox-4 genes and the molecular bases of pattern formation (1991) (0)
The Eunectus notaeus heart (ID BS8). (2015) (0)
Molecular tools, classic questions - (2009) (0)
Metabolic effects of carrier solvents and culture buffers in zebrafish embryos determined by 1 H NMR metabolomics. (2013) (0)
Antagonists Go out on a Limb Minireview (1999) (0)
New insights into the functional role of Hoxc genes in the limb ectoderm (2017) (0)
Development and regulation of the venom-delivery system in snakes (2008) (0)
Pushing the frontiers of development (2008) (0)
Comparison ofmouse andhumanHOX-4complexes defines conserved sequencesinvolved intheregulation (1992) (0)
Developmental mechanisms of body plan evolution in a morphocline of salamanders (2008) (0)
Hox genes and limb morphogenesis (2007) (0)
The growth of endothelial-like cells in zebrafish embryoid body culture. (2020) (0)
Analysis of Polycerate Mutants Reveals the Evolutionary Co-option of HOXD1 to Determine the Number and Topology of Horns in Bovidae (2020) (0)
22-P021 Long-range enhancer–promoter interactions in the HoxD complex (2009) (0)
Tissue preference and differentiation of malignant hybrid cells during mouse development. Abstr. (1980) (0)
New methods for determining heterochronic change (2003) (0)
Snake specimens used here to study snake lungs and pulmonary artery anatomy and the associated results. (2015) (0)
the green anole lizard gene clusters of Hox Atypical relaxation of structural constraints in (2009) (0)
Faculty Opinions recommendation of The role of chromatin structure in regulating the expression of clustered genes. (2005) (0)
Evo-devo and genomics of snakes. (2020) (0)
Nanoscale Spatial Organization of Chromatin in its Cellular Context, from Telomeres to Hox (2016) (0)
Constrained Transcriptional Polarity in the Organization of Mammalian Hox Gene Clusters (2019) (0)
Targeted deficiency in the mouse HoxD complex: compound digit defects as a model for the human synpolydactyly syndrome (1998) (0)
Hox Genes Regulation During Vertebrate Development and Evolution (2017) (0)
Conservation and Variations of Bimodal HoxD Gene Regulation During Tetrapod Limb Development (2018) (0)
an interview with Susan Bryant (2009) (0)
LINKAGE ANALYSIS OF X-LINKED CLEFT-PALATE IN AN ICELANDIC PEDIGREE (1993) (0)
53. Evolutionary Expansion of Venom Genes in the King Cobra Genome (2012) (0)
Supplementary Material for: Sequencing and genomic annotation of the chicken (Gallus gallus) Hox clusters, and mapping of evolutionarily conserved regions (2017) (0)
Molecular adaptation and resistance, to the Α-neurotoxin of elapid snakes, in Squamata, aves and fishes. (2020) (0)
Classification of observed pulmonary artery anatomies. (2015) (0)
Passive Targeting of Neural Crest Cells by Nanoplastics Causes Extensive Congenital Malformations During Embryonic Development (2023) (0)
Author response for "Theories, laws, and models in evo‐devo" (2021) (0)
Metabolic effects of cannabinoids in zebrafish (Danio rerio) embryos determined by 1H NMR metabolomics (2016) (0)
Large scale genomic reorganization of topological domains at the HoxD locus (2017) (0)
Heterochrony , ontogenetic repatterning , and the evolution of direct development in caecilian amphibians (2007) (0)
Targeted Meiotic Recombination (TAMERE) (2002) (0)
The sequence of the chicken HOX gene clusters: Identification of conserved regulatory regions through comparative genomics (2005) (0)
Dynamic genetic differentiation drives the widespread structural and functional convergent evolution of snake venom proteinaceous toxins (2022) (0)
Alterations in Ptch1 Cis-Regulation underlie loss of antero-posterior identity and digit reductions in bovine limbs (2013) (0)
Faculty Opinions recommendation of Toward simpler and faster genome-wide mutagenesis in mice. (2007) (0)
Synthetic Biology and Genomics Platform for New-to-Nature Bioactive Peptides (2014) (0)
Author Correction: EMPReSS: standardized phenotype screens for functional annotation of the mouse genome (2022) (0)
Functional Characterization of Gene Regulatory Elements of Epilepsy-Associated Genes (2015) (0)
Legend for 3D segmentations in Amira. (2015) (0)
Evolutionary developmental biology of bitterling fish (2022) (0)
Genetic manipulation of the mammalian embryo: results and prospects (1984) (0)
A genetic approach of long-range gene regulation during development and evolution (2016) (0)
Lentiviral vectors mediated transgenesis (2011) (0)
Multi-axial self-organization properties of mouse embryonic stem cells into gastruloids (2018) (0)
BDRA Reviewer Thank You 2015. (2016) (0)
Regulation and function of vertebrate Hox genes during limb development and evolution (1997) (0)
Characterization of paralogous uncx transcription factor encoding genes in zebrafish. (2019) (0)
Genes controlling development in mammals. (1990) (0)
Heterogeneous combinatorial expression of Hoxd genes in single cells during limb development (2018) (0)
High-throughput analysis of proximo-distal transcriptional profiles in limb development (2016) (0)
No milk today (my Hox have gone (2016) (0)
Commentary on paper by Leroy C. (2019) (0)
15-P011 A typical relaxation of structural constraints in Hox gene clusters of squamates (2009) (0)
Response to Peron et al. (2018) (0)
[Control of limb morphogenesis by the Hox genes]. (1997) (0)
Collinearity in Mouse Limbs Genes HoxD A Switch Between Topological Domains Underlies (2014) (0)
Limb morphogenesis and evolution: The molecular genetics approach (2000) (0)
09-P102 Somitogenesis and development of primary motor neurons: The role of the homeobox uncx4.1 (2009) (0)
Rescue of an aggressive female sexual courtship in mice by CRISPR/Cas9 secondary mutation in vivo (2018) (0)
Shifts in axial patterning in snake and caecilian embryos (2009) (0)
Hoxc genes play a central role in claw/nail development (2019) (0)
From buds to paws, a temporal transcriptome analysis (2016) (0)
Denis Duboule the green anole lizard gene clusters of Hox Atypical relaxation of structural constraints in Material (2009) (0)
[A STRING lifts the veil on the mechanisms controlling Hox genes expression]. (2006) (0)
Chapter 2---------------------------------------------- Zebrafish embryos and larvae in behavioural assays (2014) (0)
The Axial Level of the Heart in Snakes (2016) (0)
Adaptation to hypoxia in embryos of zebrafish and Lake Victoria cichlids (2002) (0)
The Hox Complex (2009) (0)
Rescue of an aggressive female sexual courtship in mice by CRISPR/Cas9 secondary mutation in vivo (2017) (0)
Cichlid developmental phylogenetics (2007) (0)
Inter-guild differences and possible causes to the recovery of cichlid (2004) (0)
Large-Scale Genomic Reorganizations of Topological Domains (TADs) at the HoxD Locus (2017) (0)
Homeobox genes and mouse skin regionalization (1995) (0)
Developmental neuroanatomy of the rosy bitterling Rhodeus ocellatus (Teleostei: Cypriniformes)—A microCT study (2021) (0)
Genetic cold cases: lessons from solving complex congenital limb disorders (2023) (0)
A systematic enhancer screen using lentivector transgenesis identifies conserved and non-conserved functional elements at the Olig 1 and Olig 2 locus FRIEDLI (2017) (0)

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