Denisa D Wagner
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Researcher ORCID ID = 0000-0002-4494-413X
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Biology
Denisa D Wagner's Degrees
- Masters Biochemistry Stanford University
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(Suggest an Edit or Addition)Denisa D Wagner's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Extracellular DNA traps promote thrombosis (2010) (1866)
- Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo (2012) (1387)
- Leukocyte rolling and extravasation are severely compromised in P selectin-deficient mice (1993) (1107)
- PADGEM protein: A receptor that mediates the interaction of activated platelets with neutrophils and monocytes (1989) (895)
- CD40L stabilizes arterial thrombi by a β3 integrin–dependent mechanism (2002) (770)
- Neutrophil extracellular traps promote deep vein thrombosis in mice (2012) (750)
- Immunolocalization of von Willebrand protein in Weibel-Palade bodies of human endothelial cells (1982) (707)
- Diabetes primes neutrophils to undergo NETosis, which impairs wound healing (2015) (698)
- Cancers predispose neutrophils to release extracellular DNA traps that contribute to cancer-associated thrombosis (2012) (649)
- Cell biology of von Willebrand factor. (1990) (638)
- Thrombosis: tangled up in NETs. (2014) (624)
- Dynamic Visualization of Thrombopoiesis Within Bone Marrow (2007) (621)
- Targeted disruption of cd39/ATP diphosphohydrolase results in disordered hemostasis and thromboregulation (1999) (555)
- Platelets in Inflammation and Thrombosis (2003) (544)
- Susceptibility to Infection and Altered Hematopoiesis in Mice Deficient in Both P- and E-Selectins (1996) (540)
- PADGEM (GMP140) is a component of Weibel-Palade bodies of human endothelial cells. (1989) (540)
- A mouse model of severe von Willebrand disease: defects in hemostasis and thrombosis. (1998) (531)
- Persistence of platelet thrombus formation in arterioles of mice lacking both von Willebrand factor and fibrinogen. (2000) (506)
- Platelets roll on stimulated endothelium in vivo: an interaction mediated by endothelial P-selectin. (1995) (506)
- The combined role of P- and E-selectins in atherosclerosis. (1998) (487)
- Hematopoietic Progenitor Cell Rolling in Bone Marrow Microvessels: Parallel Contributions by Endothelial Selectins and Vascular Cell Adhesion Molecule 1 (1998) (472)
- Inducible secretion of large, biologically potent von Willebrand factor multimers (1986) (456)
- Neutrophil extracellular trap (NET) impact on deep vein thrombosis. (2012) (451)
- Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation (2015) (438)
- P-Selectin Glycoprotein Ligand 1 (Psgl-1) Is Expressed on Platelets and Can Mediate Platelet–Endothelial Interactions in Vivo (2000) (432)
- Nitric Oxide Regulates Exocytosis by S-Nitrosylation of N-ethylmaleimide-Sensitive Factor (2003) (431)
- Shear-Activated Nanotherapeutics for Drug Targeting to Obstructed Blood Vessels (2012) (423)
- Neutrophil histone modification by peptidylarginine deiminase 4 is critical for deep vein thrombosis in mice (2013) (411)
- CalDAG-GEFI integrates signaling for platelet aggregation and thrombus formation (2004) (405)
- Platelet P-selectin facilitates atherosclerotic lesion development. (2003) (403)
- Endothelial selectins and vascular cell adhesion molecule-1 promote hematopoietic progenitor homing to bone marrow. (1998) (401)
- The Clearance Mechanism of Chilled Blood Platelets (2003) (384)
- von Willebrand factor-mediated platelet adhesion is critical for deep vein thrombosis in mouse models. (2011) (374)
- The A2B adenosine receptor protects against inflammation and excessive vascular adhesion. (2006) (356)
- Histones induce rapid and profound thrombocytopenia in mice. (2011) (355)
- Platelets and platelet adhesion support angiogenesis while preventing excessive hemorrhage. (2006) (348)
- PADGEM-dependent adhesion of platelets to monocytes and neutrophils is mediated by a lineage-specific carbohydrate, LNF III (CD15) (1990) (346)
- Selectins: A family of adhesion receptors (1991) (338)
- Adhesion molecules--Part 1. (1996) (332)
- Elevated Levels of Circulating DNA and Chromatin Are Independently Associated With Severe Coronary Atherosclerosis and a Prothrombotic State (2013) (331)
- The vessel wall and its interactions. (2008) (328)
- Shigatoxin triggers thrombotic thrombocytopenic purpura in genetically susceptible ADAMTS13-deficient mice. (2005) (326)
- Platelets adhere to and translocate on von Willebrand factor presented by endothelium in stimulated veins. (2000) (320)
- P-selectin promotes neutrophil extracellular trap formation in mice. (2015) (318)
- Pro-coagulant state resulting from high levels of soluble P-selectin in blood. (2000) (310)
- Interaction of P-selectin and PSGL-1 generates microparticles that correct hemostasis in a mouse model of hemophilia A (2003) (301)
- The P‐selectin, tissue factor, coagulation triad (2005) (300)
- Adhesion molecules--Part II: Blood vessels and blood cells. (1996) (297)
- Biosynthesis of von Willebrand protein by human endothelial cells: processing steps and their intracellular localization (1984) (290)
- Hypoxia-induced exocytosis of endothelial cell Weibel-Palade bodies. A mechanism for rapid neutrophil recruitment after cardiac preservation. (1996) (287)
- The Weibel-Palade Body: the Storage Granule for von Willebrand Factor and P-selectin (1993) (280)
- Prominent role of P-selectin in the development of advanced atherosclerosis in ApoE-deficient mice. (2000) (269)
- Induction of specific storage organelles by von Willebrand factor propolypeptide (1991) (268)
- P-Selectin and platelet clearance. (1998) (266)
- Extracellular DNA traps are associated with the pathogenesis of TRALI in humans and mice. (2011) (266)
- Heme-induced neutrophil extracellular traps contribute to the pathogenesis of sickle cell disease. (2014) (265)
- Biosynthesis of von Willebrand protein by human megakaryocytes. (1985) (262)
- Absence of P-selectin delays fatty streak formation in mice. (1997) (255)
- Increased neutrophil extracellular trap formation promotes thrombosis in myeloproliferative neoplasms (2018) (255)
- Platelet serotonin promotes the recruitment of neutrophils to sites of acute inflammation in mice. (2013) (255)
- Circulating DNA and myeloperoxidase indicate disease activity in patients with thrombotic microangiopathies. (2012) (238)
- von Willebrand factor-cleaving protease ADAMTS13 reduces ischemic brain injury in experimental stroke. (2009) (237)
- How platelets safeguard vascular integrity (2011) (232)
- Multiple, targeted deficiencies in selectins reveal a predominant role for P-selectin in leukocyte recruitment. (1999) (230)
- Systemic antithrombotic effects of ADAMTS13 (2006) (227)
- Vicinal cysteines in the prosequence play a role in von Willebrand factor multimer assembly. (1992) (226)
- Plasma fibronectin promotes thrombus growth and stability in injured arterioles (2003) (223)
- P-selectin and leukocyte microparticles are associated with venous thrombogenesis. (2003) (221)
- Defects in hemostasis in P-selectin-deficient mice. (1996) (209)
- Platelet-endothelial interactions in inflamed mesenteric venules. (1998) (206)
- Neutrophil extracellular traps form predominantly during the organizing stage of human venous thromboembolism development (2014) (204)
- Activated platelets induce Weibel-Palade-body secretion and leukocyte rolling in vivo: role of P-selectin. (2005) (203)
- Tumor Necrosis Factor-&agr;-Converting Enzyme (ADAM17) Mediates GPIb&agr; Shedding From Platelets In Vitro and In Vivo (2004) (201)
- The role of platelet adhesion receptor GPIbα far exceeds that of its main ligand, von Willebrand factor, in arterial thrombosis (2006) (200)
- ADAMTS13: a new link between thrombosis and inflammation (2008) (199)
- Mice lacking the signaling molecule CalDAG-GEFI represent a model for leukocyte adhesion deficiency type III. (2007) (199)
- VWF-mediated leukocyte recruitment with chromatin decondensation by PAD4 increases myocardial ischemia/reperfusion injury in mice. (2014) (197)
- Localized reduction of atherosclerosis in von Willebrand factor-deficient mice. (2001) (193)
- Elevated levels of homocysteine compromise blood-brain barrier integrity in mice. (2005) (192)
- Regulated surface expression and shedding support a dual role for semaphorin 4D in platelet responses to vascular injury (2007) (191)
- Divergent fates of P- and E-selectins after their expression on the plasma membrane. (1993) (190)
- Platelet granule secretion continuously prevents intratumor hemorrhage. (2008) (189)
- Mx1 reveals innate pathways to antiviral resistance and lethal influenza disease (2016) (187)
- New links between inflammation and thrombosis. (2005) (187)
- Inflammation induces hemorrhage in thrombocytopenia. (2008) (179)
- NETosis: A New Factor in Tumor Progression and Cancer-Associated Thrombosis (2014) (176)
- PAD4-deficiency does not affect bacteremia in polymicrobial sepsis and ameliorates endotoxemic shock. (2015) (176)
- P-selectin mediates adhesion of platelets to neuroblastoma and small cell lung cancer. (1993) (175)
- Endocytosis of soluble immune complexes leads to their clearance by FcγRIIIB but induces neutrophil extracellular traps via FcγRIIA in vivo. (2012) (174)
- Initial glycosylation and acidic pH in the Golgi apparatus are required for multimerization of von Willebrand factor (1986) (169)
- Metalloproteinase inhibitors improve the recovery and hemostatic function of in vitro-aged or -injured mouse platelets. (2003) (167)
- Defect in regulated secretion of P-selectin affects leukocyte recruitment in von Willebrand factor-deficient mice (2001) (165)
- Desialylation accelerates platelet clearance after refrigeration and initiates GPIbα metalloproteinase-mediated cleavage in mice. (2012) (165)
- Extracellular Chromatin Is an Important Mediator of Ischemic Stroke in Mice (2012) (161)
- Fibrin induces release of von Willebrand factor from endothelial cells. (1987) (161)
- Priming of neutrophils toward NETosis promotes tumor growth (2016) (160)
- Citrullinated histone H3, a biomarker of neutrophil extracellular trap formation, predicts the risk of venous thromboembolism in cancer patients (2018) (160)
- Mechanisms and implications of platelet discoid shape. (2003) (159)
- P-selectin and E-selectin. Distinct but overlapping leukocyte ligand specificities. (1992) (159)
- Oxidized omega-3 fatty acids in fish oil inhibit leukocyte-endothelial interactions through activation of PPAR alpha. (2002) (159)
- Roles of PAD4 and NETosis in Experimental Atherosclerosis and Arterial Injury: Implications for Superficial Erosion (2018) (157)
- Reduced recruitment of inflammatory cells in a contact hypersensitivity response in P-selectin-deficient mice (1995) (155)
- von Willebrand Factor: An Emerging Target in Stroke Therapy (2012) (152)
- Inhibition of von Willebrand factor‐mediated platelet activation and thrombosis by the anti‐von Willebrand factor A1‐domain aptamer ARC1779 (2009) (150)
- ApoE Deficiency Compromises the Blood Brain Barrier Especially After Injury (2001) (149)
- Differential stimulation of monocytic cells results in distinct populations of microparticles (2008) (149)
- ApoE deficiency leads to a progressive age-dependent blood-brain barrier leakage. (2007) (148)
- Propolypeptide of von Willebrand factor circulates in blood and is identical to von Willebrand antigen II. (1986) (148)
- CD63 is a component of Weibel-Palade bodies of human endothelial cells. (1993) (147)
- Biosynthesis of von Willebrand protein by human endothelial cells. Identification of a large precursor polypeptide chain. (1983) (144)
- Cytokine-induced meningitis is dramatically attenuated in mice deficient in endothelial selectins. (1996) (142)
- Neutrophil elastase‐deficient mice form neutrophil extracellular traps in an experimental model of deep vein thrombosis (2016) (142)
- NETosis proceeds by cytoskeleton and endomembrane disassembly and PAD4-mediated chromatin decondensation and nuclear envelope rupture (2020) (141)
- Blood cell dynamics in P-selectin-deficient mice. (1995) (139)
- CalDAG-GEFI and protein kinase C represent alternative pathways leading to activation of integrin alphaIIbbeta3 in platelets. (2007) (138)
- VON WILLEBRAND FACTOR RELEASED FROM WEIBEL-PALADE BODIES BINDS MORE AVIDLY TO EXTRACELLULAR MATRIX THAN THAT SECRETED CONSTITUTIVELY (1987) (138)
- Role of syndecan-1 in leukocyte-endothelial interactions in the ocular vasculature. (2002) (134)
- A new role in hemostasis for the adhesion receptor P-selectin. (2004) (130)
- P-selectin, a granule membrane protein of platelets and endothelial cells, follows the regulated secretory pathway in AtT-20 cells (1992) (128)
- Cellular Mechanisms of NETosis. (2020) (127)
- Neutrophil cytoplasts induce TH17 differentiation and skew inflammation toward neutrophilia in severe asthma (2018) (125)
- Neutrophil extracellular traps (2013) (122)
- Platelet adhesion receptors and their ligands in mouse models of thrombosis. (2007) (121)
- Mac-1 signaling via Src-family and Syk kinases results in elastase-dependent thrombohemorrhagic vasculopathy. (2006) (120)
- Peptidylarginine deiminase 4 promotes age-related organ fibrosis (2017) (120)
- Insights into Selectin Function from Knockout Mice (1997) (118)
- NETosis promotes cancer-associated arterial microthrombosis presenting as ischemic stroke with troponin elevation. (2016) (118)
- Differing polarity of the constitutive and regulated secretory pathways for von Willebrand factor in endothelial cells (1989) (118)
- DIVERGENT PATES OF VON WILLEBRAND FACTOR AND ITS PROPOLYPEPTIDE (VON WILLEBRAND ANTIGEN II) AFTER SECRETION FROM ENDOTHELIAL CELLS (1987) (117)
- Tissue factor expressed by circulating cancer cell‐derived microparticles drastically increases the incidence of deep vein thrombosis in mice (2015) (117)
- Role of endothelial selectins in wound repair. (1997) (116)
- Plasma DNA is Elevated in Patients with Deep Vein Thrombosis. (2013) (113)
- A novel interaction between FlnA and Syk regulates platelet ITAM-mediated receptor signaling and function (2010) (113)
- Role of P-Selectin Cytoplasmic Domain in Granular Targeting In Vivo and in Early Inflammatory Responses (1998) (112)
- Peroxiredoxin1 Prevents Excessive Endothelial Activation and Early Atherosclerosis (2008) (109)
- In vitro multimerization of von Willebrand factor is triggered by low pH. Importance of the propolypeptide and free sulfhydryls. (1989) (107)
- von Willebrand factor proteolytic processing and multimerization precede the formation of Weibel-Palade bodies. (1994) (107)
- Flow cytometric assay for direct quantification of neutrophil extracellular traps in blood samples (2015) (106)
- A new class of obesity genes encodes leukocyte adhesion receptors. (1997) (106)
- Protective anti-inflammatory effect of ADAMTS13 on myocardial ischemia/reperfusion injury in mice. (2012) (101)
- Fibrinogen and von Willebrand factor‐independent platelet aggregation in vitro and in vivo (2006) (101)
- Oxidative stress activates ADAM17/TACE and induces its target receptor shedding in platelets in a p38-dependent fashion. (2009) (100)
- Topology and order of formation of interchain disulfide bonds in von Willebrand factor. (1987) (98)
- von Willebrand factor and factor VIII are independently required to form stable occlusive thrombi in injured veins. (2006) (97)
- GPVI down-regulation in murine platelets through metalloproteinase-dependent shedding (2004) (95)
- Acute passive anti-glomerular basement membrane nephritis in P-selectin-deficient mice. (1996) (94)
- Platelets: guardians of tumor vasculature. (2009) (93)
- p38 mitogen-activated protein kinase activation during platelet storage: consequences for platelet recovery and hemostatic function in vivo. (2010) (91)
- Rap1a activation by CalDAG‐GEFI and p38 MAPK is involved in E‐selectin‐dependent slow leukocyte rolling (2011) (88)
- Tumor necrosis factor-alpha-converting enzyme (ADAM17) mediates GPIbalpha shedding from platelets in vitro and in vivo. (2004) (86)
- A Direct Role for C1 Inhibitor in Regulation of Leukocyte Adhesion 1 (2005) (85)
- Von Willebrand protein binds to extracellular matrices independently of collagen. (1984) (85)
- Glycoprotein Ibα and von Willebrand factor in primary platelet adhesion and thrombus formation: Lessons from mutant mice (2008) (84)
- Extracellular DNA NET-Works With Dire Consequences for Health. (2019) (84)
- Thrombocytopenia and Platelet Abnormalities in High-Density Lipoprotein Receptor–Deficient Mice (2008) (83)
- Similarities and differences between the fibronectins of normal and transformed hamster cells. (1981) (81)
- Antithrombotic activity of TNF-α (2003) (81)
- Plasma selenium-dependent glutathione peroxidase. Cell of origin and secretion. (1989) (80)
- Innate immune cells induce hemorrhage in tumors during thrombocytopenia. (2009) (80)
- Control of thrombus embolization and fibronectin internalization by integrin αIIbβ3 engagement of the fibrinogen γ chain (2003) (80)
- PSGL-1 regulates platelet P-selectin-mediated endothelial activation and shedding of P-selectin from activated platelets (2007) (78)
- The distal carboxyl-terminal domains of ADAMTS13 are required for regulation of in vivo thrombus formation. (2009) (78)
- Domain structure of fibronectin and its relation to function. Disulfides and sulfhydryl groups. (1979) (77)
- von Willebrand factor and the endothelium. (1991) (77)
- Cell surface fibronectin and oncogenic transformation. (1979) (76)
- Characterization of a novel adhesion function blocking monoclonal antibody to rat/mouse P-selectin generated in the P-selectin-deficient mouse. (1997) (75)
- The Role of Platelet Adhesion Receptor GPIb α Far Exceeds That of Its Main Ligand von Willebrand Factor in Arterial Thrombosis. (2006) (75)
- Peptidylarginine deiminase 4: a nuclear button triggering neutrophil extracellular traps in inflammatory diseases and aging (2018) (73)
- Elevated levels of soluble P-selectin in mice alter blood-brain barrier function, exacerbate stroke, and promote atherosclerosis. (2009) (73)
- The combined roles of ADAMTS13 and VWF in murine models of TTP, endotoxemia, and thrombosis. (2008) (72)
- Topological arrangement of the major structural features of fibronectin. (1980) (72)
- Overlapping functions of E- and P-selectin in neutrophil recruitment during acute inflammation. (1998) (71)
- Increased thrombogenesis and embolus formation in mice lacking glycoprotein V. (2001) (70)
- Formation of platelet strings and microthrombi in the presence of ADAMTS‐13 inhibitor does not require P‐selectin or β3 integrin (2007) (69)
- von Willebrand factor proteolytic processing and multimerization precede the formation of Weibel-Palade bodies (1994) (66)
- Increased efficacy of breast cancer chemotherapy in thrombocytopenic mice. (2011) (65)
- Decreased Plasma Fibronectin Leads to Delayed Thrombus Growth in Injured Arterioles (2006) (64)
- von Willebrand Factor Biosynthesis and Processing a (1991) (64)
- Inhibition of VEGF or TGF-β Signaling Activates Endothelium and Increases Leukocyte Rolling (2009) (62)
- Endothelial Von Willebrand Factor Promotes Blood–Brain Barrier Flexibility and Provides Protection From Hypoxia and Seizures in Mice (2013) (62)
- Resolvin D4 attenuates the severity of pathological thrombosis in mice. (2019) (61)
- Aspirin Induces Platelet Receptor Shedding via ADAM17 (TACE)* (2005) (57)
- Relationships between microfilaments, cell-substratum adhesion, and fibronectin. (1982) (57)
- Leukocyte-endothelium adhesion molecules in atherosclerosis. (1998) (56)
- Genetic manipulation of vascular adhesion molecules in mice. (1996) (56)
- Plasma Peptidylarginine Deiminase IV Promotes VWF-Platelet String Formation and Accelerates Thrombosis after Vessel Injury. (2019) (55)
- Rolling in P-selectin-deficient mice is reduced but not eliminated in the dorsal skin. (1995) (54)
- ARC15105 Is a Potent Antagonist of Von Willebrand Factor Mediated Platelet Activation and Adhesion (2012) (53)
- Control of thrombus embolization and fibronectin internalization by integrin alpha IIb beta 3 engagement of the fibrinogen gamma chain. (2003) (53)
- Experimental murine acid aspiration injury is mediated by neutrophils and the alternative complement pathway. (1997) (53)
- Interleukin 11 significantly increases plasma von Willebrand factor and factor VIII in wild type and von Willebrand disease mouse models. (2001) (53)
- von-Willebrand factor influences blood brain barrier permeability and brain inflammation in experimental allergic encephalomyelitis. (2008) (52)
- Extrahepatic High-Density Lipoprotein Receptor SR-BI and ApoA-I Protect Against Deep Vein Thrombosis in Mice (2012) (52)
- Prothrombotic Effects of Fibronectin Isoforms Containing the EDA Domain (2007) (52)
- Mast Cells Granular Contents Are Crucial for Deep Vein Thrombosis in Mice (2017) (52)
- Hypoxia, such as encountered at high altitude, promotes deep vein thrombosis in mice (2013) (51)
- In vitro function and phagocytosis of galactosylated platelet concentrates after long‐term refrigeration (2007) (51)
- Requirement for Both D Domains of the Propolypeptide in von Willebrand Factor Muitimerization and Storage (1993) (49)
- Mediation of fibrin-induced release of von Willebrand factor from cultured endothelial cells by the fibrin beta chain. (1989) (49)
- von Willebrand factor biosynthesis and partitioning between constitutive and regulated pathways of secretion after thrombin stimulation. (1989) (48)
- Irradiation induces release of von Willebrand protein from endothelial cells in culture (1984) (48)
- Serotonin stimulates platelet receptor shedding by tumor necrosis factor‐alpha‐converting enzyme (ADAM17) (2009) (47)
- Neutrophil phenotypes and functions in cancer: A consensus statement (2022) (47)
- Insights from von Willebrand disease animal models (1999) (47)
- Generation and characterization of a novel adhesion function blocking monoclonal antibody recognizing both rat and mouse E-selectin. (1997) (47)
- Antithrombotic activity of TNF-alpha. (2003) (46)
- Unraveling Vascular Inflammation: From Immunology to Imaging. (2017) (46)
- Infection-mediated early-onset periodontal disease in P/E-selectin-deficient mice. (2001) (46)
- NLRP3 Inflammasome Assembly in Neutrophils Is Supported by PAD4 and Promotes NETosis Under Sterile Conditions (2021) (46)
- von Willebrand factor storage requires intact prosequence cleavage site. (1993) (44)
- Human endothelial cells synthesize, process, and secrete fibronectin molecules bearing an alternatively spliced type III homology (ED1). (1990) (43)
- Irradiation induces release of von Willebrand protein from endothelial cells in culture. (1984) (42)
- Elevated soluble ICAM‐1 levels induce immune deficiency and increase adiposity in mice (2005) (41)
- Mice lacking insulin or insulin-like growth factor 1 receptors in vascular endothelial cells maintain normal blood-brain barrier. (2004) (40)
- A 130-kDa protein on endothelial cells binds to amino acids 15-42 of the B beta chain of fibrinogen. (1992) (40)
- New Discoveries with Mice Mutant in Endothelial and Platelet Selectins (1999) (38)
- INTACT MICROTUBULES ARE NECESSARY FOR COMPLETE PROCESSING, STORAGE AND REGULATED SECRETION OF VON WILLEBRAND FACTOR BY ENDOTHELIAL CELLS (1987) (37)
- Molecular and cellular biology of von Willebrand factor. (1989) (36)
- The development of inflammatory joint disease is attenuated in mice expressing the anticoagulant prothrombin mutant W215A/E217A. (2011) (34)
- Biosynthesis of von Willebrand Protein by Human Endothelial Cells" Processing and Their Intracellular Localization Steps (1984) (34)
- P-Selectin and Platelet Clearance (1998) (34)
- Platelet glycoprotein Ibα is an important mediator of ischemic stroke in mice (2011) (33)
- The Lack of ADAM17 Activity during Embryonic Development Causes Hemorrhage and Impairs Vessel Formation (2010) (31)
- Inflammasome activation in neutrophils of patients with severe COVID-19 (2022) (31)
- Neutrophils release extracellular DNA traps during storage of red blood cell units (2013) (31)
- Donor MHC and adhesion molecules in transplant arteriosclerosis. (1999) (30)
- ADAMTS13 exerts a thrombolytic effect in microcirculation (2012) (30)
- PAD4 Deficiency Decreases Inflammation and Susceptibility to Pregnancy Loss in a Mouse Model (2016) (29)
- Isoflurane inhibits neutrophil recruitment in the cutaneous Arthus reaction model (2013) (29)
- A key role for Rac and Pak signaling in neutrophil extracellular traps (NETs) formation defines a new potential therapeutic target (2018) (28)
- Angiogenesis in P‐ and E‐Selectin‐Deficient Mice (1998) (28)
- Integrin‐independent role of CalDAG‐GEFI in neutrophil chemotaxis (2010) (28)
- Inhibition of disulfide bonding of von Willebrand protein by monensin results in small, functionally defective multimers (1985) (27)
- The effect of C1 inhibitor on intestinal ischemia and reperfusion injury. (2008) (25)
- The transmembrane domain enhances granular targeting of P-selectin. (1998) (24)
- Targeting platelet function to improve drug delivery (2012) (24)
- Genetic manipulation of vascular adhesion molecules in mice. (1997) (22)
- ADAMTS 13 : a new link between thrombosis and infl ammation (2008) (22)
- P- and E-selectin-deficient mice are susceptible to cerebral ischemia–reperfusion injury (1999) (20)
- Recombinant Human ADAMTS13 Treatment Improves Myocardial Remodeling and Functionality After Pressure Overload Injury in Mice (2018) (18)
- Lack of Tryptophan Hydroxylase-1 in Mice Results in Gait Abnormalities (2013) (18)
- P- and E-selectins are required for the leukocyte recruitment, but not the tissue swelling, associated with IgE- and mast cell-dependent inflammation in mouse skin. (1998) (17)
- Fibronectin-coated beads are endocytosed by cells and align with microfilament bundles. (1982) (16)
- Platelet adhesion receptors do not modulate infarct volume after a photochemically induced stroke in mice (2007) (15)
- P-selectin knockout: a mouse model for various human diseases. (2007) (13)
- Dietary omega-3 alpha-linolenic acid does not prevent venous thrombosis in mice (2014) (13)
- Thromboinflammation: From Atherosclerosis to COVID-19. (2022) (12)
- ADAMTS13 Endopeptidase Protects against Vascular Endothelial Growth Factor Inhibitor-Induced Thrombotic Microangiopathy. (2016) (11)
- Limiting prothrombin activation to meizothrombin is compatible with survival but significantly alters hemostasis in mice. (2016) (11)
- Sirt3 deficiency does not affect venous thrombosis or NETosis despite mild elevation of intracellular ROS in platelets and neutrophils in mice (2017) (11)
- ADAMTS13 Deficiency Worsens Colitis and Exogenous ADAMTS13 Administration Decreases Colitis Severity in Mice (2017) (10)
- ICAM-1 and β2 Integrin Deficiency Impairs Fat Oxidation and Insulin Metabolism during Fasting (2004) (10)
- Neutrophil stimulation with citrullinated histone H4 slows down calcium influx and reduces NET formation compared with native histone H4 (2021) (9)
- CD 63 Is a Component of Weibel-Palade Bodies of Human Endothelial Cells (2003) (9)
- P-selectin chases a butterfly. (1995) (8)
- OC-16 - Neutrophil extracellular traps and tissue factor-bearing microvesicles: a liaison dangereuse causing overt DIC in cancer patients? (2016) (8)
- Temperature-sensitive steps in the secretory pathway for von Willebrand factor in endothelial cells. (1989) (8)
- Solid peripheral tumor leads to systemic inflammation, astrocyte activation and signs of behavioral despair in mice (2018) (8)
- P-selectin and E-selectin (2001) (8)
- Recombinant human ADAMTS13 treatment and anti‐NET strategies enhance skin allograft survival in mice (2019) (7)
- E and P selectins are not required for resistance to severe murine lyme arthritis. (1998) (7)
- Tumor Necrosis Factor-– Converting Enzyme ( ADAM 17 ) Mediates GPIb Shedding From Platelets In Vitro and In Vivo (2004) (7)
- Double knockout highlights value of endothelial selectins. (1996) (7)
- NETosis proceeds by cytoskeleton and endomembrane disassembly and PAD4-mediated chromatin de-condensation and nuclear envelope rupture (2019) (7)
- CHAPTER 39 – Inflammation (2007) (6)
- Neutrophil Extracellular Traps Induce Platelet Adhesion and Thrombus Formation. (2009) (6)
- The role of SERPIN citrullination in thrombosis. (2021) (6)
- Carboxypeptidase E does not mediate von Willebrand factor targeting to storage granules. (1999) (5)
- CalDAG-GEFI And Protein Kinase C (PKC) Represent Alternative Pathways Leading To Activation Of Integrin α IIb β 3 In Platelets (2008) (5)
- PADGEM, a Leukocyte Receptor on Activated Platelets (1991) (5)
- Integrin-Independent Role of CalDAG-GEFI in Neutrophil Chemotaxis. (2008) (5)
- Correction: Lack of Tryptophan Hydroxylase-1 in Mice Results in Gait Abnormalities (2013) (5)
- Citrullinated Fibrinogen Renders Clots Mechanically Less Stable, but Lysis-Resistant (2021) (4)
- VWF-Cleaving Protease ADAMTS13 Reduces Brain Injury Following Ischemic Stroke in Mice: Essential Role for VWF in Stroke (2008) (4)
- The role of platelets in thrombus fibrosis and vessel wall remodeling after venous thrombosis (2020) (4)
- Abstract 448: Platelets Contribute to Arterial and Venous Thrombosis in vivo (2007) (4)
- Supporting Online Material for Dynamic Visualization of Thrombopoiesis Within Bone Marrow (2007) (4)
- PADGEM, a leukocyte receptor on activated platelets. Biology and application to in vivo medical diagnostics. (1991) (4)
- PSelectin, A Granule Membrane Protein of Platelets and Endothelial Cells, Follows the Regulated Secretory Pathway in AtT20 Cells (2002) (3)
- Wagner and Burger Platelets in Inflammation and Thrombosis 2133 (2003) (3)
- Heme-Induced Neutrophil Extracellular Traps (NETs) Formation Contributes To Sickle Cell Disease Pathogenesis (2013) (3)
- The effect of C 1 inhibitor on intestinal ischemia and reperfusion injury (2008) (3)
- Metalloproteinase Inhibitors Increase the Survival of Long-Term Refrigerated Platelets in Mice. (2007) (3)
- Formation of Platelet Strings and Microthrombi in the Presence of ADAMTS13 Inhibitor Does Not Require P-Selectin or β3 Integrin. (2006) (3)
- Erratum: CalDAG-GEFI integrates signaling for platelet aggregation and thrombus formation (2004) (3)
- The Metalloprotease ADAMTS13 Is a Natural Anti-Thrombotic. (2005) (2)
- Reduced Plasma Fibronectin Leads to Delayed Thrombus Growth in the Injured Arterioles in Vivo. (2004) (2)
- Recombinant ADAMTS13 Improves Neurological Outcome in Experimental Stroke in Mice. (2009) (2)
- Systemic antithrombotic eff ects of ADAMTS13 (2006) (2)
- VWF-Mediated Platelet Adhesion is Required for Deep Vein Thrombosis in a Flow Restriction Model. (2009) (2)
- Cancer-Associated Thrombosis: Cancer Cell-Derived Microparticles As a Trigger of Venous Thrombosis in a Mouse Model of Flow Restriction (2011) (2)
- Differential Changes in Platelet VWF Receptor Following Refrigeration for Short or Long Periods. (2005) (2)
- E and P Selectins Are Not Required for Resistance to Severe Murine Lyme Arthritis (1998) (2)
- Thrombosis in Myeloproliferative Neoplasms Is Linked to Increased Neutrophil Extracellular Trap (NET) Formation (2016) (2)
- The Prominent Role of Hematopoietic Peptidyl Arginine Deiminase 4 in Arthritis: Collagen‐ and Granulocyte Colony‐Stimulating Factor–Induced Arthritis Model in C57BL/6 Mice (2022) (2)
- Fuchs et al Neutrophil Extracellular Trap Impact on Deep Vein Thrombosis 3 (2)
- The Generation of An Aptamer Inhibitor of Murine Von Willebrand Factor (VWF) Mediated Platelet Aggregation (2010) (2)
- Downregulation of P-Selectin from Activated Platelets Involves Both Receptor Internalization and Shedding upon Binding to PSGL-1. (2005) (1)
- The Role of Rac and Pak in Neutrophil Histone Hypercitrullination and Neutrophil Extracellular Traps Formation (2014) (1)
- in humans and mice Extracellular DNA traps are associated with the pathogenesis of TRALI (2012) (1)
- ROLE OF PLASMA FIBRONECTIN IN FIBRINOGEN/VWF-INDEPENDENT THROMBUS FORMATION (2007) (1)
- Deficiency of the VWF-Cleaving Protease ADAMTS13 Results in Increased Leukocyte Rolling and Adhesion in Mice. (2007) (1)
- PHAGOCYTES , GRANULOCYTES , AND MYELOPOIESIS PAD 4-de fi ciency does not affect bacteremia in polymicrobial sepsis and ameliorates endotoxemic shock (2015) (1)
- CalDAG-GEFI Is a Key Signal Integrator in Platelet Activation and Thrombus Formation. (2004) (1)
- Elevated Threshold Shear Rate for the Dependence of Glycoprotein Ibα-Mediated Platelet Thrombus Formation onto Immobilized von Willebrand Factor in Mouse Blood. (2004) (1)
- Mice with Genetic Modifications in Prothrombin Limiting Activation Cleavage Events to Meizothrombin Survive to Adulthood, but Exhibit Alterations in Hemostasis and Thrombus Formation (2012) (1)
- Filamin A Deficiency in Platelets Reveals Functional Impairment in ITAM-Based Signaling. (2009) (1)
- NLRP3 inflammasome activation in neutrophils directs early inflammatory response in murine peritonitis (2022) (1)
- Neutrophil Extracellular Traps and von Willebrand Factor in Thrombosis (2014) (1)
- Heparin Prevents Histone-Induced Thrombocytopenia and Mortality. (2010) (1)
- Anti‐inflammatory protective effect of ADAMTS‐13 in murine arthritis models (2022) (1)
- Abstract 17883: Neutrophil Extracellular Traps as an Interface Between Inflammation and Thrombosis in DVT (2011) (0)
- Abstract 224: Cleavage of DNA Generated During Myocardial Ischemia/Reperfusion Protects the Heart from Injury (2012) (0)
- Abstract 18175: Interaction of Platelets, Leukocytes and Released Neutrophil Extracellular Traps (NETs) Promote Deep Vein Thrombosis in vivo (2011) (0)
- CALDAG-GEFI-DEFICIENCY CAUSES IMPAIRED BETA1, BETA2, AND BETA3 INTEGRIN ACTIVATION IN NEUTROPHILS AND PLATELETS: A MODEL FOR LEUKOCYTE ADHESION DEFICIENCY-III (LAD-III) (2007) (0)
- Abstract 54: Peptidylarginine Deiminase 4-dependent Generation of Neutrophil Extracellular Traps is Crucial for Deep Vein Thrombosis in Mice (2013) (0)
- 335. Correction of a Murine Model of Von Willebrand Disease by Gene Transfer (2005) (0)
- Absence Of Adamts13 On A Vwf Deficient Background Is No Longer Prothrombotic In A Murine Model Of Arterial Thrombosis (2007) (0)
- Dietary Alpha-Linolenic Acid Does Not Protect From Venous Thrombosis In The Vena Cava Stenosis Model (2013) (0)
- 160. Overcoming the size limitations of gene transfer vectors: using segmental trans-splicing to deliver the coding sequence of Von Willebrand factor (2004) (0)
- Mice Lacking the Signaling Molecule, CalDAG-GEFI, Represent a Mouse Model for Leukocyte Adhesion Deficiency Type III. (2006) (0)
- The effect of C1 inhibitor on intestinal ischaemia and reperfusion injury (2008) (0)
- Neutrophil extracellular traps The Harvard community has made this article openly available. Please share how this access benefits you. Your story matters (2013) (0)
- Unraveling Vascular Inflammation (0)
- Alleviation of arthritis through prevention of neutrophil extracellular traps by an orally available inhibitor of protein arginine deiminase 4 (2023) (0)
- integrin {alpha}IIb{beta}3 engagement of the fibrinogen {gamma} chain Control of thrombus embolization and fibronectin internalization by (2010) (0)
- METHOD FOR THE TREATMENT OF DISORDERS hemostatic by soluble P-selectin (2001) (0)
- Interleukin 11 significantly increases plasma von Willebrand factor and factor VIII in wild type and von Willebrand disease mouse models (2000) (0)
- permeability of the blood-brain barrier in adult rats Effects of acute hypoxia and hyperthermia on the (2015) (0)
- Oxidized omega-3 fatty acids in fish oil inhibit leukocyte-endothelial interactions through activation of PPARα Short title: Oxidized n-3 fatty acids inhibit inflammation via PPARα (2002) (0)
- stable occlusive thrombi in injured veins von Willebrand factor and factor VIII are independently required to form (2013) (0)
- Neutrophil extracellular traps The Harvard community has made this article openly available. Please share how this access benefits you. Your story matters (2013) (0)
- Abstract 1941: The Anti Von Willebrand Factor Aptamer ARC1779 Effectively Inhibits Platelet Activation and Adhesion (2008) (0)
- Antithrombotic activity of TNF-a Beatrice Cambien (2018) (0)
- PRESTIGE – Final Workshop (0)
- Inflammation induces hemorrhage in thrombocytopenia. Commentary (2008) (0)
- Compositions with thrombolytic activity comprising ADAMTS13 (2006) (0)
- The combined roles ofADAMTS13 and VWF in murine models of TTP, endotoxemia, and thrombosis. Commentary (2008) (0)
- expressing the anticoagulant prothrombin mutant W215A/E217A The development of inflammatory joint disease is attenuated in mice (2012) (0)
- Leukocytes fighting against obesity (1998) (0)
- Thrombocytopenia Induced-Tumor Vascular Leakiness Increases Drug Efficacy (2010) (0)
- Preface (2009) (0)
- GPIbα Is Essential for Platelet Adhesion during Thrombus Formation: Studies with Mutant Mice Deficient in the Extracellular Domain of GPIbα. (2004) (0)
- How Do Platelets Stabilize Tumor Vessels ? (2009) (0)
- Loss of Barrier Function in Senescent Vessels Due to Constitutive Inflammation (2004) (0)
- The effect of Cl inhibitor on intestinal ischemia and reperfusion injury (2008) (0)
- Abstract 3733: Platelet Serotonin Receptor Stimulation Induces Shedding of the Adhesion Molecule GPIb{alpha} (2008) (0)
- A Threshold Level of Von Willebrand Factor Is Required for Disease Pathogenesis in a Mouse Model of TTP. (2006) (0)
- p38 MAPK Inhibition Prevents TACE-Mediated Receptor Shedding and Improves the Hemostatic Function of Stored Platelets. (2008) (0)
- Analysis of Aptamer Concentrations in Cynomolgus Macaque Plasma and in the Serum Stability Study (2012) (0)
- Mechanisms of Statin-Induced Myopathy Apolipoprotein AV: Low Concentration, High Impact Chemokine Receptors in Atherosclerosis and HIV Infection (2005) (0)
- Fibrinogen and von Willebrand Factor-Independent Platelet Aggregation: The Essential Roles of β3 Integrin, Thrombin, and Divalent Ca2+ Cations. (2005) (0)
- Inhibition of Sialic Acid Loss Greatly Improves Survival of Refrigerated Platelets (2011) (0)
- Reply to Liu: The disassembly of the actin cytoskeleton is an early event during NETosis (2020) (0)
- Key Words : deep vein thrombosis n deoxyribonuclease n inflammation n mouse model n neutrophil extracellular traps Neutrophil Extracellular Trap Impact on Deep Vein Thrombosis (0)
- Fibronectin Is Not the Only Important Molecule Required for Fibrinogen/VWF-Independent Platelet Aggregation: Study of Thrombosis in a New Strain of Triple Deficient Mice. (2006) (0)
- The Role of VWF In BBB Permeability Associated with Hypoxia/Reoxygenation (2010) (0)
- The F-BAR Protein PACSIN2 Regulates Platelet Intracellular Membrane Architecture and in Vivo Hemostatic Functions (2014) (0)
- Shear madness in TNF-α signaling (2003) (0)
- A025 P38 MAPK inhibition prevents TACE-mediated receptor shedding and improves the hemostatic function of stored platelets (2009) (0)
- Platelets Protect Tumors from Hemorrhage Induced by Stroma-Infiltrating Leukocytes (2008) (0)
- Roles of plasma fibronectin in thrombosis and hemostasis: A lesson from fibrinogen/VWF/and plasma finronectin triple knockout mice (2008) (0)
- Addressing the Issue of the Pathogenesis of Deep Vein Thrombosis In Cancer (2010) (0)
- A026 Serotonin stimulates platelet receptor shedding by tumor necrosis factor-alpha-converting enzyme (ADAM17) (2009) (0)
- Circulating Nucleosomes Reflect Disease Activity in Patients with Thrombotic Microangiopathies. (2010) (0)
- interactions through activation of PPARalpha Oxidized omega-3 fatty acids in fish oil inhibit leukocyte-endothelial (2010) (0)
- CalDAG-GEF-I is required for E-selectin-dependent slow leukocyte rolling (94.2) (2009) (0)
- PAD4 Promotes NLRP3 Inflammasome Assembly Leading to NETosis (2019) (0)
- CHARACTERIZATION OF THE ROLE OF PLATELET ADHESION MOLECULES IN A MURINE MODEL OF PHOTOSENSITIZER-INDUCED STROKE (2007) (0)
- acute inflammation in mice Platelet serotonin promotes the recruitment of neutrophils to sites of (2013) (0)
- avidly to extracellular matrix than that secreted constitutively von Willebrand factor released from Weibel-Palade bodies binds more (2011) (0)
- CalDAG-GEFI and protein kinase C represent alternative pathways leading to activation of integrin (cid:1) IIb (cid:2) 3 in platelets (2008) (0)
- Title: P-selectin promotes neutrophil extracellular trap formation in mice Short title: P-selectin in NET formation (2016) (0)
- RIIIB but induces neutrophil extracellular traps via Fc γ Endocytosis of soluble immune complexes leads to their clearance (2012) (0)
- deficient mice − Localized reduction of atherosclerosis in von Willebrand factor (2001) (0)
- Divergent Fates ofP-andE-Selectins After Their Expression onthePlasma Membrane (1993) (0)
- 4 increases myocardial ischemia / reperfusion injury in mice VWF-mediated leukocyte recruitment with chromatin decondensation (2013) (0)
- Mice Engineered To Express a Form of Thrombin Favoring Protein C Are Resistant to S. aureus-Induced Sepsis. (2007) (0)
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What Schools Are Affiliated With Denisa D Wagner?
Denisa D Wagner is affiliated with the following schools:
