Dennis C. Liotta | Academic Influence

Dennis C. Liotta's AcademicInfluence.com Rankings

Dennis C. Liotta

Chemistry

#724

World Rank

#1219

Historical Rank

#314

USA Rank

chemistry Degrees

Download Badge

Chemistry

Dennis C. Liotta's Degrees

PhD Chemistry University of Maryland, College Park
Bachelors Chemistry University of Notre Dame

Why Is Dennis C. Liotta Influential?

(Suggest an Edit or Addition)

According to Wikipedia, Dennis Liotta is a chemistry professor at Emory University in Atlanta, Georgia, United States. He is noted for his work on the development of antiviral drugs. Career Liotta's fields of research are organic synthesis and medicinal chemistry. Along with Dr. Raymond F. Schinazi and Dr. Woo-Baeg Choi of Emory, he invented Emtricitabine, which is a breakthrough HIV drug. Emory University sold its royalties on the drug to Royalty Pharma and Gilead Sciences in July 2005 for $525 million. It is currently marketed under the name Emtriva. Emtriva is a component of a number of combination therapies used to treat HIV, including Truvada, Atripla, Complera, Stribild, Genvoya, Odefesey, Biktarvy, Descovy, and Symtuza. Truvada is the only combination therapy approved for Pre-Exposure Prophylaxis . Liotta, Choi and Schinazi also co-invented Epivir , which is a component of multiple combination therapies such as Combivir, Trizivir, Epzicom, Triumeq, Dutrebis and Delstrigo. It is estimated that >90% of HIV infected patients in the US take or have taken drug combinations that include either Emtriva or Epivir. In addition, he was one of the inventors of Epivir-HBV, the first drug approved to treat hepatitis B infections.

(See a Problem?)

Dennis C. Liotta's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Inhibition of the replication of hepatitis B virus in vitro by 2',3'-dideoxy-3'-thiacytidine and related analogues. (1991) (496)
Characterization of human immunodeficiency viruses resistant to oxathiolane-cytosine nucleosides (1993) (379)
Thematic Review Series: Sphingolipids. Biodiversity of sphingoid bases (“sphingosines”) and related amino alcohols* (2008) (350)
Synthesis and biological evaluation of novel curcumin analogs as anti-cancer and anti-angiogenesis agents. (2004) (345)
Polyoxometalate HIV-1 protease inhibitors. A new mode of protease inhibition. (2001) (316)
Quantitation of free sphingosine in liver by high-performance liquid chromatography. (1988) (296)
Selectivity of ceramide-mediated biology. Lack of activity of erythro-dihydroceramide. (1993) (289)
Deoxycytidine deaminase-resistant stereoisomer is the active form of (+/-)-2',3'-dideoxy-3'-thiacytidine in the inhibition of hepatitis B virus replication. (1992) (220)
The anti-hepatitis B virus activities, cytotoxicities, and anabolic profiles of the (-) and (+) enantiomers of cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine (1992) (213)
EF24, a novel synthetic curcumin analog, induces apoptosis in cancer cells via a redox-dependent mechanism (2005) (203)
Fumonisins and fumonisin analogs as inhibitors of ceramide synthase and inducers of apoptosis. (2002) (176)
Acylation of Naturally Occurring and Synthetic 1-Deoxysphinganines by Ceramide Synthase (1998) (152)
Inhibition of the NF-κB signaling pathway by the curcumin analog, 3,5-Bis(2-pyridinylmethylidene)-4-piperidone (EF31): anti-inflammatory and anti-cancer properties. (2012) (151)
Bimodal Regulation of Ceramidase by Interleukin-1β (1997) (151)
Chemical synthesis and biological evaluation of cis- and trans-12,13-cyclopropyl and 12,13-cyclobutyl epothilones and related pyridine side chain analogues. (2001) (149)
A subunit-selective potentiator of NR2C- and NR2D-containing NMDA receptors. (2010) (149)
Inhibition of IκB Kinase-Nuclear Factor-κB Signaling Pathway by 3,5-Bis(2-flurobenzylidene)piperidin-4-one (EF24), a Novel Monoketone Analog of Curcumin (2008) (145)
Disruption of sphingolipid metabolism and stimulation of DNA synthesis by fumonisin B1. A molecular mechanism for carcinogenesis associated with Fusarium moniliforme. (1994) (143)
Highly active anticancer curcumin analogues. (2007) (141)
Fumonisins: fungal toxins that shed light on sphingolipid function. (1996) (138)
The development of a selective cyclin-dependent kinase inhibitor that shows antitumor activity. (2009) (121)
Development of a Unique Small Molecule Modulator of CXCR4 (2012) (118)
In situ complexation directs the stereochemistry of N-glycosylation in the synthesis of oxathiolanyl and dioxolanyl nucleoside analogues (1991) (114)
Total synthesis of SR 121463 A, a highly potent and selective vasopressin v(2) receptor antagonist. (2001) (106)
New organoselenium methodology (1984) (106)
EF24, a novel curcumin analog, disrupts the microtubule cytoskeleton and inhibits HIF-1 (2008) (106)
Ceramide stimulates epidermal growth factor receptor phosphorylation in A431 human epidermoid carcinoma cells. Evidence that ceramide may mediate sphingosine action. (1991) (104)
Discovery of small molecule CXCR4 antagonists. (2007) (102)
A stereoselective synthesis of sphingosine, a protein kinase c inhibitor (1988) (96)
Mechanism for Noncompetitive Inhibition by Novel GluN2C/D N-Methyl-d-aspartate Receptor Subunit-Selective Modulators (2011) (92)
Affinity of the antiviral enantiomers of oxathiolane cytosine nucleosides for human 2'-deoxycytidine kinase. (1993) (92)
Sphingoid bases and de novo ceramide synthesis: enzymes involved, pharmacology and mechanisms of action. (2003) (92)
Fumonisin toxicity and sphingolipid biosynthesis. (1996) (90)
Quinazolin-4-one derivatives: A novel class of noncompetitive NR2C/D subunit-selective N-methyl-D-aspartate receptor antagonists. (2010) (90)
Suppression of aberrant colonic crypt foci by synthetic sphingomyelins with saturated or unsaturated sphingoid base backbones. (1997) (89)
Pure nucleoside enantiomers of beta-2',3'-dideoxycytidine analogs are selective inhibitors of hepatitis B virus in vitro (1994) (88)
Free sphingosine formation from endogenous substrates by a liver plasma membrane system with a divalent cation dependence and a neutral pH optimum. (1989) (87)
Characteristics of the growth inhibition and cytotoxicity of long-chain (sphingoid) bases for Chinese hamster ovary cells: evidence for an involvement of protein kinase C. (1990) (85)
The Ecstasy and Agony of Assay Interference Compounds. (2017) (83)
Modulation of the free sphingosine levels in human neutrophils by phorbol esters and other factors. (1988) (82)
A unified and quantitative receptor model for the microtubule binding of paclitaxel and epothilone. (1999) (80)
Synthesis of EF24-tripeptide chloromethyl ketone: a novel curcumin-related anticancer drug delivery system. (2006) (79)
A target site for template-based design of measles virus entry inhibitors. (2004) (76)
Phenyl selenide anion, a superior reagent for the SN2 cleavage of esters and lactones (1981) (73)
Stereoselectivity of electrophile-promoted cyclizations of .gamma.-hydroxyalkenes. An investigation of carbohydrate-derived and model substrates (1987) (72)
GluN2D-Containing N-methyl-d-Aspartate Receptors Mediate Synaptic Transmission in Hippocampal Interneurons and Regulate Interneuron Activity (2016) (72)
Origins of the enantioselectivity observed in oxazaborolidine-catalyzed reductions of ketones (1993) (71)
Enzyme-mediated enantioselective preparation of pure enantiomers of the antiviral agent 2',3'-dideoxy-5-fluoro-3'-thiacytidine (FTC) and related compounds (1992) (69)
The oxetane ring in taxol. (2000) (67)
Novel NMDA receptor modulators: an update (2012) (66)
Structural Determinants and Mechanism of Action of a GluN2C-selective NMDA Receptor Positive Allosteric Modulator (2014) (66)
Monocarbonyl analogs of curcumin inhibit growth of antibiotic sensitive and resistant strains of Mycobacterium tuberculosis. (2015) (65)
A novel pyrazolo[1,5-a]pyrimidine is a potent inhibitor of cyclin-dependent protein kinases 1, 2, and 9, which demonstrates antitumor effects in human tumor xenografts following oral administration. (2010) (64)
A simple method for the efficient synthesis of unsaturated .beta.-dicarbonyl compounds (1981) (62)
A COMPLETELY DIASTEREOSELECTIVE ELECTROPHILIC FLUORINATION OF A CHIRAL, NONCARBOHYDRATE SUGAR RING PRECURSOR : APPLICATION TO THE SYNTHESIS OF SEVERAL NOVEL 2'-FLUORONUCLEOSIDES (1998) (59)
Dipyrimidine amines: a novel class of chemokine receptor type 4 antagonists with high specificity. (2010) (58)
Nonpeptide inhibitors of measles virus entry. (2006) (58)
Design of a Small-Molecule Entry Inhibitor with Activity against Primary Measles Virus Strains (2005) (56)
DPC 817: a Cytidine Nucleoside Analog with Activity against Zidovudine- and Lamivudine-Resistant Viral Variants (2002) (54)
Effects of substitution on intramolecular alkoxypalladation carbonylation reactions (1989) (54)
Ceramide-beta-D-glucuronide: synthesis, digestion, and suppression of early markers of colon carcinogenesis. (1999) (54)
The Ecstasy and Agony of Assay Interference Compounds (2017) (53)
Activation of the p38 pathway by a novel monoketone curcumin analog, EF24, suggests a potential combination strategy. (2010) (53)
An Orally Available, Small-Molecule Polymerase Inhibitor Shows Efficacy Against a Lethal Morbillivirus Infection in a Large Animal Model (2014) (52)
Context-Dependent GluN2B-Selective Inhibitors of NMDA Receptor Function Are Neuroprotective with Minimal Side Effects (2015) (51)
Curcumin analog cytotoxicity against breast cancer cells: exploitation of a redox-dependent mechanism. (2009) (51)
A general method for controlling glycosylation stereochemistry in the synthesis of 2'-deoxyribose nucleosides (1990) (50)
A simple, efficient synthesis of 3-substituted furans (1983) (50)
The generation of uncomplexed phenyl selenide anion and its applicability to SN2 - type ester cleavages (1977) (50)
Two Domains That Control Prefusion Stability and Transport Competence of the Measles Virus Fusion Protein (2006) (49)
Stereoselectivity of induction of the retinoblastoma gene product (pRb) dephosphorylation by D-erythro-sphingosine supports a role for pRb in growth suppression by sphingosine. (1995) (49)
Enigmol: A Novel Sphingolipid Analogue with Anticancer Activity against Cancer Cell Lines and In vivo Models for Intestinal and Prostate Cancer (2011) (48)
Pharmacokinetics and metabolism of racemic 2',3'-dideoxy-5-fluoro-3'-thiacytidine in rhesus monkeys (1992) (47)
Multiple Anticancer Activities of EF24, a Novel Curcumin Analog, on Human Ovarian Carcinoma Cells (2010) (47)
Discovery of tetrahydroisoquinoline-based CXCR4 antagonists. (2013) (47)
Synthesis and biological evaluation of 2',3'-didehydro-2',3'- dideoxy-5-fluorocytidine (D4FC) analogues: discovery of carbocyclic nucleoside triphosphates with potent inhibitory activity against HIV-1 reverse transcriptase. (1999) (46)
Diastereoselective addition of chlorotitanium enolate of N-acyl thiazolidinethione to O-methyl oximes: A novel, stereoselective synthesis of α, β-disubstituted β-amino carbonyl compounds via chiral auxiliary mediated azetine formation (2003) (46)
The Ecstasy and Agony of Assay Interference Compounds. (2017) (44)
Mapping the Binding of GluN2B-Selective N-Methyl-d-aspartate Receptor Negative Allosteric Modulators (2012) (44)
Cellular pharmacology and biological activity of 5-carboranyl-2'-deoxyuridine. (1994) (43)
Autophagy and Apoptosis in Hepatocellular Carcinoma Induced by EF25-(GSH)2: A Novel Curcumin Analog (2014) (43)
Infectious amplification of wild-type human immunodeficiency virus from patients' lymphocytes and modulation by reverse transcriptase inhibitors in vitro (1993) (42)
Synthesis and structure activity relationship of tetrahydroisoquinoline-based potentiators of GluN2C and GluN2D containing N-methyl-D-aspartate receptors. (2013) (41)
3-Alkylfurans as useful synthetic equivalents for substituted δ2-butenolides (1983) (41)
Design, Synthesis, and Structure–Activity Relationship of a Novel Series of GluN2C-Selective Potentiators (2014) (40)
Biochemical and mechanistic basis for the activity of nucleoside analogue inhibitors of HIV reverse transcriptase. (2004) (39)
Structure-activity relationships and pharmacophore model of a noncompetitive pyrazoline containing class of GluN2C/GluN2D selective antagonists. (2013) (37)
Selenium in Organic Synthesis (1986) (37)
Stereoselective hydrogen-transfer reactions involving acyclic radicals. A study of radical conformations using semiempirical calculations (1992) (37)
Dynamics and fluidity of amyloid fibrils: a model of fibrous protein aggregates. (2002) (37)
Directed evolution of an orthogonal nucleoside analog kinase via fluorescence-activated cell sorting (2009) (36)
The 5'-triphosphates of the (-) and (+) enantiomers of cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolane-5-yl]cytosine equally inhibit human immunodeficiency virus type 1 reverse transcriptase (1993) (36)
Non-nucleoside inhibitors of the measles virus RNA-dependent RNA polymerase: synthesis, structure-activity relationships, and pharmacokinetics. (2012) (36)
Pharmacokinetics, oral bioavailability, and metabolic disposition in rats of (-)-cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl] cytosine, a nucleoside analog active against human immunodeficiency virus and hepatitis B virus (1993) (36)
Pyrazolo-Piperidines Exhibit Dual Inhibition of CCR5/CXCR4 HIV Entry and Reverse Transcriptase. (2015) (35)
1-Deoxy-5-hydroxysphingolipids as new anticancer principles: an efficient procedure for stereoselective syntheses of 2-amino-3,5-diols. (2005) (35)
NMDA receptor modulators: an updated patent review (2013 – 2014) (2014) (34)
Recent advances in the development of HBV capsid assembly modulators. (2019) (33)
Development and screening of water-soluble analogues of progesterone and allopregnanolone in models of brain injury. (2009) (32)
Nitrogen Glycosylation Reactions Involving Pyrimidine and Purine Nucleoside Bases with Furanoside Sugars (1995) (32)
Simple, inexpensive procedure for the large-scale production of alkyl quinones (1983) (32)
A Novel Negative Allosteric Modulator Selective for GluN2C/2D-Containing NMDA Receptors Inhibits Synaptic Transmission in Hippocampal Interneurons. (2017) (32)
The Ecstasy and Agony of Assay Interference Compounds. (2017) (32)
Use of magnesium cation in aldol additions - a convenient method for achieving anti-aldol selectivity (1991) (31)
Novel Cyclopropyl-Indole Derivatives as HIV Non-Nucleoside Reverse Transcriptase Inhibitors. (2012) (31)
Synthesis, structural activity-relationships, and biological evaluation of novel amide-based allosteric binding site antagonists in NR1A/NR2B N-methyl-D-aspartate receptors. (2009) (31)
Monocarbonyl curcumin analogues: heterocyclic pleiotropic kinase inhibitors that mediate anticancer properties. (2013) (31)
CCR5 receptor antagonists in preclinical to phase II clinical development for treatment of HIV (2016) (30)
Ligand-assisted nucleophilic additions. Control of site and face attack of nucleophiles on 4-oxido enones (1988) (30)
Targeting tissue factor-expressing tumor angiogenesis and tumors with EF24 conjugated to factor VIIa. (2008) (30)
Recent patents regarding the discovery of small molecule CXCR4 antagonists (2009) (30)
Structural elements of a pH-sensitive inhibitor binding site in NMDA receptors (2019) (30)
A structurally derived model of subunit‐dependent NMDA receptor function (2018) (30)
Nucleophilic ring opening of lactones via SN2-type reaction with uncomplexed phenyl selenide anion (1978) (29)
A Real-Time Method for Measuring cAMP Production Modulated by Gαi/o-Coupled Metabotropic Glutamate Receptors (2014) (29)
Origins of regio- and stereoselectivity in additions of phenylselenenyl chloride to allylic alcohols and the applicability of these additions to a simple 1,3-enone transposition sequence (1982) (28)
Stereoselective synthesis of quaternary center bearing azetines and their beta-amino acid derivatives. (2008) (27)
MECHANISTIC ASPECTS OF THE LIGAND-ASSISTED NUCLEOPHILIC ADDITION REACTION (1990) (27)
Enantiomeric propanolamines as selective N-methyl-D-aspartate 2B receptor antagonists. (2008) (27)
Transition-state pliability in nitrogen-to-nitrogen proton transfer (1983) (27)
Synthesis of sphingosine and sphingoid bases. (2000) (26)
Novel synthesis and biological evaluation of enigmols as therapeutic agents for treating prostate cancer. (2011) (26)
An NMDAR positive and negative allosteric modulator series share a binding site and are interconverted by methyl groups (2018) (26)
Human acid beta-glucosidase: use of sphingosyl and N-alkyl-glucosylamine inhibitors to investigate the properties of the active site. (1990) (25)
Diels-Alder reactions involving cross-conjugated dienones. Effects of substitution on reactivity (1981) (25)
Inhibition of skin carcinomas but not papillomas by sphingosine, N-methylsphingosine, and N-acetylsphingosine. (1998) (25)
Discovery of aminoquinolines as a new class of potent inhibitors of heat shock protein 90 (Hsp90): Synthesis, biology, and molecular modeling. (2008) (24)
Synthesis of C-arabinofuranosyl compounds. Phosphonate and carboxylate isosteres of d-arabinose 1,5-bisphosphate (1987) (24)
Highly diastereoselective aldol reactions of chiral methyl ketones (1993) (24)
Pyridinium dichromate-induced 1,3-oxidative rearrangements of enynols (1987) (23)
Phosphatidyl-2',3'-dideoxy-3'-thiacytidine: synthesis and antiviral activity in hepatitis B-and HIV-1-infected cells. (1995) (23)
Discovery and Development of the Anti-Human Immunodeficiency Virus Drug, Emtricitabine (Emtriva, FTC). (2016) (23)
Cyclization protocols for controlling the glycosidic stereochemistry of nucleosides. Application to the synthesis of the antiviral agent 3'-azido-3'-deoxythymidine (AZT) (1991) (23)
Complementary Facial Selectivity in Conjugate Additions to γ-Hydroxyenones (1992) (23)
Episulfonium ions may not be the stereodeterminants in glycosylations of 2-thioalkyl pyranosides (1993) (23)
The synthesis and anti-hiv activity of pyrimidine dioxolanyl nucleosides (1993) (22)
Photoelectron spectra of alkyl aryl selenides. Electronic and steric factors in the observation of rotamers (1981) (22)
Discovery of Tetrahydroisoquinoline-Containing CXCR4 Antagonists with Improved in Vitro ADMET Properties. (2018) (22)
Synthesis and Metabolic Studies of Host Directed Inhibitors for Anti Viral Therapy. (2013) (22)
An efficient synthesis of 3′-fluoro-3′-deoxythymidene (FLT) (1992) (22)
NMDA receptor channel gating control by the pre-M1 helix (2020) (21)
A two-step chemical and circular dichroic method for assigning the absolute configurations of sphingosines (1995) (21)
Targeting tissue factor-expressing tumor angiogenesis and tumors with EF24 conjugated to factor VIIa (2008) (21)
Synthetic applications of 2-phenylselenenylenones—III (1985) (21)
Anti‐HIV Small‐Molecule Binding in the Peptide Subpocket of the CXCR4:CVX15 Crystal Structure (2014) (21)
A synthesis of the abietane diterpenoid quinone (±)-royleanone via maleoylcobalt technology. (1990) (21)
Design, Synthesis, and Pharmacological Evaluation of Second-Generation Tetrahydroisoquinoline-Based CXCR4 Antagonists with Favorable ADME Properties. (2018) (21)
Synthetic applications of phenyltrimethylsilylselenide (1978) (20)
Regulation of sphingosine-activated protein kinases: selectivity of activation by sphingoid bases and inhibition by non-esterified fatty acids. (1993) (20)
Molecular aggregation and its applicability to synthesis. The Diels-Alder reaction (1988) (20)
Diastereoselective sulfenylation reactions employing N-phenylthio lactams under nonbasic conditions (1992) (20)
A General Synthesis of 2-Phenylselenenylenones. The Reaction of Unsaturated Ketones with a Phenylselenenyl Chloride/Pyridine Complex (1980) (19)
Stereocontrolled glycosylations via additions of sulfur electrophiles to glycals (1993) (19)
Calculated conformer energies for organic molecules with multiple polar functionalities are method dependent: Taxol (case study) (2001) (19)
Pharmacokinetics of the Antiviral Agent β-d-2′,3′-Didehydro-2′,3′-Dideoxy-5-Fluorocytidine in Rhesus Monkeys (1999) (19)
Small molecule and peptide-based CXCR4 modulators as therapeutic agents. A patent review for the period from 2010 to 2018 (2019) (19)
Design and synthesis of C6-C8 bridged epothilone A. (2008) (18)
Biased modulators of NMDA receptors control channel opening and ion selectivity (2019) (18)
In situ Complexation Directs the Stereochemistry of N‐Glycosylation in the Synthesis of Oxathiolanyl and Dioxolanyl Nucleoside Analogues. (1992) (18)
Discovery of novel N-aryl piperazine CXCR4 antagonists. (2015) (18)
Synthesis and evaluation of 2'-substituted cyclobutyl nucleosides and nucleotides as potential anti-HIV agents. (2007) (18)
Bioactive Properties of Sphingosine and Structurally Related Compounds (1996) (18)
Fluorimetric studies of protein kinase C interactions with phospholipids. (1989) (17)
A diastereoselective synthesis of (2S, 3R, 4S)-2-amino-1-cyclohexyl-6-methylheptane-3,4-diol, the Abbott aminodiol☆ (1996) (17)
Synthetic applications of 2-phenylselenenyl enones. Selective formation of exocyclic or endocyclic enones from a common intermediate (1980) (17)
Reactions involving selenium metal as an electrophile. The enolate - selenolate transformation (1980) (17)
New probes for electron-transfer processes. Evidence supporting the single-electron-transfer mechanism in additions of carbanions to dienones (1983) (17)
Based-induced rearrangements of .alpha.-phenylselenenyl ketones (1982) (17)
Phosphonosilylations of cyclic enones (1982) (17)
Enantioselective synthesis of the carbocyclic nucleoside (-)-abacavir. (2012) (16)
Triene Cyclizations. The Total Synthesis of Pallescensin A (1987) (16)
Bimodal Regulation of Ceramidase by Interleukin-1 b IMPLICATIONS FOR THE REGULATION OF CYTOCHROME P 450 2 C 11 ( CYP 2 C 11 ) * (1997) (16)
Acetylide Additions to Enediones. Regioselectivity Based on Stereoelectronic Control. (1985) (16)
SYNTHETIC APPLICATIONS OF 2-PHENYLSELENENYLENONES. 2. SYNTHESIS OF DIHYDROJASMONE AND CIS-JASMONE (1981) (16)
Reactions involving selenium metal as an electrophile. 2. A general procedure for the preparation of unsaturated β-dicarbonyl compounds (1981) (16)
Discovery of a Fluorinated Enigmol Analog with Enhanced in Vivo Pharmacokinetic and Anti-Tumor Properties. (2016) (16)
Absolute Configuration of the Antiviral Agent (−)-cis-5-Fluoro-1-[2-Hydroxymethyl)-1,3-Oxathiolan-5-yl]Cytosine (1993) (16)
Synthetic applications of phenylselenenyl chloride additions. A simple 1,3-enone transposition sequence (1980) (15)
Aldol reactions of α-(N,N-dibenzylamino) ethyl ketones (1994) (15)
Solvation-controlled diastereofacial selectivity in alkylations of bicyclic lactam enolates (1990) (15)
Pharmacokinetics of 5-carboranyl-2'-deoxyuridine in rats. (1994) (15)
Synthesis of 1-deoxysphingosine derivatives with conformationally restricted pyrrolidinediol head groups. (2006) (15)
The GluN2B‐Glu413Gly NMDA receptor variant arising from a de novo GRIN2B mutation promotes ligand‐unbinding and domain opening (2018) (15)
Computational studies of transition metal selectivity of octapeptide repeat region of prion protein (PrP). (2010) (14)
SELECTIVE REACTIONS OF CARBANIONS WITH P-QUINONES. THE AGGREGATE MODEL (1981) (14)
Potent SARS-CoV-2 Direct-Acting Antivirals Provide an Important Complement to COVID-19 Vaccines (2021) (14)
Influences of sphingosine on two-stage skin tumorigenesis in Sencar mice. (1992) (14)
An efficient asymmetric synthesis of Enigmols (1-deoxy-5- hydroxysphingoid bases), an important class of bioactive lipid modulators (2010) (13)
Chloride is an Agonist of Group II and III Metabotropic Glutamate Receptors (2015) (13)
Diastereoselective synthesis of the key lactone intermediate for the preparation of hydroxyethylene dipeptide isosteres (1994) (13)
The reaction of β,γ-unsaturated acids with phenylselenenyl chloride.: Decarboxylative elimination vs phenylselenolactonization. (1979) (13)
An examination of the synthetic utility of phenylselenenyl chloride additions to olefins (1979) (13)
Asymmetric synthesis of host-directed inhibitors of myxoviruses (2013) (13)
Remote asymmetric induction in organocopper conjugate additions to 3-ketoacrylates (1996) (12)
Evaluating the neurotherapeutic potential of a water-soluble progesterone analog after traumatic brain injury in rats (2016) (12)
Negative allosteric modulation of GluN1/GluN3 NMDA receptors (2020) (12)
Tumor Angiogenesis Therapy Using Targeted Delivery of Paclitaxel to the Vasculature of Breast Cancer Metastases (2014) (12)
Aryl Substituted Benzimidazolones as Potent HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors. (2019) (12)
Opening of tartrate acetals using dialkylboron bromide: evidence for stereoselectivity downstream from ring fission. (2003) (12)
Stereocontrolled synthesis of β-2′-deoxypyrimidine nucleosides via intramolecular glycosylations (1997) (12)
The Ecstasy and Agony of Assay Interference Compounds. (2017) (12)
The case favoring direct C-alkylation of heteroatom-substituted enolates (1988) (12)
Surprisingly high diastereoselection in the aldol reactions of sodium enolates of α-amino methyl ketones (1994) (12)
Water-soluble progesterone analogues are effective, injectable treatments in animal models of traumatic brain injury. (2012) (12)
Synthesis of Novel Tetrahydroisoquinoline CXCR4 Antagonists with Rigidified Side-Chains. (2018) (11)
The Structure-Activity Relationship of a Tetrahydroisoquinoline Class of N-Methyl-d-Aspartate Receptor Modulators that Potentiates GluN2B-Containing N-Methyl-d-Aspartate Receptors. (2017) (11)
Pharmacokinetics of 2',3'-dideoxy-5-fluoro-3'-thiacytidine in rats. (1994) (11)
REVERSAL OF STEREOSPECIFICITY DURING ALLYLIC HYDROPEROXIDATION OF 3-NORCARENE AND BICYCLO(4.2.0)OCT-3-ENE DERIVATIVES ARISING FROM STRUCTURALLY ENFORCED QUENCHING OF SINGLET OXYGEN BY THE HYDRAZIDE FUNCTIONALITY (1976) (11)
Synthesis and SAR of 1,2,3,4-Tetrahydroisoquinoline-Based CXCR4 Antagonists. (2018) (11)
Structural analysis of CXCR4 - Antagonist interactions using saturation-transfer double-difference NMR. (2015) (11)
Inhibition of breast cancer metastasis to the lungs with UBS109 (2018) (10)
A novel class of negative allosteric modulators of NMDA receptor function. (2015) (10)
Comparison of collisional activation spectra of some positive ions produced both by charge reversal of negative ions and by decomposition of positive ions (1982) (10)
In Vitro Metabolic Stability and in Vivo Biodistribution of 3-Methyl-4-furoxancarbaldehyde Using PET Imaging in Rats. (2016) (10)
Trajectories of proton transfer reactions. Experimental determination of the magnitude of primary deuterium isotope effects for proton-transfers occuring at acute angles (1988) (10)
A General Synthetic Method of 5-Carboranyluracil Nucleosides with Potential Antiviral Activity and use in Neutron Capture Therapy (1997) (9)
Synthesis of fluorescent nucleoside analogs as probes for 2'-deoxyribonucleoside kinases. (2010) (9)
Frontier molecular orbital basis for the structurally dependent regiospecific reactions of singlet (1Δg) oxygen with polyolefins (1976) (9)
Adamantane and nipecotic acid derivatives as novel β-Turn mimics (1994) (9)
C6-C8 bridged epothilones: consequences of installing a conformational lock at the edge of the macrocycle. (2011) (9)
Synthesis, anti-human immunodeficiency virus, and anti-hepatitis B virus activity of pyrimidine oxathiolane nucleosides (1993) (9)
Reduction Sensitive Lipid Conjugates of Tenofovir: Synthesis, Stability, and Antiviral Activity. (2016) (8)
The Discovery of Dihydropyrrolo[1,2-a]pyrazin-3(4H)-one-Based Second-Generation GluN2C- and GluN2D-Selective Positive Allosteric Modulators (PAMs) of the N-Methyl-D-Aspartate (NMDA) Receptor. (2020) (8)
A Machine Learning Approach for Predicting HIV Reverse Transcriptase Mutation Susceptibility of Biologically Active Compounds (2018) (8)
Small molecule CXCR4 antagonists block the HIV-1 Nef/CXCR4 axis and selectively initiate the apoptotic program in breast cancer cells (2018) (8)
Distinct GluN1 and GluN2 Structural Determinants for Subunit-Selective Positive Allosteric Modulation of N-Methyl-d-aspartate Receptors. (2020) (8)
A Facially-Selective Protonation Controls the Stereochemistry of a Key Intermediate in the Synthesis of 1.beta.-Methylcarbapenems (1994) (8)
Synthesis of enantiomerically pure D-FDOC, an anti-HIV agent. (2004) (8)
Pharmacology and Pharmacokinetics of the Antiviral Agent β-d-2′,3′-Dideoxy-3′-Oxa-5-Fluorocytidine in Cells and Rhesus Monkeys (2005) (8)
Next-Generation Reduction Sensitive Lipid Conjugates of Tenofovir: Antiviral Activity and Mechanism of Release. (2016) (7)
Some observations on the relative reactivities of .alpha.-enones of oxanes and cyclohexanes (1986) (7)
Reactions of N-aryl nitrogen oxides. 1. Selective ortho chlorination in the reactions of aryl nitrones and amine oxides with thionyl chloride or phosgene (1974) (7)
Discovery of N-Alkyl Piperazine Side Chain Based CXCR4 Antagonists with Improved Drug-like Properties. (2018) (7)
Correction to Synthesis and Structure Activity Relationship of Tetrahydroisoquinoline-Based Potentiators of GluN2C and GluN2D Containing N-Methyl-d-aspartate Receptors. (2014) (7)
Reactions of N-aryl nitrogen oxides. 2. Reaction of N-aryl nitrones with oxalyl chloride (1974) (7)
A new MODEL parameter set for .beta.-lactams (1989) (7)
Ceramide Synthase and Ceramidases in the Regulation of Sphingoid Base Metabolism (1997) (7)
Identification of Non-Nucleoside Inhibitors of the Respiratory Syncytial Virus Polymerase Complex. (2017) (7)
The Ecstasy and Agony of Assay Interference Compounds. (2017) (7)
Sphingolipid analogues inhibit development of malaria parasites. (2012) (7)
Regioselective Fluoroalkoxylation And Polyfluoroalkoxylation Of Aromatic And Heteroaromatic Polyhalides (1985) (7)
Rearrangement of a-Phenylselenenylketones (1986) (7)
Suppression of racemization during the diastereoselective C-3 functionalization of 5-hydroxymethyl-2-phenylthio-2-(5H)-furanones (1992) (7)
Pre-steady state kinetic analysis of cyclobutyl derivatives of 2'-deoxyadenosine 5'-triphosphate as inhibitors of HIV-1 reverse transcriptase. (2012) (7)
Total Synthesis of SR 121463 A, a Highly Potent and Selective Vasopressin V2 Receptor Antagonist. (2001) (6)
Synthesis of EF 24-Tripeptide Chloromethyl Ketone : A Novel Curcumin-Related Anticancer Drug Delivery System (2006) (6)
Update to Our Reader, Reviewer, and Author Communities-April 2020. (2020) (6)
AN UNUSUAL STEREOSELECTIVE DECARBOXYLATION : A KEY REACTION TO AN IMPORTANT INTERMEDIATE FOR CARBAPENEM ANTIBIOTICS (1995) (6)
The Ecstasy and Agony of Assay Interference Compounds. (2017) (6)
Electron spectroscopy: ultraviolet excitation (1976) (6)
Amyloid Structure: Models and Theoretical Considerations in Fibrous Aggregates (2002) (6)
Practical synthesis of N-palmitoylsphingomyelin and N-palmitoyldihydrosphingomyelin. (2000) (6)
ω-Functionalized Lipid Prodrugs of HIV NtRTI Tenofovir with Enhanced Pharmacokinetic Properties. (2021) (6)
Confronting Racism in Chemistry Journals. (2020) (6)
Enzyme-Mediated Enantioselective Preparation of Pure Enantiomers of the Antiviral Agent 2′,3′-Dideoxy-5-fluoro-3′-thiacytidine (FTC) (I) and Related Compounds. (1993) (6)
Onium ions are not on the reaction coordinate in the formation of heterocycles via electrophile-induced alkenol cyclizations (1993) (5)
Reaction of aryl nitrones with thionyl chloride or phosgene (1973) (5)
Development of a novel progesterone analog in the treatment of traumatic brain injury (2019) (5)
The 2,2,2-trifluoroethyl ligand: a structural "reporter" group for its carbanion character in organometallic compounds (1985) (5)
Visualizing cancer and response to therapy in vivo using Cy5.5-labeled factor VIIa and anti-tissue factor antibody (2015) (5)
Accelerated Discovery of Potent Fusion Inhibitors for Respiratory Syncytial Virus. (2020) (5)
One-pot transformation of esters to analytically pure ketones: methodology and application in process development (2015) (5)
Electron Spectroscopy: Ultraviolet and X-Ray Excitation. (1978) (5)
A uniquely accessible route to the diastereoselective synthesis of azetine derivatives (2004) (5)
Lipids as hormones and second messengers (1991) (4)
Identification of Ammonium Ion and 2,6-Bis(ω-aminobutyl)- 3,5-diiminopiperazine as Endogenous Factors That Account for the “Burst” of Sphingosine upon Changing the Medium of J774 Cells in Culture* (1999) (4)
Tetrahydroisoquinoline CXCR4 Antagonists Adopt a Hybrid Binding Mode within the Peptide Subpocket of the CXCR4 Receptor. (2018) (4)
Endoperoxidation of conformationally fixed norcaradienes by singlet oxygen. Frontier molecular orbital basis for the operability of 1O2 quenching by hydrazides (1976) (4)
Diastereoselective addition of chlorotitanium enolates of N-acyl thiazolidinethione to activated imines — A novel synthesis of β-lactams (2006) (4)
The Thermal Decomposition of Alkoxycarbonyl Thiocyanates and Isothiocyanates (1975) (4)
A Glutamate N-Methyl-d-Aspartate (NMDA) Receptor Subunit 2B–Selective Inhibitor of NMDA Receptor Function with Enhanced Potency at Acidic pH and Oral Bioavailability for Clinical Use (2021) (4)
Stereoselectivity of Electrophile-Promoted Cyclizations of γ-Hydroxyalkenes. An Investigation of Carbohydrate-Derived and Model Substrates. (1988) (4)
Reactions involving selenium metal as an electrophile: Scope and limitations of the enolate‐selenolate transformation (1990) (4)
Accelerated Discovery of Novel Ponatinib Analogs with Improved Properties for the Treatment of Parkinson's Disease. (2020) (4)
Mechanism for non-competitive inhibition by novel GluN2C/D NMDA receptor subunit-selective modulators (2011) (4)
Spiroconjugation involving sulfur 3p atomic orbitals (1976) (4)
The Ecstasy and Agony of Assay Interference Compounds. (2017) (4)
Confronting Racism in Chemistry Journals. (2020) (3)
Preclinical and clinical development of the anti-HIV, anti-HBV oxathiolane nucleoside analog emtricitabine (2003) (3)
Anticancer effects of monocarbonyl analogs of curcumin: oxidative stress, nuclear translocation and modulation of AP-1 and NF-κB (2015) (3)
Synthesis and Biological Evaluation of 5'-C-Methyl Nucleotide Prodrugs for Treating HCV Infections. (2020) (3)
Coal liquefaction in a fluorocarbon medium. 1. Nitrogen compounds as hydrogen transfer agents (1986) (3)
Confronting Racism in Chemistry Journals. (2020) (3)
North-South Collaborations to Promote Health Innovations in Africa (2018) (3)
Academic Drug Development: The DRIVE Model. (2018) (3)
Group A streptococcus inhibitors by high-throughput virtual screening. (2014) (3)
Advances in molecular modeling : a research annual (1988) (3)
Confronting Racism in Chemistry Journals. (2020) (3)
Radiosensitization of glioma cells with the curcumin analogs EF24 and EF31 (2008) (3)
Thiazolidine‐2‐thione Directed Diastereoselective Addition of Chlorotitanium Enolates to Aldimines. (2003) (3)
Synthesis, Antiviral Activity, Cytotoxicity, and Cellular Pharmacology of 5-Carboranyl-Pyrimidine Nucleosides (1993) (3)
Sphingolipids as regulators of cellular growth, differentiation, and behavior (1996) (3)
Some Observations on the Relative Reactivities of α-Enones of Oxanes and Cyclohexanes. (1986) (3)
Addition Reactions with Formation of Carbon–Sulfur or Carbon–Selenium Bonds (1991) (3)
Role of Macroautophagy in Anti‐Cancer Effects of the Novel Sphingolipid, Enigmol (2015) (2)
Confronting Racism in Chemistry Journals. (2020) (2)
Diastereoselective Addition of Chlorotitanium Enolate of N-Acyl Thiazolidinethione to O-Methyl Oximes: A Novel, Stereoselective Synthesis of α,β-Disubstituted β-Amino Carbonyl Compounds via Chiral Auxiliary Mediated Azetine Formation. (2003) (2)
Treatment of Isografted 9 L Rat Brain Tumors with b-5o-Carboranyl-2 *-Deoxyuridine Neutron Capture Therapy 1 (2000) (2)
The Negative Allosteric Modulator EU1794-4 Reduces Single-Channel Conductance and Ca2+ Permeability of GluN1/GluN2A N-Methyl-d-Aspartate Receptors (2021) (2)
Thermal decomposition of phosphorothioates (1970) (2)
Synthesis and Antiviral Activity of a Series of 2′-C-Methyl-4′-thionucleoside Monophosphate Prodrugs (2020) (2)
An Efficient Synthesis of 3′‐Fluoro‐3′‐deoxythymidine (FLT). (1993) (2)
Update to Our Reader, Reviewer, and Author Communities—April 2020 (2020) (2)
3-Alkylfurans as Useful Synthetic Equivalents for Substituted Δ2-Butenolides. (1984) (2)
Synthesis and Biological Evaluation of 2′,3′-Didehydro-2′,3′-dideoxy-5- fluorocytidine (D4FC) Analogues: Discovery of Carbocyclic Nucleoside Triphosphates with Potent Inhibitory Activity against HIV-1 Reverse Transcriptase1 (1999) (2)
Confronting Racism in Chemistry Journals. (2020) (2)
A General Method for Controlling Glycosylation Stereochemistry in the Synthesis of 2′-Deoxyribose Nucleosides. (1991) (2)
Confronting Racism in Chemistry Journals. (2020) (1)
The reaction of N-aryl nitrones with dichloroketene: A new synthesis of isatins (1978) (1)
Amino-Heterocycle Tetrahydroisoquinoline CXCR4 Antagonists with Improved ADME Profiles via Late-Stage Buchwald Couplings. (2021) (1)
Method and compositions of synthesis bch-189 and related compounds. (1991) (1)
Stereoselective Synthesis of Quaternary Center Bearing Azetines and Their β-Amino Acid Derivatives. (2008) (1)
New Drug Modalities in Medicinal Chemistry, Pharmacology, and Translational Science: Joint Virtual Special Issue by Journal of Medicinal Chemistry, ACS Medicinal Chemistry Letters, and ACS Pharmacology & Translational Science. (2021) (1)
Confronting Racism in Chemistry Journals. (2020) (1)
330 FLUORINATION OF ENIGMOL IMPROVES TISSUE UPTAKE AND AFFECTS IN VIVOPROSTATE CANCER EFFICACY (2013) (1)
Update to Our Reader, Reviewer, and Author Communities-April 2020. (2020) (1)
Stereocontrolled Synthesis of β-2′-Deoxypyrimidine Nucleosides via Intramolecular Glycosylations. (1997) (1)
Journal of Medicinal Chemistry/ACS Medicinal Chemistry Letters/Division of Medicinal Chemistry Joint Portoghese Lectureship Awards: CALL FOR NOMINATIONS. (2022) (1)
New Drug Modalities in Medicinal Chemistry, Pharmacology, and Translational Science: Joint Virtual Special Issue by Journal of Medicinal Chemistry, ACS Medicinal Chemistry Letters, and ACS Pharmacology & Translational Science. (2021) (1)
Aldol Reactions of α‐(N,N‐Dibenzylamino) Ethyl Ketones. (1995) (1)
A General Synthetic Method of 5‐Carboranyluracil Nucleosides with Potential Antiviral Activity and Use in Neutron Capture Therapy. (1998) (1)
Confronting Racism in Chemistry Journals. (2020) (1)
A GluN2B-selective inhibitor of NMDA receptor function with enhanced potency at acidic pH and oral bioavailability for clinical use (2021) (1)
Update to Our Reader, Reviewer, and Author Communities-April 2020. (2020) (1)
ENIGMOL (2-AMINO-3,5-DIHYDROXYOCTADECANE [2S, 3S, 5S]) IS A NOVEL SPHINGOLIPID ANALOG THAT SHOWS A PROMISING EFFECT IN THE TREATMENT OF PROSTATE CANCER (2008) (1)
Update to Our Reader, Reviewer, and Author Communities-April 2020. (2020) (1)
Vimentin: A Novel Chemopreventive Target for Breast Cancer Metastasis. (2009) (1)
Di-aryl Sulfonamide Motif Adds π-Stacking Bulk in Negative Allosteric Modulators of the NMDA Receptor. (2019) (1)
Synthesis and Evaluation of Novel Tetrahydronaphthyridine CXCR4 Antagonists with Improved Drug-like Profiles. (2022) (1)
Thiazolidine-2-thione Directed Diastereoselective Addition of Chlorotitanium Enolates to Aldimines (2002) (1)
A Diastereoselective Synthesis of (2S,3R,4S)‐2‐Amino‐1‐cyclohexyl‐6‐ methylheptane‐3,4‐diol, the Abbott Aminodiol. (1996) (0)
A process for the beta-2-hydroxymethyl-5- (5-fluoro-cytosin-1-yl) -1,3-oxathiolane (2006) (0)
Suppression of Early Markers of Colon Carcinogenesis-d-Glucuronide : Synthesis , Digestion , and β Ceramide-Updated (1999) (0)
REACTIONS INVOLVING SELENIUM METAL AS AN ELECTROPHILE. THE ENOLATE-SELENOLATE TRANSFORMATION (1981) (0)
Reaction of coal with 1,2,3,4-tetrahydroquinoline in a perfluorocarbon medium (1987) (0)
Stereoselective Hydrogen Transfer Reactions Involving Acyclic Radicals. Tandem Substituted Tetrahydrofuran Formation and Stereoselective Reduction: Synthesis of the C17-C22 Subunit of Ionomycin. (1994) (0)
Method of useful beta-2-hydroxymethyl-5- (5-fluorocytosin-1-yl) preparing a therapeutically -1,3-oxathiolane (2005) (0)
Giving Credit Where Credit Is Due: Properly Citing Relevant Prior Art. (2021) (0)
Recent Reviews. 45 (1997) (0)
Diastereoselective Synthesis of the Key Lactone Intermediate (VI) for the Preparation of Hydroxyethylene Dipeptide Isosteres. (2010) (0)
Triene Cyclizations. The Total Synthesis of Pallescensin A. (1988) (0)
Enhanced nucleophilic displacement in phosphinite esters (1970) (0)
Suppression of Racemization During the Diastereoselective C-3 Functionalization of 5-Hydroxymethyl-2-phenylthio-2-(5H)-furanones. (1993) (0)
REACTIONS INVOLVING SELENIUM METAL AS AN ELECTROPHILE. 2. A GENERAL PROCEDURE E FOR THE PREPARATION OF UNSATURATED β-DICARBONYL COMPOUNDS (1981) (0)
111. The curcumin analog, UBS-109 decreases peripheral expression of LPS-induced inflammatory cytokines (2008) (0)
Confronting Racism in Chemistry Journals. (2020) (0)
Update to Our Reader, Reviewer, and Author Communities-April 2020. (2020) (0)
Highly Diastereoselective Aldol Reactions of Chiral Methyl Ketones. (1993) (0)
Virally Encoded Polymerases as Targets for Chemotherapy: Application to HIV and HBV (2002) (0)
Analogues de circumine destines au traitement du cancer (2000) (0)
A process for preparing diphenylacetylener (1988) (0)
REACTIONS OF N-ARYL NITROGEN OXIDES PART 1, SELECTIVE ORTHO CHLORINATION IN THE REACTIONS OF ARYL NITRONES AND AMINE OXIDES WITH THIONYL CHLORIDE OR PHOSGENE (1974) (0)
Subcellular Localization of a Boronated Nucleoside Using Ion Microscopy (1996) (0)
Introductory Editorial for ACS Medicinal Chemistry Letters. (2010) (0)
Insights into the Modulation of Ceramide Metabolism by Naturally Occurring and Synthetic Sphingolipid Analogs as Monitored by Electrospray Tandem Mass Spectrometry (2013) (0)
Confronting Racism in Chemistry Journals. (2020) (0)
Update to Our Reader, Reviewer, and Author Communities - April 2020 (2020) (0)
Synthesis and evaluation of 2 0-substituted cyclobutyl nucleosides and nucleotides as potential anti-HIV agents (2007) (0)
SYNTHETIC APPLICATIONS OF PHENYL(TRIMETHYLSILYL)SELENIDE (1979) (0)
Inhibitor That Shows Antitumor Activity The Development of a Selective Cyclin-Dependent Kinase (2009) (0)
Triptolide analogs autoimmune crane units for treatment of inflammation and (2001) (0)
Confronting Racism in Chemistry Journals. (2020) (0)
THE REACTION OF ARYL NITRONES WITH THIONYL CHLORIDE OR PHOSGENE (1974) (0)
Antiviral 2-hydroxymethyl-5- (5-fluorcytosin-1-yl) -1,3-oxatiolan and also its resolution (1993) (0)
Confronting Racism in Chemistry Journals. (2020) (0)
Diastereoselective addition of chlorotitanium enolate of N-acyl thiazolidinethione to O-methyl oximes: a novel, stereoselective synthesis of alpha,beta-disubstituted beta-amino carbonyl compounds via chiral auxiliary mediated azetine formation. (2003) (0)
Sphingolipid derivatives and methods for their use (1999) (0)
Use of the Magnesium Cation in Aldol Additions. A Convenient Method for Achieving Anti-Aldol Selectivity. (1992) (0)
Synthesis of Sphingosine and Sphingoid Bases (2000) (0)
Confronting Racism in Chemistry Journals. (2020) (0)
Krumm Against a Lethal Morbillivirus Infection in a Large Animal Model An Orally Available , Small-Molecule Polymerase Inhibitor Shows Efficacy (2014) (0)
Trajectories of Proton-Transfer Reactions. Experimental Determination of the Magnitude of Primary Deuterium Isotope Effects for Proton Transfers Occurring at Acute Angles. (1988) (0)
Update to Our Reader, Reviewer, and Author Communities-April 2020. (2020) (0)
Update to Our Reader, Reviewer, and Author Communities-April 2020. (2020) (0)
Confronting Racism in Chemistry Journals. (2020) (0)
Method 2 ', 3'-dideoxy-3'-thia-pyrimidine nucleoside comprising a mixture of isomers for the preparation of (2005) (0)
A process for the production of 1,3-oxathiolanes nucleosides (1999) (0)
Episulfonium Ions May Not be the Stereo‐Determinants in Glycosidations of 2‐Thioalkyl Pyranosides (1996) (0)
Update to Our Reader, Reviewer, and Author Communities-April 2020. (2020) (0)
Update to Our Reader, Reviewer, and Author Communities-April 2020. (2020) (0)
Confronting Racism in Chemistry Journals (2020) (0)
Update to Our Reader, Reviewer, and Author Communities-April 2020. (2020) (0)
Update to Our Reader, Reviewer, and Author Communities-April 2020. (2020) (0)
Confronting Racism in Chemistry Journals (2020) (0)
Prospective evaluation and success of a machine learning hit-to-lead drug development program against phosphatidylinositol 3-kinase α (2020) (0)
Synthetic Applications of 2-Phenylselenenylenones. Part 3. An Overview (1986) (0)
Recent Reviews. 38 (1995) (0)
Virtual Special Issue: Epigenetics 2022. (2022) (0)
A Facially-Selective Protonation Controls the Stereochemistry of a Key Intermediate in the Synthesis of 1β-Methylcarbapenems. (1994) (0)
Giving Credit Where Credit Is Due: Properly Citing Relevant Prior Art. (2021) (0)
Recent Reviews. 41. (1996) (0)
The Synthesis and anti‐HIV Activity of Pyrimidine Dioxolanyl Nucleosides. (1993) (0)
Update to Our Reader, Reviewer, and Author Communities—April 2020 (2020) (0)
Abstract B106: Inhibition of IKKb and NFκB signaling by a novel curcumin analogue (2008) (0)
Diastereoselective Sulfenylation Reactions Employing N‐(Phenylthio) lactams Under Nonbasic Conditions. (1992) (0)
Synthesis and evalution of 2'-substituted cyclobutyl nucleosides and nucleotides as potential anti-HIV agents (0)
Process for the cis-FTC to separate the enantiomers (2003) (0)
Complementary Facial Selectivity in Conjugate Additions to γ‐ Hydroxy Enones. (1992) (0)
Deoxyuridine Neutron Capture Therapy ′-Carboranyl-2 o-5-β Treatment of Isografted 9 L Rat Brain Tumors with Updated (2000) (0)
Coal processing in non-dissolving media (1986) (0)
Update to Our Reader, Reviewer, and Author Communities-April 2020. (2020) (0)
Recent Reviews. 44. (1997) (0)
Confronting Racism in Chemistry Journals. (2020) (0)
A Completely Diastereoselective Electrophilic Fluorination of a Chiral, Noncarbohydrate Sugar Ring Precursor: Application to the Synthesis of Several Novel 2′-Fluoronucleosides. (1998) (0)
Chemical approaches for treating HIV and hepatitis B infections (1997) (0)
Correction to “Design, Synthesis, and Structure–Activity Relationship of a Novel Series of GluN2C-Selective Potentiators” (2015) (0)
Rearrangement of α-Phenylselenenyl Ketones. Part 2. (1987) (0)
Division of Organic Chemistry (1991) (0)
Update to Our Reader, Reviewer, and Author Communities-April 2020. (2020) (0)
A Virtual Collection Focused on Antifungal Drug Discovery. (2022) (0)
Recent Reviews. 43. (1997) (0)
requires production of reactive oxygen species Angiotensin II stimulation of VEGF mRNA translation (2011) (0)
Confronting Racism in Chemistry Journals. (2020) (0)
Update to Our Reader, Reviewer, and Author Communities-April 2020. (2020) (0)
Small molecule CXCR 4 antagonists block the HIV-1 Nef / CXCR 4 axis and selectively initiate the apoptotic program in breast cancer cells (0)
Coal liquefaction in a fluorocarbon medium. II. Kinetics of the 1,2,3,4-tetrahydroquinoline reaction (1986) (0)
Correction to "Accelerated Discovery of Novel Ponatinib Analogs with Improved Properties for the Treatment of Parkinson's Disease". (2020) (0)
A Virtual Collection Focused on Antifungal Drug Discovery. (2022) (0)
One-Pot Transformation of Esters to Analytically Pure Ketones: Methodology and Application in Process Development. (2015) (0)
Confronting Racism in Chemistry Journals. (2020) (0)
vitro. selective inhibitors of hepatitis B virus in beta-2',3'-dideoxycytidine analogs are Pure nucleoside enantiomers of (2014) (0)
Methode de production de nucleosides de 1,3-oxathiolane (1999) (0)
2'-fluoro nucleosides (1999) (0)
The following is a list of selected recently published Expert Opinion articles, related to the content of this issue of Expert Opinion on Therapeutic Targets (2014) (0)
CHAPTER 13:Mechanism of Action of a GluN2C- and GluN2D-Selective NMDA Receptor Positive Allosteric Modulator (2016) (0)
THE REACTION OF β,Γ-UNSATURATED ACIDS WITH PHENYLSELENENYL CHLORIDE. DECARBOXYLATIVE ELIMINATION VS. PHENYLSELENOLACTONIZATION (1980) (0)
THE GENERATION OF UNCOMPLEXED PHENYL SELENIDE ANION AND ITS APPLICABILITY TO SN2-TYPE ESTER CLEAVAGES (1978) (0)
Update to Our Reader, Reviewer, and Author Communities-April 2020. (2020) (0)
A process for the preparation of 1,3-oxathiolane nucleosides (1999) (0)
Update to Our Reader, Reviewer, and Author Communities-April 2020. (2020) (0)
THE REACTION OF N-ARYL NITRONES WITH DICHLOROKETENE- A NEW SYNTHESIS OF ISATINS (1978) (0)
Update to Our Reader, Reviewer, and Author Communities-April 2020. (2020) (0)
Remote Asymmetric Induction in Organocopper Conjugate Additions to 3- Ketoacrylates. (1996) (0)
Innovations in Medicinal Chemistry. (2016) (0)
Lamivudine-Resistant Viral Variants Activity against Zidovudine- and DPC 817: a Cytidine Nucleoside Analog with (2014) (0)
Update to Our Reader, Reviewer, and Author Communities-April 2020. (2020) (0)
ACS Medicinal Chemistry Letters: An Innovation Ten Years in the Making. (2022) (0)
The Case Favoring Direct C-Alkylation of Heteroatom Substituted Enolates. (1989) (0)
Virtual Special Issue: Epigenetics 2022. (2022) (0)
Confronting Racism in Chemistry Journals. (2020) (0)
Analgesics based 4-arilisoindol. (1994) (0)
Synergistic Anticancer Potential of the Combination of the Novel Curcumin Analog EF24 and p38 MAPK Inhibitors (2007) (0)
4-aryl-isoindole analgesics (1995) (0)
Virtual Special Issue: Epigenetics 2022. (2022) (0)
Update to Our Reader, Reviewer, and Author Communities-April 2020. (2020) (0)
1,3-oxathiolane and a process for its preparation (2003) (0)
1438 THE CANCER DRUG ENIGMOL ALTERS SPHINGOLIPID METABOLISM AND REDUCES MACROPHAGE PRESENCE IN PROSTATE TUMORS (2010) (0)
Confronting Racism in Chemistry Journals. (2020) (0)
Cancer and virus leads by HTS, chemical design and SEA data mining. (2009) (0)
Recent Reviews. 46. (1997) (0)
Update to Our Reader, Reviewer, and Author Communities-April 2020. (2020) (0)
Confronting Racism in Chemistry Journals. (2020) (0)
Surprisingly High Diastereoselection in the Aldol Reactions of Sodium Enolates of α‐Amino Methyl Ketones. (1994) (0)
Update to Our Reader, Reviewer, and Author Communities-April 2020. (2020) (0)
Update to Our Reader, Reviewer, and Author Communities-April 2020. (2020) (0)
An Unusual Stereoselective Decarboxylation: A Key Reaction to an Important Intermediate for Carbapenem Antibiotics. (1996) (0)
Confronting Racism in Chemistry Journals. (2020) (0)
Human Immunodeficiency Viruses: Antiretroviral Agents (2008) (0)
Recent Reviews. 40 (1996) (0)
Confronting Racism in Chemistry Journals (2020) (0)
Method of manufacturing 1,3-dioxolane nucleosides and 1,3-oxathiolane (1999) (0)
Stereospecific Synthesis of 1β-Methylcarbapenem Intermediates: Understanding the Selectivity Observed (1996) (0)
Preclinical Development of β-D-5- o -Carboranyl-2′-Deoxyuridine (D-CDU) for the Treatment of Malignant Brain Tumors (2001) (0)
Update to Our Reader, Reviewer, and Author Communities-April 2020. (2020) (0)
Recent Reviews. 42. (1996) (0)
A Virtual Collection Focused on Antifungal Drug Discovery. (2022) (0)
Confronting Racism in Chemistry Journals. (2020) (0)
Confronting Racism in Chemistry Journals. (2020) (0)
Oncology and Biomarkers Summit Inhibition of breast cancer bone metastasis and pancreatic and colon cancer by synthetic curcumin analogs (2017) (0)
Preparation and Reactivity of α-Phenylselenenyl Ethers. (1986) (0)
Activite antivirale et resolution de 2-hydroxymethyl-5-5-fluorocytosine-1-yl-1,3-oxathiolane (1992) (0)
Update to Our Reader, Reviewer, and Author Communities-April 2020. (2020) (0)
Salts and amides of (-) cis 5-Fluoro-2'-deoxy-3'-thiacytidine suitable for the treatment of hepatitis B (1992) (0)
MOL094516 548..560 (2014) (0)
Recent Reviews. 49 (1998) (0)
Update to Our Reader, Reviewer, and Author Communities-April 2020. (2020) (0)
Recent Reviews. 50. (1998) (0)
Free sphingosine in control and stimulated human neutrophils (1987) (0)
Confronting Racism in Chemistry Journals. (2020) (0)
Update to Our Reader, Reviewer, and Author Communities-April 2020. (2020) (0)
Mechanistic Aspects of the Ligand‐Assisted Nucleophilic Addition Reaction. (1991) (0)
Virtual Special Issue: Epigenetics 2022. (2022) (0)
Update to Our Reader, Reviewer, and Author Communities-April 2020. (2020) (0)
Update to Our Reader, Reviewer, and Author Communities-April 2020. (2020) (0)
Reaction guide, incorporating collective volumes 1-7 and annual volumes 65-68 (1991) (0)
Update to Our Reader, Reviewer, and Author Communities-April 2020. (2020) (0)
Pharmacokinetics of beta-D-2,3-didehydro-2,3-dideoxy-5-fluorocytidine in rhesus monkeys (1998) (0)
Author response: An NMDAR positive and negative allosteric modulator series share a binding site and are interconverted by methyl groups (2018) (0)
Intestinal and Prostate Cancer Models for In vivo Activity against Cancer Cell Lines and Enigmol : A Novel Sphingolipid Analogue with Anticancer (2011) (0)
Confronting Racism in Chemistry Journals. (2020) (0)
J Pharmacol Exp Ther-2014-DiRaddo-373-82 (2015) (0)
Giving Credit Where Credit Is Due: Properly Citing Relevant Prior Art. (2021) (0)
Editorial Confronting Racism in Chemistry Journals (2020) (0)
Update to Our Reader, Reviewer, and Author Communities-April 2020. (2020) (0)
Confronting Racism in Chemistry Journals. (2020) (0)
Stereocontrolled Glycosylations via Addition of Sulfur Electrophiles to Glycals. (1993) (0)
Organoselenium Chemistry I. Functional Group Transformations (1989) (0)
Update to Our Reader, Reviewer, and Author Communities-April 2020. (2020) (0)
Confronting Racism in Chemistry Journals. (2020) (0)
Pharmacokinetics of the Antiviral Agent bD-2 9 , 3 9-Didehydro-2 9 , 3 9-Dideoxy-5-Fluorocytidine in Rhesus Monkeys (1999) (0)
Confronting Racism in Chemistry Journals. (2020) (0)
Confronting Racism in Chemistry Journals. (2020) (0)
Confronting Racism in Chemistry Journals. (2020) (0)
Molecular Aggregation and Its Applicability to Synthesis. The Diels-Alder Reaction. (1989) (0)
Effects of Substitution on Intramolecular Alkoxypalladation Carbonylation Reactions. (1990) (0)
Confronting Racism in Chemistry Journals. (2020) (0)
Confronting Racism in Chemistry Journals. (2020) (0)
Process for the preparation of therapeutically useful beta-2-hydroxymethyl-5- (5-fluorocytosin-1-yl) -1,3-oxathiolane enantiomers (1993) (0)
Pyridinium Dichromate-Induced 1,3-Oxidative Rearrangements of Enynols. (1987) (0)
Long-chain (sphingoid) bases cause growth changes and cytotoxicity in Chinese hamster ovary cells (1987) (0)
Recent Reviews. 39 (1996) (0)
The method of the nucleoside 2 ', 3'-dideoxy-3' -tiapyrimidiini beta-isomer valmistamiseski (1992) (0)
Development of novel small molecule inhibitors targeting CXCR4 against cancer metastasis (2006) (0)
Ligand Assisted Nucleophilic Additions. Control of Site and Face Attack of Nucleophiles on 4‐Oxidoenones. (1988) (0)
Update to Our Reader, Reviewer, and Author Communities-April 2020. (2020) (0)
Photoelectron Spectra of Alkyl Aryl Selenides. Electronic and Steric F actors in the Observation of Rotamers. (1982) (0)
Synthesis of Enantiomerically Pure D‐FDOC, an anti‐HIV Agent. (2005) (0)
Salts of amides of (-) cis 5-fluoro-2'-3'-thiacytidine dedoxi useful for the treatment of hepatitis b. (1992) (0)
Selenium in Organic Syntheses (1986) (0)
Confronting Racism in Chemistry Journals. (2020) (0)
Update to Our Reader, Reviewer, and Author Communities-April 2020. (2020) (0)
Coal liquefaction in a fluorocarbon medium. Final report, August 1982-November 1985. [1,2,3,4-tetrahydroquinoline] (1985) (0)
Diastereoselective Addition of Chlorotitanium Enolates of N-Acyl Thiazolidinethione to Activated Imines — A Novel Synthesis of β-Lactams. (2007) (0)
236 GROWTH INHIBITORY EFFECTS OF ENIGMOL, (2-AMINO-3,5-DIHYDROXYOCTADECANE[2S,3S,5S]), ON ANDROGEN-DEPENDENT AND ANDROGEN-INDEPENDENT PROSTATE CANCER (2010) (0)
Confronting Racism in Chemistry Journals. (2020) (0)
Empirical Derivation of Molecular Mechanics Parameter Sets: Application to β-Lactams (2010) (0)
Recent Reviews. 47. (1998) (0)
Therapeutic Discovery Enigmol : A Novel Sphingolipid Analogue with Anticancer Activity against Cancer Cell Lines and In vivo Models for Intestinal and Prostate Cancer (2011) (0)
Virtual Special Issue: Epigenetics 2022. (2022) (0)
Using 5-fluoro-2'-deoxy-3'-thiacytidine for the treatment of hepatitis B (1992) (0)
A Synthesis of the Abietane Diterpenoid Quinone (.+-.)-Royleanone via Maleoylcobalt Technology. (1991) (0)
Confronting Racism in Chemistry Journals. (2020) (0)
Design and Evaluation of Nonpeptide Fibrinogen y-Chain Based GPIIbDIIa Antagonists (2001) (0)
Update to Our Reader, Reviewer, and Author Communities-April 2020. (2020) (0)
Confronting Racism in Chemistry Journals. (2020) (0)
Channel Open Probability Controls Allosteric Modulation of Potency and Efficacy (2017) (0)
Update to Our Reader, Reviewer, and Author Communities—April 2020 (2020) (0)
Salts and amides of the (-) cis-5-fluoro-2'-deoxy-thiacytidine which are suitable for the treatment of hepatitis B (1992) (0)
Correction to Reduction Sensitive Lipid Conjugates of Tenofovir: Synthesis, Stability, and Antiviral Activity. (2017) (0)
Update to Our Reader, Reviewer, and Author Communities-April 2020. (2020) (0)
A Uniquely Accessible Route to the Diastereoselective Synthesis of Azetine Derivatives. (2004) (0)
Virtual Special Issue: Epigenetics 2022. (2022) (0)

This paper list is powered by the following services:

Other Resources About Dennis C. Liotta

en.wikipedia.org

What Schools Are Affiliated With Dennis C. Liotta?

Dennis C. Liotta is affiliated with the following schools:

Image Attributions

Image Source for Dennis C. Liotta