Derek C. Angus
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American-based, British medical scientist
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Why Is Derek C. Angus Influential?
(Suggest an Edit or Addition)According to Wikipedia, Derek Calder Angus is an American-based, British medical scientist, whose work focuses on clinical, epidemiologic and translational studies of sepsis, pneumonia, multisystem organ failure and the organization and delivery of critical care services.
Derek C. Angus's Published Works
Published Works
- The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). (2016) (13437)
- Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care (2001) (8181)
- Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock 2012 (2013) (5832)
- Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock, 2012 (2013) (5425)
- 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference (2003) (4955)
- 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference (2003) (4227)
- Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008 (2007) (4099)
- Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008 (2008) (3717)
- Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016 (2017) (3647)
- Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2016 (2017) (2976)
- Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). (2016) (2599)
- Assessment of Global Incidence and Mortality of Hospital-treated Sepsis. Current Estimates and Limitations. (2016) (2109)
- A randomized trial of protocol-based care for early septic shock. (2014) (2024)
- Global, regional, and national sepsis incidence and mortality, 1990–2017: analysis for the Global Burden of Disease Study (2020) (1854)
- Severe sepsis and septic shock. (2013) (1789)
- Association Between Administration of Systemic Corticosteroids and Mortality Among Critically Ill Patients With COVID-19: A Meta-analysis. (2020) (1694)
- Developing a New Definition and Assessing New Clinical Criteria for Septic Shock: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). (2016) (1545)
- RIFLE criteria for acute kidney injury are associated with hospital mortality in critically ill patients: a cohort analysis (2006) (1448)
- Physician staffing patterns and clinical outcomes in critically ill patients: a systematic review. (2002) (1439)
- The Surviving Sepsis Campaign: results of an international guideline-based performance improvement program targeting severe sepsis (2010) (1419)
- Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19 (2021) (1105)
- Use of intensive care at the end of life in the United States: An epidemiologic study* (2004) (1104)
- Epidemiology of severe sepsis (2013) (1093)
- Incidence and Trends of Sepsis in US Hospitals Using Clinical vs Claims Data, 2009-2014 (2017) (1028)
- Caring for the critically ill patient. Current and projected workforce requirements for care of the critically ill and patients with pulmonary disease: can we meet the requirements of an aging population? (2000) (941)
- A minimal common outcome measure set for COVID-19 clinical research (2020) (939)
- Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021 (2021) (923)
- Epidemiology of sepsis: An update (2001) (853)
- The epidemiology of severe sepsis in children in the United States. (2003) (834)
- Sepsis: a roadmap for future research. (2015) (775)
- Understanding the inflammatory cytokine response in pneumonia and sepsis: results of the Genetic and Inflammatory Markers of Sepsis (GenIMS) Study. (2007) (710)
- Hospital deaths in patients with sepsis from 2 independent cohorts. (2014) (691)
- Effect of eritoran, an antagonist of MD2-TLR4, on mortality in patients with severe sepsis: the ACCESS randomized trial. (2013) (656)
- Effect of Hydrocortisone on Mortality and Organ Support in Patients With Severe COVID-19: The REMAP-CAP COVID-19 Corticosteroid Domain Randomized Clinical Trial. (2020) (583)
- Derivation, Validation, and Potential Treatment Implications of Novel Clinical Phenotypes for Sepsis. (2019) (572)
- Variation in critical care services across North America and Western Europe* (2008) (566)
- Hospitalized community-acquired pneumonia in the elderly: age- and sex-related patterns of care and outcome in the United States. (2002) (561)
- Severe community-acquired pneumonia: use of intensive care services and evaluation of American and British Thoracic Society Diagnostic criteria. (2002) (528)
- Therapeutic Anticoagulation with Heparin in Critically Ill Patients with Covid-19 (2021) (508)
- Surviving Intensive Care: a report from the 2002 Brussels Roundtable (2003) (501)
- Therapeutic Anticoagulation with Heparin in Noncritically Ill Patients with Covid-19 (2021) (485)
- Enhancing Recovery From Sepsis: A Review (2018) (484)
- The effect of multidisciplinary care teams on intensive care unit mortality. (2010) (444)
- Critical care delivery in the United States: Distribution of services and compliance with Leapfrog recommendations* (2006) (429)
- The epidemiology of mechanical ventilation use in the United States* (2010) (429)
- The Surviving Sepsis Campaign: Results of an international guideline-based performance improvement program targeting severe sepsis* (2010) (427)
- National estimates of severe sepsis in United States emergency departments (2007) (427)
- Trends in the Epidemiology of Pediatric Severe Sepsis* (2013) (423)
- Association between hospitalization for pneumonia and subsequent risk of cardiovascular disease. (2015) (416)
- A randomized, double-blind, placebo-controlled trial of TAK-242 for the treatment of severe sepsis* (2010) (384)
- Inflammatory markers at hospital discharge predict subsequent mortality after pneumonia and sepsis. (2008) (379)
- Survival after liver transplantation in the United States: A disease‐specific analysis of the UNOS database (2004) (364)
- Intensive care unit quality improvement: A “how-to” guide for the interdisciplinary team* (2006) (363)
- Acute kidney injury in non-severe pneumonia is associated with an increased immune response and lower survival. (2010) (343)
- Renal failure in the ICU: comparison of the impact of acute renal failure and end-stage renal disease on ICU outcomes. (2002) (340)
- Three-year outcomes for Medicare beneficiaries who survive intensive care. (2010) (339)
- Early, Goal‐Directed Therapy for Septic Shock — A Patient‐Level Meta‐Analysis (2017) (337)
- Quality-adjusted survival in the first year after the acute respiratory distress syndrome. (2001) (329)
- Caring for the Critically Ill Patient (2007) (324)
- A systematic review and meta-analysis of early goal-directed therapy for septic shock: the ARISE, ProCESS and ProMISe Investigators (2015) (324)
- Early Neuromuscular Blockade in the Acute Respiratory Distress Syndrome. (2019) (320)
- Protocolized sedation vs usual care in pediatric patients mechanically ventilated for acute respiratory failure: a randomized clinical trial. (2015) (319)
- Posttraumatic Stress and Complicated Grief in Family Members of Patients in the Intensive Care Unit (2008) (301)
- Effects of drotrecogin alfa (activated) on organ dysfunction in the PROWESS trial* (2003) (292)
- Effect of Hydroxychloroquine on Clinical Status at 14 Days in Hospitalized Patients With COVID-19: A Randomized Clinical Trial. (2020) (291)
- The adult respiratory distress syndrome cognitive outcomes study: long-term neuropsychological function in survivors of acute lung injury. (2012) (286)
- Drotrecogin alfa (activated) administration across clinically important subgroups of patients with severe sepsis (2003) (276)
- Severe sepsis epidemiology: sampling, selection, and society (2004) (274)
- Community-acquired pneumonia in the elderly. (2003) (273)
- The search for effective therapy for sepsis: back to the drawing board? (2011) (264)
- The Epidemiology of Chronic Critical Illness in the United States* (2015) (264)
- Nighttime intensivist staffing and mortality among critically ill patients. (2012) (263)
- Prevalence and Outcomes of Infection Among Patients in Intensive Care Units in 2017. (2020) (263)
- Infection rate and acute organ dysfunction risk as explanations for racial differences in severe sepsis. (2010) (260)
- Intensive care unit safety culture and outcomes: a US multicenter study. (2010) (257)
- A Randomized Trial of a Family‐Support Intervention in Intensive Care Units (2018) (256)
- Racial variation in the incidence, care, and outcomes of severe sepsis: analysis of population, patient, and hospital characteristics. (2008) (241)
- The critical care crisis in the United States: A report from the profession (2004) (241)
- Perceptions of safety culture vary across the intensive care units of a single institution* (2007) (239)
- Late mortality after sepsis: propensity matched cohort study (2016) (232)
- Long-term mortality and medical care charges in patients with severe sepsis (2003) (231)
- Toward Smarter Lumping and Smarter Splitting: Rethinking Strategies for Sepsis and Acute Respiratory Distress Syndrome Clinical Trial Design. (2016) (231)
- E5 murine monoclonal antiendotoxin antibody in gram-negative sepsis: a randomized controlled trial. E5 Study Investigators. (2000) (231)
- COST-EFFECTIVENESS OF DROTRECOGIN ALFA (ACTIVATED) IN THE TREATMENT OF SEVERE SEPSIS (2002) (227)
- End-of-life care for the critically ill: A national intensive care unit survey* (2006) (226)
- Comparison of medical admissions to intensive care units in the United States and United Kingdom. (2011) (216)
- Severe sepsis in pre-hospital emergency care: analysis of incidence, care, and outcome. (2012) (208)
- Circulating high-mobility group box 1 (HMGB1) concentrations are elevated in both uncomplicated pneumonia and pneumonia with severe sepsis* (2007) (206)
- Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021. (2021) (204)
- The association of sepsis syndrome and organ dysfunction with mortality in emergency department patients with suspected infection. (2006) (199)
- Association Between the New York Sepsis Care Mandate and In-Hospital Mortality for Pediatric Sepsis (2018) (194)
- The challenge of admitting the very elderly to intensive care (2011) (191)
- Impact of acute renal failure on mortality in end-stage liver disease with or without transplantation. (1998) (190)
- The first international consensus conference on continuous renal replacement therapy. (2002) (189)
- The epidemiology of sepsis in Brazilian intensive care units (the Sepsis PREvalence Assessment Database, SPREAD): an observational study. (2017) (188)
- Implications of Heterogeneity of Treatment Effect for Reporting and Analysis of Randomized Trials in Critical Care. (2015) (188)
- Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19 from an international collaborative meta-analysis of randomized trials (2020) (184)
- Epidemiology of neonatal respiratory failure in the United States: projections from California and New York. (2001) (183)
- Long-Term Quality of Life Among Survivors of Severe Sepsis: Analyses of Two International Trials* (2016) (182)
- The REMAP-CAP (Randomized Embedded Multifactorial Adaptive Platform for Community-acquired Pneumonia) Study. Rationale and Design (2020) (181)
- Temporal changes in management and outcome of septic shock in patients with malignancies in the intensive care unit* (2008) (180)
- Outcomes research in critical care: results of the American Thoracic Society Critical Care Assembly Workshop on Outcomes Research. The Members of the Outcomes Research Workshop. (1999) (175)
- Epidemiology of severe sepsis around the world. (2006) (175)
- The global burden of sepsis: barriers and potential solutions (2018) (171)
- The effect of drotrecogin alfa (activated) on long-term survival after severe sepsis * (2004) (170)
- The Next Generation of Sepsis Clinical Trial Designs: What Is Next After the Demise of Recombinant Human Activated Protein C?* (2014) (168)
- Predicting hospital mortality for patients in the intensive care unit: A comparison of artificial neural networks with logistic regression models (2001) (164)
- Disability among elderly survivors of mechanical ventilation. (2011) (163)
- Severe sepsis in community-acquired pneumonia: when does it happen, and do systemic inflammatory response syndrome criteria help predict course? (2006) (157)
- The Effects of Alternative Resuscitation Strategies on Acute Kidney Injury in Patients with Septic Shock. (2016) (156)
- Pneumonia: still the old man's friend? (2003) (155)
- Informal caregiver burden among survivors of prolonged mechanical ventilation. (2007) (155)
- Use of intensive care services during terminal hospitalizations in England and the United States. (2009) (153)
- Bidirectional relationship between cognitive function and pneumonia. (2013) (151)
- Outcome measures for clinical research in sepsis: A report of the 2nd Cambridge Colloquium of the International Sepsis Forum (2005) (147)
- A guide to immunotherapy for COVID-19 (2022) (146)
- Default options in advance directives influence how patients set goals for end-of-life care. (2013) (146)
- Fusing Randomized Trials With Big Data: The Key to Self-learning Health Care Systems? (2015) (144)
- The microcirculation image quality score: development and preliminary evaluation of a proposed approach to grading quality of image acquisition for bedside videomicroscopy. (2013) (143)
- Haloperidol use is associated with lower hospital mortality in mechanically ventilated patients* (2005) (143)
- Growth of intensive care unit resource use and its estimated cost in Medicare* (2008) (143)
- Association of the Quick Sequential (Sepsis-Related) Organ Failure Assessment (qSOFA) Score With Excess Hospital Mortality in Adults With Suspected Infection in Low- and Middle-Income Countries (2018) (143)
- Critical care bed growth in the United States. A comparison of regional and national trends. (2015) (142)
- Midregional proadrenomedullin as a prognostic tool in community-acquired pneumonia. (2009) (139)
- Optimizing the Trade-off Between Learning and Doing in a Pandemic. (2020) (138)
- Variability of Intensive Care Admission Decisions for the Very Elderly (2012) (135)
- Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008 (2008) (135)
- Understanding costs and cost-effectiveness in critical care: report from the second American Thoracic Society workshop on outcomes research. (2002) (135)
- Current challenges in the management of sepsis in ICUs in resource-poor settings and suggestions for the future (2017) (134)
- Adaptive platform trials: definition, design, conduct and reporting considerations (2019) (132)
- The ICM research agenda on intensive care unit-acquired weakness (2017) (131)
- Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19 - Preliminary report (2021) (131)
- Effect of a Quality Improvement Intervention With Daily Round Checklists, Goal Setting, and Clinician Prompting on Mortality of Critically Ill Patients: A Randomized Clinical Trial. (2016) (130)
- Plasma neutrophil gelatinase-associated lipocalin predicts recovery from acute kidney injury following community-acquired pneumonia (2011) (129)
- The lingering consequences of sepsis: a hidden public health disaster? (2010) (129)
- A Clinically Based Discrete-Event Simulation of End-Stage Liver Disease and the Organ Allocation Process (2005) (128)
- A Framework for the Development and Interpretation of Different Sepsis Definitions and Clinical Criteria (2016) (124)
- A comparison of critical care research funding and the financial burden of critical illness in the United States* (2012) (124)
- Effect of Convalescent Plasma on Organ Support-Free Days in Critically Ill Patients With COVID-19: A Randomized Clinical Trial. (2021) (123)
- Risk of cardiovascular events in survivors of severe sepsis. (2014) (123)
- Prevalence and Significance of Coagulation Abnormalities in Community-Acquired Pneumonia (2009) (122)
- Potential value of regionalized intensive care for mechanically ventilated medical patients. (2008) (122)
- Passive decision-making preference is associated with anxiety and depression in relatives of patients in the intensive care unit. (2009) (121)
- Immune Checkpoint Inhibition in Sepsis: A Phase 1b Randomized, Placebo-Controlled, Single Ascending Dose Study of Antiprogrammed Cell Death-Ligand 1 Antibody (BMS-936559)* (2019) (120)
- Mortality among patients admitted to strained intensive care units. (2013) (119)
- Racial variation in end-of-life intensive care use: a race or hospital effect? (2006) (116)
- Organizational characteristics, outcomes, and resource use in 78 Brazilian intensive care units: the ORCHESTRA study (2015) (113)
- Reorganizing adult critical care delivery: the role of regionalization, telemedicine, and community outreach. (2010) (113)
- Guidelines for critical care medicine training and continuing medical education (2004) (113)
- Multinational, observational study of procalcitonin in ICU patients with pneumonia requiring mechanical ventilation: a multicenter observational study (2011) (111)
- Sepsis: Something old, something new, and a systems view. (2012) (111)
- Is Survival Better at Hospitals With Higher “End-of-Life” Treatment Intensity? (2010) (108)
- Recovery after critical illness: putting the puzzle together—a consensus of 29 (2017) (108)
- Prioritizing the organization and management of intensive care services in the United States: The PrOMIS Conference* (2007) (107)
- Healthcare costs and long-term outcomes after acute respiratory distress syndrome: A phase III trial of inhaled nitric oxide* (2006) (106)
- Assessing the feasibility of the American College of Surgeons' benchmarks for the triage of trauma patients. (2011) (105)
- Improved Early Detection of Sepsis in the ED With a Novel Monocyte Distribution Width Biomarker (2017) (104)
- 36th International Symposium on Intensive Care and Emergency Medicine (2016) (103)
- Delays From First Medical Contact to Antibiotic Administration for Sepsis* (2017) (102)
- Psychiatric diagnoses and psychoactive medication use among nonsurgical critically ill patients receiving mechanical ventilation. (2014) (102)
- Patients are dying of acute renal failure. (2002) (101)
- A PROSPECTIVE, OBSERVATIONAL STUDY OF SOLUBLE FLT-1 AND VASCULAR ENDOTHELIAL GROWTH FACTOR IN SEPSIS (2008) (101)
- Development and Validation of Hospital “End-of-Life” Treatment Intensity Measures (2009) (100)
- The Volume-Outcome Relationship in Critical Care: A Systematic Review and Meta-analysis. (2015) (99)
- The influence of pre-existing diabetes mellitus on the host immune response and outcome of pneumonia: analysis of two multicentre cohort studies (2010) (99)
- The research agenda in ICU telemedicine: a statement from the Critical Care Societies Collaborative. (2011) (98)
- Elevated Hemostasis Markers after Pneumonia Increases One-Year Risk of All-Cause and Cardiovascular Deaths (2011) (97)
- Immune checkpoint inhibition in sepsis: a Phase 1b randomized study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of nivolumab (2019) (96)
- The ethical conduct of clinical research involving critically ill patients in the United States and Canada: principles and recommendations. (2004) (95)
- How the COVID-19 pandemic will change the future of critical care (2021) (95)
- Intravenous fluid resuscitation is associated with septic endothelial glycocalyx degradation (2019) (94)
- Understanding the potential role of statins in pneumonia and sepsis* (2011) (94)
- Calcium/Calmodulin-Dependent Protein Kinase (CaMK) IV Mediates Nucleocytoplasmic Shuttling and Release of HMGB1 during Lipopolysaccharide Stimulation of Macrophages1 (2008) (93)
- The efficacy and safety of prokinetic agents in critically ill patients receiving enteral nutrition: a systematic review and meta-analysis of randomized trials (2016) (92)
- Hospital mortality and resource use in subgroups of the Recombinant Human Activated Protein C Worldwide Evaluation in Severe Sepsis (PROWESS) trial * (2004) (92)
- Drotrecogin alfa (activated) treatment of older patients with severe sepsis. (2003) (91)
- Methods to adjust for bias and confounding in critical care health services research involving observational data. (2006) (91)
- Cardiopulmonary resuscitation: what cost to cheat death? (1996) (90)
- Risk prediction with procalcitonin and clinical rules in community-acquired pneumonia. (2008) (89)
- Efficacy of Remdesivir in COVID-19. (2020) (89)
- Potentially Inadvertent Immunomodulation: Norepinephrine Use in Sepsis. (2016) (88)
- Precision medicine for all? Challenges and opportunities for a precision medicine approach to critical illness (2017) (88)
- Therapeutic Anticoagulation in Critically Ill Patients with Covid-19-Preliminary Report (2021) (88)
- Long-term outcomes from sepsis (2007) (86)
- Intensive insulin therapy in critical illness. (2005) (85)
- Protocol-based care for early septic shock. (2014) (85)
- Improving care of the critically ill: institutional and health-care system approaches (2004) (85)
- Open source clinical science for emerging infections (2013) (80)
- Effects of Organizational Characteristics on Outcomes and Resource Use in Patients With Cancer Admitted to Intensive Care Units. (2016) (80)
- Monocyte Distribution Width: A Novel Indicator of Sepsis-2 and Sepsis-3 in High-Risk Emergency Department Patients* (2019) (79)
- The PIRO concept: P is for predisposition (2003) (79)
- Anticoagulant interventions in hospitalized patients with COVID‐19: A scoping review of randomized controlled trials and call for international collaboration (2020) (78)
- Point-of-care sensors for the management of sepsis (2018) (78)
- Metabolomics in pneumonia and sepsis: an analysis of the GenIMS cohort study (2013) (77)
- The prevalence of anemia and its association with 90-day mortality in hospitalized community-acquired pneumonia (2010) (77)
- Association Between State-Mandated Protocolized Sepsis Care and In-hospital Mortality Among Adults With Sepsis. (2019) (76)
- ICU Telemedicine and Critical Care Mortality: A National Effectiveness Study (2016) (76)
- Implementation of early goal-directed therapy for severe sepsis and septic shock: A decision analysis (2007) (76)
- Sociodemographic Differences in Early Access to Liver Transplantation Services (2009) (76)
- An Analysis of Prehospital Mortality in an Earthquake (1994) (75)
- International comparisons of critical care outcome and resource consumption. (1997) (75)
- Long-term Host Immune Response Trajectories Among Hospitalized Patients With Sepsis (2019) (74)
- Serum Biomarkers of Brain Injury to Classify Outcome After Pediatric Cardiac Arrest* (2014) (74)
- Prehospital intravenous access and fluid resuscitation in severe sepsis: an observational cohort study (2014) (73)
- The Effects of Trauma Center Care, Admission Volume, and Surgical Volume on Paralysis After Traumatic Spinal Cord Injury (2009) (73)
- Executive Summary: Surviving Sepsis Campaign: International Guidelines for the Management of Sepsis and Septic Shock 2021 (2021) (72)
- Trends in Admissions for Pediatric Status Asthmaticus in New Jersey Over a 15-Year Period (2010) (71)
- Differences in immune response may explain lower survival among older men with pneumonia* (2009) (71)
- Effects of intra-abdominal sepsis on atherosclerosis in mice (2014) (71)
- Sepsis Surveillance Using Adult Sepsis Events Simplified eSOFA Criteria Versus Sepsis-3 Sequential Organ Failure Assessment Criteria* (2019) (70)
- Parenteral calcium for intensive care unit patients. (2008) (70)
- Variability in management of early severe sepsis (2010) (69)
- Endothelial Permeability and Hemostasis in Septic Shock: Results From the ProCESS Trial (2017) (69)
- Application of a Framework to Assess the Usefulness of Alternative Sepsis Criteria (2016) (69)
- Economics of end-of-life care in the intensive care unit (2001) (68)
- Using simulation to isolate physician variation in intensive care unit admission decision making for critically ill elders with end-stage cancer: A pilot feasibility study* (2008) (67)
- Calcium Supplementation During Sepsis Exacerbates Organ Failure and Mortality via Calcium/Calmodulin-Dependent Protein Kinase Kinase Signaling (2013) (67)
- Bench-to-bedside review: Avoiding pitfalls in critical care meta-analysis – funnel plots, risk estimates, types of heterogeneity, baseline risk and the ecologic fallacy (2008) (65)
- Declining case fatality rates for severe sepsis: good data bring good news with ambiguous implications. (2014) (65)
- Development and Validation of a Mortality Prediction Model for Patients Receiving 14 Days of Mechanical Ventilation (2015) (65)
- Understanding and Enhancing Sepsis Survivorship: Priorities for Research and Practice. (2019) (65)
- Hospitalizations of Children With Neurologic Disorders in the United States (2013) (64)
- Grappling with intensive care unit quality--does the readmission rate tell us anything? (1998) (62)
- Early Neuromuscular Blockade in the Acute Respiratory Distress Syndrome. Reply. (2019) (61)
- Preparing for the Sickest Patients With 2009 Influenza A(H1N1). (2009) (61)
- Cost-effectiveness of drotrecogin alfa (activated) for the treatment of severe sepsis in Germany. (2003) (60)
- Acute lung injury--affecting many lives. (2005) (60)
- Hospital costs in patients receiving prolonged mechanical ventilation: does age have an impact? (2003) (59)
- Barriers to implementing the Leapfrog Group recommendations for intensivist physician staffing: a survey of intensive care unit directors. (2007) (59)
- Improving clinical trials in the critically ill (2010) (58)
- Access to urban acute care services in high- vs. middle-income countries: an analysis of seven cities (2013) (58)
- Critical care: the impact of organization and management on outcomes (2010) (58)
- The intensive care medicine research agenda on septic shock (2017) (57)
- International Survey of Critically Ill Children With Acute Neurologic Insults: The Prevalence of Acute Critical Neurological Disease in Children A Global Epidemiological Assessment Study* (2017) (57)
- Incorporating Biological Natural History in Simulation Models: Empirical Estimates of the Progression of End-Stage Liver Disease (2005) (57)
- Neuromuscular blockade in patients with ARDS: a rapid practice guideline (2020) (57)
- Infection Hospitalization Increases Risk of Dementia in the Elderly* (2014) (56)
- Bench-to-bedside review: The evaluation of complex interventions in critical care (2008) (56)
- Do hospitals provide lower quality of care to black patients for pneumonia?* (2010) (56)
- Use of Intensive Care Services for Medicare Beneficiaries Undergoing Major Surgical Procedures (2016) (56)
- Efficacy and safety of a phospholipid emulsion (GR270773) in Gram-negative severe sepsis: Results of a phase II multicenter, randomized, placebo-controlled, dose-finding clinical trial (2009) (56)
- AGE-SPECIFIC INCIDENCE AND OUTCOME OF SEPSIS IN THE US (1999) (56)
- How does lack of insurance affect use of intensive care? A population-based study* (2006) (55)
- Sepsis: frontiers in supportive care, organisation and research (2017) (54)
- Pharmacoeconomic Implications of New Therapies in Sepsis (2012) (54)
- Toward Better ICU Use at the End of Life. (2016) (54)
- Short‐term and long‐term outcome prediction with the Acute Physiology and Chronic Health Evaluation II system after orthotopic liver transplantation (2000) (54)
- InFACT: a global critical care research response to H1N1 (2010) (53)
- Are Intensivists Safe? (2008) (53)
- Effect of Antiplatelet Therapy on Survival and Organ Support-Free Days in Critically Ill Patients With COVID-19: A Randomized Clinical Trial. (2022) (52)
- Redefining critical illness (2022) (52)
- Prospective meta-analysis using individual patient data in intensive care medicine (2009) (52)
- Toward an integrated research agenda for critical illness in aging. (2010) (51)
- Plasma metabolomics for the diagnosis and prognosis of H1N1 influenza pneumonia (2017) (51)
- Long‐Term Outcomes after Protocolized Sedation versus Usual Care in Ventilated Pediatric Patients (2018) (50)
- Time for Clinicians to Embrace Their Inner Bayesian?: Reanalysis of Results of a Clinical Trial of Extracorporeal Membrane Oxygenation. (2018) (49)
- Value and role of intensive care unit outcome prediction models in end-of-life decision making. (2004) (49)
- Physician attitudes toward regionalization of adult critical care: A national survey* (2009) (49)
- Determinants of Intensive Care Unit Telemedicine Effectiveness. An Ethnographic Study (2019) (49)
- Efficacy of educational video game versus traditional educational apps at improving physician decision making in trauma triage: randomized controlled trial (2017) (49)
- Lopinavir-ritonavir and hydroxychloroquine for critically ill patients with COVID-19: REMAP-CAP randomized controlled trial (2021) (48)
- Epidemiology and long-term clinical and biologic risk factors for pneumonia in community-dwelling older Americans: analysis of three cohorts. (2013) (48)
- Design and Rationale of the Reevaluation of Systemic Early Neuromuscular Blockade Trial for Acute Respiratory Distress Syndrome (2017) (48)
- Epidemiologic Assessment of Mortality, Building Collapse Pattern, and Medical Response after the 1992 Earthquake in Turkey (1997) (47)
- Unraveling severe sepsis: why did OPTIMIST fail and what's next? (2003) (47)
- Learning patient-specific predictive models from clinical data (2010) (47)
- The effect of light on critical illness (2011) (47)
- Quality of Death: Assessing the Importance Placed on End-of-Life Treatment in the Intensive-Care Unit (2004) (47)
- Critical care medicine training and certification for emergency physicians* (2005) (46)
- Microcirculatory perfusion disturbances in septic shock: results from the ProCESS trial (2018) (46)
- Risk Factors for Functional Decline and Impaired Quality of Life after Pediatric Respiratory Failure. (2019) (46)
- Impact of Bamlanivimab Monoclonal Antibody Treatment on Hospitalization and Mortality Among Nonhospitalized Adults With Severe Acute Respiratory Syndrome Coronavirus 2 Infection (2021) (45)
- Sepsis Subclasses: A Framework for Development and Interpretation. (2021) (45)
- Cost-effectiveness of inhaled nitric oxide in the treatment of neonatal respiratory failure in the United States. (2003) (44)
- Randomized Clinical Trials of Artificial Intelligence. (2020) (44)
- Economic evaluation of new therapies in critical illness (2003) (44)
- Does acute organ dysfunction predict patient-centered outcomes? (2002) (43)
- Immunotherapy in sepsis (1992) (43)
- 4G/5G plasminogen activator inhibitor-1 polymorphisms and haplotypes are associated with pneumonia. (2007) (43)
- Drotrecogin alfa (activated) ... a sad final fizzle to a roller-coaster party (2012) (43)
- Patterns of Opioid Administration Among Opioid-Naive Inpatients and Associations With Postdischarge Opioid Use (2019) (43)
- Harmonizing international trials of early goal-directed resuscitation for severe sepsis and septic shock: methodology of ProCESS, ARISE, and ProMISe (2013) (43)
- Designing phase 3 sepsis trials: application of learned experiences from critical care trials in acute heart failure (2016) (43)
- Omega-3 supplementation in patients with sepsis: a systematic review and meta-analysis of randomized trials (2017) (42)
- The Effect of Pulmonary Artery Catheter Use on Costs and Long-Term Outcomes of Acute Lung Injury (2011) (42)
- Bench-to-bedside review: Critical illness-associated cognitive dysfunction – mechanisms, markers, and emerging therapeutics (2006) (42)
- Interplay between sepsis and chronic health. (2014) (42)
- Improving clinical trial design in acute lung injury (2003) (40)
- Quality of care and resource use among mechanically ventilated patients before and after an intervention to assist nurse-nonvocal patient communication. (2015) (40)
- Surviving Intensive Care (2003) (39)
- Long-term survival in patients with septic acute kidney injury is strongly influenced by renal recovery (2018) (39)
- Cost-Effectiveness of Fixed-Dose Combination of Isosorbide Dinitrate and Hydralazine Therapy for Blacks With Heart Failure (2005) (39)
- Impact of Nurse-Led Remote Screening and Prompting for Evidence-Based Practices in the ICU* (2014) (39)
- Translating research evidence into clinical practice: new challenges for critical care (2002) (39)
- Association Between Preoperative Metformin Exposure and Postoperative Outcomes in Adults With Type 2 Diabetes. (2020) (39)
- Caring for the critically ill patient: challenges and opportunities. (2007) (39)
- The Effects of Age on Inflammatory and Coagulation-Fibrinolysis Response in Patients Hospitalized for Pneumonia (2010) (38)
- A Proposed Lottery System to Allocate Scarce COVID-19 Medications: Promoting Fairness and Generating Knowledge. (2020) (38)
- Variation in Identifying Sepsis and Organ Dysfunction Using Administrative Versus Electronic Clinical Data and Impact on Hospital Outcome Comparisons* (2019) (38)
- Comparison of Cox and Gray’s survival models in severe sepsis* (2004) (38)
- Health policy and future planning for survivors of critical illness (2007) (38)
- Association of statin use with risk and outcome of acute kidney injury in community-acquired pneumonia. (2012) (38)
- Women in Intensive Care study: a preliminary assessment of international data on female representation in the ICU physician workforce, leadership and academic positions (2018) (38)
- Emerging Lessons From COVID-19 for the US Clinical Research Enterprise. (2021) (37)
- Immunosuppression and Secondary Infection in Sepsis: Part, Not All, of the Story. (2016) (37)
- Admitting Elderly Patients to the Intensive Care Unit-Is it the Right Decision? (2017) (37)
- Validating a Vignette-Based Instrument to Study Physician Decision Making in Trauma Triage (2014) (37)
- A randomized trial of the effect of patient race on physicians' intensive care unit and life-sustaining treatment decisions for an acutely unstable elder with end-stage cancer* (2011) (37)
- Relationship Between Alternative Resuscitation Strategies, Host Response and Injury Biomarkers, and Outcome in Septic Shock: Analysis of the Protocol-Based Care for Early Septic Shock Study (2017) (37)
- Geographic Access to High Capability Severe Acute Respiratory Failure Centers in the United States (2014) (36)
- Cost reduction and quality improvement: it takes two to tango. (2000) (35)
- Proteomics reveals age-related differences in the host immune response to sepsis. (2014) (35)
- Organizational Determinants of Hospital End-of-Life Treatment Intensity (2009) (35)
- Long-term impact of sepsis on cardiovascular health (2018) (35)
- Hospital Variation in Risk-Adjusted Pediatric Sepsis Mortality* (2018) (34)
- Use of Biotelemetry to Define Physiology-Based Deterioration Thresholds in a Murine Cecal Ligation and Puncture Model of Sepsis (2016) (34)
- ICU staffing feature phenotypes and their relationship with patients’ outcomes: an unsupervised machine learning analysis (2019) (34)
- Precision Medicine for COVID-19: Phenotype Anarchy or Promise Realized? (2021) (34)
- Selective decontamination of the digestive tract. (1990) (33)
- Dynamic microsimulation to model multiple outcomes in cohorts of critically ill patients (2004) (33)
- Advance Care Planning Norms May Contribute to Hospital Variation in End-of-Life ICU Use (2014) (33)
- Arguing for Adaptive Clinical Trials in Sepsis (2018) (32)
- Blue light reduces organ injury from ischemia and reperfusion (2016) (31)
- Sources of non-compliance with clinical practice guidelines in trauma triage: a decision science study (2012) (31)
- Health status versus utilities of patients with end-stage liver disease (2004) (31)
- Using large-scale databases to measure outcomes in critical care. (1999) (31)
- Risk prediction: judging the judges (1997) (30)
- Therapeutic Anticoagulation in Non-Critically Ill Patients with Covid-19 (2021) (30)
- When should a mechanically ventilated patient undergo tracheostomy? (2013) (30)
- Reducing the cost of critical care: new challenges, new solutions. (2006) (30)
- Development and validation of an algorithm for identifying prolonged mechanical ventilation in administrative data (2009) (30)
- Determinants of Compliance With Transfer Guidelines for Trauma Patients: A Retrospective Analysis of CT Scans Acquired Prior to Transfer to a Level I Trauma Center (2010) (30)
- Clinical and Economic Effects of iNO in Premature Newborns With Respiratory Failure at 1 Year (2009) (30)
- Assessing the Validity of Using Serious Game Technology to Analyze Physician Decision Making (2014) (30)
- Impact of Volume Change Over Time on Trauma Mortality in the United States (2017) (29)
- Children with Chronic Disease Bear the Highest Burden of Pediatric Sepsis (2018) (29)
- Global outbreak research: harmony not hegemony (2020) (28)
- Adults with septic shock and extreme hyperferritinemia exhibit pathogenic immune variation (2018) (28)
- Pediatric Traumatic Brain Injury Is Inconsistently Regionalized in the United States (2008) (28)
- Identifying Clinical Research Priorities in Adult Pulmonary and Critical Care: NHLBI Working Group Report. (2020) (28)
- EARLY FLUID RESUSCITATION IN SEPSIS: EVIDENCE AND PERSPECTIVES (2010) (28)
- Daily chlorhexidine bathing for critically ill patients: a note of caution. (2015) (27)
- CARING FOR THE CRITICALLY ILL PATIENT Physician Staffing Patterns and Clinical Outcomes in Critically Ill Patients (2002) (27)
- Potential mechanisms and markers of critical illness-associated cognitive dysfunction (2005) (27)
- Rationale and Design of an Adaptive Phase 2b/3 Clinical Trial of Selepressin for Adults in Septic Shock. Selepressin Evaluation Programme for Sepsis-induced Shock-Adaptive Clinical Trial. (2018) (27)
- Socioeconomic factors associated with outcome after cardiac arrest in patients under the age of 65. (2015) (27)
- Corticosteroid therapy for critically ill patients with COVID-19: A structured summary of a study protocol for a prospective meta-analysis of randomized trials (2020) (27)
- Going home on the right medications: prescription errors and transitions of care. (2011) (27)
- Intensive care unit readmission during childhood after preterm birth with respiratory failure. (2014) (27)
- Relationship between staff perceptions of hospital norms and hospital-level end-of-life treatment intensity. (2007) (27)
- Post-Preparedness Medical Disaster Response in Costa Rica (1994) (26)
- Opening the Debate on the New Sepsis Definition Defining Sepsis: A Case of Bounded Rationality and Fuzzy Thinking? (2016) (26)
- International comparisons in critical care: a necessity and challenge (2007) (26)
- Oxygen Therapy for the Critically Ill. (2020) (26)
- A new conceptual framework for ICU performance appraisal and improvement. (2002) (25)
- Trauma triage in the emergency departments of nontrauma centers: An analysis of individual physician caseload on triage patterns (2013) (25)
- Measuring resource use in the ICU with computerized therapeutic intervention scoring system-based data. (1998) (25)
- Trial of shift scheduling with standardized sign-out to improve continuity of care in intensive care units* (2012) (25)
- Perceived barriers to the regionalization of adult critical care in the United States: a qualitative preliminary study (2008) (24)
- The acute respiratory distress syndrome: what's in a name? (2012) (24)
- Serial Measurement of Cell-cycle Arrest Biomarkers [TIMP-2]•[IGFBP7] and Risk for Progression to Death, Dialysis or Severe Acute Kidney Injury in Patients with Septic Shock. (2020) (24)
- Serial Measurement of Cell-cycle Arrest Biomarkers [TIMP-2]•[IGFBP7] and Risk for Progression to Death, Dialysis or Severe Acute Kidney Injury in Patients with Septic Shock. (2020) (24)
- Light and the outcome of the critically ill: an observational cohort study (2012) (24)
- Prompt Administration of Antibiotics and Fluids in the Treatment of Sepsis: A Murine Trial* (2018) (24)
- Accuracy of prehospital transport time estimation. (2014) (24)
- Incorporating biology into discrete event simulation models of organ allocation (2002) (23)
- Postsepsis Morbidity. (2018) (23)
- Scoring system fatigue...and the search for a way forward. (2000) (23)
- PAC-Man: Game over for the pulmonary artery catheter? (2006) (23)
- Thought outside the box: Intensive care unit freakonomics and decision making in the intensive care unit (2010) (23)
- Testing protocols in the intensive care unit: complex trials of complex interventions for complex patients. (2008) (23)
- Randomised clinical trials in critical care: past, present and future (2021) (22)
- Making a pragmatic choice for fluid resuscitation in critically ill patients. (2013) (22)
- Critically ill patients with influenza A(H1N1)pdm09 virus infection in 2014. (2014) (22)
- Intensive care unit renal support therapy volume is not associated with patient outcome* (2011) (22)
- Treatment Patterns and Clinical Outcomes After the Introduction of the Medicare Sepsis Performance Measure (SEP-1) (2021) (22)
- Toward Universal Deployable Guidelines for the Care of Patients With COVID-19. (2020) (22)
- Wider lessons of the pulmonary artery catheter trial (2001) (22)
- Management of sepsis: a 47-year-old woman with an indwelling intravenous catheter and sepsis. (2011) (22)
- Serious games may improve physician heuristics in trauma triage (2018) (21)
- A road map from single-cell transcriptome to patient classification for the immune response to trauma (2020) (21)
- 24 vs. 72 hours of hypothermia for pediatric cardiac arrest: A pilot, randomized controlled trial. (2018) (21)
- The influence of clinical study design on cost-effectiveness projections for the treatment of gram-negative sepsis with human anti-endotoxin antibody. (1995) (21)
- Reassessing the value of short-term mortality in sepsis: Comparing conventional approaches to modeling (2003) (21)
- Prospective evaluation of COVID-19 vaccine responses across a broad spectrum of immunocompromising conditions: the COVICS study. (2022) (21)
- Effective Care Practices in Patients Receiving Prolonged Mechanical Ventilation: An Ethnographic Study. (2020) (20)
- Results of the American Thoracic Society Critical Care Assembly Workshop on Outcomes Research (1999) (20)
- Forging a critical alliance: Addressing the research needs of the United States critical illness and injury community* (2009) (19)
- Association between ICU physician staffing and outcomes: A systematic review (1999) (19)
- Evaluation of Repeated Quick Sepsis-Related Organ Failure Assessment Measurements Among Patients With Suspected Infection* (2018) (19)
- The Effect of Race, Sex, and Insurance Status on Time-to-Listing Decisions for Liver Transplantation (2010) (19)
- Critical Care Organizations: Building and Integrating Academic Programs (2017) (19)
- Improving risk classification of critical illness with biomarkers: a simulation study. (2013) (18)
- Is High-Dose Vitamin C Beneficial for Patients With Sepsis? (2019) (18)
- Implementation of the Randomized Embedded Multifactorial Adaptive Platform for COVID-19 (REMAP-COVID) trial in a US health system—lessons learned and recommendations (2021) (18)
- The UPMC OPTIMISE-C19 (OPtimizing Treatment and Impact of Monoclonal antIbodieS through Evaluation for COVID-19) trial: a structured summary of a study protocol for an open-label, pragmatic, comparative effectiveness platform trial with response-adaptive randomization (2021) (18)
- Modeling hospital discharge policies for patients with pneumonia-related sepsis (2008) (18)
- No child left behind: Enrolling children and adults simultaneously in critical care randomized trials* (2009) (18)
- External validation of a prehospital risk score for critical illness (2016) (17)
- The effects of drotrecogin alfa (activated) on long-term survival after severe sepsis. (Treatment of severe sepsis with drotrecogin alfa (activated): report of long-term follow-up, open label use and cumulative safety update data: Tuesday, November 5, 2002 1:45pm-2:45pm) (2002) (17)
- Protocolized Care for Early Septic Shock (ProCESS) statistical analysis plan. (2013) (17)
- Testing a videogame intervention to recalibrate physician heuristics in trauma triage: study protocol for a randomized controlled trial (2016) (17)
- Bench-to-bedside review: Genetics and proteomics: deciphering gene association studies in critical illness (2006) (17)
- Effect of Default Options in Advance Directives on Hospital-Free Days and Care Choices Among Seriously Ill Patients: A Randomized Clinical Trial. (2020) (17)
- A Research Agenda for Precision Medicine in Sepsis and Acute Respiratory Distress Syndrome: An Official American Thoracic Society Research Statement (2021) (17)
- Predicting late anemia in critical illness (2006) (16)
- Recommendations for Life-Supporting First-Aid Training of the Lay Public for Disaster Preparedness (1993) (16)
- Variation in mortality rates after admission to long‐term acute care hospitals for ventilator weaning (2018) (16)
- A review of therapeutic attempts to recruit the microcirculation in patients with sepsis. (2014) (16)
- Blue Light Enhances Bacterial Clearance and Reduces Organ Injury During Sepsis* (2018) (16)
- Traumatic Brain Injury and Infectious Encephalopathy in Children From Four Resource-Limited Settings in Africa* (2018) (16)
- Acute renal failure in recipients of organ transplantation and nontransplantation patients: comparison of characteristics and mortality. (1997) (15)
- Guidelines for Rescue Training of the Lay Public (1993) (15)
- Use of dynamic microsimulation to predict disease progression in patients with pneumonia-related sepsis (2007) (15)
- Long-term (180-Day) Outcomes in Critically Ill Patients With COVID-19 in the REMAP-CAP Randomized Clinical Trial. (2022) (15)
- The clinical research enterprise in critical care: What’s right, what’s wrong, and what’s ahead? (2009) (15)
- Severe Sepsis In Prehospital Emergency Care: Analysis Of Incidence, Care, And Outcome (2012) (15)
- Clinical evaluation of the new RIFLE criteria for acute renal failure (2004) (15)
- Noninvasive positive pressure ventilation in acute respiratory failure: report of an International Consensus Conference in intensive care medicine, Paris, France, 13-14 April 2000* (2001) (14)
- Living with uncertainty in the intensive care unit: should patients with sepsis be treated with steroids? (2009) (14)
- The International Community-Acquired Pneumonia (CAP) Collaboration Cohort (ICCC) study: rationale, design and description of study cohorts and patients (2012) (14)
- Referral Regions for Time‐Sensitive Acute Care Conditions in the United States (2018) (14)
- Genetic variation and risk of sepsis. (2003) (14)
- Metallothionein-induced zinc partitioning exacerbates hyperoxic acute lung injury. (2013) (14)
- Enabling a learning healthcare system with automated computer protocols that produce replicable and personalized clinician actions (2021) (13)
- Not Thinking Clearly? Play a Game, Seriously! (2016) (13)
- Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19. Reply. (2021) (13)
- Severity scoring systems in the modern intensive care unit. (1998) (13)
- Murine sepsis phenotypes and differential treatment effects in a randomized trial of prompt antibiotics and fluids (2019) (13)
- Choosing wisely(®) in critical care: maximizing value in the intensive care unit. (2014) (12)
- Designing clinical trials in acute lung injury/acute respiratory distress syndrome (2006) (12)
- The puzzle of long-term morbidity after critical illness (2010) (12)
- Nighttime Intensivist Staffing and Mortality Among Critically Ill Patients (2013) (12)
- Design and rationale of the Procalcitonin Antibiotic Consensus Trial (ProACT), a multicenter randomized trial of procalcitonin antibiotic guidance in lower respiratory tract infection (2017) (12)
- Epidemiology of Readmissions After Sepsis Hospitalization in Children. (2019) (12)
- The influence of high-frequency jet ventilation with varying cardiac-cycle specific synchronization on cardiac output in ARDS. (1997) (12)
- In vivo quantification of rolling and adhered leukocytes in human sepsis (2018) (12)
- Successful Resuscitation From In-Hospital Cardiac Arrest--What Happens Next? (2015) (11)
- Critical care medicine training and certification for emergency physicians. (2005) (11)
- Whether to Intubate During Cardiopulmonary Resuscitation: Conventional Wisdom vs Big Data. (2017) (11)
- Heterogeneity of Treatment Effect: Estimating How the Effects of Interventions Vary Across Individuals. (2021) (11)
- Prospective Evaluation of Coronavirus Disease 2019 (COVID-19) Vaccine Responses Across a Broad Spectrum of Immunocompromising Conditions: the COVID-19 Vaccination in the Immunocompromised Study (COVICS) (2022) (11)
- Duration and Magnitude of Hypotension and Monocyte Deactivation in Patients With Community-Acquired Pneumonia (2011) (11)
- Pediatric Outcomes After Regulatory Mandates for Sepsis Care (2020) (11)
- Genetic epidemiology of sepsis and septic shock. (2004) (11)
- National Shortages of Generic Sterile Injectable Drugs: Norepinephrine as a Case Study of Potential Harm. (2017) (11)
- Reducing variation and standardizing practice in the intensive care unit. (2001) (11)
- A Comparison of Free-Standing versus Co-Located Long-Term Acute Care Hospitals (2015) (11)
- Default options in advance directives: study protocol for a randomised clinical trial (2016) (11)
- Relationship between Race and the Effect of Fluids on Long‐term Mortality after Acute Respiratory Distress Syndrome. Secondary Analysis of the National Heart, Lung, and Blood Institute Fluid and Catheter Treatment Trial (2017) (11)
- The United States critical illness and injury trials group: an introduction. (2009) (10)
- Revisiting Mars and Venus: understanding gender differences in critical illness (2011) (10)
- Impact of monoclonal antibody treatment on hospitalization and mortality among non-hospitalized adults with SARS-CoV-2 infection (2021) (10)
- Erratum to: 36th International Symposium on Intensive Care and Emergency Medicine (2016) (10)
- Identifying Strategies for Effective Telemedicine Use in Intensive Care Units: The ConnECCT Study Protocol (2017) (10)
- Achieving Diagnostic Excellence for Sepsis. (2021) (10)
- Clinical expert round table discussion (session 5) at the Margaux Conference on Critical Illness: outcomes of clinical trials in sepsis: lessons learned. (2001) (10)
- The Acute Dialysis Quality Initiative--part II: patient selection for CRRT. (2002) (10)
- Do intensive care unit patients have intensive care unit physicians? Unfortunately not. (2006) (10)
- Charting (and publishing) the boundaries of critical illness. (2005) (10)
- Author Correction: Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19 from an international collaborative meta-analysis of randomized trials (2021) (9)
- Choosing wisely® in critical care: maximizing value in the intensive care unit. (2014) (9)
- Effect of public reporting on intensive care unit discharge destination and outcomes. (2015) (9)
- How Best to Resuscitate Patients With Septic Shock? (2019) (9)
- Plasma lipid profiling for the prognosis of 90-day mortality, in-hospital mortality, ICU admission, and severity in bacterial community-acquired pneumonia (CAP) (2020) (9)
- Differences in Hospital Risk-standardized Mortality Rates for Acute Myocardial Infarction When Assessed Using Transferred and Nontransferred Patients (2017) (9)
- Strategies to Promote ResiliencY (SPRY): a randomised embedded multifactorial adaptative platform (REMAP) clinical trial protocol to study interventions to improve recovery after surgery in high-risk patients (2020) (9)
- Triage patterns for medicare patients presenting to nontrauma hospitals with moderate or severe injuries. (2015) (9)
- International Comparisons of Intensive Care: Understanding the Differences (2006) (9)
- The Paradox of End-of-Life Hospital Treatment Intensity among Black Patients: A Retrospective Cohort Study. (2018) (9)
- Don’t let perfection be the enemy of the good: it’s time for optimism over the role of severity scoring systems in intensive care unit performance measurement (2000) (9)
- Transportation characteristics associated with non-arrivals to paediatric clinic appointments: a retrospective analysis of 51 580 scheduled visits (2017) (9)
- Assessing Outcomes in Critical Care (2002) (9)
- Protocol and Fidelity Monitoring Plan for Four Supports. A Multicenter Trial of an Intervention to Support Surrogate Decision Makers in Intensive Care Units (2018) (8)
- Brain MR imaging and spectroscopy for outcome prognostication after pediatric cardiac arrest. (2020) (8)
- Tuberculosis, nontuberculous lung infection, pleural disorders, pulmonary function, respiratory muscles, occupational lung disease, pulmonary infections, and social issues in AJRCCM in 2004. (2005) (8)
- Trying to Improve Sepsis Care in Low-Resource Settings. (2017) (8)
- Creating an infrastructure for comparative effectiveness research in emergency medical services. (2014) (8)
- Procalcitonin-Guided Antibiotic Use. (2018) (8)
- Design of a multi-arm randomized clinical trial with no control arm. (2016) (8)
- County-Level Effects of Prehospital Regionalization of Critically Ill Patients: A Simulation Study* (2015) (7)
- Launching a comparative effectiveness adaptive platform trial of monoclonal antibodies for COVID-19 in 21 days (2021) (7)
- Critical care in AJRCCM 2004. (2005) (7)
- Sedation Management for Critically Ill Children with Pre‐Existing Cognitive Impairment (2019) (7)
- Nighttime Intensivist Staffing And Mortality In Critically Ill Patients (2012) (7)
- Diagnoses Associated with the Delivery of Mechanical Ventilation in the Newborn † 1199 (1997) (7)
- UNDERSTANDING POST‐DISCHARGE MORTALITY AFTER PROLONGED MECHANICAL VENTILATION (1995) (7)
- Can Scoring Systems Assess ICU Performance? (1998) (7)
- The Acute Physiology and Chronic Health Evaluation II. Article of Knaus et al with expert commentary by Dr Derek Angus. (2007) (7)
- Epidemiology of Sepsis and Non-Infectious SIRS (2009) (7)
- Cost of surviving sepsis: a novel model of recovery from sepsis in Drosophila melanogaster (2016) (6)
- Choosing wisely in critical care: maximizing value in the ICU. (2014) (6)
- Discourse on Method: Measuring the Value of New Therapies in Intensive Care (1998) (6)
- Reflections on Critical Care’s Past, Present, and Future (2021) (6)
- Graph Theoretical Analysis of Genome-Scale Data: Examination of Gene Activation Occurring in the Setting of Community-Acquired Pneumonia (2017) (6)
- No longer the "expensive scare unit"? (2004) (6)
- Protocolized resuscitation with esophageal Doppler monitoring may improve outcome in post-cardiac surgery patients (2005) (6)
- Characteristics and Outcomes of US Patients Hospitalized With COVID-19. (2021) (6)
- Protocol for a randomised trial of an interprofessional team-delivered intervention to support surrogate decision-makers in ICUs (2020) (6)
- Design and rationale of the "Sedation strategy and cognitive outcome after critical illness in early childhood" study. (2018) (6)
- Optimal approach to improving trauma triage decisions: a cost-effectiveness analysis. (2012) (6)
- Dichloroacetate-induced metabolic reprogramming improves lifespan in a Drosophila model of surviving sepsis (2020) (6)
- EPIDEMIOLOGY OF MECHANICAL VENTILATION NONINFANT US CHILDREN: Research Citation X (2002) (6)
- Developing a shared sepsis data infrastructure: a systematic review and concept map to FHIR (2022) (6)
- Power Calculations to Select Instruments for Clinical Trial Secondary Endpoints. A Case Study of Instrument Selection for Post‐Traumatic Stress Symptoms in Subjects with Acute Respiratory Distress Syndrome (2017) (6)
- Variation in sepsis care: a wake-up call (2003) (5)
- Feasibility of Embedding a Scalable, Virtually Enabled Biorepository in the Electronic Health Record for Precision Medicine (2021) (5)
- Prediction of outcome in critically ill patients (1998) (5)
- Applying Syndemic Theory to Acute Illness. (2021) (5)
- Study Design Issues in Sepsis Trials (2000) (5)
- Defining the representativeness heuristic in trauma triage: A retrospective observational cohort study (2019) (5)
- The Effect of Intensive Care Unit Admission Patterns on Mortality-based Critical Care Performance Measures. (2016) (5)
- Assessing intensive care unit performance: a new conceptual framework (2000) (5)
- PROGRESS (Promoting Global Research Excellence in Severe Sepsis): A Preliminary Report of an International Internet-Based Sepsis Registry (2003) (5)
- Association Between State Medicaid Expansion and Emergency Access to Acute Care Hospitals in the United States (2020) (5)
- Prehospital identification of community sepsis using biomarkers of host response (2020) (4)
- Protocolized Sedation vs Usual Care in Pediatric Patients Mechanically Ventilated for Acute Respiratory Failure: A Randomized Clinical Trial (2016) (4)
- Discharge Destination As a Marker of Mobility Impairment in Survivors of Acute Respiratory Distress Syndrome. (2019) (4)
- Rising use of intensive care unit services in Medicare (2005) (4)
- OUTCOME PREDICTION WITH THE APACHE II SYSTEM IN LIVER TRANSPLANTATION (1993) (4)
- ICU USE AT THE END-OF-LIFE IN US CHILDREN: Research Citation CC (2002) (4)
- A cluster-randomised trial of a multifaceted quality improvement intervention in Brazilian intensive care units (Checklist-ICU trial): statistical analysis plan. (2015) (4)
- Association of Practitioner Interfacility Triage Performance With Outcomes for Severely Injured Patients With Fee-for-Service Medicare Insurance. (2019) (4)
- Multidisciplinary acute care research organization (MACRO): If you build it, they will come (2013) (4)
- Clinical Criteria to Identify Patients With Sepsis--Reply. (2016) (4)
- 1504: IMMUNE CHECKPOINT INHIBITORS IN SEPSIS A PHASE 1B TRIAL OF ANTI-PD-L1 (BMS-936559) (2018) (4)
- Assessing the Importance Placed on End-of-Life Treatment in the Intensive-Care Unit (2004) (4)
- Longer-Term Outcomes of the ProACT Trial. (2020) (4)
- Emergency department implementation of monoclonal antibody infusion for the treatment of coronavirus disease 2019: A template for rapid deployment (2021) (4)
- Molecular biology for today's practicing intensivist. (2005) (4)
- Towards Understanding Pathophysiology in Critical Care: The Human Body as a Complex System (2001) (4)
- 1: Proadrenomedullin in Emergency Department Patients With Community-Acquired Pneumonia (2008) (4)
- US Hospital Capacity Managers’ Experiences and Concerns Regarding Preparedness for Seasonal Influenza and Influenza-like Illness (2021) (4)
- Acute care practices relevant to quality end-of-life care: a survey of Pennsylvania hospitals (2010) (4)
- Association of Metformin Use During Hospitalization and Mortality in Critically Ill Adults With Type 2 Diabetes Mellitus and Sepsis* (2022) (4)
- An Exploratory Assessment of Serum Biomarkers of Post-Cardiac Arrest Syndrome in Children. (2021) (4)
- Ongoing Use of Pulmonary Artery Catheters Despite Negative Trial Findings. (2016) (4)
- CHANGES IN INCIDENCE, MANAGEMENT, AND CARE OF PEDIATRIC STATUS ASTHMATICUS OVER THE LAST DECADE.: 13 (2005) (4)
- Determining the value of critical care (1999) (3)
- How should we Measure the Economic Consequences of Critical Illness (2003) (3)
- Thrombolytic therapy for acute myocardial infarction: GUSTO criticized. (1994) (3)
- Selective decontamination of the digestive tract: a meta-analysis (1994) (3)
- Does Preexisting Practice Modify How Video Games Recalibrate Physician Heuristics in Trauma Triage? (2019) (3)
- National intensive care unit datasets: lost at sea without a compass? (1999) (3)
- Update in critical care 2005. (2006) (3)
- MATRIX METALLOPROTEINASE (MMP)-8 IS CRITICAL In A MURINE MODEL OF SEPSIS As Well As IN PATIENTS WITH COMMUNITY- ACQUIRED PNEUMONIA (CAP)-ASSOCIATED SEPSIS (2010) (3)
- The Molecular Genetics of Sepsis: Clinical Epidemiology Considerations (2000) (3)
- Using incentives to recruit physicians into behavioral trials: lessons learned from four studies (2017) (3)
- Author Correction: Adaptive platform trials: definition, design, conduct and reporting considerations (2019) (3)
- Predictive Validity of the qSOFA Score for Sepsis in Adults with Community-Onset Staphylococcal Infection in Thailand (2019) (3)
- An official American thoracic society statement: position statement on ATS activities for the promotion of respiratory and sleep/wake health and the care of the critically ill in the United States. (2009) (3)
- THROMBOLYTIC THERAPY FOR ACUTE MYOCARDIAL INFARCTION : GUSTO CRITICIZED. AUTHORS REPLY (1994) (3)
- RACIAL VARIATION IN THE INCIDENCE, ICU UTILIZATION, AND MORTALITY OF SEVERE SEPSIS: 35 (2004) (3)
- Long-term Economic Consequences of Surviving Intensive Care (2003) (3)
- Understanding the Incidence and Long-term Outcome of ARDS (1997) (3)
- Interferon-associated left ventricular dysfunction in a liver transplant recipient (1996) (3)
- CONTINUOUS VERSUS INTERMITTENT RENAL REPLACEMENT THERAPY: IS THERE A DIFFERENCE IN SURVIVAL? (1999) (3)
- Towards better care: an exploration of some barriers and solutions to research transfer in the intensive care unit. (2003) (3)
- Understanding the lingering consequences of what we treat and what we do (2004) (3)
- The Epidemiology of Extremity Threat and Amputation Following Vasopressor-dependent Sepsis. (2021) (3)
- Predicting disease progression using dynamic microsimulation in pneumonia-related sepsis (2005) (2)
- Relationship Between Ventilator-Free-Days And Patient-Centered Outcomes In Patients With Acute Lung Injury (2012) (2)
- THE FIRST YEAR AFTER ARDS: RESULTS OF A MULTI-CENTER STUDY (1999) (2)
- Quantifying Risk in Sepsis: A Review of Illness Severity and Organ Dysfunction Scoring (2002) (2)
- End-at-lite Care in the ICU: Commonalities and Differences between North America and Europe (2010) (2)
- Epidemiology of Sepsis Among Adolescents at Community Hospital Emergency Departments: Implications for Rory’s Regulations (2017) (2)
- 1379: BLUE LIGHT THERAPY MODULATES THE SYSTEMIC RESPONSE TO SEPSIS IN MICE AND HUMANS (2016) (2)
- Acute and chronic neurologic outcomes of non-neurologic critical illness. (2005) (2)
- Recognition of Sepsis in Resource-Limited Settings (2019) (2)
- ICU use of haloperidol prior to the 2002 SCCM sedation and analgesia guidelines (2004) (2)
- A cluster randomized trial of a multifaceted quality improvement intervention in Brazilian intensive care units: study protocol. (2015) (2)
- ICU Capacity Strain On The Day Of Admission Increases The Risk Of In-Hospital Death (2012) (2)
- The epidemiology of severe sepsis in newborns, infants, and children in the U.S. (2002) (2)
- Drotrecogin Alfa (Activated) (2020) (2)
- Interstitial lung disease, lung cancer, lung transplantation, pulmonary vascular disorders, and sleep-disordered breathing in AJRCCM in 2004. (2005) (2)
- Association Between Intravenous Fluid Bolus and Biomarker Trajectory During Prehospital Care (2020) (2)
- The apache II system in orthotopic liver transplantation over-estimates mortality (1993) (2)
- The New Shape of Intensive Care in the USA (2013) (2)
- GENERATING TISS-28 SCORES DIRECTLY FROM HOSPITAL BILLING DATA: VALIDATION ON NEW HOSPITAL DATA (1998) (2)
- ID4: THE CONFUSION BETWEEN SEPTICEMIA AND SEVERE SEPSIS (2001) (2)
- International Survey of Critically Ill Children With Acute Neurologic Insults: The PANGEA study (2017) (2)
- Evidence for expanding physician supply. (2005) (2)
- Economic Evaluation of New Therapies in Sepsis (2001) (2)
- 329 Use of a Modified Trauma Score in the Prehospital Assessment of Disaster Victims (1993) (2)
- HOW VARIABLE IS ICU RESOURCE USE ACROSS US HOSPITALS?: 33 (2004) (2)
- The Search for Effective Therapy for Sepsis (2017) (2)
- Multicenter Randomized Trial of the Four Supports Intervention for Surrogate Decision Makers in ICUs (2020) (2)
- Racial Disparities in Infection and Sepsis: Does Biology Matter? (2008) (1)
- JAMA Peer Reviewers in 2020. (2021) (1)
- Early goal-directed therapy in the treatment of sepsis: response to comments by Jaehne et al. (2015) (1)
- Long-term mortality after mechanical ventilation (1996) (1)
- Estimated frequency of nursing facility-acquired pneumonia? (2003) (1)
- 1659. Variation in Identifying Sepsis and Organ Dysfunction Using Administrative Versus Clinical Data and Impact on Hospital Outcome Comparisons (2018) (1)
- Outcomes after a Digital Behavior Change Intervention to Improve Trauma Triage: An Analysis of Medicare Claims. (2021) (1)
- The future of critical care. (2005) (1)
- PRELIMINARY EVALUATION OF SIMBABY, A NOVEL PEDIATRIC SIMULATOR: 229 (2004) (1)
- QS383. Calcium/Calmodulin-Dependent Protein Kinase IV Mediates Nucleocytoplasmic Shuttling and Release of HMGB1 During LPS Stimulation of Macrophages (2008) (1)
- Recall of clinical trial participation and attrition rates in survivors of acute respiratory distress syndrome (2021) (1)
- Stimulation of Macrophages HMGB 1 during Lipopolysaccharide Nucleocytoplasmic Shuttling and Release of Kinase ( CaMK ) IV Mediates Calcium / Calmodulin-Dependent Protein (2008) (1)
- COMPARISON OF ICU RESOURCES IN THE UNITED STATES AND UNITED KINGDOM.: 123-M (2005) (1)
- 753: SIRS IS PREVALENT IN EARLY SAH AND IS ASSOCIATED WITH WORSE GCS AND HIGHER MORTALITY (2016) (1)
- IS THE MANAGEMENT OF SEVERE TBI IN CHILDREN IN THE US APPROPRIATELY REGIONALIZED?: 51 (2002) (1)
- Association of EEG and Blood-Based Brain Injury Biomarker Accuracy to Prognosticate Mortality After Pediatric Cardiac Arrest: An Exploratory Study. (2022) (1)
- Structures And Processes Of Care In Intensivist-Staffed Critical Care Units (2011) (1)
- Physicians' and Family Members' Perception of a Family Support Intervention in Intensive Care Units (2020) (1)
- TRENDS IN HOSPITAL DISPOSITION AMONG MEDICARE BENEFICIARIES ADMITTED TO THE ICU IN THE LAST 90 DAYS OF LIFE: 39 (2004) (1)
- Validity of the qSOFA Score in Low- and Middle-Income Countries-Reply. (2018) (1)
- Risk and Setting for Multiple Organ Failure in Medical Patients (2000) (1)
- Early, Goal-Directed Therapy for Septic Shock - A Patient-Level Meta-Analysis. (2017) (1)
- Sepsis Phenotypes Are Dynamic and Associated with Long-Term Outcomes (2020) (1)
- What's in a day? (2005) (1)
- Hypothesis Generation: Asking the Right Question, Getting the Correct Answer (2002) (1)
- Selepressin for Patients With Septic Shock-Reply. (2020) (1)
- 730: SIRS IS PREVALENT IN ICH AND IS ASSOCIATED WITH MORTALITY (2016) (1)
- Comprar Oxford Textbook Of Critical Care 2nd Ed. | Andrew Webb | 9780199600830 | OXFORD (2016) (1)
- TRENDS IN ICU USE AMONG MEDICARE BENEFICIARIES IN THE LAST 90 DAYS OF LIFE: 40 (2004) (1)
- Commentary Severe sepsis epidemiology: sampling, selection, and society (2004) (1)
- Prevalence of long-term decision regret and associated risk factors in a large cohort of ICU surrogate decision makers (2023) (1)
- Use of Intensive Care at the End of Life in the United States: The authors reply (2004) (1)
- Sepsis Bundles and Mortality Among Pediatric Patients-Reply. (2018) (1)
- Judging hospitals for care of all critically ill patients versus care of all intensive care unit patients: Is there a difference? (2015) (1)
- 58: A FEASIBILITY TRIAL TO DETECT SEPSIS IN THE ED BASED UPON BLOOD MONOCYTE VOLUME VARIABILITY (2015) (1)
- A Novel Ensemble Learning Approach to Understand Heterogeneity of Treatment Effect in Critical Care Trials (2020) (1)
- 312 Prehospital Deaths in Three Earthquakes (1993) (1)
- Modeling reality: new methods to better mimic biologic processes and improve outcome prediction in critical illness. (2004) (1)
- Understanding the Role of Heuristics in Physician Non-Compliance with Trauma Triage Guidelines (2014) (1)
- Macroeconomics of the ICU (1999) (1)
- Determining the optimal approach to improving trauma triage decisions: a cost-effectiveness analysis (2013) (1)
- 1408: GENETIC VARIANTS ASSOCIATED WITH HYPERINFLAMMATION IN SEPTIC SHOCK (2016) (1)
- Electronic Health Records as Sources of Research Data--Reply. (2016) (1)
- 1345: SERIAL EVALUATION OF QSOFA AMONG PATIENTS WITH SUSPECTED INFECTION (2016) (1)
- The Impact of Chronic Disease on Response to Infection (2007) (1)
- Identifying Sepsis Phenotypes-Reply. (2019) (1)
- Mortality As a Measure of Treatment Effect in Clinical Trials Recruiting Critically Ill Patients* (2023) (1)
- Protocol for a two-arm pragmatic stepped-wedge hybrid effectiveness-implementation trial evaluating Engagement and Collaborative Management to Proactively Advance Sepsis Survivorship (ENCOMPASS) (2021) (1)
- Staffing intensive care units with critical care physicians may improve clinical outcomes (2003) (1)
- ProPACC: Protocol for a Trial of Integrated Specialty Palliative Care for Critically Ill Older Adults. (2022) (1)
- EFFECTIVENESS OF USING HUMAN SIMULATION FOR DIFFICULT AIRWAY MANAGEMENT TRAINING: 247 (2004) (0)
- What's the Cost of Mechanical Ventilation of the Newborn in the US? 1139 (1997) (0)
- Epidemiology of Surgical Amputation After Sepsis (2019) (0)
- Chapter 5 – Proving the Point: Evidence-Based Medicine in Pediatric Critical Care (2011) (0)
- Fibroblast growth factor 23, a novel biomarker to detect severe sepsis (2015) (0)
- Measuring Performance on the ABCDEF Bundle During Interprofessional Rounds via a Nurse-Based Assessment Tool. (2023) (0)
- Trajectories Of Physical Disability And Cognitive Decline And The Risk Of Severe Sepsis Hospitalizations In Older Adults: The Cardiovascular Health Study (2012) (0)
- Emotional Health Status After Acute Lung Injury (2011) (0)
- Abstract 154: Serum Biomarkers of Brain Injury Predict Outcome After Pediatric Cardiac Arrest (2011) (0)
- Reach and Acceptability of Novel Educational Strategies in the ICU (2020) (0)
- Randomized Controlled Trials in Critical Care Medicine. Authors' reply (2008) (0)
- Novel Trial Design in Sepsis (2018) (0)
- Severe sepsis and septic shock. (2013) (0)
- Organizational characteristics, outcomes and resource use in ICUs: the ORCHESTRA Study (2015) (0)
- Reply to: Physiology is Vital to Precision Medicine in ARDS and Sepsis. (2022) (0)
- Chapter 6 – Proving the Point: Evidence-Based Medicine in Pediatric Critical Care (2006) (0)
- Selection of patients for acute extracorporeal renal support in general and CRRT in particular (2000) (0)
- 1007: ORGAN SUPPORT-BASED SURROGATE OUTCOME MEASURE FOR SEPSIS TRIALS (2015) (0)
- A Novel Approach To Studying The Impact Of Pro-Domain Stability On Matrix Metalloproteinase Activation (2011) (0)
- 676: MONITORING AND THERAPEUTIC PRACTICE PATTERNS IN PEDIATRIC NEUROCRITICAL CARE (2020) (0)
- Acting on Imperfect Information: When to Rely on Observational Data. (2016) (0)
- Corrigendum to "Design of a multi-arm randomized clinical trial with no control arm" [Contemporary Clinical Trials 46 (2016) 12-17]. (2016) (0)
- Biologically active versus immunoreactive high-mobility group box 1 (2007) (0)
- Epidemiology of Reported Antimicrobial Allergy During Prehospital Care (2019) (0)
- and Mark of End-Stage Liver Disease Incorporating Biological Natural History in Simulation Models : Empirical Estimates of the Progression (2005) (0)
- CRISIS IN CRITICAL CARE The Demand for Critical Care Services is Increasing Critical care (2005) (0)
- Vector control to eliminate artemisinin resistant malaria in the Greater Mekong subregion (2014) (0)
- 1: Procalcitonin in Emergency Department Patients with Suspected Community-Acquired Pneumonia: Results From the GenIMS (Genetic and Inflammatory Markers of Sepsis) Study (2006) (0)
- Perceived Effectiveness of Novel Education Strategies Promoting Preventive Post-Extubation Noninvasive Ventilation in the ICU (2020) (0)
- Criteria Help Predict Course? Systemic Inflammatory Response Syndrome Pneumonia: When Does It Happen, and Do Severe Sepsis in Community-Acquired (2007) (0)
- 810: IMPROVING RISK CLASSIFICATION OF CRITICAL ILLNESS WITH BIOMARKERS (2012) (0)
- Monocyte Distribution Width, an Early Indicator of Sepsis-3 in High Risk Emergency Department Patients (2019) (0)
- ICU admission and discharge criteria-Oxford Medicine (2022) (0)
- Critical Care from 50,000 Feet (2006) (0)
- Abstracts of the American College of Emergency Physicians (ACEP) Research Forum 2008, Scientific Assembly. August 27-28, 2008. Chicago, Illinois, USA. (2008) (0)
- 185: HYPEROXIC INJURY AND INNATE IMMUNITY IN DROSOPHILA MELANOGASTER (2012) (0)
- Prognosis of Mortality in Bacterial Community Acquired Pneumonia (CAP) Using Metabolomics (fatty Acids and Lipids) as Potential Biomarkers (2019) (0)
- Evidence-Based Critical Care (2011) (0)
- Therapy guided by pulmonary-artery catheter for high-risk surgical patients was not better than standard care. (2003) (0)
- Management of parenchymal haemorrhage. (2016) (0)
- A(H1N1) Preparing for the Sickest Patients With 2009 Influenza (2009) (0)
- Using Metabolomics to Differentiate Positive Blood Culture from Negative Blood Culture in Bacterial Community Acquired Pneumonia (2020) (0)
- Sepsis in Brazilian emergency departments: a prospective multicenter observational study (2023) (0)
- HOW HAVE HOSPITALS ADOPTED TO THE NEW SEVERE SEPSIS ICD-9-CM CODES? ANALYSIS OF US MEDICARE DATA.: 485 (2006) (0)
- 1421: MICROCIRCULATORY RESPONSE TO RESUSCITATION AS A PREDICTOR OF ACUTE KIDNEY DISEASE IN SEPTIC SHOCK (2020) (0)
- 119: GEOGRAPHIC ACCESS TO SEVERE ARDS REFERRAL CENTERS IN THE UNITED STATES (2013) (0)
- Hospitalization For Pneumonia Is Associated With Increased Risk Of Dementia In Older Adults (2012) (0)
- Point-of-care sensors for the management of sepsis (2018) (0)
- Postgraduate Training in Disaster Medicine (1997) (0)
- Advances in transplantation (1992) (0)
- Commentary Variation in sepsis care: a wake-up call (2003) (0)
- Genetic Determinants of Sepsis Outcomes (2014) (0)
- Diagnosis and assessment of stroke. (2016) (0)
- Epidemiology of stroke (2016) (0)
- Nighttime Intensivist Physician Staffing in the ICU (2013) (0)
- Validation Of The Provent 14 Mortality Prediction Model In Patients With Acute Lung Injury Receiving At Least 14 Days Of Mechanical Ventilation (2011) (0)
- Where There's Fire, There's Smoke (2006) (0)
- The authors reply. (2019) (0)
- The timing of new acute hemodynamic events in ICU patients (2004) (0)
- Randomized Controlled Trials in Critical Care Medicine—Reply (2008) (0)
- Using incentives to recruit physicians into behavioral trials: lessons learned from four studies (2017) (0)
- Sepsis Phenotyping Using Clinical and Biomarker Data in the ProCESS Randomized Trial (2019) (0)
- Obituary: Mitchell P. Fink (2015) (0)
- Sepsis and the role of the human host (2003) (0)
- Reply: Validity of the Posttraumatic Stress Symptoms-14 Instrument in Acute Respiratory Failure Survivors. (2017) (0)
- 1085: VASOPRESSIN USE FOR HYPOTENSION IN A TRANSPLANT INTENSIVE CARE UNIT (2016) (0)
- STABILITY OF HOSPITAL UTILIZATION RATES WHILE AWAITING LIVER TRANSPLANTATION (1999) (0)
- Pulmonary and Critical Care Updates Update in Critical Care 2006 (2007) (0)
- The authors reply. (2014) (0)
- USING THE RUSSELL EQUATION IN DIFFERENT CASE MIX POPULATIONS AND HOSPITAL TYPES: 118 (2004) (0)
- 1338: HOSPITAL-LEVEL VARIATION IN RISK-ADJUSTED MORTALITY FOR PEDIATRIC SEPSIS (2016) (0)
- PATIENTS WITH ACUTE KIDNEY DYSFUNCTION AT ICU ADMISSION HAVE WORSE SURVIVAL COMPARED TO PATIENTS WITH SUBSEQUENT ACUTE KIDNEY DYSFUNCTION.: 263-S (2005) (0)
- Human Factors and ICU Outcomes (2003) (0)
- Shock II (2011) (0)
- Macrophage migration inhibitory factor and multiple organ dysfunction syndrome (2009) (0)
- Epidemiology and Patterns of Chronic β-Blocker Use During Intensive Care (2020) (0)
- Early goal-directed therapy versus “early”, “goal-directed” therapy: response to comments by Saleh (2015) (0)
- DISEASE SPECIFIC CHANGES IN TOTAL BILIRUBIN IN PATIENTS ON THE WAITING LIST FOR LIVER TRANSPLANT. (1999) (0)
- Reply: Risk-based Heterogeneity of Treatment Effect in Trials and Implications for Surveillance of Clinical Effectiveness Using Regression Discontinuity Designs. (2015) (0)
- Sepsis Assessment And Identification In Low Resource Settings: The Sailors Study (2017) (0)
- Revising Host Phenotypes of Sepsis Using Microbiology (2021) (0)
- A Role for Cyclooxygenase-1 in Neuropathic Pain? (2003) (0)
- Is There a Survival Advantage of Admission to a High Intensity Hospital (2007) (0)
- FACTORS THAT PREDICT UNDERTRIAGE TO TERTIARY CARE FOR CHILDREN WITH SEVERE TRAUMATIC BRAIN INJURY: 5 (2004) (0)
- Idiopathic vs Hereditary Pancreatitis (2003) (0)
- Prehospital Characteristics of Clinical Sepsis Phenotypes Identified at Emergency Department Presentation (2019) (0)
- Reply. Severe sepsis: stay and play or scoop and run? (2013) (0)
- JAMA Peer Reviewers in 2004 (2016) (0)
- PREDICTING LONG-TERM OUTCOMES OF PROLONGED MECHANICAL VENTILATION (MV): 399 (2004) (0)
- 199: Between-country and Between-specialty Differences in Approach to Early Septic Shock (2007) (0)
- Oxygen Therapy in the ICU. Reply. (2020) (0)
- Review: Selective decontamination of the digestive tract reduces respiratory tract infections in intensive care patients (1992) (0)
- Invited commentary on Sepsis (2022) (0)
- Validation of a computerized therapeutic intervention scoring system (1995) (0)
- Title Protocolized sedation vs usual care in pediatric patients mechanically ventilated for acute respiratory failure : A randomized clinical trial Permalink (2015) (0)
- THE INFLUENCE OF SELECTION BIAS ON THE COST EFFECTIVENESS OF HUMAN ANTI-ENDOTOXIN ANTIBODY (HA-1A) (1993) (0)
- Public Health Disaster? The Lingering Consequences of Sepsis: A Hidden (2010) (0)
- Reply to Goligher et al.: Physiology Is Vital to Precision Medicine in Acute Respiratory Distress Syndrome and Sepsis (2022) (0)
- Update in critical care 2006. (2007) (0)
- Red Blood Cell Transfusion And Long-Term Outcomes After Acute Lung Injury (2011) (0)
- An exploratory assessment of the management of pediatric traumatic brain injury in three centers in Africa (2022) (0)
- Let’s Be Splitters, Rather Than “Lumpers”: The authors reply (2004) (0)
- Representativeness of Severe Injury Increases Likelihood of Appropriate Transfer to Trauma Centers (2018) (0)
- Do Findings of High Mortality From Pneumonia in the Elderly Make It the Old Man's Friend?—Reply (2004) (0)
- [Acute renal dysfunction: it's time to speak appropriately!]. (2009) (0)
- Authors' response. (2014) (0)
- 365: CHARACTERISTICS OF LONG STAY PATIENTS IN PEDIATRIC INTENSIVE CARE UNITS IN THE UNITED STATES (2014) (0)
- JAMA Peer Reviewers for 2003 (2017) (0)
- PREDICTING LATE TRANSFUSION REQUIREMENTS IN THE CRITICALLY ILL: 37 (2004) (0)
- 299 Effect of Building Type on Risk of Death Following the 1992 Earthquake in Turkey (1993) (0)
- Relationship of insurance type and treatment of severe status asthmaticus in working-age adults (2004) (0)
- New recommendations for the use of corticosteroids in sepsis: Not so fast! (2008) (0)
- 16: DROSOPHILA MODEL OF SEPSIS AND AGEING (2012) (0)
- TRENDS IN HOSPITALIZED COMMUNITY-ACQUIRED PNEUMONIA: RELEVANCE TO RESOURCE ALLOCATION (1998) (0)
- Modeling and Uncertainty in Cost-effectiveness Analyses of Sepsis Therapies (2006) (0)
- Community Sepsis in Patients with High Risk for Resistant Organisms: Epidemiology and Outcomes (2020) (0)
- Reply: The Effect of Hypoxia–Hypercapnia on Neuropsychological Function in Adult Respiratory Distress Syndrome (2012) (0)
- EFFECTS OF AGE AND GENDER ON MORTALITY OF BLUNT CHEST TRAUMA PATIENTS: 302 (2004) (0)
- CHANGES IN CRITICAL CARE RESOURCE USE DURING MASSIVE HEALTH CARE REFORMS: 34 (2004) (0)
- Free Papers (2004) (0)
- 54: MONOCYTE DISTRIBUTION WIDTH A NOVEL INDICATOR OF SEPSIS-2 AND SEPSIS-3 IN HIGH-RISK ED PATIENTS (2019) (0)
- Racial Differences in Rates of Severe Sepsis—Reply (2010) (0)
- What's Next? Unraveling Severe Sepsis: Why Did OPTIMIST Fail and (2010) (0)
- The Relative Importance of Unmeasured Covariates in Racial/Ethnic Disparities Research (2008) (0)
- Domains of Usefulness ( and subdomains ) for Potential sepsis Diagnostic Criteria and their Priority by Purpose (2016) (0)
- Adults with septic shock and extreme hyperferritinemia exhibit pathogenic immune variation (2018) (0)
- Power Calculations to Select Instruments for Clinical Trial Secondary Endpoints: A Case Study of Instrument Selection for Post-Traumatic Stress Symptoms in Subjects with ARDS. (2016) (0)
- HUMAN ANTI-ENDOTOXIN ANTIBODY (HA-1A) FOR GRAM NEGATIVE SEPSIS: CUMULATIVE EXPERIENCE OVER A 15 MONTH PERIOD AT A SINGLE INSTITUTION (1992) (0)
- 186: EXPLORATORY STUDY OF DURATION OF HYPOTHERMIA FOR NEUROPROTECTION AFTER PEDIATRIC CARDIAC ARREST (2015) (0)
- 1651. The Impact of the 2017–2018 Influenza Season on Acute Care Hospitals in the United States: A Qualitative Evaluation of Immediate Responses and Future Preparedness (2019) (0)
- Validation of an automated index of intensive care resource utilization generated from hospital billing data (1996) (0)
- THE EFFECT OF ICU CULTURE ON PATIENT OUTCOMES-A US MULTICENTER STUDY.: 6 (2005) (0)
- 127: Calcium supplementation induces cytokine production through calcium/calmodulin-dependent protein kinases (CaMK) in an in vivo cecal ligation and puncture (CLP) model of sepsis (2007) (0)
- The authors reply. (2017) (0)
- Commentary Understanding the lingering consequences of what we treat and what we do (2004) (0)
- 1191: HETEROGENEITY IN RESPONSE TO EARLY GOAL-DIRECTED THERAPY IN SEPSIS (2022) (0)
- Clinical Evidence Generation During a Pandemic (2022) (0)
- COST AND LONG‐TERM OUTCOME OF PROLONGED VENTILATION (1995) (0)
- The Epidemiology and Outcome of Patients with Sepsis: Clear as Mud (2000) (0)
- Room G, 10/16/2000 2: 00 PM - 4: 00 PM (PS) Does an Intensivist Improve Outcomes in Critically Ill Patients? A Systematic Review A-434 (2000) (0)
- Choice of resuscitation fluids (2016) (0)
- NHLBI WORKSHOP Identifying Clinical Research Priorities in Adult Pulmonary and Critical Care NHLBI Working Group Report (2020) (0)
- 366: COST ANALYSIS OF THE PANGEA STUDY (2014) (0)
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