Detlef Schuppan
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German biochemist and physician
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(Suggest an Edit or Addition)According to Wikipedia, Detlef Schuppan is a German biochemist and physician. He focuses on the diagnosis and treatment of coeliac disease and wheat sensitivity, fibrotic liver diseases and the immunology of chronic diseases and cancer. He is the director of the Institute of Translational Immunology and a professor of internal medicine, gastroenterology, and hepatology at the Medical Center of the Johannes Gutenberg University of Mainz in Germany. He directs the outpatient clinic for coeliac disease and small intestinal diseases. He is also a professor of medicine and a senior visiting scientist at Harvard Medical School.
Detlef Schuppan's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Identification of tissue transglutaminase as the autoantigen of celiac disease (1997) (2002)
- Serum markers detect the presence of liver fibrosis: a cohort study. (2004) (1038)
- Autoantibodies to tissue transglutaminase as predictors of celiac disease. (1998) (616)
- Celiac disease: from pathogenesis to novel therapies. (2009) (586)
- Wheat amylase trypsin inhibitors drive intestinal inflammation via activation of toll-like receptor 4 (2012) (544)
- Current concepts of celiac disease pathogenesis. (2000) (537)
- Evolving therapies for liver fibrosis. (2013) (535)
- Matrix as a modulator of hepatic fibrogenesis. (2001) (517)
- Hepatic fibrosis: Concept to treatment. (2015) (505)
- Chemical, pharmacological and clinical profile of the East Asian medical plant Centella asiatica. (2000) (483)
- Liver cirrhosis (2008) (478)
- Non-Celiac Gluten Sensitivity: The New Frontier of Gluten Related Disorders (2013) (439)
- The role of macrophages in nonalcoholic fatty liver disease and nonalcoholic steatohepatitis (2018) (419)
- Diagnosis of Non-Celiac Gluten Sensitivity (NCGS): The Salerno Experts’ Criteria (2015) (414)
- IL28B genotype is associated with differential expression of intrahepatic interferon‐stimulated genes in patients with chronic hepatitis C (2010) (397)
- Structure of the extracellular matrix in normal and fibrotic liver: collagens and glycoproteins. (1990) (375)
- Herbal medicine in the treatment of liver diseases. (2007) (374)
- Update on Serologic Testing in Celiac Disease (2010) (322)
- Hedgehog signaling regulates epithelial-mesenchymal transition during biliary fibrosis in rodents and humans. (2008) (319)
- Herbal hepatotoxicity. (2005) (317)
- Herbal products for liver diseases: A therapeutic challenge for the new millennium (1999) (310)
- Silymarin retards collagen accumulation in early and advanced biliary fibrosis secondary to complete bile duct obliteration in rats (1997) (301)
- Targeting liver fibrosis: Strategies for development and validation of antifibrotic therapies (2009) (294)
- World Gastroenterology Organisation global guidelines on celiac disease. (2013) (293)
- Etiologies and predictors of diagnosis in nonresponsive celiac disease. (2007) (291)
- In situ hybridization for procollagen types I, III and IV mRNA in normal and fibrotic rat liver: Evidence for predominant expression in nonparenchymal liver cells (1989) (291)
- Determinants of fibrosis progression and regression in NASH. (2018) (282)
- Differential expression of matrix-metalloproteinase-1 and -2 genes in normal and fibrotic human liver. (1994) (265)
- The good and the bad collagens of fibrosis – Their role in signaling and organ function (2017) (265)
- Liver fibrosis: Direct antifibrotic agents and targeted therapies. (2018) (264)
- Transforming growth factors beta 1 and beta 2 are differentially expressed in fibrotic liver disease. (1991) (262)
- Factors that Influence Adherence to a Gluten-Free Diet in Adults with Celiac Disease (2008) (241)
- Confocal endomicroscopy shows food-associated changes in the intestinal mucosa of patients with irritable bowel syndrome. (2014) (240)
- Mdr2 (Abcb4)-/- mice spontaneously develop severe biliary fibrosis via massive dysregulation of pro- and antifibrogenic genes. (2005) (238)
- A simple validated gluten-free diet adherence survey for adults with celiac disease. (2009) (235)
- Characterization of integrin receptors in normal and neoplastic human brain. (1993) (235)
- Nutritional Wheat Amylase-Trypsin Inhibitors Promote Intestinal Inflammation via Activation of Myeloid Cells. (2017) (231)
- Non‐alcoholic steatohepatitis: Pathogenesis and novel therapeutic approaches (2013) (224)
- Tissue inhibitor of metalloproteinase-1 and -2 RNA expression in rat and human liver fibrosis. (1997) (219)
- Hepatitis C and liver fibrosis (2003) (214)
- Anti-tumor necrosis factor-alpha monoclonal antibody therapy in severe alcoholic hepatitis. (2003) (209)
- Kinetics of the histological, serological and symptomatic responses to gluten challenge in adults with coeliac disease (2012) (207)
- Selective targeting of lysyl oxidase-like 2 (LOXL2) suppresses hepatic fibrosis progression and accelerates its reversal (2017) (206)
- Fibroblast growth factor 21 limits lipotoxicity by promoting hepatic fatty acid activation in mice on methionine and choline-deficient diets. (2014) (204)
- Antibodies to tissue transglutaminase as serologic markers in patients with dermatitis herpetiformis. (1999) (198)
- Nonceliac gluten sensitivity. (2015) (198)
- Cost effectiveness of peginterferon α-2b plus ribavirin versus interferon α-2b plus ribavirin for initial treatment of chronic hepatitis C (2003) (197)
- Vascular endothelial growth factor promotes fibrosis resolution and repair in mice. (2014) (193)
- Procollagen expression by nonparenchymal rat liver cells in experimental biliary fibrosis. (1990) (190)
- When is a coeliac a coeliac? Report of a working group of the United European Gastroenterology Week in Amsterdam, 2001. (2001) (190)
- A histone deacetylase inhibitor, trichostatin A, suppresses myofibroblastic differentiation of rat hepatic stellate cells in primary culture (1999) (190)
- Novel insights into the function and dynamics of extracellular matrix in liver fibrosis. (2015) (187)
- EUS-guided alcohol ablation of an insulinoma. (2006) (183)
- Inhibition of integrin alphavbeta6 on cholangiocytes blocks transforming growth factor-beta activation and retards biliary fibrosis progression. (2008) (182)
- Acupuncture and Moxibustion in the Treatment of Active Crohn’s Disease: A Randomized Controlled Study (2004) (178)
- Cellular localization of type I III and IV procollagen gene transcripts in normal and fibrotic human liver. (1990) (175)
- Air Pollution and Climate Change Effects on Allergies in the Anthropocene: Abundance, Interaction, and Modification of Allergens and Adjuvants (2017) (171)
- Hepatitis induced by Kava (Piper methysticum rhizoma). (2003) (168)
- The Overlapping Area of Non-Celiac Gluten Sensitivity (NCGS) and Wheat-Sensitive Irritable Bowel Syndrome (IBS): An Update (2017) (166)
- The histone-deacetylase inhibitor Trichostatin A blocks proliferation and triggers apoptotic programs in hepatoma cells. (2002) (166)
- Collagens in the liver extracellular matrix bind hepatocyte growth factor. (1998) (165)
- Pathomechanisms in celiac disease. (2005) (165)
- Duodenal Bacteria From Patients With Celiac Disease and Healthy Subjects Distinctly Affect Gluten Breakdown and Immunogenicity. (2016) (165)
- Mouse Models of Nonalcoholic Steatohepatitis: Toward Optimization of Their Relevance to Human Nonalcoholic Steatohepatitis (2019) (164)
- Integrin alphavbeta6 is a marker of the progression of biliary and portal liver fibrosis and a novel target for antifibrotic therapies. (2008) (164)
- Circulating microparticles as disease-specific biomarkers of severity of inflammation in patients with hepatitis C or nonalcoholic steatohepatitis. (2012) (163)
- Targeting the epidermal growth factor receptor by gefitinib for treatment of hepatocellular carcinoma. (2004) (162)
- Activation of tumor-specific T lymphocytes by radio-frequency ablation of the VX2 hepatoma in rabbits. (2003) (162)
- Comparison of Gene Expression Patterns Between Mouse Models of Nonalcoholic Fatty Liver Disease and Liver Tissues From Patients. (2016) (161)
- Lysyl oxidase activity contributes to collagen stabilization during liver fibrosis progression and limits spontaneous fibrosis reversal in mice (2016) (158)
- Pharmacological inhibition of integrin αvβ3 aggravates experimental liver fibrosis and suppresses hepatic angiogenesis (2009) (156)
- Mass-encoded synthetic biomarkers for multiplexed urinary monitoring of disease (2012) (155)
- An oral endothelin-A receptor antagonist blocks collagen synthesis and deposition in advanced rat liver fibrosis. (2000) (155)
- Antifibrotic effect of silymarin in rat secondary biliary fibrosis is mediated by downregulation of procollagen alpha1(I) and TIMP-1. (2001) (153)
- Ciprofloxacin induces apoptosis and inhibits proliferation of human colorectal carcinoma cells (2002) (151)
- EGFR blockade by cetuximab alone or as combination therapy for growth control of hepatocellular cancer. (2005) (151)
- Proliferating bile duct epithelial cells are a major source of connective tissue growth factor in rat biliary fibrosis. (2001) (151)
- Successful Targeting to Rat Hepatic Stellate Cells Using Albumin Modified with Cyclic Peptides That Recognize the Collagen Type VI Receptor* (2000) (150)
- Hepatitis C virus-replicating hepatocytes induce fibrogenic activation of hepatic stellate cells. (2005) (148)
- Cocarcinogenic effects of alcohol in hepatocarcinogenesis (2002) (147)
- Erlotinib induces cell cycle arrest and apoptosis in hepatocellular cancer cells and enhances chemosensitivity towards cytostatics. (2005) (146)
- The cysteine-rich region of dipeptidyl peptidase IV (CD 26) is the collagen-binding site. (1995) (146)
- Acute hepatitis induced by greater celandine (Chelidonium majus). (1999) (145)
- Pentoxifylline downregulates profibrogenic cytokines and procollagen I expression in rat secondary biliary fibrosis (2002) (142)
- A prospective comparative study of five measures of gluten‐free diet adherence in adults with coeliac disease (2007) (141)
- Progression of liver fibrosis in post-transplant hepatitis C: mechanisms, assessment and treatment. (2013) (137)
- Many Patients With Irritable Bowel Syndrome Have Atypical Food Allergies Not Associated With Immunoglobulin E. (2019) (136)
- A randomized, placebo-controlled trial of emricasan in patients with NASH and F1-F3 fibrosis. (2019) (135)
- Immunohistochemical distribution of collagens types IV, V, and VI and of pro-collagens types I and III in human alveolar bone and dentine. (1986) (134)
- Ito cell heterogeneity: Desmin‐negative ito cells in normal rat liver (1994) (124)
- The Incidence and Clinical Spectrum of Refractory Celiac Disease in a North American Referral Center (2011) (122)
- The receptor for advanced glycation end products is highly expressed in the skin and upregulated by advanced glycation end products and tumor necrosis factor-alpha. (2006) (122)
- Enhanced liver fibrosis test for the non-invasive diagnosis of fibrosis in patients with NAFLD: A systematic review and meta-analysis. (2020) (122)
- The leukocyte integrin Mac-1 (CD11b/CD18) contributes to binding of human granulocytes to collagen. (1995) (121)
- Macrophage-mediated phagocytosis of apoptotic cholangiocytes contributes to reversal of experimental biliary fibrosis. (2010) (119)
- The hedgehog pathway regulates remodelling responses to biliary obstruction in rats (2008) (118)
- Soluble Collagen VI Drives Serum-starved Fibroblasts through S Phase and Prevents Apoptosis via Down-regulation of Bax* (1999) (118)
- Extrahepatic platelet-derived growth factor-β, delivered by platelets, promotes activation of hepatic stellate cells and biliary fibrosis in mice. (2014) (117)
- Type I, II, III, IV, V, and VI Collagens Serve as Extracellular Ligands for the Isoforms of Platelet-derived Growth Factor (AA, BB, and AB)* (1996) (117)
- Blockade of IGF-1 receptor tyrosine kinase has antineoplastic effects in hepatocellular carcinoma cells. (2006) (117)
- Kupffer cell–derived 95‐kd type IV collagenase/gelatinase B: Characterization and expression in cultured cells (1995) (116)
- Comparable expression of matrix metalloproteinases 1 and 2 in pouchitis and ulcerative colitis (2000) (116)
- Tissue transglutaminase does not affect fibrotic matrix stability or regression of liver fibrosis in mice. (2011) (116)
- Activation and dramatically increased cytolytic activity of tumor specific T lymphocytes after radio-frequency ablation in patients with hepatocellular carcinoma and colorectal liver metastases. (2006) (114)
- Cellular localization of procollagen gene transcripts in inflammatory bowel diseases. (1992) (114)
- Trichostatin A, a histone deacetylase inhibitor, suppresses collagen synthesis and prevents TGF-beta(1)-induced fibrogenesis in skin fibroblasts. (2002) (112)
- Undulin, an extracellular matrix glycoprotein associated with collagen fibrils. (1990) (111)
- Increased collagen type III synthesis by fibroblasts isolated from strictures of patients with Crohn's disease. (1992) (111)
- Silymarin: A Review of its Clinical Properties in the Management of Hepatic Disorders (2001) (110)
- Fibrogenesis and fibrolysis in collagenous colitis. Patterns of procollagen types I and IV, matrix-metalloproteinase-1 and -13, and TIMP-1 gene expression. (1999) (109)
- Alcohol dehydrogenase 1C*1 allele is a genetic marker for alcohol‐associated cancer in heavy drinkers (2006) (109)
- American Journal of Physiology: Gastrointestinal and Liver Physiology American Journal of Physiology: Heart and Circulatory Physi- QlQgY American Journal of Physiology: Regulatory, Integrative and Comparative Physiology American Journal of Physiology: Renal, Fluid and Electrolyte (2003) (108)
- Growth factor receptors and related signalling pathways as targets for novel treatment strategies of hepatocellular cancer. (2008) (106)
- Nonalcoholic steatohepatitis: the therapeutic challenge of a global epidemic (2011) (106)
- Mortality Excess in Individuals with Elevated IgA Anti-Transglutaminase Antibodies: The KORA/MONICA Augsburg Cohort Study 1989–1998 (2006) (106)
- Liver fibrosis: Common mechanisms and antifibrotic therapies. (2015) (106)
- Effects of nintedanib on the microvascular architecture in a lung fibrosis model (2017) (105)
- Cancer-associated circulating large extracellular vesicles in cholangiocarcinoma and hepatocellular carcinoma. (2017) (105)
- Plasma Pro‐C3 (N‐terminal type III collagen propeptide) predicts fibrosis progression in patients with chronic hepatitis C (2015) (104)
- Targeting dexamethasone to Kupffer cells: Effects on liver inflammation and fibrosis in rats (2001) (104)
- Failure of fibrotic liver regeneration in mice is linked to a severe fibrogenic response driven by hepatic progenitor cell activation. (2013) (103)
- Halofuginone Induces Matrix Metalloproteinases in Rat Hepatic Stellate Cells via Activation of p38 and NFκB* (2006) (103)
- Sublethal heat treatment promotes epithelial‐mesenchymal transition and enhances the malignant potential of hepatocellular carcinoma (2013) (103)
- The integrated value of serum procollagen III peptide over time predicts hepatic hydroxyproline content and stainable collagen in a model of dietary cirrhosis in the rat (1989) (101)
- Nutritional therapy in alcoholic liver disease (2003) (101)
- Autoantibodies to tissue transglutaminase are sensitive serological parameters for detecting silent coeliac disease in patients with Type 1 diabetes mellitus (2000) (100)
- Anti-fibrotic therapy: lost in translation? (2012) (100)
- HIV and HCV Cooperatively Promote Hepatic Fibrogenesis via Induction of Reactive Oxygen Species and NFκB* (2010) (100)
- Celiac crisis is a rare but serious complication of celiac disease in adults. (2010) (99)
- Acupuncture and Chinese herbal medicine in the treatment of patients with seasonal allergic rhinitis: a randomized‐controlled clinical trial (2004) (98)
- Differential modulation of rat hepatic stellate phenotype by natural and synthetic retinoids (2004) (98)
- Human T cell microparticles circulate in blood of hepatitis patients and induce fibrolytic activation of hepatic stellate cells (2011) (98)
- Suppression of T cell-mediated injury in human gut by interleukin 10: role of matrix metalloproteinases. (1998) (98)
- Identification of Rothia Bacteria as Gluten-Degrading Natural Colonizers of the Upper Gastro-Intestinal Tract (2011) (97)
- Low prevalence of hepatitis C virus infection in porphyria cutanea tarda in germany (1995) (97)
- Acupuncture and moxibustion in the treatment of ulcerative colitis: A randomized controlled study (2006) (96)
- Non-celiac wheat sensitivity: differential diagnosis, triggers and implications. (2015) (95)
- Matrix metalloproteinase pattern in celiac duodenal mucosa (2005) (94)
- Precision-cut liver slices: a tool to model the liver ex vivo. (2013) (92)
- Novel engineered targeted interferon‐gamma blocks hepatic fibrogenesis in mice (2011) (92)
- Collagen VI regulates normal and transformed mesenchymal cell proliferation in vitro. (1996) (91)
- Endothelial GLP-1 (Glucagon-Like Peptide-1) Receptor Mediates Cardiovascular Protection by Liraglutide In Mice With Experimental Arterial Hypertension (2019) (91)
- Integrin αvβ6 critically regulates hepatic progenitor cell function and promotes ductular reaction, fibrosis, and tumorigenesis (2016) (91)
- Differential expression of collagen types I, III, and IV by fat-storing (Ito) cells in vitro. (1992) (89)
- Efficacy and tolerability of pegylated IFN-alpha in patients with neuroendocrine gastroenteropancreatic carcinomas. (2006) (88)
- Targeting myeloid cells in the tumor sustaining microenvironment. (2017) (88)
- The cultivable human oral gluten-degrading microbiome and its potential implications in coeliac disease and gluten sensitivity. (2013) (87)
- Risk factors and outcome of 107 patients with decompensated liver disease and acute renal failure (including 26 patients with hepatorenal syndrome): the role of hemodialysis. (1995) (87)
- Specific hepatic delivery of procollagen α1(I) small interfering RNA in lipid‐like nanoparticles resolves liver fibrosis (2015) (86)
- A validated disease-specific symptom index for adults with celiac disease. (2009) (86)
- Transglutaminases in inflammation and fibrosis of the gastrointestinal tract and the liver. (2009) (85)
- Variants of bcl-2 specific siRNA for silencing antiapoptotic bcl-2 in pancreatic cancer (2005) (85)
- Cross linking to tissue transglutaminase and collagen favours gliadin toxicity in coeliac disease (2005) (85)
- Serum procollagen peptides and collagen type VI for the assessment of activity and degree of hepatic fibrosis in schistosomiasis and alcoholic liver disease (1992) (84)
- TGFβ1 in liver fibrosis: time to change paradigms? (2001) (84)
- A chondroitin/dermatan sulfate form of CD44 is a receptor for collagen XIV (undulin). (1996) (83)
- Predictors of advanced fibrosis in non‐cirrhotic non‐alcoholic fatty liver disease in Germany (2018) (82)
- Discovery of a Novel and Rich Source of Gluten-Degrading Microbial Enzymes in the Oral Cavity (2010) (82)
- Radioimmunoassay for the carboxy-terminal cross-linking domain of type IV (basement membrane) procollagen in body fluids. Characterization and application to collagen type IV metabolism in fibrotic liver disease. (1986) (81)
- Increased collagen type III synthesis by fibroblasts isolated from strictures of patients with Crohn's disease (1992) (81)
- Lactobacilli Degrade Wheat Amylase Trypsin Inhibitors to Reduce Intestinal Dysfunction Induced by Immunogenic Wheat Proteins. (2019) (80)
- Diagnostic accuracy of elastography and magnetic resonance imaging in patients with NAFLD: a systematic review and meta-analysis. (2021) (80)
- Celiac disease: epidemiology, pathogenesis, diagnosis, and nutritional management. (2005) (79)
- The clinical utility of biomarkers and the nonalcoholic steatohepatitis CRN liver biopsy scoring system in patients with nonalcoholic fatty liver disease (2009) (79)
- Hepatocyte transplantation activates hepatic stellate cells with beneficial modulation of cell engraftment in the rat (2005) (79)
- Cell cycle arrest and apoptosis induction in hepatocellular carcinoma cells by HMG-CoA reductase inhibitors. Synergistic antiproliferative action with ligands of the peripheral benzodiazepine receptor. (2005) (78)
- Use of HOMA-IR to diagnose non-alcoholic fatty liver disease: a population-based and inter-laboratory study (2017) (78)
- Effect of HMG-CoA reductase inhibitors on proliferation and protein synthesis by rat hepatic stellate cells. (2001) (77)
- Gluten and the Gut--Lessons for Immune Regulation (2002) (76)
- Exposing gliadin as a tasty food for lymphocytes (1998) (76)
- The immune contexture of hepatocellular carcinoma predicts clinical outcome (2018) (76)
- Temporal and spatial patterns of transin/stromelysin RNA expression following toxic injury in rat liver (1991) (76)
- Collagen and tissue turnover as a function of age: Implications for fibrosis. (2016) (74)
- Outcome measures in coeliac disease trials: the Tampere recommendations (2018) (74)
- VEGF induces proliferation, migration, and TGF-beta1 expression in mouse glomerular endothelial cells via mitogen-activated protein kinase and phosphatidylinositol 3-kinase. (2005) (74)
- Regulatory effects of stem cell factor and interleukin-4 on adhesion of human mast cells to extracellular matrix proteins. (2002) (74)
- Macrophage recruitment by fibrocystin‐defective biliary epithelial cells promotes portal fibrosis in congenital hepatic fibrosis (2016) (73)
- Collagen biology and non‐invasive biomarkers of liver fibrosis (2020) (73)
- Discontinuities in triple helical sequence Gly—X—Y of basement membrane (type IV) collagen (1980) (73)
- Traditional Chinese Medicine (TCM) for fibrotic liver disease: hope and hype. (2014) (72)
- Cylindrical Brush Polymers with Polysarcosine Side Chains: A Novel Biocompatible Carrier for Biomedical Applications (2015) (72)
- The histone-deacetylase inhibitor SAHA potentiates proapoptotic effects of 5-fluorouracil and irinotecan in hepatoma cells (2005) (72)
- Wheat Amylase Trypsin Inhibitors as Nutritional Activators of Innate Immunity (2015) (72)
- Differential regulation of extracellular matrix synthesis during liver regeneration after partial hepatectomy in rats (1999) (72)
- Sorafenib alone or as combination therapy for growth control of cholangiocarcinoma. (2007) (71)
- MMPs in the gut: inflammation hits the matrix (2000) (69)
- IL-4 Receptor Alpha Signaling through Macrophages Differentially Regulates Liver Fibrosis Progression and Reversal (2018) (69)
- Radioimmunoassay for human type VI collagen and its application to tissue and body fluids. (1985) (69)
- Hemochromatosis (HFE) gene mutations and response to chloroquine in porphyria cutanea tarda. (2003) (69)
- Lysyl Oxidase (LOX) Family Members: Rationale and Their Potential as Therapeutic Targets for Liver Fibrosis (2020) (68)
- Hepatotoxicity of alcohol‐induced polar retinol metabolites involves apoptosis via loss of mitochondrial membrane potential (2005) (68)
- Pathomechanisms in Celiac Disease (2003) (68)
- Involvement of cyclooxygenase (COX)-2 products in acceleration of ulcer healing by gastrin and hepatocyte growth factor. (2000) (68)
- Keratin variants associate with progression of fibrosis during chronic hepatitis C infection (2006) (67)
- Distribution of undulin, tenascin, and fibronectin in the human periodontal ligament and cementum: comparative immunoelectron microscopy with ultra-thin cryosections. (1993) (67)
- Hepatic fibrosis: From bench to bedside (2002) (66)
- Influence of low FODMAP and gluten-free diets on disease activity and intestinal microbiota in patients with non-celiac gluten sensitivity. (2019) (66)
- Clinical Guide and Update on Porphyrias. (2019) (66)
- Antifibrotic Therapies in the Liver (2015) (65)
- Cellular localization of laminin gene transcripts in normal and fibrotic human liver. (1989) (65)
- All-trans and 9-cis retinoic acid alter rat hepatic stellate cell phenotype differentially (1999) (65)
- Effect of Local Application of Growth Factors on Gastric Ulcer Healing and Mucosal Expression of Cyclooxygenase-1 and -2 (2001) (64)
- Transient elastography compared to serum markers to predict liver fibrosis in a cohort of Chinese patients with chronic hepatitis B (2015) (64)
- Heterogeneity of liver cells expressing procollagen types I and IV in vivo (1997) (64)
- Celiac Disease and its Link to Type 1 Diabetes Mellitus (2001) (64)
- Evaluating the antifibrotic potency of galunisertib in a human ex vivo model of liver fibrosis (2017) (63)
- Serum concentration of the aminoterminal procollagen type III peptide in the rat reflects early formation of connective tissue in experimental liver cirrhosis. (1986) (63)
- Autoantibodies of patients with coeliac disease are insufficient to block tissue transglutaminase activity (2003) (63)
- Strategies and endpoints of antifibrotic drug trials: Summary and recommendations from the AASLD Emerging Trends Conference, Chicago, June 2014 (2015) (62)
- Ergebnisse einer S2k-Konsensuskonferenz der Deutschen Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselerkrankungen (DGVS) gemeinsam mit der Deutschen Zöliakie-Gesellschaft (DZG) zur Zöliakie, Weizenallergie und Weizensensitivität (2014) (62)
- Histone deacetylase inhibitor MS-275 alone or combined with bortezomib or sorafenib exhibits strong antiproliferative action in human cholangiocarcinoma cells. (2007) (62)
- Interaction between psychiatric and autoimmune disorders in coeliac disease patients in the Northeastern United States (2009) (62)
- Immunoelectron microscopic localization of collagens type I, V, VI and of procollagen type III in human periodontal ligament and cementum. (1991) (62)
- Fibrogenesis assessed by serological type III collagen formation identifies patients with progressive liver fibrosis and responders to a potential antifibrotic therapy. (2016) (62)
- The challenge of developing novel pharmacological therapies for non‐alcoholic steatohepatitis (2009) (61)
- Quantitative testing of liver function in relation to fibrosis in patients with chronic hepatitis B and C. (2001) (61)
- Connective tissue polypeptides in serum as parameters to monitor antifibrotic treatment in hepatic fibrogenesis. (1991) (60)
- Matrix Metalloproteinases in Necrotising Enterocolitis (2003) (60)
- Serum hyaluronate correlates with histological progression in alcoholic liver disease (2003) (60)
- Antiproliferative and proapoptotic effects of histone deacetylase inhibitors on gastrointestinal neuroendocrine tumor cells. (2006) (60)
- The immunohistochemical distribution of collagens type IV, V, VI and of laminin in the human oral mucosa. (1986) (59)
- Collagens Serve as an Extracellular Store of Bioactive Interleukin 2* (2000) (58)
- Localization of a Binding Site for the Proteoglycan Decorin on Collagen XIV (Undulin)* (1997) (58)
- Circulating autoantibodies to tissue transglutaminase differentiate patients with dermatitis herpetiformis from those with linear IgA disease. (1999) (58)
- Undulin is a novel member of the fibronectin-tenascin family of extracellular matrix glycoproteins. (1991) (58)
- Broad-Spectrum Matrix Metalloproteinase Inhibition Curbs Inflammation and Liver Injury but Aggravates Experimental Liver Fibrosis in Mice (2010) (57)
- Hepatocytes as a source of collagen type XVIII endostatin (1998) (57)
- Circulating levels of angiogenic cytokines can predict tumour progression and prognosis in neuroendocrine carcinomas (2005) (57)
- Targeting Cancer Associated Fibroblasts in Liver Fibrosis and Liver Cancer Using Nanocarriers (2020) (57)
- Gliptins Suppress Inflammatory Macrophage Activation to Mitigate Inflammation, Fibrosis, Oxidative Stress, and Vascular Dysfunction in Models of Nonalcoholic Steatohepatitis and Liver Fibrosis. (2018) (56)
- Serum aminoterminal type III procollagen peptide (1988) (55)
- Celiac disease and endocrine autoimmunity - the genetic link. (2018) (55)
- Immunohistochemical investigation of collagen subtypes in human glioblastomas (2004) (55)
- Wheat amylase‐trypsin inhibitors exacerbate intestinal and airway allergic immune responses in humanized mice (2019) (55)
- Reciprocal modulation of matrix metalloproteinase-13 and type I collagen genes in rat hepatic stellate cells. (2003) (53)
- C282Y and H63D mutation of the hemochromatosis gene in German porphyria cutanea tarda patients (2001) (53)
- Additive antitumour response to the rabbit VX2 hepatoma by combined radio frequency ablation and toll like receptor 9 stimulation (2011) (53)
- Human myofibroblastlike cells obtained by outgrowth are representative of the fibrogenic cells in the liver (1995) (53)
- Optimized Mouse Models for Liver Fibrosis. (2017) (52)
- Serum Collagen Type VI and XIV and Hyaluronic Acid as Early Indicators for Altered Connective Tissue Turnover in Alcoholic Liver Disease (2001) (52)
- Comparison of transient elastography, serum markers and clinical signs for the diagnosis of compensated cirrhosis (2010) (52)
- Dendritic cells in liver injury and fibrosis: shortcomings and promises. (2013) (52)
- Collagen type I and III occur together in hybrid fibrils in the space of disse of normal rat liver (1990) (52)
- Ferrocenyl-Coupled N-Heterocyclic Carbene Complexes of Gold(I): A Successful Approach to Multinuclear Anticancer Drugs. (2016) (52)
- Remodeling of extracellular matrix in gastric ulceration (2001) (52)
- In situ ablation of experimental liver metastases delays and reduces residual intrahepatic tumour growth and peritoneal tumour spread compared with hepatic resection (2002) (52)
- Pharmacological inhibition of the vitronectin receptor abrogates PDGF-BB-induced hepatic stellate cell migration and activation in vitro. (2007) (51)
- Monitoring nonresponsive patients who have celiac disease. (2006) (51)
- Soluble collagen VI induces tyrosine phosphorylation of paxillin and focal adhesion kinase and activates the MAP kinase erk2 in fibroblasts. (1999) (50)
- Acute Hepatitis Induced by Greater Celandine (Chelidonium majus) (2003) (50)
- Temporal and spatial patterns of proto-oncogene expression at early stages of toxic liver injury in the rat. (1991) (50)
- The role of the immune response against tissue transglutaminase in the pathogenesis of coeliac disease. (2004) (50)
- Targeted therapy of liver fibrosis/cirrhosis and its complications. (2011) (50)
- Innate immunity and coeliac disease (2003) (50)
- Structure of mouse type IV collagen (1986) (49)
- Acetaldehyde regulates the gene expression of matrix-metalloproteinase-1 and -2 in human fat-storing cells. (1994) (49)
- Distribution and cellular origin of collagen VI during development and in cirrhosis. (1992) (49)
- Influence of aldosterone on collagen synthesis and proliferation of rat cardiac fibroblasts (2001) (49)
- Hepatocyte growth factor in human osteoarthritic cartilage. (1999) (49)
- Human Intestinal Fibroblasts Prevent Apoptosis in Human Intestinal Mast Cells by a Mechanism Independent of Stem Cell Factor, IL-3, IL-4, and Nerve Growth Factor12 (2004) (48)
- Prognosis of a large cohort of patients with hepatocellular carcinoma in a single European centre. (2002) (48)
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- P634 THE ROLE OF IL-4 RECEPTOR ALPHA IN ALTERNATIVE MACROPHAGE ACTIVATION AND DURING FIBROSIS PROGRESSION AND REVERSAL (2014) (0)
- Mo1052 - Confocal Endomicroscopy (CLE) Based Double Blind Randomized Controlled Cross-Over Study Provides Objective Measurement of Food Sensitivity in IBS Patients, their Somatization, Anxiety and Depression (2018) (0)
- Alfabeta3 and altabeta6-integrin antagonists as anti-fibrotic agents (2004) (0)
- Cell Microparticles: A Novel Marker of Hepatic Inflammation and Progression in Patients With HCV or NASH (2011) (0)
- Combination therapy with biomodulating agents induces apoptosis and changes of p21cip/waf and pro-caspase 3 expression in hepatoma cells in vitro (2001) (0)
- Focal activation of ECE-1 isoforms in acute and chronic liver injury in fibrogenesis (2001) (0)
- Synthesis and secretion of undulin by rat liver fat storing (ITO-) cells (1991) (0)
- 822 – Further Development of a Novel In Vivo Model For Celiac Disease in Mice with a Humanized Immune System (2019) (0)
- Combination therapy of hepatocellular carcinoma with biological modulators is a promising pro-apoptopic treatment in vitro (2001) (0)
- Nutritional wheat alpha-amylase/trypsin inhibitors (ATIs) favor the development of murine autoimmune encephalopathy (2015) (0)
- Decline in NASH and atherosclerosis-associated oxidised phospholipids and 7-ketocholesterol in response to icosabutate therapy (2020) (0)
- Celiac Disease and its Manifold Manifestations (2019) (0)
- MHC polymorphism and diseases (WS-088) Chairpersons: Yasuharu Nishimura, Narinder Mehra (2010) (0)
- Subject Index Vol. 50, 1988 (1988) (0)
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- 267 Serum concentrations of MMP-2 and TIMP-1 are of independent prognostic value for cancer specific survival in patients with metastatic colorectal carcinomas under chemotherapy (2003) (0)
- 194 Cirrhosis reversal by antifibrotic combination therapy: Potentiation of the antifibrotic effect of mycophenolate mofetil by pioglitazone and halofuginone (2006) (0)
- Icosabutate: targeting metabolic and inflammatory pathways for the treatment of NASH (2022) (0)
- Anti-tumoral efficacy of four different histone deacetylase inhibitors on hepatoma cells in vitro (2003) (0)
- Sa1991 Nutritional Wheat Alpha-Amylase/Trypsin Inhibitors (ATIs) Worsen Allergic Airway Inflammation in Mice (2014) (0)
- Sa1314 Histologic and Serologic Kinetics in Adults With Celiac Disease Undergoing Gluten Challenge (2012) (0)
- Nanoparticular bisphosphonate induces an anti-fibrotic response by modulation of fibrosis associated genes and pathways in (non-) parenchymal liver cells in CCL4 fibrotic mice (2020) (0)
- Tu1243 MATRIX METALLOPROTEINASE 8 (MMP-8) DEFICIENCY RENDERS MICE RESISTANT TO DSS-INDUCED COLONIC INFLAMMATION (2020) (0)
- Suppression of hepatic fibrosis by efficient Col1a1 silencing using shRNA inducible mouse models (2017) (0)
- 79 The role of genetic polymorphisms of matrixmetallo-proteinase-3 and transforming growth factor beta-1 in alcoholic liver cirrhosis (2004) (0)
- Comment on “Sourdough Fermentation Degrades Wheat Alpha-Amylase / Trypsin Inhibitor (ATI) and Reduces Pro-Inflammatory Activity”. Foods 2020, 9 , 943. (2020) (0)
- Multiomics Based Association Mapping in Wheat Reveals Genetic Architecture of Quality and Allergenic Related Proteins (2023) (0)
- 623 EXCLUSION OF ATYPICAL FOOD ALLERGENS DETECTED BY CONFOCAL ENDOMICROSCOPY IS SUPERIOR TO A LOW FODMAP DIET IN PATIENTS WITH FOOD-SENSITIVE IBS (2020) (0)
- Effects of nintedanib on the microvascular architecture in a lung fibrosis model (2017) (0)
- Dissecting the molecular antifibrotic effect of the TGF-Beta(I) receptor kinase inhibitor galunisertib in precision-cut liver slices (2016) (0)
- 360 Deficiency of Tissue Transglutaminase Promotes Fibrogenesis and Does Not Facilitate Hepatic Fibrosis Reversal (2008) (0)
- Inducible ablation of TGFß receptor type 2 limited to hepatic stellate cells potently inhibits liver fibrosis and attenuates inflamation (2018) (0)
- Adenosine 2B receptor antagonism alleviates liver fibrosis progression and induces mild fibrosis regression (2012) (0)
- Sa2029 Consumption of Wheat Alpha-Amylase/Trypsin Inhibitors (ATIS) Enhances Experimental Autoimmune Encephalopathy in Mice (2015) (0)
- Immunocytochemical and morphometric analysis of the striated interstitial collagen fibrils in the space of disse of rat and human liver (1987) (0)
- Combination therapy of HCC in a rat model (2004) (0)
- It’s Not Always Wheat! (2019) (0)
- Interplay between metabolic derangement, biomarkers of collagen remodeling and macrophage activation in non-diabetic patients with non-alcoholic fatty liver disease (2020) (0)
- [Indications for liver biopsy in liver tumors]. (2000) (0)
- 25 MICROPARTICLES RELEASED FROM ACTIVATED CD8+ INDUCE FIBROLYTIC GENES IN HEPATIC STELLATE CELLS AND DOWNREGULATE PROCOLLAGEN α1(I) (2009) (0)
- Interplay between metabolic derangement, hepatic fibrogenesis and macrophage activation in non-diabetic patients with non-alcoholic fatty liver disease (2020) (0)
- [Distribution of procollagen transcripts in chronic inflammatory bowel diseases using in situ hybridization]. (1991) (0)
- [763] CRITICAL EVALUATION OF CANDIDATE GENE POLYMORPHISMS IN THE DEVELOPMENT OF ALCOHOLIC LIVER CIRRHOSIS (2007) (0)
- Clinical Spectrum of Refractory Celiac Disease: 273 (2009) (0)
- CCl4-induced liver inflammation and necrosis in mice lacking Tenascin-C (1998) (0)
- A method for inhibiting the expression of a target gene and drug for the treatment of a tumor disease (2002) (0)
- P0418 : Generation and characterization of a myofibroblasts specific conditional Col3a1a-CreERT2 mouse model to study liver fibrosis (2015) (0)
- Nutritional Wheat Amylase Trypsin Inhibitors Exacerbate Gluten-Induced Pathology and Alter the Gut Microbiota in Mice (2017) (0)
- 275 Activation of tumor specific T lymphocytes after radio-frequency ablation in patients with hepatocellular carcinoma and colorectal liver metastases (2004) (0)
- Su1805 – Wheat Amylase/Trypsin Inhibitors Aggravate Eosinophilic Esophagitis (2019) (0)
- Collagen XIV (Undulin) induces quiescence and differentiation in fibroblasts and hepatic stellate cells (2000) (0)
- Classical and Atypical Food Allergies (2019) (0)
- Diet induced hepatic fibrosis in the rat correlation of serum type iii procollagen peptide aniline blue stained hepatic collagen and hepatic hydroxyproline in the presence and absence of 16 16 dimethyl pge 2 (1987) (0)
- Moderate Heat Exposure of HCC Cells Promotes EMT-Like Changes and Accelerates Their Proliferation and Aggressive Potential via Shc-ERK1/2 Signaling (2011) (0)
- 759 STRAIN DIFFERENCES IN MACROPHAGE-MEDIATED CLEARANCE OF DEAD HEPATOCYTES DETERMINE SUSCEPTIBILITY TO LIVER FIBROSIS IN MICE (2009) (0)
- 319 Cholestasis and downregulation of bile acid transporters in a novel in vivo model of sustained non-toxic oxidative stress (H2O2) (2006) (0)
- In Vivo Myofibroblast Specific Gene Silencing in the Liver Using Novel Sirna-Loaded Biodegradable Nanohydrogel Particles (2016) (0)
- 187 Deletion of IL-4Ra on Macrophages Renders Mice Resistant to Intestinal Inflammation (2014) (0)
- Immunological detection method ANTIBODY AGAINST tissue transglutaminase (tTG) ADDRESSED ARE USING tTG FOR THE DIAGNOSIS AND THERAPY MONITORING AND oral pharmaceutical AGENTS CONTAINING tTG (1997) (0)
- Increased Immunohistochemical/PCR Proven Permeability of Duodenal Tight Junctions in Patients with IBS and Wheat Intolerance Initially Shown on Confocal Laser Endomicroscopy (CLE) (2017) (0)
- Effects of willow bark extract on the human immune system (2010) (0)
- Prevalence, severity and patterns of clinicalpractice in outpatient visits for suspected NAFLD – the German CONSTANS STUDY (2018) (0)
- Mo1884 – Dietary Wheat Alpha-Amylase/Trypsin Inhibitors Induce Systemic Low-Grade Inflammation Via Trif-Dependent Pathways (2019) (0)
- P0964 : Direct glucagon-like peptide-1 receptor agonism ameliorates steatohepatitis and fibrosis in models of NASH and biliary fibrosis via regulation of liver macrophage infiltration and activation (2015) (0)
- Rapid Communication Cellular Localization ofLaminin Gene Transcripts inNormal andFibrotic HumanLiver (1989) (0)
- Past, present and future of immunology in Mainz. (2016) (0)
- Immunology of the Intestine (2019) (0)
- [454] TARGETED IDENTIFICATION OF IRON REGULATED GENES IN PATIENTS WITH HEMOCHROMATOSIS AND HEPATITIS C USING A CUSTOM-MADE WHOLE GENOME cDNA MICROARRAY (2007) (0)
- [Significant modification of the hyperthermic effect by starch microspheres (Spherex) of laser-induced hypertheria in the rat liver metastasis model]. (1998) (0)
- INVOLVED IN CHRONIC INFLAMMATORY PROCESSES USING SINGLE MOLECULE LOCALIZATION MICROSCOPY IN CELLS (2017) (0)
- Tu1419 Dietary Wheat Alpha-Amylase/Trypsin Inhibitors Promote Disease Progression in Murine Systemic Lupus Erythematosus (2016) (0)
- Testing safety of germinated rye sourdough in a celiac disease model based on 1 the adoptive transfer of prolamin-primed memory T cells into lymphopenic mice 2 Running Head: Testing food safety for celiac patients in mice (2014) (0)
- Full Title: NON-INVASIVE MARKERS OF LIVER FIBROSIS: ON TREATMENT CHANGES OF SERUM MARKERS PREDICT THE OUTCOME OF ANTI-FIBROTIC THERAPY Authors: (2017) (0)
- Mycofenolate mofetil downregulates TGFβ and procollagen α1(I) and (III) mRNA expression in hepatic stellate cells (2003) (0)
- Disorders of Heme Metabolism (2022) (0)
- 494 - Development of a Novel In Vivo Model for Celiac Disease in Mice with a Fully Humanized Immune System (2018) (0)
- 706 NASH with pericentral fibrosis and neutrophil inflammation in mice overexpressing 11α-Hydroxysteroid-Dehydrogenase (HSD-1) in adipose tissue (2006) (0)
- 282 Hepatocyte growth factor (HGF) inhibits hepatocyte apoptosis in a mouse model of cholestasis (2004) (0)
- Mechanismen der Fibroseprogression bei chronischer Hepatitis C (2004) (0)
- Halofuginone inhibits in vitro migration and proliferation of activated hepatic stellate cells (2003) (0)
- Changes in hepatic hemodynamics after orthotopic liver transplantation: color Doppler sonography (2001) (0)
- FRI-280-Common dietary component, wheat amylase trypsin inhibitors, driver of chronic liver disease in pre-clinical models of NASH and liver fibrosis (2019) (0)
- 1294 Identification and upregulation of the intermediate-conductance CA-activated K (IK) channel in activated rat hepatic stellate cells: specific blockage by charybdotoxin and clotrimazol results in significant reduction of proliferation (2003) (0)
- 323 ADDITIVE ANTI-TUMOR RESPONSE TO THE RABBIT VX2 HEPATOMA BY COMBINED RADIO FREQUENCY ABLATION AND TOLL LIKE RECEPTOR 9 STIMULATION (2012) (0)
- Letter to the editorIncreased prevalence of Helicobacter pylori infection in patients with celiac disease (2000) (0)
- NAFLD and NASH Biomarker Qualification in the LITMUS consortium - Lessons learned. (2022) (0)
- [337] T-CELL DERIVED MEMBRANE MICROPARTICLES INDUCE A PROFIBROLYTIC PHENOTYPE IN HEPATIC STELLATE CELLS (2007) (0)
- Mo1271 Wheat Alpha-Amylase/Trypsin Inhibitors Are Strong Activators of Innate Immunity in Murine and Human Intestinal Tissue Explants (2016) (0)
- 326 Stimulation of interstitial collagenase activity by halofuginone in hepatic stellate cells is dependent on activation of P38 and NF kappa B (2004) (0)
- P1086 : Complex effects of adenosine receptor antagonists in models of liver fibrosis (2015) (0)
- 1307 ANTI-INFLAMMATORY AND DIRECT ANTIFIBROTIC EFFECT OF THE ORAL HEPATOTROPIC DPPIV INHIBITOR LINAGLIPTIN IN A MODEL OF BILIARY FIBROSIS AND NASH (2013) (0)
- Serum microparticles (MPs) as a novel tool to predict hepatocellular carcinoma (HCC) and tumor size (2013) (0)
- HCC Derived Circulating Microparticles Detect Hepatocellular Carcinoma and Differ from Other Cancer Related Microparticles (2016) (0)
- TGF-beta3 plays a prominent role in murine parenchymal liver fibrosis (2020) (0)
- A Prospective Study of Five Measures of Gluten Free Diet Adherence in Adults with Celiac Disease: 228 (2007) (0)
- A PCR protocol to establish standards for routine mycoplasma testing that by design detects over ninety percent of all known mycoplasma species (2023) (0)
- FRI-453-Rapamycin promotes tumoricidal immunity in murine HCC by inducing M1-type macrophages and dentritic cells polarization and enhancement of cytotoxic T-cells (2019) (0)
- Isolated elevation of gGT: what should be the diagnostic approach? (2004) (0)
- GENETIC DELETION OF INTESTINAL ALKALINE PHOSPHATASE ACTIVATES RESIDENT HEPATIC CELLS AND LEADS TO AN INFLUX OF IMMUNE CELLS WITHIN THE LIVER (2009) (0)
- Hepatocyte growth factor (HGF) and proinflammatory cytokines induce gastrin in hepatic cells: an important link in the development of hepatocellular carcinoma (HCC)?? (2003) (0)
- HLA-DQ2 and/or-DQ9 is associated with coeliac disease specific autoantibodies to tissue transglutaminase in families with thyrold autoimmunity (2001) (0)
- Broad-spectrum Matrix Metalloproteinase Inhibition Curbs Inflammation But Aggravates Fibrosis In A Murine Model Of Chronic Carbon Tetrachloride Induced Injury (2009) (0)
- ANTIFIBROTIC THERAPY FOR LIVER FIBROSIS: AN EMERGING REALITY. (2004) (0)
- 567 A functional polymorphism in the glutathione-S-transferase P1 gene determines the progression to cirrhosis in patients with hereditary hemochromatosis (2004) (0)
- Screening for inhibitors of the MMP-2/-9 — Collagen interaction as antifibrotic agents by surface plasmon resonance (2003) (0)
- Overexpression of B7-1 and B7-2 on LFA-1-positive lymphocytes in inflammatory bowel disease (1998) (0)
- Su1807 Nutritional Wheat Alpha-Amylase Trypsin Inhibitors (ATIS) Synergize With a High Fat Diet to Worsen Non-Alcoholic Fatty Liver Disease (2015) (0)
- Attenuated Biliary Fibrosis In Mdr2-/- Mice Fed Omega-3 Fatty Acid-enriched Diet (2009) (0)
- [Tissue transglutaminase as autoantigen in endemic sprue. New aspects in diagnosis and etiopathogenesis]. (1998) (0)
- ACTIVATION OF TUMOR SPECIFIC T LYMPHOCYTES AFTER RADIO-FREQUENCY ABLATION IN PATIENTS WITH HEPATOCELLULAR CARCINOMA AND COLORECTAL LIVER METASTASES (2005) (0)
- 1050 - Wheat Amylase/Trypsin Inhibitors Aggravate Oral Antigen Induced Food Allergy (2018) (0)
- 819 – Metabolism of Wheat Amylase Trypsin Inhibitors by Lactobacilli Ameliorates Gut Dysfunction Induced by Wheat Proteins (2019) (0)
- Anti-in fl ammatory e ff ects of cinnamon extract and identi fi cation of active compounds in fl uencing the TLR2 and TLR4 signaling pathways (2018) (0)
- Clinical impact of heterozygosity for the C282Y and H63D mutation of the hemochromatosis (HFE) gene in chloroquine treated patients with porphyria cutanea tarda (PCT) in Germany (2001) (0)
- Advanced glycation end products (AGE) stimulate the expression of the receptor for AGE (RAGE) in hepatic stellate cells but do not induce cell proliferation and p44/42 MAP kinase activation (2003) (0)
- Kava-induced acute liver injury: A report of 29 novel cases (2003) (0)
- 1261 MICE FED A HIGH-FAT HIGH-FRUCTOSE DIET AND TREATED WITH LOW DOSE STREPTOZOTOCIN DEVELOP INSULIN RESISTANCE, NASH AND LIVER FIBROSIS (2012) (0)
- [189] RESOLUTION OF THIOACETAMIDE-INDUCED LIVER FIBROSIS IN RATS TREATED WITH PENTOXYPHYLLINE (2007) (0)
- Serum fibrosis markers may be more sensitive to predict an antifibrotic effect of interferon alpha in children with chronic hepatitis B (2002) (0)
- Combined antiangiogenic gene therapy with sflt and endostatin is highly effective in a rat model of hepatocellular carcinoma (2004) (0)
- Factor , IL-3 , IL-4 , and Nerve Growth Factor a Mechanism Independent of Stem Cell Apoptosis in Human Intestinal Mast Cells by Human Intestinal Fibroblasts Prevent Schuppan (2003) (0)
- 451 Comparison of liver functional parameters with serum fibrosis markers as predictors of secere necro-inflammation in patients with chronic hepatitis B and D (2004) (0)
- In vivo delivery of siRNA to key transcipts of fibrogenesis in lipid-like carriers inhibits development liver fibrosis (2012) (0)
- T1943 Molecular Imaging of Hepatic Fibrogenesis Using a Nanomolar Affinity Tc-99m-Labeled Small Molecule Trimer Specific for the αVβ6 Integrin (2008) (0)
- Cornea Farinata and other Variants (2009) (0)
- THU-096-Development and validation of true serum biomarkers of liver fibrogenesis ans fibrolysis (2019) (0)
- Bisphosphonate-loaded nanogels attentuate liver fibrosis by repolarization of M2-type macrophages (2022) (0)
- 3D analysis of microvasculature in murine liver fibrosis models using synchrotron radiation-based microtomography (2020) (0)
- Differential expression of tenascin isoforms in acute and chronic human liver injury (1998) (0)
- Dietary wheat amylase trypsin inhibitors activate myeloid cell toll-like receptor 4 to enhance chronic liver disease in murine liver fibrosis and hepatocellular carcinoma (2020) (0)
- THU-088-Serum markers of interstitial matrix formation (PRO-C3) and basement membrane remodeling (PRO-C4 and C4M) predict recurrence of fibrosis and survival in post-liver transplanted patients (2019) (0)
- Exacerbation of Allergic Inflammation in PBMC-Engrafted Humanized Mice by Nutritional Wheat Alpha-Amylase/Trypsin Inhibitors is Mediated by Human IGE and by TLR4 (2017) (0)
- The inactive form of matrix metalloproteinase-9 is stored by liver collagens via the collagenous motive (GLY-PRO-HYP) X (2002) (0)
- On the connective tissue of the human uterine tube: Collagen and glycoproteins (1994) (0)
- Halofuginone stimulates interstitial collagenase activity in HSC via activation of p38 and nuclear factor kappa B (2004) (0)
- Tu1779 – Cinnamon Extract Ameliorates Experimental Colitis Via Attenuation of Tlr4-Related Inflammation and Beneficially Alters Intestinal Microbiota Composition (2019) (0)
- Tissue transglutaminase (tTG)-specific T cell clones in coeliac disease (2005) (0)
- Mo1938 IL-4Ra Deficiency Ameliorates Intestinal Inflammation in Mice and Increases Innate Lymphoid Cells Type 3 (2016) (0)
- P0311 : Balb/c and C57/Bl6 mice exhibit differences in their susceptibility and anti-tumor response to B16F10 melanoma liver metastasis (2015) (0)
- Integrin αvβ6-targeted near-infrared/positron emission tomography contrast agent for liver fibrosis imaging (2018) (0)
- Synergistic inhibition of hepatoma cell proliferation with a combination of 9-cis-retinodd acid, tamoxifene and the angiogenesis inhibitor TNP (2000) (0)
- Tu1780 – Dietary Wheat Amylase Trypsin Inhibitors Modify the Gut Microbiome by Antimicrobial Activity and Aggravates Experimental Colitis (2019) (0)
- Arterial embolisation significantly improves the hyperthermic effect of laser-induced thermotherapy in liver metastasis in rats (1998) (0)
- Double Blind Randomized Controlled Cross-Over Study Using Confocal Endomicroscopy to Differentiate Wheat from Non-Coeliac Gluten Sensitivity (NCGS) in IBS Patients Using Antigen Exclusion vs Sham vs Low Fodmap's Diet to Determine Successful Treatment (2017) (0)
- Su1164 Comparison of Gluten-Degrading Enzyme Activities in Rothia and Kocuria Bacterial Strains (2016) (0)
- High carbohydrate diet induces acute liver injury, enhanced de novo lipogenesis, inflammation and fibrosis but reversible by M2 macrophage polarization (2017) (0)
- Challenge of HLA-DR4,-DQ8, human CD4 triple transgenic NOD mice with gliadin in complete Freund's adjuvant, followed by oral gluten (2006) (0)
- A novel structural glycroprotein associated with collagen fibrils in the liver (1989) (0)
- Sa1398 Immunogenic Gluten Is Modulated by Small Intestinal Bacterial Hydrolysis (2016) (0)
- [367] MEMORY READ OUT OF HYPOXIA-INDUCIBLE FACTOR (HIF) 1 ALPHA AS NOVEL TOOL TO DETERMINE TISSUE OXYGEN: EVIDENCE FOR HYPOXIC HEPATOCELLULAR OXYGEN LEVELS IN VIVO (2007) (0)
- Pharmacokinetics of a sustained release formulation (2018) (0)
- Expression of insulin like growth factor (IGF-II) and of the IGF II receptor (IGF-IIR) in normal and cirrhotic human liver (1998) (0)
- THU-063-Synergistic antifibrotic effect of rapamycin and zoledronic acid in advanced murine biliary fibrosis (2019) (0)
- [134] HYPOXIA-INDUCIBLE FACTOR 1 ALPHA (HIF1) SENSES RAPID HEPATIC OXYGEN DROPS BUT NOT LIVER HYPOXIA IN GENERAL DUE TO AN ADAPTIVE AUTO-LOOP WITH PROLYL HYDROXYLASE 2 (2007) (0)
- 8 Fibrogenesis in PBe (1998) (0)
- Galectin-9 Exhibits Proapoptotic and Antifbrotic Effects on Hepatic Stellate Cells (2011) (0)
- Neurogastroenterology and Motility Histamine causes influx via T-type voltage-gated calcium channels in an enterochromaffin tumor cell line: potential therapeutic target in adverse food reactions (2019) (0)
- 98 CIRCULATING HUMAN INFLAMMATORY CELL MICROPARTICLES (MP): A NOVEL TOOL TO ASSESS SEVERITY OF HEPATIC INFLAMMATION IN HEPATITIS C AND NASH (2011) (0)
- A prospective trial of a gluten free diet in primary sclerosing cholangitis with associated colitis (2022) (0)
- Alcohol-related vitamin A hepatotoxicity is mediated by polar retinoid metabolites and involves apoptosis (2004) (0)
- Temporal and spatial patterns of transin/stromelysin RNA expression following CCL4-intoxication in rat liver (1991) (0)
- Stem cell factor stimulates adhesion of human intestinal mast cells to denatured collagens (2000) (0)
- 160 MicroRNA-199a-5p is Elevated in Experimental Hepatic Fibrosis and Its Inhibition Attenuates Procollagen Type I Expression in Hepatic Stellate Cells (2010) (0)
- P68 A diet rich in wheat alpha-amylase/trypsin inhibitors (ATIs) enhances disease progression in the MRL-Fas(lpr) mouse model of systemic lupus erythematosus (2020) (0)
- Alpha-single chains of collagen type VI inhibit the fibrogenic effects of triple helical collagen VI in hepatic stellate cells (2021) (0)
- Robust anti-Tumor Response in the to the Rabbit VX2 Hepatoma by Combined Radio Frequency Ablation and Toll like Receptor 9 Stimulation (2010) (0)
- GPO10, a collagen analog, effectively promotes activation of collagen‐bound pro‐Matrix‐Metalloproteinase‐2 in fibrotic liver tissue stimulating cell proliferation and migration (2007) (0)
- 38 Activation of tumor specific T lymphocytes after radio-frequency ablation in patients with liver metastases (2003) (0)
- Nutritional Wheat Alpha-Amylase/Trypsin Promote Azoxymethane/Dextran Sulfate Sodium-Induced Colonic Tumorigenesis via Enhancing Mucosal Inflammation (2017) (0)
- Identification of the fast progression and spontaneous regression liver fibrosis phenotypes by a serological collagen turnover profile (2018) (0)
- Cellular Localization ofType1, 111, andIV Procollagen GeneTranscripts in Normal andFibrotic HumanLiver (1990) (0)
- S1603 Microparticles Released from Activated CD8+ But Not CD4+ T Cells Induce Upregulation of Fibrolytic Genes and Downregulation of Procollagen α1(I) in Hepatic Stellate Cells (2009) (0)
- 192 αvβ6 Integrin: an epithelial marker of fibrosis progression and a novel antifibrotic target in experimental and human liver fibrosis (2006) (0)
- Comparable expression of MMP-1 and -2 in pouchitis and ulcerative colitis (1998) (0)
- Zoledronic Acid suppresses tumour associated macrophages andmyeloid derived suppressor cells in murine HCC (2018) (0)
- 194 A Non-Gluten Component of Wheat is a Strong Stimulator of Innate Immune Responses In Vitro and In Vivo and Acts via Toll Like Receptor 4 (2010) (0)
- [Age-dependent distribution of collagen and glycoproteins in the blood vessels of the human uterine tube]. (1997) (0)
- Methods and means for diagnosis and treatment of inflammatory bowel disease (2001) (0)
- Serum procollagen III peptide and hepatic hydroxyproline content (1990) (0)
- IL-4/IL13 Signaling Acts through M2 Macrophages, but not Th2 T Cells or Hepatocytes to Drive Progression of CCL4-Induce Liver Fibrosis (2016) (0)
- Mo1951 - Chemoprophylaxis of Azoxymethane/DSS-Induced Colonic Carcinogenesis in C57Bl/6 Mice using a Combination Therapy with Rapamycin and a Probiotic (2018) (0)
- IDDF2019-ABS-0102 Comparison of murine steatohepatitis models identifies a dietary intervention with robust fibrosis, ductular reaction and rapid progression to cirrhosis, cancer (2019) (0)
- P629 LONG-ACTING GLUCAGON-LIKE PEPTIDE-1 RECEPTOR AGONISM MITIGATES INFLAMMATION AND FIBROSIS IN MODELS OF NASH AND BILIARY FIBROSIS (2014) (0)
- Dietary supplementation with conjugated linoleic acid influences central nervous system autoimmunity via the gut-central nervous system axis (2018) (0)
- P0455 : IL-4Ra oegulates liver fibrosis differently during progression and reversal phases by modulating the ratio of M1 vs M2 macrophages (2015) (0)
- THE 5A/5A GENETIC POLYMORPHISMS OF MATRIXMETALLO-PROTEINASE-3 IS ASSOCIATED WITH THE PROGRESSION TO CIRRHOSIS IN ALCOHOLIC LIVER DISEASE. (2004) (0)
- Method for diagnosis of inflammatory bowel disease (2001) (0)
- Novel Insight into Pulmonary Fibrosis and Long Covid. (2023) (0)
- Blocking IL-1 signaling in hepatocytes undergoing metabolic stress protects against metabolic inflammation and attenuates pro-coagulant factors (2020) (0)
- Single cell RNA-seq of patient liver tissues uncover HRH2+/CLEC5a high/macro low macrophages as therapeutic target for the treatment of liver fibrosis and cancer prevention (2020) (0)
- Is there a murine model that fully recapitulates human NASH? An unbiased bioinformatics approach to rank pre-clinical models based on proximity to human disease (2022) (0)
- 323 Beta 3 specific non-peptidic integrin antagonist EMD409915 inhibits hepatic stellate cells migration via P38 and FAK signalling pathways (2004) (0)
- Reply to Comment on Huang, X., et al. “Sourdough Fermentation Degrades Wheat Alpha-Amylase/Trypsin Inhibitor (ATI) and Reduces Pro-Inflammatory Activity”. Foods 2020, 9, 943 (2020) (0)
- Tissue transglutaminase antibodies in patients with confirmed food allergy (2001) (0)
- Mo1989 – Assessment of Novel Candidate Biomarkers of Celiac Disease Activity (2019) (0)
- Native extraction of phosphotyrosine-containing proteins: requirement of tyrosine kinase inhibitors to obtain specific phosphorylation signals. (2000) (0)
- Inhibitionof IL-1 signaling in hepatocytes retains insulin sensitivity and protects fromhepatocellular injury in nonalcoholic fatty liver disease (2018) (0)
- Additive anti-Tumor Response to the Rabbit VX2 Hepatoma by Combined Radio Frequency Ablation and Toll like Receptor 9 Stimulation (2014) (0)
- In vivo cell specific gene silencing in the liver using novel siRNA-loaded biodegradable nanohydrogel particles (2016) (0)
- OL-048 Identification of Helicobacter hepaticus and Helicobacter species in liver samples from Egyptian patients with hepatitis C cirrhosis with or without hepatocellular carcinoma (2008) (0)
- Combination of biomodulators induce apoptosis probably mediated via mitochondria (2003) (0)
- Quantitative tests of liver function reveal compromised liver function in patients with alcoholic VS. non-alcoholic cirrhosis matched for child pugh grade (2000) (0)
- Radioimmunoassay fortheCarboxy-terminal Cross-linking DomainofTypeIV (Basement Membrane)Procollagen inBodyFluids Characterization andApplication toCollagen TypeIVMetabolism inFibrotic Liver Disease (1986) (0)
- Modern concepts of coeliac disease pathogenesis (2006) (0)
- Anti-tumoral efficiacy of four different histone deacetylase inhibitors on hepatoma cells in vitro (2003) (0)
- HIV AND HCV INCREASE HEPATIC FIBROSIS PROGRESSION IN HEPATIC STELLATE CELLS AND HEPATOMA CELLS VIA ROS AND NF kappa B INDUCTION (2010) (0)
- Abstract 154: Endothelial Dysfunction In Experimental Celiac Disease Is Mediated By Gut-Derived Vascular Inflammation And Oxidative Stress (2022) (0)
- Differential expression of c-jun and c-myc protooncogenes during gastric ulcer development (1998) (0)
- S2034 Wnt11 Production in Celiac Disease is Triggered by Stimulation of Innate Immunity and Subsequent Il15 Release (2010) (0)
- S1595 Rapid Predictive Mouse Model of Parenchymal Liver Fibrosis for Antifibrotic Drug Screening In Vivo (2009) (0)
- Liver/intestinal collagens type I, III and VI bind keratinocyte growth factor (KGF/FGF-7) via the collagenous binding motives (GPO) X and (GPP) X (2002) (0)
- C-myc and c-H-ras RNA expression in rat liver following intoxication with CC14 (1989) (0)
- Simultaneous m measurement o of c collagen ttype-VI-related antigen a and p procollagen ttype-III-N-propeptide levels iin b bronchoalveolar llavage (1994) (0)
- Tu1862 - Nutritional Wheat Alpha-Amylase/Trypsin Inhibitors Enhance Intestinal Inflammatory Monocytes and Aggravate Colonic Inflammation in DSS-Induced Colitis (2018) (0)
- Osteoprotegerin expression in liver is induced by IL-13 through TGF-β (2020) (0)
- Diagnosis of liver fibrosis with the help of serum marker algorithms (2001) (0)
- Representation of human non-alcoholic fatty liver disease in murine models (2015) (0)
- Undulin gene expression in normal and fibrotic human liver (1991) (0)
- Synthetic collagen-oligopeptides inhibit binding of platelet derived growth factor BB to the hepatic extracellular matrix (2001) (0)
- 340 GPO10, a collagen mimetic effectively promotes activation of collagen-bound pro-matrix-metalloproteinase-2 in fibrotic liver tissue (2006) (0)
- Serum laminin-2 and hyaluronan predict advanced liver fibrosis in children with chronic hepatitis B (2002) (0)
- Glucagon-like peptide-1 receptor agonists ameliorate inflammation and fibrosis in an optimized rodent NASH model via inhibition of inflammatory macrophage activation (2017) (0)
- Small Bowel: From Sideline to Center Stage in Gastroenterology (2015) (0)
- [Overexpression of B7-1 amd B7-2 by LFA-1 positive lymphocytes in chronic inflammatory bowel diseases]. (1998) (0)
- A diet containing wheat alpha-amylase/trypsin inhibitors (ATIs) promotes allergic airway inflammation in mice. (2014) (0)
- Macrophages induce a divergent fibrotic response, in human lung fibroblasts, compared to TGF-β alone (2017) (0)
- Peptide-based carrier devices for stellate cells and other cell-types involved in chronic inflammatory and fibrotic disorders (2004) (0)
- 1252 Homozygosity for the alcoholdehydrogenase 3*1 allele is associated with hepatocellular carcinoma in alcohol-induced cirrhosis (2003) (0)
- Immunoelectron microscopic localization of undulin and fibronectin in the human periodontal ligament and cementum (1996) (0)
- Effect of Nutritional Wheat Amylase Trypsin Inhibitors on the Progression of Non-Alcoholic Fatty Liver Disease (2016) (0)
- Measurement of TIMP-1 in serum by the bayer immuno 1® mirrors hepatic fibrogenesis (1998) (0)
- Liver metastases and procollagen mRNAs expression (1990) (0)
- Subject Index, Vol. 68, 1995 (1995) (0)
- [Pathomorphology of acute and chronic stages of CCl4-induced liver fibrosis: immunohistochemical and in situ hybridization studies]. (1992) (0)
- Dual-agent molecular targeting of growth factor receptors in hepatocellular cancer: Combining anti-EGFR antibody with an EGFR tyrosine kinase inhibitor (2005) (0)
- Evaluation of Laboratory and Sonographic Parameters for Detection of Portal Hypertension in Patients with Common Variable Immunodeficiency (2022) (0)
- Silymarin increases retinyl ester concentration in rats with secondary biliary cirrhosis (1998) (0)
- Motilin-Related Peptide and Ghrelin: Lessons From Molecular Techniques, Peptide Chemistry, and Receptor Biology (2001) (0)
- THU-469-Nanoparticular bisphosphonate to selectively target and repolarize liver macrophages for efficient anti-tumour response (2019) (0)
- 513 HLA-DR*405 Transgenic NOD Mice Develop Autoimmune Pancreatitis (2008) (0)
- [Significance of epithelial-mesenchyme interactions in microvascular pedicled small intestine transplants replacing oral mucosa]. (1990) (0)
- Sa1990 Cereal Alpha-Amylase/Trypsin Inhibitors (ATIs) As Nutritionals Triggers of Innate Immunity: Bioactivity in Various Foods (2014) (0)
- [336] THE ANTIFIBROTIC EFFECT OF MYCOPHENOLATE MOFETIL IS LOST AT CLINICALLY RELEVANT DOSE, FOLLOWING A BIPHASIC DOSE-DEPENDENT PATTERN IN LIVER FIBROSIS (2007) (0)
- 907 Early drivers of dermal fibrosis: Central role of CD11b+ myeloid cells (2018) (0)
- P0419 : In vivo cell specific gene silencing in the liver using novel siRNA-loaded nanohydrogel particles (2015) (0)
- Functional inhibition of Oct leads to HNF4α upregulation (2021) (0)
- Mo1823 Dietary Wheat Alpha-Amylase-Trypsin Inhibitors (ATIS) Worsen Intestinal Inflammation in Mice (2015) (0)
- 946 – A High Rate of Ige-Negative Food Allergies in Patients with Irritable Bowel Syndrome (2019) (0)
- Comparison of quantitative liver function tests and common prognostic scores in patients with primary biliary cirrhosis (2002) (0)
- An extracellular proteasome releases endostatin from human collagen XVIII (2016) (0)
- Beta 3-specific non-peptidic integrin inhibitor EMD409915 blocks PDGF-BB stimulated migration in HSC via inhibition of p38 signalling pathway (2004) (0)
- Ablation of Interleukin-4 Receptor alpha in macrophages ameliorated steatohepatitis and fibrosis in murine model of non alcoholic steatohepatitis (NASH) (2018) (0)
- 1004 Celiac Disease Model in Rag1-/- Mice Adoptively Transferred with Gliadin-Sensitized Effector/Memory T Cells, Challenged with Oral Gluten (2008) (0)
- Specific endothelin a receptor antagonism retards fibrogenesis in ratbiliary fibrosis (2000) (0)
- Tissue transglutaminase-specific HLA-DQ2 restricted T cell clones from peripheral blood of patients with coeliac disease (2006) (0)
- 364 MODULATION OF LIVER FIBROSIS BY REGULATING ALTERNATIVELY ACTIVATED MACROPHAGE SIGNALING THROUGH IL-4Ralpha (2013) (0)
- 1120 EFFECT OF MATRIX METALLOPROTEINASE-8 DEFICIENCY ON LIVER FIBROSIS PROGRESSION AND REGRESSION (2013) (0)
- 165 T-Cell Derived Microparticles Induce Fibrolytic Activation of Hepatic Stellate Cells via ICAM-1 (CD54) Dependent Uptake and Emmprin (CD147) (2010) (0)
- Hepatocyte growth factor (HGF) and proinflammatory cytokines induce gastrin in hepatic cells: An important link in the development of hepatocellular carcinoma (HCC)? (2003) (0)
- Fibrosis in Hodgkin's disease: fibrogenesis, fibrolysis, and factors contributing to their regulation (1995) (0)
- 1289 Fragments of the liver collagens VI and XIV show distinct effects on differentiation of adipocytes and hepatic stellate cells (2003) (0)
- Measurement of Reactive Oxygen and Nitrogen Species in Living Cells Using the Probe 2',7'-Dichlorodihydrofluorescein. (2021) (0)
- [205] INHIBITION OF ANGIOGENESIS IN VIVO BY ALPHA(V)BETA(3) INTEGRIN ANTAGONIST EMD121974 AGGRAVATES BILIARY FIBROSIS IN RATS (2007) (0)
- [482] HEPATIC EXPRESSION OF GLUTATHIONE-S-TRANSFERASE P1 IS MARKEDLY UPREGULATED IN CHRONIC HEPATITIS C AND CORRELATES WITH FIBROSIS (2007) (0)
- Nutritional α-amylase/trypsin inhibitors (ATIs) promote macrophage infiltration into liver associated with increased expression of the endocannabinoid 1 receptor (eCBr-1) (2014) (0)
- 247 Combined tamoxifen and 9CIS retinoic acid show a high efficacy in a syngenic rat model or HCC (2004) (0)
- Optimierung inhibitorischer Peptide der MMP-2/-9– Kollagen Interaktion mittels Surface Plasmon Resonance (2015) (0)
- Mo1050 - IBS Patients with Reaction to Wheat and Other Food Antigens Proven on Confocal Laser Endomicroscopy (CLE) have Prognostic Parameters for Disease, Irrespective of the Antigen They React to (2018) (0)
- AN EARLY TARGET OF PRESERVATION/REPERFUSION INJURY AND ACUTE REJECTION AFTER SMALL BOWEL TRANSPLANTATION 1 (1998) (0)
- Hepatic Toxicity Induced by Herbal Medicines (2008) (0)
- Effectivity of a combination of the anti-estrogen tamoxifen and 9cis-retinoic acid on hepatocellular in vivo (2003) (0)
- Interleukin-1β and tumor necrosis factor-α enhance human intestinal fibroblast-dependent growth of human intestinal mast cell (2003) (0)
- 84 IN VIVO INHIBITION OF HEPATIC FIBROSIS BY C12-200-LIPOSOMES CARRYING ANTIFIBROTIC SIRNAS (2012) (0)
- 1 Identification of Food-grade Subtilisins as Gluten-degrading Enzymes to Treat Celiac Disease 1 2 (2016) (0)
- 495 - Search for and Identification of Serum Markers of Celiac Disease Activity (2018) (0)
- Upregulation of collagen XVIII rna expression in colorectal carcinomas and colorectal liver metastases (1998) (0)
- Title Page / Contents / Imprint / Guidelines (2014) (0)
- FRI-281-IL-4 receptor alpha knock-out mice are protected against fibrotic NASH in a representative mouse model of non-alcoholic steatohepatitis (2019) (0)
- A266 AMYLASE TRYPSIN INHIBITORS FROM WHEAT EXACERBATE GLUTEN-INDUCED PATHOLOGY AND ALTER GUT MICROBIOTA IN MICE (2018) (0)
- Influence of faecal contents from a gluten-free vs. gluten-containing diet on α-amylase/trypsin inhibitor-mediated inflammation (2012) (0)
- Activation of tumor specific T-lymphocytes caused by radio frequency ablation of liver tumors — A patient study (2003) (0)
- 31 MONOCYTE/MACROPHAGE PERIBILIARY RECRUITMENT BY PKHD1-DEFECTIVE CHOLANGIOCYTES INDUCES EXPRESSION OF αvβ6 INTEGRIN ON BILIARY CYSTS VIA TGF-β1 AND TNF-α IN CONGENITAL HEPATIC FIBROSIS (2012) (0)
- TLR4 Signaling Differentially Affects Progenitor Cell Subset Expansion and Activation during Liver Injury (2016) (0)
- A method for detecting antibodies from body fluids by an immune reaction with tissue transglutaminase (tTG), as well as the use of tTG in diagnosis and therapy (1996) (0)
- A FUNCTIONAL POLYMORPHISM IN THE MANGANESE-SUPEROXIDE-DISMUTASE GENE IS ASSOCIATED WITH THE DEVELOPMENT OF CHRONIC ALCOHOLIC PANCREATITIS. (2004) (0)
- Methods for diagnosis of chronic inflammatory bowel disease (2002) (0)
- Tu1815 Mice Fed a High-Fat High-Fructose Diet and Treated With Low Dose Streptozotocin Develop Insulin Resistance, NASH and Liver Fibrosis (2012) (0)
- Mice on a high-fat, high-fructose diet and treated with low dose streptozotocin develop features of human NASH (2012) (0)
- Liver fibrosis progression and regression in matrix metalloproteinase-8 deficient mice (2013) (0)
- 289 - Food Intolerance in IBS is due to an Eosinophil Acrivation Synrdome? (2018) (0)
- Rapamycin and Zoledronic Acid strongly inhibit growth of advanced murine hepatocellular carcinoma via activation of innate and adaptive immunity (2018) (0)
- FRI-452-Synergistic reduction of cancer proliferation and tumour growth in advanced murine hepatocellular carcinoma vis skewing and activation of innate and adoptive immunity (2019) (0)
- 655 SERUM MICROPARTICLES (MP) AS A NOVEL TOOL TO IDENTIFY HEPATOCELLULAR CARCINOMA (HCC) (2013) (0)
- Microparticles Are Novel Biomarkers in Predicting Celiac Disease Activity: 324 (2012) (0)
- 245 THE ORAL TISSUE TRANSGLUTAMINASE INHIBITOR ZED1227 PREVENTS GLUTEN-INDUCED ENTEROPATHY IN A TRANSGENIC MOUSE MODEL OF CELIAC DISEASE (2021) (0)
- 1000 Gliadin Elicits An Innate Immune Response in Monocytic and Intestinal Epithelial Cells Via the MyD88 Pathway (2008) (0)
- Synergistic inhibition of hepatoma cell proliferation with a combination of 9-CIS-retinoid acid, tamoxifene and the angiogenesis inhibitor TNP (2000) (0)
- Keratinocyte growth factor binds to collagens of the gastrointestinal tract: Identification of the collagen binding structure (2001) (0)
- 1254 Effectivity of a combination of the anti-estrogen tamoxifen and 9cis-retinoic acid in rat HCC model (2003) (0)
- THU-104-New fibroblast activation protein inhibitor, CPD, attenuates fibrosis and chronic liver disease progresion in CCL4 induced liver fibrosis, but not in MDR2-/- mice (2019) (0)
- Identification of novel anti-inflammatory herbal extracts (2017) (0)
- 533 Mouse Strain Differences in Macrophage-Mediated Clearance of Dead Hepatocytes Accounts for Differences in Susceptibility to Liver Fibrosis (2009) (0)
- [The distribution of the basal membrane constituents of collagen type IV and laminin in oral squamous cell carcinomas]. (1986) (0)
- The antifibrotic effect of pentoxifylline in rat secondary biliary fibrosis is paralleled by an increase of hepatic retinyl esters (1998) (0)
- Tissue transglutaminase (tTG)-specific T cell clones from peripheral blood of coeliac patients (2004) (0)
- Herbal hepatotoxicity – reply (2006) (0)
- Endoscopic Pancreatic Necrosectomy in 28 Patients By EUS-Guided NOTES®: Improved Method with Reduced Number of Procedures and Low Complication Rates (2009) (0)
- Su1087 A GUT-TARGETED EICOSAPENTAENOIC ACID DERIVATIVE, SEFA-1024, AMELIORATES DEXTRAN SODIUM SULFATE (DSS)-INDUCED INTESTINAL INFLAMMATION (2020) (0)
- Lecture ‒ Antifibrotic Therapy: Future Cure for Portal Hypertension? (2008) (0)
- The insulin-like growth factor receptor is a promising target for innovative treatment approaches of hepatocellular cancer (2005) (0)
- [Clinical, morphologic and immunohistochemical studies of oral Kaposi sarcoma (AIDS)]. (1988) (0)
- IL-4RA Signaling Regulates Liver Fibrosis Progression and Reversal Differently by Modulating Polarization of M2 Macrophage Subsets (2016) (0)
- Correlation of hepatic matrix gene expression in diagnostic biopsies with surrogate serum markers of fibrogenesis and fibrolysis (2001) (0)
- Alpha-Amylase/Trypsin Inhibitors, novel activators of innate immunity in ex-vivo tissue explants (2013) (0)
- New Combinatory Treatment on a Rat HCC Model (2005) (0)
- Vergleich der anti-tumoralen Effektivität verschiedener Histondeazetylasehemmer an Hepatomzellen in vitro (2015) (0)
- Abstracts des 32. Mainzer Allergie-Workshops, 20./21. März 2020 (2020) (0)
- Der Genotyp 5A/5A der Matrixmetalloproteinase–3 ist mit der alkoholischen Leberzirrhose assoziiert (2004) (0)
- Fallbericht eines Sprue-Patienten mit kapselendoskopisch ausgeprägter Zottenatrophie im gesamten Dünndarm (2004) (0)
- Der Genotyp 5a/5a eines funktionellen Polymorphismus der Matrixmetalloproteinase-3 (Stromelysin)– ist mit der Alkohol-induzierten Leber-Zirrhose assoziiert (2004) (0)
- Der funktionelle MMP-3 (-1171; 5A/6A) Polymorphismus ist kein Risikofaktor für die Entwicklung einer Alkohol-induzierten Leberzirrhose (2006) (0)
- Inhibition der PDGF-stimulierten Migration von hepatischen Sternzellen durch einen nicht-peptidischen β3 Integrin Antagonisten (2015) (0)
- Weizen, Gluten, ATI: eine Einführung (2018) (0)
- Präklinische Evaluation Dextran-basierter Nanopartikel für die Leber- und Makrophagen-spezifische Pharmakotherapie (2015) (0)
- Alpha v Beta 6 Integrin ist in der experimentellen Leberfibrose und bei chronischer Hepatitis C dramatisch hochreguliert (2006) (0)
- Kollagen Typ VI und seine alpha2-Kette fördern die Leberfibrose durch Inhibition der Kollagenaseaktivität (2006) (0)
- Purifikation, Charakterisierung und biologische Wirkungen von alpha-Amylase-/Trypsininhibitoren aus Pflanzen, Effektoren von intestinalen TLR4 bei Zöliakie (2012) (0)
- Die Bindung von Kollagen VI an hepatische Sternzellen koaktiviert den Plättchenwachstumsfaktor-Rezeptor alpha (PDGFR-a) (2015) (0)
- Getreidebedingte Unverträglichkeiten: Einführung in die Immunologie des Darms (2018) (0)
- Radiofrequenzablation solider Lebertumore verursacht eine dramtisch gesteigerte zytolytische Aktivität von T-Lymphozyten (2005) (0)
- Isolierte Erhöhung der γGT: Was ist diagnostisch erforderlich? (2004) (0)
- Nicht immer ist es Weizen (2018) (0)
- Fra-2 transgene Mäuse entwickeln einen Phänotyp der primären sklerosierenden Cholangitis (2018) (0)
- Zeitlicher Verlauf der Verteilung von Theophyllin zwischen Erythrozyten und Plasma bei gesunden Erwachsenen (1982) (0)
- Gibt es prognostische Parameter bei endomikroskopisch und diätetischer gesicherter Nahrungsmittelsensitivität (NMS)? Untersuchungen an Reizdarmpatienten mit mittels konfokaler Endomikroskopie (EM) gesicherter Nahrungsmittelintoleranz und deutlicher Besserung unter 3-monatiger Auslassdiät (2017) (0)
- Bedeutung des Organischen Kationentransporters OCT1 im Diethylnitrosamin und Phenobarbital Tumormodell in OCT3-Knockout Mäusen (2015) (0)
- Nachweis von Autoantikörpern gegen Gewebstransglutaminase bei Patienten mit Dermatitis herpetiformis Duhring, nicht aber bei linearer IgA-Dermatose (2000) (0)
- Aktivierte hepatische Sternzellen exprimieren Ca2+-aktivierte K+-Kanäle– spezifischer Blocker hemmen signifikant die Proliferation (2004) (0)
- Überexpression von B7-1 und B7-2 auf LFA-1 positiven Lymphozyten bei chronisch entzündlichen Darmerkrankungen (1998) (0)
- Ernährung und chronisch entzündliche Erkrankungen (2021) (0)
- Signifikante Beeinflußung des hyperthermischen Effektes durch Stärkemikrospheren (Spherex ® ) bei der Laser-induzierten Thermotherapie im Lebermetastasenmodell der Ratte (1998) (0)
- Leberzirrhose bei NASH – eine unterschätzte Komplikation? (2017) (0)
- Vorhersagbarkeit des Therapieansprechens auf PEG-Interferon alfa–2a/Ribavirin bei Patienten mit chronischer Hepatitis C vom Genotyp 1, 2 und 3 (2007) (0)
- Aktivierung tumorspezifischer T-Lymphozyten durch Hochfrequenzinduzierte Thermotherapie inoperabler menschlicher Lebertumore (2004) (0)
- Die Rolle von Polymorphismen der Mangan-Superoxid-Dismutase und Glutathion-S-Transferase P1 in der Fibroseprogression bei chronischer Hepatitis C (2004) (0)
- Die Bindegewebsmarker MMP-2 und TIMP-1 sind unabhängige prognostische Faktoren für das tumorspezifische Überleben bei Patienten mit metastasiertem kolorektalem Karzinom unter einer palliativen Erstbehandlung (2015) (0)
- Immunhistochemisch/PCR positive Permeabilitätserhöhung der duodenalen Tight Junctions bei Patienten mit Reizdarmsyndrom (IBS) und Weizen-Sensitivität, nachgewiesen in konfokaler Laser-Endomikroskopie (CLE) (2017) (0)
- Die Rolle eines funktionellen Polymorphismus in der Signalsequenz des TGF β 1-Gens bei der Entwicklung der Alkohol-Induzierten Leberzirrhose (2004) (0)
- Das Immunom des hepatozellulären Karzinoms ist mit dem Überleben assoziiert (2017) (0)
- Die Rolle funktioneller Polymorphismen der Mangan-Superoxide-Dismutase bei der Entstehung der alkoholbedingten chronischen Pankreatitis (2004) (0)
- Wöchentliche Hochdosisbehandlung mit 5-FU/Folinsäure (FA) als 24-Stunden-Infusion (AIO) plus Irinotecan (IRI) in der Zweit- und Drittbehandlung des kolorektalen Karzinoms (CRC) bei mit Oxaliplatin (L-OHP) vorbehandelten Patienten (2015) (0)
- Gliadin induziert angeborene Immunreaktionen in monozytären und epithelialen Zellen über den MyD88-Signaltransduktionsweg (2008) (0)
- [204] THE PHARMACOLOGICAL INHIBITION OF ALPHA(V)BETA(6) INTEGRIN ALLEVIATES SECONDARY BILIARY FIBROSIS IN RATS VIA INHIBITION OF TGF-BETA ACTIVATION AND CHOLANGIOCYTE ADHESION TO FIBRONECTIN (2007) (0)
- Erkrankungen des Magen-Darm-Traktes (2003) (0)
- Der Matrixmetalloproteinasen Inhibitor Actinonin hemmt die Tumorzellinvasion von CC531-Zellen ex vivo und reduziert die hepatische Metastasierung am Lebermetastasenmodell der Ratte in vivo (2004) (0)
- Überadditiver Effekt einer Kombination aus Tamoxifen und einem Retinoid in der Therapie des HCC in vitro (2015) (0)
- Weizen und Gluten: Die Ursache vielen Übels? (2020) (0)
- Der Genotyp 105VAL/VAL des Glutathion-S-Transferase P1 Gens determiniert die Progression zur Zirrhose bei Patienten mit Hereditärer Hämochromatose (2004) (0)
- Erwiderung auf den Leserbrief zum Beitrag „Neue Therapieoption für akute hepatische Porphyrien“ (2021) (0)
- Laminin und Hyaluronsäure als Indikatoren für die initiale Transplantatfunktion sowie für die akute Abstoßung nach Dünndarmtransplantation (1997) (0)
- Autoantikörper von Sprue-Patienten hemmen die enzymatische Aktivität der Transglutaminase nur partiell (2015) (0)
- Der ADH3*1/1-Genotyp ist mit alkoholinduzierten Karzinomen des oberen Gastrointestinaltraktes und dem hepatozellulären Karzinom assoziiert (2015) (0)
- Balb/c und C57/Bl6 Mäuse unterscheiden sich in ihrer Anfälligkeit und Immunantwort auf Lebermetastasen des B16F10 Melanoms (2015) (0)
- Innovative Versorgungsform: unsere Sprechstunde für nahrungsmittelbedingte Erkrankungen (2018) (0)
- Auswirkungen der Pfortaderarterialisation auf Funktion, Regeneration und Morphologie nach Hemihepatektomie beim Schwein (2002) (0)
- So erkennen Sie entzündliche Weizensensitivitäten (2020) (0)
- Nouvelle association pharmaceutique (2003) (0)
- Introduction (2019) (0)
- Mutationsspezifische K-ras-siRNAs hemmen das Wachstum humaner Pankeaskarzinomzellen in vitro (2015) (0)
- Outlook (2019) (0)
- Vermindertes Wachstum residualen Tumorgewebes nach In-situ Ablation experimenteller Lebermetastasen im Vergleich zur chirurgischen Resektion ist mit erhöhter mRNA-Expression von Connective Tissue Growth Factor (CTGF) assoziiert (2001) (0)
- Untersuchung der profibrogenen Eigenschaften von Fragmenten der extrazellulären Matrix: Kollagen VI-Fragment–freigesetzt aus der zirrhotischen Leber–aktiviert hepatische Sternzellen und bewirkt eine Hochregulierung der Kollagen I- und TIMP–1-Synthese und eine Herunterregulierung von MMP–3/–13 (2005) (0)
- Laktose-, Fruktose- und Histamin-Intoleranz: überdiagnostiziert und von Patienten überbewertet (2018) (0)
- Weizen Amylase/Trypsin-Inhibitoren verstärken die experimentelle eosinophile Ösophagitis (2018) (0)
- German Celiac Registry (GeCeR) - Untersuchung der Lebensqualität und psychosozialen Belastung bei Zöliakie (2020) (0)
- Mycophenolat Mofetil vermindert die Prokollagenα1(I) and TGFβmRNS Expression hepatischer Sternzellen (2015) (0)
- Medikament zur behandlung einer fibrotischen erkrankung durch rna interferenz (2002) (0)
- Foreword (2019) (0)
- Halofuginon inhibiert in vitro die Migration und Proliferation von aktivierten hepatischen Sternzellen durch Aktivierung der Proteinkinase p38 (2015) (0)
- Randomisierte, geblindete Cross-Over-Studie zu konfokaler Endomikroskopie (EM) und Differenzierung von Weizen und Gluten-Sensitivität (NCGS) bei Patienten mit Reizdarmsyndrom (IBS): Antigen Ausschlussdiät vs. Sham vs. low FODMAP-Diät zur Evaluierung einer erfolgreichen Diagnostik (2017) (0)
- Weizen Amylase/Trypsin-Inhibitoren verstärken IgE-abhängige Nahrungsmittelallergien (2018) (0)
- Die Expression des Rezeptors für Advanced Glycation End Products auf hepatischen Sternzellen wird durch AGEs, TNF-alpha und Aktivierung stimuliert (2004) (0)
- Der Histondeacetylasehemmer SAHA potenziert die pro-apoptotische Wirkung von 5-Fluoruracil und Irinotecan für hepatozelluläre Karzinomzellen in vitro (2015) (0)
- Rolle des HIF1-PHD Feedback Loops in der Leber: HIF1 ist kein absoluter Sauerstoffsensor sondern eine Stoffwechselkontrolle (2008) (0)
- Autoren (2021) (0)
- Klassische und atypische Nahrungsmittelallergien (2018) (0)
- Alkohol-Assoziierte polare Retinoidmetabolite induzieren Apoptose in Leberzellen durch Schädigung des mitochondrialen Membranpotenzials (2004) (0)
- Ergebnisse zur Inhibition von EGF- und IGF-1 Rezeptoren bei hepatozellulären Karzinomen (2006) (0)
- Einfluss des DNA-Methyltransferase-Inhibitors Zebularin und des Histondeazetylase-Inhibitors SAHA auf Apoptose, Promotormethylierung und Differenzierung humaner Pankreaskarzinomzellen in vitro (2004) (0)
- Pharmazeutische Zusammensetzungen enthaltend cis-Retine Säure (2003) (0)
- GEWEBSTRANSGLUTAMINASE ALS AUTOANTIGEN BEI DER EINHEIMISCHEN SPRUE: NEUE ASPEKTE IN DIAGNOSTIK UND ATIOPATHOGENESE (2008) (0)
- Adhesion of human intestinal mast cells (MC) to extracellular matrix proteins (1998) (0)
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