Diane Barber
#122,289
Most Influential Person Now
American cell physiologist and biologist
Diane Barber's AcademicInfluence.com Rankings
Diane Barberbiology Degrees
Biology
#8639
World Rank
#11746
Historical Rank
#2352
USA Rank
Physiology
#486
World Rank
#727
Historical Rank
#60
USA Rank
Cell Biology
#770
World Rank
#787
Historical Rank
#77
USA Rank
Molecular Biology
#2480
World Rank
#2519
Historical Rank
#265
USA Rank
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Biology
Diane Barber's Degrees
- PhD Cell Biology University of California, Berkeley
- Bachelors Biology Stanford University
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Why Is Diane Barber Influential?
(Suggest an Edit or Addition)According to Wikipedia, Diane L. Barber is an American cell biologist. She is an Endowed Professor and Chair of the Department of Cell and Tissue Biology at University of California, San Francisco and an elected American Association for the Advancement of Science fellow in recognition of her "distinguished contributions on cell signaling by plasma membrane ion transport proteins and on the design and function of proteins regulated by intracellular pH dynamics." In addition to teaching graduate and professional students and her administrative service, she directs a research laboratory funded by grants from the National Institutes of Health and the National Science Foundation .
Diane Barber's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Dysregulated pH: a perfect storm for cancer progression (2011) (1500)
- Dissecting the tumor myeloid compartment reveals rare activating antigen-presenting cells critical for T cell immunity. (2014) (525)
- The changing face of the Na+/H+ exchanger, NHE1: structure, regulation, and cellular actions. (2002) (477)
- Dissecting the Tumor Myeloid Compartment Reveals Rare Activating Antigen-Presenting Cells Critical for T Cell Immunity. (2014) (456)
- Direct binding of the Na--H exchanger NHE1 to ERM proteins regulates the cortical cytoskeleton and cell shape independently of H(+) translocation. (2000) (407)
- Cell migration requires both ion translocation and cytoskeletal anchoring by the Na-H exchanger NHE1 (2002) (390)
- Molecular Analysis of System N Suggests Novel Physiological Roles in Nitrogen Metabolism and Synaptic Transmission (1999) (316)
- Na-H Exchange-dependent Increase in Intracellular pH Times G2/M Entry and Transition* (2003) (242)
- Intracellular pH sensors: design principles and functional significance. (2007) (229)
- p160ROCK mediates RhoA activation of Na–H exchange (1998) (218)
- A Human MAP Kinase Interactome (2010) (212)
- Cancer cell behaviors mediated by dysregulated pH dynamics at a glance (2017) (208)
- Dynamic actin remodeling during epithelial–mesenchymal transition depends on increased moesin expression (2011) (206)
- Na-H exchange acts downstream of RhoA to regulate integrin-induced cell adhesion and spreading. (1998) (203)
- Cofilin is a pH sensor for actin free barbed end formation: role of phosphoinositide binding (2008) (182)
- G13 Stimulates Na-H Exchange through Distinct Cdc42-dependent and RhoA-dependent Pathways (*) (1996) (177)
- Cloning and sequence analysis of cDNA for the canine neurotensin/neuromedin N precursor. (1987) (171)
- G alpha 13 stimulates Na-H exchange. (1994) (168)
- Na(+)/H(+) exchanger NHE1 as plasma membrane scaffold in the assembly of signaling complexes. (2004) (164)
- Ion transport proteins anchor and regulate the cytoskeleton. (2002) (156)
- A calcineurin homologous protein inhibits GTPase-stimulated Na-H exchange. (1996) (151)
- The Nck-interacting kinase phosphorylates ERM proteins for formation of lamellipodium by growth factors (2006) (141)
- Considering protonation as a posttranslational modification regulating protein structure and function. (2013) (125)
- Inhibition of Calcineurin Phosphatase Activity by a Calcineurin B Homologous Protein* (1999) (119)
- Structural model and functional significance of pH-dependent talin–actin binding for focal adhesion remodeling (2008) (113)
- The Nck-interacting Kinase (NIK) Phosphorylates the Na+-H+ Exchanger NHE1 and Regulates NHE1 Activation by Platelet-derived Growth Factor* (2001) (107)
- Positive feedback between Cdc42 activity and H+ efflux by the Na-H exchanger NHE1 for polarity of migrating cells (2007) (105)
- Structures of human phosphofructokinase-1 and atomic basis of cancer-associated mutations (2015) (98)
- The Sodium-Hydrogen Exchanger NHE1 Is an Akt Substrate Necessary for Actin Filament Reorganization by Growth Factors* (2009) (97)
- Beyond ion translocation: structural functions of the sodium–hydrogen exchanger isoform-1 (2007) (88)
- Phosphorylation of the Arp2/3 complex is necessary to nucleate actin filaments (2008) (83)
- Expression profile of genes regulated by activity of the Na-H exchanger NHE1 (2004) (81)
- Beta-adrenergic and somatostatin receptors regulate Na-H exchange independent of cAMP. (1989) (80)
- Gα12 Differentially Regulates Na+-H+ Exchanger Isoforms* (1996) (78)
- pH sensing by FAK-His58 regulates focal adhesion remodeling (2013) (76)
- Activation of Na+-H+ Exchange Is Necessary for RhoA-induced Stress Fiber Formation* (1996) (73)
- Subtype-specific signaling mechanisms of somatostatin receptors SSTR1 and SSTR2. (1994) (72)
- A developmentally regulated Na-H exchanger in Dictyostelium discoideum is necessary for cell polarity during chemotaxis (2005) (70)
- Increased H+ efflux is sufficient to induce dysplasia and necessary for viability with oncogene expression (2015) (69)
- Multiple receptors coupled to adenylate cyclase regulate Na-H exchange independent of cAMP. (1990) (69)
- Cell fate decisions: emerging roles for metabolic signals and cell morphology (2017) (67)
- A dominant negative erythropoietin (EPO) receptor inhibits EPO-dependent growth and blocks F-gp55-dependent transformation (1994) (62)
- Increased intracellular pH is necessary for adult epithelial and embryonic stem cell differentiation (2016) (61)
- The glycolytic enzyme phosphofructokinase-1 assembles into filaments (2017) (58)
- Somatostatin, Acting at Receptor Subtype 1, Inhibits Rho Activity, the Assembly of Actin Stress Fibers, and Cell Migration* (2002) (52)
- A common epitope is shared by activated signal transducer and activator of transcription-5 (STAT5) and the phosphorylated erythropoietin receptor: implications for the docking model of STAT activation. (2001) (47)
- Electrostatics Control Actin Filament Nucleation and Elongation Kinetics* (2013) (45)
- Cancer-associated arginine-to-histidine mutations confer a gain in pH sensing to mutant proteins (2017) (43)
- Morphologic and physiologic studies of canine ileal enteroglucagon-containing cells in short-term culture. (1987) (42)
- Ratiometric imaging of pH probes. (2014) (40)
- The Nck-interacting kinase NIK increases Arp2/3 complex activity by phosphorylating the Arp2 subunit (2015) (40)
- Guanine nucleotides regulate beta-adrenergic activation of Na-H exchange independently of receptor coupling to Gs. (1992) (37)
- Release and characterization of cholecystokinin from isolated canine jejunal cells. (1986) (36)
- The morphology, development and physiology of blood cells (1982) (33)
- Studies on the origin of the hydroxyl spin adduct of DMPO produced from the stimulation of neutrophils by phorbol-12-myristate-13-acetate. (1987) (33)
- G alpha 13 stimulates Na+-H+ exchange through distinct Cdc42-dependent and RhoA-dependent pathways. (1996) (33)
- Conserved Motifs in Somatostatin, D2-dopamine, and α2B-Adrenergic Receptors for Inhibiting the Na-H Exchanger, NHE1* (2003) (32)
- Regulation of neurotensin release from canine enteric primary cell cultures. (1986) (28)
- Isolated canine ileal mucosal cells in short-term culture: a model for study of neurotensin release. (1986) (27)
- Fatty acids stereospecifically stimulate neurotensin release and increase [Ca2+]i in enteric endocrine cells. (1991) (27)
- Somatostatin and muscarinic inhibition of canine enteric endocrine cells: cellular mechanisms. (1987) (27)
- A Histidine pH sensor regulates activation of the Ras-specific guanine nucleotide exchange factor RasGRP1 (2017) (27)
- β-Catenin is a pH sensor with decreased stability at higher intracellular pH (2018) (26)
- Formin-dependent TGF-β signaling for epithelial to mesenchymal transition (2018) (24)
- Prominent features of the amino acid mutation landscape in cancer (2017) (22)
- A Histidine Cluster in the Cytoplasmic Domain of the Na-H Exchanger NHE1 Confers pH-sensitive Phospholipid Binding and Regulates Transporter Activity* (2016) (22)
- Expression of Actin-interacting Protein 1 Suppresses Impaired Chemotaxis of Dictyostelium Cells Lacking the Na+-H+ Exchanger NHE1 (2010) (22)
- Phosphorylation of the Arp2 Subunit Relieves Auto-inhibitory Interactions for Arp2/3 Complex Activation (2011) (21)
- Phosphorylation of Actin-related Protein 2 (Arp2) Is Required for Normal Development and cAMP Chemotaxis in Dictyostelium* (2012) (21)
- Actin co-sedimentation assay; for the analysis of protein binding to F-actin. (2008) (21)
- Intracellular pH Regulates Cancer and Stem Cell Behaviors: A Protein Dynamics Perspective (2020) (19)
- Characterization of cytoskeletal protein 4.1R interaction with NHE1 (Na(+)/H(+) exchanger isoform 1). (2012) (19)
- Mutant constructs of the beta-adrenergic receptor that are uncoupled from adenylyl cyclase retain functional activation of Na-H exchange. (1992) (18)
- Mislocalized scaffolding by the Na-H exchanger NHE1 dominantly inhibits fibronectin production and TGF-beta activation. (2009) (18)
- Galpha12 differentially regulates Na+-H+ exchanger isoforms. (1996) (16)
- Neurotensin-containing neurons in the canine enteric innervation (1987) (16)
- Hypoxia increases the abundance but not the assembly of extracellular fibronectin during epithelial cell transdifferentiation (2015) (16)
- pHLARE: a new biosensor reveals decreased lysosome pH in cancer cells (2020) (15)
- Intracellular pH dynamics and charge-changing somatic mutations in cancer (2019) (15)
- Nuclear-localized Calcineurin Homologous Protein CHP1 Interacts with Upstream Binding Factor and Inhibits Ribosomal RNA Synthesis* (2010) (12)
- Canine enteric submucosal cultures: Transmitter release from neurotensin-immunoreactive neurons (1989) (12)
- p 160 ROCK mediates RhoA activation of Na – H exchange (2013) (9)
- Tau repeat regions contain conserved histidine residues that modulate microtubule-binding in response to changes in pH (2019) (8)
- Drosophila anion exchanger 2 is required for proper ovary development and oogenesis (2018) (7)
- A minimal cytoplasmic subdomain of the erythropoietin receptor mediates p70 S6 kinase phosphorylation. (2001) (5)
- Effect of Rho GTPases on Na-H exchanger in mammalian cells. (2000) (5)
- [12] Regulation of Na+-H+ exchange by G protein-coupled receptors (1995) (4)
- An acidic residue buried in the dimer interface of isocitrate dehydrogenase 1 (IDH1) helps regulate catalysis and pH sensitivity (2020) (4)
- Low pH Facilitates Heterodimerization of Mutant Isocitrate Dehydrogenase IDH1-R132H and Promotes Production of 2-Hydroxyglutarate (2021) (2)
- Release and characterization of CCK from isolated canine jejunal cells (1983) (2)
- Arp2/3 complex activity is necessary for mouse ESC differentiation, times formative pluripotency, and enables lineage specification (2021) (2)
- pHLARE: A Genetically Encoded Ratiometric Lysosome pH Biosensor (2020) (2)
- Intracellular pH dynamics and charge-changing somatic mutations in cancer (2019) (1)
- Neurotension-containing canine sub-mucosal neurons: Characterisation and response to exogenous stimuli (1986) (1)
- Molecular Mechanisms of RNA Interference (2016) (1)
- Abstract B65: Dissecting the tumor myeloid compartment reveals rare activating antigen presenting cells, critical for T cell immunity (2015) (1)
- Editorial overview: Cell dynamics: Integrating cell dynamics across scales. (2020) (1)
- Ethyl Isopropyl Amiloride Decreases Oxidative Phosphorylation and Increases Mitochondrial Fusion in Clonal Untransformed and Cancer Cells. (2021) (1)
- Near-Infrared Spectroscopy (NIRS) as a Method for Biological Sex Discrimination in the Endangered Houston Toad (Anaxyrus houstonensis) (2021) (1)
- pH dynamics regulates transcription factor-DNA binding. (2023) (0)
- Editorial Board (2009) (0)
- Intracellular pH dynamics regulates intestinal stem cell lineage specification (2021) (0)
- Conserved tau microtubule-binding repeat histidines confer pH-dependent tau-microtubule association (2018) (0)
- blocks F-gp55-dependent transformation. receptor inhibits EPO-dependent growth and A dominant negative erythropoietin (EPO) (2013) (0)
- Molecular Traffic Jams on DNA (2018) (0)
- Arp2/3 Complex Activity Enables Nuclear YAP for Naïve Pluripotency of Human Embryonic Stem Cells (2023) (0)
- Applying sperm collection and cryopreservation protocols developed in a model amphibian to three threatened anuran species targeted for biobanking management (2023) (0)
- Molecular Dynamics Simulations Predict A pH-Dependent Conformational Change in the C-Helix of Cell Cycle Checkpoint Kinase Wee1 (2010) (0)
- Ratiometric Imaging of pH Probes 23 (2014) (0)
- Separation of Epithelial Cells from Gastric and Intestinal Mucosa (1987) (0)
- Regulation of Peptide Secretion from Gastroenteric Endocrine Cells (1993) (0)
- Author response: A Histidine pH sensor regulates activation of the Ras-specific guanine nucleotide exchange factor RasGRP1 (2017) (0)
- Filament assembly by the liver phosphofructokinase‐1, the “gatekeeper” of glycolysis (2020) (0)
- Sperm Cryopreservation as a Tool for Amphibian Conservation: Production of F2 Generation Offspring from Cryo-Produced F1 Progeny (2022) (0)
- Development of tetranucleotide microsatellite loci and a non-invasive DNA sampling method for Texas horned lizards (Phrynosoma cornutum) (2011) (0)
- Crystal structure of human phosphofructokinase-1 in complex with ATP and Mg, Northeast Structural Genomics Consortium Target HR9275 (2015) (0)
- Filament Assembly by Phosphofructokinase-1, the Gatekeeper of Glycolysis (2014) (0)
- Post-thaw sperm motilities in semi-captive versus wild populations of endangered Chiricahua leopard frog (Lithobates chiricahuensis) (2022) (0)
- A Comparative Study of Gamma Subunits of A.Thaliana and O.Sativa (2016) (0)
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