Dieter Mecke
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German biochemist and chemist
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Dieter Meckebiology Degrees
Biology
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#13450
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Biochemistry
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Molecular Biology
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#2667
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Chemistry Biology
Why Is Dieter Mecke Influential?
(Suggest an Edit or Addition)According to Wikipedia, Dieter Mecke was a German biochemist and chemist. Life Dieter Mecke was the fourth of nine children of the physicist Reinhard Mecke, after whom Mecke's symbols have been named. He studied chemistry until 1959 in Freiburg. In his biochemical doctorate he was supervised by Kurt Wallenfels. He worked for one year for Fritz Kaudewitz at the Max Planck Institute in Berlin and returned 1964 to the biochemical institute of the medical faculty, where he habilitated in 1969 in biochemistry. From 1970 to 1971 he was dean and from 1973 professor in Freiburg.
Dieter Mecke's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Heterogeneous distribution of glutamine synthetase among rat liver parenchymal cells in situ and in primary culture. (1983) (353)
- Yeast cell cycle protein CDC48p shows full-length homology to the mammalian protein VCP and is a member of a protein family involved in secretion, peroxisome formation, and gene expression (1991) (296)
- Tyrosine phosphorylation regulates cell cycle-dependent nuclear localization of Cdc48p. (1998) (140)
- Degradation, recycling, and shedding of Trypanosoma brucei variant surface glycoprotein. (1990) (109)
- Different capacities for amino acid transport in periportal and perivenous hepatocytes isolated by digitonin/collagenase perfusion (1989) (95)
- Proteins of Newly Isolated Mutants and the Amino-terminal Proline Are Essential for Ubiquitin-Proteasome-catalyzed Catabolite Degradation of Fructose-1,6-bisphosphatase of Saccharomyces cerevisiae * (1998) (90)
- Mechanism of the enzymatic inactivation of glutamine synthetase from E. coli. (1967) (89)
- Genetic evidence for a role of hexokinase isozyme PII in carbon catabolite repression in Saccharomyces cerevisiae. (1982) (87)
- Chronic Exposure to a GSM-like Signal (Mobile Phone) Does Not Stimulate the Development of DMBA-Induced Mammary Tumors in Rats: Results of Three Consecutive Studies (2002) (85)
- Permissive effect of dexamethasone on glucagon induction of urea-cycle enzymes in perifused primary monolayer cultures of rat hepatocytes. (1979) (82)
- Differentiation of Trypanosoma brucei bloodstream trypomastigotes from long slender to short stumpy-like forms in axenic culture. (1990) (82)
- Perifused monolayer cultures of rat hepatocytes as an improved in vitro system for studies on ureogenesis. (1979) (77)
- Seasonality of pineal melatonin production in the rat: possible synchronization by the geomagnetic field. (1994) (77)
- The primary structure of the yeast hexokinase PII gene (HXK2) which is responsible for glucose repression. (1985) (73)
- An improved method for the isolation of hepatocytes from liver slices. Selective removal of Trypan blue-dyeable cells. (1977) (72)
- The Pineal Gland and Cancer (2001) (61)
- Nocturnal urinary 6‐sulphatoxymelatonin excretion is decreased in primary breast cancer patients compared to age‐matched controls and shows negative correlation with tumor‐size (1997) (59)
- Complete nucleotide sequence of the hexokinase PI gene (HXK1) of Saccharomyces cerevisiae. (1985) (58)
- The ATPase activity of purified CDC48p from Saccharomyces cerevisiae shows complex dependence on ATP-, ADP-, and NADH-concentrations and is completely inhibited by NEM. (1995) (58)
- Alterations of hepatic enzyme levels and of the acinar distribution of glutamine synthetase in response to experimental liver injury in the rat (1988) (57)
- Arenaemycin (pentalenolactone): a specific inhibitor of glycolysis (1978) (56)
- Induction of glutamine synthetase in periportal hepatocytes by cocultivation with a liver epithelial cell line. (1990) (53)
- Evidence for catabolite degradation in the glucose-dependent inactivation of yeast cytoplasmic malate dehydrogenase. (1978) (52)
- Metabolic and enzymatic characteristics of adult rat liver parenchymal cells in non-proliferating primary monolayer cultures. (1978) (52)
- The role of growth hormone, dexamethasone and triiodothyronine in the regulation of glutamine synthetase in primary cultures of rat hepatocytes. (1979) (51)
- Cloning of hexokinase structural genes from Saccharomyces cerevisiae mutants with regulatory mutations responsible for glucose repression (1985) (50)
- Characterization of a glutamine synthetase inactivating enzyme from Escherichia coli. (1966) (49)
- Purification and characterization of rat liver glutaminase. (1987) (48)
- Diminished Pineal Function Coincides with Disturbed Circadian Endocrine Rhythmicity in Untreated Primary Cancer Patients (1994) (47)
- Cellular Distribution and Regulation of Glutamine Synthetase in Liver (1984) (45)
- The Malate Dehydrogenase Isoenzymes of Saccharomyces cerevisiae (1978) (44)
- Heterogeneous (positional) expression of hepatic glutamine synthetase: features, regulation and implications for hepatocarcinogenesis. (1994) (40)
- Effect of melatonin and pineal extracts on human ovarian and mammary tumor cells in a chemosensitivity assay. (2000) (37)
- Expression and regulation of glycogen phosphorylase in preneoplastic and neoplastic hepatic lesions in rats (1987) (36)
- Regulation of enzymes and isoenzymes of carbohydrate metabolism in the yeast Saccharomyces cerevisiae. (1984) (36)
- Glutamate uptake by cultured rat hepatocytes is mediated by hormonally inducible, sodium‐dependent transport systems (1983) (34)
- Serial Transplants of DMBA-Induced Mammary Tumors in Fischer Rats as a Model System for Human Breast Cancer (1999) (34)
- Glial fibrillary acidic protein‐positive cells of the kidney are capable of raising a protective biochemical barrier similar to astrocytes: Expression of metallothionein in podocytes (2002) (33)
- A convenient and highly sensitive spectrophotometric assay for tryptophan 2,3-dioxygenase. (1982) (29)
- Alterations in activity and ultrastructural localization of several phosphatases on the surface of adult rat hepatocytes in primary monolayer culture. (1982) (28)
- Nocturnal urinary 6‐sulfatoxymelatonin and proliferating cell nuclear antigen‐immunopositive tumor cells show strong positive correlations in patients with gastrointestinal and lung cancer (1997) (28)
- Substitution of a pentalenolactone-sensitive glyceraldehyde-3-phosphate dehydrogenase by a genetically distinct resistant isoform accompanies pentalenolactone production in Streptomyces arenae (1989) (27)
- Studies on the regulation of enolases and compartmentation of cytosolic enzymes in Saccharomyces cerevisiae. (1987) (27)
- Metabolite-induced enzymatic inactivation of glutamine synthetase in E. coli. (1967) (27)
- Characterization of two glyceraldehyde-3-phosphate dehydrogenase isoenzymes from the pentalenolactone producer Streptomyces arenae (1983) (26)
- Effect of chronic exposure to a GSM-like signal (mobile phone) on survival of female Sprague-Dawley rats: modulatory effects by month of birth and possibly stage of the solar cycle. (2010) (25)
- Inhibition of spinach glyceraldehyde-3-phosphate dehydrogenases by pentalenolactone (1979) (25)
- Dexamethasone restores hormonal inducibility of ornithine decarboxylase in primary cultures of rat hepatocytes. (1985) (24)
- Irreversible inactivation of Saccharomyces cerevisiae fructose‐1,6‐bisphosphatase independent of protein phosphorylation at Ser11 (1988) (24)
- Specific inactivation of glucose metabolism from eucaryotic cells by pentalenolactone. (1982) (23)
- Common myofibroblastic features of newborn rat astrocytes and cirrhotic rat liver stellate cells in early cultures and in vivo (1999) (23)
- Dihydrolipoamide transacetylase from Escherichia Coli: evidence for internal gene duplication. (1978) (21)
- Serial transplants of DMBA-induced mammary tumors in Fischer rats as model system for human breast cancer. IV. Parallel changes of biopterin and melatonin indicate interactions between the pineal gland and cellular immunity in malignancy. (1995) (20)
- Cloning and sequence of the mdh structural gene of Escherichia coli coding for malate dehydrogenase (2004) (19)
- Cloning, Heterologous Expression and Kinetic Analysis of Glycerol Kinase (TbGLK1) from Trypanosoma brucei (2000) (19)
- l-Glutamine Determination with Glutamine Synthetase (1974) (19)
- Gene cloning and sequencing, and enzyme purification of the malate synthase of Streptomyces arenae. (1997) (19)
- Regulation of two forms of glutamine synthetase in Escherichia coli by the ammonia content of the growth medium. (1968) (18)
- Inhibition of glyceraldehyde-3-phosphate dehydrogenase by pentalenolactone in Trypanosoma brucei. (1986) (18)
- Influence of hormones and drugs on glutathione-S-transferase levels in primary culture of adult rat hepatocytes (1990) (18)
- Isolation and characterization of nuclei and nuclear membranes from saccharomyces cerevisiae protoplasts (1980) (17)
- Reestablishment of the heterogeneous distribution of hepatic glutamine synthetase during regeneration after CCl4-intoxication (2004) (17)
- Application of an immunoassay to the study of yeast malate dehydrogenase inactivation. (1978) (16)
- Studies on rapid reversible and non-reversible inactivation of fructose-1,6-bisphosphatase and malate dehydrogenase in wild-type and glycolytic block mutants of Saccharomyces cerevisiae (1983) (15)
- Different drug metabolizing capacities in cultured periportal and pericentral hepatocytes. (1994) (15)
- Cloning of hexokinase isoenzyme PI from Saccharomyces cerevisiae: PI transformants confirm the unique role of hexokinase isoenzyme PII for glucose repression in yeasts (2004) (15)
- Pentalenolactone-insensitive glyceraldehyde-3-phosphate dehydrogenase fromStreptomyces arenae is closely related to GAPDH from thermostable eubacteria and plant chloroplasts (1996) (12)
- Search for Seasonal Rhythmicity of Pineal Melatonin Production in Rats Under Constant Laboratory Conditions: Spectral Chronobiological Analysis, and Relation to Solar and Geomagnetic Variables (2012) (12)
- Seasonal rhythms of 6‐sulphatoxymelatonin (aMT6s) excretion in female rats are abolished by growth of malignant tumors (2001) (12)
- Cloning and restriction analysis of the hexokinase PII gene of the yeast Saccharomyces cerevisiae (2004) (11)
- Purification procedure and N-terminal amino acid sequence of yeast malate dehydrogenase isoenzymes. (1987) (10)
- The Relationship between the Pineal Gland and Cancer: Seasonal Aspects (1993) (10)
- The isolation of Saccharomyces cerevisiae nuclear membranes with nuclease and high-salt treatment. (1982) (10)
- Purification of three distinct enolase isoenzymes from yeast. (1983) (9)
- Regulation of enzymes involved in the biosynthesis of the sesquiterpene antibiotic pentalenolactone in Streptomyces arenae. (1986) (9)
- Serial transplants of DMBA-induced mammary tumors in fischer rats as model system for human breast cancer: V. Myoepithelial-mesenchymal conversion during passaging as possible cause for modulation of pineal-tumor interaction. (2000) (9)
- Hepatic hydroxylation of melatonin in the rat is induced by phenobarbital and 7,12-dimethylbenzy[a]anthracene — implications for cancer etiology (1995) (8)
- The Triton X-100 and High Salt Resistant Residue of Saccharomyces cerevisiae Nuclear Membranes (1982) (7)
- Dynamics of glial fibrillary acidic protein distribution in cultured glomerular podocytes and mesangial cells of the rat kidney (1999) (7)
- The malate dehydrogenase isoenzymes of Saccharomyces cerevisiae. Purification, characterisation and studies on their regulation. (1978) (6)
- Modulation of pineal activity during the 23rd sunspot cycle: melatonin rise during the ascending phase of the cycle is accompanied by an increase of the sympathetic tone. (2014) (5)
- Activation of glutaminase by phosphoribosyl-pyrophosphate and its interference with the assay of phosphoribosylpyrophosphate amidotransferase. (1979) (5)
- Melatonin in Patients with Cancer of Extra-Reproductive Location (2001) (5)
- Analysis of Melatonin in Patients with Cancer of the Reproductive System (2001) (5)
- Longitudinal melatonin production in female laboratory rats during 1997-2006: possible modulatory effects of changing solar activity. (2013) (5)
- pSAR1, a natural plasmid from Streptomyces arenae, shows rapid increase and decrease of copy numbers on changes of growth media. (1991) (5)
- Spermidine level and protein synthesis are coregulated in nonproliferating hepatocytes. (1989) (4)
- The Modulation of Melatonin in Tumor-Bearing Animals: Underlying Mechanisms and Possible Significance for Prognosis (2001) (4)
- In vivo and in vitro studies on the glucose dependent inactivation of yeast cytoplasmic malate dehydrogenase (1977) (3)
- Intercellular Compartmentation of Hepatic Ammonia Metabolism: A Basis for the Differential Regulatory Influence of Hormones on Related Enzymes and Amino Acid Transport Systems? (1984) (3)
- [Repression and inactivation of glutamine synthetase in Escherichia coli by NH4+]. (1966) (2)
- An easy and fast alternative to plasmid shuffling for the identification of in vitro mutagenized alleles of essential genes of Saccharomyces cerevisiae. (1992) (2)
- Glomerular Podocytes Express Metallothionein Similar to Astrocytes (1999) (2)
- DEVELOPMENT OF BILIARY MEMBRANE DIFFERENTIATION IN CULTURED HEPATOCYTES (1981) (1)
- Notiz über Hexabromotitanate (1958) (1)
- Effect of insulin on glycogen and protein synthesis in monolayer cultures of hepatocytes from normal and alloxan diabetic rats (1977) (1)
- [Comparison of several forms of glutamine synthetase from Escherichia coli]. (1968) (0)
- [Inactivation of malate dehydrogenase in yeast]. (1972) (0)
- Demonstration and characterization of galactosyltransferase in Trypanosoma brucei brucei. (1990) (0)
- [Glutamine synthetase activity in the liver in primary gout (author's transl)]. (1974) (0)
- The Triton X-100 and High Salt Resistant Residue of Saccharomyces cerevisiae Nuclear Membranes, II / Isolation of the Nuclear Membrane Insoluble Residue from G1 Arrested Cells and Immunological Comparison with the Corresponding Vertebrate Nuclear Fraction (1984) (0)
- Dynamics of glial fibrillary acidic protein distribution in cultured glomerular podocytes and mesangial cells of the rat kidney. (1999) (0)
- [Reactivation of ammonium-inactivated glutamine synthetase in Escherichia coli]. (1967) (0)
- POSSIBLE MODES OF ACTION OF BSA ON ENZYME LEVELS IN CULTURED HEPATOCYTES (1981) (0)
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