Dik-lung Edmond. Ma
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(Suggest an Edit or Addition)Dik-lung Edmond. Ma's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- New Perspectives on How to Discover Drugs from Herbal Medicines: CAM's Outstanding Contribution to Modern Therapeutics (2013) (521)
- Bioactive luminescent transition-metal complexes for biomedical applications. (2013) (284)
- Stabilization of G-quadruplex DNA and down-regulation of oncogene c-myc by quindoline derivatives. (2007) (260)
- Recent advances in luminescent heavy metal complexes for sensing (2012) (241)
- Platinum(II) complexes with dipyridophenazine ligands as human telomerase inhibitors and luminescent probes for G-quadruplex DNA. (2009) (240)
- Bioactive iridium and rhodium complexes as therapeutic agents (2013) (233)
- A highly selective luminescent switch-on probe for histidine/histidine-rich proteins and its application in protein staining. (2008) (199)
- Group 9 organometallic compounds for therapeutic and bioanalytical applications. (2014) (199)
- Drug repositioning by structure-based virtual screening. (2013) (196)
- Label-free luminescent oligonucleotide-based probes. (2013) (184)
- Luminescence switch-on detection of protein tyrosine kinase-7 using a G-quadruplex-selective probe† †Electronic supplementary information (ESI) available: Compound characterisation and supplementary data. See DOI: 10.1039/c5sc01320h Click here for additional data file. (2015) (152)
- Some uses of transition metal complexes as anti-cancer and anti-HIV agents. (2007) (146)
- A metal-based inhibitor of tumor necrosis factor-α. (2012) (142)
- G-quadruplexes for luminescent sensing and logic gates (2013) (141)
- Conjugating a groove-binding motif to an Ir(iii) complex for the enhancement of G-quadruplex probe behavior† †Electronic supplementary information (ESI) available: Compound characterisation and supplementary data. See DOI: 10.1039/c6sc00001k (2016) (140)
- Recent Developments in G-Quadruplex Probes. (2015) (139)
- Stabilization of G-quadruplex DNA with platinum(II) Schiff base complexes: luminescent probe and down-regulation of c-myc oncogene expression. (2009) (138)
- Cyclometalated gold(III) complexes with N-heterocyclic carbene ligands as topoisomerase I poisons. (2010) (138)
- Alisol B, a Novel Inhibitor of the Sarcoplasmic/Endoplasmic Reticulum Ca2+ ATPase Pump, Induces Autophagy, Endoplasmic Reticulum Stress, and Apoptosis (2010) (133)
- Label-free luminescence switch-on detection of hepatitis C virus NS3 helicase activity using a G-quadruplex-selective probe† †Electronic supplementary information (ESI) available: Compound characterisation and supplementary data. See DOI: 10.1039/c4sc03319a Click here for additional data file. (2014) (129)
- Luminescent chemosensors by using cyclometalated iridium(iii) complexes and their applications (2016) (125)
- Detection of nicking endonuclease activity using a G-quadruplex-selective luminescent switch-on probe (2014) (125)
- Cyclometalated platinum(II) complexes as highly sensitive luminescent switch-on probes for practical application in protein staining and cell imaging. (2009) (124)
- DNA binding and cytotoxicity of ruthenium(II) and rhenium(I) complexes of 2-amino-4-phenylamino-6-(2-pyridyl)-1,3,5-triazine. (2007) (121)
- Stable anticancer gold(III)-porphyrin complexes: effects of porphyrin structure. (2010) (120)
- Molecular docking for virtual screening of natural product databases (2011) (118)
- 5-N-methylated quindoline derivatives as telomeric g-quadruplex stabilizing ligands: effects of 5-N positive charge on quadruplex binding affinity and cell proliferation. (2008) (117)
- A bifunctional platinum(II) complex capable of intercalation and hydrogen-bonding interactions with DNA: binding studies and cytotoxicity. (2003) (116)
- Detection of base excision repair enzyme activity using a luminescent G-quadruplex selective switch-on probe. (2013) (114)
- Antagonizing STAT3 dimerization with a rhodium(III) complex. (2014) (114)
- Label-free luminescence switch-on detection of T4 polynucleotide kinase activity using a G-quadruplex-selective probe. (2014) (112)
- Group 9 metal-based inhibitors of β-amyloid (1–40) fibrillation as potential therapeutic agents for Alzheimer's disease (2011) (109)
- TLR-4 may mediate signaling pathways of Astragalus polysaccharide RAP induced cytokine expression of RAW264.7 cells. (2016) (108)
- Structure-based discovery of natural-product-like TNF-α inhibitors. (2010) (106)
- Water soluble luminescent platinum terpyridine complexes with glycosylated acetylide and arylacetylide ligands: photoluminescent properties and cytotoxicities. (2005) (102)
- Structure-based design of platinum(II) complexes as c-myc oncogene down-regulators and luminescent probes for G-quadruplex DNA. (2010) (102)
- Simple and convenient G-quadruplex-based turn-on fluorescence assay for 3' → 5' exonuclease activity. (2011) (101)
- Development of a Long-Lived Luminescence Probe for Visualizing β-Galactosidase in Ovarian Carcinoma Cells. (2017) (101)
- Simple DNA-based logic gates responding to biomolecules and metal ions (2013) (100)
- Identification of a natural product-like STAT3 dimerization inhibitor by structure-based virtual screening (2014) (98)
- Metal complexes as potential modulators of inflammatory and autoimmune responses (2014) (97)
- Structure Characterization and Immunomodulating Effects of Polysaccharides Isolated from Dendrobium officinale. (2016) (96)
- Selective Inhibition of Lysine-Specific Demethylase 5A (KDM5A) Using a Rhodium(III) Complex for Triple-Negative Breast Cancer Therapy. (2018) (95)
- A luminescent G-quadruplex switch-on probe for the highly selective and tunable detection of cysteine and glutathione. (2013) (94)
- A long lifetime luminescent iridium(III) complex chemosensor for the selective switch-on detection of Al(3+) ions. (2016) (93)
- Proteomic and transcriptomic study on the action of a cytotoxic saponin (Polyphyllin D): Induction of endoplasmic reticulum stress and mitochondria‐mediated apoptotic pathways (2008) (92)
- A highly selective G-quadruplex-based luminescent switch-on probe for the detection of gene deletion. (2012) (91)
- Inhibition of the Ras/Raf interaction and repression of renal cancer xenografts in vivo by an enantiomeric iridium(iii) metal-based compound† †Electronic supplementary information (ESI) available: Synthetic methods, characterization, and biological assays details. See DOI: 10.1039/c7sc00311k Click h (2017) (91)
- Development of an Iridium(III) Complex as a G-Quadruplex Probe and Its Application for the G-Quadruplex-Based Luminescent Detection of Picomolar Insulin. (2016) (90)
- An oligonucleotide-based switch-on luminescent probe for the detection of kanamycin in aqueous solution (2013) (88)
- Transition metal complexes as electrocatalysts : Development and applications in electro-oxidation reactions (2007) (87)
- A highly selective, label-free, homogenous luminescent switch-on probe for the detection of nanomolar transcription factor NF-kappaB (2011) (87)
- Luminescent detection of DNA-binding proteins (2011) (87)
- Cell imaging of dopamine receptor using agonist labeling iridium(iii) complex† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c7sc04798c (2017) (86)
- Structure-based optimization of FDA-approved drug methylene blue as a c-myc G-quadruplex DNA stabilizer. (2011) (85)
- Label-free detection of sub-nanomolar lead(II) ions in aqueous solution using a metal-based luminescent switch-on probe. (2013) (82)
- Dual function luminescent transition metal complexes for cancer theranostics: The combination of diagnosis and therapy (2019) (82)
- Pharmacological Inhibition of LSD1 for Cancer Treatment (2018) (81)
- A long lifetime iridium(III) complex as a sensitive luminescent probe for bisulfite detection in living zebrafish (2017) (77)
- A gold(III) porphyrin complex with antitumor properties targets the Wnt/beta-catenin pathway. (2010) (77)
- A natural product-like inhibitor of NEDD8-activating enzyme. (2011) (77)
- A selective G-quadruplex-based luminescent switch-on probe for the detection of nanomolar silver(I) ions in aqueous solution. (2010) (76)
- Oligonucleotide-based luminescent detection of metal ions. (2011) (75)
- Ultrasensitive electrochemical detection of miRNA-21 by using an iridium(III) complex as catalyst. (2016) (73)
- Identification of natural product fonsecin B as a stabilizing ligand of c-myc G-quadruplex DNA by high-throughput virtual screening. (2010) (73)
- A MnO2 nanosheet-assisted GSH detection platform using an iridium(iii) complex as a switch-on luminescent probe. (2017) (72)
- Alkene cyclopropanation catalyzed by Halterman iron porphyrin: participation of organic bases as axial ligands. (2006) (71)
- A label-free G-quadruplex-based switch-on fluorescence assay for the selective detection of ATP. (2012) (71)
- A selective oligonucleotide-based luminescent switch-on probe for the detection of nanomolar mercury(II) ion in aqueous solution. (2009) (70)
- A long lifetime switch-on iridium(III) chemosensor for the visualization of cysteine in live zebrafish. (2016) (69)
- Crystal violet as a fluorescent switch-on probe for i-motif: label-free DNA-based logic gate. (2011) (68)
- Recent development of transition metal complexes with in vivo antitumor activity. (2017) (68)
- Combination of i-motif and G-quadruplex structures within the same strand: formation and application. (2013) (67)
- Determination of cell metabolite VEGF₁₆₅ and dynamic analysis of protein-DNA interactions by combination of microfluidic technique and luminescent switch-on probe. (2016) (64)
- Identification of a New Class of FtsZ Inhibitors by Structure-Based Design and in Vitro Screening (2013) (61)
- An anti-prostate cancer benzofuran-conjugated iridium(III) complex as a dual inhibitor of STAT3 and NF-κB. (2017) (58)
- An iridium(iii)-based irreversible protein–protein interaction inhibitor of BRD4 as a potent anticancer agent† †Electronic supplementary information (ESI) available: Synthetic methods, characterization and biological assays details. See DOI: 10.1039/c5sc02321a Click here for additional data file. (2015) (56)
- A Rhodium(III) Complex as an Inhibitor of Neural Precursor Cell Expressed, Developmentally Down-Regulated 8-Activating Enzyme with in Vivo Activity against Inflammatory Bowel Disease. (2017) (55)
- Label-free luminescent switch-on detection of endonuclease IV activity using a G-quadruplex-selective iridium(III) complex. (2013) (54)
- A Rhodium(III)-Based Inhibitor of Lysine-Specific Histone Demethylase 1 as an Epigenetic Modulator in Prostate Cancer Cells. (2017) (53)
- Platycodin D induces apoptosis and triggers ERK- and JNK-mediated autophagy in human hepatocellular carcinoma BEL-7402 cells (2015) (53)
- A dicationic organoplatinum(II) complex containing a bridging 2,5-bis-(4-ethynylphenyl)-[1,3,4]oxadiazole ligand behaves as a phosphorescent gelator for organic solvents. (2008) (52)
- A colorimetric chemosensor for Cu2+ ion detection based on an iridium(III) complex (2014) (51)
- Visualization of Zn²⁺ ions in live zebrafish using a luminescent iridium(III) chemosensor. (2014) (51)
- Interaction of an Iridium(III) Complex with G-Quadruplex DNA and Its Application in Luminescent Switch-On Detection of Siglec-5. (2016) (51)
- An oligonucleotide-based label-free luminescent switch-on probe for RNA detection utilizing a G-quadruplex-selective iridium(III) complex. (2014) (51)
- An Iridium(III) Complex Inhibits JMJD2 Activities and Acts as a Potential Epigenetic Modulator. (2015) (50)
- Development of an Aptamer-Based Sensing Platform for Metal Ions, Proteins, and Small Molecules through Terminal Deoxynucleotidyl Transferase Induced G-Quadruplex Formation. (2015) (50)
- Discovery of a natural product inhibitor targeting protein neddylation by structure-based virtual screening. (2012) (50)
- 2-Methoxy-6-acetyl-7-methyljuglone (MAM), a natural naphthoquinone, induces NO-dependent apoptosis and necroptosis by H2O2-dependent JNK activation in cancer cells. (2016) (50)
- Specific blocking of CREB/DNA binding by cyclometalated platinum(II) complexes. (2011) (49)
- A small molecule HIF-1α stabilizer that accelerates diabetic wound healing (2021) (49)
- DNA‐Binding Small Molecules as Inhibitors of Transcription Factors (2013) (49)
- Butyrate mediates nucleotide‐binding and oligomerisation domain (NOD) 2‐dependent mucosal immune responses against peptidoglycan (2009) (48)
- A luminescence switch-on probe for terminal deoxynucleotidyl transferase (TdT) activity detection by using an iridium(III)-based i-motif probe. (2015) (47)
- Flavonoid Dimers as Bivalent Modulators for P‐Glycoprotein‐Based Multidrug Resistance: Structure–Activity Relationships (2009) (47)
- Discovery of a Drug‐Like G‐Quadruplex Binding Ligand by High‐Throughput Docking (2008) (47)
- Molecular modeling of drug-DNA interactions: virtual screening to structure-based design. (2011) (47)
- New perspectives on innovative drug discovery: an overview. (2010) (46)
- Structure-based discovery of an immunomodulatory inhibitor of TLR1-TLR2 heterodimerization from a natural product-like database. (2015) (46)
- Virtual screening and optimization of Type II inhibitors of JAK2 from a natural product library. (2014) (45)
- The application of a G-quadruplex based assay with an iridium(iii) complex to arsenic ion detection and its utilization in a microfluidic chip. (2017) (45)
- Identification of an iridium(III) complex with anti-bacterial and anti-cancer activity (2015) (45)
- Metal complexes for the detection of disease-related protein biomarkers (2016) (45)
- Luminescent oligonucleotide-based detection of enzymes involved with DNA repair (2013) (44)
- Identification of an Iridium(III)-Based Inhibitor of Tumor Necrosis Factor-α. (2016) (44)
- Luminescence switch-on assay of interferon-gamma using a G-quadruplex-selective iridium(III) complex. (2015) (43)
- Synthesis and Biological Activity of a Platinum(II) 6‐Phenyl‐2,2′‐bipyridine Complex and Its Dimeric Analogue (2003) (43)
- Discovery of a Natural Product-Like iNOS Inhibitor by Molecular Docking with Potential Neuroprotective Effects In Vivo (2014) (42)
- A suspending-droplet mode paper-based microfluidic platform for low-cost, rapid, and convenient detection of lead(II) ions in liquid solution. (2018) (42)
- Structure-based identification of a NEDD8-activating enzyme inhibitor via drug repurposing. (2018) (42)
- A long-lived peptide-conjugated iridium(iii) complex as a luminescent probe and inhibitor of the cell migration mediator, formyl peptide receptor 2† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8sc02733a (2018) (42)
- Iridium(III) Complexes Targeting Apoptotic Cell Death in Cancer Cells (2019) (42)
- Luminescent iridium(iii) complexes as COX-2-specific imaging agents in cancer cells. (2017) (41)
- Label-Free Luminescent Switch-On Probe for Ochratoxin A Detection Using a G-Quadruplex-Selective Iridium(III) Complex. (2015) (40)
- A versatile nanomachine for the sensitive detection of platelet-derived growth factor-BB utilizing a G-quadruplex-selective iridium(III) complex. (2016) (40)
- Anti-Fatigue Effects of the Unique Polysaccharide Marker of Dendrobium officinale on BALB/c Mice (2017) (40)
- Psoralidin induced reactive oxygen species (ROS)-dependent DNA damage and protective autophagy mediated by NOX4 in breast cancer cells. (2016) (40)
- Cucurbitacin E induces caspase-dependent apoptosis and protective autophagy mediated by ROS in lung cancer cells. (2016) (40)
- Structure-Based Discovery of a Selective KDM5A Inhibitor that Exhibits Anti-Cancer Activity via Inducing Cell Cycle Arrest and Senescence in Breast Cancer Cell Lines (2019) (40)
- Luminescent G-quadruplex probes. (2012) (40)
- Structure‐Based Repurposing of FDA‐Approved Drugs as TNF‐α Inhibitors (2011) (39)
- Discovery of a Natural Product-Like c-myc G-Quadruplex DNA Groove-Binder by Molecular Docking (2012) (38)
- The design and development of covalent protein-protein interaction inhibitors for cancer treatment (2020) (38)
- Glycyrrhetinic acid induces cytoprotective autophagy via the inositol-requiring enzyme 1α-c-Jun N-terminal kinase cascade in non-small cell lung cancer cells (2015) (38)
- Switching on the Phosphorescence of Pyrene by Cycloplatination (2009) (38)
- A highly selective G-quadruplex-based luminescent switch-on probe for the detection of nanomolar strontium(II) ions in sea water (2012) (37)
- A natural product-like JAK2/STAT3 inhibitor induces apoptosis of malignant melanoma cells (2017) (37)
- Synthesis and Electronic Spectroscopy of Luminescent Cyclometalated Platinum−Anthracenyl Complexes (2007) (37)
- Biofunctional Activities of Equisetum ramosissimum Extract: Protective Effects against Oxidation, Melanoma, and Melanogenesis (2016) (37)
- A long-lived phosphorescence iridium(III) complex as a switch on-off-on probe for live zebrafish monitoring of endogenous sulfide generation. (2017) (36)
- Metal complexes as inhibitors of transcription factor activity (2013) (36)
- The emerging role of KDM5A in human cancer (2021) (34)
- Iridium(iii) complexes with 1,10-phenanthroline-based N^N ligands as highly selective luminescent G-quadruplex probes and application for switch-on ribonuclease H detection. (2016) (34)
- Inhibition of Beta-Amyloid Fibrillation by Luminescent Iridium(III) Complex Probes (2015) (34)
- A Metal-Based Inhibitor of NEDD8-Activating Enzyme (2012) (34)
- Emerging Screening Approaches in the Development of Nrf2–Keap1 Protein–Protein Interaction Inhibitors (2019) (33)
- Identification of a rhodium(iii) complex as a Wee1 inhibitor against TP53-mutated triple-negative breast cancer cells. (2018) (33)
- Phosphorescent Imaging of Living Cells Using a Cyclometalated Iridium(III) Complex (2013) (33)
- Utilization of G-Quadruplex-Forming Aptamers for the Construction of Luminescence Sensing Platforms. (2017) (33)
- A G-quadruplex-selective luminescent probe with an anchor tail for the switch-on detection of thymine DNA glycosylase activity. (2016) (33)
- Discovery of a VHL and HIF1α interaction inhibitor with in vivo angiogenic activity via structure-based virtual screening. (2016) (33)
- Metal-indolizine zwitterion complexes as a new class of organometallic material: A spectroscopic and theoretical investigation (2014) (32)
- Recent advances in iridium(iii) complex-assisted nanomaterials for biological applications. (2018) (32)
- A G-quadruplex-selective luminescent switch-on probe for the detection of sub-nanomolar human neutrophil elastase (2013) (32)
- Rhodium complexes as therapeutic agents. (2016) (31)
- Organoplatinum(II) complexes with nucleobase motifs as inhibitors of human topoisomerase II catalytic activity. (2010) (31)
- Recent Development of G-Quadruplex Probes for Cellular Imaging. (2015) (31)
- A Luminescent Cocaine Detection Platform Using a Split G-Quadruplex-Selective Iridium(III) Complex and a Three-Way DNA Junction Architecture. (2015) (31)
- Fluorophore-labeled beta-lactamase as a biosensor for beta-lactam antibiotics: a study of the biosensing process. (2008) (31)
- Pathologically Activated Neuroprotection via Uncompetitive Blockade of N-Methyl-d-aspartate Receptors with Fast Off-rate by Novel Multifunctional Dimer Bis(propyl)-cognitin* (2010) (31)
- Label-free sensing of pH and silver nanoparticles using an "OR" logic gate. (2012) (30)
- Anticancer osmium complex inhibitors of the HIF-1α and p300 protein-protein interaction (2017) (30)
- Isocryptotanshinone, a STAT3 inhibitor, induces apoptosis and pro-death autophagy in A549 lung cancer cells (2016) (30)
- A Colorimetric and Luminescent Dual-Modal Assay for Cu(II) Ion Detection Using an Iridium(III) Complex (2014) (30)
- Bis-intercalative dinuclear platinum(II) 6-phenyl-2,2′-bipyridine complexes exhibit enhanced DNA affinity but similar cytotoxicity compared to the mononuclear unit (2003) (30)
- In silico screening of quadruplex-binding ligands. (2012) (30)
- Small Molecule Pin1 Inhibitor Blocking NF-κB Signaling in Prostate Cancer Cells. (2018) (29)
- Structure-based screening and optimization of cytisine derivatives as inhibitors of the menin-MLL interaction. (2016) (29)
- Silencing Stem Cell Factor Gene in Fibroblasts to Regulate Paracrine Factor Productions and Enhance c-Kit Expression in Melanocytes on Melanogenesis (2018) (28)
- Antagonism of mTOR Activity by a Kinetically Inert Rhodium(III) Complex. (2014) (28)
- Gold-Catalyzed Cycloisomerization and Diels-Alder Reaction of 1,4,9-Dienyne Esters to 3 a,6-Methanoisoindole Esters with Pro-Inflammatory Cytokine Antagonist Activity. (2015) (28)
- A dual-functional molecular strategy for in situ suppressing and visualizing of neuraminidase in aqueous solution using iridium(iii) complexes. (2019) (28)
- A luminescent G-quadruplex-selective iridium(iii) complex for the label-free detection of lysozyme. (2016) (28)
- An Individual Nanocube-Based Plasmonic Biosensor for Real-Time Monitoring the Structural Switch of the Telomeric G-Quadruplex. (2016) (27)
- First Synthesis of an Oridonin-Conjugated Iridium(III) Complex for the Intracellular Tracking of NF-κB in Living Cells. (2017) (27)
- Inhibition of Janus kinase 2 by cyclometalated rhodium complexes (2012) (27)
- Platycodin D potentiates proliferation inhibition and apoptosis induction upon AKT inhibition via feedback blockade in non-small cell lung cancer cells (2016) (27)
- PTEN Activation by DNA Damage Induces Protective Autophagy in Response to Cucurbitacin B in Hepatocellular Carcinoma Cells (2016) (26)
- Aberrant JAK/STAT Signaling Suppresses TFF1 and TFF2 through Epigenetic Silencing of GATA6 in Gastric Cancer (2016) (26)
- A long-lived luminogenic iridium(III) complex for acetylacetone detection in environmental samples (2020) (26)
- The Development of G-Quadruplex-Based Assays for the Detection of Small Molecules and Toxic Substances. (2017) (26)
- A metal-based tumour necrosis factor-alpha converting enzyme inhibitor. (2015) (26)
- Application of iridium(III) complex in label-free and non-enzymatic electrochemical detection of hydrogen peroxide based on a novel “on-off-on” switch platform (2016) (26)
- An iridium(III) complex-based chemosensor for the detection of thiourea in living cells (2017) (25)
- A parallel G-quadruplex-selective luminescent probe for the detection of nanomolar calcium(II) ion. (2013) (25)
- Luminescent detection of human serum albumin in aqueous solution using a cyclometallated iridium(III) complex (2014) (25)
- An Ir(III) complex chemosensor for the detection of thiols (2016) (24)
- Dual Inhibition And Monitoring Of Beta-amyloid Fibrillation By A Luminescent Iridium(III) Complex. (2015) (24)
- A label-free G-quadruplex-based luminescent switch-on assay for the selective detection of histidine. (2013) (24)
- Luminescent Iridium(III) Chemosensor for Tandem Detection of F– and Al3+ (2017) (24)
- Construction of a Nano Biosensor for Cyanide Anion Detection and Its Application in Environmental and Biological Systems. (2017) (23)
- Aminoglycosylation Can Enhance the G-Quadruplex Binding Activity of Epigallocatechin (2013) (23)
- An Aldol Reaction-Based Iridium(III) Chemosensor for the Visualization of Proline in Living Cells (2016) (23)
- Luminescent turn-on detection of Hg(II) via the quenching of an iridium(III) complex by Hg(II)-mediated silver nanoparticles (2017) (23)
- Silver nanoclusters functionalized with Ce(III) ions are a viable “turn-on-off” fluorescent probe for sulfide (2018) (22)
- Luminescent cyclometalated platinum(II) complexes with amino acid ligands for protein binding. (2005) (22)
- G-quadruplex-based logic gates for HgII and AgI ions employing a luminescent iridium(iii) complex and extension of metal-mediated base pairs by polymerase. (2015) (22)
- Synergistic Effects of Linderanolide B Combined with Arbutin, PTU or Kojic Acid on Tyrosinase Inhibition. (2015) (22)
- Development of Natural Product-Conjugated Metal Complexes as Cancer Therapies (2019) (21)
- Turn-on Luminescent Probe for Hydrogen Peroxide Sensing and Imaging in Living Cells based on an Iridium(III) Complex–Silver Nanoparticle Platform (2017) (21)
- A dual-functional luminescent probe for imaging H2S in living zebrafish and discrimination hypoxic cells from normoxic cells (2018) (21)
- Hit identification of IKKβ natural product inhibitor (2013) (20)
- A tutorial review for employing enzymes for the construction of G-quadruplex-based sensing platforms. (2016) (20)
- Rebalancing metal dyshomeostasis for Alzheimer’s disease therapy (2019) (20)
- Peptide-conjugated long-lived theranostic imaging toolbox for targeting GRPr in cancer and immune cells. (2020) (20)
- Inhibition of the CDK9–cyclin T1 protein–protein interaction as a new approach against triple-negative breast cancer (2021) (20)
- A G-quadruplex-based, label-free, switch-on luminescent detection assay for Ag+ ions based on the exonuclease III-mediated digestion of C-Ag+-C DNA. (2014) (20)
- A novel dinuclear iridium(III) complex as a G-quadruplex-selective probe for the luminescent switch-on detection of transcription factor HIF-1α (2016) (20)
- Structure-based repurposing of FDA-approved drugs as inhibitors of NEDD8-activating enzyme. (2014) (20)
- A label-free G-quadruplex-based mercury detection assay employing the exonuclease III-mediated cleavage of T–Hg2+–T mismatched DNA (2015) (20)
- Oligosaccharide-marker approach for qualitative and quantitative analysis of specific polysaccharide in herb formula by ultra-high-performance liquid chromatography-quadrupole-time-of-flight mass spectrometry: Dendrobium officinale, a case study. (2019) (20)
- A Highly Selective and Non-Reaction Based Chemosensor for the Detection of Hg2+ Ions Using a Luminescent Iridium(III) Complex (2013) (20)
- A reaction-based luminescent switch-on sensor for the detection of OH- ions in simulated wastewater. (2017) (20)
- A Ruthenium(II) Complex Supported by Trithiacyclononane and Aromatic Diimine Ligand as Luminescent Switch-On Probe for Biomolecule Detection and Protein Staining (2014) (19)
- Discovery of a small-molecule inhibitor of STAT3 by ligand-based pharmacophore screening. (2015) (19)
- Label-free luminescent detection of LMP1 gene deletion using an intermolecular G-quadruplex-based switch-on probe. (2015) (19)
- A rhodium(III)-based inhibitor of autotaxin with antiproliferative activity. (2017) (19)
- Synthesis of highly substituted indene derivatives by Brønsted acid catalyzed Friedel–Crafts reaction of homoallylic alcohols (2014) (19)
- Development of a luminescent G-quadruplex-selective iridium(III) complex for the label-free detection of adenosine (2016) (19)
- A tumour microenvironment-responsive polymeric complex for targeted depletion of tumour-associated macrophages (TAMs). (2017) (19)
- Inhibition of the p53/hDM2 protein-protein interaction by cyclometallated iridium(III) compounds (2016) (19)
- Autophagic degradation of epidermal growth factor receptor in gefitinib-resistant lung cancer by celastrol. (2016) (19)
- Comprehensive quantitative analysis of Shuang-Huang-Lian oral liquid using UHPLC–Q-TOF-MS and HPLC-ELSD (2014) (19)
- Chemical Structure and Immunomodulating Activities of an α-Glucan Purified from Lobelia chinensis Lour (2016) (19)
- Luminescent Ruthenium(II) Complex Bearing Bipyridine and N-Heterocyclic Carbene-based C∧N∧C Pincer Ligand for Live-Cell Imaging of Endocytosis (2015) (18)
- UGT73F17, a new glycosyltransferase from Glycyrrhiza uralensis, catalyzes the regiospecific glycosylation of pentacyclic triterpenoids. (2018) (18)
- Mimicking Strategy for Protein–Protein Interaction Inhibitor Discovery by Virtual Screening (2019) (18)
- Metalated Chromene and Chromone Complexes: pH Switchable Metal-Carbon Bonding Interaction, Photo-triggerable Chromone Delivery Application, and Antioxidative Activity. (2018) (18)
- Long-lived iridium(III) complexes as luminescent probes for the detection of periodate in living cells (2019) (18)
- A rhodium(III) complex inhibits LPS-induced nitric oxide production and angiogenic activity in cellulo. (2014) (18)
- Detection of 3'→5' exonuclease activity using a metal-based luminescent switch-on probe. (2013) (17)
- A cyclometalated iridium(III) complex used as a conductor for the electrochemical sensing of IFN-γ (2017) (17)
- A Novel Tetradentate Ruthenium(II) Complex Containing Tris(2- Pyridylmethyl)amine (tpa) As An Inhibitor Of Beta-amyloid Fibrillation. (2015) (17)
- A label-free triplex-to-G-qadruplex molecular switch for sensitive fluorescent detection of acetamiprid. (2018) (17)
- Transition metal complexes as imaging or therapeutic agents for neurodegenerative diseases. (2020) (16)
- Silver Triflate Catalyzed Cyclopropyl Carbinol Rearrangement for Benzo[b]oxepine and 2H‐Chromene Synthesis (2015) (16)
- Application of metal–organic framework for the adsorption and detection of food contamination (2021) (16)
- Epigenetic modulation by inorganic metal complexes (2016) (16)
- G-quadruplex-based detection of glyphosate in complex biological systems by a time-resolved luminescent assay (2020) (15)
- Evaluation of Cinnamomum osmophloeum Kanehira Extracts on Tyrosinase Suppressor, Wound Repair Promoter, and Antioxidant (2015) (15)
- Label-Free Luminescent Oligonucleotide-Based Probes (2013) (15)
- Structure-based design of flavone derivatives as c-myc oncogene down-regulators. (2013) (15)
- A long-lived iridium(iii) chemosensor for the real-time detection of GHB. (2017) (15)
- A Label-Free Luminescent Switch-On Assay for ATP Using a G-Quadruplex-Selective Iridium(III) Complex (2013) (15)
- A 7-methoxybicoumarin derivative selectively inhibits BRD4 BD2 for anti-melanoma therapy. (2020) (15)
- Antagonizing STAT5B dimerization with an osmium complex (2016) (14)
- Iridium(III)-based chemosensors for the detection of metal ions. (2019) (14)
- Application of label-free techniques in microfluidic for biomolecules detection and circulating tumor cells analysis (2019) (14)
- A bioactive ligand-conjugated iridium(III) metal-based complex as a Keap1–Nrf2 protein-protein interaction inhibitor against acetaminophen-induced acute liver injury (2021) (14)
- A cyclometallated iridium(III) complex as a c-myc G-quadruplex stabilizer and down-regulator of c-myc oncogene expression. (2013) (14)
- Astragalus Polysaccharide RAP Selectively Attenuates Paclitaxel-Induced Cytotoxicity Toward RAW 264.7 Cells by Reversing Cell Cycle Arrest and Apoptosis (2019) (14)
- Current advancements in Aβ luminescent probes and inhibitors of Aβ aggregation. (2012) (13)
- A G-pentaplex-based assay for Cs(+) ions in aqueous solution using a luminescent Ir(III) complex. (2016) (13)
- A one-step strategy for ultra-fast and low-cost mass production of plastic membrane microfluidic chips. (2016) (13)
- A highly sensitive G-quadruplex-based luminescent switch-on probe for the detection of polymerase 3'-5' proofreading activity. (2013) (13)
- A long-lived ferrocene-conjugated iridium(III) complex for sensitive turn-on luminescence detection of traces of DMSO in water and human serum. (2017) (13)
- Iridium(iii) complexes as reaction based chemosensors for medical diagnostics. (2018) (13)
- A long-lifetime iridium(iii) complex for lysosome tracking with high specificity and a large Stokes shift. (2018) (13)
- Discovery of a tetrahydroisoquinoline-based CDK9-cyclin T1 protein–protein interaction inhibitor as an anti-proliferative and anti-migration agent against triple-negative breast cancer cells (2021) (12)
- An iridium(III) complex/G-quadruplex ensemble for detection of ochratoxin A based on long-lifetime luminescent. (2019) (12)
- A robust photoluminescence screening assay identifies uracil-DNA glycosylase inhibitors against prostate cancer† (2020) (12)
- An oligosaccharide-marker approach to quantify specific polysaccharides in herbal formula by LC-qTOF-MS: Danggui Buxue Tang, a case study. (2020) (12)
- A rapid and label-free DNA-based interference reduction nucleic acid amplification strategy for viral RNA detection. (2021) (12)
- Discovery of deoxyvasicinone derivatives as inhibitors of NEDD8-activating enzyme. (2015) (12)
- Antcamphorols A-K, Cytotoxic and ROS Scavenging Triterpenoids from Antrodia camphorata. (2019) (12)
- Bioactive Luminescent Transition-Metal Complexes for Biomedical Applications (2013) (12)
- Iridium-based probe for luminescent nitric oxide monitoring in live cells (2018) (11)
- Aurone derivatives as Vps34 inhibitors that modulate autophagy (2019) (11)
- Drug screening strategies using metal-based luminescent probes (2021) (11)
- A G-triplex luminescent switch-on probe for the detection of mung bean nuclease activity. (2015) (11)
- Recent advances in virtual screening for drug discovery. (2015) (11)
- Application of a DNA-based luminescence switch-on method for the detection of mercury(II) ions in water samples from Hong Kong (2012) (11)
- Recent progress and developments of iridium-based compounds as probes for environmental analytes. (2018) (11)
- Monitoring of DNA-protein interaction with single gold nanoparticles by localized scattering plasmon resonance spectroscopy. (2013) (11)
- Inhibition of TLR1/2 dimerization by enantiomers of metal complexes. (2016) (10)
- Interference of Quercetin on Astragalus Polysaccharide-Induced Macrophage Activation (2018) (10)
- Synthesis and Evaluation of Dibenzothiophene Analogues as Pin1 Inhibitors for Cervical Cancer Therapy (2019) (10)
- A luminescence switch-on assay for the detection of specific gene deletion using G-quadruplex DNA and silver nanoclusters (2017) (10)
- Luminescent Iridium(III) Complexes Supported by N-Heterocyclic Carbene-based C^C^C-Pincer Ligands and Aromatic Diimines (2015) (10)
- Recent Progress and Development of G-Quadruplex-Based Luminescent Assays for Ochratoxin A Detection (2020) (9)
- Selective Inhibition of Lysine‐Specific Demethylase 5A (KDM5A) Using a Rhodium(III) Complex for Triple‐Negative Breast Cancer Therapy (2018) (9)
- Rhodium(III)-Based Inhibitor of the JMJD3-H3K27me3 Interaction and Modulator of the Inflammatory Response. (2018) (9)
- Comprehensive Quantitative Analysis of 32 Chemical Ingredients of a Chinese Patented Drug Sanhuang Tablet (2017) (9)
- Ytterbium(III) triflate catalyzed annulation of propargylic 1,4-diols with aryl sulfonamides to give highly substituted pyrrole derivatives (2014) (9)
- A simple iridium(III) dimer as a switch-on luminescent chemosensor for carbon disulfide detection in water samples. (2019) (9)
- Akt downstream of NFκB, MAPKs and IRF3 pathway involved in macrophage activation induced by Astragalus polysaccharide RAP (2017) (9)
- Purified Astaxanthin from Haematococcus pluvialis Promotes Tissue Regeneration by Reducing Oxidative Stress and the Secretion of Collagen In Vitro and In Vivo (2020) (9)
- Carrageenan activates monocytes via type-specific binding with interleukin-8: an implication for design of immuno-active biomaterials. (2017) (9)
- Real-time detection of oxalyl chloride based on a long-lived iridium(iii) probe. (2017) (9)
- Luminescent and colorimetric strategies for the label-free DNA-based detection of enzyme activity. (2013) (8)
- Chemoselective detection of alkyl halides via an iridium(III) luminescent probe (2018) (8)
- A G-quadruplex-selective luminescent iridium(III) complex and its application by long lifetime. (2017) (8)
- Cell-derived artificial nanovesicle as a drug delivery system for malignant melanoma treatment (2022) (8)
- Luminescent detection of nicking endonuclease Nb.BsmI activity by using a G-quadruplex-selective iridium(III) complex in aqueous solution (2017) (8)
- Structure-Based Approaches Targeting Oncogene Promoter G-Quadruplexes (2013) (8)
- A G-quadruplex-based platform for the detection of Hg2+ ions using a luminescent iridium(III) complex (2014) (8)
- Low toxic fluorescent nanoprobe applicable for sensing pH changes in biological environment (2018) (7)
- Aliphatic Group-Tethered Iridium Complex as a Theranostic Agent against Malignant Melanoma Metastasis (2020) (7)
- Using two-phase solvent systems for sample pretreatment increases yield of counter-current chromatography: Anemarrhena asphodeloides saponins, a case study (2014) (7)
- Luminescent Strategies for Label-Free G-Quadruplex-Based Enzyme Activity Sensing. (2017) (7)
- In silico identification of natural product inhibitors of JAK2. (2015) (7)
- Engineered Amp C β-lactamase as a fluorescent screening tool for class C β-lactamase inhibitors. (2011) (6)
- Iminoiodane- and Brønsted Base-Mediated Cross Dehydrogenative Coupling of Cyclic Ethers with 1,3-Dicarbonyl Compounds (2015) (6)
- Luminescence approaches for the rapid detection of disease-related receptor proteins using transition metal-based probes. (2020) (6)
- Comprehensive quantitative analysis of Chinese patent drug YinHuang drop pill by ultra high-performance liquid chromatography quadrupole time of flight mass spectrometry. (2016) (6)
- Interfering with S100B-effector protein interactions for cancer therapy. (2020) (6)
- Polymerase chain reaction-based ultrasensitive detection of HBV DNA via G-quadruplex selective iridium(III) complex luminescent probe. (2021) (6)
- A review on common ingredients of periocular cosmetics and their hazards (2015) (6)
- Correction: Discovery of a Natural Product-Like c-myc G-Quadruplex DNA Groove-Binder by Molecular Docking (2012) (5)
- Interference Reduction Biosensing Strategy for Highly Sensitive microRNA Detection. (2022) (5)
- Ratiometric fluorescent detection of pesticide based on split aptamer and magnetic separation (2022) (4)
- Cytotoxic triterpenoids fromAntrodia camphorataas sensitizers of paclitaxel (2020) (4)
- Group 8–9 Metal-Based Luminescent Chemosensors for Protein Biomarker Detection (2018) (4)
- Recent advances in the managements of type 2 diabetes mellitus and natural hypoglycemic substances (2022) (4)
- Ubiquitination Regulators Discovered by Virtual Screening for the Treatment of Cancer (2021) (4)
- Luteolin exerted less inhibitory effect on macrophage activation induced by Astragalus polysaccharide than by lipopolysaccharide (2017) (3)
- Simultaneous blocking of the pan‐RAF and S100B pathways as a synergistic therapeutic strategy against malignant melanoma (2020) (3)
- A Long-Lived Phosphorescence Amplification System Integrated with Graphene Oxide and a Stable Split G-Quadruplex Protector as an Isothermal "Off-On" Biosensor for the HBV Gene. (2020) (3)
- Structure-guided discovery of a luminescent theranostic toolkit for living cancer cells and the imaging behavior effect† (2020) (3)
- Development of a NIR iridium(III) complex for self-calibrated and luminogenic detection of boron trifluoride. (2022) (3)
- Time-Resolved Luminescent High-Throughput Screening Platform for Lysosomotropic Compounds in Living Cells. (2020) (3)
- Biological Applications of Supramolecular Coordination Complexes (2017) (3)
- Cover Picture: Cyclometalated Platinum(II) Complexes as Highly Sensitive Luminescent Switch‐On Probes for Practical Application in Protein Staining and Cell Imaging (Chem. Eur. J. 15/2009) (2009) (2)
- Editorial for "Recent advances in DNA-based biosensor". (2013) (2)
- Peptide‐Conjugated Long‐Lived Theranostic Imaging for Targeting GRPr in Cancer and Immune Cells (2020) (2)
- Pharmacophore modeling for the identification of small-molecule inhibitors of TACE. (2015) (2)
- Recent advances in the discovery and development of protein- protein interaction modulators by virtual screening (2015) (2)
- Characterization of His-tagged Rat Uroporphyrinogen III Synthase Wild-Type and Variant Enzymes (2007) (2)
- Hit identification of IKKβ natural product inhibitor (2013) (1)
- Brønsted Base-Mediated Aziridination of 2-Alkyl-Substituted-1,3-Dicarbonyl Compounds and 2-Acyl-Substituted-1,4-Dicarbonyl Compounds by Iminoiodanes (2017) (1)
- Gold‐Catalyzed Cycloisomerization and Diels—Alder Reaction of 1,4,9‐Dienyne Esters to 3a,6‐Methanoisoindole Esters with Pro‐Inflammatory Cytokine Antagonist Activity. (2015) (1)
- Correction: Inhibition of TLR1/2 dimerization by enantiomers of metal complexes. (2017) (1)
- Special Topic: DNA-Based Biosensors (2022) (1)
- Ytterbium(III) Triflate Catalyzed Annulation of Propargylic 1,4-Diols with Aryl Sulfonamides to Give Highly Substituted Pyrrole Derivatives. (2015) (1)
- Correction: Virtual screening and optimization of Type II inhibitors of JAK2 from a natural product library. (2015) (1)
- Correction to: The design and development of covalent protein-protein interaction inhibitors for cancer treatment (2020) (1)
- CTnI diagnosis in myocardial infarction using G-quadruplex selective Ir(Ⅲ) complex as effective electrochemiluminescence probe. (2022) (1)
- A portable oligonucleotide-based microfluidic device for the detection of VEGF165 in a three-step suspended-droplet mode. (2019) (0)
- Luminescent turn-on detection of Hg(II) via the quenching of an iridium(III) complex by Hg(II)-mediated silver nanoparticles (2017) (0)
- Future Frontiers in Small Molecule Inhibitors of Protein-Protein Interactions (2013) (0)
- Inside Cover: Peptide‐Conjugated Long‐Lived Theranostic Imaging for Targeting GRPr in Cancer and Immune Cells (Angew. Chem. Int. Ed. 41/2020) (2020) (0)
- Luminescent cyclometalated platinum (II) complexes in DNA binding studies and their cytotoxicities against carcinoma cell lines (2003) (0)
- Title A natural product-like JAK 2 / STAT 3 inhibitor induces apoptosisof malignant melanoma cells (2017) (0)
- A labile iridium(III) complex-based luminogenic probe for the ratiometric detection of dithiocarbamate compounds in living system (2022) (0)
- Inside front cover. (2016) (0)
- G-quadruplex-selective iridium(III) complex as a novel electrochemiluminescence probe for switch-on assay of double-stranded DNA (2022) (0)
- Future Frontiers in Diversity-Oriented Synthesis (2013) (0)
- A time-resolved ratiometric luminescent anthrax biomarker nanosensor based on an Ir(III) complex-doped coordination polymer network. (2022) (0)
- Antagonizing STAT3 dimerization with a rhodium(III) complex (2015) (0)
- Turn-on Luminescent Probe for Hydrogen Peroxide Sensing and Imaging in Living Cells based on an Iridium(III) Complex–Silver Nanoparticle Platform (2017) (0)
- Interference reduction isothermal nucleic acid amplification strategy for COVID-19 variant detection (2022) (0)
- Inside Back Cover: Selective Inhibition of Lysine‐Specific Demethylase 5A (KDM5A) Using a Rhodium(III) Complex for Triple‐Negative Breast Cancer Therapy (Angew. Chem. Int. Ed. 40/2018) (2018) (0)
- Affinity-Based Luminescent Iridium(III) Complexes for the Detection of Disease-Related Proteins (2022) (0)
- Hit identification of anthraquinone based molecules as c-myc G-quadruplex inducers/stabilizers via in silico structural similarity approach (2011) (0)
- Oligonucleotide‐Based Luminescent Detection of Metal Ions. (2011) (0)
- Innentitelbild: Peptide‐Conjugated Long‐Lived Theranostic Imaging for Targeting GRPr in Cancer and Immune Cells (Angew. Chem. 41/2020) (2020) (0)
- A label-free oligonucleotide-based “OR” logic gate using an Ir(III) complex as a luminescent switch-on probe (2015) (0)
- Title Luminescent detection of DNA-binding proteins (2012) (0)
- Innenrücktitelbild: Selective Inhibition of Lysine‐Specific Demethylase 5A (KDM5A) Using a Rhodium(III) Complex for Triple‐Negative Breast Cancer Therapy (Angew. Chem. 40/2018) (2018) (0)
- Development of an orally bioavailable selective inhibitor of the menin-MLL (2022) (0)
- Recent Development of c-myc G-Quadruplex Ligands (2011) (0)
- Rücktitelbild: Antagonizing STAT3 Dimerization with a Rhodium(III) Complex (Angew. Chem. 35/2014) (2014) (0)
- Iridium-based probe for luminescent nitric oxide monitoring in live cells (2018) (0)
- A Cell-Impermeable Luminogenic Probe for Near-Infrared Imaging of Prostate-Specific Membrane Antigen in Prostate Cancer Microenvironments (2022) (0)
- Cover Picture: Stable Anticancer Gold(III)–Porphyrin Complexes: Effects of Porphyrin Structure (Chem. Eur. J. 10/2010) (2010) (0)
- SURVEY AND SUMMARY Luminescent detection of DNA-binding proteins (2012) (0)
- Back Cover: Antagonizing STAT3 Dimerization with a Rhodium(III) Complex (Angew. Chem. Int. Ed. 35/2014) (2014) (0)
- Front cover. (2018) (0)
- Drug Repositioning by Structure‐Based Virtual Screening (2013) (0)
- Synthesis of Highly Substituted Indene Derivatives by Broensted Acid Catalyzed Friedel—Crafts Reaction of Homoallylic Alcohols. (2014) (0)
- Silver Triflate Catalyzed Cyclopropyl Carbinol Rearrangement for Benzo[b]oxepine and 2H-Chromene Synthesis. (2015) (0)
- Development of a Sensitive Luminescent Probe to Uncover New BRD4 Inhibitors in Living Cells (2023) (0)
- Editorial: Small molecule therapeutics for Alzheimer's disease. (2015) (0)
- Front cover. (2016) (0)
- Natural products as inhibitors of the ubiquitin-/ubiquitin-like protein-proteasome pathway (2012) (0)
- G-quadruplex DNA for the construction of sensing platforms (2015) (0)
- Structure-based discovery of natural product-like protein inhibitors (2014) (0)
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