Dino Moras
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French biochemist and chemist
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Dino Morasbiology Degrees
Biology
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Biochemistry
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#681
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Chemistry Biology
Dino Moras's Degrees
- PhD Biochemistry University of Strasbourg
- Doctorate Chemistry University of Strasbourg
Why Is Dino Moras Influential?
(Suggest an Edit or Addition)According to Wikipedia, Dino Moras, born on 23 November 1944, is a French biochemist, research director at the CNRS and co-director of the Institute of Genetics and Molecular and Cellular Biology in Illkirch-Graffenstaden until 2010.
Dino Moras's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Chemical and biological evolution of a nucleotide-binding protein (1974) (1357)
- Partition of tRNA synthetases into two classes based on mutually exclusive sets of sequence motifs (1990) (1211)
- Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-α (1995) (1036)
- A canonical structure for the ligand-binding domain of nuclear receptors (1996) (955)
- Crystal structure of the RAR-γ ligand-binding domain bound to all-trans retinoic acid (1995) (920)
- The nuclear receptor ligand-binding domain: structure and function. (1998) (853)
- The crystal structure of the nuclear receptor for vitamin D bound to its natural ligand. (2000) (731)
- Spontaneous assembly of double-stranded helicates from oligobipyridine ligands and copper(I) cations: structure of an inorganic double helix. (1987) (605)
- An attempt to unify the structure of polymerases. (1990) (592)
- Class II aminoacyl transfer RNA synthetases: crystal structure of yeast aspartyl-tRNA synthetase complexed with tRNA(Asp) (1991) (560)
- Correlation between segmental mobility and the location of antigenic determinants in proteins (1984) (538)
- Transmembrane Signaling across the Ligand-Gated FhuA Receptor Crystal Structures of Free and Ferrichrome-Bound States Reveal Allosteric Changes (1998) (527)
- Crystallographic refinement of yeast aspartic acid transfer RNA. (1985) (399)
- Crystal structure of a heterodimeric complex of RAR and RXR ligand-binding domains. (2000) (388)
- An operational RNA code for amino acids and possible relationship to genetic code. (1993) (369)
- Comparative analysis of ribosomal proteins in complete genomes: an example of reductive evolution at the domain scale. (2002) (348)
- Studies of asymmetry in the three-dimensional structure of lobster D-glyceraldehyde-3-phosphate dehydrogenase. (1977) (303)
- Structural and functional considerations of the aminoacylation reaction. (1997) (294)
- Crystal structure of the human RXRα ligand‐binding domain bound to its natural ligand: 9‐cis retinoic acid (2000) (293)
- The Structure of Threonyl-tRNA Synthetase-tRNAThr Complex Enlightens Its Repressor Activity and Reveals an Essential Zinc Ion in the Active Site (1999) (288)
- A unique PPARgamma ligand with potent insulin-sensitizing yet weak adipogenic activity. (2001) (283)
- Structural and functional evidence for ligand-independent transcriptional activation by the estrogen-related receptor 3. (2002) (275)
- The NF-YB/NF-YC Structure Gives Insight into DNA Binding and Transcription Regulation by CCAAT Factor NF-Y* (2003) (267)
- Ultrahigh resolution drug design I: Details of interactions in human aldose reductase–inhibitor complex at 0.66 Å (2004) (264)
- Structural basis for messenger RNA movement on the ribosome (2006) (261)
- Crystal structure of yeast tRNAAsp (1980) (246)
- Structural studies on nuclear receptors (2000) (243)
- Construction of a set Gateway-based destination vectors for high-throughput cloning and expression screening in Escherichia coli. (2005) (242)
- Yeast tRNAAsp recognition by its cognate class II aminoacyl-tRNA synthetase (1993) (240)
- Structural adaptability in the ligand-binding pocket of the ecdysone hormone receptor (2003) (230)
- Translationally controlled tumor protein is a target of tumor reversion. (2004) (225)
- Three-dimensional structure of D-glyceraldehyde-3-phosphate dehydrogenase. (1974) (218)
- Sequence-Specific Transcription Factor NF-Y Displays Histone-like DNA Binding and H2B-like Ubiquitination (2013) (215)
- The Molecular Basis of Vitamin D Receptor and β-Catenin Crossregulation (2006) (211)
- Crystal structure of Aeromonas proteolytica aminopeptidase: a prototypical member of the co-catalytic zinc enzyme family. (1994) (210)
- A 'specificity' pocket inferred from the crystal structures of the complexes of aldose reductase with the pharmaceutically important inhibitors tolrestat and sorbinil. (1997) (209)
- Molecular Structure of Human TFIIH (2000) (201)
- Translationally controlled tumor protein acts as a guanine nucleotide dissociation inhibitor on the translation elongation factor eEF1A (2003) (201)
- Binding of ligands and activation of transcription by nuclear receptors. (2001) (199)
- Crystal structures of the vitamin D receptor complexed to superagonist 20-epi ligands (2001) (198)
- A transcriptional silencing domain in DAX-1 whose mutation causes adrenal hypoplasia congenita. (1997) (198)
- DNA gyrase interaction with coumarin-based inhibitors: the role of the hydroxybenzoate isopentenyl moiety and the 5'-methyl group of the noviose. (2002) (197)
- Crystal structure of the RAR-gamma ligand-binding domain bound to all-trans retinoic acid. (1995) (196)
- TCTP protects from apoptotic cell death by antagonizing bax function (2008) (192)
- Structural and functional relationships between aminoacyl-tRNA synthetases. (1992) (185)
- Transfer RNA–Mediated Editing in Threonyl-tRNA Synthetase The Class II Solution to the Double Discrimination Problem (2000) (177)
- Structure of the full human RXR/VDR nuclear receptor heterodimer complex with its DR3 target DNA (2012) (176)
- Common architecture of nuclear receptor heterodimers on DNA direct repeat elements with different spacings (2011) (170)
- Crystal Structure of the Ligand-binding Domain of the Ultraspiracle Protein USP, the Ortholog of Retinoid X Receptors in Insects* (2001) (170)
- Novel NADPH-binding domain revealed by the crystal structure of aldose reductase (1992) (169)
- Antagonism in the human mineralocorticoid receptor (1998) (167)
- Cysteine mapping in conformationally distinct kinase nucleotide binding sites: application to the design of selective covalent inhibitors. (2011) (165)
- Cisplatin‐ and UV‐damaged DNA lure the basal transcription factor TFIID/TBP (1997) (163)
- Dimerization of Escherichia coli DNA-gyrase B Provides a Structural Mechanism for Activating the ATPase Catalytic Center* (2000) (163)
- Synthesis of aspartyl‐tRNAAsp in Escherichia coli—a snapshot of the second step (1999) (153)
- Molecular recognition of agonist ligands by RXRs. (2002) (153)
- tRNA aminoacylation by arginyl‐tRNA synthetase: induced conformations during substrates binding (2000) (152)
- Identification of an alternative ligand-binding pocket in the nuclear vitamin D receptor and its functional importance in 1alpha,25(OH)2-vitamin D3 signaling. (2004) (150)
- All-trans retinoic acid is a ligand for the orphan nuclear receptor RORβ (2003) (150)
- Restrained refinement of two crystalline forms of yeast aspartic acid and phenylalanine transfer RNA crystals. (1987) (147)
- Human TAFII28 and TAFII18 Interact through a Histone Fold Encoded by Atypical Evolutionary Conserved Motifs Also Found in the SPT3 Family (1998) (146)
- The aminoacyl‐tRNA synthetase family: Modules at work (1993) (145)
- Functional insights from structures of coactivator‐associated arginine methyltransferase 1 domains (2007) (140)
- Estrogen receptor transcription and transactivation: Structure-function relationship in DNA- and ligand-binding domains of estrogen receptors (2000) (133)
- A mutation mimicking ligand‐induced conformational change yields a constitutive RXR that senses allosteric effects in heterodimers (1997) (132)
- Crystal Structure of a Mutant hERα Ligand-binding Domain Reveals Key Structural Features for the Mechanism of Partial Agonism* (2001) (132)
- D-glyceraldehyde-3-phosphate dehydrogenase: three-dimensional structure and evolutionary significance. (1973) (131)
- Zinc ion mediated amino acid discrimination by threonyl-tRNA synthetase (2000) (131)
- Crystallographic structure of an RNA helix: [U(UA)6A]2. (1989) (130)
- Conformational adaptation of agonists to the human nuclear receptor RARγ (1998) (128)
- The active site of yeast aspartyl‐tRNA synthetase: structural and functional aspects of the aminoacylation reaction. (1994) (127)
- Crystal structure of aspartyl‐tRNA synthetase from Pyrococcus kodakaraensis KOD: archaeon specificity and catalytic mechanism of adenylate formation (1998) (127)
- Retinoic Acid Receptors Recognize the Mouse Genome through Binding Elements with Diverse Spacing and Topology* (2012) (126)
- Crystal structure of histidyl‐tRNA synthetase from Escherichia coli complexed with histidyl‐adenylate. (1995) (125)
- Co-expression of protein complexes in prokaryotic and eukaryotic hosts: experimental procedures, database tracking and case studies. (2006) (124)
- Structural Basis for the Deactivation of the Estrogen-related Receptor γ by Diethylstilbestrol or 4-Hydroxytamoxifen and Determinants of Selectivity* (2004) (124)
- Structural Basis for the Cell-specific Activities of the NGFI-B and the Nurr1 Ligand-binding Domain* (2005) (123)
- Structural and functional characterization of a novel type of ligand‐independent RXR‐USP receptor (2007) (123)
- The molecular basis of vitamin D receptor and beta-catenin crossregulation. (2006) (118)
- Specific Recognition of Androgens by Their Nuclear Receptor (2000) (118)
- X‐ray structure of the orphan nuclear receptor RORβ ligand‐binding domain in the active conformation (2001) (115)
- Binding of Estrogenic Compounds to Recombinant Estrogen Receptor-α: Application to Environmental Analysis (2004) (114)
- LIGAND-BINDING DOMAIN OF THE HUMAN NUCLEAR RECEPTOR RXR-ALPHA (1996) (114)
- Structure determination of crystalline lobster D-glyceraldehyde-3-phosphate dehydrogenase. (1974) (113)
- The TBP-like factor: an alternative transcription factor in metazoa? (1999) (111)
- Achieving error-free translation; the mechanism of proofreading of threonyl-tRNA synthetase at atomic resolution. (2004) (108)
- Structural basis for isotype selectivity of the human retinoic acid nuclear receptor. (2000) (108)
- Crystal structure of glycyl‐tRNA synthetase from Thermus thermophilus. (1995) (107)
- Yeast tRNAAsp tertiary structure in solution and areas of interaction of the tRNA with aspartyl-tRNA synthetase. A comparative study of the yeast phenylalanine system by phosphate alkylation experiments with ethylnitrosourea. (1985) (106)
- Ligand–protein interactions in nuclear receptors of hormones (2000) (104)
- Translational Operator of mRNA on the Ribosome: How Repressor Proteins Exclude Ribosome Binding (2005) (103)
- Coordinated amino acid changes in homologous protein families. (1988) (103)
- The active site of yeast aspartyl-tRNA synthetase: structural and functional aspects of the aminoacylation reaction. (1994) (102)
- Quantitative cell-based reporter gene assays using droplet-based microfluidics. (2010) (100)
- Crystal structure of cleaved bovine antithrombin III at 3.2 A resolution. (1993) (100)
- Crystal structure of a prokaryotic aspartyl tRNA‐synthetase. (1994) (97)
- The structure of the Aeromonas proteolytica aminopeptidase complexed with a hydroxamate inhibitor. Involvement in catalysis of Glu151 and two zinc ions of the co-catalytic unit. (1996) (97)
- Structural basis for HIV‐1 DNA integration in the human genome, role of the LEDGF/P75 cofactor (2009) (96)
- The Human TFIID Components TAFII135 and TAFII20 and the Yeast SAGA Components ADA1 and TAFII68 Heterodimerize to Form Histone-Like Pairs (2000) (95)
- L‐Arginine recognition by yeast arginyl‐tRNA synthetase (1998) (94)
- Binding of aldose reductase inhibitors: correlation of crystallographic and mass spectrometric studies (1999) (93)
- Effects of ligand binding on the association properties and conformation in solution of retinoic acid receptors RXR and RAR. (2001) (93)
- An Open Conformation of the Thermus thermophilusGyrase B ATP-binding Domain* (2002) (93)
- The first step of aminoacylation at the atomic level in histidyl-tRNA synthetase. (1997) (91)
- X-ray structure at 1.55 A of toxin gamma, a cardiotoxin from Naja nigricollis venom. Crystal packing reveals a model for insertion into membranes. (1994) (90)
- Overexpression, purification, and crystal structure of native ER alpha LBD. (2001) (89)
- The structure of cyclin H: common mode of kinase activation and specific features (1997) (89)
- Unusual helical packing in crystals of DNA bearing a mutation hot spot (1989) (88)
- Phosphorylation of a conserved serine in the deoxyribonucleic acid binding domain of nuclear receptors alters intracellular localization. (2007) (88)
- The structure of an AspRS—tRNAAsp complex reveals a tRNA‐dependent control mechanism (2001) (88)
- Structural basis for engineering of retinoic acid receptor isotype-selective agonists and antagonists. (1999) (86)
- Crystal structure of the stromelysin-3 (MMP-11) catalytic domain complexed with a phosphinic inhibitor mimicking the transition-state. (2001) (85)
- Base-pairing shift in the major groove of (CA)n tracts by B-DNA crystal structures (1991) (83)
- Phosphorylation by PKA potentiates retinoic acid receptor alpha activity by means of increasing interaction with and phosphorylation by cyclin H/cdk7. (2006) (82)
- Signature of the oligomeric behaviour of nuclear receptors at the sequence and structural level (2004) (80)
- 3-D graphics modelling of the tRNA-like 3'-end of turnip yellow mosaic virus RNA: structural and functional implications. (1987) (80)
- The 2.0 A crystal structure of Thermus thermophilus methionyl-tRNA synthetase reveals two RNA-binding modules. (2000) (80)
- NF-Y Recruitment of TFIID, Multiple Interactions with Histone Fold TAFIIs* (2002) (78)
- How to finger DNA (1995) (77)
- Probing a water channel near the A-ring of receptor-bound 1α,25-dihydroxyvitamin D3 with selected 2α-substituted analogues (2006) (77)
- The role of purification in the crystallization of proteins and nucleic acids (1986) (77)
- 1α,25(OH)2-3-Epi-Vitamin D3, a Natural Physiological Metabolite of Vitamin D3: Its Synthesis, Biological Activity and Crystal Structure with Its Receptor (2011) (76)
- Adaptability of the Vitamin D nuclear receptor to the synthetic ligand Gemini: Remodelling the LBP with one side chain rotation (2007) (75)
- C-H...O hydrogen bonds in the nuclear receptor RARgamma--a potential tool for drug selectivity. (2002) (75)
- The structure of Staphylococcus aureus epidermolytic toxin A, an atypic serine protease, at 1.7 A resolution. (1997) (74)
- Dissecting the interaction network of multiprotein complexes by pairwise coexpression of subunits in E. coli. (2001) (74)
- Recognition of tRNAs by aminoacyl‐tRNA synthetases (1993) (73)
- Functional and structural characterization of the insertion region in the ligand binding domain of the vitamin D nuclear receptor. (2001) (73)
- Structural basis for a molecular allosteric control mechanism of cofactor binding to nuclear receptors (2012) (72)
- Structural basis of translational control by Escherichia coli threonyl tRNA synthetase (2002) (70)
- Synthesis and recognition of aspartyl-adenylate by Thermus thermophilus aspartyl-tRNA synthetase. (1994) (69)
- All-trans retinoic acid is a ligand for the orphan nuclear receptor ROR beta. (2003) (69)
- Critical Role of Desolvation in the Binding of 20-Hydroxyecdysone to the Ecdysone Receptor* (2007) (67)
- Defining and characterizing protein surface using alpha shapes (2009) (67)
- Specific amino acid recognition by aspartyl-tRNA synthetase studied by free energy simulations. (1998) (66)
- Superagonistic Action of 14-epi-Analogs of 1,25-Dihydroxyvitamin D Explained by Vitamin D Receptor-Coactivator Interaction (2005) (66)
- Solvation of the left-handed hexamer d(5BrC-G-5BrC-G-5 BrC-G) in crystals grown at two temperatures. (1986) (66)
- Crystal Structure of a Subcomplex of Human Transcription Factor TFIID Formed by TATA Binding Protein-associated Factors hTAF4 (hTAFII135) and hTAF12 (hTAFII20)* (2002) (66)
- Antithrombin III: structural and functional aspects. (1990) (66)
- High resolution structure of the RNA duplex [U(U-A)6A]2 (1988) (66)
- Enantiomer discrimination illustrated by high-resolution crystal structures of the human nuclear receptor hRARgamma. (2000) (65)
- Crystallographic computing 5: from chemistry to biology: papers presented at the International School in crystallographic computing held at Bischenberg, France, 29 July -- 5 August 1990 (1992) (65)
- Retinoic acid receptor: a simulation analysis of retinoic acid binding and the resulting conformational changes. (1999) (65)
- p52 Mediates XPB Function within the Transcription/Repair Factor TFIIH* 210 (2002) (65)
- The oxonium (H3O+) cation: molecular structure of an oxonium-macrocyclic polyether complex (1982) (64)
- A new model for 20‐hydroxyecdysone and dibenzoylhydrazine binding: A homology modeling and docking approach (2000) (64)
- Crystal structure of the V-region of Streptococcus mutans antigen I/II at 2.4 A resolution suggests a sugar preformed binding site. (2002) (64)
- Cardiotoxin VII4 from Naja mossambica mossambica. The refined crystal structure. (1990) (63)
- Crystal structure of the human RXRalpha ligand-binding domain bound to its natural ligand: 9-cis retinoic acid. (2000) (63)
- The “Phantom Effect” of the Rexinoid LG100754: Structural and Functional Insights (2010) (63)
- The free yeast aspartyl-tRNA synthetase differs from the tRNA(Asp)-complexed enzyme by structural changes in the catalytic site, hinge region, and anticodon-binding domain. (2000) (62)
- Comparison of the tertiary structure of yeast tRNA(Asp) and tRNA(Phe) in solution. Chemical modification study of the bases. (1987) (59)
- Structure-activity relationship of nuclear receptor-ligand interactions. (2003) (59)
- Glycyl-tRNA synthetase uses a negatively charged pit for specific recognition and activation of glycine. (1999) (58)
- Three-dimensional models of estrogen receptor ligand binding domain complexes, based on related crystal structures and mutational and structure-activity relationship data. (1998) (58)
- Hydration and recognition of methylated CpG steps in DNA (1998) (58)
- Crucial role of the H11-H12 loop in stabilizing the active conformation of the human mineralocorticoid receptor. (2000) (57)
- Interactions of yeast valyl-tRNA synthetase with RNAs and conformational changes of the enzyme. (1979) (56)
- Solution structure of a tRNA with a large variable region: yeast tRNASer. (1989) (56)
- Characterization of the DNA-Binding and Dimerization Properties of the Nuclear Orphan Receptor Germ Cell Nuclear Factor (1999) (56)
- DNA self‐fitting: the double helix directs the geometry of its supramolecular assembly. (1994) (56)
- A set of baculovirus transfer vectors for screening of affinity tags and parallel expression strategies. (2009) (56)
- Crystallization of a tRNA . aminoacyl-tRNA synthetase complex. Characterization and first crystallographic data. (1983) (54)
- Structural analysis of nuclear receptors: From isolated domains to integral proteins (2012) (54)
- Anticodon-anticodon interaction induces conformational changes in tRNA: yeast tRNAAsp, a model for tRNA-mRNA recognition. (1986) (53)
- Groove-backbone interaction in B-DNA. Implication for DNA condensation and recombination. (1991) (52)
- Crystallography in Molecular Biology (1987) (51)
- Allosteric controls of nuclear receptor function in the regulation of transcription. (2013) (50)
- Role of dimerization in yeast aspartyl-tRNA synthetase and importance of the class II invariant proline. (1993) (50)
- Crystal structure of a snake venom cardiotoxin. (1987) (49)
- Crystallographic studies on the aspartyl-tRNA synthetase-tRNAAsp system from yeast. The crystalline aminoacyl-tRNA synthetase. (1980) (48)
- Structural investigation of the ligand binding domain of the zebrafish VDR in complexes with 1α,25(OH)2D3 and Gemini: purification, crystallization and preliminary X-ray diffraction analysis (2004) (48)
- Structure-based design of a superagonist ligand for the vitamin D nuclear receptor. (2008) (48)
- Preliminary X-ray investigation of 70 S ribosome crystals from Thermus thermophilus. (1989) (47)
- Sequence variability and structure of D-glyceraldehyde-3-phosphate dehydrogenase. (1975) (47)
- Conformational movements and cooperativity upon amino acid, ATP and tRNA binding in threonyl-tRNA synthetase. (2003) (47)
- Crystal structure of a polyfunctional macrocyclic K+ complex provides a solid-state model of a K+ channel (1982) (46)
- A high resolution diffracting crystal form of the complex between yeast tRNAAsp and aspartyl-tRNA synthetase. (1988) (45)
- Structural and evolutionary innovation of the heterodimerization interface between USP and the ecdysone receptor ECR in insects. (2009) (45)
- Using nondenaturing mass spectrometry to detect fortuitous ligands in orphan nuclear receptors (2003) (45)
- Raloxifene and ICI182,780 increase estrogen receptor-alpha association with a nuclear compartment via overlapping sets of hydrophobic amino acids in activation function 2 helix 12. (2007) (45)
- Origin of an ancient hormone/receptor couple revealed by resurrection of an ancestral estrogen (2017) (44)
- Cavities in macrobicyclic ligands and complexation selectivity. Crystal structures of two cryptates, |Na+ .cntnd. 221|.cntdot.SCN- and |K+ .cntnd. 221|.cntdot.SCN-2 (1978) (44)
- A global transcription cofactor bound to juxtaposed strands of unwound DNA (2006) (44)
- An intermediate step in the recognition of tRNA(Asp) by aspartyl-tRNA synthetase. (2000) (44)
- CHIRAL AND FUNCTIONALIZED FACE-DISCRIMINATED AND SIDE-DISCRIMINATED MACROCYCLIC POLYETHERS. SYNTHESES AND CRYSTAL STRUCTURES (1981) (44)
- Interaction between vitamin D receptor and vitamin D ligands: two-dimensional alanine scanning mutational analysis. (2003) (43)
- Superagonistic fluorinated vitamin D3 analogs stabilize helix 12 of the vitamin D receptor. (2008) (42)
- Insights into metazoan evolution from alvinella pompejana cDNAs (2010) (42)
- Formation of a catalytically active complex between tRNAAsp and aspartyl-tRNA synthetase from yeast in high concentrations of ammonium sulphate. (1982) (41)
- The fidelity of the translation of the genetic code. (2001) (41)
- Hydration of transfer RNA molecules: a crystallographic study. (1988) (40)
- Structure-based analysis of the ultraspiracle protein and docking studies of putative ligands (2002) (40)
- Yeast transfer RNAasp: a new high-resolution x-ray diffracting crystal form of a transfer RNA. (1977) (40)
- Estrogen receptor–ligand complexes measured by chip‐based nanoelectrospray mass spectrometry: An approach for the screening of endocrine disruptors (2007) (40)
- Conformational changes and dynamics of tRNAs: evidence from hydrolysis patterns. (1987) (40)
- Aspartyl tRNA-synthetase from Escherichia coli: flexibility and adaptability to the substrates. (2000) (39)
- Ligand-binding pocket of the ecdysone receptor. (2005) (39)
- Ligand binding domain of vitamin D receptors. (2006) (39)
- Crystallization of transfer ribonucleic acids. (1984) (38)
- A vitamin D receptor selectively activated by gemini analogs reveals ligand dependent and independent effects. (2015) (38)
- Structure-function relationships and crystal structures of the vitamin D receptor bound 2 alpha-methyl-(20S,23S)- and 2 alpha-methyl-(20S,23R)-epoxymethano-1 alpha,25-dihydroxyvitamin D3. (2010) (37)
- In Vivo Topoisomerase I Inhibition Attenuates the Expression of Hypoxia-Inducible Factor 1α Target Genes and Decreases Tumor Angiogenesis (2012) (37)
- The class II aminoacyl-tRNA synthetases and their active site: Evolutionary conservation of an ATP binding site (1995) (37)
- Purification, functional characterization, and crystallization of the ligand binding domain of the retinoid X receptor. (1995) (36)
- Loop stereochemistry and dynamics in transfer RNA. (1983) (36)
- Silicon Analogues of the RXR‐Selective Retinoid Agonist SR11237 (BMS649): Chemistry and Biology (2009) (36)
- Heterodimeric complex of RAR and RXR nuclear receptor ligand-binding domains: purification, crystallization, and preliminary X-ray diffraction analysis. (2000) (35)
- The contacts of yeast tRNA(Ser) with seryl-tRNA synthetase studied by footprinting experiments. (1990) (35)
- Solution Structure of the C-terminal Domain of TFIIH P44 Subunit Reveals a Novel Type of C4C4 Ring Domain Involved in Protein-Protein Interactions* (2005) (35)
- The crystal structure of human cyclin H (1996) (35)
- Communication between the ERRα Homodimer Interface and the PGC-1α Binding Surface via the Helix 8–9 Loop* (2008) (34)
- The Asymmetric Binding of PGC-1α to the ERRα and ERRγ Nuclear Receptor Homodimers Involves a Similar Recognition Mechanism (2013) (34)
- Residues in the ligand binding domain that confer progestin or glucocorticoid specificity and modulate the receptor transactivation capacity. (2000) (33)
- Structural Characterization of the Cysteine-rich Domain of TFIIH p44 Subunit* (2000) (33)
- Solution structure and self-association properties of the p8 TFIIH subunit responsible for trichothiodystrophy. (2007) (32)
- First steps towards effective methods in exploiting high-throughput technologies for the determination of human protein structures of high biomedical value. (2006) (32)
- MAO: a Multiple Alignment Ontology for nucleic acid and protein sequences (2005) (32)
- Aspartate identity of transfer RNAs. (1996) (31)
- TFIID TAF6-TAF9 Complex Formation Involves the HEAT Repeat-containing C-terminal Domain of TAF6 and Is Modulated by TAF5 Protein* (2012) (31)
- The Structure and Function of Ecdysone Receptors (2009) (31)
- Sequence, overproduction and crystallization of aspartyl‐tRNA synthetase from Thermus thermophilus (1993) (31)
- Effect of cytosine methylation on DNA-DNA recognition at CpG steps. (1997) (30)
- Structure and oligomeric state of human transcription factor TFIIE (2006) (30)
- Crystal structures of two barium cryptates (1971) (30)
- Silicon Analogues of the Retinoid Agonists TTNPB and 3‐Methyl‐TTNPB, Disila‐TTNPB and Disila‐3‐methyl‐TTNPB: Chemistry and Biology (2007) (30)
- A single amino acid mutation of ala-773 in the mineralocorticoid receptor confers agonist properties to 11beta-substituted spirolactones. (2000) (29)
- Crystal structure of the vitamin D nuclear receptor ligand binding domain in complex with a locked side chain analog of calcitriol. (2007) (29)
- The structure of human aldose reductase bound to the inhibitor IDD384. (2000) (29)
- Production of crystals of human aldose reductase with very high resolution diffraction. (1999) (29)
- The palindromic DNA-bound USP/EcR nuclear receptor adopts an asymmetric organization with allosteric domain positioning (2014) (28)
- Structural and Functional Insights into the Ligand-binding Domain of a Nonduplicated Retinoid X Nuclear Receptor from the Invertebrate Chordate Amphioxus* (2009) (28)
- Domain architecture of the p62 subunit from the human transcription/repair factor TFIIH deduced by limited proteolysis and mass spectrometry analysis. (2004) (28)
- Polyoxamacrobicyclic diamines. Structure of 4,7,13,16,21,24-hexaoxa-1,10-diazabicyclo[8.8.8]hexacosane and of its bisborohydride, C18H36N2O6·2BH3 (1976) (28)
- Self-fitting and self-modifying properties of the B-DNA molecule. (1995) (28)
- The structure of yeast tRNA(Asp). A model for tRNA interacting with messenger RNA. (1985) (28)
- Solvent distribution in crystals of B- and Z-oligomers. (1985) (28)
- Crystallization of DNA. (1992) (27)
- Structural Basis of Natural Promoter Recognition by the Retinoid X Nuclear Receptor (2015) (26)
- Structural basis for the accommodation of bis- and tris-aromatic derivatives in vitamin D nuclear receptor. (2012) (26)
- Structure-function study of gemini derivatives with two different side chains at C-20, Gemini-0072 and Gemini-0097. (2011) (26)
- Reconstruction of quaternary structure from X-ray scattering by equilibrium mixtures of biological macromolecules. (2013) (26)
- Cruciform structures and functions (1996) (26)
- Synthetically accessible non-secosteroidal hybrid molecules combining vitamin D receptor agonism and histone deacetylase inhibition. (2012) (25)
- Structural and Functional Role of INI1 and LEDGF in the HIV-1 Preintegration Complex (2013) (25)
- Large-scale expression and purification of the human vitamin D receptor and its ligand-binding domain for structural studies. (1999) (25)
- Overproduction and purification of native and queuine-lacking Escherichia coli tRNA(Asp). Role of the wobble base in tRNA(Asp) acylation. (1993) (24)
- Yeast tRNAAsp-aspartyl-tRNA synthetase: the crystalline complex. (1983) (24)
- Synergistic Transcriptional Activation by TATA-Binding Protein and hTAFII28 Requires Specific Amino Acids of the hTAFII28 Histone Fold (1999) (23)
- Structural aspects and evolutionary implications of the recognition between tRNAs and aminoacyl-tRNA synthetases. (1993) (23)
- Monitoring ligand-mediated nuclear receptor-coregulator interactions by noncovalent mass spectrometry. (2004) (23)
- Crystal structure, biochemical and genetic characterization of yeast and E. cuniculi TAF(II)5 N-terminal domain: implications for TFIID assembly. (2007) (22)
- Aminoacyl-tRNA synthetases: Current opinion in structural biology 1992, 2:138…-142 (1992) (22)
- Properties of polyglutamine expansion in vitro and in a cellular model for Huntington's disease. (1999) (22)
- Conformational flexibility of tRNA: structural changes in yeast tRNA(Asp) upon binding to aspartyl-tRNA synthetase. (1996) (22)
- Biochemical and NMR Mapping of the Interface between CREB-binding Protein and Ligand Binding Domains of Nuclear Receptor (2005) (22)
- Crystallization of the 43 kDa ATPase domain of Thermus thermophilus gyrase B in complex with novobiocin. (2002) (21)
- Rapid purification of the Aeromonas proteolytica aminopeptidase: crystallization and preliminary X-ray data. (1992) (21)
- Dynamic correlation networks in human peroxisome proliferator-activated receptor-γ nuclear receptor protein (2010) (21)
- RNA-Protein Interactions: Diverse modes of recognition (1995) (20)
- Solution Structures of PPARγ2/RXRα Complexes (2012) (20)
- Crucial Role of the HIGH-loop Lysine for the Catalytic Activity of Arginyl-tRNA Synthetase* (2001) (20)
- Crystallogenesis studies on yeast aspartyl-tRNA synthetase: use of phase diagram to improve crystal quality. (1999) (20)
- Monitoring ligand modulation of protein-protein interactions by mass spectrometry: estrogen receptor alpha-SRC1. (2008) (19)
- The active site of yeast aspartyl-tRNA synthetase (1993) (19)
- Active site mapping of yeast aspartyl-tRNA synthetase by in vivo selection of enzyme mutations lethal for cell growth. (1999) (19)
- Model of the catalytic mechanism of human aldose reductase based on quantum chemical calculations (2000) (18)
- Three‐dimensional structure of yeast tRNAAsp. I. Structure determination (1986) (18)
- Crystallization of aspartyl-tRNA synthetase-tRNA(Asp) complex from Escherichia coli and first crystallographic results. (1992) (18)
- Crystal structures of three alkali-metal complexes with a macrobicyclic ligand (1971) (18)
- Yeast aspartyl-tRNA synthetase: a structural view of the aminoacylation reaction. (1993) (18)
- Structural Genomics of Eukaryotic Targets at a Laboratory Scale (2005) (17)
- Crystallization and preliminary X-ray data of a phleomycin-binding protein from Streptoalloteichus hindustanus. (1989) (17)
- Protein–RNA interactions: Getting into the major groove (1996) (17)
- Macromolecular crystallography with synchrotron radiation: collection and processing of data from crystals with a very large unit cell (1984) (17)
- Formation and crystallization of Thermus thermophilus 70S ribosome/tRNA complexes (1991) (16)
- Expression of FLAG fusion proteins in insect cells: application to the multi-subunit transcription/DNA repair factor TFIIH. (2002) (16)
- Crystal structure of bovine antithrombin III (1990) (16)
- SM2PH‐db: an interactive system for the integrated analysis of phenotypic consequences of missense mutations in proteins involved in human genetic diseases (2010) (16)
- Design and synthesis of active vitamin D analogs (2010) (16)
- A neutron investigation of yeast valyl-tRNA synthetase interaction with tRNAs. (1977) (16)
- Nuclear receptors. How to finger DNA. (1995) (16)
- Crystallization of histidyl-tRNA synthetase from Escherichia coli. (1994) (16)
- Purification of the Human RARγ Ligand-Binding Domain and Crystallization of Its Complex with All-transRetinoic Acid (1997) (15)
- CRYSTAL STRUCTURE OF THE HUMAN RXR ALPHA LIGAND BINDING DOMAIN BOUND TO 9-CIS RETINOIC ACID (2000) (15)
- Crystal structure of hereditary vitamin D-resistant rickets—Associated mutant H305Q of vitamin D nuclear receptor bound to its natural ligand (2010) (15)
- Structural Insights into the Polyphyletic Origins of Glycyl tRNA Synthetases*♦ (2016) (15)
- Detection of nucleic acid-nuclear hormone receptor complexes with mass spectrometry (2010) (15)
- The ligand-binding domains of the three RXR-USP nuclear receptor types support distinct tissue and ligand specific hormonal responses in transgenic Drosophila. (2009) (14)
- Functional insights into the core-TFIIH from a comparative survey. (2013) (14)
- Characterization of crystal content by ESI-MS and MALDI-MS. (2000) (14)
- RIKEN aids international structural genomics efforts (2007) (14)
- Design, synthesis, evaluation, and structure of vitamin D analogues with furan side chains. (2012) (14)
- Novel 1α,25-Dihydroxyvitamin D3 Analogues with the Side Chain at C12 (2006) (14)
- Crystallization and preliminary crystallographic data for bovine antithrombin III. (1989) (14)
- Structural Basis for Ligand Activity in VDR (2011) (14)
- Two sisters and their cousin (1993) (14)
- Probing a water channel near the A-ring of receptor-bound 1 alpha,25-dihydroxyvitamin D3 with selected 2 alpha-substituted analogues. (2006) (14)
- Sequence of tRNA(Asp) from Thermus thermophilus HB8. (1993) (13)
- A eukaryotic XPB/ERCC3-like helicase in Mycobacterium leprae? (1997) (13)
- A comparison of inoculation methods to simplify recombinant protein expression screening in Escherichia coli. (2008) (13)
- Engineering an Mg2+ site to replace a structurally conserved arginine in the catalytic center of histidyl‐tRNA synthetase by computer experiments (1998) (13)
- M-ORBIS: Mapping of mOleculaR Binding sItes and Surfaces (2010) (13)
- The crystal structure of a rubidium “cryptate”[RbC18H36N2O6]SCN·H2O (1970) (13)
- Structure-function relationships in nuclear receptors: the facts. (2015) (13)
- Structural insights into transcription complexes. (2011) (12)
- Characterization of a thermosensitive Escherichia coli aspartyl-tRNA synthetase mutant (1997) (12)
- Etude structurale du dioxychlorure de phosphore-hexachlorodiétain(IV)-di-μ-dichlorophosphate. I. Structure cristalline (1969) (12)
- Biophysical characterization of an indolinone inhibitor in the ATP-binding site of DNA gyrase. (2006) (12)
- Purification and crystallization of the human RXRalpha ligand-binding domain-9-cisRA complex. (2001) (12)
- Synthesis, Structure, and Biological Activity of des‐Side Chain Analogues of 1α,25‐Dihydroxyvitamin D3 with Substituents at C18 (2011) (12)
- Two complementary enzymes for threonylation of tRNA in crenarchaeota: crystal structure of Aeropyrum pernix threonyl-tRNA synthetase lacking a cis-editing domain. (2009) (12)
- ATP-Bound Conformation of Topoisomerase IV: a Possible Target for Quinolones in Streptococcus pneumoniae (2003) (11)
- Cleaved thioredoxin fusion protein enables the crystallization of poorly soluble ERalpha in complex with synthetic ligands. (2008) (11)
- Proofreading in translation: Dynamics of the double-sieve model (2010) (11)
- Importance of the Sequence-Directed DNA Shape for Specific Binding Site Recognition by the Estrogen-Related Receptor (2017) (11)
- Erratum: A canonical structure for the ligand-binding domain of nuclear receptors (1996) (11)
- A revisited version of the apo structure of the ligand-binding domain of the human nuclear receptor retinoic X receptor α. (2019) (11)
- Expression, purification, crystallization and preliminary crystallographic study of isolated modules of the mouse coactivator-associated arginine methyltransferase 1. (2007) (11)
- Three-dimensional structure of phenylalanyl-transfer RNA synthetase from Thermus thermophilus HB8 at 0.6-nm resolution. (1992) (10)
- Studies on anticodon-anticodon interactions: hemi-protonation of cytosines induces self-pairing through the GCC anticodon of E. coli tRNA-Gly. (1986) (10)
- Crystal structure of yeast tRNAAsp: atomic coordinates. (1985) (10)
- Conformational change in yeast tRNAAsp (1984) (10)
- Structural role of a detergent molecule in retinoic acid nuclear receptor crystals. (2000) (10)
- Towards high-throughput identification of endocrine disrupting compounds with mass spectrometry. (2009) (10)
- Crystallisation of the glycyl-tRNA synthetase from Thermus thermophilus and initial crystallographic data. (1994) (10)
- Correlation between equi-partition of aminoacyl-tRNA synthetases and amino-acid biosynthesis pathways (2020) (9)
- Architecture of DNA Bound RAR heterodimers. (2014) (8)
- The dual role of CHAPS in the crystallization of stromelysin-3 catalytic domain. (2003) (8)
- CRYSTALLIZATION AND PRELIMINARY X-RAY ANALYSIS OF ESCHERICHIA COLI METHIONYL-TRNAFMET FORMYLTRANSFERASE (1996) (8)
- Protein-nucleic acid interactions. (1995) (8)
- Automated recombinant protein expression screening in Escherichia coli. (2008) (8)
- Molecular dynamics in tRNA. Crystallographic and Raman spectroscopic evidence (1986) (8)
- Three-dimensional structure of yeast tRNA Asp . I. Structure determination (1985) (7)
- Crystal structure of the V-region of Streptococcus mutans antigen I/II (2002) (7)
- Crystallization and preliminary X-ray study of pig lens aldose reductase. (1987) (7)
- A structural view of ligand binding to the retinoid receptors (1998) (7)
- Low-Resolution Phase Extension and Refinement by Maximum Entropy (1988) (7)
- Macrotricyclic and macropentacyclic ditopic receptor molecules: synthesis, crystal structure and substrate binding (1987) (7)
- A eucentric goniometer head sliding on an extended removable arc modified for use in cryocrystallography (1998) (7)
- Crystallization and preliminary X‐ray analysis of Escherichia coli methionyl–tRNA fMet formyltransferase (1996) (7)
- Overexpression , Purification , and Crystal Structure of Native ER a LBD (2001) (6)
- Crystallization of threonyl‐tRNA synthetase from Thermus thermophilus and preliminary crystallographic data (1995) (6)
- Crystallization and preliminary crystallographic analysis of human glycosylated haemoglobin. (2006) (6)
- Functional and structural analysis of the subunits of human transcription factor TFIID. (1998) (6)
- Crystallization and preliminary X-ray analysis ofEscherichia coli methionyl–tRNAfMet formyltransferase (1996) (6)
- Packing and molecular interactions in tRNA crystals (1988) (6)
- Aldose Reductase from Pig Lens (1995) (6)
- Getting into the major groove. Protein-RNA interactions. (1996) (6)
- Structure of full-length PPARgamma-RXRalpha: a snapshot of a functional complex? (2009) (6)
- Structure determination of aldose reductase: joys and traps of local symmetry averaging. (1993) (6)
- Structural basis for HIV-1 DNA integration in the human genome (2009) (6)
- Sequence analysis and modular organization of threonyl-tRNA synthetase from Thermus thermophilus and its interrelation with threonyl-tRNA synthetases of other origins. (2000) (5)
- The Aspartic Acid tRNA System: Recognition by a Class II Aminoacyl-tRNA Synthetase (1995) (5)
- Sequence of tRNAAsp from Thermus thermophilus HB8 (1993) (5)
- Aminoacyl-tRNA Synthetases: Partition into two Classes (1992) (5)
- Crystal structure of a vitamin D3 analog, ZK203278, showing dissociated profile. (2011) (5)
- A structural signature motif enlightens the origin and diversification of nuclear receptors (2020) (5)
- Reaction of Fe2(CO)9 with a dithiophosphinate: X-ray crystal structures of two complexes formed by selective cleavage of the thiophosphoryl bond (1979) (4)
- Analysis of recombinant phosphoprotein complexes with complementary mass spectrometry approaches. (2010) (4)
- Crystal structure of the Sec 4 p : Sec 2 p complex in the nucleotide exchanging intermediate state (2008) (4)
- Identification of Endocrine-Disrupting Compounds Using Nanoelectrospray Ionization Mass Spectrometry (2008) (4)
- Retinoid Receptors: Protein Structure, DNA Recognition and Structure-Function Relationships (2015) (4)
- Aminoacyl‐tRNA Synthetases (2009) (4)
- [Crystallization of the complex formed between yeast aspartyl tRNA and its specific aminoacyl tRNA synthetase]. (1980) (4)
- Crystallization of Escherichia coli aspartyl-tRNA synthetase in its free state and in a complex with yeast tRNA(Asp). (1996) (4)
- A revisited version of the apo structure of the ligand-binding domain of the human nuclear receptor RXR-ALPHA (2019) (4)
- Crystal Structure of Glycated Human Haemoglobin (2008) (4)
- Crystallization and preliminary X-ray crystallographic analysis of yeast arginyl-tRNA synthetase-yeast tRNAArg complexes. (2000) (4)
- Protein-nucleic acid interactions Editorial overview (1992) (4)
- Nonsteroidal ecdysone receptor agonists use a water channel for binding to the ecdysone receptor complex EcR/USP (2021) (4)
- Solution Conformation of tRNAs: Correlation with Crystal Structures (1983) (4)
- TFIID TAF 6-TAF 9 Complex Formation Involves the HEAT Repeat-containing C-terminal Domain of TAF 6 and Is Modulated by TAF 5 Protein * (2012) (3)
- Aminoacylation at the Atomic Level in Class IIa Aminoacyl-tRNA Synthetases (2000) (3)
- Genomic organization of the rat aspartyl-tRNA synthetase gene family: a single active gene and several retropseudogenes. (1996) (3)
- Crystals of Thermus thermophilus tRNAAsp complexed with its cognate aspartyl-tRNA synthetase have a solvent content of 75%. Comparison with other aminoacylation systems. (1998) (3)
- Crystallization and preliminary crystallographic studies of putative threonyl-tRNA synthetases from Aeropyrum pernix and Sulfolobus tokodaii. (2008) (3)
- Editorial overviewProtein-nucleic acid interactions (1993) (3)
- Structure of the hydrazinium complex of a tetracarboxy-18-crown-6 receptor molecule (1987) (3)
- The Versatile Transfer RNA Molecule: Crystallography of Yeast tRNAAsp (1983) (3)
- Structural Studies of Insect Nuclear Receptors (2004) (3)
- The structural biology and genomics platform in strasbourg: an overview. (2008) (3)
- Molecular determinants for agonist and antagonist binding to steroid nuclear receptors. (2001) (2)
- Absolute Configuration of Natural Methionine Sulfoximine (1986) (2)
- tRNA/Aminoacyl-tRNA Synthetase Interactions (1998) (2)
- A novel nuclear receptor subfamily enlightens the origin of heterodimerization (2022) (2)
- Preliminary crystallographic data for exfoliative toxin B from Staphylococcus aureus. (1984) (2)
- CRYSTAL STRUCTURE OF THE STROMELYSIN-3 (MMP-11) CATALYTIC DOMAIN COMPLEXED WITH A PHOSPHINIC INHIBITOR (2001) (2)
- Crystallization of E. coli aspartate β-semialdehyde dehydrogenase (1980) (2)
- 4.28 – Nuclear Hormone Receptors: Insights for Drug Design from Structure and Modeling (2007) (2)
- Novel 1alpha,25-dihydroxyvitamin D3 analogues with the side chain at C12. (2006) (2)
- GU Base Pairs and Variable Loop in Yeast tRNAAsp (1986) (2)
- CRYSTAL STRUCTURE OF THE NUCLEAR RECEPTOR FOR VITAMIN D COMPLEXED TO VITAMIN D (2000) (2)
- Design, Chemical synthesis, Functional characterization and Crystal structure of the sidechain analogue of 1,25-dihydroxyvitamin D3. (2011) (1)
- Crystal structure of the human VDR ligand binding domain bound to the natural metabolite 1alpha,25-dihydroxy-3-epi-vitamin D3 (2010) (1)
- Policies in structural genomics/structural proteomics: E. The international structural genomics organization: Policies for structural genomics (2008) (1)
- CHAPTER 15 – Vitamin D Nuclear Receptor Ligand-Binding Domain Crystal Structures (2005) (1)
- Crystal structure of the Stromelysin-3 complexed with a phosphinic inhibitor reveals that its S1′ pocket is a deep opened cavity (2000) (1)
- Crystal structure of the human RXR alpha ligand binding domain bound to a synthetic agonist compound and a coactivator peptide (2009) (1)
- Crystal structure of the ligand-binding domains of the heterodimer EcR/USP bound to the synthetic agonist BYI06830 (2003) (1)
- Crystal structure of yeast TAF5 N-terminal domain (2007) (1)
- CRYSTALLOGRAPHIC INVESTIGATION OF ANTITHROMBIN III. (1987) (1)
- CardiotoxinV4II fromNaja mossambica mossambica (1990) (1)
- Single‐crystal diffractometry: strategy for rapidly decaying poorly diffracting crystals (1985) (1)
- Expression, purification, and characterization of a new heterotetramer structure of leucyl-tRNA synthetase from Aquifex aeolicus in Escherichia coli. (2006) (1)
- Structural Analysis of Heterodimeric Nuclear Receptors (2015) (1)
- Zinc ion mediated amino acid recognition by threonyl-tRNA synthetase (2000) (1)
- RARbeta ligand-binding domain bound to an SRC-1 co-activator peptide: purification, crystallization and preliminary X-ray diffraction analysis. (2004) (1)
- Structure and Interactions of Ribosomal Components and Ligands (1986) (1)
- Crystal structure of di(phosphoryl trichloride)hexachloroditin(IV) di-µ-dichlorophosphate (1968) (1)
- The Cryo-EM structure of the palindromic DNA-bound USP-EcR nuclear receptor reveals an asymmetric organization with allosteric domain positioning (2014) (1)
- Human Aldose Reductase in complex with NADP+ and the inhibitor IDD594 at 0.66 Angstrom (2004) (1)
- Crystallization of Aldose Reductase leading to Single Wavelength (0.66 Å) and MAD (0.9 Å) subatomic resolution studies (2000) (1)
- Development of synthetically accessible non-secosteroidal hybrid molecules combining vitamin D receptor agonism and histone deacetylase inhibition (2012) (1)
- Ligand Selectivity by Nuclear Hormone Receptors (2000) (1)
- YEAST ARGINYL-TRNA SYNTHETASE (1999) (1)
- Expression of functional full-length hSRC-1 in eukaryotic cells using modified vaccinia virus Ankara and baculovirus. (2012) (1)
- A Single Amino Acid Mutation of Ala-773 in the Mineralocorticoid Receptor Confers Agonist Properties to 11 b -Substituted Spirolactones (2000) (1)
- Synthetases gain recognition (1990) (1)
- Crystal structure of the editing domain of threonyl-tRNA synthetase complexed with an analog of seryladenylate (2004) (1)
- AMINOACYL-tRNA SYNTHETASES: INTERACTIONS WITH THEIR LIGANDS (1980) (1)
- Polymerases. Two sisters and their cousin. (1993) (1)
- RARβ ligand‐binding domain bound to an SRC‐1 co‐activator peptide: purification, crystallization and preliminary X‐ray diffraction analysis (2004) (1)
- Crystal structure of the ecdysone receptor bound to BYI08346 (2010) (1)
- Anticodon-anticodon interactions in solution: studies with yeast tRNAAsp (1984) (1)
- Crystal Structure Of The Nuclear Receptor For Vitamin D Ligand Binding Domain Bound to KH1060 (2001) (1)
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- Crystal structure of VDR LBD in complex with 2alpha-methyl calcitriol (2006) (0)
- Crystal structure of 70S ribosome with thrS operator and tRNAs. Large subunit. The coordinates for the small subunit are in the pdb entry 1YL4. (2005) (0)
- WILD TYPE ESTROGEN NUCLEAR RECEPTOR LIGAND BINDING DOMAIN COMPLEXED WITH ESTRADIOL (2000) (0)
- Allosteric control of transcription regulation by nuclear receptors: An integrative structural biology approach (2017) (0)
- Side-chain fluorine atoms of non-steroidal vitamin D3 analogs stabilize helix 12 of vitamin D receptor (2009) (0)
- HISTIDYL-TRNA SYNTHETASE COMPLEXED WITH HISTIDINOL AND ATP (1997) (0)
- Structure of Staphylococcus aureus threonyl-tRNA synthetase complexed with ATP (2003) (0)
- Crystal structure of VDR H305Q mutant (2010) (0)
- Interactions of Transfer RNAs with their Biological Partners (1984) (0)
- Crystal structure of the wild type CP1 hydrolitic domain from Aquifex Aeolicus leucyl-trna (2010) (0)
- Crystal structure of aspartyl-tRNA synthetase from Thermus thermophilus complexed to tRNAasp from Escherichia coli (2000) (0)
- Structural Proteomics in Relation to Signaling Pathways (2008) (0)
- Transcription regulation by nuclear receptors: structure-function relationships (2000) (0)
- Communications affichées - Reproduction (2008) (0)
- BASE-PAIRING SHIFT IN A DODECAMER CONTAINING A (CA)N TRACT (1999) (0)
- tRNAAsp aspartyl-tRNA synthetase recognition (1993) (0)
- Crystal structure ofglycyl-tRNA synthetase from Thermusthermophilus (1995) (0)
- Crystal structure of VDR LBD complexed to 2alpha-propyl-calcitriol (2006) (0)
- The tRNAAsp-Aspartyl-tRNA Synthetase System from Yeast: Structural and Functional Studies (1985) (0)
- CARBOXY-TERMINAL DOMAIN OF HUMAN TFIIH P44 SUBUNIT (2000) (0)
- ALDOSE REDUCTASE COMPLEXED WITH TOLRESTAT INHIBITOR (1998) (0)
- PIG ALDOSE REDUCTASE COMPLEXED WITH SORBINIL (1998) (0)
- Crystal structure of the ligand binding domain of the Vitamin D nuclear receptor in complex with Gemini and a coactivator peptide (2007) (0)
- The 2.55 A crystal structure of the apo catalytic domain of coactivator-associated arginine methyl transferase I(CARM1:28-507, residues 28-146 and 479-507 not ordered) (2007) (0)
- Crystal structure of human translationally controlled tumour associated protein (2006) (0)
- GLYCYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS COMPLEXED WITH ATP (1999) (0)
- Electrostatic potential in aminoacylation by aspartyl-tRNAs synthetase. (1995) (0)
- The 2.2 A crystal structure of the catalytic domain of coactivator-associated arginine methyl transferase I(CARM1,142-478), in complex with S-adenosyl homocysteine (2007) (0)
- Crystal structure of VDR LBD in complex with 2alpha-(1-propoxy) calcitriol (2006) (0)
- Crystal structure of the 70S Thermus thermophilus ribosome with translocated and rotated Shine-Dalgarno Duplex. (2014) (0)
- Functional Structures of Class-I Aminoacyl-tRNA Synthetases (1999) (0)
- crystal structure of the ligand-binding domain of the estrogen-related receptor gamma in complex with diethylstilbestrol (2004) (0)
- Crystal Structure of E. coli 24kDa Domain in Complex with Clorobiocin (2002) (0)
- LIGAND-BINDING DOMAIN OF THE HUMAN RETINOIC ACID RECEPTOR GAMMA BOUND TO ALL-TRANS RETINOIC ACID (1997) (0)
- X-ray structure of the orphan nuclear receptor ERR3 ligand-binding domain in the constitutively active conformation (2003) (0)
- POLYOXAMACROBICYCLIC DIAMINES. STRUCTURE OF 4,7,13,16,21,24-HEXAOXA-1,10-DIAZABICYCLO(8.8.8)HEXACOSANE AND OF ITS BISBOROHYDRIDE, C18H36N2O6.2BH3 (1976) (0)
- Two threonyl-tRNA synthetases with complementary functions; crystal structure of ThrRS-1 (2008) (0)
- Structural basis of specific DNA recognition by the estrogen-related receptor ERR (2018) (0)
- Cloning, purification and crystallization of a Walker-type Pyrococcus abyssi ATPase family member. (2005) (0)
- Crystal structure of E. coli threonyl-tRNA synthetase interacting with the essential domain of its mRNA operator (2002) (0)
- The Molecular Basis of Vitamin D Receptor and β-Catenin Crossregulation (DOI: 10.1016/j.molcel.2006.01.037) (2006) (0)
- Crystal structure of the 70S Thermus thermophilus ribosome with translocated and rotated Shine-Dalgarno Duplex. This entry 2HGP contains 30S ribosomal subunit. The 50S ribosomal subunit can be found in PDB entry 2HGQ. (2006) (0)
- Crystal structure of a mixed agonist-bound RAR-alpha and antagonist-bound RXR-alpha heterodimer ligand binding domains (2010) (0)
- Macrotricyclic and Macropentacyclic Ditopic Receptor Molecules. Synthesis, Crystal Structure, and Substrate Binding. (1987) (0)
- CRYSTAL STRUCTURE OF THE SELF-FITTED B-DNA DECAMER D(CCGCCGGCGG) (1999) (0)
- Characterization of ligands for the orphan nuclear receptor RORbeta (2003) (0)
- The HIV-1 Pre-Integration Complex: Structural and Functional Role of INI1 and LEDGF, Cellular Cofactors of Viral Integrase (2012) (0)
- Yeast tRNA(ASP)-aspartyl-tRNA synthetase complex at 7 Ã resolution (1987) (0)
- Acknowledgement to Reviewers of Life in 2017 (2018) (0)
- Structural basis for the concerted integration of HIV-1 DNA in the human genome, role of the human cofactor LEDGF/p75 (2008) (0)
- Nuclear receptor superfamily: structural insights into function (2007) (0)
- Functional insights from structures of coactivator-associated arginine methyltransferase 1 domains (2008) (0)
- Uncoating of Mature HIV Capsids Driven by Reverse Transcription (2012) (0)
- Crystal Structure of the Human TAF4-TAF12 (TAFII135-TAFII20) Complex (2002) (0)
- A major leap toward the tertiary structure of large RNAs. (1997) (0)
- Crystal structure of the ligand-binding domains of the heterodimer EcR/USP bound to ponasterone A (2003) (0)
- Crystal structure of VDR ligand binding domain complexed to calcipotriol. (2004) (0)
- ASPARTYL TRNA SYNTHETASE FROM THERMUS THERMOPHILUS AT 2.4 A RESOLUTION (2000) (0)
- Design of highly selective covalent kinase inhibitors (2010) (0)
- The thrS messenger path on the ribosome (2005) (0)
- derived polypeptides nuclear calcitriol receptor, and their use particularly in the context of screening analogues of vitamin D (1999) (0)
- Solution structure of the p8 TFIIH subunit (2007) (0)
- Unliganded aspartyl-tRNA synthetase from thermococcus kodakarensis (2010) (0)
- Transfer RNA. Synthetases gain recognition. (1990) (0)
- The Structural Biology and Genomics Technology Platform at the IGBMC (2013) (0)
- CRYSTAL STRUCTURE OF THE ARGINYL-TRNA SYNTHETASE COMPLEXED WITH THE TRNA(ARG) AND L-ARG (2001) (0)
- Correlation Between Crystal and Solution Structures in tRNA. Yeast tRNAPhe and tRNAAsp the Models for Free and Messenger RNA Bound tRNAs (1986) (0)
- Sequence of tRNAAspfrom Thermus thermophilusHB8 (1993) (0)
- ISOTYPE SELECTIVITY OF THE HUMAN RETINOIC ACID NUCLEAR RECEPTOR HRAR: THE COMPLEX WITH THE RARBETA/GAMMA-SELECTIVE RETINOID CD564 (2000) (0)
- Nucleic Acids Research (2003) (0)
- Crystal structure of putative threonyl-tRNA synthetase ThrRS-1 from Aeropyrum pernix (2009) (0)
- CRYSTAL STRUCTURE OF A TRUNCATED FORM OF THREONYL-TRNA SYNTHETASE WITH THE LIGAND THREONINE (2000) (0)
- Crystal structure of the 70S Thermus thermophilus ribosome showing how the 16S 3'-end mimicks mRNA E and P codons. (2014) (0)
- The fi del ity of the trans la tion of the ge netic code (2001) (0)
- The crystal structure of a b dna dodecamer reveals a sequence dependent shift of the base pairing in the major groove (1991) (0)
- DROPLETBASED MICROFLUIDICS FOR QUANTITATIVE CELLBASED REPORTER GENE ASSAYS (2010) (0)
- Table of Contents (1995) (0)
- Crystal structure of zVDR L337H mutant-Gemini72 complex (2015) (0)
- Information transfer in proteins: combining crystallographic and genomic approaches (2000) (0)
- HISTIDYL-TRNA SYNTHETASE COMPLEXED WITH HISTIDYL-ADENYLATE (1997) (0)
- Heterodimerize to Form Histone-Like Pairs 68 II Components ADA1 and TAF 20 and the Yeast SAGA II and TAF 135 II The Human TFIID Components TAF (2014) (0)
- Crystal structure of RARb LBD homodimer in complex with TTNPB (2012) (0)
- Crystal Structure of the Human Transcription Cofactor PC4 in Complex with Single-Stranded DNA (2006) (0)
- Crystal structure of 70S ribosome with thrS operator and tRNAs. (2014) (0)
- CRYSTAL STRUCTURE OF A TRUNCATED FORM OF THREONYL-TRNA SYNTHETASE WITH A THREONYL ADENYLATE ANALOG (2000) (0)
- Crystal structure of the editing domain of threonyl-tRNA synthetase (2004) (0)
- Controlling the ribosome (2005) (0)
- Crystal structure of ERa LBD in complex with RU100132 (2012) (0)
- A Structural View of the Retinoid Nuclear Receptors (1998) (0)
- 70S T.Th. ribosome functional complex with mRNA and E- and P-site tRNAs at 4.5A. This entry 2HGr contains 30S ribosomal subunit. The 50S ribosomal subunit can be found in PDB entry 2HGU. (2006) (0)
- STRUCTURE OF CYCLIN MCS2 (1997) (0)
- Crystallization and preliminary X-ray crystallographic study of the wild type and two mutants of the CP1 hydrolytic domain from Aquifex aeolicus leucyl-tRNA synthetase. (2005) (0)
- The walker-type atpase paby2304 of pyrococcus abyssi (2008) (0)
- CRYSTAL STRUCTURE OF THE LIGAND-BINDING DOMAIN OF THE ESTROGEN-RELATED RECEPTOR GAMMA IN COMPLEX WITH A STEROID RECEPTOR COACTIVATOR-1 PEPTIDE (2004) (0)
- Local Flexibility in Recognition Processes Between Macromolecules (1987) (0)
- Development of superagonist ligands for the vitamin D nuclear receptor, AMCR277A, -B and 2MeAMCR (2008) (0)
- Cell Metabolism Previews Structure of Full-Length PPAR g-RXR a : A Snapshot of a Functional Complex ? (0)
- Structural and Functional Role of INI1, a Cellular Cofactor of HIV-1 integrase in the Early Step of HIV Infection (2011) (0)
- Demonstration of method and / or assay of DNA damage in a DNA sample and its application to screening cytotoxic drugs acting on the DNA (1997) (0)
- Pig lens aldose reductase: purification and preliminary X-ray diffraction study. Oligomerization of the enzyme. (1987) (0)
- GLYCYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS COMPLEXED WITH GLYCYL-ADENYLATE (1999) (0)
- Dimerization of Escherichia coli DNA-gyrase B provides a structural mechanism for activating the ATPase catalytic center. (2000) (0)
- Crystal structure of the NF-YB/NF-YC histone pair (2003) (0)
- 5(th) EBSA & 15(th) IUPAB International Biophysics Congress Montpellier (France), August 27(th)-September 1(st), 2005 (2005) (0)
- tRNAArg recognition by yeast Arginyl-tRNA synthetase: crystal structure of the yeast arginyl-tRNA synthetase-yeast tRNAArg complex at 2.2 Å (2000) (0)
- Structural basis for cell-specific activity of NGFI-B/Nurr1 ligand-binding domains (2005) (0)
- Synchrotron data collection of 0.66 Å data for Aldose Reductase, an enzyme of MW = 36 Kdaltons (2000) (0)
- X-ray analyses of two evolutionarily different threonyl-tRNA synthetases which perform a function by supplementing their defects to each other in crenarchaea (2009) (0)
- STRUCTURE OF E. COLI THREONYL-TRNA SYNTHETASE COMPLEXED WITH ITS COGNATE TRNA (1999) (0)
- Communications orales - Fondamental (2008) (0)
- PIG ALDOSE REDUCTASE, HOLO FORM (1998) (0)
- Superagonistic action of 14-epi-vitamin D analogs correlates with enhanced vitamin D receptor - coactivator interactions (2005) (0)
- Local Flexibility in Recognition Processes Between (1987) (0)
- Crystal structure of ligand-binding domain of estrogen-related receptor alpha (ERRalpha) in complex with the peroxisome proliferators-activated receptor coactivator-1alpha box3 peptide (PGC-1alpha) (2008) (0)
- crystal structure of the ligand-binding domain of the estrogen-related receptor gamma in complex with 4-hydroxytamoxifen (2004) (0)
- Chapter 13 The Structure and Function of Ecdysone Receptors (0)
- tRNA recognition by procaryotic aspartyl tRNA-synthetases (1996) (0)
- FHUA FROM E. COLI, WITH ITS LIGAND FERRICHROME (1999) (0)
- 70S Thermus thermophilous ribosome functional complex with mRNA and E- and P-site tRNAs at 4.5A. (2014) (0)
- CRYSTAL STRUCTURE OF A TRUNCATED FORM OF THREONYL-TRNA SYNTHETASE COMPLEXED WITH A SERYL ADENYLATE ANALOG (2000) (0)
- Structures of the ribosome on different functional states (2008) (0)
- Allosteric Control of Cofactor Binding to Nuclear Hormone Receptors (2012) (0)
- The NF-Y transcription factor is structurally and functionally a sequence specific histone (2013) (0)
- Structure of Staphylococcus aureus threonyl-tRNA synthetase complexed with an analogue of threonyl adenylate (2003) (0)
- ISOTYPE SELECTIVITY OF THE HUMAN RETINOIC ACID NUCLEAR RECEPTOR HRAR: THE COMPLEX WITH THE PANAGONIST RETINOID BMS181156 (2000) (0)
- Crystal Structure of the human RXR alpha ligand binding domain bound to the eicosanoid DHA (Docosa Hexaenoic Acid) and a coactivator peptide (2002) (0)
- Aspartyl-tRNA synthetase complexed with aspartic acid (2010) (0)
- Crystal Structure of the Ligand-Binding Domains of the T.castaneum (Coleoptera) Heterodimer EcrUSP Bound to Ponasterone A (2007) (0)
- The aminoacylation of transfer RNAs : a structural point of view (1996) (0)
- Crystallization of E. coli aspartate beta-semialdehyde dehydrogenase. (1980) (0)
- CRYSTAL STRUCTURE at 1.9 ANGSTROEMS RESOLUTION OF THE HOMODIMER OF HUMAN RXR ALPHA LIGAND BINDING DOMAIN BOUND TO THE SYNTHETIC AGONIST COMPOUND BMS 649 AND A COACTIVATOR PEPTIDE (2002) (0)
- Inside Cover: Silicon Analogues of the RXR‐Selective Retinoid Agonist SR11237 (BMS649): Chemistry and Biology (ChemMedChem 7/2009) (2009) (0)
- Crystal structure of a snake venom cardiotoxin ( toxin / cytotoxin / membrane / x-rays ) (0)
- Aspartyl-tRNA synthetase complexed with aspartyl adenylate (2010) (0)
- Crystal structure of the 70S Thermus thermophilus ribosome showing how the 16S 3'-end mimicks mRNA E and P codons. This entry 2HGI contains 30S ribosomal subunit. The 50S ribosomal subunit can be found in PDB entry 2HGJ. (2006) (0)
- ENANTIOMER DISCRIMINATION ILLUSTRATED BY CRYSTAL STRUCTURES OF THE HUMAN RETINOIC ACID RECEPTOR HRARGAMMA LIGAND BINDING DOMAIN: THE COMPLEX WITH THE INACTIVE S-ENANTIOMER BMS270395. (2000) (0)
- Purification of the human RARgamma ligand-binding domain and crystallization of its complex with all-trans retinoic acid. (1997) (0)
- Crystal structure of the 43K ATPase domain of Thermus thermophilus gyrase B in complex with novobiocin (2002) (0)
- HTAFII18/HTAFII28 HETERODIMER CRYSTAL STRUCTURE (1999) (0)
- CRYSTAL STRUCTURE OF A WILD TYPE HER ALPHA LBD AT 2.9 ANGSTROM RESOLUTION (2002) (0)
- HTAFII18/HTAFII28 HETERODIMER CRYSTAL STRUCTURE WITH BOUND PCMBS (1999) (0)
- Crystal structure of zVDR L337H mutant-VD complex (2015) (0)
- CRYSTAL STRUCTURE OF YEAST ARGINYL-TRNA SYNTHETASE COMPLEXED WITH THE TRNAARG (2001) (0)
- Induction of colon cancer cell differentiation by non-steroidal analogs of 1,25-dihydroxyvitamin D-3 (2008) (0)
- CRYSTAL STRUCTURE OF FREE ASPARTYL-TRNA SYNTHETASE FROM ESCHERICHIA COLI (2000) (0)
- Superagonistic 14-epi-vitamin D analogs induce stronger vitamin D receptor – coactivator interactions (2004) (0)
- The 2.4 A crystal structure of the apo catalytic domain of coactivator-associated arginine methyl transferase I(CARM1,140-480). (2007) (0)
- METHIONYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS (1999) (0)
- Crystal structure of RARb LBD in complex with 9cis retinoic acid (2012) (0)
- Solution to the double discrimination problem by the class II threonyl-tRNA synthetase (2001) (0)
- Crystal structure of VDR LBD in complex with 2 alpha-(3-hydroxy-1-propoxy) calcitriol (2006) (0)
- Two structures of yeast tRNAAsp at 3 Ã resolution (1981) (0)
- FHUA FROM E. COLI (1999) (0)
- Polypeptides from the cell nucleus receptor of vitamins d, and their use in particular for the screening of vitamin D analogues (2000) (0)
- Crystal structure of the editing domain of threonyl-tRNA synthetase complexed with serine (2004) (0)
- X-Ray Crystallography of Membrane Proteins from Detergent Solution: The Structures of a Ligand-Gated Bacterial Membrane Receptor in Two Conformations; a Gallery at Atomic Resolution (2019) (0)
- Glycation restrains allosteric transition in hemoglobin: The molecular basis of oxidative stress under hyperglycemic conditions in diabetes (2017) (0)
- Structure-Function Analysis of the HIV-1 Integrase in Complex With Two Cellular Proteins: Ledgf and INI1 (2010) (0)
- Crystal structure of the editing domain of threonyl-tRNA synthetase complexed with seryl-3'-aminoadenosine (2004) (0)
- Crystal structure of the rNGFI-B ligand-binding domain (2005) (0)
- Automatic model correction by the wARP/ARP method (2000) (0)
- Crystal structure of Encephalitozoon cuniculi TAF5 N-terminal domain (2007) (0)
- Crystal structure of Vitamin D nuclear receptor ligand binding domain bound to a locked side-chain analog of calcitriol and SRC-1 peptide (2007) (0)
- Crystal structure of 20E bound EcR/USP (2007) (0)
- A molecular model for codon–anticodon recognition: the crystal structure of yeast tRNAAsp (1984) (0)
- Invertebrate Chordate Amphioxus Retinoid X Nuclear Receptor from the Nonduplicated Ligand-binding Domain of a Structural and Functional Insights into the Epigenetics: (2013) (0)
- Structural studies of pig lens aldose reductase: reversible dimerization of the enzyme. (1991) (0)
- Solution structure of the carboxy-terminal domain of human TFIIH P44 subunit (2005) (0)
- Crystal structure of putative threonyl-tRNA synthetase ThrRS-1 from Aeropyrum pernix (selenomethionine derivative) (2009) (0)
- Crystal structure of the vdr ligand binding domain complexed to TX522 (2005) (0)
- AEROMONAS PROTEOLYTICA AMINOPEPTIDASE COMPLEXED WITH THE INHIBITOR PARA-IODO-D-PHENYLALANINE HYDROXAMATE (1996) (0)
- Crystal structure of the LBD of VDR of Danio rerio in complex with calcitriol (2007) (0)
- Crystallography of the Complex tRNA Asp -Aspartyl-tRNA Synthetase from Yeast (1987) (0)
- 11 The RNP World (2006) (0)
- FREE ASPARTYL-TRNA SYNTHETASE (ASPRS) (E.C. 6.1.1.12) FROM YEAST (2000) (0)
- LIGAND-BINDING DOMAIN OF THE HUMAN RETINOIC ACID RECEPTOR GAMMA BOUND TO THE SYNTHETIC AGONIST BMS961 (1999) (0)
- Crystal structure of the human VDR ligand binding domain bound to the synthetic agonist compound 2alpha-methyl-AMCR277A(C23S) (2010) (0)
- Crystal Structure of the E. coli Aspartyl-tRNA Synthetase:Yeast tRNAasp:aspartyl-Adenylate Complex (1999) (0)
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