Dirk Trauner

Dirk Trauner's AcademicInfluence.com Rankings

Dirk Trauner

Chemistry

#2449

World Rank

#3359

Historical Rank

Organic Chemistry

#358

World Rank

#425

Historical Rank

chemistry Degrees

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Chemistry

Dirk Trauner's Degrees

PhD Chemistry University of California, Berkeley
Bachelors Chemistry University of California, Berkeley

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Dirk Trauner's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Light-activated ion channels for remote control of neuronal firing (2004) (647)
The B-Alkyl Suzuki-Miyaura Cross-Coupling Reaction: Development, Mechanistic Study, and Applications in Natural Product Synthesis A list of abbreviations can be found at the end of the article. (2001) (584)
Allosteric control of an ionotropic glutamate receptor with an optical switch (2006) (525)
A roadmap to success in photopharmacology. (2015) (421)
In Vivo Photopharmacology. (2018) (387)
Optogenetic dissection of a behavioral module in the vertebrate spinal cord (2009) (381)
Beta Cell Hubs Dictate Pancreatic Islet Responses to Glucose (2016) (332)
Remote Control of Neuronal Activity with a Light-Gated Glutamate Receptor (2007) (330)
Reversible photomechanical switching of individual engineered molecules at a metallic surface. (2006) (312)
Extraction of Photogenerated Electrons and Holes from a Covalent Organic Framework Integrated Heterojunction (2014) (299)
Photoswitchable Inhibitors of Microtubule Dynamics Optically Control Mitosis and Cell Death (2015) (251)
Biosynthetic and biomimetic electrocyclizations. (2005) (224)
Photochemical control of endogenous ion channels and cellular excitability (2008) (208)
Photochemical Restoration of Visual Responses in Blind Mice (2012) (207)
Photochromic blockers of voltage-gated potassium channels. (2009) (188)
Optical Control of Metabotropic Glutamate Receptors (2013) (175)
A red-shifted, fast-relaxing azobenzene photoswitch for visible light control of an ionotropic glutamate receptor. (2013) (167)
Mechanisms of photoswitch conjugation and light activation of an ionotropic glutamate receptor (2007) (166)
LiGluR restores visual responses in rodent models of inherited blindness. (2011) (161)
New photochemical tools for controlling neuronal activity (2009) (159)
Label-Free Microscale Thermophoresis Discriminates Sites and Affinity of Protein–Ligand Binding** (2012) (156)
Restoring Visual Function to Blind Mice with a Photoswitch that Exploits Electrophysiological Remodeling of Retinal Ganglion Cells (2014) (154)
The chemistry of marine furanocembranoids, pseudopteranes, gersolanes, and related natural products. (2008) (152)
DieB-Alkyl-Suzuki-Miyaura-Kreuzkupplung: Entwicklung, Untersuchungen zum Mechanismus und Anwendungen in der Naturstoffsynthese (2001) (149)
Optochemical control of genetically engineered neuronal nicotinic acetylcholine receptors. (2012) (146)
Optochemical genetics. (2011) (145)
Tuning photochromic ion channel blockers. (2011) (141)
Rapid optical control of nociception with an ion channel photoswitch (2012) (138)
Enantioselective Nazarov reactions through catalytic asymmetric proton transfer. (2004) (137)
Reversibly caged glutamate: a photochromic agonist of ionotropic glutamate receptors. (2007) (135)
PHOTACs enable optical control of protein degradation (2020) (134)
A light-gated, potassium-selective glutamate receptor for the optical inhibition of neuronal firing (2010) (126)
A structural link between inactivation and block of a K+ channel (2008) (122)
Engineering light-gated ion channels. (2006) (120)
Azo-propofols: photochromic potentiators of GABA(A) receptors. (2012) (120)
Efficient Nazarov cyclizations of 2-alkoxy-1,4-pentadien-3-ones. (2003) (119)
Science of Synthesis: Houben-Weyl Methods of Molecular Transformations (2008) (118)
Concise total synthesis of (-)-frondosin B using a novel palladium-catalyzed cyclization. (2002) (113)
Photoswitchable fatty acids enable optical control of TRPV1 (2015) (104)
Photoswitchable diacylglycerols enable optical control of protein kinase C. (2016) (101)
Concise synthesis of (+/-)-rhazinilam through direct coupling. (2005) (98)
A photochromic agonist for μ-opioid receptors. (2014) (98)
ortho-Quinone methides from para-quinones: total synthesis of rubioncolin B. (2008) (98)
Photochemical tools for remote control of ion channels in excitable cells (2005) (97)
The V-ATPase-inhibitor archazolid abrogates tumor metastasis via inhibition of endocytic activation of the Rho-GTPase Rac1. (2012) (97)
Optical control of insulin release using a photoswitchable sulfonylurea (2014) (97)
Total synthesis of (-)-heptemerone B and (-)-guanacastepene E. (2006) (96)
Synthesis of taiwaniaquinoids via Nazarov triflation. (2006) (92)
Structural basis of open channel block in a prokaryotic pentameric ligand-gated ion channel (2010) (92)
Light-induced depolarization of neurons using a modified Shaker K(+) channel and a molecular photoswitch. (2006) (90)
Exploring biosynthetic relationships among furanocembranoids: synthesis of (-)-bipinnatin J, (+)-intricarene, (+)-rubifolide, and (+)-isoepilophodione B. (2006) (90)
Total synthesis of (-)-archazolid B. (2007) (89)
Mode of Cell Death Induction by Pharmacological Vacuolar H+-ATPase (V-ATPase) Inhibition* (2012) (87)
Total synthesis of (+/-)-rhazinal using novel palladium-catalyzed cyclizations. (2009) (85)
Orthogonal Optical Control of a G Protein-Coupled Receptor with a SNAP-Tethered Photochromic Ligand (2015) (82)
Synthesis of Redshifted Azobenzene Photoswitches by Late-Stage Functionalization. (2016) (82)
Morphine Synthesis and Biosynthesis-An Update (2000) (80)
Synthetic approaches towards alkaloids bearing α-tertiary amines. (2016) (76)
Nanosculpting reversed wavelength sensitivity into a photoswitchable iGluR (2009) (76)
Expedient synthesis of (+/-)-bipinnatin J. (2006) (76)
Pharmacology of ionotropic glutamate receptors: A structural perspective. (2010) (73)
Optical control of acetylcholinesterase with a tacrine switch. (2014) (70)
Optical Control of Insulin Secretion Using an Incretin Switch (2015) (67)
Optogenetic photochemical control of designer K+ channels in mammalian neurons. (2011) (66)
Biomimetic synthesis and structure elucidation of rubicordifolin, a cytotoxic natural product from Rubia cordifolia. (2005) (66)
An eight-step synthesis of epicolactone reveals its biosynthetic origin. (2015) (65)
A photochromic agonist of AMPA receptors. (2012) (64)
All optical interface for parallel, remote, and spatiotemporal control of neuronal activity. (2007) (63)
Regulating Enzymatic Activity with a Photoswitchable Affinity Label (2008) (62)
Mining the tetraene manifold: total synthesis of complex pyrones from Placobranchus ocellatus. (2005) (62)
Pericyclic reactions of prenylated naphthoquinones: biomimetic syntheses of mollugin and microphyllaquinone. (2005) (62)
Restoration of patterned vision with an engineered photoactivatable G protein-coupled receptor (2017) (61)
Computational Design and Synthesis of a Deeply Red-Shifted and Bistable Azobenzene (2020) (61)
Long wavelength optical control of glutamate receptor ion channels using a tetra-ortho-substituted azobenzene derivative. (2014) (60)
Synthetic studies toward SNF4435 C and SNF4435 D. (2002) (59)
Development of a new photochromic ion channel blocker via azologization of fomocaine. (2014) (59)
Pre-Exposure Prophylaxis (PrEP) (2019) (58)
Synthesis of Photoswitchable Δ9-Tetrahydrocannabinol Derivatives Enables Optical Control of Cannabinoid Receptor 1 Signaling. (2017) (58)
Optical control of NMDA receptors with a diffusible photoswitch (2015) (58)
An electrochemical approach to the guanacastepenes. (2005) (57)
Vacuolar-ATPase Inhibition Blocks Iron Metabolism to Mediate Therapeutic Effects in Breast Cancer. (2015) (57)
Dual optical control and mechanistic insights into photoswitchable group II and III metabotropic glutamate receptors (2017) (56)
Characterization of a Diffusible Signaling Factor from Xylella fastidiosa (2013) (56)
A family of photoswitchable NMDA receptors (2016) (56)
Protein surface recognition by rational design: nanomolar ligands for potassium channels. (2003) (56)
Microtubules control cellular shape and coherence in amoeboid migrating cells (2019) (54)
Catalysis of 6pi electrocyclizations. (2008) (54)
Optical Control of Lipid Rafts with Photoswitchable Ceramides. (2016) (53)
Light-Controlled Membrane Mechanics and Shape Transitions of Photoswitchable Lipid Vesicles. (2017) (52)
Palladium-catalyzed couplings to nucleophilic heteroarenes: the total synthesis of (−)-frondosin B (2004) (51)
Biomimetic synthesis of the IDO inhibitors exiguamine A and B. (2008) (50)
Effect of humidity on stiction and friction of the head/disk interface (1990) (49)
Calix[4]arene-based conical-shaped ligands for voltage-dependent potassium channels (2009) (49)
Optical Control of Dopamine Receptors Using a Photoswitchable Tethered Inverse Agonist. (2017) (49)
An efficient synthesis of loline alkaloids. (2011) (48)
Mapping the Azolog Space Enables the Optical Control of New Biological Targets (2019) (48)
Controlling epithelial sodium channels with light using photoswitchable amilorides. (2014) (47)
Biomimetic synthesis of antimalarial naphthoquinones. (2005) (47)
The in vivo chemistry of photoswitched tethered ligands. (2014) (47)
Synthetic approaches toward sesterterpenoids. (2012) (46)
Optical control of TRPV1 channels. (2013) (46)
Light-Dark Adaptation of Channelrhodopsin Involves Photoconversion between the all-trans and 13-cis Retinal Isomers. (2015) (46)
Synthetic studies toward the guanacastepenes. (2003) (45)
Biomimetic total synthesis of santalin Y. (2015) (45)
Sign Inversion in Photopharmacology: Incorporation of Cyclic Azobenzenes in Photoswitchable Potassium Channel Blockers and Openers. (2019) (45)
Photochemical origin of the immunosuppressive SNF4435C/D and formation of orinocin through "polyene splicing". (2006) (44)
Total synthesis of (-)-SNF4435 C and (+)-SNF4435 D. (2005) (44)
Biomimetic synthesis of the shimalactones. (2008) (44)
Concise total syntheses of variecolortides A and B through an unusual hetero-Diels-Alder reaction. (2011) (43)
Optical Control of Sphingosine-1-Phosphate Formation and Function (2019) (43)
Wild-Type Monomeric α-Synuclein Can Impair Vesicle Endocytosis and Synaptic Fidelity via Tubulin Polymerization at the Calyx of Held (2017) (42)
A photoactive porphyrin-based periodic mesoporous organosilica thin film. (2013) (42)
The total synthesis of (-)-amathaspiramide F. (2002) (42)
Vinyl quinones as Diels-Alder dienes: concise synthesis of (-)-halenaquinone. (2008) (41)
Synthesis of Enantiomerically Pure Morphine Alkaloids: The Hydrophenanthrene Route. (1998) (41)
PhoDAGs Enable Optical Control of Diacylglycerol-Sensitive Transient Receptor Potential Channels. (2017) (40)
Biomimetic synthesis of (-)-pycnanthuquinone C through the Diels-Alder reaction of a vinyl quinone. (2010) (40)
AzoCholine Enables Optical Control of Alpha 7 Nicotinic Acetylcholine Receptors in Neural Networks. (2015) (40)
Furans as Versatile Synthons: Total Syntheses of Caribenol A and Caribenol B. (2017) (40)
Biomimetic synthesis of the calcineurin phosphatase inhibitor dibefurin. (2014) (40)
Toward the total synthesis of maoecrystal V: establishment of contiguous quaternary stereocenters. (2010) (39)
Photopharmacological control of bipolar cells restores visual function in blind mice (2017) (39)
Optical control of neuronal activity using a light-operated GIRK channel opener (LOGO) (2015) (38)
Restoring Light Sensitivity in Blind Retinae Using a Photochromic AMPA Receptor Agonist (2015) (38)
Rational Design of a Chiral Palladium(0) Olefin Complex of Unprecedented Stability (2005) (38)
Biomimetic Synthesis of Antimalarial Naphthoquinones. (2007) (38)
A total synthesis prompts the structure revision of haouamine B. (2012) (38)
Studies towards the total synthesis of halichlorine: asymmetric synthesis of the spiroquinolizidine subunit (1999) (38)
Manipulating midbrain dopamine neurons and reward-related behaviors with light-controllable nicotinic acetylcholine receptors (2018) (36)
The B‐Alkyl Suzuki—Miyaura Cross‐Coupling Reaction: Development, Mechanistic Study, and Applications in Natural Product Synthesis (2010) (36)
Biomimetic synthesis of (+/-)-pinnatal and (+/-)-sterekunthal A. (2003) (35)
Biomimetic synthesis of elysiapyrones A and B. (2005) (35)
Light-Controlled Lipid Interaction and Membrane Organization in Photolipid Bilayer Vesicles. (2018) (35)
A Biomimetic Synthesis Elucidates the Origin of Preuisolactone A. (2019) (35)
Photochrome Liganden für spannungsgesteuerte Kaliumkanäle (2009) (35)
A red-shifted photochromic sulfonylurea for the remote control of pancreatic beta cell function. (2015) (35)
Genetically Targeted Optical Control of an Endogenous G Protein-Coupled Receptor. (2019) (35)
Synthetic retinal analogues modify the spectral and kinetic characteristics of microbial rhodopsin optogenetic tools (2014) (35)
Allosteric Optical Control of a Class B G‐Protein‐Coupled Receptor (2016) (34)
The phenanthrenone approach to opium alkaloids: Formal total synthesis of morphine by sigmatropic rearrangement (1997) (34)
Photochemical formation of intricarene (2014) (34)
Total synthesis of (+/-)-photodeoxytridachione through a Lewis acid catalyzed cyclization. (2003) (33)
Photoswitchable Lipids (2020) (33)
Optical control of L-type Ca2+ channels using a diltiazem photoswitch (2018) (32)
Development of novel lewis acid catalyzed cycloisomerizations: synthesis of bicyclo[3.1.0]hexenes and cyclopentenones (2003) (32)
Inter-kingdom Signaling by the Legionella Quorum Sensing Molecule LAI-1 Modulates Cell Migration through an IQGAP1-Cdc42-ARHGEF9-Dependent Pathway (2015) (31)
The α‐hydroxyketone LAI‐1 regulates motility, Lqs‐dependent phosphorylation signalling and gene expression of Legionella pneumophila (2016) (31)
Synthetic studies toward the haouamines. (2006) (30)
The total synthesis of (-)-nitidasin. (2014) (30)
Expedient Synthesis of (+)-Lycopalhine A. (2016) (30)
Photoswitchable paclitaxel-based microtubule stabilisers allow optical control over the microtubule cytoskeleton (2020) (29)
Total synthesis of coralloidolides A, B, C, and E. (2010) (29)
Specificity and Speed: Tethered Photopharmacology. (2017) (29)
A Conia-Ene-Type Cyclization under Basic Conditions Enables an Efficient Synthesis of (-)-Lycoposerramine R. (2017) (29)
An Oxidative Approach Enables Efficient Access to Cyclic Azobenzenes. (2019) (28)
Biomimetic synthesis of (±)-merochlorin B. (2014) (28)
Insight into the Mechanism of the Saegusa Oxidation: Isolation of a Novel Palladium(0)-Tetraolefin Complex. (1999) (28)
A practical variant of the Claisen-Eschenmoser rearrangement: Synthesis of unsaturated morpholine amides (2002) (28)
SNAP-tagged nanobodies enable reversible optical control of a G protein-coupled receptor via a remotely tethered photoswitchable ligand (2018) (27)
Body Mass Index in Multiple Sclerosis modulates ceramide-induced DNA methylation and disease course (2019) (27)
Optical tools for understanding the complexity of β-cell signalling and insulin release (2018) (27)
A Synthesis of (±)-Aplydactone. (2016) (27)
Conditional and Reversible Activation of Class A and B G Protein-Coupled Receptors Using Tethered Pharmacology (2018) (27)
New players in phototherapy: photopharmacology and bio-integrated optoelectronics. (2019) (26)
Structure and Biosynthesis of Crocagins: Polycyclic Posttranslationally Modified Ribosomal Peptides from Chondromyces crocatus. (2017) (26)
Remote control of glucose homeostasis in vivo using photopharmacology (2017) (26)
Total synthesis of exiguamines A and B inspired by catecholamine chemistry. (2012) (26)
A photoswitchable neurotransmitter analogue bound to its receptor. (2013) (25)
Biomimetic synthesis of santalin A,B and santarubin A,B, the major colorants of red sandalwood. (2013) (25)
The total synthesis of (-)-crispatene. (2004) (25)
A unified approach to trans-hydrindane sesterterpenoids. (2012) (25)
Total Synthesis of the Norhasubanan Alkaloid Stephadiamine. (2018) (25)
Biomimetic Synthesis of Complex Flavonoids Isolated from Daemonorops "Dragon's Blood". (2017) (24)
Chapter 1 - Restoring Vision to the Blind: The New Age of Implanted Visual Prostheses. (2014) (24)
Exploring the Pharmacology and Action Spectra of Photochromic Open‐Channel Blockers (2012) (24)
Development of a Friedel-Crafts triflation. (2006) (24)
New Ventures in the Construction of Complex Heterocycles: Synthesis of Morphine and Hasubanan Alkaloids (1998) (24)
Intramolecular Diels-Alder reactions of 5-vinyl-1,3-cyclohexadienes. (2003) (23)
Reductive Cyclization of δ-Hydroxy Nitriles: A New Synthesis of Glycosylamines† (2003) (23)
Stereoselective synthesis of cyercene A and the placidenes. (2005) (22)
An approach to aminonaphthoquinone ansamycins using a modified Danishefsky diene. (2012) (22)
Optical Manipulation of F-Actin with Photoswitchable Small Molecules. (2020) (22)
Mechanistic investigations of the acid-catalyzed cyclization of a vinyl ortho-quinone methide. (2008) (22)
A (+)‐Larixol Congener with High Affinity and Subtype Selectivity toward TRPC6 (2018) (22)
Evolution of a Unified Strategy for Complex Sesterterpenoids: Progress toward Astellatol and the Total Synthesis of (-)-Nitidasin. (2015) (21)
The Chemist and the Architect. (2018) (21)
PRACTICAL SYNTHESIS OF (-)-MORPHINE (1999) (21)
Total synthesis of sandresolide B and amphilectolide. (2014) (21)
A zinc phthalocyanine based periodic mesoporous organosilica exhibiting charge transfer to fullerenes. (2014) (20)
Photoswitchable Inhibitor of a Glutamate Transporter. (2017) (20)
A Lipid Photoswitch Controls Fluidity in Supported Bilayer Membranes. (2020) (20)
Optimized Photoactivatable Lipid Nanoparticles Enable Red Light Triggered Drug Release. (2021) (20)
Biomimetic Synthesis of (+)-Aspergillin PZ. (2018) (20)
Concise synthesis of the bacterial DNA primase inhibitor (+) -Sch 642305. (2007) (19)
Functionalized azobenzenes through cross-coupling with organotrifluoroborates (2007) (19)
Optical Control of a Biological Reaction-Diffusion System. (2018) (19)
Relative positioning of classical benzodiazepines to the γ2-subunit of GABAA receptors. (2014) (19)
Photochemische Herkunft der Immunsuppressiva SNF4435C/D und Bildung von Orinocin durch “Polyen‐Splicing” (2006) (19)
A step toward polytwistane: synthesis and characterization of C2-symmetric tritwistane. (2014) (19)
Stereoselective total syntheses of herbicidin C and aureonuclemycin through late-stage glycosylation. (2012) (18)
Optical modulation of neurotransmission using calcium photocurrents through the ion channel LiGluR (2013) (18)
Crocipodin, a benzotropolone pigment from the mushroom Leccinum crocipodium (Boletales) (2011) (18)
Optical control of AMPA receptors using a photoswitchable quinoxaline-2,3-dione antagonist† †Electronic supplementary information (ESI) available: Experimental procedures and characterisation data. See DOI: 10.1039/c6sc01621a Click here for additional data file. (2016) (18)
Thiocarbonyl Ylide Chemistry Enables a Concise Synthesis of (±)-Hippolachnin A. (2017) (18)
A Predictive Approach for the Optical Control of Carbonic Anhydrase II Activity. (2018) (17)
Optical control of GIRK channels using visible light. (2017) (17)
Optical Control of Lysophosphatidic Acid Signaling. (2020) (17)
Stereoselective syntheses of the bioactive polypropionates aureothin, N-acetylaureothamine, and aureonitrile. (2005) (17)
Theoretical investigation of the rubicordifolin cascade. (2010) (17)
Total Syntheses of Cystobactamids and Structural Confirmation of Cystobactamid 919-2. (2017) (17)
Optical control of targeted protein degradation. (2021) (16)
Unravelling Photochemical Relationships Among Natural Products from Aplysia dactylomela (2016) (16)
Azobenzene-based inhibitors of human carbonic anhydrase II (2015) (16)
Ein photochromer Agonist für μ‐Opioidrezeptoren (2014) (16)
Optical control of GPR 40 signalling in pancreatic β-cells (2017) (16)
A Signal Processing Analysis of Purkinje Cells in vitro (2010) (16)
Enantioselective Synthesis and Racemization of (-)-Sinoracutine. (2017) (15)
Studies toward the biomimetic total synthesis of (-)-PF-1018. (2013) (15)
Development of a photoswitchable antagonist of NMDA receptors (2017) (15)
Intramolecular vinyl quinone Diels-Alder reactions: asymmetric entry to the cordiachrome core and synthesis of (-)-isoglaziovianol. (2013) (15)
Photohormones Enable Optical Control of the Peroxisome Proliferator-Activated Receptor Gamma (PPAR). (2020) (15)
Selective Lithiation, Magnesiation, and Zincation of Unsymmetrical Azobenzenes Using Continuous Flow. (2017) (15)
Photosensitized conversion of 9,10-deoxytridachione to photodeoxytridachione. (2005) (15)
Asymmetric Synthesis of the Antiviral Diterpene Wickerol A. (2017) (15)
Dienophile twisting and substituent effects influence reaction rates of intramolecular Diels-Alder cycloadditions: a DFT study. (2005) (14)
Optische Kontrolle der Acetylcholinesterase mit einem schaltbaren Tacrin (2014) (14)
Synthetic studies toward A-74528. (2011) (14)
How Photoswitchable Lipids Affect the Order and Dynamics of Lipid Bilayers and Embedded Proteins. (2021) (14)
Total Synthesis of (±)–Exotine B (2018) (13)
On the Conformations of Halichlorine and the Pinnaic Acids: Nitrogen Inversion as a Possible Determinant of Biological Profile (2000) (13)
Optical Control of Phosphatidic Acid Signaling (2021) (13)
The Phenanthrenone Approach to Opium Alkaloids: Formal Total Synthesis of Morphine by Sigmatropic Rearrangement. (1997) (13)
Frictional behavior of magnetic recording disks (1990) (13)
Optical control of calcium-regulated exocytosis. (2013) (13)
Concise Total Synthesis of (−)-Frondosin B Using a Novel Palladium-Catalyzed Cyclization This work was supported by a generous gift from Merck & Co. (2002) (13)
Biomimetische Totalsynthese von Santalin Y (2015) (13)
Totalsynthese von (+)‐Halichlorin, einem Inhibitor der Expression von VCAM‐1 (1999) (12)
Biomimetische Synthese von (−)‐Pycnanthuchinon C über eine Vinylchinon‐Diels‐Alder‐Reaktion (2010) (12)
A Versatile Bis-Allylboron Reagent for the Stereoselective Synthesis of Chiral Diols. (2018) (12)
Synthetic studies toward polytwistane hydrocarbon nanorods. (2015) (12)
Optical Control of Cytokine Production Using Photoswitchable Galactosylceramides. (2019) (12)
Chapter 7- Restoring Vision to the Blind: Advancements in Vision Aids for the Visually Impaired. (2014) (12)
Enzymatic desymmetrization of a centrosymmetric diacetate (2003) (12)
Formale Totalsynthese von (−)‐Morphin über konjugierte Cuprataddition (1996) (12)
Selective Synthesis of Divergolide I. (2018) (12)
Total Synthesis of Lycopladine A and Carinatine A via a Base-Mediated Carbocyclization. (2017) (12)
Optical manipulation of sphingolipid biosynthesis using photoswitchable ceramides (2019) (12)
Computational Exploration of the Mechanism of Critical Steps in the Biomimetic Synthesis of Preuisolactone A, and Discovery of New Ambimodal (5 + 2)/(4 + 2) Cycloadditions. (2021) (12)
Controlling the Covalent Reactivity of a Kinase Inhibitor with Light. (2021) (12)
Total synthesis of newbouldine via reductive N-N bond formation (2010) (12)
Selective Photoswitchable Allosteric Agonist of a G Protein-Coupled Receptor (2021) (11)
Potassium channels: symmetric, selective, and sensitive. (2003) (11)
Biomimetische Synthese komplexer Flavonoide isoliert aus Daemonorops-“Drachenblut” (2017) (11)
Photolipid Bilayer Permeability is Controlled by Transient Pore Formation. (2020) (11)
Total synthesis of smenochromene B through ring contraction (2007) (11)
Natural product anticipation through synthesis (2022) (11)
Reflections on Racemic Natural Products (2020) (10)
Toward the Total Synthesis of Divergolides C and D (2013) (10)
The crystal structure of the Dess–Martin periodinane (2012) (10)
Transformation of Receptor Tyrosine Kinases into Glutamate Receptors and Photoreceptors. (2019) (10)
Metabolic Modulation of Potassium Channels (2004) (10)
Borane-ammonia complexes stabilized by hydrogen bonding. (2002) (10)
Reversible optical control of F1Fo‐ATP synthase using photoswitchable inhibitors (2018) (10)
Total synthesis of the proposed structure of trichodermatide A. (2014) (10)
A Photoswitchable Inhibitor of the Human Serotonin Transporter. (2020) (9)
Toward (-)-Enterocin: An Improved Cuprate Barbier Protocol To Overcome Strain and Sterical Hindrance. (2018) (9)
Richard Willstätter and the 1915 Nobel Prize in chemistry. (2015) (9)
Total synthesis of herbicidin C and aureonuclemycin: impasses and new avenues. (2013) (9)
Development of an iron(II)-catalyzed aerobic catechol cleavage and biomimetic synthesis of betanidin. (2014) (9)
Photoswitchable Serotonins for Optical Control of the 5-HT2A Receptor. (2021) (9)
Two-Dimensional Electronic Spectroscopy Reveals the Spectral Dynamics of Förster Resonance Energy Transfer (2019) (9)
Short Photoswitchable Ceramides Enable Optical Control of Apoptosis. (2021) (9)
Optical Membrane Control with Red Light Enabled by Red-Shifted Photolipids. (2021) (9)
Optical Control of a Delayed Rectifier and a Two-Pore Potassium Channel with a Photoswitchable Bupivacaine. (2018) (9)
Photopharmacologic Vision Restoration Reduces Pathological Rhythmic Field Potentials in Blind Mouse Retina (2019) (9)
Perfect and Defective 13C-Furan-Derived Nanothreads from Modest-Pressure Synthesis Analyzed by 13C NMR. (2021) (8)
Bilirubin in a new light. (2013) (8)
Conjugate addition of allyl stannanes with concomitant triflation. (2008) (8)
Bioinspired Synthesis of (-)-PF-1018. (2019) (8)
A Highly Convergent and Biomimetic Total Synthesis of Portentol. (2015) (8)
Concise Stereoselective Routes to Advanced Intermediates Related to Natural and Unnatural Pinnaic Acid (2001) (8)
Photopharmacological control of cell signaling with photoswitchable lipids. (2022) (8)
Metabolic tuning of inhibition regulates hippocampal neurogenesis in the adult brain (2020) (8)
Markierungsfreie “Microscale Thermophoresis” zur Bestimmung von Bindestellen und Affinitäten bei Protein-Liganden-Wechselwirkungen† (2012) (8)
Cell specific photoswitchable agonist for reversible control of endogenous dopamine receptors (2021) (8)
Totalsynthese von Coralloidolid A, B, C und E† (2010) (8)
Kompakte Totalsynthese von Variecolortid A und B durch eine ungewöhnliche Hetero‐Diels‐Alder‐Reaktion (2011) (8)
Azomethine Ylide Cycloaddition Approach toward Dendrobine: Synthesis of 5-Deoxymubironine C. (2018) (8)
A Pentasymmetric Open Channel Blocker for Cys-Loop Receptor Channels (2014) (7)
Biomimetic Approach Toward Enterocin and Deoxyenterocin. (2018) (7)
Finding function and form. (2014) (7)
Medium-Chain Lipid Conjugation Facilitates Cell-Permeability and Bioactivity. (2022) (7)
Total Synthesis of Crocagin A. (2017) (7)
Synthesis and biological evaluation of (±)-hippolachnin and analogs (2019) (7)
Calculated Nuclear Magnetic Resonance Spectra of Polytwistane and Related Hydrocarbon Nanorods. (2015) (7)
Optische Kontrolle der Insulinsekretion mit einem Inkretinschalter (2015) (7)
Ein photochromer Agonist für AMPA‐Rezeptoren (2012) (7)
Die Totalsynthese von (−)‐Nitidasin (2014) (7)
Optische Kontrolle von TRPV1‐Kanälen (2013) (6)
Functionalized Azobenzenes Through Cross‐Coupling with Organotrifluoroborates. (2007) (6)
The Meerwein–Eschenmoser–Claisen Rearrangement (2007) (6)
Light-induced lipid mixing implies a causal role of lipid splay in membrane fusion. (2020) (6)
Restoring visual function to blind mice with photoswitches that selectively target the degenerated retina. (2014) (6)
Optical control of GPR40 signalling in pancreatic β-cells† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c7sc01475a (2017) (6)
Molecular switches and cages (2012) (6)
Mapping the Chemistry of Highly Unsaturated Pyrone Polyketides (2006) (6)
Allosterische optische Steuerung eines Klasse-B-G-Protein-gekoppelten Rezeptors (2016) (6)
Eine Conia‐En‐artige Cyclisierung unter basischen Bedingungen ermöglicht die effiziente Synthese von (−)‐Lycoposerramin R (2017) (6)
Optical Control of Metabotropic Glutamate Receptors for Probing of G Protein Signaling and Receptor Activation Mechanism (2012) (5)
Toward the total synthesis of ansalactam A (2014) (5)
Switchable Proteins and Channels (2011) (5)
Molecular Dynamics Investigation of gluazo, a Photo-Switchable Ligand for the Glutamate Receptor GluK2 (2015) (5)
Introduction: Optogenetics and Photopharmacology. (2018) (5)
Einblick in den Mechanismus der Saegusa‐Oxidation: Isolierung eines neuartigen Palladium(0)‐Tetraolefin‐Komplexes (1999) (5)
Der Chemiker und der Architekt (2018) (5)
Evolution of a Synthetic Strategy for the Variecolortides (2012) (5)
Morphine Synthesis and Biosynthesis — An Update (2000) (5)
Ligand Photo-Isomerization Triggers Conformational Changes in iGluR2 Ligand Binding Domain (2014) (5)
Tunable oscillations in the Purkinje neuron. (2011) (4)
Intramolecular Vinyl Quinone Diels—Alder Reactions: Asymmetric Entry to the Cordiachrome Core and Synthesis of (—)‐Isoglaziovianol. (2014) (4)
A 1H NMR assay for measuring the photostationary States of photoswitchable ligands. (2013) (4)
The photopharmacology of nicotinic acetylcholine receptors (2016) (4)
Photoswitchable microtubule stabilisers optically control tubulin cytoskeleton structure and function (2019) (4)
A concise synthesis of tetrodotoxin (2022) (4)
Photopharmacological control of lipid function. (2020) (4)
Optical Control of Mitosis with a Photoswitchable Eg5 Inhibitor. (2021) (4)
Reversible Photomechanical Switching of Individual Engineered Molecules at a Surface (2007) (4)
Potential energy function for a photo‐switchable lipid molecule (2020) (4)
Chemische Struktur und Biosynthese der Crocagine, polycyclischer Peptide ribosomalen Ursprungs aus Chondromyces crocatus (2017) (4)
ortho‐Quinone Methides from para‐Quinones: Total Synthesis of Rubioncolin B. (2008) (4)
Concise Synthesis of (±)-Smenochromene D (= Likonide B) (2005) (4)
Optical Control of Adenosine-Mediated Pain Modulation (2021) (3)
Molecular Aesthetics. Edited by Peter Weibel and Ljiljana Fruk. (2015) (3)
Biomimetische Synthese von Santalin A,B und Santarubin A,B, den Hautpigmenten des Roten Sandelholzes† (2013) (3)
Concise Asymmetric Synthesis of Kweichowenol A (2018) (3)
Tetraphenylporphyrin derivative specifically blocks members of the voltage-gated potassium channel subfamily Kv1 (2013) (3)
Stereoselektive Totalsynthese von Herbicidin C und Aureonuclemycin durch späte N-Glykosylierung (2012) (3)
Erratum: Synthetic retinal analogs modify the spectral and kinetic characteristics of microbial rhodopsin optogenetic tools (2015) (3)
Cholesterol and sphingomyelin are critical for Fcγ receptor-mediated phagocytosis of Cryptococcus neoformans by macrophages (2021) (3)
De novo Design of SARS-CoV-2 Main Protease Inhibitors (2021) (3)
On the development of catalytic carba-6π electrocyclizations (2010) (3)
A Synthesis of Crocagin A (2017) (3)
Leiomyoma of the rectum with unusual clinical features. (1960) (3)
Photopharmacology: Controlling Native Voltage-Gated Ion Channels with Light (2010) (2)
Synthesis of (-)-Halenaquinone (2009) (2)
A Chemoselective Conjugation of Peptides with Electron-Rich (Hetero)Arenes (2019) (2)
Pericyclic Reactions of Prenylated Naphthoquinones: Biomimetic Syntheses of Mollugin (I) and Microphyllaquinone (II). (2006) (2)
Synthesis of the Loline Alkaloids (2011) (2)
Dexamethasone – A Corticosteroid Reduces Death in Severe COVID-19 (2020) (2)
Synthesis of immunomodulatory marine natural products. (2000) (2)
2.19 Selected Diastereoselective Reactions: Electrocyclizations (2012) (2)
Chemical neurobiology--introduction. (2010) (2)
Classics in Stereoselective Synthesis. By Erick M. Carreira and Lisbet Kvaerno. (2009) (2)
Concise Stereoselective Routes to Advanced Intermediates Related to Natural and Unnatural Pinnaic Acid. (2002) (2)
Cholinergic Photopharmacology – Controlling nicotinic and muscarinic Acetylcholine Receptors with Photoswitchable Molecules (2015) (2)
Introduction: Chemical approaches to neurobiology. (2008) (2)
Optical control of neuronal activities with photoswitchable nanovesicles (2022) (2)
Eine Synthese von (±)‐Aplydacton (2016) (2)
Optical control of the nuclear bile acid receptor FXR with a photohormone† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c9sc02911g (2019) (2)
A Photohormone for Light-Dependent Control of PPARα in Live Cells. (2021) (2)
Richard Willstätter und der Chemienobelpreis des Jahres 1915 (2015) (2)
Enantioselektive Synthese und Racemisierung von (−)‐Sinoracutin (2017) (2)
Ein vielseitiges Bisallylbor‐Reagenz für die stereoselektive Synthese von chiralen Diolen (2018) (2)
Molecular Aesthetics. Herausgegeben von Peter Weibel und Ljiljana Fruk. (2015) (2)
Stereoselektive Insertion von Ketenen in O, O‐Acetale: Synthese von β‐Alkoxyestern und 1,4‐Dioxepan‐5‐onen (1996) (1)
Direct Catalytic Asymmetric Amination of Aldehydes: Synthesis of Evans Oxazolidinones and α-Amino Acids (2003) (1)
Structural Diversity of Photoswitchable Sphingolipids for Optodynamic Control of Lipid Raft Microdomains (2021) (1)
Corrigendum: Total Synthesis of Coralloidolides A, B, C, and E. (2015) (1)
Lysine-Selective Oxidative Addition Complexes for the Conjugation of Proteins, Antibodies, and Peptides (2021) (1)
Optical Control of Translation with a Puromycin-Photoswitch (2022) (1)
Photoactivation of a Mechanosensitive Channel (2022) (1)
The difference between both optical control of l-type Ca 2 + channels using a diltiazem photoswitch (1)
Concise Stereoselective Routes to Advanced Intermediates Related to Natural and Unnatural Pinnaic Acid This work was supported by the National Institutes of Health (Grant Numbers: CA28824). Postdoctoral Fellowship support is gratefully acknowledged by M.W.C. (U.S. Army BCRP, DAMD17-98-1-8154), M.F.H (2001) (1)
Optical Control of Membrane Fluidity Modulates Protein Secretion (2022) (1)
Biomimetic Synthesis of (.+‐.)‐Pinnatal and (.+‐.)‐Sterekunthal A. (2003) (1)
Catalysis of 6p Electrocyclizations (2008) (1)
Development of a Friedel—Crafts Triflation. (2007) (1)
Selective Targeting of p38 MAPK Isoforms Using PROTACs (2019) (1)
Folate-Caged PROTACs Favor Cancer Cells (2021) (1)
Rolf Huisgen (1920–2020) (2020) (1)
Der Schattensammler. Die allerletzte Autobiografie. By Carl Djerassi. (2013) (1)
Concise Synthesis of (.+-.)-Smenochromene D (= Likonide B). (2005) (1)
An Efficient Synthesis of Tetrodotoxin (2021) (1)
Chapter 13 Biomimetic synthesis of natural products isolated from Bignoniaceae (2004) (1)
Bilirubin in einem neuen Licht (2013) (1)
PHOTACs Enable Optical Control of Protein Degradation. (2019) (1)
Microtubules coordinate protrusion-retraction dynamics in migrating dendritic cells (2019) (1)
Restoring Light Sensitivity in Blind Mouse Retinas With an AAQ Photoswitch Molecule (2010) (1)
Maleimides Allow for Cycloaromatization of Acyclic Enediynes (2020) (1)
Total Synthesis of Morphine- and Hasubanane Alkaloids (1997) (1)
Optical Control of the Peroxisome Proliferator-Activated Receptor γ (PPARγ) (2020) (1)
Concise Synthesis of the Bacterial DNA Primase Inhibitor (+)‐Sch 642305. (2007) (1)
Mapping light distribution in tissue by using MRI-detectable photosensitive liposomes (2022) (1)
Cover Image (2020) (1)
Author response: Optical manipulation of sphingolipid biosynthesis using photoswitchable ceramides (2019) (1)
Expanding the Toolbox of Synthetic Genetics (2021) (1)
Antimalarial 1,2,4-Triazine Dimers (2019) (1)
University of Birmingham Optical control of GPR40 signalling in pancreatic cells (2017) (1)
Biosynthetic Glycan Labeling (2022) (1)
A Robust Route towards Functionalized Pyrrolizidines as Precursors for Daphniphyllum Alkaloids (2014) (1)
Next Generation Opto-Jasplakinolides Enable Local Remodeling of Actin Networks (2022) (1)
Chrysomycin A and Derivatives against Multi-Drug-Resistant Tuberculosis (2020) (1)
Optical Modulation of Neurotransmission (2013) (1)
Hydroxychloroquine – An Antimalarial to Fight COVID-19? (2020) (1)
All Optical Platform for Parallel and Spatiotemporal Control of Neuronal Activity (2008) (1)
Optical Control of Insulin Release (2014) (1)
Kaliumkanäle: symmetrisch, selektiv und sensitiv (2003) (1)
Concise Synthesis of (.+-.)-Rhazinilam Through Direct Coupling. (2006) (1)
Restoring Photosensitivity In Blind Mice With Small Molecular Photoswitch Phenyl-ethyl Aniline Azobenzene Quaternary Ammonium (2012) (1)
SCOTfluors: Small, Conjugatable, Orthogonal, and Tunable Fluorophores (2019) (1)
PHOTACs enable optical control of targeted protein degradation (2020) (1)
Molecular Mechanisms of T Cell Signal Transduction Revealed by Super-Resolution Fluorescence Microscopy (2011) (0)
Structure-Guided Design of ABA Receptor Agonists for the Control of Plant Water Use (2019) (0)
C–H Activation and Decarboxylative Cross-Coupling of Carboxylic Acids (2019) (0)
A Synthesis of (.+-.)-Aplydactone. (2016) (0)
Sterically Shielded Heptamethine Cyanine Dyes with Enhanced Photophysical Properties (2020) (0)
Formation of Boron Enolates (2008) (0)
Synthesis of Human Interleukin-8 by Native Chemical Ligation (2019) (0)
Sanglifehrins and Analogs: Synthesis and Biological Evaluation of their Immunosuppressive Activity (2021) (0)
C–H Trifluoromethylation Enabled by a Combination of Decatungstate and Copper Catalysis (2020) (0)
Better Photoswitch, Better Photopharmacology (2021) (0)
Three Is All You Need – Photoredox/Nickel-Catalyzed Protocol to Chiral β-Alkyl-α-Arylated Carbonyls (2021) (0)
SCH79797: A Two-For-One Deal (2020) (0)
Reaction with Electrophilic Nitrogen Species (2008) (0)
Synthesis by Rearrangement of Allylic Alkoxides (2008) (0)
Synthesis of Shimalactone A (2008) (0)
Synthesis of (±)-Uvaridacol L: An Antiausterity Agent (2021) (0)
EC5026, an Analgesic Without the Addictive Potential of Opioids (2021) (0)
O-Alkylation and O-Silylation under Neutral Conditions (2008) (0)
E7766, a Novel Interferon Genes (STING) Agonist (2021) (0)
Expedient Synthesis of (.+‐.)‐Bipinnatin J. (2006) (0)
A Mild and General Synthesis of Substituted Anilines (2020) (0)
Organelle-Targeted Membrane Tension Probes (2019) (0)
Fighting Malaria with Endoperoxides (2021) (0)
Efficient Nazarov Cyclizations of 2‐Alkoxy‐1,4‐pentadien‐3‐ones. (2004) (0)
Synthesis, Configuration, and Activity of an Anti-inflammatory Resolving Agonist (2019) (0)
Drugging the Undruggable using Irreversible Covalent K-Ras G12C Inhibitors (2021) (0)
Author response: A family of photoswitchable NMDA receptors (2015) (0)
A Blood-Brain Barrier Penetrant Photooxygenation Catalyst for Aβ Degradation (2021) (0)
Unraveling Masked GPX4 Inhibitors (2020) (0)
Toward the Total Synthesis of Ansalactam A (I). (2014) (0)
Activatable Photosensitizers for Photodynamic Therapy (2019) (0)
First Simultaneous Removal of SIRT2 Deacetylase and Defatty-Acylase Activities with PROTACs (2020) (0)
A Rigid Vitamin Diet: Allenic derivatives of Vitamin D (2021) (0)
Author Correction: Optical control of L-type Ca2+ channels using a diltiazem photoswitch (2021) (0)
Selective Cannabinoid Type 2 Receptor Antagonists (2021) (0)
Highly Selective Insulin-Degrading Enzyme Inhibitors (2019) (0)
Photoswitchable Anion Carriers (2021) (0)
Optical control of the glucagon-like peptide-1 receptor allosteric site (2016) (0)
Inside Back Cover: Biomimetic Synthesis of Complex Flavonoids Isolated from Daemonorops “Dragon's Blood” (Angew. Chem. Int. Ed. 40/2017) (2017) (0)
Discovery and Characterization of a Diels–Alderase (2020) (0)
A Potent Preclinical Plasmodium Proteasome Inhibitor (2021) (0)
Catching Cathepsin X in the Act (2020) (0)
Spiro-Trycyclic Alkaloids as nAChR Antagonists (2021) (0)
Extreme Sulfur Species Mediate Cellular Uptake (2019) (0)
Chapter 3 Challenges and opportunities for optochemical genetics (2013) (0)
Freeze! Put your tRNAs up! (2021) (0)
Sulfonium Sugars with Antidiabetic Activities (2019) (0)
SPiDER-Killer-βGal: A Photosensitizer for Targeted Cell Ablation with Single-Cell Resolution (2019) (0)
Click Chemistry for the Synthesis of Azides (2019) (0)
Corrigendum: Exploring the Pharmacology and Action Spectra of Photochromic Open‐Channel Blockers (2013) (0)
Discovery Of Photochromic Ligands That Block Voltage-gated K+ Channels At The Internal TEA Binding Site (2009) (0)
Design and Synthesis of Bryostatin 1 Analogues (2021) (0)
Antimalarial Heterocycles: Tackling Chloroquine-Resistent Plasmodium falciparum (2021) (0)
Synthesis by Cleavage of Enol Esters and Ethers (2008) (0)
Lipid Tails Make the Difference! (2020) (0)
Eschenmoser Sulfide Contraction in the Synthesis of Kinase Inhibitors (2021) (0)
HPLC-Free Synthesis of Nucleoside Triphosphates (2019) (0)
Total Synthesis and Configurational Assignment of Mutanobactin D (2021) (0)
Acylation (Claisen Condensation) (2008) (0)
1O2 Self-Reporting Photosensitizer for Phototherapy (2021) (0)
Selenophosph(V)azanes as Transporters and Sensors (2019) (0)
Synthesis of (±)-Bipinnatin J (2006) (0)
Enantioselective Deprotonation of Symmetrical Ketones (2008) (0)
Chemically Induced Vinylphosphonothiolate Electrophiles for Thiol–Thiol Bioconjugations (2020) (0)
Biomimetic Synthesis of Natural Products Isolated from Bignoniaceae (2005) (0)
The First Selective Inhibitor of DCLK-1 (2020) (0)
A Fluorescent Probe for Thioredoxin Reductase (2019) (0)
Optical Control of Mitosis with a Photoswitchable Eg5 Inhibitor (2021) (0)
Orally Dosed Lipid-Lowering Peptide (2021) (0)
Pamiparib – A Promising PARP Inhibitor (2021) (0)
Wittig Reagents for Sulfenic Acid Ligation (2021) (0)
Optical Control of Cardiac Function (2019) (0)
Sucrose Analogues for Real-Time Imaging of Intracellular Plant Metabolism (2021) (0)
A Chiral Hydrindane Mimics Fatty Acid and Inhibits ToxT (2021) (0)
PEP-K: A New Reagent for the O-Phosphorylation of Alcohols (2020) (0)
Activity-Based Glycosidase Probes for Tumor Imaging (2021) (0)
Water-Soluble BODIPY Dyes for Voltage Imaging (2019) (0)
Versatile Thermoreversible Nucleic Acid Caging (2020) (0)
New Methods to Access DNA-Encoded Libraries (DELs) (2019) (0)
Photopharmacological tools to control cellular function with light (2016) (0)
Studies Towards the Total Synthesis of Halichlorine: Asymmetric Synthesis of the Spiroquinolizidine Subunit. (1999) (0)
A Far-Red Emitting IrIII-Complex–Coumarin Dyad for Photodynamic Therapy (2019) (0)
Conformational Restricted Cyclopropanated Nucleoside Derivatives (2019) (0)
Synthesis and Characterization of a Red-Shifted, Fast Relaxing, Photoswitchable Tethered Ligand for use in Modified Glutamate Receptors (2013) (0)
Synthesis of Variecolortides A and B (2011) (0)
Controlling the Covalent Reactivity of a Kinase Inhibitor with Light (2021) (0)
A First-in-Class, Clinically-Relevant Covalent Inhibitor of KRAS(G12C) (2020) (0)
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Replacing HN3 with Nitromethane for Schmidt-Type Formation of Amides and Nitriles (2020) (0)
Small-Molecule Inhibitor of an RNA-Modifying Enzyme for Acute Myeloid Leukemia Treatment (2021) (0)
Optical Control of CENP-E Function (2020) (0)
Cobalt-Catalyzed Asymmetric Hydrogenation of α,β-Unsaturated Acids (2020) (0)
Redirection of the Transcription Factor SP1 by Synthetic Molecules (2021) (0)
Targeting Myc through Stabilization of the Max Homodimer (2019) (0)
Serine-Selective Bioconjugation (2020) (0)
Transformation of Receptor Tyrosine Kinases into Glutamate Receptors and Photoreceptors (2020) (0)
Irreversible Covalent Inhibition of TrxR1 Prevents STAT3-Dependent Transcription Activation (2020) (0)
Expedient Synthesis of (+)‐Lycopalhine A. (2016) (0)
A Small-Molecule Inhibitor of C5 Complement Protein (2019) (0)
Synthesis of Taiwaniaquinoids (2007) (0)
CCDC 1475333: Experimental Crystal Structure Determination (2016) (0)
Covalent Inhibitors and Fluorescent Probes for Investigation of SARS-CoV-2 Mpro in Patient Samples (2021) (0)
Platform R : Channel Regulation & Modulation (2010) (0)
Broichhagen et al-Angewandte Chemie International Edition.sup-1 (2015) (0)
Synthesis of Azidoribose Probes to Track Ketoamine Adducts (2020) (0)
Reductive cyclization of delta-hydroxy nitriles: a new synthesis of glycosylamines. (2003) (0)
A Novel APJ Receptor Agonist through SAR Studies (2021) (0)
Reaction with Sulfur and Selenium Electrophiles (2008) (0)
A PROTAC for KRAS G12C Degradation (2020) (0)
Sulfuramidimidoyl Fluorides as SuFEx Electrophiles for the Inverse Drug Discovery of Covalent Drugs (2020) (0)
Staudinger Ligation in Living Animals (2019) (0)
Design and Synthesis of a Potent Spongistatin 1 Analogue (2019) (0)
Natural PDE4 Inhibitor Toddacoumalone (2020) (0)
Bioactive Analogues of TAN-2483B (2019) (0)
Reaction with Electrophilic Halide Reagents (2008) (0)
Workshops (2016) (0)
Orexin-1-Receptor-Selective Antagonists through Structure-Based Drug Design (2020) (0)
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The First FDA-Approved Antibody-Drug Conjugate (2020) (0)
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University of Birmingham Allosteric Optical Control of a Class B G-Protein-Coupled Receptor (2016) (0)
A Solid Way to Purify Polyethylene Glycols (2021) (0)
Concise Synthesis of Glycerophospholipids. (2022) (0)
Synthesis of Product Subclass 2 (2008) (0)
A Rapid Flow Synthesis of Linezolid (2019) (0)
Permeable and Fluorogenic Nanoscopy Probes (2020) (0)
Clickable UDP-Galactose Analogues (2020) (0)
TREK Channel Family Activator for Relief of Pain and Neurogenic Inflammation (2020) (0)
Beating Resistant Plasmodium Parasites with the Antimalarial MMV688533 (2021) (0)
Merging Indole and Morphan Fragments to Form Potent Glucose Transporter Inhibitors (2019) (0)
Synthesis and biological evaluation of (±)-hippolachnin and analogs (2019) (0)
Synthesis by Reduction of α-Halocarbonyl and Related Compounds (2008) (0)
In Vivo Optochemical Control of Glutamate Receptors with Cloaked Glutamates (2020) (0)
Macropinocytosis is Key to Peptidomimetic Uptake in Cancer Cells (2020) (0)
Non-Enzymatic Phospholipid Synthesis in Water (2021) (0)
Development of a Selective PI3Kγ Inhibitor (2021) (0)
Reaction on the C-Terminus with C-Electrophiles (2008) (0)
Total Synthesis of N14-Desacetoxytubulysin H Using Passerini Multicomponent Reaction (MCR) (2020) (0)
Synthesis of Chiral Tetramic Acids: Preparation of ( S )‐5‐Benzylpyrrolidine‐2,4‐Dione from L‐Phenylalanine Methyl Ester Hydrochloride (2020) (0)
Off-Switch Rapamycin (2021) (0)
LiGluR-Mediated Visual Responses in the Rodent Models of Inherited Blinding Diseases (2010) (0)
LYTACs for the Degradation of Secreted and Membrane Proteins (2019) (0)
Formation of Silyl Enol Ethers and Tin Enolates (2008) (0)
Classics in Stereoselective Synthesis . Von Erick M. Carreira und Lisbet Kvaerno. (2009) (0)
Palladium-Catalyzed Synthesis of Pyrimidine Nucleoside Analogs (2019) (0)
Antibiotics in a Trojan Horse (2021) (0)
Pentameric ligand gated ion channel GLIC in complex with tetramethylarsonium (TMAs) (2010) (0)
Glutathione-Sensitive Imaging and Targeted Drug Delivery (2021) (0)
Muxfeldt’s Synthetic Tetracycline Antibiotics (2021) (0)
Discovery and Total Synthesis of Anaenamides A and B (2020) (0)
Total Synthesis of Galactosyl-Queuosine (2020) (0)
Selective PI3Kγ Inhibitors for in vivo Studies (2021) (0)
Synthesis by Anionic Oxy-Cope Rearrangement (2008) (0)
Synthesis of Bridged 4′-Thio Nucleic Acid Monomers (2021) (0)
Synthesis of cis-Aminopiperidine by Asymmetric Hydrogenation (2021) (0)
How to Overcome Vancomycin Resistance (2020) (0)
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Ratiometric Fluorescent Sensing of Intracellular Potassium (2021) (0)
Visible-Light-Induced Arene Dearomatization Cascades (2020) (0)
Bright and Orthogonal NanoLuc Substrates (2020) (0)
Mild Hydrolysis of Enol Ketene Acetals or Enol Ortho Esters (2008) (0)
Utorubicin: A Novel Anthracycline Cancer Prodrug (2021) (0)
Phosphoglycolipids with Immunomodulatory Activity (2020) (0)
Total Synthesis of Heliolactone and its Biological Evaluation in Plants (2019) (0)
Evaluation of C2−C2′ Bond Stereochemistry Influence on Cytotoxicity of (–)-Lomaiviticin A (2021) (0)
Overcoming Vat Resistance with de Novo Synthesis of New Group A Streptogramin Analogues (2020) (0)
Introducing a Chiral Tricycle that Renders a Selective JAK Inhibitor (2020) (0)
A Photocatalytic Approach towards Cyclopentanonyl-Fused Cyclic Ethers (2021) (0)
Potent and Metabolically Stable Non-Opioid Analgesics (2019) (0)
Poppin’ Open Propellanes (2020) (0)
Comparison of second and third generation photoswitches in restoration of vision in blind mice (2015) (0)
Equilibration from the Corresponding Carbonyl Form (2008) (0)
In honor of Professor Samuel J. Danishefsky (2019) (0)
Novel Prodrugs for Targeted Cancer Therapy (2021) (0)
Fine-Tuning of Acid–Base Equilibria on the Synthesis of the Hexacyclic Core of Palau’amine (2021) (0)
Pyrrole Hemithioindigos: The New Photoswitch on the Block (2021) (0)
The First Total Synthesis of Lysergic Acid (2021) (0)
Chemical Protein Degradation Targeting Non-Functional Binding Sites (2019) (0)
Refining Selectivity of p38 MAP Kinase Inhibitors (2020) (0)
Catalytic eDHFR Acylation in HEK293T Cells (2021) (0)
PET Imaging of Alzheimer’s Disease With a 64Cu Multivalent Bifunctional Chelator (2021) (0)
Reversible Spatiotemporal Control of Induced Protein Degradation by Bistable PhotoPROTACs (2020) (0)
Should I Splay or Should I Stay - How Lipids and Transmembrane Helices Determine Membrane Fusion (2018) (0)
Bicyclic Sultams Made Easy (2019) (0)
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Transmetalation To Form Transition Metal Enolates and Zinc Enolates (2008) (0)
Aristoquinoline – A nAChRally Occurring Antagonist (2021) (0)
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Targeting the RAS–SOS1 Interaction (2019) (0)
Photocaged Antibiotics (2021) (0)
Protecting-Group Free Synthesis of (–)-Δ8-THC Derivatives (2019) (0)
Accelerating Aiolos Ablation (2020) (0)
Deprotonation with Organozinc Compounds (2008) (0)
Activity-Based Probe for Monitoring Ethylene (2021) (0)
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Characterization of Light-Controllable Polyamine Toxin Inhibitors of Ionotropic Glutamate Receptors (2014) (0)
Selective Electrochemical Benzylic C–H Functionalization (2020) (0)
Synthesis of Immunomodulatory Marine Natural Products (2001) (0)
Homo- and Hetero-FRET Imaging of Membrane Proteins in Live Cells (2011) (0)
RNA-Binding Protein Degradation with PROTACs (2021) (0)
Author Correction: Restoration of patterned vision with an engineered photoactivatable G protein-coupled receptor (2018) (0)
Optical Control of Sodium Channels (2021) (0)
Controlling Biological Pathways with Photopharmacology (2016) (0)
Prebiotic Link between RNA and DNA (2019) (0)
Total Synthetic Lankacidin Antibiotics (2020) (0)
Synthesis of Arimetamycin Hybrids (2021) (0)
Taking KRAS Inhibitors to the Clinic (2019) (0)
A Conversation with Gerhard Bringmann (2020) (0)
Reaction with S-Electrophiles: Formation of Enol Trifluoromethanesulfonates (2008) (0)
Electrocyclizations of 8π Systems (2011) (0)
Mapping the Chemistry of Highly Unsaturated Pyrone Polyketides. (2006) (0)
On-Demand Synthesis of Modified Oligonucleotides (2021) (0)
Investigating TRPA1 Modulation with Noncovalent Piperidine Carboxamide Based Binders (2020) (0)
Electrocyclizations of 6π Systems (2011) (0)
Click-Chemistry Based Enrichment Strategy Extends the Detectable Metabolome in LC-HRMS/MS Analysis (2020) (0)
Cleavage of Enol Esters (2008) (0)
Macrodiolide Library Synthesis of cGAS-STING Inhibitors (2021) (0)
Synthesis by Nucleophilic Addition to Ketenes (2008) (0)
Macrocycle Library Synthesis through Thiol-to-Amine Cyclization (2019) (0)
Profiling of Inhibitor-Bound Kinase Complexes (2019) (0)
Ligand-gated Channels: Glutamate Receptors (2009) (0)
Uncaging Ligands using Bioluminolysis (2021) (0)
α-Ketoamide Inhibitors of SARS-CoV-2 Main Protease (2020) (0)
Bifunctional Ligands of K-Ras Prevent the Recruitment of BRAF in vitro (2019) (0)
A Nimbolide-Derived PROTAC (2019) (0)
Synthetic Cystobactamid Antibiotics With Improved Activities (2020) (0)
Optical Control of CAR-T Cell Function (2021) (0)
Torgov Cyclization (2019) (0)
No Strain-No Gain: Adducts of Strain-Release Povarov Reaction Against Multidrug-Resistant Persister Bacteria (2021) (0)
Membrane Photoswitches on Neuronal Fire (2020) (0)
Reaction of Enolates on the C-Terminus with Electrophilic Heteroatom Species (2008) (0)
Goyazensolide, a Covalent Importin‑5 (IPO5) Inhibitor (2021) (0)
Water-Soluble Benzene Mimetics (2020) (0)
The Conformations of Halichlorine (I) and the Pinnaic Acids (II): Nitrogen Inversion as a Possible Determinant of Biological Profile. (2000) (0)
Unleashing the Full Power of the Streptavidin–Biotin Technology in Cellular Uptake (2020) (0)
Synthesis of Dienes through Electrocyclic Ring Opening of Cyclobutenes (2011) (0)
Peptide Antagonist of CGRP Receptor for Migraine Treatment (2020) (0)
A Mild Method to Access Various Sulfur(VI)-Fluorides (2020) (0)
A Carbapenemase Probe that Switches on the Light (2020) (0)
Labeling of Tetrazines with Spatiotemporal Precision (2019) (0)
Biomimetic Synthesis of Elysiapyrones A (I) and B (II). (2005) (0)
Pyrazolopyrimidines: Molecular Correctors for MALT1-Related Immune Defects (2019) (0)
Light-Induced Cell Cycle Arrest and Apoptosis (2021) (0)
Deprotonation and Subsequent Reaction as an Enolate (2008) (0)
Agnostic Screening of Sulfonyl Fluoride Fragments to Generate Selective Covalent Inhibitors (2019) (0)
Palladium-Catalyzed Couplings to Nucleophilic Heteroarenes: The Total Synthesis of (-)-Frondosin B. (2005) (0)
A Highly Selective Inhibitor of TBK1/IKKε (2020) (0)
Selective Activation of Protein Phosphatase 2A Complexes (2020) (0)
A Photocrosslinkable Mycobacteria Glycolipid Probe (2020) (0)
Biomimetic Synthesis of Elysiapyrones A and B (2005) (0)
BET Bromodomain Inhibitors Promote Wound Healing (2021) (0)
A Brain-Penetrant mTOR Kinase Inhibitor for the Treatment of Neurological Disorders (2021) (0)
Doubly Caged Puromycin (2021) (0)
Dual Inhibitors of OGG1/NUDT1 for Probing Disease States (2020) (0)
Introducing Phosphatase-Recruiting Chimeras (2020) (0)
Restoration of light sensitivity to blind mice with red-shifted chemical photoswitches (2013) (0)
Complex Natural Products Derived from Pyrogallols. (2022) (0)
Synthesis by Deprotonation (2008) (0)
Late-Stage Epoxidation of Geldanamycin with Peptide-Based Organocatalysts (2020) (0)
Clickable FPP/GGPP Analogues Enable Analysis of Prenylome (2019) (0)
Protonation and Deuteration of Enolates (2008) (0)
Electrocyclizations of Hexatrienes and Octatetraenes (2011) (0)
Synthesis and Biological Evaluation of Macrocyclic Δ12-Prostaglandin J2 Analogues (2019) (0)
Cover Image (2019) (0)
Synthesis of Five-Membered Rings through Electrocyclization of Pentadienyl Cations: The Nazarov Cyclization (2011) (0)
Truncated Mycalolide B Analog to Prevent Cancer Metastasis (2021) (0)
Concise Total Synthesis of (‐)‐Frondosin B Using a Novel Palladium‐Catalyzed Cyclization. (2002) (0)
Discovery of a CNS-Active Inhibitor of NAPE-PLD (2020) (0)
Photocatalyzed Site-Selective Tyrosine Bioconjugation (2021) (0)
Targeting Zinc Homeostasis in Cancer (2019) (0)
A Long-Lasting HIV-Capsid Inhibitor (2020) (0)
A Silicon-Based Pain Killer ‘Sila-Ibuprofen’ (2020) (0)
Design and Synthesis of a Selective CDK7 Covalent Inhibitor (2019) (0)
Author Correction: Restoration of patterned vision with an engineered photoactivatable G protein-coupled receptor (2018) (0)
Cell-Type-Specific Voltage Imaging Using Covalently Tethered Fluorophores (2020) (0)
Late-Stage 18F Incorporation with Photoredox Catalysis (2019) (0)
Transition-Metal-Catalyzed Isomerization of Allylic Alcohols (2008) (0)
Selective α-Glycosidation of Sialic Acid (2019) (0)
A Potent and Selective Covalent Inhibitor of Pin1 (2020) (0)
Improved Fluorogenic Dye-Aptamer Module for Live-Cell RNA-Imaging (2019) (0)
Synthesis of (-)-Heptemerone B (2007) (0)
CCDC 1475334: Experimental Crystal Structure Determination (2016) (0)
Photoactivated Fluxional Fluorophore Enables Extended Time-Lapse Microscopy (2019) (0)
Sulfo-Click Conjugation (2020) (0)
Deprotonation under Thermodynamic Conditions (2008) (0)
On the Simulated Interplay of External Friction and Thermo-Fluid Dynamics of Glas-Fibre-additivated Polymeric Melt in the Backflow Barrier of a Screw Extruder (2018) (0)
Non-nucleotide cGAMP Mimetics with Powerful Antitumor Activity (2020) (0)
A Small Clickable and Photoconvertible Fluorophore (2019) (0)
Introducing Phosphorylation-Inducing Chimeric Small Molecules (PHICS) (2020) (0)
Discovery of New Chemotypes by Deep Screening of an Ultra-large Virtual Library (2019) (0)
Engelhardt’s Deoxofluorination 60 Years Later (2020) (0)
Synthesis of AWZ1066S, an anti-Wolbachia Drug Candidate (2019) (0)
In vivo Engineering of Light Sensitive Neurons in the Diseased Retina (2006) (0)
The First Total Synthesis of Artemisinin (Qinghaosu) (2019) (0)
Potent and Selective Acid Sphingomyelinase Inhibitors with Antidepressant Activity (2020) (0)
Next-Generation Macrolide Antibiotics (2021) (0)
One, Two, Three – Nucleosides (2020) (0)
Photoswitchable Gramicidin S Derived β‑Hairpin Peptides (2019) (0)
Defying the Odds – Drugging KRAS (2019) (0)
Identification of ENL YEATS Domain Inhibitors through Cell-Based Drug Discovery with SuFEx (2021) (0)
Cover Picture: Biomimetic Total Synthesis of Santalin Y (Angew. Chem. Int. Ed. 17/2015) (2015) (0)
Inhibition of the Pentose Phosphate Pathway Reveals its Importance in the Immune Response (2020) (0)
Total Synthesis and Structure-Activity Studies of Geodiamolide H (2021) (0)
Synthesis and Application of the 3-Phosphonofluoresceins (2021) (0)
Design and Synthesis of Antiviral Drug Candidates Targeting SARS-CoV-2 Main Protease (2020) (0)
A Vincamine-Derived HCRTR2 Agonist Prevents Morphine-Seeking Behavior in Mouse Models (2020) (0)
Engineering light-gated glutamate receptors (2009) (0)
Structure activity relationship studies of newly synthesized larixol derivatives as potent TRPC6 inhibitors (2016) (0)
Synthesis of (±)-Rhazinilam (2006) (0)
Discovery of LYS006, an Inhibitor of Leukotriene A4 Hydrolase for the Treatment of Inflammatory Diseases (2021) (0)
The First Total Synthesis of Cocaine (2021) (0)
Targetable, Bright Small-Molecule Ca2+ Indicators (2019) (0)
Total Synthesis of (-)-SNF4435 C (I) and (+)-SNF4435 D (II). (2006) (0)
Diversity-Oriented Synthesis of Acylphloroglucinol Scaffolds (2020) (0)
Development of Light Activated LXR Agonists. (2023) (0)
The First Contraceptive (2020) (0)
Synthesis of Nucleoside Oligophosphates: Quick and Not Dirty (2019) (0)
A structural link between potassium channel gating and drug binding. (2008) (0)
Stereostructure–Activity Studies of Spirooliganin (2021) (0)
Selectively Binding a Bromodomain (2020) (0)
A Highly Selective and Potent Small-Molecule Inhibitor of Factor B (2019) (0)
Light At The End Of The Channel: Photochromic Blockers For Optical Control Of Ion Channels In Individual Cells (2009) (0)
Straight to the Heart of the Problem: Factor XIa Inhibitor for Antithrombotic Therapy (2021) (0)
Photoinduced Electron Transfer for the Selective Labeling of Tryptophan Residues (2020) (0)
Small-Molecule Inhibitors of CRISPR-Cas9 (2019) (0)
Gram-Scale Synthesis of Iboxamycin (2021) (0)
A Synthetic Diterpene Against Persistent Mycobacteria and Biofilm Formation (2021) (0)
Targeted Degradation of Extracellular Proteins with ENDTACs (2019) (0)
Ring-Closing Metathesis in the Synthesis of Simeprevir (2019) (0)
Late-Stage Negishi Coupling of Peptides (2019) (0)
Double Deprotonation of a 1,4-Dicarbonyl Compound (2008) (0)
A Novel and Highly Selective FAK Inhibitor (2021) (0)
Synthesis of ‘Stretched’ Isosteres of Saturated Nitrogen Heterocycles (2019) (0)
Chemoselective Cross-Coupling Reactions on Pyridine Derivatives (2020) (0)
Synthesis of Aglaroxin C Analogues for Hepatitis C Viral Infection Inhibition (2019) (0)
A Classic Way of Forming Amide Bonds (2020) (0)
Thermal Proteome Profiling Identifies the Target of Indophagolin (2021) (0)
A Manganese-Based Contrast Agent for Imaging Calcium Ions (2019) (0)
Stable Colibactin Analogues Enable Mechanism of Action Studies (2021) (0)
Light-Controlled Carbonation (2020) (0)
Reaction with Oxygen Electrophiles (2008) (0)
Concise Synthesis of Deoxygenated Sugar (2021) (0)
Two-Stage Photocatalytic Diamination of Alkenes (2020) (0)
Kinetic Deprotonation of a Ketone (2008) (0)
Diversity-Focused Semisynthesis of Polyether Ionophores with New Antibacterial Selectivity (2021) (0)
A Hydrolytically Stable Analog of Decitabine (2019) (0)
Restoring Light Sensitivity in Blind Retinae using Third Generation Photopharmacology (2015) (0)
A Broadly Reactive Covalent Ligand for Glutamates and Aspartates (2020) (0)
A Toxic RNA Makes Its Own Fluorescent Inhibitor (2020) (0)
Author response: Manipulating midbrain dopamine neurons and reward-related behaviors with light-controllable nicotinic acetylcholine receptors (2018) (0)
Design, synthesis, and biological evaluation of photoswitchable Eg5 inhibitors (0)
cGAS/STING Antagonist Discovered in Butenolide Dimer Library (2020) (0)
Stronger Together! (2020) (0)
pH-Sensitive μ Opioid Receptor Agonists (2019) (0)
Photocatalytic Defluoroalkylation of Unactivated Trifluoromethylarenes (2019) (0)
A Sensor for Attomolar Copper Levels (2019) (0)
Development of Small-Molecule ENPP1 Inhibitors (2021) (0)
Total Synthesis of (-)-Heptemerone B (I) and (-)-Guanacastepene E (II). (2007) (0)
Near-IR Polymethine Fluorophores Absorbing Beyond 1000 nm (2019) (0)
Postsynthetic Photocontrol of Giant Liposomes via Fusion-Based Photolipid Doping (2022) (0)
Stereoselective Covalent Inhibitors of T-Cell Activation (2020) (0)
Crystal Structure of the Main Protease of Human Coronavirus NL63 (2020) (0)
A Nucleolus-Targeted, Photocaged Pt(IV) Prodrug Overcomes Cancer Resistance (2020) (0)
The Chemistry of Marine Furanocembranoids, Pseudopteranes, Gersolanes, and Related Natural Products (2008) (0)
A Mitochondria-Targeting Calcium Dye (2019) (0)
Go Bi-Steric for Selectivity (2021) (0)
DNA-Compatible Conversion of Primary Amines into Azides (2020) (0)
Enantiomeric Probe Pairs for Ligandable Proteome Mapping (2019) (0)
Interrupted Nazarov Cyclizations (2011) (0)
A Practical Variant of the Claisen—Eschenmoser Rearrangement: Synthesis of Unsaturated Morpholine Amides. (2002) (0)
Crystal structure of (E)-1,2-bis(4-bromo-2,6-difluorophenyl)diazene (2015) (0)
Stereoselective Insertion of Ketenes into O,O-Acetals: Synthesis of . beta.-Alkoxyesters and 1,4-Dioxepan-5-ones. (2010) (0)
Sarin and Other G-Series Nerve Agents (2020) (0)
Reducing the Risk of Opioid Misuse (2021) (0)
Exploring Biosynthetic Relationships Among Furanocembranoids: Synthesis of (-)-Bipinnatin J (I), (+)-Intricarene (II), (+)-Rubifolide (III), and (+)-Isoepilophodione B (IV). (2007) (0)
Radical Difluorination (2020) (0)
Styrylbenzothiazoles – A New Class of Photoswitches (2021) (0)
Controlling the Actin Cytoskeleton with Light (2020) (0)
O-Alkylation and O-Acylation To Form Enol Ethers and Enol Esters (2008) (0)
Efficient Multigram Synthesis of Dibenzoazacyclooctyne for Strain-Promoted Alkyne–Azide Cycloadditions (2020) (0)
Novel Antibiotics by Late-Stage Derivatization of Marketed Fidaxomicin (2021) (0)
4-Aminoquinazolines as Potent Inhibitors of the G Protein-Coupled Receptor Kinase 6 (GRK6) (2021) (0)
Light Control of Cell Excitability Using a Photochromic Blocker for Voltage-Gated Ion Channels (2010) (0)
Photoredox Conjugate Addition Allows Access to a New Class of LRH-1 Agonists (2020) (0)
A glimpse at the grail (2005) (0)
Umibecestat, A Highly Selective β‑Secretase (BACE1) Inhibitor (2021) (0)
Sticking a Label on Tyrosine (2020) (0)
An Asymmetric [3+2] Cycloaddition/Ring-Expansion Sequence Towards Lysergic Acid (2021) (0)
Catalytic Nazarov Cyclizations (2011) (0)
Dual Inhibitors of Anaplastic Lymphoma Kinase and Bromodomain‑4 (2019) (0)
Ethynylphosphonamidates in the Synthesis of Antibody–Drug Conjugates (2019) (0)
The Next Generation Lincosamide: Iboxamycin (2021) (0)
Stereoselective Syntheses of the Bioactive Polypropionates Aureothin, N‐Acetylaureothamine, and Aureonitrile. (2005) (0)
Bioluminescence Seeing Red (2020) (0)
Synthesis by Base-Induced Rearrangement of Epoxides (2008) (0)
Lasonolide A is a Prodrug Activated by LDAH, a Serine Hydrolase (2020) (0)
Design and Application of a Light-Activated Metabotropic Glutamate Receptor for Optical Control of Intracellular Signaling Pathways (2011) (0)
Protein−Protein Cross-Coupling with an Electrophilic Palladium Reagent (2020) (0)
An Improved Photocaged Puromycin (2019) (0)
An Eight-Step Synthesis of Islatravir (2020) (0)
Constitutive activation and trafficking of the glucagon-like peptide-1 receptor using tethered pharmacology (2017) (0)
In vivo Visualization of Copper(II) in the Brain (2019) (0)
Reaction with Electrophilic Sulfur and Selenium Species (2008) (0)
The Total Synthesis of (‐)‐Nitidasin. (2015) (0)
A Glutathione-Labile Oligonucleotide Protecting Group (2019) (0)
Cortical Responses Driven by an Engineered Light Activated Glutamate Receptor in Models of Inherited Blinding Diseases (2009) (0)
CDFA contract number 08-0170 Project Title : Exploiting pathogen signal molecules for control of Pierce ’ s Disease (2010) (0)
Pentameric ligand gated ion channel GLIC in complex with cadmium ion (Cd2 (2010) (0)
Comparative STM study of azobenzene derivatives on bare and insulator coated metal surfaces (2006) (0)
Bioinspired Nucleobase Caging (2020) (0)
The First Synthesis of Morphine (2021) (0)
Remodeling of lipid rafts by photoswitchable ceramides characterized under high-speed AFM (2017) (0)
Synthesis of a Fluorescent Probe for Cell Surface Phosphatidylserine (2019) (0)
Pentameric ligand gated ion channel GLIC mutant E221A in complex with tetraethylarsonium (TEAs) (2010) (0)
Staudinger Reduction-Activated Lysine for the Control of Protein Subcellular Localization and SUMOylation (2020) (0)
A Novel Covalent Bruton’s Tyrosine Kinase Inhibitor (2021) (0)
Total Synthesis of Smenochromene B Through Ring Contraction. (2007) (0)
Versatile One-Step Approach to Caged Fluorophores (2019) (0)
Structure-Guided Discovery of Selective Mcl-1 Inhibitors (2019) (0)
Late-Stage Functionalization of Complex Primary Sulfonamides via NHC Catalysis (2019) (0)
Author Correction: Natural product anticipation through synthesis (2022) (0)
Protein Synthesis on Demand, and Make it Snappy! (2020) (0)
Chemoselective Methionine Bioconjugation in the Synthesis of Antibody Drug Conjugates (ADCs) (2020) (0)
Transmetalation with Organotitanium or Organozirconium Complexes (2008) (0)
Reaction with Carbon Electrophiles under Neutral or Acidic Conditions (2008) (0)
C–N Coupling of Aryl Thianthrenium Salts (2019) (0)
Total Synthesis of a Gene (2020) (0)
Presaccharothriolide Z, an (E)-Enone-Containing, 10-Membered Macrolactone (2021) (0)
Handy Thioethers: Biotin-Derived Sulfimides as Protein and DNA Labeling Tools (2021) (0)
Site-Selective LYTACs for Targeted Protein Degradation (2021) (0)
BromoTag – A ‘Bump-and-Hole’ PROTAC System (2021) (0)
Hapten Deuteration of a Heroin Vaccine (2020) (0)
Synthesis of Microphyllaquinone (2006) (0)
Targeting Transcription Factors for Degradation (2021) (0)
Characterization of Photoswitchable Sodium Channel Inhibitors by Planar Patch Clamp (2018) (0)
Modification of Phosphinopeptidic Scaffolds by Giese-Type Alkylation (2019) (0)
Discovery of Soticlestat, a Potent and Selective Inhibitor for Cholesterol 24-Hydroxylase (CH24H) (2021) (0)
Cell Type-Selective Secretome Profiling In Vivo (2021) (0)
The First SHP2 PROTAC (2020) (0)
Taking Bicycles on a New Ride (2021) (0)
Sign-Inversion in Photopharmacology (2019) (0)
Total Synthesis of (.+‐.)‐Photodeoxytridachione Through a Lewis Acid Catalyzed Cyclization. (2003) (0)
Short Synthesis of the 3-Deazaguanosine RNA Building Block (2019) (0)
Salinipostin A Probe Identifies Potential Antimalarial Protein Targets (2020) (0)
Chemical Microbiology and Synthesis Reveals the Structure of Colibactin and its Mode of Genotoxicity (2019) (0)
Optical Control of CRAC Channels (2020) (0)
Copper Sensing by Electrophile Activation (2020) (0)
Biosynthetic Engineering of Polyketide Synthase Modules Towards New Enacyloxin Antibiotics (2020) (0)
Potent and Selective Orphan GPCR Agonist for the Treatment of Schizophrenia (2021) (0)
Neurology-important advances in clinical medicine: the role of valproic Acid in the management of seizure disorders. (1982) (0)
6-Aza-artemisinins as Potent Antimalarial Drugs (2020) (0)
Total Synthesis of (.+‐.)‐Rhazinal (IXb) Using Novel Palladium‐Catalyzed Cyclizations. (2009) (0)
An in Vivo Mass Cytometry Probe for Protein Translation (2019) (0)
Pentameric ligand gated ion channel GLIC in complex with Br-lidocaine (2010) (0)
A New Class of Stimulator of Interferon Genes Receptor Agonists (2019) (0)
Janelia Fluor Photosensitizers (2020) (0)
Crocipodin (I), a Benzotropolone Pigment from the Mushroom Leccinum crocipodium (Boletales). (2011) (0)
Optical Control of Gene Silencing by Azobenzene-Modified siRNA (2020) (0)
Applications of Product Subclass 1 in Organic Synthesis (2008) (0)
Biomimetic Synthesis of (.+-.)-Merochlorin B. (2014) (0)
Pumping and Probing for the Optimal Dienophile (2020) (0)
Concise Synthesis of the Novel Spliceosome Inhibitor H3B-8800 (2021) (0)
Local Labeling of Lipids (2020) (0)
New Ventures in the Construction of Complex Heterocycles: Synthesis of Morphine and Hasubanan Alkaloids. (1998) (0)
Organophotoredox-Catalyzed Sulfoximidation of Electron-Rich Arenes (2019) (0)
Synthetic Approaches Toward Sesterterpenoids (2012) (0)
Progesterone from Mexican Yams (2020) (0)
Toward Catalytic Antibiotics (2021) (0)
Total Synthesis of (+)‐Halichlorine: An Inhibitor of VCAM‐1 Expression. (2010) (0)
Functionalization of Palladium Oxidative Addition Complexes Derived From Pharmaceuticals (2019) (0)
Protein Modification by Cope Rearrangement (2020) (0)
Optical Control of the Cannabinoid Receptor 2 (2021) (0)
A High Affinity Fluorescent Sensor for Norepinephrine (2019) (0)
Visualizing Prostate Cancer with Activatable Fluorophores (2019) (0)
Synthesis of Photo-Caged ATP (2020) (0)
Remote control of glucose homeostasis in vivo using photopharmacology (2017) (0)
Targeted Tumor Therapy via Extracellular Calcification (2021) (0)
Four New DNA Building Blocks (2019) (0)
Development of Fluorescent Ca2+ Sensors (2019) (0)
To Isomerize or not to Isomerize? E /Z Isomers of Cyclic Azobenzene Derivatives and their Reactivity upon One-Electron Reduction. (2023) (0)
Fluorophores, Get On My Nerves! (2020) (0)
Shocking Selectivity for Hsp90α (2021) (0)
Synthesis of a cGAMP Analogue (2019) (0)
Synthesis of the Smallest Cyclodextrins (2019) (0)
Application of Hemithioindigo Photoswitches in Photopharmacology (2019) (0)
Enantioselective Diacetoxylation of Terminal Alkenes (2021) (0)
A Positive Allosteric Modulator of the Human Dopamine D1 Receptor (2019) (0)
Membrane Probes for Super-Resolution Imaging of Plasma Membranes (2019) (0)
Infrared hole burning and conformational change in a borane-ammonia complex. (2005) (0)
Beta Cell Hubs Dictate Pa ncreatic Islet Responses to Glucose Graphical Abstract Highlights (2016) (0)
Hygromycin A Finds a New Purpose (2021) (0)
Electrochemical Synthesis of Oxygenated Dihydrofurans (2005) (0)
Bioinspired Synthesis of (−)‐PF‐1018 (2020) (0)
The Gram-Negative Upgrade for Ribocil C (2020) (0)
Ethynylphosphonamidate-Cysteine Bioconjugation (2019) (0)
Total Synthesis of Epicoccine and Its Dimerization to Dibefurin (2015) (0)
Total Synthesis of Cephalosporin C (2021) (0)
Depalmitoylation Strategy to Inhibit NRAS Signaling (2020) (0)
Binding-Site Hotspot Mapping using Photochemical Proteomics (2019) (0)
Seven-Step Synthesis of (–)-Colchicine (2021) (0)
Synthesis by Conjugate Addition (2008) (0)
PEARL-seq: A Workflow for Analyzing Small Molecule–RNA Interactions (2020) (0)
Zinc Bis(hexamethyldisilazide) (2008) (0)
6-[6-(Pyridin-2-yl)-1,2,4,5-tetrazin-3-yl]pyridin-3-amine monohydrate (2016) (0)
Synthesis of the First FDA-Approved HIV Protease Inhibitor (2020) (0)
Total Synthesis of (-)-Archazolid B (I). (2007) (0)
Chemical Diversification of Pleuromutilin (2019) (0)
Development of an Iron(II)‐Catalyzed Aerobic Catechol Cleavage and Biomimetic Synthesis of Betanidin. (2015) (0)
Synthesis of Fluorinated Nucleoside Analogs with Antiviral Activity (2019) (0)
A Better Version of Rhodamine Voltage Reporter by ‘Trapping‘ (2021) (0)
Structural Modification of Oridonin Yields A More Potent Anticancer Agent (2020) (0)
Innenrücktitelbild: Biomimetische Synthese komplexer Flavonoide isoliert aus Daemonorops -“Drachenblut” (Angew. Chem. 40/2017) (2017) (0)
Stoichiometric Nazarov Cyclizations (2011) (0)
Berichtigung: Totalsynthese von Coralloidolid A, B, C und E (2015) (0)
Covalent Inhibitors for PIP Signaling (2020) (0)
Cleavage of Silyl Enol Ethers (2008) (0)
Titelbild: Biomimetische Totalsynthese von Santalin Y (Angew. Chem. 17/2015) (2015) (0)
A Novel P(V)-Based Reagent for Asymmetric Synthesis of Thiophosphoramidates (2021) (0)
A Photochemical Switch for Conferring Light Sensitivity Onto Endogenous Ion Channels and Retinal Neuron Firing (2007) (0)
Reductive Cyclization of δ‐Hydroxy Nitriles: A New Synthesis of Glycosylamines. (2003) (0)
Spirocyclic Ketone Construction via Semipinacol-Type Rearrangement (2021) (0)
A Photosensitive Cyclic Acetal Enables Efficient Photo-release of 1,3-Diol 2-Arachidonoylglycerol (2019) (0)
Hindered Dialkyl Ether Synthesis Electrified (2019) (0)
A Fluorinated Carbocyclic Nucleoside with Anti-HBV Activity (2019) (0)
A Tool to Observe Cellular Apposition (2020) (0)
Transmetalation with Nickel(II) or Palladium(II) Complexes (2008) (0)
Synthesis of (-)-Bipinnatin J and (+)-Intricarene (2007) (0)
Photocaged Dopamine Receptor Ligands (2020) (0)
How to Repurpose Sanger’s Reagent as a Photocage (2020) (0)
Scalable Synthesis of Opioids Enabled by a Palladium-Catalyzed Dearomative Arylation (2021) (0)
Late-Stage Alkylation of Purine Nucleoside at the C6 Position (2021) (0)
A Reagent for Doubly Bioorthogonal Cysteine Labeling (2019) (0)
Reaction with Nitrogen Electrophiles (2008) (0)
Optimizing Triarylborane Fluorophores for Biological Applications (2019) (0)
Caged Aptamers for Improved Cancer Imaging (2020) (0)
The Woodwardian Synthesis of Erythromycin A (2021) (0)
Efficient Total Synthesis of Lipid I and Lipid II Analogues (2020) (0)
Assessment of GSK2798745 Metabolite (2021) (0)
A Protecting Group Orchestration Enables Modular Access to Libraries of Heparan Sulfate Oligosaccharides (2020) (0)
Synthesis of acremines A, B and F and studies on the bisacremines (2019) (0)
Modular, Targeted IDO Inhibitor for Cancer Immunotherapy (2020) (0)
Somatic nicotinic acetylcholine receptors control the activity of dopamine neurons and reward-related behaviors (2018) (0)
Oxidative Dimerization of Enolates and Related Oxidative Couplings (2008) (0)
Biosynthetic and Biomimetic Electrocyclizations (2006) (0)
Biomimetic Total Synthesis of Santalin Y. (2015) (0)
Medium-Length Lipids Facilitate Cell-Permeability and Bioactivity (2021) (0)
Keep in Mind: An Oxadiazine as Gamma Secretase Modulator for Treating Alzheimer’s Disease (2021) (0)
Photocontrol of a Membrane Nanopore Forming Protein (2019) (0)
Multiple Macrocyclization Strategies in the Syntheses of Potent Myeloperoxidase (MPO) Inhibitors (2021) (0)
Pentameric ligand gated ion channel GLIC in complex with tetrabutylantimony (TBSb) (2010) (0)
Copper-Catalyzed ortho-Radiofluorination of Aromatic C–H Bonds (2019) (0)
Synthesis of Cyclobutenes through Electrocyclization of Dienes (2011) (0)
Taking Two Monopolar Spindle 1 Kinase Inhibitors to Clinical Trials (2020) (0)
MicroMap: Precise Proximity Labeling of Cell Surface Proteins (2020) (0)
Vinyl Quinones as Diels—Alder Dienes: Concise Synthesis of (‐)‐Halenaquinone (III) (2008) (0)
X-ray Irradiation Promoted Activation of Prodrugs (2021) (0)
A Potential anti-Pertussis Vaccine Based on Lipopolysaccharide Endotoxins of B. pertussis (2020) (0)
Adding Oxygen with N-Ammonium Ylides (2021) (0)
PHOTO-INDUCED RELEASE OF AN ACETYLCHOLINESTERASE INHIBITOR (2018) (0)
Design and Development of Dual 5-HT3R/5-HT6R Antagonists (2021) (0)
RIBOTACs – Targeted Degradation of RNA (2020) (0)
Synthesis by Conjugate Reduction (2008) (0)
Biochemical , structural and functional study of ELIC probed with cysteine-reactive benzodiazepine analogs (2012) (0)
Sphingosine-1-phosphate Photopharmacology (2019) (0)
SYK Inhibitor with Improved hERG-Profile (2020) (0)
To Die or Not to Die – Inhibition of Apoptosis (2019) (0)
Total Synthesis of Pyrrolylpyrromethane Alkaloids with Antimalarial Activity (2021) (0)
Next Generation Vancomycin Total Synthesis (2020) (0)
In Vivo Imaging of Glucose Uptake (2019) (0)
An Aromatic Brønsted Acid Catalyst for the Direct Glycosylation of Amides (2019) (0)
Late-Stage Radiolabeling Enabled by SuFEx (2021) (0)
Development of Novel Lewis Acid Catalyzed Cycloisomerizations: Synthesis of Bicyclo[3.1.0]hexenes and Cyclopentenones. (2004) (0)
Influenza Drug Evades Resistance (2019) (0)
Photoswitchable Molecular Glues Enable Optical Control of Transcription Factor Degradation (2023) (0)
Dibromoacetone as an Efficient Linker for Protein Ubiquitination (2021) (0)
Pentameric ligand gated ion channel GLIC in complex with zinc ion (Zn2 (2010) (0)
Structure of GluK2-LBD in complex with GluAzo (2013) (0)
Natural-Product-Inspired Covalent Telomerase Inhibitors (2020) (0)
Covalent Suppression of the Cellular HDM2/p53 Protein-Protein Interaction using NASA (2021) (0)
Bioinspired Histidine Bioconjugation (2019) (0)
Human carboanhydrase F131C_C206S double mutant in complex with SA-2 (2017) (0)
A New Generation of Molecular Imaging Probes for Carbon Monoxide Detection in Living Systems (2020) (0)
Synthesis of Product Subclass 1 (2008) (0)
Inhibition of Mitochondrial Transcription (2021) (0)
Synthesis of Exiguamine A (2009) (0)
EXPLOITING PATHOGEN SIGNAL MOLECULES FOR CONTROL OF PIERCE'S DISEASE Principal Investigator (2009) (0)
A Repurposed Chemotherapy Drug as C1 Synthon (2020) (0)
Applications of Product Subclass 2 in Organic Synthesis (2008) (0)
Biphenyl Imidazopyridines as a New Scaffold for PD-L1 Inhibitors (2021) (0)
Targeting Mutant BRAF with PROTACs (2021) (0)
Elucidating the origin of preuisolactone A via biomimetic synthesis (2020) (0)
Restoration of patterned vision with an engineered photoactivatable G protein-coupled receptor (2017) (0)
The Total Synthesis of (-)-Amathaspiramide F (I). (2003) (0)
Bicyclic Arginase Inhibitors to Enhance Cancer Immunotherapy (2020) (0)
KEAP on Searching for Novel E3 Ligases (2021) (0)
The First Method to Sequence DNA (2019) (0)
Dansyl’s First Dance (2020) (0)
Discovery and Synthesis of Monastrol (2019) (0)
Human carbonic anhydrase II G132C_C206S double mutant in complex with SA-2 (2017) (0)
Assembling the carbon skeleton of A-74528 (2022) (0)
Azithromycin – An Antibiotic to Fight COVID-19? (2020) (0)
Covalent Inhibition of Ras G12C with a Stapled Peptidomimetic (2020) (0)
Optopharmacological tools for precise spatiotemporal control of oxytocin signaling in the central nervous system and periphery (2022) (0)
Watching RNA Do Its Job (2021) (0)
A New Approach for the Synthesis of Covalent Inhibitor Libraries (2021) (0)
Chemically Induced Dimerization (2020) (0)
Morpholine Analogues of Zampanolide (2020) (0)
A Fluorogenic Probe for the Detection of Sphingosine (2020) (0)
Cyclic Naphthoquinone Imine Based Antagonists of the RIG-I Innate Immune Receptor (2020) (0)
Potent and Selective Inhibitors of Kallikrein-Related Peptidase 6 (2020) (0)
A Versatile Cellular Target Engagement Probe for MPC2 (2020) (0)
Cyclic Disulfides as Selective Thioredoxin Probes (2021) (0)
Tabernanthalog, an Ibogaine Analogue for Treatment of Addiction and Depression (2021) (0)
Activity-Based Profiling of Bile Salt Hydrolases (2019) (0)
Natural Products in Drug Discovery (2020) (0)
Teaching Old Clicks New Tricks (2020) (0)
Structure of GluA2-LBD in complex with MES (2013) (0)
Efficient Synthesis of the Heparin Anticoagulant Idraparinux (2019) (0)
Specific Functionalization of Cysteine and Lysine Using Dinitroimidazoles (2019) (0)
Functionalization and Post-Translational Modification of Cysteines by Tsuji–Trost Reaction (2019) (0)
Fixing a Photosensitizer Unlocks and Localizes Its Lethality (2019) (0)
Potent TAS2R8 Antagonists as Bitterness Blockers (2020) (0)
X-Ene-X (X=F, C1, Br, I, O, S, Se, Te, N, P), Ene-Hal, and Ene-O compounds (2008) (0)
A Route to Complex N-Arylated Alkylamines via Photocatalytic C–H Amination (2019) (0)
Synthesis of Rubioncolin B (2009) (0)
Erythromycin–Fluorophore Conjugates for the Study of Bacterial Resistance Mechanisms in Single-Cells (2021) (0)

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What Schools Are Affiliated With Dirk Trauner?

Dirk Trauner is affiliated with the following schools:

New York University
University of Vienna
University of Pennsylvania
Goethe University Frankfurt
University of California, Berkeley
Ludwig Maximilian University of Munich