Dominique Schols
#124,783
Most Influential Person Now
Researcher
Dominique Schols's AcademicInfluence.com Rankings
Dominique Scholscomputer-science Degrees
Computer Science
#5186
World Rank
#5480
Historical Rank
Artificial Intelligence
#1512
World Rank
#1541
Historical Rank
Database
#2333
World Rank
#2448
Historical Rank

Download Badge
Computer Science
Dominique Schols's Degrees
- PhD Computer Science University of Amsterdam
- Masters Artificial Intelligence University of Amsterdam
- Bachelors Computer Science University of Amsterdam
Similar Degrees You Can Earn
Why Is Dominique Schols Influential?
(Suggest an Edit or Addition)Dominique Schols's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Rapid and automated tetrazolium-based colorimetric assay for the detection of anti-HIV compounds. (1988) (1518)
- CXCR4-activated astrocyte glutamate release via TNFα: amplification by microglia triggers neurotoxicity (2001) (981)
- AMD3100, a small molecule inhibitor of HIV-1 entry via the CXCR4 co-receptor (1998) (765)
- Potent and selective inhibition of HIV-1 replication in vitro by a novel series of TIBO derivatives (1990) (669)
- Inhibition of T-tropic HIV Strains by Selective Antagonization of the Chemokine Receptor CXCR4 (1997) (575)
- Chemokine receptor inhibition by AMD3100 is strictly confined to CXCR4 (2002) (465)
- Safety, Pharmacokinetics, and Antiviral Activity of AMD3100, a Selective CXCR4 Receptor Inhibitor, in HIV-1 Infection (2004) (353)
- Differential antiherpesvirus and antiretrovirus effects of the (S) and (R) enantiomers of acyclic nucleoside phosphonates: potent and selective in vitro and in vivo antiretrovirus activities of (R)-9-(2-phosphonomethoxypropyl)-2,6-diaminopurine (1993) (329)
- Macrophage Tropism of Human Immunodeficiency Virus Type 1 Isolates from Brain and Lymphoid Tissues Predicts Neurotropism Independent of Coreceptor Specificity (2001) (290)
- AMD3100, a Potent and Specific Antagonist of the Stromal Cell-Derived Factor-1 Chemokine Receptor CXCR4, Inhibits Autoimmune Joint Inflammation in IFN-γ Receptor-Deficient Mice1 (2001) (271)
- Amino-terminal Truncation of Chemokines by CD26/Dipeptidyl-peptidase IV (1998) (270)
- Highly specific inhibition of human immunodeficiency virus type 1 by a novel 6-substituted acyclouridine derivative. (1989) (269)
- The Viral Polymerase Inhibitor 7-Deaza-2’-C-Methyladenosine Is a Potent Inhibitor of In Vitro Zika Virus Replication and Delays Disease Progression in a Robust Mouse Infection Model (2016) (251)
- Phosphonylmethoxyethyl purine derivatives, a new class of anti-human immunodeficiency virus agents (1988) (245)
- The mannose-specific plant lectins from Cymbidium hybrid and Epipactis helleborine and the (N-acetylglucosamine)n-specific plant lectin from Urtica dioica are potent and selective inhibitors of human immunodeficiency virus and cytomegalovirus replication in vitro. (1992) (239)
- AMD3100, a CxCR4 antagonist, attenuates allergic lung inflammation and airway hyperreactivity. (2002) (236)
- Potent and selective inhibition of human immunodeficiency virus (HIV)-1 and HIV-2 replication by a class of bicyclams interacting with a viral uncoating event. (1992) (232)
- Alpha-(1-3)- and alpha-(1-6)-D-mannose-specific plant lectins are markedly inhibitory to human immunodeficiency virus and cytomegalovirus infections in vitro (1991) (224)
- Bicyclams, a class of potent anti-HIV agents, are targeted at the HIV coreceptor fusin/CXCR-4. (1997) (223)
- CXCR4 nanobodies (VHH-based single variable domains) potently inhibit chemotaxis and HIV-1 replication and mobilize stem cells (2010) (212)
- Processing by CD26/dipeptidyl‐peptidase IV reduces the chemotactic and anti‐HIV‐1 activity of stromal‐cell‐derived factor‐1α (1998) (207)
- Dextran sulfate and other polyanionic anti-HIV compounds specifically interact with the viral gp120 glycoprotein expressed by T-cells persistently infected with HIV-1. (1990) (198)
- CXCL12-CXCR4 axis in angiogenesis, metastasis and stem cell mobilization. (2010) (196)
- Chloro-1,4-dimethyl-9H-carbazole Derivatives Displaying Anti-HIV Activity (2018) (182)
- CXCR4 as a Functional Coreceptor for Human Immunodeficiency Virus Type 1 Infection of Primary Macrophages (1998) (180)
- Pentosan polysulfate, a sulfated oligosaccharide, is a potent and selective anti-HIV agent in vitro. (1988) (179)
- Resistance Mutations in Human Immunodeficiency Virus Type 1 Integrase Selected with Elvitegravir Confer Reduced Susceptibility to a Wide Range of Integrase Inhibitors (2008) (179)
- STAT2 signaling restricts viral dissemination but drives severe pneumonia in SARS-CoV-2 infected hamsters (2020) (173)
- Sulfated polymers inhibit the interaction of human cytomegalovirus with cell surface heparan sulfate. (1992) (167)
- Potent and highly selective human immunodeficiency virus type 1 (HIV-1) inhibition by a series of alpha-anilinophenylacetamide derivatives targeted at HIV-1 reverse transcriptase. (1993) (162)
- HIV-1 gp120 and chemokines activate ion channels in primary macrophages through CCR5 and CXCR4 stimulation. (2000) (161)
- HIV-1 gp120 and chemokine activation of Pyk2 and mitogen-activated protein kinases in primary macrophages mediated by calcium-dependent, pertussis toxin-insensitive chemokine receptor signaling. (2001) (161)
- CD26/dipeptidyl-peptidase IV down-regulates the eosinophil chemotactic potency, but not the anti-HIV activity of human eotaxin by affecting its interaction with CC chemokine receptor 3. (1999) (160)
- Polyanionic (i.e., polysulfonate) dendrimers can inhibit the replication of human immunodeficiency virus by interfering with both virus adsorption and later steps (reverse transcriptase/integrase) in the virus replicative cycle. (2000) (157)
- Truncation of Macrophage-derived Chemokine by CD26/ Dipeptidyl-Peptidase IV beyond Its Predicted Cleavage Site Affects Chemotactic Activity and CC Chemokine Receptor 4 Interaction* (1999) (155)
- Antiviral agents active against human herpesviruses HHV‐6, HHV‐7 and HHV‐8 (2001) (151)
- Determinants for Sensitivity of Human Immunodeficiency Virus Coreceptor CXCR4 to the Bicyclam AMD3100 (1998) (151)
- In Vivo Evolution of Human Immunodeficiency Virus Type 1 toward Increased Pathogenicity through CXCR4-Mediated Killing of Uninfected CD4 T Cells (2003) (147)
- Mannose-Specific Plant Lectins from the Amaryllidaceae Family Qualify as Efficient Microbicides for Prevention of Human Immunodeficiency Virus Infection (2004) (147)
- Evaluation of a panel of 28 biomarkers for the non-invasive diagnosis of endometriosis. (2012) (144)
- 2',5'-Bis-O-(tert-butyldimethylsilyl)-3'-spiro-5''-(4''-amino-1'',2''- oxathiole-2'',2'-dioxide)pyrimidine (TSAO) nucleoside analogues: highlyselective inhibitors of human immunodeficiency virus type 1 that are targeted at the viral reverse transcriptase. (1992) (143)
- Role of CXCR4 in Cell-Cell Fusion and Infection of Monocyte-Derived Macrophages by Primary Human Immunodeficiency Virus Type 1 (HIV-1) Strains: Two Distinct Mechanisms of HIV-1 Dual Tropism (1999) (130)
- A single-dose live-attenuated YF17D-vectored SARS-CoV-2 vaccine candidate (2020) (120)
- Indolylarylsulfones as HIV-1 non-nucleoside reverse transcriptase inhibitors: new cyclic substituents at indole-2-carboxamide. (2011) (120)
- Anti-SCID mouse reactivity shapes the human CD4+ T cell repertoire in hu-PBL-SCID chimeras (1994) (119)
- AMD3465, a monomacrocyclic CXCR4 antagonist and potent HIV entry inhibitor. (2005) (116)
- Human immunodeficiency virus glycoprotein gp120 as the primary target for the antiviral action of AR177 (Zintevir). (1998) (116)
- Enhanced autoimmune arthritis in IFN-gamma receptor-deficient mice is conditioned by mycobacteria in Freund's adjuvant and by increased expansion of Mac-1+ myeloid cells. (1999) (115)
- Carbohydrate-binding Agents Cause Deletions of Highly Conserved Glycosylation Sites in HIV GP120 (2005) (114)
- Shift of Clinical Human Immunodeficiency Virus Type 1 Isolates from X4 to R5 and Prevention of Emergence of the Syncytium-Inducing Phenotype by Blockade of CXCR4 (1999) (114)
- The Lantibiotic Peptide Labyrinthopeptin A1 Demonstrates Broad Anti-HIV and Anti-HSV Activity with Potential for Microbicidal Applications (2013) (114)
- T-Cell-Line-Tropic Human Immunodeficiency Virus Type 1 That Is Made Resistant to Stromal Cell-Derived Factor 1α Contains Mutations in the Envelope gp120 but Does Not Show a Switch in Coreceptor Use (1998) (113)
- Molecular Mechanism of Action of Monocyclam Versus Bicyclam Non-peptide Antagonists in the CXCR4 Chemokine Receptor* (2007) (111)
- Viral entry as the primary target for the anti-HIV activity of chicoric acid and its tetra-acetyl esters. (2000) (109)
- Novel sulfated polymers as highly potent and selective inhibitors of human immunodeficiency virus replication and giant cell formation (1990) (109)
- Specific interaction of aurintricarboxylic acid with the human immunodeficiency virus/CD4 cell receptor. (1989) (107)
- Investigation of Griffithsin's Interactions with Human Cells Confirms Its Outstanding Safety and Efficacy Profile as a Microbicide Candidate (2011) (107)
- Preferential coreceptor utilization and cytopathicity by dual-tropic HIV-1 in human lymphoid tissue ex vivo. (1999) (107)
- Diverging binding capacities of natural LD78β isoforms of macrophage inflammatory protein‐1α to the CC chemokine receptors 1, 3 and 5 affect their anti‐HIV‐1 activity and chemotactic potencies for neutrophils and eosinophils (2001) (107)
- Microvirin, a Novel α(1,2)-Mannose-specific Lectin Isolated from Microcystis aeruginosa, Has Anti-HIV-1 Activity Comparable with That of Cyanovirin-N but a Much Higher Safety Profile* (2010) (106)
- Mutation of Asp(171) and Asp(262) of the chemokine receptor CXCR4 impairs its coreceptor function for human immunodeficiency virus-1 entry and abrogates the antagonistic activity of AMD3100. (2001) (105)
- Enhanced anti-HIV-1 activity and altered chemotactic potency of NH2-terminally processed macrophage-derived chemokine (MDC) imply an additional MDC receptor. (1998) (104)
- Pro-inflammatory properties of stromal cell-derived factor-1 (CXCL12) in collagen-induced arthritis (2005) (104)
- The LD78beta isoform of MIP-1alpha is the most potent CCR5 agonist and HIV-1-inhibiting chemokine. (1999) (103)
- Selective inhibition of human cytomegalovirus DNA synthesis by (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine [(S)-HPMPC] and 9-(1,3-dihydroxy-2-propoxymethyl)guanine (DHPG). (1990) (102)
- The role of CD26/DPP IV in chemokine processing. (1999) (101)
- Human immunodeficiency virus type 1 gp120 induces anergy in human peripheral blood lymphocytes by inducing interleukin-10 production (1996) (100)
- Mutational Pathways, Resistance Profile, and Side Effects of Cyanovirin Relative to Human Immunodeficiency Virus Type 1 Strains with N-Glycan Deletions in Their gp120 Envelopes (2006) (99)
- Profile of Resistance of Human Immunodeficiency Virus to Mannose-Specific Plant Lectins (2004) (97)
- Activity of different bicyclam derivatives against human immunodeficiency virus depends on their interaction with the CXCR4 chemokine receptor. (1999) (97)
- Citrullination of CXCL12 Differentially Reduces CXCR4 and CXCR7 Binding with Loss of Inflammatory and Anti-HIV-1 Activity via CXCR41 (2009) (97)
- Pradimicin A, a Carbohydrate-Binding Nonpeptidic Lead Compound for Treatment of Infections with Viruses with Highly Glycosylated Envelopes, Such as Human Immunodeficiency Virus (2006) (93)
- Induction of apoptosis by cidofovir in human papillomavirus (HPV)-positive cells. (2001) (93)
- Discovery of novel small molecule orally bioavailable C-X-C chemokine receptor 4 antagonists that are potent inhibitors of T-tropic (X4) HIV-1 replication. (2010) (92)
- Flow cytometric method to demonstrate whether anti-HIV-1 agents inhibit virion binding to T4+ cells. (1989) (89)
- Synthesis and structure-activity relationships of phenylenebis(methylene)-linked bis-azamacrocycles that inhibit HIV-1 and HIV-2 replication by antagonism of the chemokine receptor CXCR4. (1999) (87)
- Lymphoid and myeloid differentiation of fetal liver CD34+lineage- cells in human thymic organ culture (1994) (86)
- Interleukin-8 and Growth-Regulated Oncogene Alpha Mediate Angiogenesis in Kaposi's Sarcoma (2002) (85)
- Development of resistance of human immunodeficiency virus type 1 to dextran sulfate associated with the emergence of specific mutations in the envelope gp120 glycoprotein. (1997) (84)
- Mechanism of anti-human immunodeficiency virus action of polyoxometalates, a class of broad-spectrum antiviral agents. (1992) (84)
- A second target for the peptoid Tat/transactivation response element inhibitor CGP64222: inhibition of human immunodeficiency virus replication by blocking CXC-chemokine receptor 4-mediated virus entry. (2000) (82)
- Preparation and anti-HIV activities of aurintricarboxylic acid fractions and analogues: direct correlation of antiviral potency with molecular weight. (1991) (80)
- Pyridine N-oxide derivatives: unusual anti-HIV compounds with multiple mechanisms of antiviral action. (2005) (80)
- Inhibition of Human Immunodeficiency Virus Replication by a Dual CCR5/CXCR4 Antagonist (2004) (80)
- Carbohydrate-Binding Agents Efficiently Prevent Dendritic Cell-Specific Intercellular Adhesion Molecule-3-Grabbing Nonintegrin (DC-SIGN)-Directed HIV-1 Transmission to T Lymphocytes (2007) (79)
- Sulphated Polymers are Potent and Selective Inhibitors of Various Enveloped Viruses, Including Herpes Simplex Virus, Cytomegalovirus, Vesicular Stomatitis Virus, Respiratory Syncytial Virus, and Toga-, Arena- and Retroviruses (1990) (78)
- Engineering a Therapeutic Lectin by Uncoupling Mitogenicity from Antiviral Activity (2015) (78)
- Viral Entry through CXCR4 Is a Pathogenic Factor and Therapeutic Target in Human Immunodeficiency Virus Type 1 Disease (2000) (78)
- CADA, a novel CD4-targeted HIV inhibitor, is synergistic with various anti-HIV drugs in vitro (2004) (78)
- Safety concerns for the potential use of cyanovirin-N as a microbicidal anti-HIV agent. (2008) (78)
- Bicyclams, Selective Antagonists of the Human Chemokine Receptor CXCR4, Potently Inhibit Feline Immunodeficiency Virus Replication (1999) (77)
- A Derivate of the Antibiotic Doxorubicin Is a Selective Inhibitor of Dengue and Yellow Fever Virus Replication In Vitro (2010) (76)
- Apoptosis of Bystander T Cells Induced by Human Immunodeficiency Virus Type 1 with Increased Envelope/Receptor Affinity and Coreceptor Binding Site Exposure (2004) (74)
- Nuclear localization of human immunodeficiency virus type 1 integrase expressed as a fusion protein with green fluorescent protein. (1999) (74)
- CD26-processed RANTES(3-68), but not intact RANTES, has potent anti-HIV-1 activity. (1998) (73)
- Algal Lectins as Potential HIV Microbicide Candidates (2012) (73)
- CADA inhibits human immunodeficiency virus and human herpesvirus 7 replication by down-modulation of the cellular CD4 receptor. (2002) (71)
- Entry of hepatitis C virus and human immunodeficiency virus is selectively inhibited by carbohydrate-binding agents but not by polyanions. (2007) (70)
- Evaluation of SDF‐1/CXCR4‐induced Ca2+ signaling by fluorometric imaging plate reader (FLIPR) and flow cytometry (2003) (68)
- Novel sulfated polysaccharides: dissociation of anti-human immunodeficiency virus activity from antithrombin activity. (1990) (68)
- Marked Depletion of Glycosylation Sites in HIV-1 gp120 under Selection Pressure by the Mannose-Specific Plant Lectins of Hippeastrum Hybrid and Galanthus nivalis (2005) (67)
- Primary mutations selected in vitro with raltegravir confer large fold changes in susceptibility to first-generation integrase inhibitors, but minor fold changes to inhibitors with second-generation resistance profiles. (2010) (66)
- Potent in vitro anti-human immunodeficiency virus-1 activity of modified human serum albumins. (1991) (65)
- Presence of class II histocompatibility DR proteins on the envelope of human immunodeficiency virus demonstrated by FACS analysis. (1992) (64)
- Identification of a Subset of Human Immunodeficiency Virus Type 1 (HIV-1), HIV-2, and Simian Immunodeficiency Virus Strains Able To Exploit an Alternative Coreceptor on Untransformed Human Brain and Lymphoid Cells (2003) (63)
- Dengue Virus Entry as Target for Antiviral Therapy (2012) (62)
- Lectin-Like Molecules of Lactobacillus rhamnosus GG Inhibit Pathogenic Escherichia coli and Salmonella Biofilm Formation (2016) (62)
- Sulfonic acid polymers as a new class of human immunodeficiency virus inhibitors. (1992) (61)
- HIV co-receptors as targets for antiviral therapy. (2004) (61)
- A Human Immunodeficiency Virus Type 1 Isolate from an Infected Person Homozygous for CCR5Δ32 Exhibits Dual Tropism by Infecting Macrophages and MT2 Cells via CXCR4 (2002) (60)
- The Anti-HIV potency of cyclotriazadisulfonamide analogs is directly correlated with their ability to down-modulate the CD4 receptor. (2003) (60)
- ACYCLIC/CARBOCYCLIC GUANOSINE ANALOGUES AS ANTI-HERPESVIRUS AGENTS (2001) (60)
- New tetrahydroimidazo[4,5,1-jk][1,4]-benzodiazepin-2(1H)-one and -thione derivatives are potent inhibitors of human immunodeficiency virus type 1 replication and are synergistic with 2',3'-dideoxynucleoside analogs (1994) (59)
- Viral Interactions in Human Lymphoid Tissue: Human Herpesvirus 7 Suppresses the Replication of CCR5-Tropic Human Immunodeficiency Virus Type 1 via CD4 Modulation (2006) (58)
- Broad Antiviral Activity of Carbohydrate-Binding Agents against the Four Serotypes of Dengue Virus in Monocyte-Derived Dendritic Cells (2011) (58)
- Potent anti-HIV (type 1 and type 2) activity of polyoxometalates: structure-activity relationship and mechanism of action. (2000) (58)
- Novel, negatively charged, human serum albumins display potent and selective in vitro anti-human immunodeficiency virus type 1 activity. (1993) (58)
- Actinohivin, a Broadly Neutralizing Prokaryotic Lectin, Inhibits HIV-1 Infection by Specifically Targeting High-Mannose-Type Glycans on the gp120 Envelope (2010) (56)
- Antiviral activity of carbohydrate-binding agents and the role of DC-SIGN in dengue virus infection. (2009) (56)
- Inhibition of HIV infection by CXCR4 and CCR5 chemokine receptor antagonists. (2001) (55)
- Sugar-Binding Proteins Potently Inhibit Dendritic Cell Human Immunodeficiency Virus Type 1 (HIV-1) Infection and Dendritic-Cell-Directed HIV-1 Transfer (2005) (55)
- Differential Cytokine, Chemokine and Growth Factor Expression in Phenotypes of Chronic Lung Allograft Dysfunction (2015) (54)
- The LD78β Isoform of MIP-1α Is the Most Potent CC-Chemokine in Inhibiting CCR5-Dependent Human Immunodeficiency Virus Type 1 Replication in Human Macrophages (2001) (54)
- Activity of acyclic nucleoside phosphonate analogues against human immunodeficiency virus in monocyte/macrophages and peripheral blood lymphocytes. (1991) (53)
- Highly favorable antiviral activity and resistance profile of the novel thiocarboxanilide pentenyloxy ether derivatives UC-781 and UC-82 as inhibitors of human immunodeficiency virus type 1 replication. (1996) (53)
- Antiviral Activity of low-MW Dextran Sulphate (Derived from dextran MW 1000) Compared to Dextran Sulphate Samples of Higher MW (1991) (52)
- Synthesis and anti-HIV activities of low molecular weight aurintricarboxylic acid fragments and related compounds. (1991) (51)
- Synergistic activity profile of griffithsin in combination with tenofovir, maraviroc and enfuvirtide against HIV-1 clade C. (2011) (51)
- Mechanisms underlying activity of antiretroviral drugs in HIV‐1‐infected macrophages: new therapeutic strategies (2006) (51)
- The Low-Cost Compound Lignosulfonic Acid (LA) Exhibits Broad-Spectrum Anti-HIV and Anti-HSV Activity and Has Potential for Microbicidal Applications (2015) (49)
- In Vivo Evolution of X4 Human Immunodeficiency Virus Type 1 Variants in the Natural Course of Infection Coincides with Decreasing Sensitivity to CXCR4 Antagonists (2004) (48)
- Lipophilic prodrugs of nucleoside triphosphates as biochemical probes and potential antivirals (2015) (48)
- Selective activity of various antiviral compounds against HHV-7 infection. (1999) (48)
- HIV chemokine receptor inhibitors as novel anti-HIV drugs. (2005) (48)
- New nitrogen containing substituents at the indole-2-carboxamide yield high potent and broad spectrum indolylarylsulfone HIV-1 non-nucleoside reverse transcriptase inhibitors. (2012) (48)
- Synthesis and structure-activity relationships of azamacrocyclic C-X-C chemokine receptor 4 antagonists: analogues containing a single azamacrocyclic ring are potent inhibitors of T-cell tropic (X4) HIV-1 replication. (2010) (48)
- Polyanion inhibitors of HIV and other viruses. 7. Polyanionic compounds and polyzwitterionic compounds derived from cyclodextrins as inhibitors of HIV transmission. (1998) (47)
- Establishment of a novel CCR5 and CXCR4 expressing CD4+ cell line which is highly sensitive to HIV and suitable for high-throughput evaluation of CCR5 and CXCR4 antagonists (2004) (47)
- The simian immunodeficiency virus mnd(GB-1) strain uses CXCR4, not CCR5, as coreceptor for entry in human cells. (1998) (47)
- Impact of Cytokines on Replication in the Thymus of Primary Human Immunodeficiency Virus Type 1 Isolates from Infants (2002) (46)
- Differential antiviral activity of derivatized dextrans. (1995) (46)
- Therapeutic strategies towards HIV-1 infection in macrophages. (2006) (46)
- STAT2 signaling as double-edged sword restricting viral dissemination but driving severe pneumonia in SARS-CoV-2 infected hamsters (2020) (45)
- Fuchsin acid selectively inhibits human immunodeficiency virus (HIV) replication in vitro. (1988) (45)
- Combinations of griffithsin with other carbohydrate-binding agents demonstrate superior activity against HIV Type 1, HIV Type 2, and selected carbohydrate-binding agent-resistant HIV Type 1 strains. (2012) (44)
- Steroids can reduce warm ischemic reperfusion injury in a porcine donation after circulatory death model with ex vivo lung perfusion evaluation (2016) (44)
- Discovery of antitumor anthra[2,3-b]furan-3-carboxamides: Optimization of synthesis and evaluation of antitumor properties. (2016) (44)
- CXCR4 and CCR5 ligands cooperate in monocyte and lymphocyte migration and in inhibition of dual‐tropic (R5/X4) HIV‐1 infection (2011) (44)
- Lectin-Glycan Interaction Network-Based Identification of Host Receptors of Microbial Pathogenic Adhesins (2016) (44)
- IL-4 induces human B cell maturation and IgE synthesis in SCID-hu mice. Inhibition of ongoing IgE production by in vivo treatment with an IL-4/IL-13 receptor antagonist. (1995) (44)
- RANTES and MCP-3 inhibit the replication of T-cell-tropic human immunodeficiency virus type 1 strains (SF-2, MN, and HE) (1997) (43)
- Syncytium formation and destruction of bystander CD4+ cells cocultured with T cells persistently infected with human immunodeficiency virus as demonstrated by flow cytometry. (1989) (43)
- Resistance of HIV-1 to the broadly HIV-1-neutralizing, anti-carbohydrate antibody 2G12. (2007) (43)
- DC-SIGN Increases the Affinity of HIV-1 Envelope Glycoprotein Interaction with CD4 (2011) (43)
- Pradimicin S, a Highly Soluble Nonpeptidic Small-Size Carbohydrate-Binding Antibiotic, Is an Anti-HIV Drug Lead for both Microbicidal and Systemic Use (2010) (42)
- Immunoregulatory effects of multipotent adult progenitor cells in a porcine ex vivo lung perfusion model (2017) (42)
- The candidate sulfonated microbicide, PRO 2000, has potential multiple mechanisms of action against HIV-1. (2009) (41)
- SRR-SB3, a disulfide-containing macrolide that inhibits a late stage of the replicative cycle of human immunodeficiency virus (1997) (41)
- Highly stable hexitol based XNA aptamers targeting the vascular endothelial growth factor (2019) (41)
- 2-Chloro-3-pyridin-3-yl-5,6,7,8-tetrahydroindolizine-1-carboxamide (CMV423), a new lead compound for the treatment of human cytomegalovirus infections. (2002) (40)
- Different contributions of chemokine N‐terminal features attest to a different ligand binding mode and a bias towards activation of ACKR3/CXCR7 compared with CXCR4 and CXCR3 (2017) (40)
- Different Evolution of Genotypic Resistance Profiles to Emtricitabine Versus Lamivudine in Tenofovir-Containing Regimens (2010) (40)
- Inhibitory activity of S-adenosylhomocysteine hydrolase inhibitors against human cytomegalovirus replication. (1993) (40)
- HIV co-receptor inhibitors as novel class of anti-HIV drugs. (2006) (40)
- Signal Peptide-Binding Drug as a Selective Inhibitor of Co-Translational Protein Translocation (2014) (40)
- Total synthesis of the antiviral peptide antibiotic feglymycin. (2009) (39)
- Membrane-permeable Triphosphate Prodrugs of Nucleoside Analogues. (2016) (39)
- Quantitative evaluation of HIV-1 coreceptor use in the GHOST3 cell assay. (2001) (39)
- Selective inhibitory activity of polyhydroxycarboxylates derived from phenolic compounds against human immunodeficiency virus replication. (1991) (39)
- Nanobody‐Fc constructs targeting chemokine receptor CXCR4 potently inhibit signaling and CXCR4‐mediated HIV‐entry and induce antibody effector functions (2018) (38)
- HIV-1 X4 activities of polycationic "viologen" based dendrimers by interaction with the chemokine receptor CXCR4: study of structure-activity relationship. (2012) (38)
- Carbohydrate-binding agents (CBAs) inhibit HIV-1 infection in human primary monocyte-derived macrophages (MDMs) and efficiently prevent MDM-directed viral capture and subsequent transmission to CD4+ T lymphocytes. (2008) (38)
- Fluorescent CXCL12AF647 as a novel probe for nonradioactive CXCL12/CXCR4 cellular interaction studies (2004) (38)
- Synthesis and structure-activity relationship studies of CD4 down-modulating cyclotriazadisulfonamide (CADA) analogues. (2006) (38)
- Broad anti-HIV activity of the Oscillatoria agardhii agglutinin homologue lectin family. (2014) (38)
- Resistance to raltegravir highlights integrase mutations at codon 148 in conferring cross-resistance to a second-generation HIV-1 integrase inhibitor. (2011) (37)
- The molecular pharmacology of AMD11070: an orally bioavailable CXCR4 HIV entry inhibitor. (2012) (37)
- Anti-human immunodeficiency virus effects of cationic metalloporphyrin-ellipticine complexes. (1992) (36)
- Coreceptor Phenotype of Natural Human Immunodeficiency Virus with Nef Deleted Evolves In Vivo, Leading to Increased Virulence (2002) (36)
- Cell type-specific anti-human immunodeficiency virus type 1 activity of the transactivation inhibitor Ro5-3335 (1992) (36)
- Thioredoxin-1 and protein disulfide isomerase catalyze the reduction of similar disulfides in HIV gp120. (2012) (36)
- In vivo cytokine expression in the thymus. CD3high human thymocytes are activated and already functionally differentiated in helper and cytotoxic cells. (1994) (35)
- A yellow fever–Zika chimeric virus vaccine candidate protects against Zika infection and congenital malformations in mice (2018) (35)
- Mutations at the CXCR4 interaction sites for AMD3100 influence anti‐CXCR4 antibody binding and HIV‐1 entry (2003) (35)
- Sulphated Cyclodextrins are Potent anti-HIV Agents Acting Synergistically with 2′,3′-dideoxynucleoside Analogues (1991) (35)
- Comparison of cell-based assays for the identification and evaluation of competitive CXCR4 inhibitors (2017) (35)
- Indolylarylsulfones carrying a heterocyclic tail as very potent and broad spectrum HIV-1 non-nucleoside reverse transcriptase inhibitors. (2014) (35)
- Nucleoside Diphosphate Prodrugs: Nonsymmetric DiPPro-Nucleotides. (2015) (35)
- Sulfated Escherichia coli K5 Polysaccharide Derivatives Inhibit Dengue Virus Infection of Human Microvascular Endothelial Cells by Interacting with the Viral Envelope Protein E Domain III (2013) (34)
- Tetrazolium-based plaque assay for HIV-1 and HIV-2, and its use in the evaluation of antiviral compounds. (1989) (34)
- Humoral immunity in phenotypes of chronic lung allograft dysfunction: A broncho-alveolar lavage fluid analysis. (2016) (34)
- Vascular endothelial growth factor pathway in endometriosis: genetic variants and plasma biomarkers. (2016) (33)
- Preparation and anti-HIV activity of O-acylated heparin and dermatan sulfate derivatives with low anticoagulant effect. (1993) (33)
- Differential in vitro inhibitory activity against HIV-1 of alpha-(1-3)- and alpha-(1-6)-D-mannose specific plant lectins : Implication for microbicide development (2007) (32)
- Chloroquine accumulates in breast-milk cells: potential impact in the prophylaxis of postnatal mother-to-child transmission of HIV-1. (2001) (32)
- The lectin-like protein 1 in Lactobacillus rhamnosus GR-1 mediates tissue-specific adherence to vaginal epithelium and inhibits urogenital pathogens (2016) (32)
- Azithromycin and the Treatment of Lymphocytic Airway Inflammation After Lung Transplantation (2014) (32)
- Reduced Fitness of HIV-1 Resistant to Cxcr4 Antagonists (2003) (32)
- Targeting HIV entry through interaction with envelope glycoprotein 120 (gp120): synthesis and antiviral evaluation of 1,3,5-triazines with aromatic amino acids. (2011) (32)
- CXCR4‐targeting nanobodies differentially inhibit CXCR4 function and HIV entry (2018) (32)
- Crucial role of the N-glycans on the viral E-envelope glycoprotein in DC-SIGN-mediated dengue virus infection. (2012) (31)
- CXCR4 chemokine receptor antagonists: nickel(II) complexes of configurationally restricted macrocycles. (2012) (31)
- Human Ig production and isotype switching in severe combined immunodeficient-human mice. (1993) (30)
- New AMD3100 derivatives for CXCR4 chemokine receptor targeted molecular imaging studies: synthesis, anti-HIV-1 evaluation and binding affinities. (2015) (30)
- 5-Halogeno-3'-fluoro-2',3'-dideoxyuridines as inhibitors of human immunodeficiency virus (HIV): potent and selective anti-HIV activity of 3'-fluoro-2',3'-dideoxy-5-chlorouridine. (1989) (30)
- HIV-1 entry inhibition by small-molecule CCR5 antagonists: a combined molecular modeling and mutant study using a high-throughput assay. (2011) (30)
- A new class of dual-targeted antivirals: monophosphorylated acyclovir prodrug derivatives suppress both human immunodeficiency virus type 1 and herpes simplex virus type 2. (2010) (30)
- Anti-HIV activity profile of AMD070, an orally bioavailable CXCR4 antagonist (2003) (30)
- Anti-HIV Activities of Anionic Metalloporphyrins and Related Compounds (1997) (30)
- Design, synthesis, antiviral and cytostatic activity of ω-(1H-1,2,3-triazol-1-yl)(polyhydroxy)alkylphosphonates as acyclic nucleotide analogues (2014) (30)
- Detection of immediate early, early and late antigens of human cytomegalovirus by flow cytometry. (1989) (29)
- Antiviral activity of anti-cytomegalovirus agents (HPMPC, HPMPA) assessed by a flow cytometric method and DNA hybridization technique. (1991) (29)
- 2-(4-Chlorobenzyl)-6-arylimidazo[2,1-b][1,3,4]thiadiazoles: synthesis, cytotoxic activity and mechanism of action. (2014) (29)
- Anti-HIV agents targeting the interaction of gp120 with the cellular CD4 receptor (2005) (29)
- Study of the Chemoselectivity of Multicomponent Heterocyclizations Involving 3-Amino-1,2,4-triazole and Pyruvic Acids as Key Reagents, and Biological Activity of the Reaction Products (2015) (28)
- Specific CD4 down‐modulating compounds with potent anti‐HIV activity (2003) (28)
- High mannose-specific lectin Msl mediates key interactions of the vaginal Lactobacillus plantarum isolate CMPG5300 (2016) (28)
- Novel urea and bis-urea primaquine derivatives with hydroxyphenyl or halogenphenyl substituents: Synthesis and biological evaluation. (2016) (28)
- The role of N-glycosylation sites on the CXCR4 receptor for CXCL-12 binding and signaling and X4 HIV-1 viral infectivity. (2007) (27)
- A highly reliable, sensitive, flow cytometric/fluorometric assay for the evaluation of the anti-HIV activity of antiviral compounds in MT-4 cells. (1988) (27)
- Differential Activity of Polyanionic Compounds and Castanospermine against HIV Replication and HIV-Induced Syncytium Formation Depending on Virus Strain and Cell Type (1992) (27)
- Long-Lasting Enfuvirtide Carrier Pentasaccharide Conjugates with Potent Anti-Human Immunodeficiency Virus Type 1 Activity (2009) (27)
- Imbalance in production of cytokines by bone marrow stromal cells following cytomegalovirus infection. (1996) (27)
- Pronounced in vitro and in vivo antiretroviral activity of 5-substituted 2,4-diamino-6-[2-(phosphonomethoxy)ethoxy] pyrimidines. (2006) (27)
- Novel semicarbazides and ureas of primaquine with bulky aryl or hydroxyalkyl substituents: synthesis, cytostatic and antioxidative activity. (2014) (27)
- A single-dose live-attenuated YF17D-vectored SARS-CoV-2 vaccine candidate (2020) (27)
- Synthesis and SAR of novel CXCR4 antagonists that are potent inhibitors of T tropic (X4) HIV-1 replication. (2011) (26)
- Differences in the mannose oligomer specificities of the closely related lectins from Galanthus nivalis and Zea mays strongly determine their eventual anti-HIV activity (2011) (26)
- New antitumor anthra[2,3-b]furan-3-carboxamides: Synthesis and structure-activity relationship. (2018) (24)
- Design, Synthesis, and Antiviral Activity of Novel Ribonucleosides of 1,2,3‐Triazolylbenzyl‐aminophosphonates (2015) (24)
- NICTABA and UDA, two GlcNAc-binding lectins with unique antiviral activity profiles (2015) (24)
- Inhibitors of HIV infection via the cellular CD4 receptor. (2006) (24)
- Design of novel CXCR4 antagonists that are potent inhibitors of T-tropic (X4) HIV-1 replication. (2011) (23)
- 9-(2-Phosphonylmethoxyethyl)adenine induces tumor cell differentiation or cell death by blocking cell cycle progression through the S phase. (1999) (23)
- Comparative activity of selected antiviral compounds against clinical isolates of human cytomegalovirus (1991) (23)
- 1-β-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide (ribavirin) and 5-ethynyl-1-β-D-ribofuranosylimidazole-4-carboxamide (EICAR) markedly potentiate the inhibitory effect of 2′,3′-dideoxyinosine on human immunodeficiency virus in peripheral blood lymphocytes (1991) (23)
- Atypical response to bacterial coinfection and persistent neutrophilic bronchoalveolar inflammation distinguish critical COVID-19 from influenza (2021) (23)
- Polysulfonates Derived from Metal Thiolate Complexes as Inhibitors of HIV-1 and Various other Enveloped Viruses In Vitro (2002) (22)
- Design, Synthesis and Biological Evaluation of Novel Primaquine-Cinnamic Acid Conjugates of the Amide and Acylsemicarbazide Type (2016) (22)
- Design, antiviral and cytostatic properties of isoxazolidine-containing amonafide analogues (2015) (22)
- Coreceptor choice and T cell depletion by R5, X4, and R5X4 HIV-1 variants in CCR5-deficient (CCR5delta32) and normal human lymphoid tissue. (2001) (22)
- Cyclotriazadisulfonamides: promising new CD4-targeted anti-HIV drugs. (2005) (21)
- Flow cytometric method for the detection of gpI antigens of varicella zoster virus and evaluation of anti-VZV agents. (1992) (21)
- Unique cytokine production profile of anergic human T cells in SCID-hu mice after staphylococcal enterotoxin B administration. (1995) (20)
- CADA, a potential anti-HIV microbicide that specifically targets the cellular CD4 receptor. (2008) (20)
- Synthesis of different types of alkoxy fullerene derivatives from chlorofullerene C60Cl6. (2017) (20)
- Prone Positioning During Ex Vivo Lung Perfusion Influences Regional Edema Accumulation. (2019) (20)
- Synthesis, anti-varicella-zoster virus and anti-cytomegalovirus activity of quinazoline-2,4-diones containing isoxazolidine and phosphonate substructures (2016) (20)
- Feglymycin, a unique natural bacterial antibiotic peptide, inhibits HIV entry by targeting the viral envelope protein gp120. (2012) (20)
- Coreceptor ligand inhibition of fetal brain cell infection by HIV type 1. (1999) (19)
- Synergistic in vitro anti-HIV type 1 activity of tenofovir with carbohydrate-binding agents (CBAs). (2011) (19)
- Labyrinthopeptins Exert Broad-Spectrum Antiviral Activity through Lipid-Binding-Mediated Virolysis (2019) (19)
- Agonist-Induced Internalization of CC Chemokine Receptor 5 as a Mechanism to Inhibit HIV Replication (2011) (18)
- Immunocytochemical demonstration of proopiomelanocortin- and other opioid-related substances and a CRF-like peptide in the gut of the american cockroach, Periplaneta americana L. (2004) (18)
- Signaling properties of the human chemokine receptors CXCR4 and CXCR7 by cellular electric impedance measurements (2017) (18)
- Coreceptor usage of sequential isolates from cynomolgus monkeys experimentally Infected with simian immunodeficiency virus (SIVsm). (2001) (18)
- Broad spectrum anti-coronavirus activity of a series of anti-malaria quinoline analogues (2021) (18)
- CD4 down-modulating compounds with potent anti-HIV activity. (2004) (18)
- Obligatory involvement of CD26/dipeptidyl peptidase IV in the activation of the antiretroviral tripeptide glycylprolylglycinamide (GPG-NH(2)). (2004) (17)
- Tri-armed ligands of G-quadruplex on heteroarene-fused anthraquinone scaffolds: Design, synthesis and pre-screening of biological properties. (2018) (17)
- Expanding the Antiviral Spectrum of 3-Fluoro-2-(phosphonomethoxy)propyl Acyclic Nucleoside Phosphonates: Diamyl Aspartate Amidate Prodrugs. (2017) (17)
- Flow cytometric method to monitor the destruction of CD4+ cells following their fusion with HIV-infected cells. (1990) (17)
- Discovery of HIV entry inhibitors via a hybrid CXCR4 and CCR5 receptor pharmacophore‐based virtual screening approach (2020) (17)
- Inhibitory Effects of Polycations on the Replication of Enveloped Viruses (HIV, HSV, CMV, RSV, Influenza A Virus and Togaviruses) in vitro (1991) (17)
- Structural investigation and anti-HIV activities of high molecular weight ATA polymers (1992) (17)
- Antitumor and antiviral activities of 4-substituted 1,2,3-triazolyl-2,3-dibenzyl-L-ascorbic acid derivatives (2019) (17)
- Modified Cyclodextrin Sulphates(mCDS11) have Potent Inhibitory Activity against HIV and High Oral Bioavailability (1994) (16)
- Sensitive, reproducible and convenient fluorometric assay for the in vitro evaluation of anti-cytomegalovirus agents. (1991) (16)
- New Polyacetal Polysulphate Active against Human Immunodeficiency Virus and other Enveloped Viruses (1992) (16)
- Polyanion inhibitors of human immunodeficiency virus and other viruses. Part 2. Polymerized anionic surfactants derived from amino acids and dipeptides. (1996) (16)
- Tuning Side Arm Electronics in Unsymmetrical Cyclotriazadisulfonamide (CADA) Endoplasmic Reticulum (ER) Translocation Inhibitors to Improve their Human Cluster of Differentiation 4 (CD4) Receptor Down-Modulating Potencies. (2016) (16)
- A chimeric yellow fever-Zika virus vaccine candidate fully protects against yellow fever virus infection in mice (2020) (16)
- Engineering Lactobacillus rhamnosus GG and GR-1 to express HIV-inhibiting griffithsin. (2018) (16)
- Anti-HIV-1 activity of antiviral compounds, as quantitated by a focal immunoassay in CD4+ HeLa cells and a plaque assay in MT-4 cells. (1990) (16)
- Novel In Vivo Model for the Study of Human Immunodeficiency Virus Type 1 Transcription Inhibitors: Evaluation of New 6-Desfluoroquinolone Derivatives (2007) (16)
- Alkylated benzimidazoles: Design, synthesis, docking, DFT analysis, ADMET property, molecular dynamics and activity against HIV and YFV (2020) (16)
- Unsymmetrical cyclotriazadisulfonamide (CADA) compounds as human CD4 receptor down-modulating agents. (2011) (16)
- Prospective CCR5 small molecule antagonist compound design using a combined mutagenesis/modeling approach. (2011) (16)
- A Multi-targeted Drug Candidate with Dual Anti-HIV and Anti-HSV Activity (2013) (15)
- A Proteomic Survey Indicates Sortilin as a Secondary Substrate of the ER Translocation Inhibitor Cyclotriazadisulfonamide (CADA)* (2016) (15)
- Combination of antiretroviral drugs as microbicides. (2012) (15)
- Inhibition of human IgE synthesis in vitro and in SCID-hu mice by an interleukin-4 receptor antagonist. (1995) (15)
- Selective activity of several cholic acid derivatives against human immunodeficiency virus replication in vitro. (1989) (15)
- IL-2 reverses human T cell unresponsiveness induced by thymic epithelium in SCID-hu mice. (1994) (15)
- Direct arylation of C60Cl6 and C70Cl8 with carboxylic acids: a synthetic avenue to water-soluble fullerene derivatives with promising antiviral activity. (2019) (15)
- Synthesis and evaluation of the biological activity of N′-[2-oxo-1,2 dihydro-3H-indol-3-ylidene] benzohydrazides as potential anticancer agents (2015) (15)
- Modest Human Immunodeficiency Virus Coreceptor Function of CXCR3 Is Strongly Enhanced by Mimicking the CXCR4 Ligand Binding Pocket in the CXCR3 Receptor (2007) (15)
- Synthesis of Novel Chiral Sulfonamide-Bearing 1,2,4-Triazole-3-thione Analogs Derived from D- and L-Phenylalanine Esters as Potential Anti-Influenza Agents. (2016) (15)
- Structure‐activity relationship studies on a Trp dendrimer with dual activities against HIV and enterovirus A71. Modifications on the amino acid (2017) (14)
- Development of a cell-based enzyme-linked immunosorbent assay for high-throughput screening of HIV type 1 entry inhibitors targeting the coreceptor CXCR4. (2003) (14)
- Extension of the polyanionic cosalane pharmacophore as a strategy for increasing anti-HIV potency. (1999) (14)
- Aspartate-Based CXCR4 Chemokine Receptor Binding of Cross-Bridged Tetraazamacrocyclic Copper(II) and Zinc(II) Complexes. (2016) (14)
- Amides of pyrrole- and thiophene-fused anthraquinone derivatives: A role of the heterocyclic core in antitumor properties. (2020) (14)
- Novel Recombinant Virus Assay for Measuring Susceptibility of Human Immunodeficiency Virus Type 1 Group M Subtypes To Clinically Approved Drugs (2009) (14)
- Development and in vitro evaluation of chloroquine gels as microbicides against HIV-1 infection (2008) (14)
- 64Cu PET Imaging of the CXCR4 Chemokine Receptor Using a Cross-Bridged Cyclam Bis-Tetraazamacrocyclic Antagonist (2020) (14)
- No Selection for CCR5 Coreceptor Usage during Parenteral Transmission of Macrophagetropic Syncytium-Inducing Human Immunodeficiency Virus Type 1 (2001) (13)
- Anti-HIV-active Nucleoside Triphosphate Prodrugs. (2020) (13)
- Advantages and shortcomings of cell-based electrical impedance measurements as a GPCR drug discovery tool. (2019) (13)
- Productive Infection of Primary Macrophages with Human Herpesvirus 7 (2001) (13)
- A SCAFFOLD SIMPLIFICATION STRATEGY LEADS TO A NOVEL GENERATION OF DUAL HUMAN IMMUNODEFICIENCY VIRUS AND ENTEROVIRUS-A71 ENTRY INHIBITORS. (2019) (13)
- Isolation and identification of naturally modified C-C chemokines MCP-1, MCP-2 and RANTES: effects of posttranslational modifications on receptor usage, chemotactic and anti-HIV-1 activity. (1998) (13)
- Novel halogenated 3-deazapurine, 7-deazapurine and alkylated 9-deazapurine derivatives of l-ascorbic or imino-l-ascorbic acid: Synthesis, antitumour and antiviral activity evaluations (2015) (12)
- Profile of Resistance of Human Immunodeficiency Virus to Mannose-Specific Plant Lectins (2004) (12)
- BAL neutrophilia in azithromycin-treated lung transplant recipients: Clinical significance. (2015) (12)
- Early identification of availability issues for poorly water-soluble microbicide candidates in biorelevant media: a case study with saquinavir. (2011) (12)
- New Isoxazolidine-Conjugates of Quinazolinones—Synthesis, Antiviral and Cytostatic Activity (2016) (12)
- Peripherally-driven myeloid NFkB and IFN/ISG responses predict malignancy risk, survival, and immunotherapy regime in ovarian cancer (2021) (12)
- Human Immunodeficiency Virus Type 1 Escape from Cyclotriazadisulfonamide-Induced CD4-Targeted Entry Inhibition Is Associated with Increased Neutralizing Antibody Susceptibility (2009) (12)
- Synthesis and the Biological Activity of Phosphonylated 1,2,3-Triazolenaphthalimide Conjugates (2016) (11)
- 4-(1-Adamantyl)phenylalkylamines with Potential Antiproliferative Activity (2016) (11)
- Design and cellular kinetics of dansyl-labeled CADA derivatives with anti-HIV and CD4 receptor down-modulating activity. (2007) (11)
- In vitro anti-HIV activity profile of AMD887, a novel CCR5 antagonist, in combination with the CXCR4 inhibitor AMD070 (2004) (11)
- The Phthalocyanine Prototype Derivative Alcian Blue Is the First Synthetic Agent with Selective Anti-Human Immunodeficiency Virus Activity Due to Its gp120 Glycan-Binding Potential (2009) (11)
- In vitro synergistic activity against CCR5-tropic HIV-1 with combinations of potential candidate microbicide molecules HHA, KRV2110 and enfuvirtide (T20). (2009) (11)
- Synthesis of a 3′-C-ethynyl-β-d-ribofuranose purine nucleoside library: Discovery of C7-deazapurine analogs as potent antiproliferative nucleosides (2018) (11)
- Mechanism of the Antiviral Activity of New Aurintricarboxylic Acid Analogues (1996) (11)
- Circulating Donor-Specific Anti-HLA Antibodies Associate With Immune Activation Independent of Kidney Transplant Histopathological Findings (2022) (11)
- Antiviral activity of carbohydrate-binding agents by interrupting the interaction between DC-SIGN and dengue virus (2009) (10)
- Design, synthesis and biological evaluation of 2-alkoxycarbonyl-3-anilinoindoles as a new class of potent inhibitors of tubulin polymerization. (2020) (10)
- Novel Isoxazolidine and γ-Lactam Analogues of Homonucleosides (2019) (10)
- Facile functionalization at the C4 position of pyrimidine nucleosides via amide group activation with (benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate (BOP) and biological evaluations of the products. (2017) (10)
- Griffithsin, Alone and Combined with All Classes of Antiretroviral Drugs, Potently Inhibits HIV Cell-Cell Transmission and Destruction of CD4+ T cells (2012) (10)
- Capture and transmission of HIV-1 by the C-type lectin L-SIGN (DC-SIGNR) is inhibited by carbohydrate-binding agents and polyanions. (2009) (10)
- Structural analogs of umifenovir 2*. The synthesis and antiHIV activity study of new regioisomeric (trans-2-phenylcyclopropyl)-1Н-indole derivatives (2015) (10)
- The antiviral activity of the CXCR4 antagonist AMD3100 is independent of the cytokine-induced CXCR4/HIV coreceptor expression level. (2003) (10)
- Aminomethylation of heliomycin: Preparation and anticancer characterization of the first series of semi-synthetic derivatives. (2018) (9)
- Diversion of the Arbuzov reaction: alkylation of C-Cl instead of phosphonic ester formation on the fullerene cage. (2019) (9)
- Development and Identification of a Novel Anti-HIV-1 Peptide Derived by Modification of the N-Terminal Domain of HIV-1 Integrase (2016) (9)
- Preprotein signature for full susceptibility to the co‐translational translocation inhibitor cyclotriazadisulfonamide (2020) (9)
- Targeted disruption of pi–pi stacking in Malaysian banana lectin reduces mitogenicity while preserving antiviral activity (2021) (9)
- Bis(benzoyloxybenzyl)‐DiPPro Nucleoside Diphosphates of Anti‐HIV Active Nucleoside Analogues (2015) (9)
- Simian Immunodeficiency Virus Is Susceptible to Inhibition by Carbohydrate-Binding Agents in a Manner Similar to That of HIV: Implications for Further Preclinical Drug Development (2008) (9)
- CXCR7/ACKR3-targeting ligands interfere with X7 HIV-1 and HIV-2 entry and replication in human host cells (2018) (9)
- Design, synthesis, in vitro antiproliferative activity and apoptosis-inducing studies of 1-(3′,4′,5′-trimethoxyphenyl)-3-(2′-alkoxycarbonylindolyl)-2-propen-1-one derivatives obtained by a molecular hybridisation approach (2018) (9)
- A porcine ex vivo lung perfusion model with maximal argon exposure to attenuate ischemia-reperfusion injury (2017) (9)
- CXC-Chemokine Receptor 4 Is Not a Coreceptor for Human Herpesvirus 7 Entry into CD4+ T Cells (2000) (9)
- Lung Microenvironments and Disease Progression in Fibrotic Hypersensitivity Pneumonitis. (2021) (8)
- Phosphonylated Acyclic Guanosine Analogues with the 1,2,3-Triazole Linker (2015) (8)
- A Flow Cytometry-based Assay to Identify Compounds That Disrupt Binding of Fluorescently-labeled CXC Chemokine Ligand 12 to CXC Chemokine Receptor 4. (2018) (8)
- Acetate as a model for aspartate-based CXCR4 chemokine receptor binding of cobalt and nickel complexes of cross-bridged tetraazamacrocycles. (2019) (8)
- A Novel Series of Indole Alkaloid Derivatives Inhibit Dengue and Zika Virus Infection by Interference with the Viral Replication Complex (2021) (8)
- Design and synthesis of pyridin-2-yloxymethylpiperidin-1-ylbutyl amide CCR5 antagonists that are potent inhibitors of M-tropic (R5) HIV-1 replication. (2011) (8)
- HIV-1 and Its Resistance to Peptidic Carbohydrate-Binding Agents (CBAs): An Overview (2014) (8)
- Water-soluble fullerene-based nanostructures with promising antiviral and myogenic activity. (2020) (8)
- Asymmetric Primaquine and Halogenaniline Fumardiamides as Novel Biologically Active Michael Acceptors (2018) (8)
- Thiophene-2-carboxamide derivatives of anthraquinone: A new potent antitumor chemotype. (2021) (8)
- Susceptibility of diverse primary HIV isolates with varying co‐receptor specificity's to CXCR4 antagonistic compounds (2002) (8)
- Virus-inhibitory peptide: a natural HIV entry inhibitor in search for a formal target in the viral genome. (2011) (8)
- Discovery of 3-phenyl- and 3-N-piperidinyl-isothiazolo[4,3-b]pyridines as highly potent inhibitors of cyclin G-associated kinase. (2021) (8)
- Inhibition of HIV-1-Induced Cytopathogenicity, Syncytium Formation, and Virus-Cell Binding by Naphthalenedisulphonic Acids through Interaction with the Viral Envelope gp120 Glycoprotein (1993) (8)
- Potent neutralizing anti-SARS-CoV-2 human antibodies cure infection with SARS-CoV-2 variants in hamster model (2021) (8)
- TIBO derivatives: a new class of highly potent and specific inhibitors of HIV-1 replication. (1992) (7)
- A patent review of adaptor associated kinase 1 (AAK1) inhibitors (2013-present) (2021) (7)
- HIV-1 gp 120 and chemokines activate ion channels in primary macrophages through CCR 5 and CXCR 4 stimulation (2000) (7)
- Improving potencies and properties of CD4 down-modulating CADA analogs (2012) (7)
- Synthesis and Ativiral Activity of 5-(Benzylthio)-4-carbamyl-1,2,3-triazoles Against Human Cytomegalovirus (CMV) and Varicella-zoster Virus (VZV). (2017) (7)
- Design, Synthesis, and the Biological Evaluation of a New Series of Acyclic 1,2,3‐Triazole Nucleosides (2017) (7)
- Synthesis and Bioactivity of Novel Trisubstituted Triazole Nucleosides (2016) (7)
- Assessment of protein biomarkers for preoperative differential diagnosis between benign and malignant ovarian tumors. (2020) (7)
- Iterative Chemical Engineering of Vancomycin Leads to Novel Vancomycin Analogs With a High in Vitro Therapeutic Index (2018) (7)
- Promising anti-HIV therapeutic strategy with a small molecule CXCR4 antagonist. (1999) (7)
- A unique class of lignin derivatives displays broad anti-HIV activity by interacting with the viral envelope. (2019) (7)
- Membrane permeable, bioreversibly modified Prodrugs of Nucleoside Diphosphate-γ-phosphonates. (2020) (7)
- Isoxazolidine Conjugates of N3-Substituted 6-Bromoquinazolinones—Synthesis, Anti-Varizella-Zoster Virus, and Anti-Cytomegalovirus Activity (2018) (7)
- A Short Hairpin Loop-Structured Oligodeoxynucleotide Targeting the Virion-Associated RNase H of HIV Inhibits HIV Production in Cell Culture and in huPBL-SCID Mice (2011) (7)
- Synthesis and Antiviral Activity of Water‐Soluble Polycarboxylic Derivatives of [60]Fullerene Loaded with 3,4‐Dichlorophenyl Units (2018) (7)
- X4 HIV-1 induces neuroblastoma cell death by interference with CXCL12/CXCR4 interaction. (2003) (7)
- CXCR4 is the primary receptor for feline immunodeficiency virus in astrocytes (2001) (7)
- Prodrugs of γ‐Alkyl‐Modified Nucleoside Triphosphates: Improved Inhibition of HIV Reverse Transcriptase (2020) (7)
- Coumermycin A1 is a potent inhibitor of human immunodeficiency virus (HIV) replication in vitro (1989) (7)
- Development of a Novel SPR Assay to Study CXCR4–Ligand Interactions (2020) (6)
- Profound Anti-HIV-1 Activity of DAPTA in Monocytes/macrophages and Inhibition of CCR5-mediated Apoptosis in Neuronal Cells (2007) (6)
- Innate Lymphoid Cells Are Required to Induce Airway Hyperreactivity in a Murine Neutrophilic Asthma Model (2022) (6)
- Synthesis and Antiviral Evaluation of TriPPPro‐AbacavirTP, TriPPPro‐CarbovirTP, and Their 1′,2′‐cis‐Disubstituted Analogues (2018) (6)
- Differential activity of candidate microbicides against early steps of HIV-1 infection upon complement virus opsonization (2010) (6)
- Restricted entry of R5 HIV Type 1 strains into eosinophilic cells. (2004) (6)
- Inhibition of Human Immunodeficiency Virus Replication by a Dual CCR 5 / CXCR 4 Antagonist (2004) (6)
- FO‐SPR biosensor calibrated with recombinant extracellular vesicles enables specific and sensitive detection directly in complex matrices (2021) (6)
- Synthesis, Anti-varicella-zoster virus and Anti-cytomegalovirus Activity of 4,5-Disubstituted 1,2,3-(1H)-Triazoles. (2019) (6)
- Combination of the CCL5-Derived Peptide R4.0 with Different HIV-1 Blockers Reveals Wide Target Compatibility and Synergic Cobinding to CCR5 (2014) (6)
- Specific interaction of aurintricarboxylic acid with the human immunodeficiency virus / CD 4 cell receptor ( acquired immunodeficiency syndrome / flow cytometry (6)
- Design, synthesis, and cytostatic activity of novel pyrazine sorafenib analogs (2016) (6)
- Discovery of ( ±)-3-(1 H -pyrazol-1-yl)-6,7-dihydro-5 H -[1,2,4]triazolo[3,4- b ][1,3,4] thiadiazine derivatives with promising in vitro anticoronavirus and antitumoral activity (2021) (6)
- Resistance profile of human immunodeficiency virus to CADA, a novel HIV inhibitor that targets the cellular CD4 receptor (2005) (6)
- Mitigating hERG Inhibition: Design of Orally Bioavailable CCR5 Antagonists as Potent Inhibitors of R5 HIV-1 Replication. (2012) (6)
- [Role of chemokines in the HIV infection process]. (2002) (6)
- Modifications in the branched arms of a class of dual inhibitors of HIV and EV71 replication expand their antiviral spectrum (2019) (6)
- Activity of different antiviral drug combinations against human cytomegalovirus replication in vitro (1992) (6)
- Small Molecule Cyclotriazadisulfonamide Abrogates the Upregulation of the Human Receptors CD4 and 4-1BB and Suppresses In Vitro Activation and Proliferation of T Lymphocytes (2021) (5)
- A Proteomic Study on the Membrane Protein Fraction of T Cells Confirms High Substrate Selectivity for the ER Translocation Inhibitor Cyclotriazadisulfonamide (2021) (5)
- Synthesis and Evaluations of “1,4‐Triazolyl Combretacoumarins” and Desmethoxy Analogs (2019) (5)
- Synthesis, characterization and anti-HIV activity of polycarboxylic [60]fullerene derivatives obtained in the reaction of C60Cl6 with a hydroquinone ether (2020) (5)
- CXCR4 Chemokine Receptor Antagonists from Ultra-rigid Metal Complexes Profoundly Inhibit HIV-1 Replication, and also AMD3100-resistant Strains (2009) (5)
- Multi-drug resistant HIV-1 is sensitive to inhibition by chemokine receptor antagonists (2005) (5)
- Metal complexes of pyridine-fused macrocyclic polyamines targeting the chemokine receptor CXCR4. (2015) (5)
- Synthesis of 2-[(ω-phthalimidoalkyl)sulfanyl]- pyrimidin-4(3H)-ones, their cytotoxicity and in vitro activity against HIV-1/2 (2020) (5)
- Design of substituted imidazolidinylpiperidinylbenzoic acids as chemokine receptor 5 antagonists: potent inhibitors of R5 HIV-1 replication. (2013) (5)
- Sliding of HIV-1 reverse transcriptase over DNA creates a transient P pocket – targeting P-pocket by fragment screening (2021) (5)
- Multivalent Tryptophan‐ and Tyrosine‐Containing [60]Fullerene Hexa‐Adducts as Dual HIV and Enterovirus A71 Entry Inhibitors (2021) (5)
- Novel isoxazolidine analogues of homonucleosides and homonucleotides (2016) (5)
- In Vitro Characterization of the Carbohydrate-Binding Agents HHA, GNA, and UDA as Inhibitors of Influenza A and B Virus Replication (2020) (5)
- Lipophilic Triphosphate Prodrugs of various Nucleoside Analogues. (2020) (5)
- Neo-Adjuvant Chemotherapy Reduces, and Surgery Increases Immunosuppression in First-Line Treatment for Ovarian Cancer (2021) (4)
- Deciphering the Role of Extracellular Vesicles Derived from ZIKV-Infected hcMEC/D3 Cells on the Blood–Brain Barrier System (2021) (4)
- Diastereoselective Synthesis of (1,3‐Dioxan‐4‐yl)pyrimidine and Purin Nucleoside Analogues (2015) (4)
- Synthesis of Novel Thiopurine Pyranonucleosides: Evaluation of Their Bioactivity (2015) (4)
- CADA, a Potential Anti-HIV Microbicide that Specifically Targets the Cellular CD4 Receptor (2009) (4)
- New [4,5,1-JK][1,4]benzodiazepin-2(1H)-one and -thione derivatives are potent inhibitors of human immunodeficiency virus type 1 and are synergistic with 2',3'-dideoxynucleoside analogs (1994) (4)
- A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators. (2018) (4)
- Exploring the purine core of 3′-C-ethynyladenosine (EAdo) in search of novel nucleoside therapeutics (2016) (4)
- Design, synthesis and antiviral evaluation of novel acyclic phosphonate nucleotide analogs with triazolo[4,5-b]pyridine, imidazo[4,5-b]pyridine and imidazo[4,5-b]pyridin-2(3H)-one systems (2020) (4)
- Polyfunctionalized Pyrrole Derivatives: Easy Three-component Microwave-assisted Synthesis, Cytostatic and Antiviral Evaluation (2018) (4)
- Double Arylation of the Indole Side Chain of Tri- and Tetrapodal Tryptophan Derivatives Renders Highly Potent HIV-1 and EV-A71 Entry Inhibitors (2021) (4)
- Characterization of vertebrate peptide hormone-like materials in the American cockroach: different methods employed to investigate these substances and their results (1986) (4)
- Correction: Facile functionalization at the C4 position of pyrimidine nucleosides via amide group activation with (benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate (BOP) and biological evaluations of the products. (2017) (4)
- Identification of novel chemotypes as CXCR2 antagonists via a scaffold hopping approach from a thiazolo[4,5-d]pyrimidine. (2022) (4)
- Synthesis of Enantiomerically Pure 1′,2′-cis-dideoxy, -dideoxydidehydro, -ribo and -deoxy Carbocyclic Nucleoside Analogues (2018) (4)
- Tryptophan Trimers and Tetramers Inhibit Dengue and Zika Virus Replication by Interfering with Viral Attachment Processes (2020) (4)
- Peroxynitrite Exposure of CXCL12 Impairs Monocyte, Lymphocyte and Endothelial Cell Chemotaxis, Lymphocyte Extravasation in vivo and Anti-HIV-1 Activity (2018) (4)
- Unsung Hero Robert C. Gallo (2009) (4)
- CXCR4 Antagonists: A New Generation of Configurationally Restricted Bis-azamacrocyclic Compounds (2009) (4)
- The discovery of Zika virus NS2B-NS3 inhibitors with antiviral activity via an integrated virtual screening approach. (2022) (4)
- Phosphonylated 8-Azahypoxantines as Acyclic Nucleotide Analogs (2015) (3)
- An easy microwave-assisted synthesis of C8-alkynyl adenine pyranonucleosides as novel cytotoxic antitumor agents (2015) (3)
- Early protein expression profile in bronchoalveolar lavage fluid and clinical outcomes in primary graft dysfunction after lung transplantation. (2020) (3)
- SARS-CoV-2 Virion Infectivity and Cytokine Production in Primary Human Airway Epithelial Cells (2022) (3)
- Synthesis of Stilbene-Based Resveratrol Analogs as Cytotoxic Agents (2016) (3)
- Water-Promoted Reaction of C60Ar5Cl Compounds with Thiophenes Delivers a Family of Multifunctional Fullerene Derivatives with Selective Antiviral Properties. (2021) (3)
- Some Features of the Tscherniac‒Einhorn Reaction with 2-Thiouracil Derivatives (2020) (3)
- Labyrinthopeptin A1 inhibits dengue and Zika virus infection by interfering with the viral phospholipid membrane. (2021) (3)
- The role of cytokines in transplantation tolerance (1995) (3)
- Skeleton binding protein-1-mediated parasite sequestration inhibits spontaneous resolution of malaria-associated acute respiratory distress syndrome (2021) (3)
- Synthesis and Anti‐HIV Activity of Guanine Modified Fluorinated Acyclic Nucleoside Phosphonate Derivatives (2019) (3)
- Active Components from Cassia abbreviata Prevent HIV-1 Entry by Distinct Mechanisms of Action (2021) (3)
- Synthesis, in silico ADME, molecular docking and in vitro cytotoxicity evaluation of stilbene linked 1,2,3-triazoles (2021) (3)
- Itaconic acid hybrids as potential anticancer agents (2020) (3)
- Synthesis, in vitro cytotoxicity, molecular docking and ADME study of some indolin-2-one linked 1, 2, 3-triazole derivatives (2022) (3)
- CC Chemokine Receptor 3 Human Eotaxin by Affecting Its Interaction Potency , But Not the Anti-HIV Activity of Down-Regulates the Eosinophil Chemotactic CD 26 / Dipeptidyl-Peptidase IV (1999) (3)
- Synthesis, Molecular Docking and Preliminary Antileukemic Activity of 4‐Methoxybenzyl Derivatives Bearing Imidazo[2,1‐b][1,3,4]thiadiazole (2020) (3)
- Discovery of 2-Phenylquinolines with Broad-Spectrum Anti-coronavirus Activity (2022) (3)
- Thiophene-based water-soluble fullerene derivatives as highly potent antiherpetic pharmaceuticals. (2020) (2)
- Internal Disulfide Bonding and Glycosylation of Interleukin-7 Protect Against Proteolytic Inactivation by Neutrophil Metalloproteinases and Serine Proteases (2021) (2)
- Virus resistance to the CXCR4 inhibitor AMD070 develops slowly and does not induce a co-receptor switch (2004) (2)
- An efficient one-pot conversion of Boc-protected adenines to N-6-ureas (2015) (2)
- Design and synthesis of pyridin-2-ylmethylaminopiperidin-1-ylbutyl amide CCR5 antagonists that are potent inhibitors of M-tropic (R5) HIV-1 replication. (2011) (2)
- Live biotherapeutic throat spray for respiratory virus inhibition and interferon pathway induction (2022) (2)
- Chemotherapy of human immunodeficiency virus by pradimicin A: a novel therapeutic concept for treatment of glycosylated enveloped viruses (2006) (2)
- Dual anti-HSV and anti-HIV activity of the lantibiotic Labyrinthopeptin A1 (2014) (2)
- 1H)-One and-Thione Derivatives ArePotent Inhibitors ofHuman Immunodeficiency Virus Type1Replication andAre Synergistic with2',3'-Dideoxynucleoside Analogs (1994) (2)
- Carbohydrate-Binding Agents (CBAs) Selectively Target the Glycoproteins of the HCV and HIV Envelope to Prevent Viral Entry (2007) (2)
- Selective inhibition of CD4 protein translocation and cell surface expression as a novel tool for preventing HIV infection (2010) (2)
- In vitro synergy between the CD4 down-modulating compound, CADA, and multiple anti-HIV drugs (2003) (2)
- In silico design, synthesis and anti-HIV activity of quinoline derivatives as non-nucleoside reverse transcriptase inhibitors (NNRTIs) (2022) (2)
- VCH-286, a novel CCR5 antagonist: binding kinetics, anti-HIV activity and in vitro combination studies (2009) (2)
- Erratum: Viral entry as the primary target for the anti-HIV activity of chicoric acid and its tetraacetyl esters (Molecular Pharmacology (2000) 58 (641-648)) (2001) (2)
- Broad Antiviral Activity of Carbohydrate-Binding Agents Against Dengue Virus Infection (2012) (2)
- Cellular receptors as targets for anti-human immunodeficiency virus agents (2001) (2)
- Novel N-Substituted 3-Aryl-4-(diethoxyphosphoryl)azetidin-2-ones as Antibiotic Enhancers and Antiviral Agents in Search for a Successful Treatment of Complex Infections (2021) (2)
- Copper-64 PET imaging of the CXCR4 chemokine receptor using a cross-bridged cyclam bis-tetraazamacrocyclic antagonist (2019) (2)
- Synthesis, antiviral, cytotoxic and cytostatic evaluation of N1-(phosphonoalkyl)uracil derivatives (2016) (2)
- Exploring the dNTP -binding site of HIV-1 reverse transcriptase for inhibitor design. (2021) (2)
- Design, Synthesis, and Biological Evaluation of Novel C5-Modified Pyrimidine Ribofuranonucleosides as Potential Antitumor or/and Antiviral Agents. (2020) (2)
- γ‐Non‐Symmetrically Dimasked TriPPPro Prodrugs as Potential Antiviral Agents against HIV (2020) (2)
- Microvirin, a novel α(1,2)-mannose-specific lectin isolated from Microcystis aeruginosa, has potent anti-HIV-1 activity (2010) (2)
- Development of new potent and selective agents against HIV (human immunodeficiency virus). (1991) (2)
- Synthesis and antiviral properties of new derivatives of 2-(alkylsulfanyl)-6-[1-(2,6-difluorophenyl)cyclopropyl]-5-methylpyrimidin-4(3H)-one (2016) (2)
- HIV coreceptor CXCR4 antagonists (2006) (2)
- Effect of Particle Carriers for Intraperitoneal Drug Delivery on the Course of Ovarian Cancer and Its Immune Microenvironment in a Mouse Model (2022) (2)
- Carbohydrate-binding protein from stinging nettle as fusion inhibitor for SARS-CoV-2 variants of concern (2022) (2)
- SYNTHESIS OF IMIDAZO[2,1-b][1,3,4]THIADIAZOLE DERIVATIVES AS POSSIBLE BIOLOGICALLY ACTIVE AGENTS. (2016) (2)
- Acyclic nucleoside phosphonates containing the amide bond (2016) (2)
- Expedient synthesis and biological evaluation of alkenyl acyclic nucleoside phosphonate prodrugs (2018) (2)
- Pradimicin S, a highly-soluble non-peptidic small-size carbohydrate-binding antibiotic, (2010) (2)
- SYNTHESIS AND PHARMACOLOGICAL ACTIVITY OF IMIDAZO[2,1- b][1,3,4]THIADIAZOLE DERIVATIVES. (2016) (1)
- Feglymycin, a Unique 13 Amino-acid Peptide, With a Novel Mechanism of Anti-HIV-1 Activity (2009) (1)
- HIV-1 transcription in vivo-1-1 2 A NOVEL IN VIVO MODEL FOR THE STUDY OF HIV-1 3 TRANSCRIPTION INHIBITORS : EVALUATION OF NEW 4 6-DESFLUOROQUINOLONE DERIVATIVES ( 6-DFQs ) 5 6 7 (2007) (1)
- A novel experimental porcine model to assess the impact of differential pulmonary blood flow on ischemia–reperfusion injury after unilateral lung transplantation (2020) (1)
- Biological characterization of ligands targeting the human CC chemokine receptor 8 (CCR8) reveals the biased signaling properties of small molecule agonists. (2021) (1)
- Branched-chain sugar nucleosides: stereocontrolled synthesis and bioevaluation of novel 3'-C-trifluoromethyl and 3'-C-methyl pyranonucleosides. (2015) (1)
- Different evolution and patterns of genotypic resistance profiles in emtricitabine plus tenofovir and lamivudine plus tenofovir containing regimen (2009) (1)
- Interaction of TIBO and TIBO-like compounds with HIV-1 RT (1991) (1)
- An Efficient One‐Pot Conversion of Boc‐Protected Adenines to N6‐Ureas. (2016) (1)
- PRO 2000, a broadly active anti-HIV sulfonated compound, inhibits viral entry by multiple mechanisms (2010) (1)
- Synergistic anti-HIV-1 activity of griffithsin with tenofovir, maraviroc and enfuvirtide (2011) (1)
- In-Depth Characterization of Zika Virus Inhibitors Using Cell-Based Electrical Impedance (2022) (1)
- Development and in vitro evaluation of gel-formulated saquinavir as vaginal microbicide: anti-HIV-1 activity and pharmaceutical availability in biorelevant media (2010) (1)
- Design and synthesis of a new series of hybrids of functionalised N1-[(1H-1,2,3-triazol-4-yl)methyl]quinazoline-2,4-dione with antiviral activity against Respiratory Syncytial Virus. (2022) (1)
- Synthesis of Novel CADA Analog Prodrugs Designed as Down-Modulators of the CD4 Receptor (2010) (1)
- CADA compounds: inhibitors of HIV and HHV-7 replication via down-modulation of CD4 receptor expression (2001) (1)
- SRR-SB 3 , a Disulfide-Containing Macrolide That Inhibits a Late Stage of the Replicative Cycle of Human Immunodeficiency Virus (1997) (1)
- Diffusion of Two Potential Anti-HIV Microbicides across Intact and De-Epithelialised, Human Vaginal Mucosa (2008) (1)
- Potent and selective inhibition of HIV-1 and HIV-2 replication by a novel class of bicyclams targeted at viral uncoating (1992) (1)
- Facile Microwave-assisted Synthesis of Various C5-modified Pyrimidine Pyranonucleosides as Potential Cytotoxic Antitumor Agents (2017) (1)
- Heterocyclic compounds binding chemokine receptor with enhanced efficacy (2002) (1)
- Mannose-specific plant lectins as potential HIV microbicides (2004) (1)
- Development of a live biotherapeutic throat spray with lactobacilli targeting respiratory viral infections (2022) (1)
- Synthesis and evaluation of 3-alkynyl-5-aryl-7-aza-indoles as broad-spectrum antiviral agents (2022) (1)
- γ-Ketobenzyl-Modified Nucleoside Triphosphate Prodrugs as Potential Antivirals. (2020) (1)
- POSTER VIEWING SESSION - ENDOMETRIOSIS, ENDOMETRIUM, IMPLANTATION AND FALLOPIAN TUBE (2011) (1)
- Influence of initial conditions on the development of resistance to TIBO derivatives in cell culture (1992) (1)
- NH2-terminal processing of chemokines (RANTES, SDF1-alpha) by CD26/dipeptidylpeptidase IV generates inhibitors of chemotaxis and HIV-1 infection (1998) (1)
- Quantitative label-free nanoscale LC-MS analysis of HIV drug-treated human T-cell cultures (2006) (1)
- A Set of Experimentally Validated Decoys for the Human CC Chemokine Receptor 7 (CCR7) Obtained by Virtual Screening (2022) (1)
- Escherichia coli K5 polysaccharide derivatives inhibit dengue virus infection of human microvascular endothelial cells by interacting with the viral envelope domain III (2013) (1)
- Antiviral, cytostatic and cytotoxic activity of plant lectins in co-cultures of monocyte derived dendritic cells (MO-DC) and CD4+ T cells as representative target cells for sexual HIV transmission (2006) (1)
- Endocrine-cells in the midgut of the cockroach periplaneta-americana l - an immunohistochemical study (1987) (1)
- Cytotoxicity studies of primaquine and chloroquine fumardiamides (2019) (1)
- Carbohydrate-binding agents (CBAs) potently inhibit HIV infection in human primary monocytes/macrophages and efficiently prevent viral capture and subsequent transmission to CD+4 T lymphocytes (2007) (1)
- The Role of B-Cells in Phenotypes of Chronic Lung Allograft Dysfunction (2015) (1)
- Palladium-catalyzed cross-coupling reactions on a bromo-naphthalene scaffold in the search for novel human CC chemokine receptor 8 (CCR8) antagonists. (2020) (1)
- SYNTHESIS AND CYTOTOXIC EVALUATION OF SOME 2-{4-[(2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)METHYL] PHENOXY}-N-PHENYLACETAMIDE. (2017) (1)
- Targeting chemokine receptors from the inside-out: discovery and development of small-molecule intracellular antagonists. (2022) (1)
- 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide (ribavirin) and 5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide (EICAR) markedly potentiate the inhibitory effect of 2',3'-dideoxyinosine on human immunodeficiency virus in peripheral blood lymphocytes. (1991) (1)
- Lignosulfonic acid exhibits broad-spectrum anti-HIV and anti-HSV activity and has potential for microbicidal applications (2014) (1)
- Anti-HIV activity profile of a novel CCR5 inhibitor, AMD887, in combination with the CXCR4 inhibitor AMD070 (2004) (1)
- Synthesis and Anti-HIV Activity of a Novel Series of Isoquinoline-Based CXCR4 Antagonists (2021) (1)
- Synthesis, molecular docking, and preliminary cytotoxicity study of some novel 2-(naphthalen-1-yl)-methylimidazo[2,1-b][1,3,4]thiadiazoles (2021) (1)
- Anthranilamides with quinoline and β-carboline scaffolds: design, synthesis, and biological activity (2022) (1)
- Labyrinthopeptin A1, a novel lantibiotic peptide, is a dual HIV and HSV entry inhibitor (2013) (1)
- Synthesis and structure-activity relationships of the novel isothiobarbamine analogues with lowered basicity (2020) (1)
- A small-molecule inhibitor of CD4 protein translocation down-modulates the primary HIV receptor (2011) (1)
- Corrigendum to ‘Discovery of HIV entry inhibitors via a hybrid CXCR4 and CCR5 receptor pharmacophore-based virtual screening approach’ [European Journal of Pharmaceutical Sciences 155 (2020) 105537] (2021) (1)
- Acyclic nucleoside phosphonates containing the amide bond: hydroxy derivatives (2019) (1)
- The Twenty-Second International Conference on Antiviral Research (2009) (1)
- Antiviral activity of carbohydrate binding agents (CBAS) and the role of DC-SIGN in Dengue virus and HIV infection (2009) (1)
- Mannose-specific plant lectins may qualify as efficient microbicides against human immunodeficiency virus transmission (2002) (1)
- The orally bioavailable allosteric CXCR4 HIV-1 entry inhibitor AMD11070 (2012) (1)
- Human T-cell development in SCID-hu mice (1995) (1)
- D-Peptide-Based Probe for CXCR4-Targeted Molecular Imaging and Radionuclide Therapy (2021) (1)
- Potent and highly selective HIV-1 specific inhibition by a new series of alfa- anilino-phenylacetamide (alfa-APA) derivatives targeted at HIV-1 RT (1992) (1)
- CADA inhibits HIV and HHV-7 replication by down-modulation of the cellular CD4 receptor (2001) (1)
- Negatively charged albumins exhibit a potent invitro anti-HIV-1 activity and a unique inhibitory action on syncytium formation (1991) (0)
- HIV-CD4 interaction as target for anti-HIV agents (1990) (0)
- Insertion of an Amphipathic Linker in a Tetrapodal Tryptophan Derivative Leads to a Novel and Highly Potent Entry Inhibitor of Enterovirus A71 Clinical Isolates (2023) (0)
- Preparation and Anti‐HIV Activity of O‐Acylated Heparin and Dermatan Sulfate Derivatives with Low Anticoagulant Effect. (2010) (0)
- Evaluation of CXCR4 inhibitors by FLIPR and flow cytometric techniques (2002) (0)
- The TIBO-site on HIV-1 reverse transcriptase represents a new target for anti-HIV chemotherapy (1991) (0)
- In search of novel nucleoside therapeutics: exploring the purine core of 3'-C-ethynyladenosine (2015) (0)
- Prevention of HIV transmission and SIV infection by specifically targeting CD4 (2008) (0)
- Microvirin a novel carbohydrate binding lectin with potent anti-HIV-1 activity (2011) (0)
- Interactions of the HIV fusion inhibitor AR177 (ZINTEVIR) with the HIV type I second receptor (1997) (0)
- Triphosphate Prodrugs of the Anti-HIV-Active Compound 3'-Deoxy-3'-fluorothymidine (FLT). (2022) (0)
- Synergistic activity of griffithsin in combination with tenofovir, maraviroc and enfuvirtide against HIV-1 subtype C (2011) (0)
- Development of new anti-HIV agents and elucidation of their mechanism of action (1990) (0)
- Synthesis of CADA Analog Prodrugs Designed as Novel Down-modulators of the CD4 Receptor (2009) (0)
- Brain and gastro-intestinal peptides of the vertebrate-type in the American cockroach Periplaneta americana L. Three complementary approaches (1986) (0)
- Resistance development of human immunodeficiency virus by plant lectins from the Amaryllidaceae family (2003) (0)
- Session 05: Endometriosis: Impact, Diagnosis and Surgery (2010) (0)
- Design and cellular kinetics of dansyl-labeled CADA derivatives with specific anti-HIV and CD4 receptor down-modulating properties (2007) (0)
- Itaconic acid hybrids as potential anticancer agents (2020) (0)
- Receptor MDCChemokine ( MDC ) Imply an Additional-Terminally Processed Macrophage-Derived 2 and Altered Chemotactic Potency of NH Cutting Edge : Enhanced Anti-HIV-1 Activity (1998) (0)
- Blockade of HIV transmission and SIV infection with CADA, a candidate microbicide that specifically targets the cellular CD4 receptor (2007) (0)
- Evaluation of chemokine receptor antagonists: comparing FLIPR and flow cytometric techniques (2002) (0)
- Chemotherapeutic targeting of the glycans on the viral envelope as a tool to prevent viral entry and transmission (2008) (0)
- Mutagenic analysis of the preprotein signal sequence of the cellular HIV-1 receptor CD4, a unique target for CD4 down-modulating agents (2011) (0)
- Abstracts of papers Symposium “new therapeutic developments in human infectious diseases” (1989) (0)
- Synthesis of new riboflavin modified ODNs: Effect of riboflavin moiety on the G-quadruplex arrangement and stability. (2020) (0)
- Systemic cytokines and GlycA discriminate disease status and predict corticosteroid response in HTLV-1-associated neuroinflammation (2022) (0)
- Carbohydrate-binding agents, but not polyanions efficiently prevent HIV-1 capture by DC-SIGN-expressing cells and subsequent virus transmission to CD4+ T-lymphocytes (2007) (0)
- Anti-HIV Agents Interfering with the Viral gp120-Cellular CD4 Interaction (1992) (0)
- Immunoregulatory effects of multipotent adult progenitor cells in a porcine ex vivo lung perfusion model (2017) (0)
- The live cell image JuLITM analyser as a useful tool for studying HIV cell-cell transmission (2012) (0)
- The orally bioavailable allosteric CXCR4 HIV-1 entry inhibitor AMD11070 (2012) (0)
- Triphosphate prodrugs (trippro's) of biologically active nucleosides (2015) (0)
- [Lasting neurologic injury in therapeutic lithium plasma levels]. (1989) (0)
- Potential chemotherapeutic targets in the replicative cycle of HIV (1994) (0)
- Labyrinthopeptins - New lantibiotics with broad antiviral activity (2015) (0)
- Effect of Head Group Variation on Human CD4 Down-Modulating and Anti-HIV Potencies of CADA Analogs (2014) (0)
- Beta-arrestin 2 recruitment by GPCRs using NanoBiT and NanoBRET combined with FLIPR Tetra technology focusing on the G protein-independent chemokine receptor ACKR3/CXCR7 (2017) (0)
- Flow cytometric/fluorometric assays for the evaluation of the anti-HIV activity of chemokine receptor inhibitors (2005) (0)
- Broad-spectrum antiviral activity of polyoxometalates against human immunodeficiency virus and other enveloped viruses (1992) (0)
- Co-translational translocation of human sortilin into the ER lumen is inhibited by cyclotriazadisulfonamide (2017) (0)
- Novel synthesized compounds with ‘viologen’ skeleton have anti‐HIV‐1 activity and interfere with the HIV‐1 coreceptor CXCR4 (2011) (0)
- Identification of angiogenic factors that mediate dengue virus-induced vascular permeability (2011) (0)
- Bicyclams: selective CXCR4 antagonists with potent anti-HIV activity (1997) (0)
- Peptide hormone immunocytochemistry in insects (1987) (0)
- Effects of Sidearm Substituents in Unsymmetrical Cyclotriazadisulfonamide (CADA) Analogs on Anti-HIV and Human CD4 Down-Modulating Abilities (2014) (0)
- Dansyl-tagged CADA derivatives with specific anti-HIV and CD4 receptor downmodulating properties (2007) (0)
- Residues in the hydrophobic signal peptide region and charges at the amino-terminus of the mature human CD4 protein region contribute to CADA sensitivity (2016) (0)
- A novel CD4 down-modulating compound with antiviral activity (2001) (0)
- Synthesis of novel CADA analog prodrugs designed to act as anti-HIV agents via down-modulation of the CD4 receptor (2012) (0)
- A small-molecule HIV entry inhibitor selectively inhibits co-translational translocation of CD4 into the endoplasmic reticulum (2013) (0)
- Discovery of inhibitors for the human chemokine receptors CXCR4 and CXCR7: screening applications on the FLIPR Tetra high-throughput cellular screening system (2016) (0)
- CADA, a novel antiretroviral drug with specific CD4 down-modulating activity (2002) (0)
- Pentosan polysulfate in HIV patients: a phase I study (1990) (0)
- Exploration of Pyrido[3,4-d]pyrimidines as Antagonists of the Human Chemokine Receptor CXCR2 (2023) (0)
- The non-peptidic mannose-binding pradimycin antibiotics inhibit HIV infection, viral capture by DC-SIGN, and viral transmission to T-lymphocytes (2007) (0)
- Cyclotriazadisulfonamide (CADA) compounds, HIV entry inhibitors that specifically target the cellular CD4 receptor (2006) (0)
- HIV-1 integrase is transported to the nucleus when expressed as a fusion protein with GFP (1999) (0)
- C-3’-ethynylnucleosides: an old modification going viral (2016) (0)
- Purine-mimicking 3’-ethynylribofuranose nucleosides : new opportunities for an old sugar modification (2016) (0)
- Pradimicin-S is a highly soluble non-peptidic small-size carbohydrate-binding antibiotic that may qualify as a potential drug lead for HIV treatment (2009) (0)
- A Novel Small-molecule CCR5 Agonist, ESN-196, with Potent R5 HIV-1 Activity (2009) (0)
- Resistance profile of human immunodeficiency virus to mannose-binding proteins (2004) (0)
- Synthesis and anticancer activity of 6-aryl-2-naphthyl-imidazo[2,1 b][1,3,4]thiadiazole (2017) (0)
- Synthesis of Anti-HIV CADA Compounds and Quantitative Structure-Activity Relationships for CD4 Down-Modulation (2003) (0)
- Resistance development of human immunodeficiency virus type 1 towards mannose-specific plant lectins in cell culture (2003) (0)
- Purification of natural CXCL12 – Characterisation of posttranslationally modified forms (2014) (0)
- Citrullination of CXCL12 affects its inflammatory and anti-HIV-1 activity (2009) (0)
- Natural CXCL12 nitration reduces its receptor signaling, chemotactic and anti-HIV activity (2014) (0)
- CADA, a small-molecule HIV inhibitor, selectively inhibits co-translational translocation of the human CD4 receptor into the endoplasmic reticulum (ER) (2012) (0)
- CAN WE ATTENUATE ISCHEMIA-REPERFUSION INJURY OF ALLOGRAFTS IN A PORCINE LEFT LUNG TRANSPLANT MODELS BY ADSORPTION OF CYTOKINES? (2022) (0)
- CADA, a specific CD4 down-modulating compound with potent anti-HIV activity (2002) (0)
- The anti-HIV and anti-HHV-7 potency of CADA analogs is strictly correlated with their ability to down-modulate the CD4 receptor (2002) (0)
- Insights into biological activity of SAHAquines, hybrids based on SAHA and aminoquinoline motifs (2018) (0)
- Signal peptide-binding drug inhibits cell surface CD4 receptor expression for HIV-1 attachment and entry (2014) (0)
- Combination of the candidate microbicide CADA, an entry inhibitor that specifically targets the cellular CD4 receptor, and cellulose acetate 1,2-benzenedicarboxylate have synergistic effects against HIV infection (2006) (0)
- Unsymmetrical CADA Analogs as Novel Down-modulators of the CD4 Receptor (2009) (0)
- Development of novel therapeutic concepts and rational anti-HIV drug design (2006) (0)
- Pradimicin antibiotics prevent HIV infection, viral capture by DC-SIGN and viral transmission to T-lymphocytes (2008) (0)
- The anti-HIV prokaryotic lectin, cyanovirin-N (CV-N), but not several other lectins such as HHA, GNA and UDA induces activation and production of cytokines (2008) (0)
- Visible-Light-Promoted Tandem Thiol-Ene Click Reaction/Transannular Cyclization and Regioselective Cyclopropane Ring-Opening to Construct Sulfur-Containing Euphorbia Diterpenes. (2023) (0)
- In vitro evaluation of chloroquine gels against HIV-1 infection (2008) (0)
- Optimizing the unsymmetrical structure of benzyl-tailed CADA analogs to improve their CD4 down-modulating and anti-HIV activity (2013) (0)
- DC-SIGN: An important attachment receptor for dengue virus and for development of antiviral therapy with carbohydrate-binding agents (2010) (0)
- GPCR cell-based fluorescence assays using the Fluorescence Imaging Plate Reader (FLIPR) Tetra (2015) (0)
- Contents list. (2017) (0)
- In vitro evaluation of gel-formulated saquinavir as vaginal microbicide: pharmaceutical availability in biorelevant media and anti-HIV-1 activity (2008) (0)
- SYNTHESIS AND PHARMACOLOGICAL ACTIVITY OF IMIDAZO[2,1- b][1,3,4]THIADIAZOLE DERIVATIVES. (2016) (0)
- TlBO derivatives : a new class of highly potent and specific inhibitors of HIV-I replication (2009) (0)
- Griffithsin, in combination with all ARV drugs, potently inhibits HIV cellular transmission and destruction of target CD4 T cells (2013) (0)
- Resistance profile of HIV-1 to the broadly neutralizing anti-gp120 2G12 antibody (2006) (0)
- A new class of dual HIV and EV71 entry inhibitors: tri and tetrapodal tryptophan derivatives (2019) (0)
- Switch in Coreceptor Use the Envelope gp120 but Does Not Show a Contains Mutations in α Cell-Derived Factor 1 Virus Type 1 That Is Made Resistant to Stromal T-Cell-Line-Tropic Human Immunodeficiency (2013) (0)
- Targeted disruption of pi–pi stacking in Malaysian banana lectin reduces mitogenicity while preserving antiviral activity (2021) (0)
- Vertebrate-type brain and gastrointestinal peptides in periplaneta, sarcophaga, locusta and crangon - the immunocytochemical approach (1986) (0)
- Targeting the dengue virus envelope protein by Escherichia coli K5 derivatives to inhibit the infection of microvascular endothelial cells (2013) (0)
- Cryo-EM structures of wild-type and E138K/M184I mutant HIV-1 RT/DNA complexed with inhibitors doravirine and rilpivirine (2022) (0)
- Potent and highly selective HIV-1 specific inhibition by a new series of phenylacetamide derivatives targeted at HIV-1 RT (1992) (0)
- Long-Lasting Enfuvirtide Carrier Pentasaccharide Conjugates with Potent Anti-Human Immunodeficiency Virus Type 1 Activity (cid:1) (2009) (0)
- The non-peptidic carbohydrate-binding pradimycin antibiotics inhibit HIV infection, viral capture by DC-SIGN, and viral transmission and thus may qualify as potential microbicide candidate drugs (2008) (0)
- Profile of Resistance of Human Immunodeficiency Virus to Mannose-Specific Plant Lectins (2004) (0)
- Cellular Electrical Impedance as a Method to Decipher CCR7 Signalling and Biased Agonism (2022) (0)
- Anti-HIV macrocyclic polyamines targeting cellular chemokine receptors CXCR4 and CCR5 (2009) (0)
- A regioselective step-by-step C60Cl6 functionalization approach affords a novel family of C60Ar5Th'Th''H fullerene derivatives with promising antiviral properties. (2023) (0)
- Proopiomelanocortin-related substances and a crf-like peptide in the midgut of the cockroach, periplaneta-americana (1987) (0)
- Synthesis and quantitative structure-activity relationships of CADA compounds having anti-HIV and CD4 down-modulation activities (2005) (0)
- In vitro resistance development of human immunodeficiency virus type 1 towards mannose-specific plant lectins (2003) (0)
- Correlation between the anti-HIV potency of CADA derivatives and their ability to down-modulate the CD4 receptor (2002) (0)
- Broad-spectrum anti-HIV activity of griffithsin and synergy with the antiretroviral drugs maraviroc, tenofovir and raltegravir (2012) (0)
- ALBUMIN CAN BE MODIFIED TO AN EXTREMELY POTENT INHIBITOR OF HIV REPLICATION WITH SPECIFIC EFFECTS ON LYMPHOCYTE-T4-VIRUS FUSION AND SYNCYTIUM FORMATION (1991) (0)
- CXCR4 and ACKR3 binding azamacrocyclic compounds for targeted PET imaging and therapeutic applications in cancer. (2019) (0)
- Human Immunodeficiency Virus Type 1 Escape from Cyclotriazadisulfonamide-Induced CD4-Targeted Entry Inhibition Is Associated with Increased Neutralizing Antibody Susceptibility (cid:1) (2009) (0)
- Immunological Overlap Between Rejection and Infection in Murine Lung Transplantation (2023) (0)
- CXCR 4 chemokine receptor antagonists : nickel ( II ) complexes of con fi gurationally restricted macrocycles † (2012) (0)
- Synthesis, anti-HIV and CD4 down-modulation activities of novel CADA compounds (2007) (0)
- Macrocyclic Polyamines Targeting the Cellular HIV Co-receptors, CXCR4 and CCR5 (2009) (0)
- TIBO derivatives represent a new lead of potent and selective HIV-1 inhibitors that interact with a reverse transcriptase-associated process (1990) (0)
- Identification of chlorocarbazole derivatives as potential antiviral agents. (2018) (0)
- Plant lectins are carbohydrate-binding agents that qualify as potential microbicide drugs (2006) (0)
- Organotropic dendrons with high potency as HIV-1, HIV-2 and EV-A71 cell entry inhibitors. (2022) (0)
- The anti-HIV activity of the CXCR4 inhibitor AMD3100 is independent of the CXCR4/HIV coreceptor level (2003) (0)
- Mac-1+ cells as effector cells in the collagen-induced arthritis in IFN-gamma receptor knockout and wild-type mice (2003) (0)
- CXCR4 antagonists as HIV entry inhibitors (2001) (0)
- FLUIDOT: A Modular Microfluidic Platform for Single‐Cell Study and Retrieval, with Applications in Drug Tolerance Screening and Antibody Mining (2023) (0)
- PRO 2000, a broadly active anti-HIV sulfonated compound, inhibits HIV infection by multiple mechanisms (2009) (0)
- 229: Dengue virus infection and induction of proinflammatory cytokines in dendritic cells is profoundly inhibited by selective carbohydrate-binding agents (CBAs) (2013) (0)
- Simultaneous inhibition of human CD4 and 4-1BB biogenesis suppresses cytotoxic T lymphocyte proliferation (2021) (0)
- Correlation between side arm dipole moments and human CD4 down-modulating abilities in unsymmetrical cyclotriazadisulfonamide (CADA) compounds with anti-HIV activities (2015) (0)
- Glycopeptide antibiotic derivatives selectively inhibit human immunodeficiency virus replication in cell culture (2003) (0)
- Cytostatic activity of pyrazine sorafenib analogues (2015) (0)
- Inhibition of autoimmune joint inflammation in mice by an antagonist of the SDF-1 chemokine receptor CXCR4 (2002) (0)
- Anti-HIV activity profile of a highly specific CD4 receptor down-modulating compound (2003) (0)
- heterocyclic compounds that bind to chemokine receptors and exhibit improved efficacy (2004) (0)
- A Novel Experimental Porcine Model to Assess the Impact of Differential Pulmonary Blood Flow on Primary Graft Dysfunction After Unilateral Lung Transplantation (2020) (0)
- Synthesis, Molecular Docking and Molecular Dynamics Simulation of 2-thioxothiazolidin-4-one derivatives against Gp41. (2020) (0)
- The candidate sulfonated microbicide, PRO 2000, has multiple mechanisms of antiviral action (2008) (0)
- Exposure of Raji / DC-SIGN cells to HIV-1 and subsequent cocultivation with CD 4 1 C 8166 cells in the presence of OAA and OPA (2014) (0)
- Potent and highly selective HIV-1 specific inhibition by a new series of alfa-anilino phenyl acetamide (alfa-APA) derivatives targeted at HIV-1 reverse transcriptase (1992) (0)
- Cell-Based Electrical Impedance Platform to Evaluate Zika Virus Inhibitors in Real Time. (2023) (0)
- 135 Safety Concerns for Cyanovirin as a Microbicidal Anti-HIV Agent (2007) (0)
- Synthesis of Unsymmetrical Cyclotriazadisulfonamide (CADA) Analogs as Human CD4 Down-Modulating Antivirals (2014) (0)
- Small molecule receptor inhibitors as a novel strategy for the inhibition of human immunodeficiency virus (HIV) infection (2006) (0)
- A second-generation of tryptophan-containing small molecules extremely potent against HIV and EV-A71 clinical isolates (2019) (0)
- Synthesis of electron-rich cyclotriazadisulfonamide (CADA) analogs as anti-HIV and human CD4 receptor down-modulating agents (2013) (0)
- In vitro evaluation of chloroquine as a microbicide candidate against HIV infection (2007) (0)
- Blockade of SIV and HIV infection with CADA, a novel entry inhibitor that specifically targets the cellular CD4 receptor (2005) (0)
- Anti-HIV activity and CD4 receptor down-modulating effect of cyclotriazadisulfonamide (CADA) structural analogs (2014) (0)
- Metal complexes of macrocyclic polyamines targeting the cellular HIV co-receptors, CXCR4 and CCR5 (2010) (0)
- The candidate microbicide CADA, an entry inhibitor that specifically targets the cellular CD4 receptor, prevents HIV and SIV infection of human and simian cells (2006) (0)
- Differential activity of candidate microbicide molecules against human immunodeficiency virus upon complement virus opsonization (2006) (0)
- Pharmaceutical performance of vaginal microbicide gels for the poorly water-soluble saquinavir in biorelevant media (2008) (0)
- Synthesis of novel N-acyl-β-d-glucopyranosylamines and ureas as potential lead cytostatic agents (2016) (0)
- Feglymycin, a unique natural bacterial peptide isolated from Streptomyces sp. DSM11171, potently inhibits HIV replication by interfering with the CD4/gp120 interaction (2012) (0)
- Establishment of a novel CCR5 and CXCR4 expressing CD4+ cell line which is suitable for high-throughput evaluation of HIV/coreceptor inhibitors (2004) (0)
- A stabilized CXCL9(74-103)-derived peptide selectively inhibits proliferation, adhesion and metastasis of tumor cells that express high levels of heparan sulfate. (2022) (0)
- Design, synthesis, and cytostatic activity of novel pyrazine sorafenib analogs (2016) (0)
- Naphthalenedisulfonic acid derivatives inhibit HIV-1-induced cytopathogenesis, syncytia formation and virus-cell binding by interaction with the viral envelope glycoprotein (1993) (0)
- Progress in the study of vertebrate-type neuropeptides in Locusta, Periplaneta and Sarcophaga (1986) (0)
- CXCL12/ALEXA FLUOR 647 : a novel, non-radioactive probe for flow cytometric evaluation of CXCR4 inhibitors (2004) (0)
- Synthesis of novel thioalkylated triazolothiazoles and their promising in-vitro antiviral activity (2023) (0)
- Corrigendum: Innate lymphoid cells are required to induce airway hyperreactivity in a murine neutrophilic asthma model (2022) (0)
- HIV-1 mutational pathways, resistance profile and potential side effects of cyanovirin (2006) (0)
- High affinity novel CXCR4 antagonists radiolabelled with copper-67 and gallium-68 for theragnostic applications (2022) (0)
- CADA, a specific down-modulator of the primary HIV receptor, acts as a small-molecule inhibitor of CD4 protein translocation into the ER (2012) (0)
- Brussel Lectin-Glycan Interaction Network-Based Identification of Host Receptors of Microbial Pathogenic (2016) (0)
- Human immunodeficiency virus gp120 as the primary target of action of AR177 (Zintevir) (1997) (0)
- Identification of Polyphenol Derivatives as Novel SARS-CoV-2 and DENV Non-Nucleoside RdRp Inhibitors (2022) (0)
- Mannose-specific lectins as novel microbicides against HIV (2003) (0)
- The lantibiotic, labyrinthopeptin A1, demonstrates a broad and unique anti-HIV activity profile (2015) (0)
- P.3.18 Early course of schizophrenic disorders;results from a Dutch epidemiological study (2005) (0)
- Cyclotriazadisulfonamide prevents HIV transmission and SIV infection by specifically targeting the cellular CD4 receptor (2008) (0)
- Cellular electrical impedance to profile SARS-CoV-2 fusion inhibitors and to assess the fusogenic potential of spike mutants (2022) (0)
- Modified proteins and their use for the control of viral infections (1992) (0)
- A novel class of HIV inhibitors that target the cellular CD4 receptor (2004) (0)
- Disulfide-containing macrolides that inhibit a late stage of the replicative cycle of human immunodeficiency virus (1997) (0)
- Cryo-EM structures of Doravirine and Rilpivirine with HIV-1 Reverse Transcriptase/DNA Aptamer – Nonnucleoside Inhibitor Resistance by E138K and M184I Mutations (2022) (0)
- A yellow fever–Zika chimeric virus vaccine candidate protects against Zika infection and congenital malformations in mice (2018) (0)
- HIV-1 resistance towards CADA-induced CD4 receptor-targeted inhibition is associated with increased sensitivity to neutralizing antibodies (2008) (0)
- Synthesis of novel CADA compounds and their anti-HIV and CD4 down-modulation activities (2004) (0)
- The role of DC-SIGN in HIV and dengue virus transmission and infection (2008) (0)
- Heterociclical compounds that join chemiokin receptors. (2000) (0)
- HIV-1 strains resistant to mannose- and N-acetylglucosamine-binding proteins show mutations at glycosylation sites of gp120 (2005) (0)
- Chemokine receptor antagonists as HIV entry inhibitors (2004) (0)
- Carbohydrate binding agents (CBA) cause the deletion of highly conserved glycosylation sites in the HIV-1 gp120 envelope (2005) (0)
- Cyclotriazadisulfonamide compounds prevent HIV infection of macrophages and dendritic cells by specifically targeting the cellular CD4 receptor (2009) (0)
- Consistent antiviral activity of carbohydrate-binding agents against the 4 different serotypes of dengue virus (2009) (0)
- Macrocyclic polyamines inhibit HIV infection by interacting with the cellular HIV co-receptors CXCR4 and CCR5 (2009) (0)
- The HIV entry inhibitor CADA selectively inhibits CD4 protein translocation: a novel approach for regulating the expression of the cellular HIV receptor (2010) (0)
- Design, Synthesis, Anti-Varicella-Zoster and Antimicrobial Activity of (Isoxazolidin-3-yl)Phosphonate Conjugates of N1-Functionalised Quinazoline-2,4-Diones (2022) (0)
- CADA compounds: potent CD4-targeted HIV inhibitors (2004) (0)
- Acyclic/Carbocyclic Guanosine Analogues as Anti‐Herpesvirus Agents (2001) (0)
- HIV-1 specific phenylacetamide derivatives: a novel class of reverse transcriptase inhibitors with potent and selective antiviral activity in vitro (1992) (0)
- The potential role of innate lymphoid cells in non-allergic neutrophilic asthma model (2022) (0)
- in 1 vitro Zika virus replication and delays disease progression in a robust mouse infection model 2 3 Running Title : Inhibition of Zika virus replication (2016) (0)
- Differential inhibition of R5-HIV-1 adsorption on epithelial HEC-1 cells, macrophages and dendritic cells, and HIV-1 transcytosis through polarized HEC-1 monolayer by mannose-specific plant lectins (2006) (0)
- Biological activity of novel primaquine-cinnamic acid conjugates of the amide type (2017) (0)
- Author response for "Pre‐protein signature for full susceptibility to the co‐translational translocation inhibitor cyclotriazadisulfonamide (CADA)" (2019) (0)
- Stimulation of the atypical chemokine receptor 3 (ACKR3) by a small-molecule agonist attenuates fibrosis in a preclinical liver but not lung injury model (2022) (0)
- Optimization of triazolo[4,5-d]pyrimidines towards human CC chemokine receptor 7 (CCR7) antagonists. (2023) (0)
- Decreased Ring Size in Cyclotriazadisulfonamide (CADA) Analogs with Preserved CD4 Down-Modulating and anti-HIV Activity (2014) (0)
- Introduction to the Special Issue dedicated to Prof. Erik De Clercq for reaching the Professor Emeritus status at the Katholieke Universiteit Leuven (2006) (0)
- Treatment of collagen-induced arthritis (CIA) in IFN-gammaR knock-out and wild-type mice with a specific CXCR4 inhibitor exposes different pathways in the pathogenesis of the disease (2003) (0)
- 2 A NOVEL IN VIVO MODEL FOR THE STUDY OF HIV-1 3 TRANSCRIPTION INHIBITORS : EVALUATION OF NEW 4 6-DESFLUOROQUINOLONE DERIVATIVES ( 6-DFQs ) 5 (2007) (0)
- Carbohydrate-Binding Agents (CBA) inhibit entry of the human immunodeficiency virus (HIV) into its target cells through binding on the glycans of the viral envelope gp120 (2006) (0)
- CD4 down-modulating activity of cyclotriazadisulfonamide (CADA) analogs correlates with their anti-HIV potency (2013) (0)
- Drug-induced inhibition of co-translational translocation of human CD4 into the endoplasmic reticulum (ER) (2013) (0)
- AMD3100, a potent and specific CXCR4 antagonist, inhibits autoimmune joint inflammation in mice (2001) (0)
- Dengue virus infection of human microvascular endothelial cells is inhibited by sulfated Escherichia coli K5 polysaccharide derivatives (2012) (0)
- Anti-HIV-1 activity and pharmaceutical availability in biorelevant media of gel-formulated saquinavir as a vaginal microbicide (2010) (0)
- Virulence Evolves In Vivo , Leading to Increased Immunodeficiency Virus with Nef Deleted Coreceptor Phenotype of Natural Human (2002) (0)
- Synthesis of novel N-acyl-β-d-glucopyranosylamines and ureas as potential lead cytostatic agents (2016) (0)
- Biological activity of novel primaquine-cinnamic acid conjugates of the acylsemicarbazide type (2017) (0)
- The candidate microbicide CADA prevents HIV transmission and SIV infection by specifically targeting the cellular CD4 receptor (2007) (0)
- Specific CD4 down-modulating compounds with potent anti-HIV and HHV-7 activity (2002) (0)
- Development of new cyclotriazadisulfonamide (CADA) analogs that inhibit HIV replication by down-modulation of the CD4 receptor (2013) (0)
- Cobinding to CCR5 Wide Target Compatibility and Synergic R4.0 with Different HIV-1 Blockers Reveals Combination of the CCL5-Derived Peptide (2014) (0)
- Effect of Molecular Symmetry on Potency in Novel Down-Modulators of the CD4 Receptor (2011) (0)
- Flow-cytometric evaluation of chemokine-induced Transwell cell migration (2003) (0)
- Griffithsin, a lectin isolated from Griffithsia sp. is endowed with potent and broad spectrum anti-HIV activity and has an outstanding safety profile (2012) (0)
- β-lactam analogs of oxetanocins – synthesis and biological activity (2022) (0)
- Griffithsin/CBA combinations demonstrate superior activity against HIV‐1, HIV‐2 and even against CBA‐resistant HIV‐1 strains (2011) (0)
- New 2-alkylthio-1-benzylimidazole-5-carboxylic acid derivatives targeting gp41: design, synthesis and in vitro anti-HIV activity evaluation. (2022) (0)
- Sugar-binding proteins potently inhibit HIV-1 infection of dendritic cells and dendritic cell-directed HIV-1 transfer (2005) (0)
This paper list is powered by the following services:
What Schools Are Affiliated With Dominique Schols?
Dominique Schols is affiliated with the following schools: