Domitilla Del Vecchio
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Why Is Domitilla Del Vecchio Influential?
(Suggest an Edit or Addition)According to Wikipedia, Domitilla Del Vecchio is an Italian control theorist, whose research connects control theory to systems biology, synthetic biology, synthetic biological circuits, and regenerative medicine. She has also studied self-organization in traffic control. She is a professor of mechanical engineering at the Massachusetts Institute of Technology and a member of the MIT Synthetic Biology Center.
Domitilla Del Vecchio's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Cooperative Collision Avoidance at Intersections: Algorithms and Experiments (2013) (268)
- Biomolecular Feedback Systems (2014) (191)
- Decomposition of human motion into dynamics-based primitives with application to drawing tasks (2003) (156)
- Least Restrictive Supervisors for Intersection Collision Avoidance: A Scheduling Approach (2015) (136)
- Duckietown: An open, inexpensive and flexible platform for autonomy education and research (2017) (136)
- Efficient algorithms for collision avoidance at intersections (2012) (131)
- Retroactivity Attenuation in Bio-Molecular Systems Based on Timescale Separation (2011) (81)
- A Contraction Theory Approach to Singularly Perturbed Systems (2011) (73)
- Modularity, context-dependence, and insulation in engineered biological circuits (2015) (72)
- Automated Vehicle-to-Vehicle Collision Avoidance at Intersections (2011) (62)
- Repressilators and promotilators: loop dynamics in synthetic gene networks (2005) (56)
- Future systems and control research in synthetic biology (2018) (52)
- Safety Control of Hidden Mode Hybrid Systems (2012) (51)
- Modular Composition of Gene Transcription Networks (2014) (47)
- Semiautonomous Multivehicle Safety (2011) (45)
- Robust multi-agent collision avoidance through scheduling (2013) (44)
- Supervisory control for intersection collision avoidance in the presence of uncontrolled vehicles (2014) (41)
- Computational Tools for the Safety Control of a Class of Piecewise Continuous Systems with Imperfect Information on a Partial Order (2011) (40)
- Partial order techniques for vehicle collision avoidance: Application to an autonomous roundabout test-bed (2009) (40)
- Limitations and trade-offs in gene expression due to competition for shared cellular resources (2014) (39)
- Programming Cells to Work for Us (2018) (37)
- A separation principle for a class of hybrid automata on a partial order (2009) (36)
- Supervisory control for collision avoidance in vehicular networks using discrete event abstractions (2013) (36)
- Design and Analysis of an Activator-Repressor Clock in E. Coli (2007) (35)
- Discrete state estimators for systems on a lattice (2006) (35)
- Boundary control for an industrial under-actuated tubular chemical reactor (2005) (35)
- Semi-autonomous Intersection Collision Avoidance through Job-shop Scheduling (2015) (33)
- Engineering principles in bio-molecular systems: From retroactivity to modularity (2009) (33)
- Adaptive Learning Control for Feedback Linearizable Systems (2003) (31)
- A control theoretic framework for modular analysis and design of biomolecular networks (2013) (30)
- Multi-modality in gene regulatory networks with slow promoter kinetics (2017) (27)
- Supervisory control of differentially flat systems based on abstraction (2011) (27)
- On the compromise between retroactivity attenuation and noise amplification in gene regulatory networks (2009) (27)
- Vision as a compensatory mechanism for disturbance rejection in upwind flight (2004) (25)
- Primitives for Human Motion: a Dynamical Approach (2002) (25)
- Control for Safety Specifications of Systems With Imperfect Information on a Partial Order (2014) (24)
- Computation of safety control for uncertain piecewise continuous systems on a partial order (2009) (23)
- Formal design of a provably safe robotic roundabout system (2010) (23)
- A method for determining the robustness of bio-molecular oscillator models (2009) (20)
- Retroactivity attenuation in transcriptional networks: Design and analysis of an insulation device (2008) (18)
- Supervisory control for collision avoidance in vehicular networks with imperfect measurements (2013) (18)
- Effective interaction graphs arising from resource limitations in gene networks (2015) (17)
- Observer-based control of block-triangular discrete time hybrid automata on a partial order† (2009) (17)
- Design of a lane departure driver-assist system under safety specifications (2016) (17)
- Experimental testing of a semi-autonomous multi-vehicle collision avoidance algorithm at an intersection testbed (2015) (17)
- Discrete State Estimators for a Class of Hybrid Systems on a Lattice (2004) (17)
- A Model for Resource Competition in CRISPR-Mediated Gene Repression (2018) (16)
- Mitigation of ribosome competition through distributed sRNA feedback (2016) (16)
- Stochastic analysis of retroactivity in transcriptional networks through singular perturbation (2012) (16)
- Control of hybrid automata with hidden modes: Translation to a perfect state information problem (2010) (16)
- A Partial Order Approach to Discrete Dynamic Feedback in a Class of Hybrid Systems (2007) (15)
- Synthetic Biology: A Systems Engineering Perspective (2008) (15)
- Continuous control of hybrid automata with imperfect mode information assuming separation between state estimation and control (2009) (15)
- Mitigation of resource competition in synthetic genetic circuits through feedback regulation (2014) (15)
- A systems theory with retroactivity: Application to transcriptional modules (2008) (14)
- Epigenetic cell memory: The gene’s inner chromatin modification circuit (2022) (13)
- Retroactivity to the input in complex gene transcription networks (2012) (12)
- Design of Driver-Assist Systems Under Probabilistic Safety Specifications Near Stop Signs (2015) (12)
- Repressilators and Promotilators : Loop Dynamics in Gene Regulatory Networks (2004) (12)
- Observability and local observer construction for unknown parameters in linearly and nonlinearly parameterized systems (2003) (11)
- Reduced linear noise approximation for biochemical reaction networks with time-scale separation: The stochastic tQSSA+ (2018) (11)
- Observation of guarded command programs (2003) (10)
- An adaptive learning control for feedback linearizable systems (2001) (10)
- Design of genetic circuits that are robust to resource competition (2021) (10)
- Segmentation of human motion into dynamics based primitives with application to drawing tasks (2003) (9)
- Design of insulating devices for in vitro synthetic circuits (2009) (9)
- Existence of discrete state estimators for hybrid systems on a lattice (2004) (9)
- Stochastic hybrid models for predicting the behavior of drivers facing the yellow-light-dilemma (2015) (9)
- Optimal design of phosphorylation-based insulation devices (2013) (9)
- Estimation for decentralized safety control under communication delay and measurement uncertainty (2015) (9)
- A contraction approach to input tracking via high gain feedback (2015) (9)
- Enforcing safety of cyberphysical systems using flatness and abstraction (2011) (9)
- Classification of human actions into dynamics based primitives with application to drawing tasks (2003) (8)
- Discrete state estimators for a class of nondeterministic hybrid systems on a lattice (2004) (8)
- Model reduction for a class of singularly perturbed stochastic differential equations (2015) (8)
- Dynamics and Control of Synthetic Bio-molecular Networks (2007) (8)
- Existence of Cascade Discrete-Continuous State Estimators for Systems on a Partial Order (2005) (7)
- Systems biology and control — A tutorial (2007) (7)
- Observers for a Class of Hybrid Systems on a Lattice (2004) (7)
- Analyzing and Exploiting the Effects of Protease Sharing in Genetic Circuits (2017) (7)
- The Effect of Compositional Context on Synthetic Gene Networks (2016) (7)
- Deterministic-Like Model Reduction for a Class of Multiscale Stochastic Differential Equations With Application to Biomolecular Systems (2019) (6)
- Integral action with time scale separation: A mechanism for modularity in biological systems (2014) (6)
- Safety in Semi-autonomous Multi-vehicle Systems: A Hybrid Control Approach (2011) (6)
- Robust moment closure method for the chemical master equation (2017) (6)
- The number of equilibrium points of perturbed nonlinear positive dynamical systems (2019) (6)
- Adaptive learning control for robot manipulators (2001) (5)
- Moment convergence in a class of singularly perturbed stochastic differential equations (2015) (5)
- Model order reduction for Linear Noise Approximation using time-scale separation (2016) (5)
- Safety control of piece-wise continuous order preserving systems (2011) (5)
- Modularity in signaling systems (2012) (5)
- Model reduction for a class of singularly perturbed stochastic differential equations: Fast variable approximation (2016) (5)
- Tuning an activator-repressor clock employing retroactivity (2011) (5)
- Multi-modality in gene regulatory networks with slow gene binding (2017) (5)
- Robust Supervisors for Intersection Collision Avoidance in the Presence of Uncontrolled Vehicles (2016) (4)
- Loading as a design parameter for genetic circuits (2016) (4)
- Non-Linear Prediction Horizon Time-Discretization for Model Predictive Control of Linear Sampled-Data Systems (2006) (4)
- Resource Sensor Design for Quantifying Resource Competition in Genetic Circuits (2018) (4)
- A burden-free gene overexpression system (2021) (3)
- Identification of decision rules in a human-controlled system: vehicles at a traffic intersection (2004) (3)
- Experimental Testing of Semi-autonomous Multi-vehicle Control for Collision Avoidance at Intersections (2015) (3)
- The impact of retroactivity on the input/output static characteristics of a signaling component (2010) (3)
- Stochastic analysis of genetic feedback controllers to reprogram a pluripotency gene regulatory network (2019) (3)
- Time-scale separation based design of biomolecular feedback controllers (2019) (3)
- Safety control of a class of stochastic order preserving systems with application to collision avoidance near stop signs (2015) (3)
- An N-stage cascade of phosphorylation cycles as an insulation device for synthetic biological circuits (2016) (3)
- Cascade estimators for systems on a partial order (2008) (3)
- Implementation And Simulation Of Phosphorylation-Based Insulator In Transcription-Translation Platform (2013) (3)
- What Have the Principles of Engineering Taught Us about Biological Systems? (2016) (3)
- Partial order techniques for the analysis and synthesis of hybrid and embedded systems (2007) (3)
- A Dynamical Model for the Low Efficiency of Induced Pluripotent Stem Cell Reprogramming (2015) (3)
- The Impact of Retroactivity on the Behavior of Biomolecular Systems (2011) (3)
- How slaves affect a master module in gene transcription networks (2013) (3)
- Evaluating the robustness of a biochemical network model (2007) (3)
- The “Power Network” of Genetic Circuits (2018) (3)
- Longitudinal Vehicle Dynamics Scaling and Implementation on a HIL Setup (2008) (3)
- Multi-time-scale biomolecular ‘quasi-integral’ controllers for set-point regulation and trajectory tracking (2018) (3)
- Retroactivity attenuation in signaling cascades (2011) (3)
- Observation of Hybrid Guarded Command Programs (2)
- The impact of retroactivity on information exchange in molecular communications (2020) (2)
- Complexity Management in the State Estimation of Multi‐Agent Systems (2007) (2)
- Stochastic multistationarity in a model of the hematopoietic stem cell differentiation network (2018) (2)
- An endoribonuclease-based incoherent feedforward loop for decoupling resource-limited genetic modules (2019) (2)
- Modules and Retroactivity : Theoretical Framework , Analysis , and Design (2007) (2)
- Genetic Circuit-Host Ribosome Transactions: Diffusion-Reaction Model (2019) (2)
- Reprogramming cooperative monotone dynamical systems * (2018) (2)
- State estimation in multi-agent decision and control systems (2005) (2)
- Development and experimental validation of a semi-autonomous cooperative active safety system (2011) (2)
- Discrete dynamic feedback for a class of hybrid systems on a lattice (2006) (2)
- Substrate-induced modulation of signal transduction networks (2011) (2)
- Observer-based control for block-triangular hybrid automata (2007) (2)
- Hitting time behavior for the solution of a stochastic differential equation (2016) (2)
- Retroactivity attenuation through signal transduction cascades (2014) (2)
- The effect of retroactivity on the transfer function of a phosphorylation system (2010) (2)
- Modular Composition of Gene Transcription Networks Citation (2014) (2)
- Chapter 1. Introductory Concepts (2014) (1)
- Reprogramming Cooperative Monotone Dynamical Systems Behaviors (2018) (1)
- Deterministic model derivation and model reduction of an activator-repressor genetic oscillator (2016) (1)
- How retroactivity impacts the robustness of genetic networks (2015) (1)
- Approximation of the Chemical Master Equation using conditional moment closure and time-scale separation (2019) (1)
- Control of Hidden Mode Hybrid Systems: Algorithm termination (2011) (1)
- Trade-offs between retroactivity and noise in connected transcriptional components (2014) (1)
- Reprogramming Multistable Monotone Systems With Application to Cell Fate Control (2020) (1)
- Deterministic-like model reduction for a class of multi-scale stochastic differential equations with application to biomolecular systems (Extended Version) (2017) (1)
- Retroactivity to the Input and Thevenin ’ s Theorem for Complex Gene Transcription Networks (2012) (1)
- PRIMITIVES FOR HUMANMOTION : A DYNAMICAL APPROACH (2011) (1)
- Automatic Quantifications of Dynamics of Genetic Circuits in a Single Cell in Chemostat (2015) (1)
- Stochasticity is necessary for multiple attractors in a class of differentiation networks (2018) (1)
- Evaluation of closed-loop performance of an estimation strategy for decentralized safety controller under communication delay and measurement uncertainty (2015) (1)
- Interconnecting Components 7 . 1 Input / Output Modeling and the Modularity Assumption (2010) (1)
- A Control Theoretic Framework for the Analysis and Design of Biological Networks (2013) (1)
- Lane Departure Assist : A Formal Approach (2015) (1)
- Resource Creating Single-Copy Gen etic Circuits Graphical (2016) (1)
- Signaling architectures that transmit unidirectional information (2016) (1)
- Model order reduction for Linear Noise Approximation using time-scale separation (Extended Version) (2016) (1)
- What Is the Trait d’Union between Retroactivity and Molecular Communication Performance Limits? (2021) (1)
- Order Preserving Properties of Vehicle Dynamics with Respect to the Driver's Input (2014) (1)
- Design of a lane departure driver-assist system under safety specications: Theorems and Proofs (2016) (1)
- A partial order approach for low complexity control of block triangular hybrid automata (2007) (1)
- Stochastic Stability Properties of a Singularly Perturbed Chemical Langevin Equation (2014) (1)
- CASCADE DISCRETE-CONTINUOUS STATE ESTIMATORS FOR A CLASS OF MONOTONE SYSTEMS (2005) (1)
- The Enhanced Finite State Projection algorithm, using conditional moment closure and time-scale separation (2020) (0)
- Invited Tutorial Sessions (2007) (0)
- Simplexes characterize the coupling in gene expression due to competition for rnap and ribosomes (2015) (0)
- Controller design under safety specifications for a class of bounded hybrid automata (2016) (0)
- Chapter 2. Dynamic Modeling of Core Processes (2014) (0)
- Identifiability of linear noise approximation models of chemical reaction networks from stationary distributions (2022) (0)
- Impact of Retroactivity on Transcriptional Components (2013) (0)
- Emergent interactions due to resource competition in CRISPR-mediated genetic activation circuits* (2022) (0)
- Chapter 6. Interconnecting Components (2014) (0)
- Biophysical Constraints A rising from Compositional Context in Synthetic Gene Networks Graphical (2017) (0)
- Modularity in Signaling Systems 2 (2012) (0)
- Differential Equation Model for the Population-Level Dynamics of a Toggle Switch with Growth-Feedback (2022) (0)
- Understanding and Mitigating the Effects of Limited Transcriptional Resources in Mammalian Cells (2017) (0)
- THE ROLE OF RIBOSOME AUTOCATALYSIS AND FEEDBACK IN RESOURCE COMPETITION (2015) (0)
- NSF Workshop: Systems and Control Theory for Synthetic Biology (2021) (0)
- Design of a long-term memory genetic toggle switch inspired by chromatin modification circuits (2022) (0)
- Chapter 7. Design Tradeoffs (2014) (0)
- Synthetic Biology (2015) (0)
- Modularity in Complex Gene Transcription Networks (2013) (0)
- Supplementary Information to “ Multimodality in gene regulatory networks with slow promoter kinetics ” (2019) (0)
- Reprogramming cell fate : Systemic failures and their mitigation through feedback control (2016) (0)
- An Introduction to Control of Synthetic Biomolecular Systems (2007) (0)
- Analytical and computational study of the stochastic behavior of a chromatin modification circuit * (2022) (0)
- Population-Level Model of the Transient Dynamics of a Toggle Switch with Growth Feedback (2022) (0)
- Engineering insulation from retroactivity of the frequency response of covalent modification cycles (2011) (0)
- Trade-offs in Robustness to Perturbations of Bacterial Population Controllers * (2020) (0)
- A Control Theory Approach to Engineering Biomolecular Networks (2013) (0)
- Chapter 5. Biological Circuit Components (2014) (0)
- Development of safety control for hidden mode hybrid systems and verification in the multi-vehicle lab (2011) (0)
- Quantitative Analysis, Design, and Fabrication of Biosensing and Bioprocessing Devices in Living Cells (2015) (0)
- People in control - Traffic and Weather (2007) (0)
- Identifiability of Chemical Reaction Networks with Intrinsic and Extrinsic Noise from Stationary Distributions (2021) (0)
- Chapter 1 THE IMPACT OF RETROACTIVITY ON THE BEHAVIOR OF BIOMOLECULAR SYSTEMS A Review of Recent Results (2010) (0)
- Competition for Shared Resources in the Cellular Chassis: Impact on Synthetic Circuits (2013) (0)
- Chapter 4. Stochastic Modeling and Analysis (2014) (0)
- Biophysical Constraints Arising From Relative Gene OrientaCompositional Contexttion in Synthetic Gene Networks (2017) (0)
- Observability-based Motion Planning (2006) (0)
- Design of an insulation device using phosphotransfer systems (2010) (0)
- Chapter 3. Analysis of Dynamic Behavior (2014) (0)
- Context dependence of biological circuits: Predictive models and engineering solutions (2020) (0)
- Spatial heterogeneity tunes the behavior of bacterial genetic circuits (2019) (0)
- Adaptive control of feedback linearizable systems by orthogonal approximation functions (2001) (0)
- Computation of Safety Control for Hybrid System with Applications to Intersection Collision Avoidance System (2016) (0)
- 1 Tuning Genetic Clocks Employing DNA Binding Sites (2012) (0)
- Model reduction and stochastic analysis of the histone modification circuit (2022) (0)
- Spatial Heterogeneity in Bacterial Cells (2020) (0)
- Design of safety distributed control under bounded time-varying communication delay (2014) (0)
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Domitilla Del Vecchio is affiliated with the following schools:
