Don Mason
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British immunologist
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Don Mason biology Degrees
Biology
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Immunology
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Biology
Don Mason 's Degrees
- PhD Immunology University of Oxford
- Bachelors Biochemistry University of Oxford
Why Is Don Mason Influential?
(Suggest an Edit or Addition)According to Wikipedia, Donald W. Mason was a British immunologist and professor of immunology in the MRC Cellular Immunology Unit at the Sir William Dunn School of Pathology at the University of Oxford. Professor Mason is best known for his work on regulatory T cells and their role in preventing autoimmunity. His distinction was recognised by his election in 2017 to honorary life membership of the British Society for Immunology.
Don Mason 's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- A very high level of crossreactivity is an essential feature of the T-cell receptor. (1998) (996)
- Two subsets of rat T lymphocytes defined with monoclonal antibodies (1980) (656)
- Macrophage heterogeneity in the rat as delineated by two monoclonal antibodies MRC OX-41 and MRC OX-42, the latter recognizing complement receptor type 3. (1986) (622)
- Human CD4+CD25+ thymocytes and peripheral T cells have immune suppressive activity in vitro (2001) (558)
- The kinetics of antibody binding to membrane antigens in solution and at the cell surface. (1980) (538)
- Glucocorticoids promote a TH2 cytokine response by CD4+ T cells in vitro. (1996) (521)
- Evidence that the T cell repertoire of normal rats contains cells with the potential to cause diabetes. Characterization of the CD4+ T cell subset that inhibits this autoimmune potential (1993) (494)
- Control of immune pathology by regulatory T cells. (1998) (424)
- OX-22high CD4+ T cells induce wasting disease with multiple organ pathology: prevention by the OX-22low subset [published erratum appears in J Exp Med 1991 Apr 1;173(4):1037] (1990) (400)
- CD25 Is a Marker for CD4+ Thymocytes That Prevent Autoimmune Diabetes in Rats, But Peripheral T Cells with This Function Are Found in Both CD25+ and CD25− Subpopulations1 (2000) (377)
- Spontaneous recovery of rats from experimental allergic encephalomyelitis is dependent on regulation of the immune system by endogenous adrenal corticosteroids (1989) (359)
- Peripheral Autoantigen Induces Regulatory T Cells that Prevent Autoimmunity (1999) (324)
- Functions of Rat T‐Lymphocyte Subsets Isolated by Means of Monoclonal Antibodies (1983) (310)
- Regulatory T Cells in the Control of Autoimmunity: the Essential Role of Transforming Growth Factor β and Interleukin 4 in the Prevention of Autoimmune Thyroiditis in Rats by Peripheral CD4+CD45RC− Cells and CD4+CD8− Thymocytes (1999) (297)
- The fate of allogeneic and xenogeneic neuronal tissue transplanted into the third ventricle of rodents (1986) (288)
- Graft-versus-host disease induces expression of Ia antigen in rat epidermal cells and gut epithelium (1981) (273)
- T-lymphocyte heterogeneity in the rat: separation of functional subpopulations using a monoclonal antibody (1978) (259)
- The third function of the thymus. (2000) (245)
- MRC OX-22, a monoclonal antibody that labels a new subset of T lymphocytes and reacts with the high molecular weight form of the leukocyte-common antigen (1983) (244)
- Genetic variation in the stress response: susceptibility to experimental allergic encephalomyelitis and implications for human inflammatory disease. (1991) (241)
- Experimental allergic encephalomyelitis: successful treatment in vivo with a monoclonal antibody that recognizes T helper cells. (1984) (229)
- Molecular cloning of rat interleukin 4 cDNA and analysis of the cytokine repertoire of subsets of CD4+ T cells (1991) (225)
- The role of the neuroendocrine system in determining genetic susceptibility to experimental allergic encephalomyelitis in the rat. (1990) (218)
- Induction of Ia antigen in rat epidermal cells and gut epithelium by immunological stimuli (1982) (212)
- Human cell-adhesion molecule CD2 binds CD58 (LFA-3) with a very low affinity and an extremely fast dissociation rate but does not bind CD48 or CD59. (1994) (210)
- T cells that help B cell responses to soluble antigen are distinguishable from those producing interleukin 2 on mitogenic or allogeneic stimulation (1986) (208)
- Effector mechanisms in allograft rejection. (1986) (204)
- Subsets of CD4+ T Cells and their Roles in the Induction and Prevention of Autoimmunity (1991) (194)
- The roles of host and donor cells in the rejection of skin allografts by T cell‐deprived rats injected with syngeneic T cells (1982) (190)
- Experimental allergic encephalomyelitis in the absence of a classical delayed-type hypersensitivity reaction. Severe paralytic disease correlates with the presence of interleukin 2 receptor-positive cells infiltrating the central nervous system (1987) (169)
- Intrathymic expression of genes involved in organ specific autoimmune disease. (1998) (161)
- Prevention of experimental allergic encephalomyelitis in rats by targeting autoantigen to B cells: evidence that the protective mechanism depends on changes in the cytokine response and migratory properties of the autoantigen-specific T cells (1995) (155)
- The Thymus Contains a High Frequency of Cells that Prevent Autoimmune Diabetes on Transfer into Prediabetic Recipients (1996) (155)
- Signaling lymphocytic activation molecule (CDw150) is homophilic but self-associates with very low affinity. (2000) (154)
- The Physiological Role of Regulatory T Cells in the Prevention of Autoimmunity: the Function of the Thymus in the Generation of the Regulatory T Cell Subset (1996) (142)
- Phenotypic and functional heterogeneity of CD4+ T cells. (1988) (131)
- The rat mixed lymphocyte reaction: roles of a dendritic cell in intestinal lymph and T-cell subsets defined by monoclonal antibodies. (1981) (117)
- The MRC OX-22- CD4+ T cells that help B cells in secondary immune responses derive from naive precursors with the MRC OX-22+ CD4+ phenotype (1989) (114)
- Selective killing of malignant cells in a leukaemic rat bone marrow using an antibody–ricin conjugate (1982) (101)
- Targeting autoantigen to B cells prevents the induction of a cell- mediated autoimmune disease in rats (1992) (94)
- Physical association of the cytoplasmic domain of CD2 with the tyrosine kinases p56lck and p59fyn (1993) (93)
- Inhibition of mixed lymphocyte response by monoclonal antibody specific for a rat T lymphocyte subset (1979) (92)
- Activation of CD4+ T cells in the presence of a nondepleting monoclonal antibody to CD4 induces a Th2-type response in vitro (1995) (88)
- Memory CD4+ T cells in man form two distinct subpopulations, defined by their expression of isoforms of the leucocyte common antigen, CD45. (1990) (87)
- MRC OX-43: a monoclonal antibody which reacts with all vascular endothelium in the rat except that of brain capillaries. (1986) (84)
- Autoregulation of autoantibody synthesis in mercuric chloride nephritis in the Brown Norway rat I. A role for T suppressor cells (1984) (76)
- SUBSETS OF T CELLS IN THE RAT MEDIATING LETHAL GRAFT‐VERSUS-HOST DISEASE (1981) (76)
- MRC OX-52: a rat T-cell antigen. (1986) (71)
- In rat bone marrow Thy‐1 antigen is present on cells with membrane immunoglobulin and on precursors of peripheral B lymphocytes (1977) (70)
- Subsets of rat CD4+ T cells defined by their differential expression of variants of the CD45 antigen: developmental relationships and in vitro and in vivo functions. (1990) (60)
- Induction of Ia antigens on murine epidermal cells during the rejection of skin allografts. (1983) (58)
- Mechanisms of Allograft Rejection: The Roles of Cytotoxic T‐Cells and Delayed‐Type Hypersensitivity (1984) (57)
- Evidence that rat renal allografts are rejected by cytotoxic T cells and not by nonspecific effectors. (1985) (55)
- CD4+CD8− thymocytes that express L‐selectin protect rats from diabetes upon adoptive transfer (1996) (50)
- The mechanism of inhibition of experimental allergic encephalomyelitis in the rat by monoclonal antibody against CD4 (1986) (49)
- The class of surface immunoglobulin on cells carrying IgG memory in rat thoracic duct lymph: the size of the subpopulation mediating IgG memory (1976) (47)
- Monoclonal Antibodies That Define T-Lymphocyte Subsets in the Rat (1980) (46)
- Some quantitative aspects of T‐cell repertoire selection: the requirement for regulatory T cells (2001) (46)
- Phenotypic characterization of regulatory CD4+CD25+ T cells in rats. (2004) (45)
- Immunology: Graft rejection and Ia antigens — paradox resolved? (1983) (36)
- Induction of resistance to active experimental allergic encephalomyelitis by myelin basic protein‐specific Th2 cell lines generated in the presence of glucocorticoids and IL‐4 (2000) (36)
- The role of serum factors in the suppression of experimental allergic encephalomyelitis: evidence for immunoregulation by antibody to the encephalitogenic peptide. (1990) (35)
- T-cell subsets in autoimmunity. (1992) (31)
- Phenotypic analysis of peripheral CD4+ CD8+ T cells in the rat (2000) (30)
- Allelic exclusion of α chains in TCRs (1994) (28)
- The role of B cells in the programming of T cells for IL-4 synthesis (1996) (27)
- The requirement for C3 receptors on the precursors of 19S and 7S antibody-forming cells (1976) (27)
- Tissue distribution and quantitation of la‐like antigens in the rat (1978) (26)
- INHIBITION OF THE ACCUMULATION, IN RAT KIDNEY ALLOGRAFTS, OF SPECIFIC—BUT NOT NONSPECIFIC—CYTOTOXIC CELLS BY CYCLOSPORINE (1984) (26)
- Glucocorticoids induce the expression of CD8 alpha chains on concanavalin A-activated rat CD4+ T cells: induction is inhibited by rat recombinant interleukin 4 (1992) (26)
- The role of subsets of CD4+ T cells in autoimmunity. (1995) (25)
- CD2 physically associates with CD5 in rat T lymphocytes with the involvement of both extracellular and intracellular domains (2002) (24)
- Studies on the refractoriness to reinduction of experimental allergic encephalomyelitis in Lewis rats that have recovered from one episode of the disease (1990) (24)
- Graft rejection and Ia antigens--paradox resolved? (1983) (23)
- Peptides derived from murine insulin are diabetogenic in both rats and mice, but the disease-inducing epitopes are different: evidence against a common environmental cross-reactivity in the pathogenicity of type 1 diabetes. (1999) (22)
- Constitutive and inducible expression of Ia antigens. (1984) (22)
- Homeostatic mechanisms in the control of autoimmunity. (1997) (22)
- CD8α is an activation marker for a subset of peripheral CD4 T cells (2004) (22)
- Evaluation of resistance to staphylococcal enterotoxin B: naturally acquired antibodies of man and monkey. (1971) (20)
- Experimental allergic encephalomyelitis in the rat (1996) (20)
- Lineage relationships and functions of CD4+ T-cell subsets in the rat. (1991) (20)
- Recirculatory and Sessile CD4+ T Lymphocytes Differ on CD45RC Expression1 (2000) (19)
- AND GUT EPITHELIUM BY IMMUNOLOGICAL STIMULI (1982) (19)
- The role of lymphocyte subpopulations in the transfer of rat EAE (1986) (18)
- Subsets of CD4+ T cells defined by their expression of different isoforms of the leucocyte-common antigen, CD45. (1992) (18)
- Subpopulations − and CD 25 + Are Found in Both CD 25 But Peripheral T Cells with This Function That Prevent Autoimmune Diabetes in Rats , Thymocytes + CD 25 Is a Marker for CD 4 (2000) (17)
- Characterisation of thymus-derived regulatory T cells that protect against organ-specific autoimmune disease. (2001) (17)
- The role of the thymus in the control of autoimmunity. (1996) (16)
- The autonomy of CD8+ T cells in vitro and in vivo. (1988) (14)
- Sequence of rat interleukin 2 and anomalous binding of a mouse interleukin 2 cDNA probe to rat MHC class II-associated invariant chain mRNA (2006) (14)
- T-cell-mediated control of autoimmunity (2001) (13)
- Role of thymus-derived and thymus-independent cells in murine skin allograft rejection. (1982) (12)
- The roles of T cell subpopulations in allograft rejection. (1988) (12)
- Rat interleukin-4 assays. (1998) (12)
- CD8 alpha is an activation marker for a subset of peripheral CD4 T cells. (2004) (11)
- Effects of cytokines and glucocorticoids on endogenous class II MHC antigen expression by activated rat CD4+ T cells. Mature CD4+ CD8- thymocytes are phenotypically heterogeneous on activation. (1996) (11)
- Loss of encephalitogenicity of a myelin basic protein-specific T cell line is associated with a phenotypic change but not with alteration in production of interleukin-2, γ-interferon or tumour necrosis factor (1990) (11)
- Sequence of a rat MHC class II-associated invariant chain cDNA clone containing a 64 amino acid thyroglobulin-like domain. (1989) (11)
- The tolerization of rat thymocytes to xenogeneic erythrocytes: kinetics of induction and recovery (1981) (11)
- Elimination of leukaemic cells from rodent bone marrow in vitro with antibody-ricin conjugates: Implications for autologous marrow transplantation in man (1982) (10)
- An improved autoradiographic technique for the detection of antibody-forming cells. (1976) (10)
- Demonstration of the stability of the membrane phenotype of T helper cells after priming and boosting with a hapten‐carrier conjugate (1983) (10)
- The Possible Role of Class II Major Histocompatibility Complex Antigens in Self Tolerance (1985) (9)
- Subsets of CD4+ T cells and their roles in autoimmunity. (1993) (7)
- Subpopulations of T cells in the rat that mediate graft-versus-host reactions and lethal graft-versus-host disease. (1982) (6)
- The roles of the hypothalamus and the gastrointestinal tract in the prevention of inflammatory autoimmune disease (1994) (6)
- A monoclonal antibody which can distinguish between the two isotypes of human C4. (1987) (5)
- Allelic exclusion of alpha chains in TCRs. (1994) (5)
- Response of irradiated mice to live-virus (TC-83) immunization (1975) (5)
- Subpopulations of T lymphocytes. (1987) (5)
- Monoclonal antibody therapy: "model" experiments with toxin-conjugated antibodies in mice and rats. (1983) (4)
- Deaggregated homologous immunoglobulin‐peptide conjugates induce peptide‐specific T cell nonresponsiveness in vivo (1998) (4)
- Induction of Autoimmune Disease by Depletion of Regulatory T Cells (1999) (4)
- Evidence for an Immunosuppressive Autoantibody in Experimental Allergic Encephalomyelitis (1988) (4)
- Subsets of rat CD4+ T cells express different variants of the leukocyte-common antigen: functions and developmental relationships of the subsets. (1989) (3)
- Immunoregulation in experimental allergic encephelomyelitis (EAE) by mechanisms other than suppressor T-cells (1987) (3)
- A monoclonal antibody to C1q which appears to interact with C½C½s2‐binding site (1988) (3)
- T-cell subsets in experimental allergic encephalomyelitis: interactions between the immune and neuroendocrine systems in the regulation of their activity. (1992) (3)
- The refractory phase of experimental allergic encephalomyelitis in the Lewis rat is antigen specific in its induction but not in its effect (1991) (2)
- CORRELATION BETWEEN AN ABERRANT SEROLOGICAL RESPONSE TO TRANSPLANTATION ANTIGENS AND RENAL ALLOGRAFT ENHANCEMENT IN ALLOGENEIC RECIPIENTS (1978) (2)
- Role of CD4+CD8- thymocytes in the prevention of autoimmune diabetes. (1997) (2)
- Failure to demonstrate allotype-specific helper cells for antibody production in the rat (1977) (2)
- Subpopulations of B lymphocytes and the carriage of immunological memory. (1976) (2)
- A spleen‐thymus interaction is involved in the tolerization of thymocytes to xenogeneic erythrocytes (1983) (1)
- Class II major histocompatibility complex antigens expressed on blood vascular endothelial cells. (1983) (1)
- No observed role for CD8+ (suppressor/cytotoxic) T lymphocytes in the immunoregulation of EAE in the rat (1987) (1)
- OX2210 CD4+ T Cells Induce Wasting Disease with Multiple Organ Pathology: Prevention by the OX-221 ow Subset (2003) (0)
- Mechanism of allograft rejection mode of action of cyclosporine and passive enhancement (1985) (0)
- Experimental allergic encephalo- myelitis in the rat (1996) (0)
- EAE in the rat in the absence of a classic delayed-type hypersensitivity reaction: exploring the role of cytotoxic CD4+ T cells and vascular damage in pathogenesis (1987) (0)
- Corticosterone and the hypothalamic-pituitary adrenal (HPA) axis in autoimmune diseases (1997) (0)
- 35TH FORUM IN IMMUNOLOGY - DISCUSSION (1991) (0)
- Lymphocytes Differ on CD45RC Expression T + Recirculatory and Sessile CD4 (0)
- Regulatory T Cells in the Control of Autoimmunity: the Essential Role of Transforming Growth Factor and Interleukin 4 in the Prevention of Autoimmune Thyroiditis in Rats by Peripheral CD4 CD45RC Cells and CD4 CD8 (cid:50) Thymocytes (1999) (0)
- Immunoregulation of experimental autoimmune disease in the rat (1997) (0)
- Activated rat T cells synthesize class II MHC antigens Expression is effected by cytokines and glucocorticoids (1995) (0)
- Tissue Distribution of Cells Binding MRC 0 X22 Monoclonal Antibody Flow Cytofluorograph Analysis (2003) (0)
- Rheumatic Diseases: T lymphocyte subsets in relation to autoimmune disease (1999) (0)
- ALLERGIC ENCEPHALOMYELITIS IN THE ABSENCE OF A CLASSICAL DELAYED-TYPE HYPERSENSITIVITY REACTION Severe Paralytic Disease Correlates with the Presence of Interleukin 2 Receptor-positive Cells Infiltrating the Central Nervous System (2003) (0)
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