Donald M. Bers
#63,283
Most Influential Person Now
American cardiologist
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Donald M. Bersmedical Degrees
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Cardiology
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Donald M. Bers's Degrees
- Masters Medicine University of California, San Francisco
- PhD Physiology University of California, San Francisco
Why Is Donald M. Bers Influential?
(Suggest an Edit or Addition)Donald M. Bers's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Cardiac excitation–contraction coupling (2002) (4255)
- Excitation-Contraction Coupling and Cardiac Contractile Force (1991) (1714)
- Calcium cycling and signaling in cardiac myocytes. (2008) (1223)
- Arrhythmogenesis and Contractile Dysfunction in Heart Failure: Roles of Sodium-Calcium Exchange, Inward Rectifier Potassium Current, and Residual &bgr;-Adrenergic Responsiveness (2001) (779)
- Relaxation in rabbit and rat cardiac cells: species‐dependent differences in cellular mechanisms. (1994) (746)
- Ca2+/Calmodulin–Dependent Protein Kinase Modulates Cardiac Ryanodine Receptor Phosphorylation and Sarcoplasmic Reticulum Ca2+ Leak in Heart Failure (2005) (695)
- Calcium fluxes involved in control of cardiac myocyte contraction. (2000) (597)
- A practical guide to the preparation of Ca2+ buffers. (1994) (595)
- Abnormal calcium handling properties underlie familial hypertrophic cardiomyopathy pathology in patient-specific induced pluripotent stem cells. (2013) (566)
- Fractional SR Ca release is regulated by trigger Ca and SR Ca content in cardiac myocytes. (1995) (565)
- A mathematical treatment of integrated Ca dynamics within the ventricular myocyte. (2004) (540)
- Ca2+/calmodulin-dependent protein kinase II regulates cardiac Na+ channels. (2006) (499)
- Cellular Basis of Abnormal Calcium Transients of Failing Human Ventricular Myocytes (2003) (490)
- The &dgr;C Isoform of CaMKII Is Activated in Cardiac Hypertrophy and Induces Dilated Cardiomyopathy and Heart Failure (2003) (479)
- Drug Screening Using a Library of Human Induced Pluripotent Stem Cell–Derived Cardiomyocytes Reveals Disease-Specific Patterns of Cardiotoxicity (2013) (473)
- Local InsP3-dependent perinuclear Ca2+ signaling in cardiac myocyte excitation-transcription coupling. (2006) (468)
- Diabetic Hyperglycemia activates CaMKII and Arrhythmias by O linked Glycosylation (2013) (449)
- Transgenic CaMKII&dgr;C Overexpression Uniquely Alters Cardiac Myocyte Ca2+ Handling: Reduced SR Ca2+ Load and Activated SR Ca2+ Release (2003) (444)
- Upregulation of Na(+)/Ca(2+) exchanger expression and function in an arrhythmogenic rabbit model of heart failure. (1999) (413)
- CaMKII in myocardial hypertrophy and heart failure. (2011) (410)
- Ca2+ handling and sarcoplasmic reticulum Ca2+ content in isolated failing and nonfailing human myocardium. (1999) (408)
- A novel computational model of the human ventricular action potential and Ca transient. (2010) (401)
- Cellular basis of triggered arrhythmias in heart failure. (2004) (365)
- Surface:volume relationship in cardiac myocytes studied with confocal microscopy and membrane capacitance measurements: species-dependence and developmental effects. (1996) (350)
- Requirement for Ca2+/calmodulin-dependent kinase II in the transition from pressure overload-induced cardiac hypertrophy to heart failure in mice. (2009) (349)
- Altered cardiac myocyte Ca regulation in heart failure. (2006) (345)
- Elevated Sarcoplasmic Reticulum Ca2+ Leak in Intact Ventricular Myocytes From Rabbits in Heart Failure (2003) (340)
- Human Atrial Action Potential and Ca2+ Model: Sinus Rhythm and Chronic Atrial Fibrillation (2011) (325)
- Intracellular Na+ Concentration Is Elevated in Heart Failure But Na/K Pump Function Is Unchanged (2002) (324)
- Sarcoplasmic reticulum Ca(2+) release causes myocyte depolarization. Underlying mechanism and threshold for triggered action potentials. (2000) (319)
- Approximate model of cooperative activation and crossbridge cycling in cardiac muscle using ordinary differential equations. (2008) (319)
- Role of Ca2+/calmodulin-dependent protein kinase (CaMK) in excitation-contraction coupling in the heart. (2007) (316)
- Macromolecular complexes regulating cardiac ryanodine receptor function. (2004) (313)
- Intracellular Na+ regulation in cardiac myocytes. (2003) (309)
- Calcium, calmodulin, and calcium-calmodulin kinase II: heartbeat to heartbeat and beyond. (2002) (307)
- Hypercontractile Female Hearts Exhibit Increased S-Nitrosylation of the L-Type Ca2+ Channel &agr;1 Subunit and Reduced Ischemia/Reperfusion Injury (2006) (299)
- Potentiation of fractional sarcoplasmic reticulum calcium release by total and free intra-sarcoplasmic reticulum calcium concentration. (2000) (297)
- SparkMaster: automated calcium spark analysis with ImageJ. (2007) (297)
- Oxygen-bridged Dinuclear Ruthenium Amine Complex Specifically Inhibits Ca2+ Uptake into Mitochondria in Vitroand in Situ in Single Cardiac Myocytes* (1998) (295)
- Quantitative Assessment of the SR Ca2+ Leak-Load Relationship (2002) (295)
- Ryanodine Receptor Phosphorylation by Calcium/Calmodulin-Dependent Protein Kinase II Promotes Life-Threatening Ventricular Arrhythmias in Mice With Heart Failure (2010) (278)
- Sarcoplasmic reticulum Ca2+ and heart failure: roles of diastolic leak and Ca2+ transport. (2003) (277)
- Screening Drug-Induced Arrhythmia Using Human Induced Pluripotent Stem Cell–Derived Cardiomyocytes and Low-Impedance Microelectrode Arrays (2013) (277)
- Ca influx and sarcoplasmic reticulum Ca release in cardiac muscle activation during postrest recovery. (1985) (276)
- Protein Kinase A Phosphorylation of the Ryanodine Receptor Does Not Affect Calcium Sparks in Mouse Ventricular Myocytes (2002) (276)
- β-Adrenergic Enhancement of Sarcoplasmic Reticulum Calcium Leak in Cardiac Myocytes Is Mediated by Calcium/Calmodulin-Dependent Protein Kinase (2007) (275)
- Reactive Oxygen Species–Activated Ca/Calmodulin Kinase II&dgr; Is Required for Late INa Augmentation Leading to Cellular Na and Ca Overload (2011) (271)
- A practical guide to the preparation of Ca(2+) buffers. (2010) (269)
- Cardiac sarcoplasmic reticulum calcium leak: basis and roles in cardiac dysfunction. (2014) (269)
- The Mitochondrial Calcium Uniporter Selectively Matches Metabolic Output to Acute Contractile Stress in the Heart. (2015) (268)
- A simple method for the accurate determination of free [Ca] in Ca-EGTA solutions. (1982) (265)
- Ca2+/Calmodulin-Dependent Protein Kinase II Phosphorylation of Ryanodine Receptor Does Affect Calcium Sparks in Mouse Ventricular Myocytes (2006) (257)
- Mitochondrial and sarcolemmal Ca2+ transport reduce [Ca2+]i during caffeine contractures in rabbit cardiac myocytes. (1992) (253)
- Rat vs. rabbit ventricle: Ca flux and intracellular Na assessed by ion-selective microelectrodes. (1989) (248)
- Effects of [Ca2+]i, SR Ca2+ load, and rest on Ca2+ spark frequency in ventricular myocytes. (1997) (245)
- Phosphorylation of phospholamban and troponin I in beta-adrenergic-induced acceleration of cardiac relaxation. (2000) (235)
- Ca channels in cardiac myocytes: structure and function in Ca influx and intracellular Ca release. (1999) (234)
- Cardiac myocyte calcium transport in phospholamban knockout mouse: relaxation and endogenous CaMKII effects. (1998) (234)
- The effect of temperature and ionic strength on the apparent Ca-affinity of EGTA and the analogous Ca-chelators BAPTA and dibromo-BAPTA. (1987) (224)
- Ratio of ryanodine to dihydropyridine receptors in cardiac and skeletal muscle and implications for E-C coupling. (1993) (224)
- Ca-dependent facilitation of cardiac Ca current is due to Ca-calmodulin-dependent protein kinase. (1994) (216)
- LabHEART: an interactive computer model of rabbit ventricular myocyte ion channels and Ca transport. (2001) (214)
- Ca2+ Scraps: Local Depletions of Free [Ca2+] in Cardiac Sarcoplasmic Reticulum During Contractions Leave Substantial Ca2+ Reserve (2003) (211)
- CaMKIIδ Isoforms Differentially Affect Calcium Handling but Similarly Regulate HDAC/MEF2 Transcriptional Responses* (2007) (211)
- Nitroxyl Improves Cellular Heart Function by Directly Enhancing Cardiac Sarcoplasmic Reticulum Ca2+ Cycling (2007) (207)
- Calibration of indo-1 and resting intracellular [Ca]i in intact rabbit cardiac myocytes. (1995) (204)
- Relaxation of rabbit ventricular muscle by Na-Ca exchange and sarcoplasmic reticulum calcium pump. Ryanodine and voltage sensitivity. (1989) (204)
- Increased Sarcoplasmic Reticulum Calcium Leak but Unaltered Contractility by Acute CaMKII Overexpression in Isolated Rabbit Cardiac Myocytes (2006) (204)
- Na+-Ca2+ Exchange Current and Submembrane [Ca2+] During the Cardiac Action Potential (2002) (200)
- Phospholemman-Phosphorylation Mediates the β-Adrenergic Effects on Na/K Pump Function in Cardiac Myocytes (2005) (198)
- Calcium Signaling in Cardiac Ventricular Myocytes (2005) (195)
- KB-R7943 block of Ca(2+) influx via Na(+)/Ca(2+) exchange does not alter twitches or glycoside inotropy but prevents Ca(2+) overload in rat ventricular myocytes. (2000) (193)
- The effect of Ca2+–calmodulin‐dependent protein kinase II on cardiac excitation–contraction coupling in ferret ventricular myocytes (1997) (190)
- Cardiac myocytes Ca2+ and Na+ regulation in normal and failing hearts. (2006) (188)
- Cardiac Type 2 Inositol 1,4,5-Trisphosphate Receptor (2005) (181)
- Patient-Specific and Genome-Edited Induced Pluripotent Stem Cell-Derived Cardiomyocytes Elucidate Single-Cell Phenotype of Brugada Syndrome. (2016) (178)
- Subcellular [Ca2+]i gradients during excitation-contraction coupling in newborn rabbit ventricular myocytes. (1999) (177)
- Sarcoplasmic Reticulum and Nuclear Envelope Are One Highly Interconnected Ca2+ Store Throughout Cardiac Myocyte (2006) (176)
- Cardiac Alternans Do Not Rely on Diastolic Sarcoplasmic Reticulum Calcium Content Fluctuations (2006) (175)
- Modulation of excitation–contraction coupling by isoproterenol in cardiomyocytes with controlled SR Ca2+ load and Ca2+ current trigger (2004) (172)
- Frequency-dependent acceleration of relaxation in the heart depends on CaMKII, but not phospholamban. (2002) (171)
- The IP3 Receptor Regulates Cardiac Hypertrophy in Response to Select Stimuli (2010) (170)
- Ca2+ spark‐dependent and ‐independent sarcoplasmic reticulum Ca2+ leak in normal and failing rabbit ventricular myocytes (2010) (169)
- Allosteric Regulation of Na/Ca Exchange Current by Cytosolic Ca in Intact Cardiac Myocytes (2001) (167)
- Beta-adrenergic enhancement of sarcoplasmic reticulum calcium leak in cardiac myocytes is mediated by calcium/calmodulin-dependent protein kinase. (2007) (164)
- Intrinsic cytosolic calcium buffering properties of single rat cardiac myocytes. (1994) (163)
- Na+/Ca2+ exchange and Na+/K+-ATPase in the heart (2015) (161)
- Dynamic Regulation of Sodium/Calcium Exchange Function in Human Heart Failure (2003) (160)
- Ca2+/Calmodulin-dependent Protein Kinase II (CaMKII) Regulates Cardiac Sodium Channel NaV1.5 Gating by Multiple Phosphorylation Sites* (2012) (159)
- Intracellular Ca transients in rat cardiac myocytes: role of Na-Ca exchange in excitation-contraction coupling. (1990) (153)
- Termination of Cardiac Ca2+ Sparks: Role of Intra-SR [Ca2+], Release Flux, and Intra-SR Ca2+ Diffusion (2008) (153)
- OPA1 Mutation and Late-Onset Cardiomyopathy: Mitochondrial Dysfunction and mtDNA Instability (2012) (153)
- Regulation of Ca2+ and Na+ in Normal and Failing Cardiac Myocytes (2006) (151)
- Intracellular Na in animal models of hypertrophy and heart failure: contractile function and arrhythmogenesis. (2003) (150)
- Kinetics of FKBP12.6 Binding to Ryanodine Receptors in Permeabilized Cardiac Myocytes and Effects on Ca Sparks (2010) (150)
- Kinetics of [Ca]i decline in cardiac myocytes depend on peak [Ca]i. (1995) (146)
- Calcium and cardiac rhythms: physiological and pathophysiological. (2002) (146)
- Decreased cardiac L-type Ca²⁺ channel activity induces hypertrophy and heart failure in mice. (2012) (145)
- Isolation and characterization of cardiac sarcolemma. (1979) (144)
- Epigenetic Regulation of Phosphodiesterases 2A and 3A Underlies Compromised β-Adrenergic Signaling in an iPSC Model of Dilated Cardiomyopathy. (2015) (144)
- Calmodulin mediates differential sensitivity of CaMKII and calcineurin to local Ca2+ in cardiac myocytes. (2008) (144)
- Intracellular [Na+] and Na+ pump rate in rat and rabbit ventricular myocytes (2002) (142)
- Ca2+/Calmodulin-Dependent Protein Kinase II&dgr; and Protein Kinase D Overexpression Reinforce the Histone Deacetylase 5 Redistribution in Heart Failure (2008) (141)
- FRET biosensor uncovers cAMP nano-domains at β-adrenergic targets that dictate precise tuning of cardiac contractility (2017) (140)
- Inotropic Response to Hypothermia and the Temperature‐Dependence of Ryanodine Action in Isolated Rabbit and Rat Ventricular Muscle: Implications for Excitation‐Contraction Coupling (1987) (136)
- Calcium/Calmodulin-dependent Kinase II Regulation of Cardiac Ion Channels (2009) (136)
- Epac2 Mediates Cardiac &bgr;1-Adrenergic–Dependent Sarcoplasmic Reticulum Ca2+ Leak and Arrhythmia (2013) (135)
- Na‐Ca Exchange and Ca Fluxes during Contraction and Relaxation in Mammalian Ventricular Muscle a (1996) (135)
- Sodium-calcium exchange and sidedness of isolated cardiac sarcolemmal vesicles. (1980) (134)
- Steady-state twitch Ca2+ fluxes and cytosolic Ca2+ buffering in rabbit ventricular myocytes. (1996) (134)
- Local &bgr;-Adrenergic Stimulation Overcomes Source-Sink Mismatch to Generate Focal Arrhythmia (2012) (134)
- Na/Ca exchange and Na/K-ATPase function are equally concentrated in transverse tubules of rat ventricular myocytes. (2003) (133)
- Assessment of intra-SR free [Ca] and buffering in rat heart. (1997) (132)
- Influence of temperature on the calcium sensitivity of the myofilaments of skinned ventricular muscle from the rabbit (1989) (132)
- Metabolic Maturation Media Improve Physiological Function of Human iPSC-Derived Cardiomyocytes (2020) (132)
- Ryanodine receptor phosphorylation at Serine 2030, 2808 and 2814 in rat cardiomyocytes. (2008) (131)
- Spontaneous Ca waves in ventricular myocytes from failing hearts depend on Ca(2+)-calmodulin-dependent protein kinase II. (2010) (131)
- Reverse mode of the sarcoplasmic reticulum calcium pump and load-dependent cytosolic calcium decline in voltage-clamped cardiac ventricular myocytes. (2000) (131)
- Effects of FK-506 on contraction and Ca2+ transients in rat cardiac myocytes. (1996) (130)
- Intracellular Ca2+ transients during rapid cooling contractures in guinea‐pig ventricular myocytes. (1989) (128)
- A Critical Function for Ser-282 in Cardiac Myosin Binding Protein-C Phosphorylation and Cardiac Function (2011) (127)
- Intracellular Ca2+ increases the mitochondrial NADH concentration during elevated work in intact cardiac muscle. (1997) (125)
- Na⁺ transport in the normal and failing heart - remember the balance. (2013) (125)
- Temperature and relative contributions of Ca transport systems in cardiac myocyte relaxation. (1996) (124)
- Differences in Ca(2+)-handling and sarcoplasmic reticulum Ca(2+)-content in isolated rat and rabbit myocardium. (2000) (124)
- Ca/Calmodulin Kinase II Differentially Modulates Potassium Currents (2009) (123)
- Divergent Regulation of Ryanodine Receptor 2 Calcium Release Channels by Arrhythmogenic Human Calmodulin Missense Mutants (2014) (123)
- Mechanochemotransduction During Cardiomyocyte Contraction Is Mediated by Localized Nitric Oxide Signaling (2014) (122)
- Targets for therapy in sarcomeric cardiomyopathies. (2015) (121)
- Passive Ca buffering and SR Ca uptake in permeabilized rabbit ventricular myocytes. (1993) (118)
- Phospholamban Ablation Rescues Sarcoplasmic Reticulum Ca2+ Handling but Exacerbates Cardiac Dysfunction in CaMKII&dgr;C Transgenic Mice (2010) (117)
- Sarcoplasmic reticulum Ca2+ uptake and thapsigargin sensitivity in permeabilized rabbit and rat ventricular myocytes. (1993) (116)
- SR Ca loading in cardiac muscle preparations based on rapid-cooling contractures. (1989) (116)
- Modulation of SR Ca release by luminal Ca and calsequestrin in cardiac myocytes: effects of CASQ2 mutations linked to sudden cardiac death. (2008) (115)
- Calcium and cardiomyopathies. (2007) (115)
- Expression and Phosphorylation of the Na-Pump Regulatory Subunit Phospholemman in Heart Failure (2005) (115)
- Biosensors to Measure Inositol 1,4,5-Trisphosphate Concentration in Living Cells with Spatiotemporal Resolution* (2006) (114)
- The role of phospholipids in the Ca2+ binding of isolated cardiac sarcolemma. (1980) (113)
- Upregulated Na/Ca exchange is involved in both contractile dysfunction and arrhythmogenesis in heart failure (2002) (112)
- Ca(2+) influx through Ca(2+) channels in rabbit ventricular myocytes during action potential clamp: influence of temperature. (1999) (112)
- Downregulation of sarcoplasmic reticulum Ca(2+)-ATPase during progression of left ventricular hypertrophy. (1997) (111)
- Ca2+ diffusion and sarcoplasmic reticulum transport both contribute to [Ca2+]i decline during Ca2+ sparks in rat ventricular myocytes. (1996) (110)
- Simultaneous measurements of mitochondrial NADH and Ca(2+) during increased work in intact rat heart trabeculae. (2002) (108)
- Mechanisms contributing to the cardiac inotropic effect of Na pump inhibition and reduction of extracellular Na (1987) (107)
- Hyperamylinemia Contributes to Cardiac Dysfunction in Obesity and Diabetes: A Study in Humans and Rats (2012) (107)
- Can Ca entry via Na-Ca exchange directly activate cardiac muscle contraction? (1988) (107)
- Cardiac Na/Ca exchange function in rabbit, mouse and man: what's the difference? (2002) (106)
- CaMKII is responsible for activity-dependent acceleration of relaxation in rat ventricular myocytes. (1995) (106)
- Sarcoplasmic Reticulum Calcium Overloading in Junctin Deficiency Enhances Cardiac Contractility but Increases Ventricular Automaticity (2007) (105)
- Measuring Local Gradients of Intramitochondrial [Ca2+] in Cardiac Myocytes During Sarcoplasmic Reticulum Ca2+ Release (2012) (105)
- Increased work in cardiac trabeculae causes decreased mitochondrial NADH fluorescence followed by slow recovery. (1996) (105)
- Arrhythmogenic Effects of &bgr;2-Adrenergic Stimulation in the Failing Heart Are Attributable to Enhanced Sarcoplasmic Reticulum Ca Load (2008) (105)
- Optical Mapping of Sarcoplasmic Reticulum Ca2+ in the Intact Heart: Ryanodine Receptor Refractoriness During Alternans and Fibrillation (2014) (104)
- Simulation of Ca-calmodulin-dependent protein kinase II on rabbit ventricular myocyte ion currents and action potentials. (2007) (104)
- Cytosolic and mitochondrial Ca2+ signals in patch clamped mammalian ventricular myocytes (1998) (104)
- Dynamic Calcium Movement Inside Cardiac Sarcoplasmic Reticulum During Release (2011) (103)
- Sarcoplasmic Reticulum Ca 2 and Heart Failure Roles of Diastolic Leak and Ca 2 Transport (2003) (103)
- Late Sodium Current Contributes to the Reverse Rate-Dependent Effect of IKr Inhibition on Ventricular Repolarization (2011) (103)
- Requirement for Ca 2+/calmodulin-dependent kinase II in the transition from pressure overload-induced cardiac hypertrophy to heart failure in mice (Journal of Clinical Investigation (2009) 119, 5, (1230-1240) doi: 10.1172/JCI38022) (2012) (102)
- Twitch-dependent SR Ca accumulation and release in rabbit ventricular myocytes. (1993) (101)
- Indo-1 binding to protein in permeabilized ventricular myocytes alters its spectral and Ca binding properties. (1992) (101)
- Regulation of the cloned L‐type cardiac calcium channel by cyclic‐AMP‐dependent protein kinase (1994) (100)
- Altered myocardial Ca2+ cycling after left ventricular assist device support in the failing human heart. (2004) (98)
- Role of sodium and calcium dysregulation in tachyarrhythmias in sudden cardiac death. (2015) (98)
- Regulation of cardiac sarcoplasmic reticulum Ca release by luminal [Ca] and altered gating assessed with a mathematical model. (2005) (96)
- Free and bound intracellular calmodulin measurements in cardiac myocytes. (2007) (95)
- Ryanodine and the calcium content of cardiac SR assessed by caffeine and rapid cooling contractures. (1987) (95)
- When is cAMP not cAMP? Effects of compartmentalization. (2001) (93)
- Ryanodine receptor S2808 phosphorylation in heart failure: smoking gun or red herring. (2012) (92)
- Spatiotemporal characteristics of SR Ca(2+) uptake and release in detubulated rat ventricular myocytes. (2005) (92)
- Rate of diastolic Ca release from the sarcoplasmic reticulum of intact rabbit and rat ventricular myocytes. (1995) (91)
- Comparison of sarcolemmal calcium channel current in rabbit and rat ventricular myocytes. (1996) (91)
- Cardiac myocyte volume, Ca2+ fluxes, and sarcoplasmic reticulum loading in pressure-overload hypertrophy. (1997) (91)
- CaMKII inhibition targeted to the sarcoplasmic reticulum inhibits frequency-dependent acceleration of relaxation and Ca2+ current facilitation. (2007) (90)
- Paradoxical twitch potentiation after rest in cardiac muscle: increased fractional release of SR calcium. (1993) (89)
- Differential distribution and regulation of mouse cardiac Na+/K+-ATPase α1 and α2 subunits in T-tubule and surface sarcolemmal membranes (2007) (88)
- Competition and redistribution among calcium transport systems in rabbit cardiac myocytes. (1993) (88)
- Cardiac contractility and sarcolemmal calcium binding in several cardiac muscle preparations. (1981) (87)
- Expression of Inducible Nitric Oxide Synthase Depresses &bgr;-Adrenergic–Stimulated Calcium Release From the Sarcoplasmic Reticulum in Intact Ventricular Myocytes (2001) (86)
- Na-Ca exchange is required for rest-decay but not for rest-potentiation of twitches in rabbit and rat ventricular myocytes. (1994) (86)
- Ca flux, contractility, and excitation-contraction coupling in hypertrophic rat ventricular myocytes. (1998) (85)
- Temperature dependence of myofilament Ca sensitivity of rat, guinea pig, and frog ventricular muscle. (1990) (85)
- Akt regulates L-type Ca2+ channel activity by modulating Cavα1 protein stability (2009) (85)
- Phospholemman-Mediated Activation of Na/K-ATPase Limits [Na]i and Inotropic State During &bgr;-Adrenergic Stimulation in Mouse Ventricular Myocytes (2008) (84)
- Temporal dissociation of frequency-dependent acceleration of relaxation and protein phosphorylation by CaMKII. (2007) (84)
- Post-translational modifications of the cardiac Na channel: contribution of CaMKII-dependent phosphorylation to acquired arrhythmias. (2013) (83)
- Stretch-dependent slow force response in isolated rabbit myocardium is Na+ dependent. (2003) (83)
- Oxidation of ryanodine receptor (RyR) and calmodulin enhance Ca release and pathologically alter, RyR structure and calmodulin affinity. (2015) (82)
- Mitochondrial free calcium regulation during sarcoplasmic reticulum calcium release in rat cardiac myocytes. (2009) (82)
- Ranolazine for Congenital and Acquired Late INa-Linked Arrhythmias: In Silico Pharmacological Screening (2013) (82)
- Relaxation in ferret ventricular myocytes: unusual interplay among calcium transport systems. (1994) (81)
- Correction of proton and Ca association constants of EGTA for temperature and ionic strength. (1989) (81)
- The inotropic effect of cardioactive glycosides in ventricular myocytes requires Na+–Ca2+ exchanger function (2006) (81)
- Myocyte Nitric Oxide Synthase 2 Contributes to Blunted β-Adrenergic Response in Failing Human Hearts by Decreasing Ca2+ Transients (2004) (81)
- Location Matters: Clarifying the Concept of Nuclear and Cytosolic CaMKII Subtypes (2011) (80)
- Na(+)/K)+)-ATPase α2-isoform preferentially modulates Ca2(+) transients and sarcoplasmic reticulum Ca2(+) release in cardiac myocytes. (2012) (80)
- GRAM domain proteins specialize functionally distinct ER-PM contact sites in human cells (2018) (79)
- Calcium transport and the regulation of cardiac contractility in teleosts: a comparison with higher vertebrates (1991) (79)
- Chasing cardiac physiology and pathology down the CaMKII cascade. (2015) (79)
- Phospholemman Phosphorylation Mediates the Protein Kinase C–Dependent Effects on Na+/K+ Pump Function in Cardiac Myocytes (2006) (79)
- Constitutive BDNF/TrkB signaling is required for normal cardiac contraction and relaxation (2015) (78)
- Fluorescence Resonance Energy Transfer–Based Sensor Camui Provides New Insight Into Mechanisms of Calcium/Calmodulin-Dependent Protein Kinase II Activation in Intact Cardiomyocytes (2011) (78)
- S-Nitrosylation Induces Both Autonomous Activation and Inhibition of Calcium/Calmodulin-dependent Protein Kinase II δ* (2015) (77)
- AKAP150 Contributes to Enhanced Vascular Tone by Facilitating Large-Conductance Ca2+-Activated K+ Channel Remodeling in Hyperglycemia and Diabetes Mellitus (2013) (77)
- Epac enhances excitation-transcription coupling in cardiac myocytes. (2012) (77)
- Modelling diastolic dysfunction in induced pluripotent stem cell-derived cardiomyocytes from hypertrophic cardiomyopathy patients. (2019) (77)
- Intracellular calcium and sodium activity in sheep heart Purkinje fibres (1982) (77)
- Transgenic Rabbit Model for Human Troponin I–Based Hypertrophic Cardiomyopathy (2005) (76)
- Transmission of information from cardiac dihydropyridine receptor to ryanodine receptor: evidence from BayK 8644 effects on resting Ca(2+) sparks. (2000) (75)
- Calcium Cycling in Heart Failure: The Arrhythmia Connection (2002) (75)
- Cardiac Myocyte Z-Line Calmodulin Is Mainly RyR2-Bound, and Reduction Is Arrhythmogenic and Occurs in Heart Failure (2014) (75)
- Ca2+ cycling between sarcoplasmic reticulum and mitochondria in rabbit cardiac myocytes. (1993) (75)
- Systems Approach to Understanding Electromechanical Activity in the Human Heart: A National Heart, Lung, and Blood Institute Workshop Summary (2008) (75)
- Potassium currents in the heart: functional roles in repolarization, arrhythmia and therapeutics (2017) (74)
- Individual Cardiac Mitochondria Undergo Rare Transient Permeability Transition Pore Openings. (2016) (73)
- Histidine-rich Ca binding protein: a regulator of sarcoplasmic reticulum calcium sequestration and cardiac function. (2006) (72)
- Functional analysis of Na+/K+-ATPase isoform distribution in rat ventricular myocytes. (2007) (72)
- Role of the sarcoplasmic reticulum in contraction and relaxation of immature rabbit ventricular myocytes. (1997) (71)
- Uncoupling cation effects on cardiac contractility and sarcolemmal Ca2+ binding. (1979) (71)
- Early transient depletion of extracellular Ca during individual cardiac muscle contractions. (1983) (70)
- Isoform Specificity of the Na/K-ATPase Association and Regulation by Phospholemman* (2009) (70)
- Early Remodeling of Perinuclear Ca2+ Stores and Nucleoplasmic Ca2+ Signaling During the Development of Hypertrophy and Heart Failure (2014) (69)
- Isoproterenol does not enhance Ca-dependent Na/Ca exchange current in intact rabbit ventricular myocytes. (2005) (69)
- Dihydropyridine receptors are primarily functional L-type calcium channels in rabbit ventricular myocytes. (1991) (69)
- CaMKII-dependent phosphorylation of RyR2 promotes targetable pathological RyR2 conformational shift. (2016) (68)
- CaMKIIδ mediates β-adrenergic effects on RyR2 phosphorylation and SR Ca(2+) leak and the pathophysiological response to chronic β-adrenergic stimulation. (2015) (68)
- The mechanism of ryanodine action in rabbit ventricular muscle evaluated with Ca-selective microelectrodes and rapid cooling contractures. (1987) (67)
- Ca sparks do not explain all ryanodine receptor-mediated SR Ca leak in mouse ventricular myocytes. (2010) (67)
- Na/K pump current and [Na](i) in rabbit ventricular myocytes: local [Na](i) depletion and Na buffering. (2003) (67)
- Voltage Dependence of Cardiac Excitation–Contraction Coupling: Unitary Ca2+ Current Amplitude and Open Channel Probability (2007) (67)
- Nitric Oxide-Dependent Activation of CaMKII Increases Diastolic Sarcoplasmic Reticulum Calcium Release in Cardiac Myocytes in Response to Adrenergic Stimulation (2014) (67)
- Na/K-ATPase--an integral player in the adrenergic fight-or-flight response. (2009) (66)
- Phospholamban Oligomerization, Quaternary Structure, and Sarco(endo)plasmic Reticulum Calcium ATPase Binding Measured by Fluorescence Resonance Energy Transfer in Living Cells* (2008) (66)
- Na/Ca Exchange in Heart Failure (2002) (66)
- The real estate of NOS signaling: location, location, location. (2003) (65)
- Rapid cooling contractures as an index of sarcoplasmic reticulum calcium content in rabbit ventricular myocytes. (1989) (65)
- Protein kinase inhibitors reduce SR Ca transport in permeabilized cardiac myocytes. (1994) (65)
- Atherosclerosis exacerbates arrhythmia following myocardial infarction: Role of myocardial inflammation. (2015) (64)
- Cardiac ryanodine receptor phosphorylation: target sites and functional consequences. (2006) (64)
- Calmodulin binding proteins provide domains of local Ca2+ signaling in cardiac myocytes. (2012) (64)
- Akt regulates L-type Ca2+ channel activity by modulating Cavα1 protein stability (2009) (64)
- Complex electrophysiological remodeling in postinfarction ischemic heart failure (2018) (64)
- Integrated Ca2+ Management in Cardiac Myocytes (2004) (62)
- Excessive Sarcoplasmic/Endoplasmic Reticulum Ca2+-ATPase Expression Causes Increased Sarcoplasmic Reticulum Ca2+ Uptake but Decreases Myocyte Shortening (2004) (62)
- Control of Maximum Sarcoplasmic Reticulum Ca Load in Intact Ferret Ventricular Myocytes (1998) (61)
- How to make and use calcium-specific mini- and microelectrodes. (1994) (61)
- Calcium movements inside the sarcoplasmic reticulum of cardiac myocytes. (2013) (61)
- CaMKII signaling in heart diseases: Emerging role in diabetic cardiomyopathy. (2019) (61)
- Potassium channels in the heart: structure, function and regulation (2017) (61)
- Species Differences and the Role of Sodium‐Calcium Exchange in Cardiac Muscle Relaxation a (1991) (61)
- Postrest inotropy in rabbit ventricle: Na+-Ca2+ exchange determines sarcoplasmic reticulum Ca2+ content. (1986) (60)
- Impaired relaxation in transgenic mice overexpressing junctin. (2003) (60)
- Ca current facilitation during postrest recovery depends on Ca entry. (1990) (60)
- Partial inhibition of sarcoplasmic reticulum ca release evokes long-lasting ca release events in ventricular myocytes: role of luminal ca in termination of ca release. (2008) (60)
- Nuclear CaMKII enhances histone H3 phosphorylation and remodels chromatin during cardiac hypertrophy (2013) (60)
- Nuclear Translocation of Cardiac G Protein-Coupled Receptor Kinase 5 Downstream of Select Gq-Activating Hypertrophic Ligands Is a Calmodulin-Dependent Process (2013) (60)
- Novel Epac fluorescent ligand reveals distinct Epac1 vs. Epac2 distribution and function in cardiomyocytes (2015) (58)
- Action potential duration determines sarcoplasmic reticulum Ca2+ reloading in mammalian ventricular myocytes (2004) (58)
- How does stochastic ryanodine receptor-mediated Ca leak fail to initiate a Ca spark? (2011) (58)
- Effects of thapsigargin and cyclopiazonic acid on twitch force and sarcoplasmic reticulum Ca2+ content of rabbit ventricular muscle. (1993) (57)
- Positive and negative effects of nitric oxide on Ca2+ sparks: influence of β-adrenergic stimulation (2001) (57)
- Na+ channel function, regulation, structure, trafficking and sequestration (2015) (57)
- Relaxation in ferret ventricular myocytes: role of the sarcolemmal Ca ATPase (1995) (57)
- β-adrenergic stimulation activates early afterdepolarizations transiently via kinetic mismatch of PKA targets. (2013) (56)
- Cardiac hypertrophy and heart failure development through Gq and CaM kinase II signaling. (2010) (56)
- Ankyrin-B reduction enhances Ca spark-mediated SR Ca release promoting cardiac myocyte arrhythmic activity. (2012) (56)
- signaling in cardiac myocyte excitation- transcription coupling (2006) (55)
- Cyclic stretch down-regulates calcium transporter gene expression in neonatal rat ventricular myocytes. (1998) (55)
- Hyperglycemia Acutely Increases Cytosolic Reactive Oxygen Species via O-linked GlcNAcylation and CaMKII Activation in Mouse Ventricular Myocytes (2020) (55)
- The human phospholamban Arg14-deletion mutant localizes to plasma membrane and interacts with the Na/K-ATPase. (2012) (54)
- Na/K pump-induced [Na](i) gradients in rat ventricular myocytes measured with two-photon microscopy. (2004) (54)
- Phospholemman Phosphorylation Alters Its Fluorescence Resonance Energy Transfer with the Na/K-ATPase Pump* (2006) (53)
- Overexpression of the Na+/K+ ATPase &agr;2 But Not &agr;1 Isoform Attenuates Pathological Cardiac Hypertrophy and Remodeling (2014) (53)
- Stress Signaling JNK2 Crosstalk With CaMKII Underlies Enhanced Atrial Arrhythmogenesis (2018) (53)
- Phospholamban is required for CaMKII-dependent recovery of Ca transients and SR Ca reuptake during acidosis in cardiac myocytes. (2004) (53)
- Targeting of protein phosphatases PP2A and PP2B to the C-terminus of the L-type calcium channel Ca v1.2. (2010) (53)
- Na:Ca Stoichiometry and Cytosolic Ca‐Dependent Activation of NCX in Intact Cardiomyocytes (2007) (52)
- Ca2+ current facilitation is CaMKII-dependent and has arrhythmogenic consequences (2014) (52)
- Sarcoplasmic reticulum Ca release in intact ventricular myocytes. (2002) (52)
- Effect of extracellular calcium on myocardial mechanical function in the neonatal rabbit. (1982) (52)
- Frequency-dependent changes in contribution of SR Ca2+ to Ca2+ transients in failing human myocardium assessed with ryanodine. (1998) (51)
- Modeling the isolated cardiac myocyte. (2004) (51)
- Effects of left ventricular hypertrophy on force and Ca2+ handling in isolated rat myocardium. (1998) (51)
- Ca regulation in cardiac muscle. (1991) (51)
- Extracellular potassium dependence of the Na+-K+-ATPase in cardiac myocytes: isoform specificity and effect of phospholemman. (2009) (51)
- Differential distribution and regulation of mouse cardiac Na+/K+-ATPase alpha1 and alpha2 subunits in T-tubule and surface sarcolemmal membranes. (2007) (50)
- Subcellular [Ca 2 (cid:49) ] i Gradients During Excitation-Contraction Coupling in Newborn Rabbit Ventricular Myocytes (1999) (50)
- The mitochondrial calcium uniporter underlies metabolic fuel preference in skeletal muscle. (2018) (50)
- β-Adrenergic induced SR Ca2+ leak is mediated by an Epac-NOS pathway. (2017) (50)
- β-adrenergic effects on cardiac myofilaments and contraction in an integrated rabbit ventricular myocyte model. (2015) (50)
- Acute β-Adrenergic Activation Triggers Nuclear Import of Histone Deacetylase 5 and Delays Gq-induced Transcriptional Activation* (2012) (50)
- Cardiac Submembrane [Na+] Transients Sensed by Na+-Ca2+ Exchange Current (2003) (50)
- Theoretical study of L‐type Ca2+ current inactivation kinetics during action potential repolarization and early afterdepolarizations (2012) (50)
- Nitric oxide regulates cardiac intracellular Na+ and Ca2 + by modulating Na/K ATPase via PKCε and phospholemman-dependent mechanism☆ (2013) (49)
- Antiarrhythmic effects of interleukin 1 inhibition after myocardial infarction. (2017) (49)
- Dynamic changes in free Ca-calmodulin levels in adult cardiac myocytes. (2006) (49)
- β-adrenergic regulation of late Na+ current during cardiac action potential is mediated by both PKA and CaMKII. (2018) (48)
- Pentameric Assembly of Phospholamban Facilitates Inhibition of Cardiac Function in Vivo * (1998) (48)
- Analysis of the mechanisms of mitochondrial NADH regulation in cardiac trabeculae. (1999) (48)
- Size Matters: Ryanodine Receptor Cluster Size Affects Arrhythmogenic Sarcoplasmic Reticulum Calcium Release (2018) (48)
- Electrodiffusion of ions approaching the mouth of a conducting membrane channel. (1988) (48)
- Formation of Spatially Discordant Alternans Due to Fluctuations and Diffusion of Calcium (2013) (48)
- Transgenic CaMKII C Overexpression Uniquely Alters Cardiac Myocyte Ca (2003) (48)
- Diffusion around a cardiac calcium channel and the role of surface bound calcium. (1991) (47)
- High-Throughput Screens to Discover Small-Molecule Modulators of Ryanodine Receptor Calcium Release Channels (2017) (46)
- Intracellular signalling mechanism responsible for modulation of sarcolemmal ATP‐sensitive potassium channels by nitric oxide in ventricular cardiomyocytes (2014) (46)
- Interplay of voltage and Ca-dependent inactivation of L-type Ca current. (2010) (46)
- Modification of temperature dependence of myofilament Ca sensitivity by troponin C replacement. (1990) (45)
- Bay K 8644 increases resting Ca2+ spark frequency in ferret ventricular myocytes independent of Ca influx: contrast with caffeine and ryanodine effects. (1998) (45)
- Na/Ca exchange in heart failure: contractile dysfunction and arrhythmogenesis. (2002) (45)
- Spatiotemporally Distinct Protein Kinase D Activation in Adult Cardiomyocytes in Response to Phenylephrine and Endothelin* (2011) (45)
- Biphasic Contractions Induced by Milrinone at Low Temperature in Ferret Ventricular Muscle: Role of the Sarcoplasmic Reticulum and Transmembrane Calcium Influx (1986) (45)
- Phospholamban Decreases the Energetic Efficiency of the Sarcoplasmic Reticulum Ca Pump* (2001) (45)
- Diastolic SR Ca efflux in atrial pacemaker cells and Ca-overloaded myocytes. (1997) (45)
- Impaired contractile function and calcium handling in hearts of cardiac-specific calcineurin b1-deficient mice. (2009) (44)
- Differential Integration of Ca2+-Calmodulin Signal in Intact Ventricular Myocytes at Low and High Affinity Ca2+-Calmodulin Targets* (2008) (44)
- Deranged sodium to sudden death (2015) (44)
- Junctional Cleft [Ca2+]i Measurements Using Novel Cleft-Targeted Ca2+ Sensors (2014) (43)
- Binding of Ca2+ and Na+ to sarcolemmal membranes: relation to control of myocardial contractility. (1980) (43)
- Genetically Encoded Biosensors Reveal PKA Hyperphosphorylation on the Myofilaments in Rabbit Heart Failure. (2016) (43)
- Myosin heavy chain gene expression in neonatal rat heart cells: effects of [Ca2+]i and contractile activity. (1997) (41)
- Chronic SR Ca2+‐ATPase Inhibition Causes Adaptive Changes in Cellular Ca2+ Transport (2003) (41)
- Regulatory role of phospholamban in the efficiency of cardiac sarcoplasmic reticulum Ca2+ transport. (2000) (41)
- Factors That Control Sarcoplasmic Reticulum Calcium Release in Intact Ventricular Myocytesa (1998) (41)
- Nonequilibrium Reactivation of Na+ Current Drives Early Afterdepolarizations in Mouse Ventricle (2014) (40)
- Protein kinase inhibitor H-89 reverses forskolin stimulation of cardiac L-type calcium current. (1995) (40)
- Effect of acetylstrophanthidin on twitches, microscopic tension fluctuations and cooling contractures in rabbit ventricle. (1988) (40)
- Atrial-selective targeting of arrhythmogenic phase-3 early afterdepolarizations in human myocytes. (2016) (40)
- Whole-Cell cAMP and PKA Activity are Epiphenomena, Nanodomain Signaling Matters. (2019) (39)
- Cumulative Depletions of Extracellular Calcium in Rabbit Ventricular Muscle Monitored with Calcium‐ Selective Microelectrodes (1986) (39)
- Contractile arrest increases sarcoplasmic reticulum calcium uptake and SERCA2 gene expression in cultured neonatal rat heart cells. (1994) (39)
- Phorbol 12-myristate 13-acetate alters SR Ca(2+)-ATPase gene expression in cultured neonatal rat heart cells. (1996) (39)
- FRET detection of calmodulin binding to the cardiac RyR2 calcium release channel. (2011) (38)
- CaMKII Phosphorylation of Na(V)1.5: Novel in Vitro Sites Identified by Mass Spectrometry and Reduced S516 Phosphorylation in Human Heart Failure. (2015) (38)
- Passive Ca2+ binding in ventricular myocardium of neonatal and adult rats. (1998) (38)
- KB-R 7943 Block of Ca 2 1 Influx Via Na 1 / Ca 2 1 Exchange Does Not Alter Twitches or Glycoside Inotropy but Prevents Ca 2 1 Overload in Rat Ventricular Myocytes (2000) (38)
- Calmodulin and Ca2+/calmodulin kinases in the heart - physiology and pathophysiology. (2007) (37)
- Mitochondrial Quality Control in Aging and Heart Failure: Influence of Ketone Bodies and Mitofusin-Stabilizing Peptides (2018) (37)
- Adenoviral Gene Transfer of Mutant Phospholamban Rescues Contractile Dysfunction in Failing Rabbit Myocytes With Relatively Preserved SERCA Function (2005) (37)
- The late sodium current in heart failure: pathophysiology and clinical relevance (2014) (36)
- Regulation of mitochondrial [NADH] by cytosolic [Ca2+] and work in trabeculae from hypertrophic and normal rat hearts. (1998) (36)
- Na+ transport in cardiac myocytes; Implications for excitation‐contraction coupling (2009) (36)
- Subcellular properties of [Ca2+]i transients in phospholamban-deficient mouse ventricular cells. (1998) (36)
- Rabbit models of heart disease (2008) (36)
- Cardiac Na+–Ca2+ exchanger: dynamics of Ca2+‐dependent activation and deactivation in intact myocytes (2013) (35)
- Ca²⁺-calmodulin-dependent protein kinase II regulation of cardiac excitation-transcription coupling. (2011) (35)
- Intra–Sarcoplasmic Reticulum Free [Ca2+] and Buffering in Arrhythmogenic Failing Rabbit Heart (2007) (35)
- Subcellular properties of [Ca2+]itransients in phospholamban-deficient mouse ventricular cells. (1998) (34)
- Nuclear Calcium in Cardiac Myocytes (2015) (34)
- Control of histone H3 phosphorylation by CaMKIIδ in response to haemodynamic cardiac stress (2014) (34)
- Functional interconversion of rest decay and ryanodine effects in rabbit and rat ventricle depends on Na/Ca exchange. (1990) (33)
- Ca transport during contraction and relaxation in mammalian ventricular muscle (2004) (33)
- Isoform- and tissue-specific regulation of the Ca(2+)-sensitive transcription factor NFAT in cardiac myocytes and heart failure. (2010) (33)
- Cardiac-specific Conditional Knockout of the 18-kDa Mitochondrial Translocator Protein Protects from Pressure Overload Induced Heart Failure (2018) (32)
- Role of phospholemman phosphorylation sites in mediating kinase-dependent regulation of the Na+-K+-ATPase. (2010) (32)
- Coordinated Feet and the Dance of Ryanodine Receptors (1998) (32)
- Excitation‐Contraction Coupling in Heart Cells (1990) (32)
- Decreased inward rectifying K+ current and increased ryanodine receptor sensitivity synergistically contribute to sustained focal arrhythmia in the intact rabbit heart (2015) (32)
- In Cardiomyocytes, Binding of Unzipping Peptide Activates Ryanodine Receptor 2 and Reciprocally Inhibits Calmodulin Binding (2013) (31)
- Phosphomimetic Mutations Enhance Oligomerization of Phospholemman and Modulate Its Interaction with the Na/K-ATPase* (2011) (31)
- Modelling calcium microdomains using homogenisation. (2007) (31)
- CaMKIIδC slows [Ca]i decline in cardiac myocytes by promoting Ca sparks. (2012) (30)
- Intracellular β1-Adrenergic Receptors and Organic Cation Transporter 3 Mediate Phospholamban Phosphorylation to Enhance Cardiac Contractility (2020) (30)
- Human atrial fibrillation: insights from computational electrophysiological models. (2011) (30)
- Sodium and the heart: a hidden key factor in cardiac regulation. (2003) (30)
- A 20/20 view of ANT function in mitochondrial biology and necrotic cell death. (2020) (29)
- Altered Repolarization Reserve in Failing Rabbit Ventricular Myocytes: Calcium and &bgr;-Adrenergic Effects on Delayed- and Inward-Rectifier Potassium Currents (2018) (29)
- Targeted inhibition of sarcoplasmic reticulum CaMKII activity results in alterations of Ca2+ homeostasis and cardiac contractility. (2006) (28)
- Slow [Na]i Changes and Positive Feedback Between Membrane Potential and [Ca]i Underlie Intermittent Early Afterdepolarizations and Arrhythmias (2015) (28)
- Hyperglycemia regulates cardiac K+ channels via O-GlcNAc-CaMKII and NOX2-ROS-PKC pathways (2020) (28)
- Na/Ca Exchange Function in Intact Ventricular Myocytes (2002) (28)
- Possible functional linkage between the cardiac dihydropyridine and ryanodine receptor: acceleration of rest decay by Bay K 8644. (1996) (27)
- Epac 2 Mediates Cardiac β 1-Adrenergic – Dependent Sarcoplasmic Reticulum Ca 2 + Leak and Arrhythmia (2013) (27)
- Positive and negative effects of nitric oxide on Ca(2+) sparks: influence of beta-adrenergic stimulation. (2001) (27)
- Arrhythmogenic transient dynamics in cardiac myocytes. (2014) (27)
- Intrafibrillar and perinuclear mitochondrial heterogeneity in adult cardiac myocytes. (2019) (27)
- Diabetic microcirculatory disturbances and pathologic erythropoiesis are provoked by deposition of amyloid-forming amylin in red blood cells and capillaries. (2019) (26)
- SR-targeted CaMKII inhibition improves SR Ca²+ handling, but accelerates cardiac remodeling in mice overexpressing CaMKIIδC. (2011) (26)
- Quantitative analysis of the Ca2+‐dependent regulation of delayed rectifier K+ current IKs in rabbit ventricular myocytes (2017) (26)
- Sex differences in repolarization and slow delayed rectifier potassium current and their regulation by sympathetic stimulation in rabbits (2013) (26)
- Temperature-dependent Activation of Neurons by Continuous Near-infrared Laser (2008) (25)
- Enhanced Depolarization Drive in Failing Rabbit Ventricular Myocytes: Calcium-Dependent and &bgr;-Adrenergic Effects on Late Sodium, L-Type Calcium, and Sodium-Calcium Exchange Currents (2019) (25)
- Quantitative analysis of regional variability in the distribution of transverse tubules in rabbit myocardium (1991) (25)
- Disease-associated mutations in Niemann-Pick type C1 alter ER calcium signaling and neuronal plasticity (2019) (25)
- Effect of intracellular Ca2+ and action potential duration on L-type Ca2+ channel inactivation and recovery from inactivation in rabbit cardiac myocytes. (2007) (25)
- Excitation-Contraction Coupling and Cardiac Contractile Force (1993) (25)
- Targeted ablation of the histidine-rich Ca2+-binding protein (HRC) gene is associated with abnormal SR Ca2+-cycling and severe pathology under pressure-overload stress (2013) (25)
- Calcium Influx via INCX Is Favored in Failing Human Ventricular Myocytes (2002) (24)
- CaMKII inhibition in heart failure makes jump to human. (2010) (24)
- Effects of rest duration and ryanodine on changes of extracellular [Ca] in cardiac muscle from rabbits. (1987) (24)
- Going to cAMP just got more complicated (2007) (24)
- Sarcoplasmic Reticulum Structure and Functional Properties that Promote Long-Lasting Calcium Sparks. (2016) (23)
- Control of Cardiac Contraction by SR Ca Release and Sarcolemmal Ca Fluxes (1993) (23)
- Importance of small heat shock protein 20 (hsp20) C-terminal extension in cardioprotection. (2007) (23)
- Cardiac Inotropy and Ca Mismanagement (2001) (23)
- Mechano‐electric and mechano‐chemo‐transduction in cardiomyocytes (2019) (23)
- MCUb Induction Protects the Heart From Postischemic Remodeling (2020) (23)
- Cardiac pacemaking: If vs. Ca2+, is it really that simple? (2003) (22)
- RyR1-targeted drug discovery pipeline integrating FRET-based high-throughput screening and human myofiber dynamic Ca2+ assays (2020) (22)
- Size Matters: Ryanodine Receptor Cluster Size Heterogeneity Potentiates Calcium Waves. (2019) (22)
- BAY K 8644 depresses excitation-contraction coupling in cardiac muscle. (1996) (22)
- Dynamical effects of calcium‐sensitive potassium currents on voltage and calcium alternans (2017) (22)
- Visualizing CaMKII and CaM activity: a paradigm of compartmentalized signaling (2013) (22)
- A cardiac dihydropyridine receptor II‐III loop peptide inhibits resting Ca2+ sparks in ferret ventricular myocytes (2001) (21)
- While systolic cardiomyocyte function is preserved, diastolic myocyte function and recovery from acidosis are impaired in CaMKIIδ-KO mice. (2013) (21)
- A Novel Computational Model of the Human Ventricular Action Potential and Ca transient (2009) (21)
- Beyond beta blockers (2005) (21)
- Ca2+ influx via the L‐type Ca2+ channel during tail current and above current reversal potential in ferret ventricular myocytes (2000) (20)
- Can the sodium-calcium exchanger initiate or suppress calcium sparks in cardiac myocytes? (2012) (20)
- CaMKIIδC Drives Early Adaptive Ca2+ Change and Late Eccentric Cardiac Hypertrophy (2020) (20)
- S100A1 Protein Does Not Compete with Calmodulin for Ryanodine Receptor Binding but Structurally Alters the Ryanodine Receptor·Calmodulin Complex* (2016) (19)
- Faculty Opinions recommendation of Beta-adrenergic stimulation of L-type Ca2+ channels in cardiac myocytes requires the distal carboxyl terminus of alpha1C but not serine 1928. (2006) (19)
- Ca2+ sparks. Jumping the gap from the cell to cardiac muscle. (1997) (19)
- Effects of left ventricular hypertrophy on force and Ca2+ handling in isolated rat myocardium. (1998) (19)
- Nuclear Calcium/Calmodulin-dependent Protein Kinase II Signaling Enhances Cardiac Progenitor Cell Survival and Cardiac Lineage Commitment* (2015) (19)
- Phorbol ester and endothelin-1 alter functional expression of Na+/Ca2+ exchange, K+, and Ca2+ currents in cultured neonatal rat myocytes. (2011) (19)
- Dynamics of sodium current mediated early afterdepolarizations (2017) (19)
- Na+/K+-ATPase E960 and phospholemman F28 are critical for their functional interaction (2012) (18)
- Mitochondria: from basic biology to cardiovascular disease. (2009) (18)
- Different paths, same destination: divergent action potential responses produce conserved cardiac fight‐or‐flight response in mouse and rabbit hearts (2019) (18)
- Cardiomyocyte Na+ and Ca2+ mishandling drives vicious cycle involving CaMKII, ROS, and ryanodine receptors (2021) (18)
- Modulation of Contractility in Failing Human Myocytes by Reverse‐Mode Na/Ca Exchange (2002) (18)
- The beat goes on: diastolic noise that just won't quit. (2006) (17)
- A simple device to illustrate the Einthoven triangle. (2012) (17)
- Dual role of inorganic polyphosphate in cardiac myocytes: The importance of polyP chain length for energy metabolism and mPTP activation. (2019) (17)
- The force-frequency relationship: insights from mathematical modeling. (2013) (17)
- Calcium binding to cardiac sarcolemmal vesicles: potential role as a modifier of contraction. (1986) (17)
- Contractile activity modulates atrial natriuretic factor gene expression in neonatal rat ventricular myocytes. (1998) (17)
- Two-hit mechanism of cardiac arrhythmias in diabetic hyperglycemia: reduced repolarization reserve, neurohormonal stimulation and heart failure exacerbate susceptibility. (2021) (16)
- Cardiac pacemaking: I(f) vs. Ca(2+), is it really that simple? (2003) (16)
- Cardiac CaMKII activation promotes rapid translocation to its extra-dyadic targets. (2018) (16)
- Calcium-Dependent Arrhythmogenic Foci Created by Weakly Coupled Myocytes in the Failing Heart (2017) (16)
- Making and using calcium-selective mini- and microelectrodes. (2010) (16)
- Time course of action of antagonists of mitochondrial Ca uptake in intact ventricular myocytes (2002) (16)
- Depolarization of cardiac membrane potential synchronizes calcium sparks and waves in tissue. (2014) (16)
- Reduced Arrhythmia Inducibility With Calcium/Calmodulin-dependent Protein Kinase II Inhibition in Heart Failure Rabbits (2016) (15)
- Sources and Sinks of Activator Calcium (2001) (15)
- Nuclear translocation of calmodulin in pathological cardiac hypertrophy originates from ryanodine receptor bound calmodulin. (2018) (15)
- Translational medicine: To the rescue of the failing heart (2011) (15)
- Na/Ca Exchange and the Sarcolemmal Ca-Pump (2001) (15)
- How does β-adrenergic signalling affect the transitions from ventricular tachycardia to ventricular fibrillation? (2014) (15)
- Cardiac myocyte alternans in intact heart: Influence of cell-cell coupling and β-adrenergic stimulation. (2015) (15)
- Dynamic Imaging in Living Cells: Windows into Local Signaling (2003) (15)
- Citrate decreases contraction and Ca current in cardiac muscle independent of its buffering action. (1991) (14)
- CaMKII and PKA-dependent phosphorylation co-regulate nuclear localization of HDAC4 in adult cardiomyocytes (2021) (14)
- Optical Mapping of Sarcoplasmic Reticulum Ca2+ in the Intact HeartNovelty and Significance (2014) (14)
- Cardiac Calcium Channels (2004) (14)
- AKAP18δ Anchors and Regulates CaMKII Activity at Phospholamban-SERCA2 and RYR (2021) (13)
- CaMKII Serine 280 O-GlcNAcylation Links Diabetic Hyperglycemia to Proarrhythmia (2021) (13)
- JNK2, A Newly-Identified SERCA2 Enhancer, Augments an Arrhythmic [Ca2+]SR Leak-Load Relationship. (2020) (13)
- Ketone Ester D‐β‐Hydroxybutyrate‐(R)‐1,3 Butanediol Prevents Decline in Cardiac Function in Type 2 Diabetic Mice (2021) (12)
- Membrane receptor neighborhoods: snuggling up to the nucleus. (2013) (12)
- Junctional Cleft [Ca 2+ ] i Measurements Using Novel Cleft-Targeted Ca 2+ Sensors (2014) (12)
- Control of Cardiac Contraction by SR and Sarcolemmal Ca Fluxes (2001) (12)
- Inositol Trisphosphate Receptors and Nuclear Calcium in Atrial Fibrillation. (2020) (12)
- Harnessing the Power of Integrated Mitochondrial Biology and Physiology: A Special Report on the NHLBI Mitochondria in Heart Diseases Initiative. (2015) (12)
- Phospholamban overexpression in rabbit ventricular myocytes does not alter sarcoplasmic reticulum Ca transport. (2009) (12)
- Sarcoplasmic Reticulum Ca Uptake, Content and Release (1993) (11)
- Citrate alters Ca channel gating and selectivity in rabbit ventricular myocytes. (1992) (11)
- Digitalis and Na/Ca exchange: old dog learns new mitochondrial tricks. (2010) (11)
- Sodium and calcium regulation in cardiac myocytes: from molecules to heart failure and arrhythmia (2015) (11)
- Calmodulin and Ca 2+ /calmodulin kinases in the heart — Physiology and pathophysiology (2007) (11)
- Increasing SERCA function promotes initiation of calcium sparks and breakup of calcium waves (2021) (11)
- Empagliflozin Reverses Late Na+ Current Enhancement and Cardiomyocyte Proarrhythmia in a Translational Murine Model of Heart Failure With Preserved Ejection Fraction. (2022) (11)
- Balance Between Rapid Delayed Rectifier K+ Current and Late Na+ Current on Ventricular Repolarization (2020) (11)
- FRET-based trilateration of probes bound within functional ryanodine receptors. (2014) (10)
- A method to estimate mitochondrial Ca2+ uptake in intact cardiac myocytes. (1996) (10)
- Cardiac Action Potential and Ion Channels (2001) (10)
- Mechanoelectric coupling and arrhythmogenesis in cardiomyocytes contracting under mechanical afterload in a 3D viscoelastic hydrogel (2021) (10)
- Cardiotoxicity of environmental contaminant tributyltin involves myocyte oxidative stress and abnormal Ca2+ handling. (2019) (10)
- Subcellular localization of Na/K-ATPase isoforms in ventricular myocytes. (2017) (10)
- Differences in action potential configuration in ventricular trabeculae correlate with differences in density of transverse tubule-sarcoplasmic reticulum couplings. (1988) (9)
- Loss of CASK Accelerates Heart Failure Development (2021) (9)
- Reverse Mode of the Sarcoplasmic Reticulum Ca Pump Limits Sarcoplasmic Reticulum Ca Uptake in Permeabilized and Voltage‐Clamped Myocytes (1998) (9)
- Stabilizing ryanodine receptor gating quiets arrhythmogenic events in human heart failure and atrial fibrillation. (2017) (9)
- Role of Reduced Sarco-Endoplasmic Reticulum Ca2+-ATPase Function on Sarcoplasmic Reticulum Ca2+ Alternans in the Intact Rabbit Heart (2021) (9)
- α‐Actinin‐1 promotes activity of the L‐type Ca2+ channel Cav1.2 (2020) (9)
- Major Cellular Structures Involved in Excitation-Contraction Coupling (1993) (8)
- Influence of a constitutive increase in myofilament Ca(2+)-sensitivity on Ca(2+)-fluxes and contraction of mouse heart ventricular myocytes. (2014) (8)
- Sr Ca-pump and Na/Ca exchange in relaxation of rabbit ventricular muscle (1988) (8)
- Quantitative cross-species translators of cardiac myocyte electrophysiology: Model training, experimental validation, and applications (2020) (8)
- Measurement of calcium transport in heart using modern approaches. (1996) (8)
- Amylin and diabetic cardiomyopathy - amylin-induced sarcolemmal Ca2+ leak is independent of diabetic remodeling of myocardium. (2017) (8)
- Abstract 396: CaMKIIδ and PKD Overexpression seen in Heart Failure Maintains the HDAC5 Redistribution from the Nucleus to the Cytosol (2006) (8)
- 16 – Excitation–Contraction Coupling (2018) (8)
- Mechanical Load Regulates Excitation-Ca2+ Signaling-Contraction in Cardiomyocyte. (2021) (8)
- CaMKII comes of age in cardiac health and disease (2014) (8)
- Possible Sources and Sinks of Activator Calcium (1993) (7)
- Upregulation of Na 1 / Ca 2 1 Exchanger Expression and Function in an Arrhythmogenic Rabbit Model of Heart Failure (1999) (7)
- Simultaneous Measurement of [Na]i, [Ca]i, and INCX in Intact Cardiac Myocytes (2002) (7)
- Sinus Rhythm and Chronic Atrial Fibrillation (2011) (7)
- Monoamine Oxidases Desensitize Intracellular β1AR Signaling in Heart Failure. (2021) (7)
- Calcium Chelators and Calcium Ionophores (1988) (7)
- Human biological pacemakers: intrinsic variability and stability. (2012) (6)
- Derived Cardiomyocytes and Low-Impedance Microelectrode Arrays − Screening Drug-Induced Arrhythmia Using Human Induced Pluripotent Stem Cell (2013) (6)
- Calcium at the surface of cardiac plasma membrane vesicles: Cation binding, surface charge screening, and Na−Ca exchange (2005) (6)
- BayK 8644 increases resting calcium spark frequency in ferret ventricular myocytes. (1997) (6)
- Erratum: A mathematical treatment of integrated Ca dynamics within the ventricular myocyte (Biophysical Journal (2004) 87 (3351-3371)) (2012) (6)
- The role of Ca influx in cardiac muscle excitation-contraction coupling. Assessment by extracellular Ca microelectrodes. (1985) (6)
- Abstract 1157: Cardiac Consequences of Increased Amylin Secretion in Diabetics (2009) (6)
- L30A Mutation of Phospholemman Mimics Effects of Cardiac Glycosides in Isolated Cardiomyocytes. (2016) (5)
- Stretch-Activated Current Can Promote or Suppress Cardiac Alternans Depending on Voltage-Calcium Interaction. (2016) (5)
- α-Actinin-1 promotes activity of the L-type Ca2+ Channel CaV1.2 (2019) (5)
- Positive and negative effects of nitric oxide on Ca2+ sparks: influence of β-adrenergic stimulation : Nitric oxide-hormones, metabolism, and function (2001) (5)
- Normal and abnormal calcium homeostasis (2005) (5)
- Roles of Diastolic Leak and Ca Transport (2003) (5)
- Na(+) channel I-II loop mediates parallel genetic and phosphorylation-dependent gating changes. (2012) (5)
- Ca Influx Via Sarcolemmal Ca Channels (1993) (5)
- Measuring intranuclear and nuclear envelope [Ca(2+)] vs. cytosolic [Ca (2+)]. (2015) (5)
- Cardiac Inotropy and Ca Overload (1993) (4)
- Models of Human Atrial Action Potential for Sinus Rhythm and Chronic Atrial Fibrillation (2011) (4)
- Diabetic Hyperglycemia Regulates Potassium Channels and Arrhythmias in the Heart via Autonomous CaMKII Activation by O-Linked Glycosylation (2019) (4)
- Abstract 197: Overexpression of the Na+/K+ ATPase a2 But Not a1 Isoform Attenuates Pathological Cardiac Hypertrophy and Remodeling (2013) (4)
- Endurance training restores spatially distinct cardiac mitochondrial function and myocardial contractility in ovariectomized rats (2019) (4)
- Excitation-Contraction Coupling (2001) (4)
- Myofilaments: The End Effector of E-C Coupling (1993) (4)
- Smoking Gun or Red Herring (2012) (4)
- Subcellular Propagation of Cardiomyocyte β-Adrenergic Activation of Calcium Uptake Involves Internal β-Receptors and AKAP7 (2022) (4)
- Two different electrophysiological responses to ryanodine: evidence for two populations of muscles isolated from the rabbit right ventricle. (1987) (4)
- Divergent Regulation of Ryr2 Calcium Release Channels by Arrhythmogenic Human Calmodulin Missense Mutants (2014) (4)
- Calcium-sensitive mini- and microelectrodes. (2013) (4)
- Abstract 422: Ca/calmodulin Kinase II Differentially Modulates Transient Outward Potassium Current in Heart Failure (2006) (4)
- Na/K-ATpase α2-Subunit Preferentially Modulates Ca Transients and SR Ca Release in Cardiac Myocytes (2010) (3)
- Isoproterenol-Enhanced Diastolic Sarcoplasmic Reticulum Ca Leak in Ventricular Myocytes Requires Activation of Nitric Oxide Synthase (2009) (3)
- Confocal imaging of CICR events from isolated and immobilized SR vesicles. (2005) (3)
- Faculty Opinions recommendation of The C terminus of the L-type voltage-gated calcium channel Ca(V)1.2 encodes a transcription factor. (2007) (3)
- Binding of RyR2 “Unzipping” Peptide in Cardiomyocytes Activates RyR2 and Reciprocally Inhibits Calmodulin Binding (2012) (3)
- CALMing Down Arrhythmogenic Calmodulinopathies via a Precision Medicine Approach. (2017) (3)
- CaMKII Phosphorylation of NaV1.5: Novel in Vitro Sites Identified by Mass Spectrometry and Reduced S516 Phosphorylation in Human Heart Failure (2017) (3)
- Abstract 19557: Novel Stress Signaling JNK Regulates Pro-arrhythmic Molecular CaMKIIδ Activity and Expression in Aged Human Atrium (2014) (3)
- Contributions Sarcoplasmic Reticulum Ca 21 Uptake and Thapsigargin Sensitivity in Permeabilized Rabbit and Rat Ventricular Myocytes (2005) (3)
- Abstract 14157: Calmodulin Mutations in Human Genetic Arrhythmia Disorders Exhibit Divergent Functional Effects on Ryanodine Receptor Ca Release Channels (2013) (3)
- MarkoLAB: A simulator to study ionic channel's stochastic behavior (2017) (3)
- Functional remodelling of perinuclear mitochondria alters nucleoplasmic Ca2+ signalling in heart failure (2022) (3)
- Abstract 18345: Accumulation of Islet Amyloid Polypeptide Oligomers in the Heart in Type-2 Diabetes Alters Ca Cycling in Myocytes (2010) (2)
- Positive and negative effects of nitric oxide on Ca 2 1 sparks: influence of b -adrenergic stimulation (2001) (2)
- Isoform-specific Regulation Of The Ca-sensitive Transcription Factor NFAT In The Cardiovascular System (2009) (2)
- How to make calcium-sensitive microelectrodes. (2013) (2)
- Nitrosylation of cardiac CaMKII at Cys290 mediates mechanical afterload‐induced increases in Ca2+ transient and Ca2+ sparks (2022) (2)
- CaMKII in Cardiac Health and Disease (2014) (2)
- Anti-arrhythmic effects of interleukin-1 inhibition following myocardial infarction (2017) (2)
- The ratio of ryanodine:Dihydropyridine receptors (RYR:DHPR) in cardiac and skeletal muscle and implications for E-C coupling (1992) (2)
- CaMKIIδ post-translational modifications increase affinity for calmodulin inside cardiac ventricular myocytes (2021) (2)
- St slow force response in isolated rabbit myocardium (2003) (2)
- 110 Local β-adrenergic stimulation overcomes source-sink mismatch to generate focal arrhythmia (2012) (2)
- Calmodulin and S100A1 fine tune skeletal muscle E-C coupling. Focus on "Modulation of sarcoplasmic reticulum Ca2+ release in skeletal muscle expressing ryanodine receptor impaired in regulation by calmodulin and S100A1". (2011) (2)
- How to make calcium-sensitive minielectrodes. (2013) (2)
- Formation of Polyphosphate-Poly-Beta-Hydroxybutyrate Granule-Like Complexes in Heart Failure Myocytes (2016) (2)
- 32 – Models of the Ventricular Action Potential in Health and Disease (2013) (2)
- Cardiac myocyte calcium transport in phospholamban knockout mouse: relaxation and endogenous CaMKII effects. (1998) (2)
- In Situ Measurement of RyR2-Calmodulin Binding in Permeabilized Cardiomyocytes (2011) (2)
- I Na in animal models of hypertrophy and heart failure: contractile function and arrhythmogenesis (2003) (2)
- Beta-Adrenergic Activation Enhances Histone Deacetylase 4 nuclear Localization via Pka and Counters Camkii-Dependent Effects in Adult Rabbit Cardiac Myocytes (2011) (2)
- Protein Kinase D1 Regulates Cardiac Hypertrophy, Potassium Channel Remodeling, and Arrhythmias in Heart Failure (2022) (2)
- Measuring Local Gradients of Intra-Mitochondrial [Ca] in Cardiac Myocytes During SR Ca Release (2012) (2)
- Regulation of Cellular Calcium in Cardiac Myocytes (2011) (2)
- CHAPTER 44 – Inotropic Mechanisms in Cardiac Muscle (2001) (2)
- Mechanics and energetics in cardiac arrhythmias and heart failure (2020) (1)
- Teaching Basic Electrophysiology with the Aid of a Computer Program (2010) (1)
- Transsarcolemmal Ca movements in mammalian cardiac muscle monitored with extracellular Ca microelectrodes (1985) (1)
- Acknowledgment of Guest Editors, 2019 (2019) (1)
- 0144 QUANTIFICATION OF CAPACITANCE-VOLUME RATIO AND Ca^ FLUX IN CARDIAC MYOCYTES WITH LASER CONFOCAL MICROSCOPY AND WHOLE CELL PATCH-CLAMP TECHNIQUE (1997) (1)
- CaMKII and Heart Failure Promote a Pathological Ryanodine Receptor Conformation that Reduces Calmodulin Binding and Enhances SR Ca2+ Leak (2016) (1)
- Ca 2+ Release from the Sarcoplasmic Reticulum in Intact Cardiomyocytes (2005) (1)
- Iapp Preamyloid Oligomers Accumulate in the Heart and Contribute to Cardiac Dysfunction in Type-2 Diabetes (2010) (1)
- Beat-to-beat dynamic regulation of intracellular pH in cardiomyocytes (2021) (1)
- Abstract 243: Modeling of Diastolic Dysfunction in Induced Pluripotent Stem Cell-derived Cardiomyocytes From Hypertrophic Cardiomyopathy Patients (2018) (1)
- Calcium channels are ganging up in the sarcolemma. (2010) (1)
- Diversity and functional roles of K + channels in cardiac repolarization : from single cell to whole organ levels (2016) (1)
- Annual Review of Physiology 2014 (2014) (1)
- The late sodium current in heart failure: pathophysiology and clinical relevance: Late sodium current in heart failure (2014) (1)
- K+ channels and cardiac electrophysiology (2017) (1)
- PK11195 Protects From Cell Death Only When Applied During Reperfusion: Succinate-Mediated Mechanism of Action (2021) (1)
- Changes in Ca2+/Calmodulin-Dependent Protein Kinase (CaMKII) During Development of Hypertension-Induced Hypertrophy and Heart Failure (2011) (1)
- Abstract 12383: Phosphomimetic Mutations Enhance FXYD1 (Phospholemman) Oligomerization and Reduce Its Interaction with the Na/K-ATPase in Live Cells (2010) (1)
- Recording and Measurement of Action Potentials (2013) (1)
- The response of cardiac muscle to stretch: calcium and force (2011) (1)
- Cardiac ryanodine receptor N-terminal region biosensors identify novel inhibitors via FRET-based high-throughput screening (2021) (1)
- 16 – Excitation-Contraction Coupling (2014) (1)
- Minding the store of Ca2+ during ischaemia/reperfusion. (2010) (1)
- Rabbit Ventricular Myocytes Gradients During Excitation-Contraction Coupling in Newborni ] 2 + Subcellular (1999) (1)
- Stretch Activated Channel Activation can Promote or Suppress Cardiac Alternans (2015) (1)
- Spatiotemporal Control of Vascular CaV1.2 by α1C S1928 Phosphorylation (2022) (1)
- Abstract 20245: Specific Intracellular Glycosylation Directly Modulates CaMKII Activity During Hyperglycemia (2010) (1)
- Correction for Feng et al., Constitutive BDNF/TrkB signaling is required for normal cardiac contraction and relaxation (2015) (1)
- Sex Differences Of RyR2 Expression And Phosphorylation In Heart Failure (2009) (1)
- FRET Detection of CaM-RyR2 Binding Modulation by S100A1 (2013) (1)
- Whole-heart multiparametric optical imaging reveals sex-dependent heterogeneity in cAMP signaling and repolarization kinetics (2023) (1)
- Adrenergic Fight-or-Flight: S-NO Falls on PKA Targets. (2015) (1)
- Ca flux, contractility, and excitation-contraction coupling in hypertrophic rat ventricular myocytes. (1998) (1)
- Local Depletions of Free [Ca 2 (cid:1) ] in Cardiac Sarcoplasmic Reticulum During Contractions Leave Substantial Ca 2 (cid:1) Reserve (2003) (1)
- Na+ channel regulation, structure, trafficking and sequestration (2015) (1)
- Citrate decreases Ca current and changes selectivity of cardiac Ca channels. (1992) (1)
- Cytosolic Ca-Dependent Na/Ca Exchange Regulation in Intact Cardiomyocytes: Role of Cytosolic Na (2010) (1)
- Post-translational Modifications of the Cardiac Na Channel 1 Contribution of CaMKII-Dependent Phosphorylation to Acquired 2 Arrhythmias 3 4 5 6 (2013) (1)
- Differential distribution of mouse cardiac Na/K ATPase alpha(1) and alpha(2)-subunit function in T-tubule and surface sarcolemmal membranes (2006) (1)
- Epac 2 Mediates Cardiac 1-Adrenergic Dependent SR Ca 2 + Leak and Arrhythmia Running title : (2013) (1)
- Emerging Role of the Mitochondrial Outer Membrane Translocator Protein (TSPO) in Heart Failure and Mitochondrai Quality Control (2017) (1)
- FRET-Based Trilateration of a Domain Peptide Bound within Functional Ryanodine Receptors in Cardiomyocytes (2014) (1)
- Abstract 802: Dynamic FRET-Based Ca-Calmodulin Measurements in Intact Ventricular Myocytes Uncover Differential Signal Integration Due to Ca-Calmodulin Affinity (2007) (1)
- Ketone Bodies and their Polymers in Heart Failure and Type 2 Diabetes: Lessons Learned from the Ketone Ester Diet (2019) (1)
- Calcium influx and sarcoplasmic reticulum calcium release in cardiac excitation-contraction coupling (1987) (1)
- Sudden unexpected death (2005) (1)
- Myocyte Nitric Oxide Synthase 2 Contributes to Blunted (cid:1) -Adrenergic Response in Failing Human Hearts by Decreasing Ca 2 (cid:2) Transients (2004) (0)
- Cell Edge Detector: Recovering Length Information from Line-Scan Confocal Images (2013) (0)
- FKBP12.6 Inhibits Resting Ryanodine Receptor Activity but PKA-Dependent Phosphorylation Does Not Alter FKBP12.6-RyR2 Binding in Rat Permeabilized Myocytes (2010) (0)
- Abstract 198: Endothelin-1 and Phenylephrine Activate Global Protein Kinase D Similarly in Adult Cardiac Myocytes, but Differ Greatly in Nuclear versus Sarcolemmal Targeting (2007) (0)
- Computer Simulation of Altered Sodium Channel Gating in Rabbit and HumanVentricular Myocytes (2007) (0)
- Nitric Oxide Can Mediate Beta-Adrenergic- and CaMKII-Dependent Spontaneous Ca2+ Waves in Cardiac Myocytes, Independent of PKA Activation (2010) (0)
- Expression in Cultured Neonatal Rat Heart Cells (2005) (0)
- Faculty Opinions recommendation of Pacing-induced heterogeneities in intracellular Ca2+ signaling, cardiac alternans, and ventricular arrhythmias in intact rat heart. (2006) (0)
- Increased SR Calcium Leak is Promoted by O-GlcNAcylation of CaMKII in Diabetes and Hyperglycemia (2020) (0)
- Dysregulation of intracellular pH in the failing heart. (2023) (0)
- Neuron-Restrictive Silencer Factor Limits Myocyte GαO Expression and Is Protective in Heart Failure Progression. (2022) (0)
- In Silico Assessment of the Effect of Ca-Calmodulin Dependent Protein Kinase II (CaMKII) on Rabbit Ventricular Ion Currents and Action Potential (2007) (0)
- Modeling of the Small-Conductance Calcium-Activated Potassium Channel and Cardiac Alternans (2016) (0)
- Pkd1 is necessary for full cardiac AngII-induced hypertrophy but not for full acute AngII-induced calcium handling changes. (2023) (0)
- Diminished β-Adrenergic Response in Protein Kinase D Knock-Out Cardiomyocytes (2020) (0)
- P119Changes of the late sodium current and the inward rectifier potassium current can contribute to generation of arrhythmias in heart failure (2014) (0)
- Faculty Opinions recommendation of Synergy between CaMKII substrates and β-adrenergic signaling in regulation of cardiac myocyte Ca(2+) handling. (2010) (0)
- Na Pump E960 Site is Critical for the Interaction with Phospholemman (2011) (0)
- CaMKII Regulates Cardiac Sodium Channel Nav1.5 by Phosphorylation in the Loop Between Domain I and II (2011) (0)
- Intrinsically Disordered Islet Amyloid Polypeptide Is a Pathogenic Link Between Type-2 diabetes and Heart Disease (2011) (0)
- Increased Ca Sparks and Waves Frequency and Unchanged [Na]i in Hearts from Ankyrin-B Heterozygous Mice (2010) (0)
- Endothelin and Phenylephrine Both Trigger Nuclear IP3 Elevation, but Differ in Ability to Activate Nuclear HDAC5 Export (2010) (0)
- Ca transport from the cytoplasm and dynamic cellular Ca balance in cardiac myocytes (1996) (0)
- Wednesday, 29 August 2012 (2012) (0)
- Ionic Current Changes during Action Potentials in Porcine Post-MI Heart Failure Model (2017) (0)
- Autoregulation of excitation-Ca2+ signaling-contraction and arrhythmogenesisin cardiomyocyte under mechanical load. (2023) (0)
- FRET assays for RyR-targeted drug discovery platforms (2022) (0)
- Assessing GPCR and G protein signaling to the nucleus in live cells using fluorescent biosensors. (2015) (0)
- Brain‐derived Neurotrophic Factor (BDNF) Directly Modulates Cardiac Ventricular Myocyte Function (2011) (0)
- CaMKIId As a Nodal Mediator of Insulin Signaling and Adrenergic Signaling in Cardiomyocytes – a Signaling Network Map Profiling by Quantitative Phospho‐proteomics (2016) (0)
- High-throughput Screening Yields Allosteric Inhibitors of Leaky RyRS for Therapeutic Applications (2018) (0)
- Phosphomimetic Mutations Increase FXYD1 Oligomerization, but Does Not Alter its Quaternary Conformation (2010) (0)
- Ca SR Leak is Modulated by CaMKII Phosphorylation on RyR2-S2814 (2010) (0)
- Dynamic Regulation of Intracellular PH in the Heart (2021) (0)
- Transitions Among Excitable, Oscillatory and Non-Excitable in Simplified Calcium Cycling Model (2012) (0)
- Arrhythmogenesis and Contractile Dysfunction in Heart Failure Roles of Sodium-Calcium Exchange, Inward Rectifier Potassium Current, and Residual b -Adrenergic Responsiveness Cellular Biology (2001) (0)
- Platform BA: Calcium Signaling Pathways (2009) (0)
- P21-2 - Protein Kinase a Activation Reduces Calmodulin-Ryanodine Affinity in R176Q/+ and R2474S/+ Knock-in Mouse (2017) (0)
- High-Throughput Screening and Drug Development to Fix RyR Pathology (2021) (0)
- IS042 FUNCTIONAL LINKAGE BETWEEN SARCOLEMMAL AND SR Ca CHANNELS : PARMACOLOGICAL MODULATION OF Ca SPARKS IN FERRET VENTRICULAR MYOCYTES (1997) (0)
- Ontogeny, ryanodine receptor‐mediated calcium sparks, and BK channel clustering in basilar arterial myocytes from long‐term hypoxic sheep (853.9) (2014) (0)
- Mechano-chemo-transduction is attenuated in a rabbit model of heart failure (2017) (0)
- Diabetes and Excess Aldosterone Promote Heart Failure With Preserved Ejection Fraction (2022) (0)
- The PLM Homotetramer has a Structural Basis that Parallels that of PLB: The Leucine Zipper (2013) (0)
- Epac2 Mediates Cardiac (cid:533) 1 -Adrenergic Dependent SR Ca 2+ Leak and Arrhythmia (2013) (0)
- Post-Translational Modifications Promote Functional Heterogeneity in Cardiac Myocytes (2021) (0)
- Ca++T LAB - A Computational Model for Intracellular Calcium Signaling In T Lymphocytes (2009) (0)
- In Failing Cardiomyocytes, CaM-RyR2 Dissociation Leads to Defective Domain Interaction and Channel Destabilization (2014) (0)
- Phospholamban Ablation Rescues SR Ca2+ Loading But Not Cardiac Function In CaMKIIλC Transgenic Mice (2006) (0)
- Tributytin Induces Negative Inotropic Effect, Reduces Cardiac SR Calcium Content and Increases Calcium Sparks Frequency in Cardiomyocytes (2018) (0)
- Coupling of the contraction and intracellular phin cardiomyocytes (2022) (0)
- MarkoLAB: A Graphical Interface To Study Stochastic Channel Behavior (2009) (0)
- FRET-Based Mapping of Calmodulin within the Ryanodine Receptor (2016) (0)
- Dual optical mapping of the innervated mouse heart reveals unique electrophysiological responses during fight-or-flight (2018) (0)
- Phospholamban Ablation Rescues SR Ca2+ Loading But Not Cardiac Function In CaMKII{lambda}C Transgenic Mice (2006) (0)
- Abstract 58: Modeling Pathogenesis in Familial Hypertrophic Cardiomyopathy Using Patient-Specific Induced Pluripotent Stem Cells (2012) (0)
- Diversity of Cells and Signals in the Cardiovascular System. (2023) (0)
- Dynamic Late Na Current During Cardiac Action Potential Revealed by a Specific and Potent Inhibitor Gs967 (2014) (0)
- SPARC: Found in translation: quantitative predictors of cardiac myocyte responses to β‐adrenergic stimulation across species (2020) (0)
- Autoregulation of excitation-Ca2+ signaling-contraction in cardiomyocyte under mechanical load (2022) (0)
- An Improved Model of Voltage- and Ca-Dependent Inactivation of the L-Type Ca Channels (2011) (0)
- Cardiac CaMKIIδ Memory: Post-Translational Modification-Mediated Prolongation of CaMKIIδ in Autonomously Active Open State (2020) (0)
- Faculty Opinions recommendation of Constitutively active phosphatase inhibitor-1 improves cardiac contractility in young mice but is deleterious after catecholaminergic stress and with aging. (2010) (0)
- RyR(R4496C) Mutant Mice Model Reveals a New Paradigm on Local Ca2+ Control of ICaL (2011) (0)
- Cardiac Na/Ca Exchange Suppression: A Late‐Breaking Knockout Story Showing That There Is No Free Lunch (2021) (0)
- Barbagallo et al β AR Signal on the Myofilaments in Heart Failure 933 AKAR 3 CFP FHA PKA substrate YFP CFP FHA PKA substrate YFP CFP FHA PKA (2016) (0)
- Abstract 356: CaMKII Cytoplasmic and Nuclear Isoforms Differentially Affect Calcium Handling but Similarly Regulate HDAC/MEF2 Transcriptional Responses (2006) (0)
- Effects of L‐type Ca2+ Channel Facilitation on Ca2+ Spark Activity in Fetal Ovine Pulmonary Arterial Myocytes (2015) (0)
- In vitro and in silico analysis of sodium-dependent regulation of mitochondrial calcium concentration and production of reactive oxygen species in rabbit ventricular myocytes (2022) (0)
- Chloride Transport Inhibition Causes Calcium-Dependent Arrhythmic Activity in Isoproterenol-Treated Rabbit Cardiomyocytes (2014) (0)
- UC Davis Cardiovascular Symposium 2014 Systems Approach to Understanding Cardiac Excitation-Contraction Coupling and Arrhythmias — Na + channel and Na + transport (2014) (0)
- Functional remodeling of perinuclear mitochondria alters nucleoplasmic Ca2+signaling in heart failure (2022) (0)
- Ion Channels of the Heart (2015) (0)
- Cellular Reactive Oxygen Species–Activated Ca/Calmodulin Kinase II (cid:1) Is Required for Late I Na Augmentation Leading to Cellular Na and Ca Overload (2011) (0)
- Abstract 581: Hyperglycemia Acutely Increases Cytosolic Reactive Oxygen Species (ROS) via O-linked GlcNAcylation Activation of CaMKII in Mouse Ventricular Myocytes (2019) (0)
- Intermittent Early Afterdepolarizations Caused by Bistability (2014) (0)
- in Humans and Rats Hyperamylinemia Contributes to Cardiac Dysfunction in Obesity and Diabetes : A Study (2012) (0)
- Point/counterpoint: a new feature in the JMCC. (2008) (0)
- Arrhythmogenic Crosstalk of Sodium, Calcium, Reactive Oxygen Species and Camkii Signaling in the Failing Rabbit Ventricular Myocyte - Insights from a Computational Study (2021) (0)
- Some just can't say enough in the new JMCC Point-Counterpoint feature. (2009) (0)
- Contributors to Volume 4 (1991) (0)
- The (cid:1) C Isoform of CaMKII Is Activated in Cardiac Hypertrophy and Induces Dilated Cardiomyopathy and Heart Failure (2003) (0)
- Superinhibitory Phospholemman Mutants as Potential Therapeutics for Heart Failure (2013) (0)
- Empagliflozin prevents oxidative stress induced by acute hyperglycemia in cardiac myocytes. (2023) (0)
- Sex differences in repolarization and slow delayed rectifier potassium current and their regulation by sympathetic stimulation in rabbits (2012) (0)
- High-Throughput Screens to Discover Inhibitors of Leaky Ryanodine Receptor Calcium Channels (2016) (0)
- Leak-Load Relationship 2 + Quantitative Assessment of the SR Ca (2002) (0)
- In Silico Studies of Cardiac Inotropy using a New Model of Force Generation (2010) (0)
- A Novel Fluorescent Epac-Agonist Reveals Epac1 and Epac2 Subcellular Localization in Cardiomyocytes (2014) (0)
- Cardiac Ca2+ current is ‘Rad’-ically altered by adrenergic activation (2022) (0)
- adenovirusof phospholamban with use of Functional alterations in adult rat myocytes after (2015) (0)
- Depolarization of Cardiac Membrane Potential Promotes Calcium Waves (2014) (0)
- A new Mathematical Formulation of the Plasma Membrane Ca2+-Atpase (PMCA) Provides Stability to Simulated Ca2+ Signaling in Human T Cells (2011) (0)
- Chronic SR Ca 2 (cid:1) -ATPase Inhibition Causes Adaptive Changes in Cellular Ca 2 (cid:1) Transport (2003) (0)
- Competition of Ca transporters in relaxation of rabbit ventricular myocytes and Ca redistribution from mitochondria to SR during rest (1992) (0)
- Voltage Dependence of Cardiac Excitation–Contraction Coupling Current Amplitude and Open Channel Probability (2007) (0)
- FRET-based trilateration resolves distinct structural states and transitions of calmodulin bound to ryanodine receptors (2022) (0)
- Stoichiometry: A discussion (2002) (0)
- FRET-Based Trilateration Resolves Distinct Structural States and Transitions of Calmodulin Bound to RyR (2019) (0)
- Calcium signaling in heart: multiscale, diverse, rapid, local, and remarkable. (2013) (0)
- GPCR Stimulation Modulates Camkii Translocation and Targeting in Cardiomyocytes (2020) (0)
- Calcium Regulation in Cardiac Myocytes: Systolic Dysfunction and Arrhythmogenesis in Heart Failure (2006) (0)
- High-Throughput Screening Yields Allosteric Inhibitors of Leaky RyRs for Therapeutic Development (2019) (0)
- Contribution of Calcium Waves to the Regulation of Beating Rhythm in Sinoatrial Node Cells (2012) (0)
- Abstract 12587: Telomere Length Regulates Cellular Fate of Cardiac Progenitor Cells (2015) (0)
- (cid:1) -Adrenergic Enhancement of Sarcoplasmic Reticulum Calcium Leak in Cardiac Myocytes Is Mediated by Calcium/Calmodulin-Dependent Protein Kinase (2007) (0)
- Cardiac-specific Conditional Knockout of the 18-kDa Mitochondrial Translocator Protein Protects from Induced Failure. (2018) (0)
- Pulmonary Arterial Hypertension (2007) (0)
- FRET-Based RyR-Selective Detection Reveals No Significant Competition between CaM and S100A1 Binding to RyRs (2015) (0)
- in hypertrophic rat ventricular myocytes Ca flux, contractility, and excitation-contraction coupling (2016) (0)
- Initiation and maintenance of arrhythmogenic action potential waves near the infarct zone in heart failure (2022) (0)
- Fluorescence-Labeled Imperacalcin Binds to Open RyR2 Channels in Mouse Ventricular Myocytes (2016) (0)
- Mapping the Site of RyR2 “Unzipping” Peptide (DPc10) by using Fluorescence Resonance Energy Transfer (FRET) in Permeabilized Cardiomyocytes (2012) (0)
- Localized Nitric Oxide Signaling Mediates Cardiac Mechano-Chemotransduction (2014) (0)
- Nitrosylation of cardiac CaMKII at Cys290 mediates mechanical-afterload induced increase in CA transients (2022) (0)
- Functional Modulation of Cardiac ATP-Sensitive Potassium Channels by Nitric Oxide via Intracellular Signaling (2013) (0)
- Mechano-Chemo-Transduction in Rabbit Cardiomyocytes Mediated by no Signaling (2016) (0)
- Structure Transitions of the Sodium, Potassium-ATPase Investigated by Intramolecular FRET (2013) (0)
- FRET Detection of RyR2 Calmodulin Binding and Calcium-Dependent Modulation by RyR22460-2495 Peptide (DPc10) (2012) (0)
- Sparklab2: A Statistically Based Program to Detect 2D Sparks. Application to Smooth Muscle (2014) (0)
- Diastolic Sodium Current in Cardiomyocytes Assessed with Lithium (2020) (0)
- Faculty Opinions recommendation of Flecainide prevents catecholaminergic polymorphic ventricular tachycardia in mice and humans. (2009) (0)
- Epac2 O-GlcNAcylation, a new player in high glucose-mediated cardiac calcium mishandling (2020) (0)
- Abstract 12006: Patients with Obesity and Type-2 Diabetes Present Cardiac IAPP Accumulation: A Source of Cardiomyocyte Ca2+ Dysregulation (2011) (0)
- FRET-Based Mapping and Millisecond Structural Kinetics of Calmodulin Bound to Ryanodine Receptor Channels (2018) (0)
- Cardiac protein kinase D1 ablation alters the myocytes β-adrenergic response (2023) (0)
- Abstract 20651: Ankyrin-B (+/-) Mice show Enhanced Sarcoplasmic Reticulum Ca Release in Cardiac Myocytes due to Altered Local Ca Concentration Regulation (2010) (0)
- Abstract 16963: Pre-Diabetes Promotes Buildup of Amylin in the Heart That Alters Cardiac Function by Remodeling the Myocytes (2012) (0)
- How Does RyR2-Mediated SR Calcium Leak Fail to Cause Sparks? (2011) (0)
- Calcium Signals Alter the Mobility and Localization of CaMKIIδ in Cardiomyocytes (2017) (0)
- Cardiac CAMKIIδ Memory: How Post-Translational-Modifications Alter Calmodulin Affinity (2020) (0)
- Transient Mitochondrial Permeability Transition Pore Opening in Cardiac Myocytes During SR Ca Release (2014) (0)
- Cardiac Action Potential Model with Spatial Subcellular Calcium Cycling and Physiological Transmembrane Currents (2010) (0)
- Quantitative Cross-Species Prediction of β-Adrenergic Response in Ventricular Myocytes (2020) (0)
- Oxidative Stress and Ca2+ Sparks in Pulmonary Arterial Myocytes of High Altitude Acclimatized Sheep (2015) (0)
- Initiation of calcium waves in failing cardiac myocytes is sensitive to posttranslational modifications (2022) (0)
- Channel Remodeling in Hyperglycemia and Diabetes Mellitus + -activated K 2+ Akap150 Contributes to Enhanced Vascular Tone by Facilitating Large-conductance Ca (2014) (0)
- A new software for detection of calcium sparks in cardiac myocytes (2022) (0)
- Ca21 Uptake and Thapsigargin Sensitivity in Permeabilized Rabbit and Rat Ventricular Myocytes (2005) (0)
- Correlative super‐resolution light microscopy and electron microscopy determines spatial Ryanodine receptor type 2 distribution in mouse ventricular myocytes (LB707) (2014) (0)
- Bers Attributable to Enhanced Sarcoplasmic Reticulum Ca Load-Adrenergic Stimulation in the Failing Heart Are 2 β Arrhythmogenic Effects of (2008) (0)
- S tretch-dependent slow force response in isolated rabbit myocardium 1 is Na dependent (2003) (0)
- Action Potential Duration Adaptation and Reverse-Rate Dependency in Human Ventricular Myocytes: Insights from a Computer Model (2010) (0)
- University of Birmingham Nitric oxide regulates cardiac intracellular Na and Ca² by modulating Na/K ATPase via PKC and phospholemman-dependent mechanism (2013) (0)
- Empagliflozin and ROS-CaMKII-late sodium current signaling in heart failure with preserved ejection fraction. (2023) (0)
- handling in isolated rat myocardium 2+ Effects of left ventricular hypertrophy on force and Ca (2016) (0)
- Measurement of Calcium Flux and Intracellular Sodium by Ion-Selective Microelectrodes (1991) (0)
- Inhibition of hsp27 Phosphorylation Increases Interaction with Hic5 in Vascular Myocytes (2008) (0)
- Calcium Fluxes and Homeostasis (2012) (0)
- Acute Hypoxia and Ryanodine Receptor Activity in Pulmonary Arterial Myocytes of High Altitude Acclimatized Fetal and Adult Sheep (2015) (0)
- Faculty Opinions recommendation of Carvedilol and its new analogs suppress arrhythmogenic store overload-induced Ca2+ release. (2011) (0)
- Role of Epac2 in High Glucose-Induced SR Ca 2+ Leak and Arrhythmia (2018) (0)
- Faculty Opinions recommendation of The cAMP binding protein Epac modulates Ca2+ sparks by a Ca2+/calmodulin kinase signalling pathway in rat cardiac myocytes. (2007) (0)
- Cardiac-specific Conditional Knockout of the 18-kDa Mitochondrial Translocator Protein Protects from Pressure Overload Induced Heart Failure (2018) (0)
- High Diastolic Sodium Influx in Heart Failure has Drug-Sensitivities Like Late Sodium Current, but Produces Inward Current at Diastolic Potentials (2017) (0)
- IP3 Receptor-mediated Ca Release Facilitates RyR-Ca Release To Cause Inotropy And Arrhythmogenicity In Mouse Ventricular Myocytes (2009) (0)
- Acknowledgment of Reviewers, 2019 (2019) (0)
- Integrative Physiology Hyperamylinemia Contributes to Cardiac Dysfunction in Obesity and Diabetes A Study in Humans and Rats (2012) (0)
- Abstract 20480: Channel Pore Mutation of RyR2 Cause Calcium Leak Independent of FKBP12.6-RyR2 and Calmodulin-RyR2 Affinity in R4496C/+ Knock-in Mouse (2017) (0)
- 052Dual optical mapping of the innervated Langendorff-perfused heart reveals novel insights into acute electrophysiological responses to sympathetic stimulation (2017) (0)
- Erratum: (Biophysical Journal) (2011) (0)
- Abstract 12222: Cardiomyocyte Ryanodine Receptor Oxidation in Situ Causes Defective Interdomain Interaction and Reduces Calmodulin Binding (2013) (0)
- Results Transient PTP Openings in Single Mitochondria During Cyclic Sarcoplasmic Reticulum Ca (2016) (0)
- Mitochondrial Translocator Protein (TSPO) Prevents Heart Failure by Increasing Cardiac Utilization of Fatty Acids (2020) (0)
- Ca21 Content of Rabbit Ventricular Muscle (2005) (0)
- Excessive Sarcoplasmic/Endoplasmic Reticulum Ca 2 (cid:1) -ATPase Expression Causes Increased Sarcoplasmic Reticulum Ca 2 (cid:1) Uptake but Decreases Myocyte Shortening (2004) (0)
- Correction (1959) (0)
- Synergistic FRET assays for drug discovery targeting RyR2 channels (2022) (0)
- Advancing cardiac safety with a “thorough preclinical QT Study” using low-impedance microelectrode arrays and human stem cell-derived cardiomyocytes (2014) (0)
- Akt regulates L-type Ca 2+ channel activity by modulating Ca v (cid:2) 1 protein stability (2009) (0)
- Protein kinase D1 is required for full β-adrenergic effects on cardiac calcium handling, but not under chronic stress (2022) (0)
- Reduced Ca Flux via Ryanodine Receptor Cluster Size or Unitary Current can both Promote Long-Lasting Ca Sparks (2015) (0)
- In Failing Cardiomyocytes, Calmodulin Dissociation From RYR2 and Defective Domain Interaction Leads To Channel Destabilization (2014) (0)
- Abstract 14468: Atrial Fibrillation-Related Nuclear Calcium Remodeling and Transcriptional Signaling (2016) (0)
- Visualizing CaMKII and CaM activity: a paradigm of compartmentalized signaling (2013) (0)
- Release Measuring Local Gradients of Intra-Mitochondrial [ Ca ] in Cardiac Myocytes During SR Ca (2012) (0)
- Modeling the human ventricular myocyte (2004) (0)
- Feed Forward Modeling. Fixing the Force Frequency Relationship (2012) (0)
- CaMKII-Dependent Phosphorylation of RyR2 Causes Domain Unzipping and Reduced Calmodulin Binding, But Dantrolene Reverses These Effects (2015) (0)
- Abstract 495: Ryanodine Receptor Phosphorylation in Intact Rat Ventricular Cardiomyocytes: Caution with Phosphorylation Site-Specific Antibodies (2007) (0)
- Role of Epac2 in high glucose induced SR Ca 2+ leak and arrhythmia (2018) (0)
- Diabetic Hyperglycemia Acutely Affects Action Potentials and Ionic Currents through CaMKII Activation on Rat Ventricular Myocytes (2014) (0)
- Post-translational modification-dependent regulation of CaMKII-delta conformation in live cardiac myocytes. (2023) (0)
- Regulation of SR Calcium Release in Intact Ventricular Myocytes (1998) (0)
- New Cardiac Targets for Empagliflozin: O-GlcNAcylation, CaMKII, and Calcium Handling. (2023) (0)
- Preservation of Ca2+ spark activity during oxidative stress in pulmonary arterial myocytes of fetal sheep (1089.5) (2014) (0)
- High-Throughput Screens to Discover Inhibitors of Leaky Ryanodine (2017) (0)
- Ranolazine Prevents Phase-3 Early Afterdepolarizations in Human Atrial Myocytes by Inhibiting Na Current Non-Equilibrium Reactivation (2015) (0)
- Na 1 / K 1-ATPase a 2-isoform preferentially modulates Ca 2 1 transients and sarcoplasmic reticulum Ca 2 1 release in cardiac myocytes (2012) (0)
- Suppression of Cardiac L-Type Ca Channel Activity Causes Cardiac Hypertrophy (2011) (0)
- Faculty Opinions recommendation of X-ROS signaling: rapid mechano-chemo transduction in heart. (2012) (0)
- Mg2+ Inhibits Cardiac SR Calcium Release and has Biphasic Effects on Calmodulin Binding to RyR2 (2017) (0)
- O‐GlcNAcylation of CaMKII in Cardiac Myocytes can be Pro‐Arrhythmic (2015) (0)
- S-nitrosylation of CaMKII cys273 suppresses CaMKII activation and translocation within cardiac myocytes. (2023) (0)
- Kinetics and mapping of calcium-driven calmodulin conformations on ryanodine receptors. (2023) (0)
- Intracellular Calcium Alters IKs Amplitude and Kinetics in Rabbit Myocytes (2015) (0)
- Regulation of beige adipocyte thermogenesis by the cold-repressed ER protein NNAT (2023) (0)
- ltered Myocardial Ca 2 Cycling fter Left Ventricular Assist Device upport in the Failing Human Heart (2016) (0)
- Quantitative In Silico Analysis of the Arrhythmogenic CaMKII-Sodium-Calcium-CaMKII Feedback in the Failing Rabbit Ventricular Myocyte (2019) (0)
- The Role of Cysteine 3602 in RyR2 Regulation by Calmodulin and Oxidative Stress (2019) (0)
- Abstract 18460: Nuclear Translocation of Calmodulin, Which Dissociated From Cardiac Ryanodine Receptor, Promotes the Pathological Cardiac Hypertrophy (2016) (0)
- Abstract 16535: Conditional Knockout of the Mitochondrial 18-kDa Translocator Protein Limits Heart Failure (2015) (0)
- Ca-calmodulin signaling in the heart, in health and disease (2016) (0)
- O-Glycosylation of Camkii at Serine 280 Promotes Cardiac Arrhythmias in Diabetic Hyperglycemia (2020) (0)
- Identification of Phospholemman Residues Critical to Phospholemman Oligomerization and Na Pump Association (2011) (0)
- Beta-Adrenergic Signaling in Isolated Cardiomyocytes Propagates Spatially Over Time (2020) (0)
- Disruption of sodium homeostasis in cardiac disease In the session on ‘ Disruption of Na + homeostasis (2015) (0)
- Fixing a current problem in the cardiac Na channel (2022) (0)
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What Schools Are Affiliated With Donald M. Bers?
Donald M. Bers is affiliated with the following schools:
- University of California, Riverside
- Rockefeller University
- Wuhan University of Science and Technology
- Rush University
- Sapienza University of Rome
- University of Manchester
- King's College London
- Medical University of Graz
- University of Colorado Boulder
- University of Cincinnati
- University of California, San Diego
- State University of Campinas
- University of California, Los Angeles
- University of California, Davis
- University System of Maryland
- Baylor College of Medicine
- Loyola University Chicago
- University of Glasgow
- University of California, San Francisco
- New York University
- Ohio State University
- University of Minnesota