Donna E. Davies

Q: What Schools Are Affiliated With Donna E. Davies

Donna E. Davies is affiliated with the following schools: Imperial College London, University of Oxford, University of Southampton

Donna E. Davies's AcademicInfluence.com Rankings

Donna E. Davies

Biology

#11104

World Rank

#14479

Historical Rank

Biochemistry

#2199

World Rank

#2344

Historical Rank

biology Degrees

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Biology

Donna E. Davies's Degrees

Bachelors Chemistry University of Oxford

Why Is Donna E. Davies Influential?

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According to Wikipedia, Donna Elizabeth Davies is a British biochemist and professor of respiratory cell and molecular biology at the University of Southampton. In 2003, Davies was the co-founder of Synairgen, an interferon-beta drug designed to treat patients with asthma and chronic obstructive pulmonary disease.

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Donna E. Davies's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Asthmatic bronchial epithelial cells have a deficient innate immune response to infection with rhinovirus (2005) (1011)
Role of deficient type III interferon-λ production in asthma exacerbations (2006) (879)
Role of deficient type III interferon-lambda production in asthma exacerbations. (2006) (613)
Epithelial-mesenchymal interactions in the pathogenesis of asthma. (2000) (559)
Airway remodeling in asthma: new insights. (2003) (536)
Involvement of the epidermal growth factor receptor in epithelial repair in asthma (2000) (528)
Defective epithelial barrier function in asthma. (2011) (520)
Tumour necrosis factor (TNFα) as a novel therapeutic target in symptomatic corticosteroid dependent asthma (2005) (484)
A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations (2013) (478)
Leukocyte analysis and differentiation using high speed microfluidic single cell impedance cytometry. (2009) (390)
Oxidative stress–induced mitochondrial dysfunction drives inflammation and airway smooth muscle remodeling in patients with chronic obstructive pulmonary disease (2015) (299)
Effect of bronchoconstriction on airway remodeling in asthma. (2011) (284)
The contribution of interleukin (IL)-4 and IL-13 to the epithelial-mesenchymal trophic unit in asthma. (2001) (274)
Relationship between peripheral airway dysfunction, airway obstruction, and neutrophilic inflammation in COPD (2004) (258)
The contribution of transforming growth factor-β and epidermal growth factor signalling to airway remodelling in chronic asthma (2006) (251)
Safety and efficacy of inhaled nebulised interferon beta-1a (SNG001) for treatment of SARS-CoV-2 infection: a randomised, double-blind, placebo-controlled, phase 2 trial (2020) (231)
Epithelial-mesenchymal communication in the pathogenesis of chronic asthma. (2004) (229)
The effect of inhaled IFN-β on worsening of asthma symptoms caused by viral infections. A randomized trial. (2014) (219)
A new look at the pathogenesis of asthma (2009) (208)
Cooperative Effects of Th2 Cytokines and Allergen on Normal and Asthmatic Bronchial Epithelial Cells1 (2002) (207)
Expression of genes involved in oxidative stress responses in airway epithelial cells of smokers with chronic obstructive pulmonary disease. (2007) (203)
The role of the airway epithelium and its interaction with environmental factors in asthma pathogenesis. (2009) (200)
The role of the epithelium in airway remodeling in asthma. (2009) (199)
Epithelial stress and structural remodelling in childhood asthma (2005) (197)
Analysis of novel disease-related genes in bronchial asthma. (2002) (194)
The role of a soluble TNFα receptor fusion protein (etanercept) in corticosteroid refractory asthma: a double blind, randomised, placebo controlled trial (2008) (182)
IFN-γ–induced protein 10 is a novel biomarker of rhinovirus-induced asthma exacerbations (2007) (180)
Bronchial epithelium as a key regulator of airway allergen sensitization and remodeling in asthma. (2000) (163)
Asthmatic Bronchial Epithelium Is More Susceptible to Oxidant-Induced Apoptosis (2002) (158)
IL-4 Receptor α Is an Important Modulator of IL-4 and IL-13 Receptor Binding: Implications for the Development of Therapeutic Targets1 (2006) (157)
Autocrine ligands for the epidermal growth factor receptor mediate interleukin-8 release from bronchial epithelial cells in response to cigarette smoke. (2002) (153)
The role of the epidermal growth factor receptor in sustaining neutrophil inflammation in severe asthma (2003) (145)
Understanding the pathophysiology of severe asthma to generate new therapeutic opportunities. (2006) (144)
Signal transducer and activator of transcription 6 (STAT-6) expression and function in asthmatic bronchial epithelium. (2001) (142)
Expression of ErbB receptors and mucins in the airways of long term current smokers (2004) (139)
Double-stranded RNA induces disproportionate expression of thymic stromal lymphopoietin versus interferon-β in bronchial epithelial cells from donors with asthma (2010) (136)
Expression of c-erbB receptors and ligands in human bronchial mucosa. (1999) (135)
Increased expression of p21(waf) cyclin-dependent kinase inhibitor in asthmatic bronchial epithelium. (2003) (133)
Eosinophil recruitment following allergen challenge is associated with the release of the chemokine RANTES into asthmatic airways. (1996) (130)
Local genetic and environmental factors in asthma disease pathogenesis: chronicity and persistence mechanisms (2007) (129)
Asthmatic bronchial epithelium is more susceptible to oxidant-induced apoptosis. (2001) (124)
Expression of c-erbB receptors and ligands in the bronchial epithelium of asthmatic subjects. (2002) (123)
Shotgun proteomic analysis of human‐induced sputum (2006) (122)
Exogenous IFN-β has antiviral and anti-inflammatory properties in primary bronchial epithelial cells from asthmatic subjects exposed to rhinovirus. (2011) (117)
Mechanisms of airway epithelial damage: epithelial-mesenchymal interactions in the pathogenesis of asthma (2003) (115)
The epidermal growth factor receptor and its ligand family: their potential role in repair and remodelling in asthma. (1999) (112)
Breakdown in epithelial barrier function in patients with asthma: identification of novel therapeutic approaches. (2009) (111)
Thin film polycrystalline silicon nanowire biosensors. (2012) (109)
The Interaction of an Epidermal Growth Factor/Transforming Growth Factor α Tail Chimera with the Human Epidermal Growth Factor Receptor Reveals Unexpected Complexities* (1996) (105)
A novel ACE2 isoform is expressed in human respiratory epithelia and is upregulated in response to interferons and RNA respiratory virus infection (2021) (104)
ADAM33 expression in asthmatic airways and human embryonic lungs. (2005) (102)
Non-animal models of epithelial barriers (skin, intestine and lung) in research, industrial applications and regulatory toxicology. (2015) (100)
The soluble form of a disintegrin and metalloprotease 33 promotes angiogenesis: implications for airway remodeling in asthma. (2008) (100)
Physicochemical Characterization of Airborne Particulate Matter at a Mainline Underground Railway Station (2013) (98)
Structural studies on bioactive compounds. 23. Synthesis of polyhydroxylated 2-phenylbenzothiazoles and a comparison of their cytotoxicities and pharmacological properties with genistein and quercetin. (1994) (94)
The splicing and fate of ADAM33 transcripts in primary human airways fibroblasts. (2004) (93)
TNF-α-mediated bronchial barrier disruption and regulation by src-family kinase activation. (2013) (91)
Kinetic Analysis of the Interleukin-13 Receptor Complex* (2002) (90)
The genetics of asthma: ADAM33 as an example of a susceptibility gene. (2006) (89)
IL-13 receptor alpha 2: a regulator of IL-13 and IL-4 signal transduction in primary human fibroblasts. (2006) (88)
Epithelial injury and repair in airways diseases. (2013) (86)
Epithelial function and dysfunction in asthma (2014) (86)
Autophagy inhibition-mediated epithelial–mesenchymal transition augments local myofibroblast differentiation in pulmonary fibrosis (2019) (84)
Paracrine signalling during ZEB1-mediated epithelial–mesenchymal transition augments local myofibroblast differentiation in lung fibrosis (2018) (82)
Diesel exhaust increases EGFR and phosphorylated C-terminal Tyr 1173 in the bronchial epithelium (2008) (82)
Rethinking the pathogenesis of asthma. (2009) (78)
The chemokines: their potential role in allergic inflammation (1996) (78)
Long Term Culture of the A549 Cancer Cell Line Promotes Multilamellar Body Formation and Differentiation towards an Alveolar Type II Pneumocyte Phenotype (2016) (74)
Role of tumor necrosis factor alpha in asthma. (2004) (74)
Phenotypic and genetic aspects of epithelial barrier function in asthmatic patients (2017) (72)
Asthma: the importance of epithelial mesenchymal communication in pathogenesis. Inflammation and the airway epithelium in asthma. (2002) (72)
Leukocyte recruitment after local endobronchial allergen challenge in asthma. Relationship to procedure and to airway interleukin-8 release. (1996) (72)
Epithelial-mesenchymal transition contributes to pulmonary fibrosis via aberrant epithelial/fibroblastic cross-talk. (2019) (71)
Three-dimensional characterization of fibroblast foci in idiopathic pulmonary fibrosis (2016) (71)
Nanoscale dysregulation of collagen structure-function disrupts mechano-homeostasis and mediates pulmonary fibrosis (2018) (71)
Viral Stimuli Trigger Exaggerated Thymic Stromal Lymphopoietin Expression by Chronic Obstructive Pulmonary Disease Epithelium: Role of Endosomal TLR3 and Cytosolic RIG-I-Like Helicases (2011) (70)
Identification of lipocalin and apolipoprotein A1 as biomarkers of chronic obstructive pulmonary disease. (2010) (69)
Sputum IL-6 concentrations in severe asthma and its relationship with FEV1 (2010) (69)
Invited Lecture: Activation of the Epithelial Mesenchymal Trophic Unit in the Pathogenesis of Asthma (2001) (69)
Transforming Growth Factor-Beta Promotes Rhinovirus Replication in Bronchial Epithelial Cells by Suppressing the Innate Immune Response (2012) (68)
Epigenetic mechanisms silence a disintegrin and metalloprotease 33 expression in bronchial epithelial cells. (2008) (68)
Pollen exposure weakens innate defense against respiratory viruses (2019) (68)
Airway epithelial transcription factor NK2 homeobox 1 inhibits mucous cell metaplasia and Th2 inflammation. (2011) (66)
Contribution of eotaxin-1 to eosinophil chemotactic activity of moderate and severe asthmatic sputum. (2004) (66)
Barrier Disrupting Effects of Alternaria Alternata Extract on Bronchial Epithelium from Asthmatic Donors (2013) (65)
Altered protein tyrosine phosphorylation in asthmatic bronchial epithelium (2005) (65)
Identification of neutrophil chemotactie factors in bronchoalveolar lavage fluid of asthmatic patients (1997) (65)
Epithelial barrier function and immunity in asthma. (2014) (65)
A MicroRNA Network Dysregulated in Asthma Controls IL-6 Production in Bronchial Epithelial Cells (2014) (62)
Barrier responses of human bronchial epithelial cells to grass pollen exposure (2012) (62)
In vitro and ex vivo models of human asthma. (2013) (62)
The Effects on Bronchial Epithelial Mucociliary Cultures of Coarse, Fine, and Ultrafine Particulate Matter From an Underground Railway Station (2015) (62)
Osteopontin is expressed and functional in human eosinophils (2010) (61)
On the generation of allergic airway diseases: from GM-CSF to Kyoto. (2002) (61)
Nanomechanical assessment of human and murine collagen fibrils via atomic force microscopy cantilever-based nanoindentation. (2014) (60)
Targeting the epidermal growth factor receptor for therapy of carcinomas. (1996) (58)
On-chip epithelial barrier function assays using electrical impedance spectroscopy. (2010) (58)
Enhanced upregulation of smooth muscle related transcripts by TGFβ2 in asthmatic (myo) fibroblasts (2006) (57)
Squamous Metaplasia Is Increased in the Bronchial Epithelium of Smokers with Chronic Obstructive Pulmonary Disease (2016) (56)
The bronchial epithelium in asthma--much more than a passive barrier. (2001) (55)
Targeting the networks that underpin contiguous immunity in asthma and chronic obstructive pulmonary disease. (2007) (55)
Differential effects of EGF and amphiregulin on adhesion molecule expression and migration of colon carcinoma cells. (1997) (55)
Spiruchostatin A inhibits proliferation and differentiation of fibroblasts from patients with pulmonary fibrosis. (2012) (51)
Cysteinyl leukotrienes synergize with growth factors to induce proliferation of human bronchial fibroblasts. (2007) (49)
Altered Epithelial Gene Expression in Peripheral Airways of Severe Asthma (2017) (47)
ADAM33: a newly identified protease involved in airway remodelling. (2006) (45)
Epidermal growth factor induced tyrosine phosphorylation of nuclear proteins associated with translocation of epidermal growth factor receptor into the nucleus. (1994) (45)
The role of eosinophil major basic protein in angiogenesis (2009) (44)
The histone deacetylase inhibitor, romidepsin, as a potential treatment for pulmonary fibrosis (2017) (44)
Contribution of Bronchial Fibroblasts to the Antiviral Response in Asthma1 (2009) (41)
The role of ADAM33 in the pathogenesis of asthma (2004) (39)
Structure–mechanics relationships of collagen fibrils in the osteogenesis imperfecta mouse model (2015) (38)
Temporal Monitoring of Differentiated Human Airway Epithelial Cells Using Microfluidics (2015) (38)
Measurement of eotaxin (CCL11) in induced sputum supernatants: validation and detection in asthma. (2004) (37)
EGF-Induced Bronchial Epithelial Cells Drive Neutrophil Chemotactic and Anti-Apoptotic Activity in Asthma (2013) (37)
Modulation of the receptor binding affinity of amphiregulin by modification of its carboxyl terminal tail. (1995) (37)
Rhinovirus-16 Induced Release of IP-10 and IL-8 Is Augmented by Th2 Cytokines in a Pediatric Bronchial Epithelial Cell Model (2014) (36)
The in vitro biological activities of synthetic 18-O-methyl mycalamide B, 10-epi-18-O-methyl mycalamide B and pederin. (1997) (35)
The bronchial epithelium: translating gene and environment interactions in asthma (2001) (34)
Cigarette Smoke Causes Caspase-Independent Apoptosis of Bronchial Epithelial Cells from Asthmatic Donors (2015) (32)
Structure-function studies of ligand-induced epidermal growth factor receptor dimerization. (1998) (32)
The role of CD28-B7 costimulation in allergen-induced cytokine release by bronchial mucosa from patients with moderately severe asthma. (2001) (32)
Cellular crosstalk between airway epithelial and endothelial cells regulates barrier functions during exposure to double‐stranded RNA (2017) (32)
Identification of host miRNAs that may limit human rhinovirus replication. (2014) (31)
Effect of IL-13 receptor alpha2 levels on the biological activity of IL-13 variant R110Q. (2007) (31)
Contribution of the Transforming Growth Factor B-loop -Sheet to Binding and Activation of the Epidermal Growth Factor Receptor (*) (1995) (31)
Soluble ADAM33 initiates airway remodeling to promote susceptibility for allergic asthma in early life (2016) (31)
The bronchial epithelium in chronic and severe asthma (2001) (30)
Neutrophil influx and interleukin-8 release after segmental allergen or saline challenge in asthmatics. (1995) (29)
Expression of c-erbB receptors and ligands in human nasal epithelium. (2000) (29)
Growth inhibitory effects of FK506 and cyclosporin A independent of inhibition of calcineurin. (1995) (28)
Characterization of ciliated bronchial epithelium 1, a ciliated cell-associated gene induced during mucociliary differentiation. (2004) (26)
Adam 33 and its association with airway remodeling and hyperresponsiveness in asthma (2004) (26)
Enhancement of neutrophil function by the bronchial epithelium stimulated by epidermal growth factor (2008) (26)
The Severe Heterogeneous Asthma Research collaboration, Patient-centred (SHARP) ERS Clinical Research Collaboration: a new dawn in asthma research (2018) (24)
Cytoplasmic tail of IL-13Ralpha2 regulates IL-4 signal transduction. (2009) (23)
Cellular localization of interleukin 13 receptor alpha2 in human primary bronchial epithelial cells and fibroblasts. (2008) (22)
Tumor necrosis factor alpha (TNF-α) autoregulates its expression and induces adhesion molecule expression in asthma. (2011) (22)
ADAM 33: just another asthma gene or a breakthrough in understanding the origins of bronchial hyperresponsiveness? (2003) (22)
Contribution of host-derived growth factors to in vivo growth of a transplantable murine mammary carcinoma. (1994) (21)
Differential roles of IL-16 and CD28/B7 costimulation in the generation of T-lymphocyte chemotactic activity in the bronchial mucosa of mild and moderate asthmatic individuals. (2002) (21)
Low molecular weight components of pollen alter bronchial epithelial barrier functions (2015) (21)
Hydration and nanomechanical changes in collagen fibrils bearing advanced glycation end-products. (2019) (21)
The innate antiviral response upregulates IL-13 receptor α2 in bronchial fibroblasts. (2013) (21)
Engineering multi-layered tissue constructs using acoustic levitation (2019) (21)
Regulation of a disintegrin and metalloprotease-33 expression by transforming growth factor-β. (2012) (21)
Induction of a disintegrin and metalloprotease 33 during embryonic lung development and the influence of IL-13 or maternal allergy. (2009) (20)
A synthesis of 18-O-methyl mycalamide B (1996) (19)
Asthmatic and normal respiratory epithelial cells respond differently to mechanical apical stress. (2014) (19)
The association of the cytoplasmic domains of interleukin 4 receptor alpha and interleukin 13 receptor alpha 2 regulates interleukin 4 signaling. (2013) (19)
Autocrine ligands of the epithelial growth factor receptor mediate inflammatory responses to diesel exhaust particles (2014) (19)
Functional characterization of a novel 3D model of the epithelial-mesenchymal trophic unit (2017) (19)
A novel isoform of ACE2 is expressed in human nasal and bronchial respiratory epithelia and is upregulated in response to RNA respiratory virus infection (2020) (19)
Resistin‐like molecule‐β is induced following bronchoconstriction of asthmatic airways (2012) (19)
Induction of the epidermal growth factor receptor and its ligands in nasal epithelium by ozone. (2004) (19)
Mechanical Strain Causes Adaptive Change in Bronchial Fibroblasts Enhancing Profibrotic and Inflammatory Responses (2016) (18)
Multidomain binding of transforming growth factor alpha to the epidermal growth factor receptor. (1992) (18)
A unified model of c-erbB receptor homo- and heterodimerisation. (1998) (18)
The discovery and role of ADAM33, a new candidate gene for asthma (2004) (18)
Ligand-induced translocation of epidermal growth factor receptor to the nucleus of NR6/HER fibroblasts is serum dependent. (1995) (18)
Preliminary study of the cellular characteristics of primary bronchial fibroblasts in patients with asthma: expression of alpha-smooth muscle actin, fibronectin containing extra type III domain A, and smoothelin. (2012) (18)
Mast cells are permissive for rhinovirus replication: potential implications for asthma exacerbations (2017) (18)
Label-Free Differential Leukocyte Counts Using a Microfabricated, Single-Cell Impedance Spectrometer (2007) (17)
IL-1α mediates cellular cross-talk in the airway epithelial mesenchymal trophic unit (2016) (16)
Effects of anthralin and hypericin on growth factor signalling and cell proliferation in vitro. (1995) (15)
A Disintegrin and Metalloproteinase Domain‐9: A Novel Proteinase Culprit with Multifarious Contributions to Chronic Obstructive Pulmonary Disease (2018) (15)
Soluble tumor necrosis factor alpha (TNF-alpha) receptor (Enbrel) as an effective therapeutic strategy in chronic severe asthma* (2003) (15)
The Significance of Valine 33 as a Ligand-specific Epitope of Transforming Growth Factor α* (1996) (15)
Two newly established cell lines derived from the same colonic adenocarcinoma exhibit differences in EGF‐receptor ligand and adhesion molecule expression (1995) (14)
Bidirectional epithelial–mesenchymal crosstalk provides self-sustaining profibrotic signals in pulmonary fibrosis (2021) (14)
CD40 ligation protects bronchial epithelium against oxidant-induced caspase-independent cell death. (2006) (14)
Paracrine SPARC signaling dysregulates alveolar epithelial barrier integrity and function in lung fibrosis (2020) (14)
ADAM33: a newly identified gene in the pathogenesis of asthma. (2005) (14)
Frmd7 expression in developing mouse brain (2010) (13)
ADAM33: a novel therapeutic target for asthma (2003) (13)
Pseudohypoxic HIF pathway activation dysregulates collagen structure-function in human lung fibrosis (2021) (13)
Allergenic proteases cleave the chemokine CX3CL1 directly from the surface of airway epithelium and augment the effect of rhinovirus (2017) (12)
Synthesis of fragments of transforming growth factor alpha incorporating exo-2-Azabicyclo[2,2,1]heptane-3-carboxylic acids as proline substitutes (1995) (12)
Medium-term culture of normal human oral mucosa: a novel three-dimensional model to study the effectiveness of drugs administration. (2012) (12)
Beta-catenin/T-cell factor-mediated transcription is modulated by cell density in human bronchial epithelial cells. (2005) (12)
β-Catenin/T-cell factor-mediated transcription is modulated by cell density in human bronchial epithelial cells (2005) (12)
Inhibition of Pim1 kinase reduces viral replication in primary bronchial epithelial cells (2015) (12)
Genetics of Asthma (1993) (11)
Artificial airways for the study of respiratory disease (2011) (11)
Inhibition of Pim1 kinase, new therapeutic approach in virus-induced asthma exacerbations (2016) (11)
Deconvolution of RNA-Seq Analysis of Hyperbaric Oxygen-Treated Mice Lungs Reveals Mesenchymal Cell Subtype Changes (2020) (9)
A disintegrin and metalloprotease (ADAM) 33 protein in patients with pulmonary sarcoidosis (2012) (9)
Medium-term culture of primary oral squamous cell carcinoma in a three- dimensional model: effects on cell survival following topical 5-fluororacile delivery by drug-loaded matrix tablets. (2012) (9)
Involvement of the epidermal growth factor receptor in IL‐13–mediated corticosteroid‐resistant airway inflammation (2020) (9)
Epithelial dysregulation in obese severe asthmatics with gastro-oesophageal reflux (2019) (9)
The Epithelial-Mesenchymal Trophic Unit in Asthma (2000) (8)
Induction of anchorage-independent growth by amphiregulin. (1996) (8)
Biocompatibility of poly(2-alkyl-2-oxazoline) brush surfaces for adherent lung cell lines. (2015) (7)
Constrained peptide analogues of transforming growth factor-alpha residues cysteine 21-32 are mitogenically active. Use of proline mimetics to enhance biological potency. (1995) (7)
Chronological expression of Ciliated Bronchial Epithelium 1 during pulmonary development (2009) (7)
Urinary epidermal growth factor (hEGF) levels in patients with carcinomas of the breast, colon and rectum. (1990) (7)
Application of functional genomics to study of inflammatory airways disease (1999) (7)
A disintegrin and metalloprotease 33 expression in asthmatic airways and human embryonic lungs (2005) (7)
Solution structure of the mEGF/TGFα44−50 chimeric growth factor (2001) (6)
Superresolved polarization-enhanced second-harmonic generation for direct imaging of nanoscale changes in collagen architecture (2021) (6)
New insights into asthma pathogenesis (2002) (6)
Modulation of Human Airway Barrier Functions during Burkholderia thailandensis and Francisella tularensis Infection Running Title: Airway Barrier Functions during Bacterial Infections (2016) (6)
Identification and possible functions of ADAM33 as an asthma susceptibility gene (2004) (6)
Vulnerability to acid reflux of the airway epithelium in severe asthma (2022) (5)
A method for the generation of large numbers of dendritic cells from CD34+ hematopoietic stem cells from cord blood (2019) (5)
Solution structure of the mEGF/TGFalpha44-50 chimeric growth factor. (2002) (5)
AIRWAY INFLAMMATION AND REMODELLING IN ASTHMA – CAUSE AND EFFECT ? (5)
Establishment of a pulmonary epithelial barrier on biodegradable poly-L-lactic-acid membranes (2019) (4)
Evaluation of novel LOXL2-selective inhibitors in models of pulmonary fibrosis (2017) (3)
Real-time monitoring of epithelial barrier function by impedance spectroscopy in a microfluidic platform. (2022) (3)
Quantitative Proteomic Analysis in Alveolar Type II Cells Reveals the Different Capacities of RAS and TGF-β to Induce Epithelial–Mesenchymal Transition (2021) (3)
Chapter 7 – Airway Remodeling (2002) (3)
Paracrine SPARC signaling dysregulates alveolar epithelial barrier integrity and function in lung fibrosis (2020) (3)
The SPDEF Network Regulates Mucus Cell Differentiation In Asthma (2011) (3)
Super-resolved polarisation-enhanced second harmonic generation for direct imaging of nanoscale changes in collagen architecture (2020) (3)
Upregulation of epithelial metallothioneins by metal-rich ultrafine particulate matter from an underground railway. (2020) (2)
Up-regulation of epithelial and fibroblast prostaglandin D2 CRTH2-receptors in asthma (2007) (2)
Evaluation of romidepsin (FK228) as a potential therapy for idiopathic pulmonary fibrosis (IPF) (2016) (2)
The effects of interferon beta on cold-induced asthma exacerbations (2012) (2)
HIF pathway activation is a core regulator of collagen structure-function in lung fibrosis (2020) (2)
Spiruchostatin A Inhibits Proliferation And Differentiation Of Primary Fibroblasts From Patients With Interstitial Lung Disease (2010) (2)
Polycrystalline silicon nanowires patterned by top-down lithography for biosensor applications (2010) (1)
The Epithelial Expression of TNF-alpha Is Enhanced in Severe Asthma: Relevance of NFκB and Response to Viral and Bacterial Stimuli. (2009) (1)
Regarding epithelial dysregulation in obese severe asthmatics with gastro-oesophageal reflux (2019) (1)
Inhibition of collagen cross-links by novel LOXL2 selective inhibitors in an in-vitro model of fibroblastic foci of IPF (2016) (1)
Differential toxicity in an alveolar epithelial cell line of fine particulate matter from brakewear, roadwear, and diesel exhaust (2022) (1)
Erratum: Blume, C., et al. Modulation of Human Airway Barrier Functions during Burkholderia thailandensis and Francisella tularensis Infection Running Title: Airway Barrier Functions during Bacterial Infections. Pathogens 2016, 5, 53 (2020) (1)
Examining lysyl oxidase-like modulation of collagen architecture in 3D spheroid models of idiopathic pulmonary fibrosis via second-harmonic generation microscopy (2021) (1)
A novel ACE2 isoform is expressed in human respiratory epithelia and is upregulated in response to interferons and RNA respiratory virus infection (2021) (1)
Sensors for chemical detection based on top-down fabricated polycrystalline silicon nanowires (2010) (1)
Enhancement of neutrophil function by the bronchial epithelium stimulated by EGF (2007) (1)
A Synthesis of 18‐O‐Methyl Mycalamide B. (1997) (1)
Three-Dimensional Characterisation of Fibroblast Foci in Idiopathic Pulmonary Fibrosis (2016) (1)
Rhinovirus 2A is the key protease responsible for instigating the early block to gene expression in infected cells (2019) (1)
The Depsipeptide HDAC Inhibitor FK228 (Romidepsin) Has Anti-Fibrotic Properties In Fibrotic Primary Pulmonary Fibroblasts (2011) (1)
Effects Of IL-13 And IL-17 On Fibroblasts Derived From The Proximal And Distal Airways (2011) (1)
The Impact Of TNFA On The Function Of The Airway Epithelial Barrier (2011) (1)
Defective Epithelial Barrier Function In Asthma (2011) (1)
Airway hyperresponsiveness in offspring from mothers with allergic airway inflammation during pregnancy is muscarinic receptor and ADAM33 dependent (2020) (1)
Validation of a Method for Automatic Detection of Lung Sounds in Fibrotic Interstitial Lung Disease (2016) (1)
The Scavenger Receptor SCARA5 Is Expressed In Human Alveolar Epithelial Cells (2010) (1)
Neutrophil Chemotactic Activity In The Bronchoalveolar Lavage Fluid Of Asthmatics (1993) (0)
On chip label-free epithelial barrier function assay in artificial human asthmatic airway (2009) (0)
Immunity Essay Does Asthma Originate in the Airway Structural Cells ? (2009) (0)
ADAM33 protein found in bronchial brushings and biopsies is increased in bronchial carcinomas (2012) (0)
Interferon-beta for anti-virus treatment of respiratory diseases (2005) (0)
Engineering multi-layered tissue constructs using acoustic levitation (2019) (0)
Shipping-related particulate matter air pollution – source-specific effects on bronchial epithelial cells (2019) (0)
Differentiated Bronchial Epithelial Cells Suppress Antigen-Mediated Mast Cell Activation Following Co-Culture (2012) (0)
ADAM33 is involved in post-natal airway hyperresponsiveness caused by maternal allergic airway inflammation (2018) (0)
Late-breaking abstract: Inhibition of Pim1 kinase augments the anti-viral response to rhinovirus infection (2014) (0)
Late Breaking Abstract - Investigation of the epithelial-mesenchymal paracrine interactions in lung tissue repair and fibrosis (2019) (0)
Late-breaking abstract: Airway remodelling induced by ADAM33 is reversible (2014) (0)
Late-breaking abstract: Inhibition of Pim1 kinase augments the anti-viral response to rhinovirus infection (2014) (0)
Romidepsin (FK228) target focal adhesion kinase (FAK) expression in lung fibrosis (2015) (0)
A novel short isoform of ACE2 is expressed in ciliated airway epithelium and is induced by interferon and rhinovirus infection but not SARS-COV-2; implications for COVID-19 interferon treatment (2021) (0)
Molecular mechanisms in allergy and clinical immunology Molecular pathology of allergic airway disease. II: Upper airway disease (2000) (0)
Structural Studies on Bioactive Compounds. Part 23. Synthesis of Polyhydroxylated 2-Phenylbenzothiazoles and a Comparison of Their Cytotoxicities and Pharmacological Properties with Genistein and Quercetin. (2010) (0)
Abstracts of the XXX Congress of the European Academy of Allergy and Clinical Immunology. Istanbul, Turkey. June 11-15, 2011. (2011) (0)
Late-breaking abstract: Repeated bronchoconstriction without additional inflammation is sufficient to induce airway remodelling in asthma (2011) (0)
Expression And Function Of A Novel Membrane-Spanning Protein, Ms4a8b, In The Airway Epithelium (2014) (0)
S32 Cyclical mechanical stretch enhances the pro-fibrotic responses of primary embryonic foetal fibroblasts, but not ADAM33 expression (2010) (0)
Expression Of Interleukin 13 Receptor ± 2 In Human Bronchial Fibroblasts Requires De Novo Protein Synthesis (2012) (0)
Clinical Development of Inhaled Interferon Beta-1a (SNG001) for the Treatment of Patients With COVID-19 in the Home and Hospital Settings (2023) (0)
The Innate Anti-Viral Response Upregulates IL-13R±2 In Bronchial Fibroblasts (2012) (0)
Endogenous IL-6 Phosphorylates STAT3 in Primary Bronchial Fibroblasts. (2009) (0)
The Role Of Signal Transducer And Activator Of Transcription (STAT) 3 In Interleukin-4 Signalling In Primary Fibroblasts (2011) (0)
The Airway Mucus Regulating Transcription Factor SPDEF Is Increased In BALF In Asthma (2012) (0)
Epithelial cell monolayer barrier functioning assay using electrical impedance technologies (2009) (0)
EGF-Receptor Binding Peptides from Transforming Growth Factor Alpha (TGF Alpha): Evidence for a Multi-Domain Interaction, (1992) (0)
Inflammatory biomarker sensing using rectangular polycrystalline silicon nanowires made by dry etching (2011) (0)
Cyclical Mechanical Stretch Enhances the Proinflammatory but not Profibrotic Responses of Asthmatic Fibroblasts (2010) (0)
Monitoring kinetics in the artificial human asthmatic airway using electrical impedance spectroscopy (2008) (0)
A validated hypoxia-inducible factor (HIF) signature across tissue compartments predicts clinical outcome in human lung fibrosis (2022) (0)
Wnt Signal Transduction in Adult Human Bronchial Epithelial Cells (2003) (0)
Infection Of Primary Bronchial Epithelial Cells With Rhinovirus Causes Disruption Of The Epithelial Barrier And DC Activation (2011) (0)
Molecular mechanisms of the synergy between cysteinyl-leukotrienes and receptor tyrosine kinase growth factors on human bronchial fibroblast proliferation (2006) (0)
MicroRNA-155 Counteracts The Increase Of Rhinovirus Replication Induced By TGF-Beta In Human Broncho-Epithelial Cells (BECs) (2012) (0)
Low cost nanowire biosensor fabrication using thin film amorphous silicon crystallisation technologies (2010) (0)
Corrigendum to Nanomechanical assessment of human and murine collagen fibrils via atomic force microscopy cantilever-based nanoindentation [J. Mech. Behav. Biomed. Mater. 39 (2014) 9–26] (2015) (0)
Hypoxia-inducible factor pathway activation promotes bone-type collagen cross-linking in Idiopathic Pulmonary Fibrosis (2019) (0)
The respiratory epithelium expresses ACE2 isoforms differentially in response to interferons: Implications for IFN-ß as COVID-19 therapy (2022) (0)
Investigating the effects of metals within particulate matter in human alveolar epithelial cells (2022) (0)
Polmunary epithelial barrier formation on biodegradable poly-L-lactic-acid (PLLA) membrane (2016) (0)
Epithelial Barrier Leakiness in Asthma (2017) (0)
Source-related composition and toxicological effects of shipping-associated particulate matter (2022) (0)
Pro-fibrotic Effect Of Dexamethasone In Human Airway Fibroblasts (2012) (0)
Interleukin -13 (IL-13) Decreases Barrier Function in Primary Bronchial Epithelial Cells. (2009) (0)
Alveolar and Fibroblast Foci Specific Genome-Wide Gene Expression Profiling Identifies Common Dysregulated Expression of CREB1, a Regulator Across Cell Types, in IPF (2019) (0)
Paracrine signalling during ZEB1-mediated epithelial–mesenchymal transition augments local myofibroblast differentiation in lung fibrosis (2018) (0)
P079 Evaluation of romidepsin (FK228) as a potential therapy for idiopathic pulmonary fibrosis (IPF) (2016) (0)
IL-33 Induces an Antiviral Signature in Mast Cells but Enhances Their Permissiveness for Human Rhinovirus Infection (2022) (0)
The Effect of Respirable Particles on IL-8 Release from Airway Epithelial Cells (2002) (0)
The Physicochemical And Inflammogenic Properties Of Metal-Rich Airborne Particulates Collected At An Underground Railway Station (2012) (0)
Characterisation Of Grass Pollen Derived Substances Modulating The Barrier Functions Of Bronchial Epithelial Cells (2011) (0)
The Co-Operative Effects of der P Allergen and IL-4 OR IL-13 in Cytokine Release by Bronchial Epithelial Cell Cultures of Allergic Asthmatics (2001) (0)
Epithelial Cells Allergen on Normal and Asthmatic Bronchial Cooperative Effects of Th2 Cytokines and (2002) (0)
Effect of hydrophobic substituents on the rate of formation of cyclic peptides using TGFα residues 21–32 peptides (1993) (0)
LSC 2013 abstract - Mast cells support rhinovirus but not respiratory syncytial virus replication and contribute to the pro-inflammatory response to rhinovirus (2013) (0)
Characterization of CBE1, a ciliated cell-associated gene induced during mucociliary differentiation (2004) (0)
Novel cellular effects of ultrafine particulate matter from an underground railway station uncovered through RNAseq (2019) (0)
CROSS-LINK DENSITY AND TYPE ARE STRONG DETERMINANTS OF COLLAGEN FIBRIL NANOELASTICITY (2010) (0)
The Asthmatic Bronchial Epithelium Regulates Neutrophil Migration. (2009) (0)
human embryonic lungs. (2005) (0)
Correlation between lung sounds and HRCT signs of pulmonary fibrosis: a blinded prospective study (2017) (0)
Characterization of a novel three‐dimensional outgrowth model of human bronchial mucosa (2011) (0)
Expression and function of a novel membrane-spanning protein, MS4A8B, in the human airways (2015) (0)
Differential effects of the histone deacetylase (HDAC) inhibitor, Romidepsin (FK228), on IPF fibroblasts and alveolar epithelial cells. (2014) (0)
Constrained Peptide Analogues of Transforming Growth Factor-α Residues Cysteine 21-32 Are Mitogenically Active (1995) (0)
Interleukin-33: a double-edged sword in mast cell responses to rhinovirus infection (2019) (0)
The Induction Of The SPDEF Network By Rhinovirus Infection Of Primary Bronchial Epithelial Cells From Cystic Fibrosis Patients And Healthy Control Subjects (2012) (0)
Soluble ADAM33 augments the pulmonary innate immune response promoting susceptibility to allergic airway inflammation (2018) (0)
Studying Innate Interferon Responses to Human Rhinovirus Infection in Cultured Bronchial Epithelial Cells from Asthmatic Children. (2009) (0)
Interferon-beta antiviral therapy for airway diseases (2005) (0)
TGFß1 induces collagen deposition and increased tissue stiffness in sarcoidosis fibroblasts grown in a novel, long term, 3D culture system (2019) (0)
Th-2 Cytokines Regulate Transforming Growth Factor Alpha (TGFα) and Endothelin (ET-1) Production by Asthmatic Bronchial Epithelial Cells (2002) (0)
LSC Abstract – Role For IL-1alpha in viral-induced inflammatory responses in an epithelial-fibroblast co-culture model of the airway mucosa (2015) (0)
In vitro models of bronchialepithelial cell infection (2007) (0)
Quantitative proteomic analysis in ATII cells reveals the different capacities of 1 RAS and TGF-β to induce EMT 2 (2021) (0)
Chronological expression of ciliated bronchial epithelim 1 in mouse and human pulmonary differentiation (2006) (0)
Soluble Adam33 Is Increased And Enzymatically Active In BALF And Is Associated With Bronchial Hyperresponsiveness In Il-13 Overexpressing Mice (2012) (0)
LSC Abstract – Cellular crosstalk between airway epithelial and endothelial cells during viral infections (2015) (0)
Corticosteroid-resistant neutrophilic airway inflammation and hyperresponsiveness caused by IL-13 (2018) (0)
Characterisation of a novel in vitro model of fibroblastic foci (2014) (0)
Interferon Beta (IFN²) Is Equally Effective At Inhibiting Rhinovirus Infection In Primary Bronchial Epithelial Cells Of Long Term Smokers (with And Without COPD) And Younger Non-smoking Subjects (2010) (0)
ADAM33 in embryonic lungs (2005) (0)
Poster Presentation (2022) (0)
P108 Novel LOXL2 selective small molecule inhibitors reduce cross-link formation and alter matrix properties in an in vitro fibroblastic foci model of IPF (2016) (0)
Impedance spectroscopy for label-free differential leukocyte counts (2007) (0)
Analysing disease-specific variants of thymic stromal lymphopoietin (TSLP) in asthma (2015) (0)
Polarised Release Of Mediators By Differentiated Primary Bronchial Epithelial Cells From Normal And Asthmatic Donors In Response To Grass Pollen (2012) (0)
The epigenetic modulator 5-aza-2’-deoxycytidine reduces the fibrotic response of human lung fibroblasts to TGFß1 in a novel, long term, 3D cell culture system (2019) (0)
An ex vivo model of the human airways to study the effects of long-term exposure to Space conditions (2015) (0)
Rhinovirus 2A is the predominant protease responsible for instigating the early block to gene expression encountered in infected cells (2019) (0)
Poly I:C-Activated Epithelial Cells Promote The Maturation Of Dendritic Cells In A Co-Culture Model (2010) (0)
Antiviral Effects of Interferon beta (IFNβ) in Asthmatic Bronchial Epithelial Cell Cultures. (2009) (0)
Regulation of ectodomain shedding of ADAM33 in vitro and in vivo (2019) (0)
The effect of double-stranded RNA on extracellular matrix deposition in an in vitro model of the airway mucosa (2018) (0)

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