Donna M. Peehl
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Donna M. Peehl's Degrees
- PhD Biochemistry University of California, Berkeley
- Bachelors Biology University of California, Berkeley
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(Suggest an Edit or Addition)Donna M. Peehl's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Tumor microenvironment derived exosomes pleiotropically modulate cancer cell metabolism (2016) (599)
- Antiproliferative effects of 1,25-dihydroxyvitamin D3 on primary cultures of human prostatic cells. (1994) (531)
- Prostate-specific antigen (PSA) is an insulin-like growth factor binding protein-3 protease found in seminal plasma. (1992) (525)
- Glucocorticoids can promote androgen-independent growth of prostate cancer cells through a mutated androgen receptor (2000) (523)
- Vitamin D and prostate cancer: 1,25 dihydroxyvitamin D3 receptors and actions in human prostate cancer cell lines. (1993) (493)
- Role of glutathione depletion and reactive oxygen species generation in apoptotic signaling in a human B lymphoma cell line (2002) (429)
- Insulin-like growth factors (IGFs), IGF receptors, and IGF-binding proteins in primary cultures of prostate epithelial cells. (1991) (368)
- Human cell hybrids: analysis of transformation and tumorigenicity. (1982) (349)
- Activation of EphA receptor tyrosine kinase inhibits the Ras/MAPK pathway (2001) (342)
- Keratin immunoreactivity in the benign and neoplastic human prostate. (1985) (294)
- Biological effects of prostate specific antigen as an insulin-like growth factor binding protein-3 protease. (1994) (289)
- Elevated expression of inhibitor of apoptosis proteins in prostate cancer. (2003) (252)
- Expression of CCL5 (RANTES) and CCR5 in prostate cancer (2006) (245)
- Regulation of prostaglandin metabolism by calcitriol attenuates growth stimulation in prostate cancer cells. (2005) (231)
- Elevated levels of insulin-like growth factor-binding protein-2 in the serum of prostate cancer patients. (1993) (221)
- Reduced 1alpha-hydroxylase activity in human prostate cancer cells correlates with decreased susceptibility to 25-hydroxyvitamin D3-induced growth inhibition. (2001) (218)
- DNA methylation profiling reveals novel biomarkers and important roles for DNA methyltransferases in prostate cancer. (2011) (218)
- Actions of vitamin D3, analogs on human prostate cancer cell lines: comparison with 1,25-dihydroxyvitamin D3. (1995) (209)
- SMAD3 represses androgen receptor-mediated transcription. (2001) (201)
- Inhibition of p38 by vitamin D reduces interleukin-6 production in normal prostate cells via mitogen-activated protein kinase phosphatase 5: implications for prostate cancer prevention by vitamin D. (2006) (196)
- Prostate specific antigen cleaves parathyroid hormone-related protein in the PTH-like domain: inactivation of PTHrP-stimulated cAMP accumulation in mouse osteoblasts. (1996) (193)
- Primary cell cultures as models of prostate cancer development. (2005) (188)
- Expression and Characterization of Recombinant Type 2 3α-Hydroxysteroid Dehydrogenase (HSD) from Human Prostate: Demonstration of Bifunctional 3α/17β-HSD Activity and Cellular Distribution (1997) (184)
- Antiproliferative and proapoptotic activities of triptolide (PG490), a natural product entering clinical trials, on primary cultures of human prostatic epithelial cells. (2002) (180)
- Chemopreventive anti-inflammatory activities of curcumin and other phytochemicals mediated by MAP kinase phosphatase-5 in prostate cells. (2007) (179)
- Inhibition of prostate cancer growth by vitamin D: Regulation of target gene expression (2003) (178)
- Frequency and pattern of karyotypic abnormalities in human prostate cancer. (1990) (172)
- The IGF axis in the prostate. (1994) (170)
- Molecular and cellular pathogenesis of benign prostatic hyperplasia. (2004) (170)
- Expression of senescence-associated beta-galactosidase in enlarged prostates from men with benign prostatic hyperplasia. (2000) (165)
- Analysis of vitamin D‐regulated gene expression in LNCaP human prostate cancer cells using cDNA microarrays (2004) (144)
- Selection of human cervical epithelial cells that possess reduced apoptotic potential to low-oxygen conditions. (1997) (144)
- Altered SMRT levels disrupt vitamin D3 receptor signalling in prostate cancer cells (2004) (139)
- The current state of preclinical prostate cancer animal models (2008) (136)
- Induction of smooth muscle cell phenotype in cultured human prostatic stromal cells. (1997) (135)
- Human type 3 3alpha-hydroxysteroid dehydrogenase (aldo-keto reductase 1C2) and androgen metabolism in prostate cells. (2003) (125)
- Hepcidin regulation in prostate and its disruption in prostate cancer. (2015) (121)
- Aldo-keto reductase (AKR) 1C3: Role in prostate disease and the development of specific inhibitors (2006) (115)
- Molecular activity of 1,25-dihydroxyvitamin D3 in primary cultures of human prostatic epithelial cells revealed by cDNA microarray analysis (2004) (114)
- Two mutations identified in the androgen receptor of the new human prostate cancer cell line MDA PCa 2a. (1999) (114)
- Insulin-like growth factor axis abnormalities in prostatic stromal cells from patients with benign prostatic hyperplasia. (1994) (112)
- 1α,25-Dihydroxyvitamin D3 Inhibits Prostate Cancer Cell Growth by Androgen-Dependent and Androgen-Independent Mechanisms. (2000) (107)
- Erratum: Glucocorticoids can promote androgen-independent growth of prostate cancer cells through a mutated androgen receptor (Nature Medicine (2000) 6 (703-706)) (2000) (107)
- Identification of the Major Oxidative 3α-Hydroxysteroid Dehydrogenase in Human Prostate That Converts 5α-Androstane-3α,17β-diol to 5α-Dihydrotestosterone: A Potential Therapeutic Target for Androgen-Dependent Disease (2006) (106)
- Tumor‐selective killing by selenite in patient‐matched pairs of normal and malignant prostate cells (2006) (102)
- Transformation of human neonatal prostate epithelial cells by strontium phosphate transfection with a plasmid containing SV40 early region genes. (1989) (101)
- Clonal growth of human prostatic epithelial cells is stimulated by fibroblasts (1989) (100)
- 1α,25-Dihydroxyvitamin D3 Actions in LNCaP Human Prostate Cancer Cells Are Androgen-Dependent. (1997) (100)
- Lipofection-mediated immortalization of human prostatic epithelial cells of normal and malignant origin using human papillomavirus type 18 DNA. (1994) (98)
- Novel stimulatory role for insulin‐like growth factor binding protein‐2 in prostate cancer cells (2003) (97)
- Novel pathways that contribute to the anti-proliferative and chemopreventive activities of calcitriol in prostate cancer (2007) (93)
- Metabolic Reprogramming and Validation of Hyperpolarized 13C Lactate as a Prostate Cancer Biomarker Using a Human Prostate Tissue Slice Culture Bioreactor (2013) (92)
- Microfluidic integration for automated targeted proteomic assays (2012) (91)
- A strategy for tissue self-organization that is robust to cellular heterogeneity and plasticity (2015) (87)
- Preferential production of latent transforming growth factor β‐2 by primary prostatic epithelial cells and its activation by prostate‐specific antigen (2005) (87)
- Induction of Androgen Receptor by 1α,25-Dihydroxyvitamin D3 and 9-cis Retinoic Acid in LNCaP Human Prostate Cancer Cells. (1999) (86)
- Genistein potentiates the growth inhibitory effects of 1,25-dihydroxyvitamin D3 in DU145 human prostate cancer cells: Role of the direct inhibition of CYP24 enzyme activity (2005) (86)
- Pathways mediating the growth-inhibitory actions of vitamin D in prostate cancer. (2003) (85)
- NO to cancer: The complex and multifaceted role of nitric oxide and the epigenetic nitric oxide donor, RRx-001☆ (2015) (83)
- Preclinical activity of ketoconazole in combination with calcitriol or the vitamin D analogue EB 1089 in prostate cancer cells. (2002) (81)
- Activated ki‐ras oncogene in human prostatic adenocarcinoma (1987) (78)
- Tumor‐promoting phenotype of CD90hi prostate cancer‐associated fibroblasts (2009) (77)
- Vitamin A regulates proliferation and differentiation of human prostatic epithelial cells (1993) (77)
- Redox modulation of human prostate carcinoma cells by selenite increases radiation-induced cell killing. (2005) (77)
- Attenuated response of p53 and p21 in primary cultures of human prostatic epithelial cells exposed to DNA-damaging agents. (1995) (77)
- Retinol metabolism and lecithin:retinol acyltransferase levels are reduced in cultured human prostate cancer cells and tissue specimens. (2002) (76)
- Anchorage-independent growth of normal human fibroblasts. (1981) (74)
- Transcript profiling of the androgen signal in normal prostate, benign prostatic hyperplasia, and prostate cancer. (2006) (74)
- Calcitriol as a Chemopreventive and Therapeutic Agent in Prostate Cancer: Role of Anti‐Inflammatory Activity (2007) (73)
- Comprehensive Drug Testing of Patient-derived Conditionally Reprogrammed Cells from Castration-resistant Prostate Cancer. (2017) (73)
- Prostate specific antigen role and function (1995) (73)
- Coordinate loss of MAP3K7 and CHD1 promotes aggressive prostate cancer. (2015) (71)
- Safety and activity of RRx-001 in patients with advanced cancer: a first-in-human, open-label, dose-escalation phase 1 study. (2015) (70)
- Expression of transforming growth factor‐beta 1 and growth in soft agar differentiate prostate carcinoma‐associated fibroblasts from normal prostate fibroblasts (2004) (70)
- Human prostate epithelium lacks Wee1A-mediated DNA damage-induced checkpoint enforcement (2007) (70)
- A glucocorticoid-responsive mutant androgen receptor exhibits unique ligand specificity: therapeutic implications for androgen-independent prostate cancer. (2002) (70)
- Topology of NGEP, a prostate-specific cell:cell junction protein widely expressed in many cancers of different grade level. (2008) (69)
- Vitamin D receptor start codon polymorphism (FokI) and prostate cancer progression. (2003) (69)
- Inhibition of prostaglandin synthesis and actions by genistein in human prostate cancer cells and by soy isoflavones in prostate cancer patients (2009) (68)
- Imaging the glycosylation state of cell surface glycoproteins by two-photon fluorescence lifetime imaging microscopy. (2013) (67)
- Targeting monoamine oxidase A in advanced prostate cancer (2010) (67)
- Trop2 is a driver of metastatic prostate cancer with neuroendocrine phenotype via PARP1 (2020) (66)
- Phosphorylcholine‐Coated Semiconducting Polymer Nanoparticles as Rapid and Efficient Labeling Agents for In Vivo Cell Tracking (2014) (66)
- Elevated Serum MicroRNA Levels Associate with Absence of High-Grade Prostate Cancer in a Retrospective Cohort (2015) (64)
- Tissue slice grafts: an in vivo model of human prostate androgen signaling. (2010) (64)
- 1alpha,25-dihydroxyvitamin D3 actions in LNCaP human prostate cancer cells are androgen-dependent. (1997) (64)
- Expression of matrix metalloproteinase‐2 and ‐9 and their inhibitors, tissue inhibitor of metalloproteinase‐1 and ‐2, in primary cultures of human prostatic stromal and epithelial cells * † (2002) (64)
- The role of insulin-like growth factors in prostate biology. (1996) (64)
- 7S nerve growth factor is an insulin-like growth factor-binding protein protease. (1996) (64)
- Expression and characterization of recombinant type 2 3 alpha-hydroxysteroid dehydrogenase (HSD) from human prostate: demonstration of bifunctional 3 alpha/17 beta-HSD activity and cellular distribution. (1997) (62)
- p16INK4A mediates cyclin dependent kinase 4 and 6 inhibition in senescent prostatic epithelial cells. (2000) (62)
- Analysis of prostatic tumor cultures using fluorescence in-situ hybridization (FISH). (1992) (59)
- Polymorphisms in the androgen receptor and type II 5α‐reductase genes and prostate cancer prognosis (2002) (58)
- CXCR4 and CXCL12 (SDF-1) in Prostate Cancer (2004) (58)
- Calcitriol and genistein actions to inhibit the prostaglandin pathway: potential combination therapy to treat prostate cancer. (2007) (58)
- Identification of insulin-like growth factor-binding protein-3 (IGFBP-3) fragments and IGFBP-5 proteolytic activity in human seminal plasma: a comparison of normal and vasectomized patients. (1994) (57)
- Growth responses of normal, benign hyperplastic, and malignant human prostatic epithelial cells in vitro to cholera toxin, pituitary extract, and hydrocortisone (1986) (57)
- Mechanisms of vitamin D-mediated growth inhibition in prostate cancer cells: inhibition of the prostaglandin pathway. (2006) (57)
- In vitro studies of human prostatic epithelial cells: attempts to identify distinguishing features of malignant cells. (1989) (56)
- The role of differentiation in the suppression of tumorigenicity in human cell hybrids (1982) (56)
- Down-regulation of a calmodulin-related gene during transformation of human mammary epithelial cells. (1990) (56)
- Identification of the major oxidative 3alpha-hydroxysteroid dehydrogenase in human prostate that converts 5alpha-androstane-3alpha,17beta-diol to 5alpha-dihydrotestosterone: a potential therapeutic target for androgen-dependent disease. (2006) (56)
- Cadmium-induced neoplastic transformation of human prostate epithelial cells. (2002) (55)
- Cytogenetic evaluation of 20 cultured primary prostatic tumors. (1991) (55)
- Clonal growth of human keratinocytes with small amounts of dialyzed serum (1980) (55)
- Distinctive gene expression of prostatic stromal cells cultured from diseased versus normal tissues (2007) (54)
- 1alpha,25-dihydroxyvitamin D3 inhibits prostate cancer cell growth by androgen-dependent and androgen-independent mechanisms. (2000) (54)
- Decreased expression of Wilms' tumor gene WT-1 and elevated expression of insulin growth factor-II (IGF-II) and type 1 IGF receptor genes in prostatic stromal cells from patients with benign prostatic hyperplasia. (1997) (53)
- Suppression of Tak1 promotes prostate tumorigenesis. (2012) (52)
- Characterization of adult human prostatic epithelial-cells immortalized by polybrene-induced DNA transfection with a plasmid containing an origin-defective sv40-genome. (1994) (52)
- Parathyroid hormone‐related protein (PTHrP) is an epidermal growth factor‐regulated secretory product of human prostatic epithelial cells (1996) (52)
- Oncogenes in prostate cancer. An update (1993) (51)
- Bioorthogonal Labeling of Human Prostate Cancer Tissue Slice Cultures for Glycoproteomics. (2017) (50)
- The role of vitamin D and retinoids in controlling prostate cancer progression. (2003) (50)
- The significance of monoamine oxidase-A expression in high grade prostate cancer. (2008) (49)
- The insulin-like growth factor system in the prostate (2004) (49)
- Cytostatic effects of suramin on prostate cancer cells cultured from primary tumors. (1991) (48)
- Centrosomal PKCbetaII and pericentrin are critical for human prostate cancer growth and angiogenesis. (2008) (48)
- In Vitro proton spectroscopy of normal and abnormal prostate (1991) (48)
- Carbohydrate Sequence of the Prostate Cancer-associated Antigen F77 Assigned by a Mucin O-Glycome Designer Array* (2014) (48)
- Are primary cultures realistic models of prostate cancer? (2004) (47)
- Serum-free growth of adult human prostatic epithelial cells (1986) (47)
- Human papillomavirus detection by polymerase chain reaction in benign and malignant prostate tissue is dependent on the primer set utilized. (1997) (46)
- Oxidative 3α-hydroxysteroid dehydrogenase activity of human type 10 17β-hydroxysteroid dehydrogenase (2003) (46)
- Optimization and comprehensive characterization of a faithful tissue culture model of the benign and malignant human prostate (2013) (45)
- Induction of androgen receptor by 1alpha,25-dihydroxyvitamin D3 and 9-cis retinoic acid in LNCaP human prostate cancer cells. (1999) (45)
- Validation of Hyperpolarized 13 C Lactate as a Prostate Cancer Biomarker Using a Human Prostate Tissue Slice Culture Bioreactor (2012) (44)
- Keratin expression: a measure of phenotypic modulation of human prostatic epithelial cells by growth inhibitory factors (1994) (44)
- The m6A RNA demethylase FTO is a HIF-independent synthetic lethal partner with the VHL tumor suppressor (2020) (44)
- Primary culture model of peroxisome proliferator‐activated receptor γ activity in prostate cancer cells (2003) (44)
- Basic FGF, EGF, and PDGF modify TGFβ‐induction of smooth muscle cell phenotype in human prostatic stromal cells (1998) (43)
- Serial culture of adult human prostatic epithelial cells (1985) (43)
- Interaction of nuclear receptor ligands with the Vitamin D signaling pathway in prostate cancer (2004) (43)
- Preclinical trial of a new dual mTOR inhibitor, MLN0128, using renal cell carcinoma tumorgrafts (2014) (43)
- Mechanisms of decreased Vitamin D 1α-hydroxylase activity in prostate cancer cells (2004) (43)
- Epigenetic effects of RRx-001: a possible unifying mechanism of anticancer activity (2015) (42)
- Metalloporphyrin synergizes with ascorbic acid to inhibit cancer cell growth through fenton chemistry. (2010) (41)
- Cell surface glycoproteomic analysis of prostate cancer-derived PC-3 cells. (2011) (41)
- Tissue slice grafts of human renal cell carcinoma: an authentic preclinical model with high engraftment rate and metastatic potential. (2014) (41)
- Characterization of human keratinocyte (1981) (39)
- KGF and EGF differentially regulate the phenotype of prostatic epithelial cells. (1996) (39)
- Genetic polymorphisms in the androgen receptor and type II 5 alpha-reductase genes in prostate enlargement. (2001) (39)
- Leptomycin B stabilizes and activates p53 in primary prostatic epithelial cells and induces apoptosis in the LNCaP cell line (2003) (39)
- RRx-001: a systemically non-toxic M2-to-M1 macrophage stimulating and prosensitizing agent in Phase II clinical trials (2017) (39)
- Inhibition of monoamine oxidase A promotes secretory differentiation in basal prostatic epithelial cells. (2008) (37)
- Growth and differentiation of human keratinocytes without a feeder layer or conditioned medium (1980) (37)
- Brefeldin A induces p53-independent apoptosis in primary cultures of human prostatic cancer cells. (2000) (37)
- Cellular biology of prostatic growth factors (1996) (36)
- Characterization of cultured human prostatic epithelial cells by cluster designation antigen expression (2001) (36)
- A Protective Role for Androgen Receptor in Clear Cell Renal Cell Carcinoma Based on Mining TCGA Data (2016) (36)
- Integrated Analysis Reveals Critical Genomic Regions in Prostate Tumor Microenvironment Associated with Clinicopathologic Phenotypes (2012) (36)
- Keratinocyte growth factor: an androgen-regulated mediator of stromal-epithelial interactions in the prostate (2004) (36)
- Human Prostatic Epithelial Cells (2002) (35)
- Nrf2 activity as a potential biomarker for the pan-epigenetic anticancer agent, RRx-001 (2015) (35)
- The immunomodulatory anticancer agent, RRx-001, induces an interferon response through epigenetic induction of viral mimicry (2017) (34)
- Recent advances in the development of animal and cell culture models for prostate cancer research A minireview. (1996) (33)
- Determination of Carbohydrate Structure Recognized by Prostate-specific F77 Monoclonal Antibody through Expression Analysis of Glycosyltransferase Genes* (2014) (32)
- Metabolic response of prostate cancer to nicotinamide phophoribosyltransferase inhibition in a hyperpolarized MR/PET compatible bioreactor (2015) (32)
- S100A10 is a critical mediator of GAS6/AXL-induced angiogenesis in renal cell carcinoma. (2019) (31)
- RRx-001, A novel dinitroazetidine radiosensitizer (2016) (31)
- Transcription factor KLLN inhibits tumor growth by AR suppression, induces apoptosis by TP53/TP73 stimulation in prostate carcinomas, and correlates with cellular differentiation. (2013) (31)
- Transforming growth factor-beta induces growth inhibition and IGF-binding protein-3 production in prostatic stromal cells: abnormalities in cells cultured from benign prostatic hyperplasia tissues. (2000) (30)
- Cabozantinib inhibits tumor growth and metastasis of a patient-derived xenograft model of papillary renal cell carcinoma with MET mutation (2017) (29)
- Tumor-suppression function of transcription factor USF2 in prostate carcinogenesis (2006) (29)
- Anti-tumor and radiosensitization activities of the iron chelator HDp44mT are mediated by effects on intracellular redox status. (2010) (29)
- Cultured stromal cells: An in vitro model of prostatic mesenchymal biology (2000) (29)
- Vitamin D and Prostate Cancer Risk (1999) (29)
- Acid‐activated insulin‐like growth factor binding protein protease activity of Cathepsin D in normal and malignant prostatic epithelial cells and seminal plasma (1997) (29)
- Anti‐Oligomannose Antibodies as Potential Serum Biomarkers of Aggressive Prostate Cancer (2013) (29)
- Methods for metabolic evaluation of prostate cancer cells using proton and 13C HR‐MAS spectroscopy and [3‐13C] pyruvate as a metabolic substrate (2009) (28)
- Re-evaluation of inhibin α subunit as a tumour suppressor in prostate cancer (2004) (28)
- The Alternative Splice Variant of Protein Tyrosine Kinase 6 Negatively Regulates Growth and Enhances PTK6-Mediated Inhibition of β-Catenin (2011) (28)
- Anti-oncogenic and pro-differentiation effects of clorgyline, a monoamine oxidase A inhibitor, on high grade prostate cancer cells (2009) (27)
- Transcript levels of androgen receptor variant AR-V1 or AR-V7 do not predict recurrence in patients with prostate cancer at indeterminate risk for progression. (2012) (27)
- Vitamin D inhibition of the prostaglandin pathway as therapy for prostate cancer. (2007) (27)
- Non-Invasive Differentiation of Benign Renal Tumors from Clear Cell Renal Cell Carcinomas Using Clinically Translatable Hyperpolarized 13C Pyruvate Magnetic Resonance (2016) (27)
- Actions Of Vitamin D, Analogs on Human Prostate Cancer Cell Lines: Comparison with (1995) (26)
- Keratin 19 in the adult human prostate: tissue and cell culture studies (1996) (26)
- Establishment and serial passage of cell cultures derived from LuCaP xenografts (2013) (26)
- Rationale for combination ketoconazole/ vitamin D treatment of prostate cancer. (2001) (24)
- Workgroup 2: Human xenograft models of prostate cancer (1998) (24)
- The Elevated Expression of a Mismatch Repair Protein Is a Predictor for Biochemical Recurrence After Radical Prostatectomy (2009) (22)
- Elevated Expression of Inhibin α in Prostate Cancer (2004) (21)
- Simian virus 40-, but not human papillomavirus-, transformation of prostatic epithelial cells results in loss of growth-inhibition by 1,25-dihydroxyvitamin D-3. (1996) (21)
- The role of the Sertoli cell in active immunosuppression in the human testis. (1996) (21)
- Darinaparsin: Solid Tumor Hypoxic Cytotoxin and Radiosensitizer (2012) (21)
- Suramin, hydrocortisone, and retinoic acid modify inhibitory effects of 1,25-dihydroxyvitamin D(3) on prostatic epithelial cells. (1995) (20)
- Oxidative 3alpha-hydroxysteroid dehydrogenase activity of human type 10 17beta-hydroxysteroid dehydrogenase. (2003) (20)
- Development of a realistic in vivo bone metastasis model of human renal cell carcinoma (2014) (20)
- Patient-derived tissue slice grafts accurately depict response of high-risk primary prostate cancer to androgen deprivation therapy (2013) (20)
- Molecular targets of doxazosin in human prostatic stromal cells (2005) (19)
- Parathyroid hormone‐related protein is not an autocrine growth factor for normal prostatic epithelial cells (1997) (19)
- Vitamin D and prostate cancer. (1995) (19)
- Growth of prostatic epithelial and stromal cells in vitro. (2003) (19)
- Re-evaluation of inhibin alpha subunit as a tumour suppressor in prostate cancer. (2004) (18)
- Comparative gene and protein expression in primary cultures of epithelial cells from benign prostatic hyperplasia and prostate cancer. (2005) (18)
- Expression of prostatic factors measured by reverse transcription polymerase chain reaction in human papillomavirus type 18 deoxyribonucleic acid immortalized prostate cell lines. (1998) (17)
- Association of Prostate-Specific Antigen Promoter Genotype with Clinical and Histopathologic Features of Prostate Cancer (2008) (17)
- Growth responses of normal, benign hyperplastic, and malignant human prostatic epithelial cells in vitro to cholera toxin, pituitary extract, and hydrocortisone. (1986) (17)
- 15 – The Male Reproductive System: Prostatic Cell Lines (1994) (17)
- High Resolution Regional Elasticity Mapping of the Human Prostate (2007) (16)
- PR1--a monoclonal antibody that reacts with an antigen on the surface of normal and malignant prostate cells. (1993) (16)
- Potentiation of the growth-inhibitory effects of vitamin D in prostate cancer by genistein. (2007) (16)
- Role of prostatic basal cells in the regulation and suppression of human prostate cancer cells. (1996) (15)
- Induced Pluripotency of Human Prostatic Epithelial Cells (2013) (15)
- Rockets, radiosensitizers, and RRx-001: an origin story part I. (2016) (15)
- PROSTATE SPECIFIC ANTIGEN CLEAVES PARATHYROID HORMONE- PTHrP-STIMULATED cAMP ACCUMULATION IN MOUSE OSTEOBLASTS RELATED PROTEIN IN THE PTH-LIKE DOMAIN: INACTIVATION OF (1996) (15)
- Spheroid culture of LuCaP 136 patient-derived xenograft enables versatile preclinical models of prostate cancer (2016) (15)
- Characterization of human keratinocyte X HeLa somatic cell hybrids. (1981) (15)
- Culture of prostatic epithelial cells from ultrasound‐guided needle biopsies (1991) (15)
- Elevated expression of inhibin alpha in prostate cancer. (2004) (14)
- induced Growth Inhibition 325-Hydroxyvitamin D Cells Correlates with Decreased Susceptibility to-hydroxylase Activity in Human Prostate Cancer α Reduced 1 Updated (2001) (14)
- Keratin Protein In Human Prostatic Tissue and Cell Culture (1985) (14)
- Loss of response to epidermal growth factor and retinoic acid accompanies the transformation of human prostatic epithelial cells to tumorigenicity with v-Ki-ras. (1997) (14)
- Spheroid culture of LuCaP 147 as an authentic preclinical model of prostate cancer subtype with SPOP mutation and hypermutator phenotype. (2014) (14)
- Stiffness mapping prostate biopsy samples using a tactile sensor (2011) (13)
- Clonal growth characteristics of adult human prostatic epithelial cells (1988) (13)
- Epigenetic repression of transcription by the Vitamin D3 receptor in prostate cancer cells (2004) (12)
- Overview consensus statement. (2001) (12)
- Stepwise genetic changes associated with progression of nontumorigenic HPV-18 immortalized human prostate cancer-derived cell line to a malignant phenotype. (2000) (12)
- Oncogenes: a review with relevance to cancers of the urogenital tract. (1986) (12)
- Altered growth-regulation of prostatic epithelial-cells by human papillomavirus-induced transformation. (1995) (11)
- Defined medium for normal adult human prostatic stromal cells (1998) (11)
- Activated Ki-ras oncogene in human prostatic adenocarcinoma. (1987) (10)
- Recent Advances in the Development of Animal and Cell Culture Models for Prostate Cancer Research (1996) (10)
- Radioprotection and cell cycle arrest of intestinal epithelial cells by darinaparsin, a tumor radiosensitizer. (2013) (10)
- Human papilloma virus type 18 DNA immortalized cell lines from the human prostate epithelium. (1994) (9)
- miR-22 Regulates Invasion, Gene Expression and Predicts Overall Survival in Patients with Clear Cell Renal Cell Carcinoma (2019) (9)
- Abstract 3515: RRx-001: A double action systemically non-toxic epigenetic agent for cancer therapy (2015) (8)
- Endoscopic detection of cancer with lensless radioluminescence imaging and machine vision (2016) (8)
- Altered growth regulation and loss of response to retinoic acid accompany tumorigenic transformation of prostatic cells. (1999) (8)
- Elevated Tumor Lactate and Efflux in High-grade Prostate Cancer demonstrated by Hyperpolarized 13C Magnetic Resonance Spectroscopy of Prostate Tissue Slice Cultures (2020) (8)
- Resistance to Androgen Deprivation Leads to Altered Metabolism in Human and Murine Prostate Cancer Cell and Tumor Models (2021) (8)
- A spliced form of CD44 expresses the unique glycan that is recognized by the prostate cancer specific antibody F77 (2017) (8)
- Basic science of hormonal therapy for prostate cancer. (2001) (7)
- Abstract C181: RRx-001 combined with anti-PD-L1 antibody increases the complete response rate in a preclinical myeloma model (2015) (7)
- SU086, an inhibitor of HSP90, impairs glycolysis and represents a treatment strategy for advanced prostate cancer (2022) (7)
- Insulin-like growth factor 1 in relation to prostate cancer and benign prostatic hyperplasia. (1998) (7)
- Serial propagation of adult human prostatic epithelial cells with cholera toxin (1984) (7)
- Silencing of π‐class glutathione S‐transferase in MDA PCa 2a and MDA PCa 2b cells (2002) (7)
- MAP3K7 Loss Drives Enhanced Androgen Signaling and Independently Confers Risk of Recurrence in Prostate Cancer with Joint Loss of CHD1 (2021) (6)
- Erratum: Expression and characterization of recombinant type 2 3α- hydroxysteroid dehydrogenase (HSD) from human prostate: Demonstration of bifunctional 3α17β-hsd activity and cellular distribution: (Molecular Endocrinology (1997) 11 (1997-1984)) (1998) (6)
- NMR quantification of lactate production and efflux and glutamate fractional enrichment in living human prostate biopsies cultured with [1,6‐13C2]glucose (2019) (6)
- Serum Mac‐2BP does not distinguish men with high grade, large volume prostate cancer from men with benign prostatic hyperplasia (2011) (5)
- Oncogene expression. (1987) (5)
- Searching for suppressor genes in prostate cancer. (1991) (5)
- INK 4 A Mediates Cyclin Dependent Kinase 4 and 6 Inhibition in Senescent Prostatic Epithelial Cells 1 (2000) (5)
- SMAD 3 Represses Androgen Receptor-mediated Transcription 1 (2001) (5)
- Prostatic expression of hensin, a protein implicated in epithelial terminal differentiation (2001) (5)
- Human prostatic epithelial and stromal cell lines and strains. (1996) (4)
- Transformation‐altered growth factor responses of human prostatic epithelial cells (1995) (4)
- Molecular biology of proto‐oncogenes in genitourinary cancers (1987) (4)
- A tissue graft model of DNA damage response in the normal and malignant human prostate. (2014) (4)
- 142 The role of hypoxia, p53, and apoptosis in human cervical carcinoma pathogenesis (1997) (3)
- Author response: Tumor microenvironment derived exosomes pleiotropically modulate cancer cell metabolism (2015) (3)
- 158 PRE-CLINICAL TRIAL OF A NEW DUAL MTOR INHIBITOR : INK128 FOR RENAL CELL CARCINOMA (2013) (3)
- Epithelial Cell Culture (2002) (3)
- A note on improved statistical approaches to account for pseudoprogression (2018) (3)
- Animal Models and Their Role in Imaging-Assisted Co-Clinical Trials (2023) (2)
- International Congress on Hormonal Steroids and Hormones and Cancer The role of vitamin D and retinoids in controlling prostate cancer progression (2003) (2)
- Abstract 906: Molecular imaging of RRx-001-induced oxidative stress in Nrf2-luciferase expressing SCC VII tumors in mice (2014) (2)
- Identifying prostate cancer biomarkers by profiling glycoproteins in human prostate tissue (591.6) (2014) (2)
- Nuclear KLLN expression associates with improved relapse-free survival for prostate carcinoma. (2014) (2)
- In vitro multistep human prostate epithelial cell models for studying prostate carcinogenesis (1995) (2)
- A spliced form of CD 44 expresses the unique glycan that is recognized by the prostate cancer specific antibody F 77 (2018) (1)
- Identification of Epigenetic Changes in Prostate Cancer using Induced Pluripotent Stem Cells (2014) (1)
- Prostatic Growth Factors, Cancer, and Steroid Hormone Activity (1996) (1)
- Prostatitis and Urethritis (1999) (1)
- Tissue Specimens Are Reduced in Cultured Human Prostate Cancer Cells and Retinol Metabolism and Lecithin:Retinol Acyltransferase Levels (2013) (1)
- Patient-derived tissue slice grafts accurately depict response of high-risk primary prostate cancer to androgen deprivation therapy (2013) (1)
- 975 Pre-clinical trial of a new dual mTOR inhibitor: INK128 for renal cell carcinoma (2013) (1)
- Abstract 608: Comprehensive drug testing of patient-derived conditionally reprogrammed cells from castration-resistant prostate cancer (2016) (1)
- The immunomodulatory anticancer agent, RRx-001, induces an interferon response through epigenetic induction of viral mimicry (2017) (1)
- Multiparametric Magnetic Resonance Imaging and Metabolic Characterization of Patient-Derived Xenograft Models of Clear Cell Renal Cell Carcinoma (2022) (1)
- Expression of the leukocyte chemoattractant chemerin in human prostate tumors. (2015) (1)
- 506 Darinaparsin (ZIO-101) is a novel cytotoxic and radiosensitizing agent for prostate cancer (2010) (1)
- The controversial role and therapeutic development of the m6A demethylase FTO in renal cell carcinoma (2022) (1)
- Abstract PR2: Optimization and applications of a tissue slice culture model of the normal and malignant human prostate (2012) (0)
- Award Number: W81XWH-10-1-0240 TITLE: Identification of Epigenetic Changes in Prostate Cancer using Induced Pluripotent Stem Cells (2011) (0)
- Development of a realistic in vivo bone metastasis model of human renal cell carcinoma (2014) (0)
- A Chemical Glycoproteomics Platform To study the Human Prostate Secretome (2016) (0)
- Title: Integrated Analysis Reveals Critical Genomic Regions in Prostate Tumor- Microenvironment Associated with Clinico-pathologic Phenotypes (2012) (0)
- Analysis of somatic cell hybrids derived from normal human prostatic epithelial cells fused with HeLa cells (1990) (0)
- Abstract A3: A tumorgraft model of castration-resistant primary prostate cancer (2012) (0)
- Vitamin D Receptor Start Codon Polymorphism ( FokI ) and Prostate Cancer Progression 1 (2003) (0)
- 761 Establishing primary renal cancer cell cultures in vitro linked to a corresponding orthotopic in vivo model (2013) (0)
- 304 A PATIENT-DERIVED TUMORGRAFT MODEL FOR RENAL CELL CARCINOMA (2013) (0)
- Discovery of Hyperpolarized Molecular Imaging Biomarkers in a Novel Prostate Tissue Slice Culture Model (2011) (0)
- Darinaparsin: Tumor Radiosensitizer That Radioprotects Intestinal Epithelium (2012) (0)
- MP29-06 IQGAP1 EXPRESSION AND SURVIVAL IN CLEAR CELL RENAL CELL CARCINOMA (2014) (0)
- Abstract B32: Patient-derived tissue slice grafts of high-risk primary prostate cancer: An authentic preclinical model for synthetic lethality-based therapy (2013) (0)
- Expression of CCL5 (RANTES) and its receptors in prostate cancer (2005) (0)
- Origin of Prostate Cancer-Associated Stroma: Epithellal Mesenchymal Transition (EMT) (2006) (0)
- TheCurrent State of Preclinical ProstateCancerAnimalModels (2008) (0)
- Oral Presentations 7 (2004) (0)
- 864 MONOAMINE OXIDASE A: A NEW CANDIDATE THERAPEUTIC TARGET FOR ADVANCED PROSTATE CANCER (2010) (0)
- Abstract B207: Darinaparsin is an anti-solid tumor cytotoxin in vivo. (2011) (0)
- Nutritional Genomics in Cancer Processes Pathways Mediating the Growth-Inhibitory Actions of Vitamin D in Prostate Cancer 1 (2003) (0)
- 2210 HPV E6 and E7 in hypoxia mediated tumorigenesis in cervical epithelial cells (1996) (0)
- 140 Orthotopic xenografts using LuCaP136 spheroid cultures provide a versatile preclinical model of prostate cancer (2016) (0)
- Abstract 319: Expanding the experimental potential of a novelex vivomodel for primary human prostate cancer. (2013) (0)
- Development of Methodology to Maintain Primary Cultures of Normal and Malignant Human Prostatic Epithelial Cells In Vivo (2006) (0)
- Abstract 4358: The immunomodulatory anticancer agent RRx-001 induces a vaccine-like interferon response through epigenetic induction of viral mimicry (2017) (0)
- Abstract C129: Darinaparsin sensitizes solid tumors but not normal tissues to radiation. (2011) (0)
- 163 Generation of patient-derived three-dimensional spheroid cultures for in vitro studies on localized prostate cancer (2015) (0)
- A Unifying Theory of Prostate Cancer (2000) (0)
- GADD45α and MAPK-APK2 are epigenetically repressed VDR target genes in prostate cancer (2003) (0)
- INSULIN-LIKE GROWTH FACTOR 1 IN RELATION TO PROSTATE CANCER AND BENIGN PROSTATIC HYPERPLASIA. AUTHORS' REPLY (1998) (0)
- Spheroid culture of LuCaP 136 patient-derived xenograft enables versatile preclinical models of prostate cancer (2016) (0)
- Cancer Therapy : Preclinical Darinaparsin : Solid Tumor Hypoxic Cytotoxin and Radiosensitizer (2012) (0)
- Abstract 3594: Tumor microenvironment derived exosomes regulate prostate cancer metabolism (2014) (0)
- Current concepts of oncogenes in prostate cancer (1998) (0)
- Abstract B37: Patient-derived tissue culture model systems of renal cell carcinoma for development of clinically translatable metabolic biomarkers (2014) (0)
- Development of a Novel Tissue Slice Culture Model of Human Prostate Cancer (2004) (0)
- Abstract 4916: Improved statistical approaches that account for pseudoprogression in preclinical studies of RRx-001 with immunotherapies (2016) (0)
- A Chemical Glycoproteomics Platform Applied to Human Prostate Cancer (2015) (0)
- Cells With Unique Properties in Prostate Cancer-Associated Storma Are Mesenchymal Stem Cells (2007) (0)
- Therapie du cancer et medicaments associes (2005) (0)
- 988: Urine Survivin Levels in Bladder Cancer Patients Using Enzyme-Linked Immunoassay (2006) (0)
- TITLE: Cells with Unique Properties in Prostate Cancer-Associated Storma Are Mesenchymal Stem Cells (2007) (0)
- SU086, a New Inhibitor of HSP90, Impairs Glycolysis and Represents a New Treatment Strategy for Advanced Prostate Cancer (2021) (0)
- 188 Development of a realistic in vivo bone metastasis model for human renal cell carcinoma (2014) (0)
- The Biological and Clinical Significance of Androgen Receptor Variants (2014) (0)
- Vol. 35, 1999 (1999) (0)
- Frequency and Pattern of Karyotypic Abnormalities in Human Prostate Cancer1 (2006) (0)
- Subject Index Vol. 35, 1999 (1999) (0)
- Sensitization of neuroendocrine prostate cancer by RRx-001. (2018) (0)
- Abstract B9: Mouse model of primary human renal cell carcinoma metastasis to bone (2013) (0)
- Retinoic acid stimulation of gelatinase a (MMP-2) and matrilysin (MMP-7) expression in human prostate epithelial cells (2003) (0)
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What Schools Are Affiliated With Donna M. Peehl?
Donna M. Peehl is affiliated with the following schools:
