Douglas Easton

Q: What Schools Are Affiliated With Douglas Easton

Douglas Easton is affiliated with the following schools: University of Oxford, University of Melbourne, University of Edinburgh, Technical University of Munich, Karolinska Institute, Leiden University, University of Southampton, University of Cambridge, University of Calgary, Aarhus University, Medical University of Vienna, Queensland University of Technology, Institute of Cancer Research

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Douglas Easton

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#82

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Douglas Easton

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#2929

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#4564

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#242

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Why Is Douglas Easton Influential?

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According to Wikipedia, Douglas F. Easton FMedSci is a British epidemiologist who conducts research on the genetics of human cancers. He is Professor of Genetic Epidemiology and Centre for Cancer Genetic Epidemiology at the University of Cambridge. He founded Cambridge's Cancer Research UK Genetic Epidemiology Unit in 1995, and was a Principal Research Fellow there from 2001 to 2011. He is a Professorial Fellow of Homerton College, Cambridge.

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Douglas Easton's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls (2007) (9208)
Tamoxifen for early breast cancer: an overview of the randomised trials (1998) (3764)
Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case Series unselected for family history: a combined analysis of 22 studies. (2003) (3543)
Patterns of somatic mutation in human cancer genomes (2007) (3038)
Genetic heterogeneity and penetrance analysis of the BRCA1 and BRCA2 genes in breast cancer families. The Breast Cancer Linkage Consortium. (1998) (2846)
Identification of the breast cancer susceptibility gene BRCA2 (1995) (2451)
Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease (2004) (2367)
Genome-wide association study identifies novel breast cancer susceptibility loci (2007) (2351)
Risks of cancer in BRCA1-mutation carriers (1994) (1862)
International network of cancer genome projects (2010) (1839)
Breast and ovarian cancer incidence in BRCA1-mutation carriers. Breast Cancer Linkage Consortium. (1995) (1666)
Risks of Breast, Ovarian, and Contralateral Breast Cancer for BRCA1 and BRCA2 Mutation Carriers (2017) (1644)
The landscape of cancer genes and mutational processes in breast cancer (2012) (1610)
Identification of the breast cancer susceptibility gene BRCA2 (1996) (1451)
Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants (2007) (1421)
The Evolutionary History of Lethal Metastatic Prostate Cancer (2015) (1150)
Genetic linkage analysis in familial breast and ovarian cancer: results from 214 families. The Breast Cancer Linkage Consortium. (1993) (1135)
Cancer Incidence in BRCA1 mutation carriers. (2002) (1113)
Large-scale genotyping identifies 41 new loci associated with breast cancer risk (2013) (1063)
Screening with magnetic resonance imaging and mammography of a UK population at high familial risk of breast cancer: a prospective multicentre cohort study (MARIBS) (2005) (1061)
Subtyping of Breast Cancer by Immunohistochemistry to Investigate a Relationship between Subtype and Short and Long Term Survival: A Collaborative Analysis of Data for 10,159 Cases from 12 Studies (2010) (1025)
Systematic population-based assessment of cancer risk in first-degree relatives of cancer probands. (1994) (1024)
PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility gene (2007) (1005)
Association analysis identifies 65 new breast cancer risk loci (2017) (922)
Interim analysis of the incidence of breast cancer in the Royal Marsden Hospital tamoxifen randomised chemoprevention trial (1998) (921)
Prevalence of BRCA1 and BRCA2 gene mutations in patients with early-onset breast cancer. (1999) (876)
Multiple newly identified loci associated with prostate cancer susceptibility (2008) (866)
Low-penetrance susceptibility to breast cancer due to CHEK2*1100delC in noncarriers of BRCA1 or BRCA2 mutations (2002) (860)
The pathology of familial breast cancer: predictive value of immunohistochemical markers estrogen receptor, progesterone receptor, HER-2, and p53 in patients with mutations in BRCA1 and BRCA2. (2002) (842)
Polygenic susceptibility to breast cancer and implications for prevention (2002) (840)
Common Genetic Variation In Cellular Transport Genes and Epithelial Ovarian Cancer (EOC) Risk (2015) (838)
Sequence variant classification and reporting: recommendations for improving the interpretation of cancer susceptibility genetic test results (2008) (809)
Cancer risks for BRCA1 and BRCA2 mutation carriers: results from prospective analysis of EMBRACE. (2013) (802)
Gene-panel sequencing and the prediction of breast-cancer risk. (2015) (747)
Truncating mutations in the Fanconi anemia J gene BRIP1 are low-penetrance breast cancer susceptibility alleles (2006) (733)
ATM mutations that cause ataxia-telangiectasia are breast cancer susceptibility alleles (2006) (728)
Genome-wide association study identifies five new breast cancer susceptibility loci (2010) (716)
Risk of lymphoedema following the treatment of breast cancer (1986) (709)
Multifactorial analysis of differences between sporadic breast cancers and cancers involving BRCA1 and BRCA2 mutations. (1998) (700)
Family history and the risk of breast cancer: A systematic review and meta‐analysis (1997) (672)
Prediction of BRCA1 Status in Patients with Breast Cancer Using Estrogen Receptor and Basal Phenotype (2005) (667)
Germline BRCA mutations are associated with higher risk of nodal involvement, distant metastasis, and poor survival outcomes in prostate cancer. (2013) (619)
A common coding variant in CASP8 is associated with breast cancer risk (2007) (591)
A systematic, large-scale resequencing screen of X-chromosome coding exons in mental retardation (2009) (582)
A systematic review of genetic polymorphisms and breast cancer risk. (1999) (577)
Estimates of the gene frequency of BRCA1 and its contribution to breast and ovarian cancer incidence. (1995) (576)
Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes (2018) (559)
MicroRNA Related Polymorphisms and Breast Cancer Risk (2014) (557)
Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array (2012) (550)
Association between BRCA1 and BRCA2 mutations and survival in women with invasive epithelial ovarian cancer. (2012) (544)
Associations of breast cancer risk factors with tumor subtypes: a pooled analysis from the Breast Cancer Association Consortium studies. (2011) (536)
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer (2013) (534)
A comprehensive model for familial breast cancer incorporating BRCA1, BRCA2 and other genes (2002) (528)
Cancer risks and mortality in heterozygous ATM mutation carriers. (2005) (521)
Rare and low-frequency coding variants alter human adult height (2016) (511)
Parent-of-origin specific allelic associations among 106 genomic loci for age at menarche (2014) (511)
Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci (2018) (509)
Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer (2015) (502)
Association studies for finding cancer-susceptibility genetic variants (2004) (502)
Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2 (2009) (502)
Variation in cancer risks, by mutation position, in BRCA2 mutation carriers. (2001) (499)
Germline mutations of the BRCA1 gene in breast and ovarian cancer families provide evidence for a genotype–phenotype correlation (1995) (490)
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies (2010) (477)
Prediction of Breast Cancer Risk Based on Profiling With Common Genetic Variants (2015) (471)
Somatic mutations of the protein kinase gene family in human lung cancer. (2005) (468)
Variation of risks of breast and ovarian cancer associated with different germline mutations of the BRCA2 gene (1997) (465)
Prospective randomised trial of single and multifraction radiotherapy schedules in the treatment of painful bony metastases. (1986) (447)
Pathology of Breast and Ovarian Cancers among BRCA1 and BRCA2 Mutation Carriers: Results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA) (2011) (447)
The BOADICEA model of genetic susceptibility to breast and ovarian cancer (2004) (444)
CHEK2*1100delC and susceptibility to breast cancer: a collaborative analysis involving 10,860 breast cancer cases and 9,065 controls from 10 studies. (2004) (442)
Allele losses in the region 17q12–21 in familial breast and ovarian cancer involve the wild–type chromosome (1992) (436)
A linked genetic marker for multiple endocrine neoplasia type 2A on chromosome 10 (1987) (433)
Identification of seven new prostate cancer susceptibility loci through a genome-wide association study (2009) (428)
Variants in DNA double-strand break repair genes and breast cancer susceptibility. (2002) (417)
A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer (2014) (416)
Floating absolute risk: an alternative to relative risk in survival and case-control analysis avoiding an arbitrary reference group. (1991) (415)
A novel recurrent mutation in MITF predisposes to familial and sporadic melanoma (2011) (414)
Genome-wide association studies identify four ER negative–specific breast cancer risk loci (2013) (411)
Genome-Wide Association Study in BRCA1 Mutation Carriers Identifies Novel Loci Associated with Breast and Ovarian Cancer Risk (2013) (405)
The BOADICEA model of genetic susceptibility to breast and ovarian cancers: updates and extensions (2008) (403)
A hypermutation phenotype and somatic MSH6 mutations in recurrent human malignant gliomas after alkylator chemotherapy. (2006) (401)
Analysis of the Genetic Phylogeny of Multifocal Prostate Cancer Identifies Multiple Independent Clonal Expansions in Neoplastic and Morphologically Normal Prostate Tissue (2015) (399)
Integrated evaluation of DNA sequence variants of unknown clinical significance: application to BRCA1 and BRCA2. (2004) (397)
Genetic susceptibility to breast cancer (2010) (394)
Cancer risks in two large breast cancer families linked to BRCA2 on chromosome 13q12-13. (1997) (393)
Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer. (2015) (390)
Heterogeneity of Breast Cancer Associations with Five Susceptibility Loci by Clinical and Pathological Characteristics (2008) (390)
Genetic Linkage Analysis in Familial Breast and Ovarian Cancer: Results from 214 Families (2006) (384)
An analysis of variation in expression of neurofibromatosis (NF) type 1 (NF1): evidence for modifying genes. (1993) (381)
Patterns of somatic structural variation in human cancer genomes (2020) (377)
Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer (2013) (377)
Influence of cytokine gene polymorphisms on the development of prostate cancer. (2002) (373)
ATM mutations and phenotypes in ataxia-telangiectasia families in the British Isles: expression of mutant ATM and the risk of leukemia, lymphoma, and breast cancer. (1998) (371)
Breast-cancer risk in families with mutations in PALB2. (2014) (367)
RAD51B in Familial Breast Cancer (2016) (366)
Two percent of men with early-onset prostate cancer harbor germline mutations in the BRCA2 gene. (2003) (365)
Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk (2017) (359)
Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer (2014) (358)
A systematic genetic assessment of 1,433 sequence variants of unknown clinical significance in the BRCA1 and BRCA2 breast cancer-predisposition genes. (2007) (358)
Specific morphological features predictive for the basal phenotype in grade 3 invasive ductal carcinoma of breast (2006) (357)
A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor–negative breast cancer in the general population (2010) (357)
Multiple loci with different cancer specificities within the 8q24 gene desert. (2008) (357)
Polymorphisms associated with circulating sex hormone levels in postmenopausal women. (2005) (355)
Genome-wide association studies in cancer. (2008) (352)
GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer (2013) (350)
How many more breast cancer predisposition genes are there? (1999) (349)
A screen of the complete protein kinase gene family identifies diverse patterns of somatic mutations in human breast cancer (2005) (341)
A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24 (2010) (341)
BRCA2 is a moderate penetrance gene contributing to young-onset prostate cancer: implications for genetic testing in prostate cancer patients (2011) (337)
Basal-like grade III invasive ductal carcinoma of the breast: patterns of metastasis and long-term survival (2007) (331)
Variants near DMRT1, TERT and ATF7IP are associated with testicular germ cell cancer (2010) (329)
BOADICEA: a comprehensive breast cancer risk prediction model incorporating genetic and nongenetic risk factors (2019) (325)
Breast Cancer Risk Genes - Association Analysis in More than 113,000 Women. (2020) (322)
A genome-wide association study of testicular germ cell tumor (2009) (322)
Haplotype and phenotype analysis of nine recurrent BRCA2 mutations in 111 families: results of an international study. (1998) (316)
Multiple loci on 8q24 associated with prostate cancer susceptibility (2009) (316)
Evidence for further breast cancer susceptibility genes in addition to BRCA1 and BRCA2 in a population‐based study (2001) (314)
Large-scale genomic analyses link reproductive ageing to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair (2015) (308)
A common variant at the TERT-CLPTM1L locus is associated with estrogen receptor–negative breast cancer (2011) (306)
A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2 (2009) (305)
Models of genetic susceptibility to breast cancer (2006) (303)
A Transforming Growth Factorβ1 Signal Peptide Variant Increases Secretion in Vitro and Is Associated with Increased Incidence of Invasive Breast Cancer (2003) (303)
Positional cloning of the Fanconi anaemia group A gene (1996) (296)
Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study (2011) (295)
Genome-wide association analysis identifies three new breast cancer susceptibility loci (2012) (291)
The genetics of breast and ovarian cancer. (1995) (290)
Pathology of Ovarian Cancers in BRCA1 and BRCA2 Carriers (2004) (287)
Discovery of common and rare genetic risk variants for colorectal cancer (2018) (279)
Population-based estimate of the average age-specific cumulative risk of breast cancer for a defined set of protein-truncating mutations in BRCA1 and BRCA2. Australian Breast Cancer Family Study. (1999) (277)
Effect of BRCA Mutations on Metastatic Relapse and Cause-specific Survival After Radical Treatment for Localised Prostate Cancer. (2015) (276)
RAD51 135G-->C modifies breast cancer risk among BRCA2 mutation carriers: results from a combined analysis of 19 studies. (2007) (276)
Germline BRCA1 mutations increase prostate cancer risk (2012) (273)
Lifetime risks of common cancers among retinoblastoma survivors. (2004) (271)
The Genetic Epidemiology of Breast Cancer Genes (2004) (269)
The OncoArray Consortium: A Network for Understanding the Genetic Architecture of Common Cancers (2016) (267)
Common variants at 19p13 are associated with susceptibility to ovarian cancer (2010) (262)
Analysis and meta-analysis of two serotonin transporter gene polymorphisms in bipolar and unipolar affective disorders. (1998) (259)
Polygenic inheritance of breast cancer: Implications for design of association studies (2003) (256)
Consistent loss of the wild type allele in breast cancers from a family linked to the BRCA2 gene on chromosome 13q12-13. (1995) (256)
Germline BRCA mutation and outcome in young-onset breast cancer (POSH): a prospective cohort study (2018) (256)
Risk of cutaneous melanoma associated with pigmentation characteristics and freckling: Systematic overview of 10 case‐control studies (1995) (255)
Genome-wide association study identifies three new melanoma susceptibility loci (2011) (252)
Localization to Xq27 of a susceptibility gene for testicular germ-cell tumours (2000) (251)
Linkage of a nasopharyngeal carcinoma susceptibility locus to the HLA regions (1990) (250)
Genome-wide association study of renal cell carcinoma identifies two susceptibility loci on 2p21 and 11q13.3 (2011) (246)
Contribution of BRCA1 mutations to ovarian cancer. (1997) (246)
Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer (2017) (244)
High prevalence of the 999del5 mutation in icelandic breast and ovarian cancer patients. (1996) (239)
Common breast cancer-predisposition alleles are associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers. (2008) (238)
A prospective randomised trial of 4 Gy or 8 Gy single doses in the treatment of metastatic bone pain. (1992) (236)
Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk (2012) (234)
A systematic review and meta‐analysis of family history and risk of ovarian cancer (1998) (233)
A germline mutation in the androgen receptor gene in two brothers with breast cancer and Reifenstein syndrome (1992) (233)
The genetic epidemiology of prostate cancer and its clinical implications (2014) (232)
Using human genetics to understand the disease impacts of testosterone in men and women (2020) (228)
Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers. (2013) (225)
Pregnancies, breast-feeding, and breast cancer risk in the International BRCA1/2 Carrier Cohort Study (IBCCS). (2006) (224)
Ovarian cancer risk in BRCA1 carriers is modified by the HRAS1 variable number of tandem repeat (VNTR) locus (1996) (222)
A prospective study of neurofibromatosis type 1 cancer incidence in the UK (2006) (219)
Exposure to diagnostic radiation and risk of breast cancer among carriers of BRCA1/2 mutations: retrospective cohort study (GENE-RAD-RISK) (2012) (214)
Breast and Ovarian Cancer Incidence in BRCA I -Mutation Carriers (2007) (213)
Evaluation of Polygenic Risk Scores for Breast and Ovarian Cancer Risk Prediction in BRCA1 and BRCA2 Mutation Carriers (2017) (211)
The Y deletion gr/gr and susceptibility to testicular germ cell tumor. (2005) (208)
Mutational signatures of ionizing radiation in second malignancies (2016) (207)
BOADICEA breast cancer risk prediction model: updates to cancer incidences, tumour pathology and web interface (2013) (206)
Mutational spectrum in a worldwide study of 29,700 families with BRCA1 or BRCA2 mutations (2018) (206)
Genetically Predicted Body Mass Index and Breast Cancer Risk: Mendelian Randomization Analyses of Data from 145,000 Women of European Descent (2016) (205)
Risk models for familial ovarian and breast cancer (2000) (204)
Bone marrow micrometastases in primary breast cancer: prognostic significance after 6 years' follow-up. (1991) (201)
Genetic and histopathologic evaluation of BRCA1 and BRCA2 DNA sequence variants of unknown clinical significance. (2006) (201)
Prophylactic oophorectomy in inherited breast/ovarian cancer families. (1995) (200)
Risk factors for the incidence of breast cancer: do they affect survival from the disease? (2008) (200)
Genome-wide meta-analysis identifies five new susceptibility loci for cutaneous malignant melanoma (2015) (199)
Mutations in CUL4B, which encodes a ubiquitin E3 ligase subunit, cause an X-linked mental retardation syndrome associated with aggressive outbursts, seizures, relative macrocephaly, central obesity, hypogonadism, pes cavus, and tremor. (2007) (199)
Effect of chest X-rays on the risk of breast cancer among BRCA1/2 mutation carriers in the international BRCA1/2 carrier cohort study: a report from the EMBRACE, GENEPSO, GEO-HEBON, and IBCCS Collaborators' Group. (2006) (199)
Genetic evidence and integration of various data sources for classifying uncertain variants into a single model (2008) (198)
Comprehensive molecular characterization of mitochondrial genomes in human cancers (2017) (197)
Common breast cancer susceptibility alleles and the risk of breast cancer for BRCA1 and BRCA2 mutation carriers: implications for risk prediction. (2010) (196)
Cancer Risks Associated With Germline PALB2 Pathogenic Variants: An International Study of 524 Families. (2019) (196)
Risk of cutaneous melanoma associated with a family history of the disease (1995) (196)
Critical assessment of new risk factors for breast cancer: considerations for development of an improved risk prediction model. (2007) (193)
Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure underpinning obesity (2017) (193)
Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium. (2011) (192)
Variation in BRCA1 cancer risks by mutation position. (2002) (189)
HOXB13 is a susceptibility gene for prostate cancer: results from the International Consortium for Prostate Cancer Genetics (ICPCG) (2012) (186)
Predicting the likelihood of carrying a BRCA1 or BRCA2 mutation: validation of BOADICEA, BRCAPRO, IBIS, Myriad and the Manchester scoring system using data from UK genetics clinics (2008) (186)
Identification of Novel Genetic Markers of Breast Cancer Survival (2015) (185)
The extent of linkage disequilibrium in four populations with distinct demographic histories. (2000) (185)
Genome-wide association study identifies new prostate cancer susceptibility loci. (2011) (183)
A common variant in BRCA2 is associated with both breast cancer risk and prenatal viability (2000) (183)
A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6q14 and 20q11. (2012) (182)
BRCA1 and BRCA2 mutations in a population-based study of male breast cancer (2001) (179)
IGF1 and IGFBP3 tagging polymorphisms are associated with circulating levels of IGF1, IGFBP3 and risk of breast cancer. (2006) (178)
Haplotype and phenotype analysis of six recurrent BRCA1 mutations in 61 families: results of an international study. (1996) (177)
Effect of germ-line genetic variation on breast cancer survival in a population-based study. (2002) (177)
Polygenes, risk prediction, and targeted prevention of breast cancer. (2008) (176)
Identification of six new susceptibility loci for invasive epithelial ovarian cancer (2014) (176)
Improving reporting standards for polygenic scores in risk prediction studies (2020) (175)
Prognostic factors in stage I non-seminomatous germ-cell testicular tumors managed by orchiectomy and surveillance: implications for adjuvant chemotherapy. (1986) (174)
Interplay between BRCA1 and RHAMM Regulates Epithelial Apicobasal Polarization and May Influence Risk of Breast Cancer (2011) (174)
PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS (2016) (174)
Micrometastases in bone marrow in patients with primary breast cancer: evaluation as an early predictor of bone metastases. (1987) (173)
An international initiative to identify genetic modifiers of cancer risk in BRCA1 and BRCA2 mutation carriers: the Consortium of Investigators of Modifiers of BRCA1 and BRCA2 (CIMBA) (2007) (173)
Familial male breast cancer is not linked to the BRCA1 locus on chromosome 17q (1994) (173)
RISK ESTIMATION AND SCREENING IN FAMILIES OF PATIENTS WITH MEDULLARY THYROID CARCINOMA (1988) (171)
Mutations in the DLG3 gene cause nonsyndromic X-linked mental retardation. (2004) (170)
Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets (2018) (169)
Multiple Novel Prostate Cancer Predisposition Loci Confirmed by an International Study: The PRACTICAL Consortium (2008) (169)
Comprehensive Functional Annotation of 77 Prostate Cancer Risk Loci (2014) (168)
CHEK2 variant I157T may be associated with increased breast cancer risk (2004) (168)
Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer (2013) (167)
Statistical Analysis of Pathogenicity of Somatic Mutations in Cancer (2006) (167)
A weighted cohort approach for analysing factors modifying disease risks in carriers of high‐risk susceptibility genes (2005) (166)
Sibling risks in cancer: clues to recessive or X-linked genes? (2001) (164)
Apolipoprotein E Genetic Variation and Alzheimer’s Disease (1999) (164)
CHEK2*1100delC heterozygosity in women with breast cancer associated with early death, breast cancer-specific death, and increased risk of a second breast cancer. (2012) (164)
Tamoxifen and risk of contralateral breast cancer for BRCA1 and BRCA2 mutation carriers. (2013) (163)
Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction (2021) (163)
A combined genomewide linkage scan of 1,233 families for prostate cancer-susceptibility genes conducted by the international consortium for prostate cancer genetics. (2005) (161)
Mutations in ZDHHC9, which encodes a palmitoyltransferase of NRAS and HRAS, cause X-linked mental retardation associated with a Marfanoid habitus. (2007) (160)
Inherited susceptibility to breast cancer. (1993) (159)
Evidence of Gene–Environment Interactions between Common Breast Cancer Susceptibility Loci and Established Environmental Risk Factors (2013) (159)
Prostate cancer in male BRCA1 and BRCA2 mutation carriers has a more aggressive phenotype (2008) (159)
Androgen receptor polymorphisms: Association with prostate cancer risk, relapse and overall survival (1999) (158)
Population-based family studies in genetic epidemiology (2005) (158)
Association between Common Variation in 120 Candidate Genes and Breast Cancer Risk (2007) (158)
The contributions of breast density and common genetic variation to breast cancer risk. (2015) (156)
Survival in familial, BRCA1-associated, and BRCA2-associated epithelial ovarian cancer. United Kingdom Coordinating Committee for Cancer Research (UKCCCR) Familial Ovarian Cancer Study Group. (1999) (156)
Polygenic susceptibility to prostate and breast cancer: implications for personalised screening (2011) (155)
Age- and Tumor Subtype-Specific Breast Cancer Risk Estimates for CHEK2*1100delC Carriers. (2016) (154)
Common Genetic Variants and Modification of Penetrance of BRCA2-Associated Breast Cancer (2010) (154)
Cancer Risks in A-T Heterozygotes. (1994) (153)
Telomere length in prospective and retrospective cancer case-control studies. (2010) (152)
Cancer risks in A-T heterozygotes. (1994) (152)
Familial cylindromatosis (turban tumour syndrome) gene localised to chromosome 16q12–q13: evidence for its role as a tumour suppressor gene (1995) (152)
Oral contraceptives and breast cancer risk in the international BRCA1/2 carrier cohort study: a report from EMBRACE, GENEPSO, GEO-HEBON, and the IBCCS Collaborating Group. (2007) (151)
Breast and ovarian cancer risks to carriers of the BRCA1 5382insC and 185delAG and BRCA2 6174delT mutations: a combined analysis of 22 population based studies (2005) (149)
Identification of nine new susceptibility loci for testicular cancer, including variants near DAZL and PRDM14 (2013) (149)
A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer (2018) (149)
Variants in CHEK2 other than 1100delC do not make a major contribution to breast cancer susceptibility. (2003) (146)
A genome wide linkage search for breast cancer susceptibility genes (2006) (146)
Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types. (2016) (146)
Genome-wide association study identifies 25 known breast cancer susceptibility loci as risk factors for triple-negative breast cancer. (2014) (145)
Polygenic hazard score to guide screening for aggressive prostate cancer: development and validation in large scale cohorts (2018) (144)
Reproductive and Hormonal Factors, and Ovarian Cancer Risk for BRCA1 and BRCA2 Mutation Carriers: Results from the International BRCA1/2 Carrier Cohort Study (2009) (143)
A transforming growth factorbeta1 signal peptide variant increases secretion in vitro and is associated with increased incidence of invasive breast cancer. (2003) (143)
Prediction of Breast and Prostate Cancer Risks in Male BRCA1 and BRCA2 Mutation Carriers Using Polygenic Risk Scores (2017) (142)
Genome-wide association study identifies a common variant associated with risk of endometrial cancer (2011) (142)
The contribution of germline BRCA1 and BRCA2 mutations to familial ovarian cancer: no evidence for other ovarian cancer-susceptibility genes. (1999) (141)
Cancers of the respiratory tract in mustard gas workers. (1988) (139)
Mammographic density and breast cancer risk in BRCA1 and BRCA2 mutation carriers. (2006) (138)
Common BRCA1 variants and susceptibility to breast and ovarian cancer in the general population. (1997) (136)
Polymorphisms in DNA repair genes and epithelial ovarian cancer risk (2005) (136)
Survival of patients with breast cancer attending Bristol Cancer Help Centre (1990) (135)
Germline Mutation in BRCA1 or BRCA2 and Ten-Year Survival for Women Diagnosed with Epithelial Ovarian Cancer (2014) (135)
Linkage of the gene for the triple A syndrome to chromosome 12q13 near the type II keratin gene cluster. (1996) (135)
The relationship between micrometastases in the bone marrow, histopathologic features of the primary tumor in breast cancer and prognosis. (1988) (135)
Evidence of a Causal Association Between Insulinemia and Endometrial Cancer: A Mendelian Randomization Analysis (2015) (134)
Genome-wide linkage screen for testicular germ cell tumour susceptibility loci. (2006) (133)
Prostate cancer in BRCA2 germline mutation carriers is associated with poorer prognosis (2010) (133)
Association analyses identify 31 new risk loci for colorectal cancer susceptibility (2019) (132)
Cancer mortality in relatives of women with ovarian cancer: The OPCS study (1996) (132)
The contribution of rare variation to prostate cancer heritability (2015) (132)
BRCA Challenge: BRCA Exchange as a global resource for variants in BRCA1 and BRCA2 (2018) (131)
Genetic predisposition to mosaic Y chromosome loss in blood (2019) (131)
The frequency of germ-line mutations in the breast cancer predisposition genes BRCA1 and BRCA2 in familial prostate cancer. The Cancer Research Campaign/British Prostate Group United Kingdom Familial Prostate Cancer Study Collaborators. (2000) (131)
A meta-analysis of genome-wide association studies to identify prostate cancer susceptibility loci associated with aggressive and non-aggressive disease. (2013) (131)
After BRCA1 and BRCA2-what next? Multifactorial segregation analyses of three-generation, population-based Australian families affected by female breast cancer. (2001) (130)
A full-likelihood method for the evaluation of causality of sequence variants from family data. (2003) (130)
No association between androgen or vitamin D receptor gene polymorphisms and risk of breast cancer. (1999) (129)
Linkage analysis of chromosome 1q markers in 136 prostate cancer families. The Cancer Research Campaign/British Prostate Group U.K. Familial Prostate Cancer Study Collaborators. (1998) (128)
Cost-effectiveness of screening with contrast enhanced magnetic resonance imaging vs X-ray mammography of women at a high familial risk of breast cancer (2006) (127)
A genome-wide association scan (GWAS) for mean telomere length within the COGS project: identified loci show little association with hormone-related cancer risk (2013) (125)
Common variants in LSP1, 2q35 and 8q24 and breast cancer risk for BRCA1 and BRCA2 mutation carriers. (2009) (124)
Common breast cancer susceptibility loci are associated with triple-negative breast cancer. (2011) (124)
The ACE gene and Alzheimer's disease susceptibility (2000) (124)
Cancer incidence in BRCA1 mutation carriers (2003) (124)
Immunocytochemical determination of estrogen receptor, progesterone receptor, and 1,25-dihydroxyvitamin D3 receptor in breast cancer and relationship to prognosis. (1991) (123)
Cancer mortality in relatives of women with breast cancer: The OPCS study (1996) (122)
Identification of nine new susceptibility loci for endometrial cancer (2018) (122)
Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170 (2016) (122)
Radiotherapy for stage I seminoma testis: results of treatment and complications. (1986) (121)
Identification of a BRCA2-Specific Modifier Locus at 6p24 Related to Breast Cancer Risk (2013) (120)
The contribution of inherited predisposition to cancer incidence. (1990) (120)
No association between a polymorphism in the steroid metabolism gene CYP17 and risk of breast cancer. (1998) (119)
Mendelian randomization study of adiposity-related traits and risk of breast, ovarian, prostate, lung and colorectal cancer. (2016) (119)
Personalized early detection and prevention of breast cancer: ENVISION consensus statement (2020) (117)
Risk of estrogen receptor-positive and -negative breast cancer and single-nucleotide polymorphism 2q35-rs13387042. (2009) (116)
Where are the prostate cancer genes?—A summary of eight genome wide searches (2003) (115)
19p13.1 is a triple-negative-specific breast cancer susceptibility locus. (2012) (115)
Common germline genetic variation in antioxidant defense genes and survival after diagnosis of breast cancer. (2007) (115)
Common variants in ZNF365 are associated with both mammographic density and breast cancer risk (2011) (114)
Lymphoid tumours and breast cancer in ataxia telangiectasia; substantial protective effect of residual ATM kinase activity against childhood tumours (2011) (113)
FGFR2 variants and breast cancer risk: fine-scale mapping using African American studies and analysis of chromatin conformation. (2009) (113)
The BOADICEA model of genetic susceptibility to breast and ovarian cancers: updates and extensions (2008) (112)
Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation (2014) (112)
DNA Glycosylases Involved in Base Excision Repair May Be Associated with Cancer Risk in BRCA1 and BRCA2 Mutation Carriers (2014) (112)
Reading protocol for dynamic contrast-enhanced MR images of the breast: sensitivity and specificity analysis. (2005) (112)
Genome-wide association studies in common cancers--what have we learnt? (2010) (111)
Genome-wide association study identifies multiple loci associated with both mammographic density and breast cancer risk (2014) (111)
Magnetic resonance imaging screening in women at genetic risk of breast cancer: imaging and analysis protocol for the UK multicentre study (2000) (110)
Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses (2019) (110)
Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31 (2013) (110)
Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1. (2013) (109)
Common Breast Cancer Susceptibility Variants in LSP1 and RAD51L1 Are Associated with Mammographic Density Measures that Predict Breast Cancer Risk (2012) (107)
Height and Breast Cancer Risk: Evidence From Prospective Studies and Mendelian Randomization. (2015) (107)
Life stress, emotional health, and mean telomere length in the European Prospective Investigation into Cancer (EPIC)-Norfolk population study. (2011) (106)
Evaluation of linkage of breast cancer to the putative BRCA3 locus on chromosome 13q21 in 128 multiple case families from the Breast Cancer Linkage Consortium (2002) (106)
Prostate Cancer Risks for Male BRCA1 and BRCA2 Mutation Carriers: A Prospective Cohort Study☆ (2020) (106)
Cardiometabolic effects of genetic upregulation of the interleukin 1 receptor antagonist: a Mendelian randomisation analysis (2015) (106)
A combined analysis of genome-wide association studies in breast cancer (2011) (105)
Identification of 19 new risk loci and potential regulatory mechanisms influencing susceptibility to testicular germ cell tumor (2017) (104)
Targeted prostate cancer screening in men with mutations in BRCA1 and BRCA2 detects aggressive prostate cancer: preliminary analysis of the results of the IMPACT study (2011) (104)
Common variants in the ATM, BRCA1, BRCA2, CHEK2 and TP53 cancer susceptibility genes are unlikely to increase breast cancer risk (2007) (104)
Refined histopathological predictors of BRCA1 and BRCA2mutation status: a large-scale analysis of breast cancer characteristics from the BCAC, CIMBA, and ENIGMA consortia (2014) (103)
Identification of a novel prostate cancer susceptibility variant in the KLK3 gene transcript (2011) (102)
Association of Folate-Pathway Gene Polymorphisms with the Risk of Prostate Cancer: a Population-Based Nested Case-Control Study, Systematic Review, and Meta-analysis (2009) (102)
Novel Common Genetic Susceptibility Loci for Colorectal Cancer (2018) (102)
Common breast cancer susceptibility alleles are associated with tumour subtypes in BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2 (2011) (101)
The clinical and screening age-at-onset distribution for the MEN-2 syndrome. (1989) (101)
Kathleen Cuningham Foundation Consortium For Research Into Familial Breast Cancer (2008) (100)
Assessing interactions between the associations of common genetic susceptibility variants, reproductive history and body mass index with breast cancer risk in the breast cancer association consortium: a combined case-control study (2010) (100)
Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one of which associates with TERT expression (2013) (100)
Mutations in the gene encoding the Sigma 2 subunit of the adaptor protein 1 complex, AP1S2, cause X-linked mental retardation. (2006) (100)
Prevalence of BRCA 1 and BRCA 2 Gene Mutations in Patients With Early-Onset Breast Cancer (1999) (100)
A survey of homozygous deletions in human cancer genomes. (2005) (100)
Relationship between glutathione S-transferase M1, P1 and T1 polymorphisms and early onset prostate cancer. (2001) (98)
Breast cancer genes—what are the real risks? (1997) (98)
Genetic linkage studies map the multiple endocrine neoplasia type 2 loci to a small interval on chromosome 10q11.2. (1993) (98)
Somatic mutations of KIT in familial testicular germ cell tumours (2004) (98)
A genome-wide association study identifies a novel susceptibility locus for renal cell carcinoma on 12p11.23. (2012) (97)
Genetic variants in epigenetic genes and breast cancer risk. (2006) (96)
Localisation of the Fanconi anaemia complementation group A gene to chromosome 16q24.3 (1995) (96)
Radiogenomics: radiobiology enters the era of big data and team science. (2014) (96)
Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer (2016) (95)
The role of genetic breast cancer susceptibility variants as prognostic factors. (2012) (95)
Association of ESR1 gene tagging SNPs with breast cancer risk. (2009) (95)
Tagging single nucleotide polymorphisms in cell cycle control genes and susceptibility to invasive epithelial ovarian cancer. (2007) (94)
A Pilot Study of Compositional Analysis of the Breast and Estimation of Breast Mammographic Density Using Three-Dimensional T1-Weighted Magnetic Resonance Imaging (2008) (94)
Familial site-specific ovarian cancer is linked to BRCA1 on 17q12-21. (1994) (93)
Familial risks of breast cancer (2002) (93)
Genetic variants associated with predisposition to prostate cancer and potential clinical implications (2012) (93)
ATM polymorphisms as risk factors for prostate cancer development (2004) (92)
Assessing the usefulness of a novel MRI-based breast density estimation algorithm in a cohort of women at high genetic risk of breast cancer: the UK MARIBS study (2009) (92)
Inherited genetic susceptibility to breast cancer: the beginning of the end or the end of the beginning? (2013) (92)
Common variants at 12p11, 12q24, 9p21, 9q31.2 and in ZNF365 are associated with breast cancer risk for BRCA1 and/or BRCA2 mutation carriers (2012) (92)
A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease (2016) (92)
Mortality from respiratory cancer and other causes in United Kingdom chromate production workers. (1991) (91)
Common genetic determinants of breast-cancer risk in East Asian women: a collaborative study of 23 637 breast cancer cases and 25 579 controls. (2013) (91)
Consortium analysis of 7 candidate SNPs for ovarian cancer (2008) (91)
Overexpression of RAD51 occurs in aggressive prostatic cancer (2009) (90)
Analysis of the apo E/apo C-I, angiotensin converting enzyme and methylenetetrahydrofolate reductase genes as candidates affecting human longevity. (1997) (90)
Parity and breast cancer risk among BRCA1 and BRCA2 mutation carriers (2006) (90)
Associations of common variants at 1p11.2 and 14q24.1 (RAD51L1) with breast cancer risk and heterogeneity by tumor subtype: findings from the Breast Cancer Association Consortium. (2011) (90)
Implications of polygenic risk-stratified screening for prostate cancer on overdiagnosis (2014) (89)
The rs10993994 Risk Allele for Prostate Cancer Results in Clinically Relevant Changes in Microseminoprotein-Beta Expression in Tissue and Urine (2010) (89)
Polymorphisms in the human aromatase cytochrome P450 gene (CYP19) and breast cancer risk. (2000) (88)
Most common 'sporadic' cancers have a significant germline genetic component. (2014) (88)
Genome-wide association meta-analyses combining multiple risk phenotypes provides insights into the genetic architecture of cutaneous melanoma susceptibility (2020) (87)
Do MDM2 SNP309 and TP53 R72P interact in breast cancer susceptibility? A large pooled series from the breast cancer association consortium. (2007) (87)
Associations among Mammographic Density, Circulating Sex Hormones, and Polymorphisms in Sex Hormone Metabolism Genes in Postmenopausal Women (2006) (87)
Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations. (2016) (87)
Fine-scale mapping of the 5q11.2 breast cancer locus reveals at least three independent risk variants regulating MAP3K1. (2015) (86)
BRCA1 and BRCA2 mutation predictions using the BOADICEA and BRCAPRO models and penetrance estimation in high-risk French-Canadian families (2005) (86)
A risk prediction algorithm based on family history and common genetic variants: application to prostate cancer with potential clinical impact (2011) (86)
Genome-wide association study identifies multiple risk loci for renal cell carcinoma (2017) (86)
Tagging single-nucleotide polymorphisms in antioxidant defense enzymes and susceptibility to breast cancer. (2006) (86)
Joint associations of a polygenic risk score and environmental risk factors for breast cancer in the Breast Cancer Association Consortium. (2018) (86)
Evaluation of BRCA1 and BRCA2 mutation prevalence, risk prediction models and a multistep testing approach in French-Canadian families with high risk of breast and ovarian cancer (2006) (84)
Risk prediction models for familial breast cancer. (2006) (84)
Male breast cancer in BRCA1 and BRCA2 mutation carriers: pathology data from the Consortium of Investigators of Modifiers of BRCA1/2 (2016) (84)
Somatic KIT mutations occur predominantly in seminoma germ cell tumors and are not predictive of bilateral disease: Report of 220 tumors and review of literature (2008) (84)
Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants (2018) (83)
No evidence that protein truncating variants in BRIP1 are associated with breast cancer risk: implications for gene panel testing (2016) (83)
Genetic susceptibility to naevi--a twin study. (1991) (82)
The genetic epidemiology of early-onset epithelial ovarian cancer: a population-based study. (1999) (82)
Common alleles at 6q25.1 and 1p11.2 are associated with breast cancer risk for BRCA1 and BRCA2 mutation carriers. (2011) (82)
CAG and GGC repeat polymorphisms in the androgen receptor gene and breast cancer susceptibility in BRCA1/2 carriers and non-carriers (2001) (82)
Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma (2018) (81)
Genome-wide significant risk associations for mucinous ovarian carcinoma (2015) (81)
Common variants in mismatch repair genes and risk of invasive ovarian cancer. (2006) (81)
Genetic heterogeneity of breast-ovarian cancer revisited. Breast Cancer Linkage Consortium. (1995) (81)
Common breast cancer predisposition alleles are associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers (2008) (81)
Associations of obesity and circulating insulin and glucose with breast cancer risk: a Mendelian randomization analysis. (2018) (80)
Ovarian and Breast Cancer Risks Associated With Pathogenic Variants in RAD51C and RAD51D (2020) (80)
Evidence of linkage of the inflammatory bowel disease susceptibility locus on chromosome 16 (IBD1) to ulcerative colitis. (1998) (80)
Age at Menarche and Menopause and Breast Cancer Risk in the International BRCA1/2 Carrier Cohort Study (2007) (79)
Allelic association of the human homologue of the mouse modifier Ptprj with breast cancer. (2005) (79)
Pathology of Breast andOvarian Cancers among BRCA 1 and BRCA 2 Mutation Carriers : Results from the Consortium of Investigators of Modi fi ers of BRCA 1 / 2 ( CIMBA ) (2011) (78)
Cumulative Burden of Colorectal Cancer-Associated Genetic Variants is More Strongly Associated With Early-onset vs Late-onset Cancer. (2019) (78)
The effects of height and BMI on prostate cancer incidence and mortality: a Mendelian randomization study in 20,848 cases and 20,214 controls from the PRACTICAL consortium (2015) (78)
CYP17 promoter polymorphism and breast cancer in Australian women under age forty years. (2000) (78)
A Genome-wide Association Study of Early-Onset Breast Cancer Identifies PFKM as a Novel Breast Cancer Gene and Supports a Common Genetic Spectrum for Breast Cancer at Any Age (2014) (77)
Association Between BRCA 1 and BRCA 2 Mutations and Survival in Women With Invasive Epithelial Ovarian Cancer (2012) (77)
Common variants associated with breast cancer in genome-wide association studies are modifiers of breast cancer risk in BRCA1 and BRCA2 mutation carriers. (2010) (77)
Incorporating Truncating Variants in PALB2, CHEK2 and ATM into the BOADICEA Breast Cancer Risk Model (2016) (76)
Fine scale mapping of the breast cancer 16q12 locus. (2010) (76)
Association of single-nucleotide polymorphisms in the cell cycle genes with breast cancer in the British population. (2008) (76)
Mammographic Density, Estrogen Receptor Status and Other Breast Cancer Tumor Characteristics (2010) (76)
BRCA2 Polymorphic Stop Codon K3326X and the Risk of Breast, Prostate, and Ovarian Cancers. (2016) (76)
Breast and ovarian cancer risks in a large series of clinically ascertained families with a high proportion of BRCA1 and BRCA2 Dutch founder mutations (2013) (76)
Hand pattern indicates prostate cancer risk (2010) (76)
Incorporating tumour pathology information into breast cancer risk prediction algorithms (2010) (75)
Combined genetic and splicing analysis of BRCA1 c.[594-2A>C; 641A>G] highlights the relevance of naturally occurring in-frame transcripts for developing disease gene variant classification algorithms. (2016) (75)
Single nucleotide polymorphisms in the TP53 region and susceptibility to invasive epithelial ovarian cancer. (2009) (75)
STK15 polymorphisms and association with risk of invasive ovarian cancer. (2004) (75)
Common ERBB2 polymorphisms and risk of breast cancer in a white British population: a case–control study (2005) (74)
Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes (2019) (74)
Low dose single fraction radiotherapy in the treatment of metastatic bone pain: a pilot study. (1988) (72)
Evaluation of Fanconi Anemia genes in familial breast cancer predisposition. (2003) (72)
Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci (2019) (72)
The inherited component of cancer. (1994) (72)
Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans (2015) (71)
Evaluating Genome-Wide Association Study-Identified Breast Cancer Risk Variants in African-American Women (2013) (71)
The genetic epidemiology of BRCA1 (1994) (71)
Rare, protein-truncating variants in ATM, CHEK2 and PALB2, but not XRCC2, are associated with increased breast cancer risks (2017) (70)
Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer (2017) (70)
Contribution of germline mutations in BRCA2, P16(INK4A), P14(ARF) and P15 to uveal melanoma. (2003) (69)
Evaluating the Effectiveness of Using Standard Mammogram Form to Predict Breast Cancer Risk: Case-Control Study (2008) (69)
Five Polymorphisms and Breast Cancer Risk: Results from the Breast Cancer Association Consortium (2009) (69)
A Genome-Wide Association Study of Prognosis in Breast Cancer (2010) (69)
Apolipoprotein E4 is only a weak predictor of dementia and cognitive decline in the general population (2002) (68)
Genetic modifiers of CHEK2*1100delC associated breast cancer risk (2016) (68)
Repair in the mouse lung during low dose-rate irradiation. (1986) (68)
PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION (2018) (67)
BRCA2 Hypomorphic Missense Variants Confer Moderate Risks of Breast Cancer. (2017) (67)
Ovarian and breast cancer risks to women in families with two or more cases of ovarian cancer (2000) (67)
A somatic-mutational process recurrently duplicates germline susceptibility loci and tissue-specific super-enhancers in breast cancers (2017) (67)
Shared heritability and functional enrichment across six solid cancers (2018) (67)
Late Toxicity Is Not Increased in BRCA1/BRCA2 Mutation Carriers Undergoing Breast Radiotherapy in the United Kingdom (2006) (65)
A saturated map of common genetic variants associated with human height (2022) (65)
Constitutional mutation in exon 8 of the p53 gene in a patient with multiple primary tumours: molecular and immunohistochemical findings. (1993) (65)
Common Genetic Variation in Candidate Genes and Susceptibility to Subtypes of Breast Cancer (2009) (65)
Risk Analysis of Prostate Cancer in PRACTICAL, a Multinational Consortium, Using 25 Known Prostate Cancer Susceptibility Loci (2015) (65)
Ovarian cancer familial relative risks by tumour subtypes and by known ovarian cancer genetic susceptibility variants (2013) (65)
Tagging Single Nucleotide Polymorphisms in the BRIP1 Gene and Susceptibility to Breast and Ovarian Cancer (2007) (64)
Rat Mcs5a is a compound quantitative trait locus with orthologous human loci that associate with breast cancer risk (2007) (64)
Five endometrial cancer risk loci identified through genome-wide association analysis (2016) (64)
Presymptomatic screening for multiple endocrine neoplasia type 2A with linked DNA markers (1991) (63)
Crowdsourcing the General Public for Large Scale Molecular Pathology Studies in Cancer (2015) (63)
The CEPH consortium primary linkage map of human chromosome 10. (1990) (63)
Evidence that the 5p12 Variant rs10941679 Confers Susceptibility to Estrogen-Receptor-Positive Breast Cancer through FGF10 and MRPS30 Regulation (2016) (63)
Association between Adult Height and Risk of Colorectal, Lung, and Prostate Cancer: Results from Meta-analyses of Prospective Studies and Mendelian Randomization Analyses (2016) (62)
Common non-synonymous SNPs associated with breast cancer susceptibility: findings from the Breast Cancer Association Consortium (2014) (62)
The CASP8 -652 6N del promoter polymorphism and breast cancer risk: a multicenter study (2008) (62)
Mammographic breast density and breast cancer: evidence of a shared genetic basis. (2012) (61)
Prognostic factors in non-infiltrating carcinoma of the bladder: a preliminary report. (1982) (61)
Genome-wide association study identifies a novel variant in RAD51B associated with male breast cancer risk (2012) (61)
A Multicenter Study of Cancer Incidence in CHEK2 1100delC Mutation Carriers (2006) (61)
Common variants in mismatch repair genes and risk of colorectal cancer (2008) (60)
Comparison of 6q25 Breast Cancer Hits from Asian and European Genome Wide Association Studies in the Breast Cancer Association Consortium (BCAC) (2012) (60)
Measurement of 1,25-dihydroxyvitamin D3 receptors in breast cancer and their relationship to biochemical and clinical indices. (1984) (60)
Polygenic risk scores and breast and epithelial ovarian cancer risks for carriers of BRCA1 and BRCA2 pathogenic variants (2020) (60)
Polygenic risk scores and breast and epithelial ovarian cancer risks for carriers of BRCA1 and BRCA2 pathogenic variants (2020) (60)
Common Polymorphisms in the Prostaglandin Pathway Genes and Their Association with Breast Cancer Susceptibility and Survival (2009) (60)
Polymorphisms in CYP1A1 and smoking: no association with breast cancer risk. (2001) (60)
Common Variants at the 19p13.1 and ZNF365 Loci Are Associated with ER Subtypes of Breast Cancer and Ovarian Cancer Risk in BRCA1 and BRCA2 Mutation Carriers (2012) (60)
Generalizability of established prostate cancer risk variants in men of African ancestry (2015) (60)
Novel Associations between Common Breast Cancer Susceptibility Variants and Risk-Predicting Mammographic Density Measures. (2015) (59)
Association of the Progesterone Receptor Gene with Breast Cancer Risk: A Single-Nucleotide Polymorphism Tagging Approach (2006) (59)
Genome-Wide Association Study of Circulating Estradiol, Testosterone, and Sex Hormone-Binding Globulin in Postmenopausal Women (2012) (59)
European polygenic risk score for prediction of breast cancer shows similar performance in Asian women (2020) (59)
A recurrent truncating germline mutation in the BRIP1/FANCJ gene and susceptibility to prostate cancer (2009) (59)
Associations of common breast cancer susceptibility alleles with risk of breast cancer subtypes in BRCA1 and BRCA2 mutation carriers (2014) (58)
Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast–ovarian cancer susceptibility locus (2016) (58)
Modification of BRCA1-Associated Breast and Ovarian Cancer Risk by BRCA1-Interacting Genes. (2011) (57)
Cross Cancer Genomic Investigation of Inflammation Pathway for Five Common Cancers: Lung, Ovary, Prostate, Breast, and Colorectal Cancer. (2015) (57)
Identification of Common Variants in the SHBG Gene Affecting Sex Hormone-Binding Globulin Levels and Breast Cancer Risk in Postmenopausal Women (2008) (57)
Prognostic value of automated KI67 scoring in breast cancer: a centralised evaluation of 8088 patients from 10 study groups (2016) (57)
Evaluating the power to discriminate between highly correlated SNPs in genetic association studies (2010) (56)
Role of CHEK2*1100delC in unselected series of non‐BRCA1/2 male breast cancers (2004) (56)
The Role of KRAS rs61764370 in Invasive Epithelial Ovarian Cancer: Implications for Clinical Testing (2011) (56)
Association between a germline OCA2 polymorphism at chromosome 15q13.1 and estrogen receptor-negative breast cancer survival. (2010) (56)
Prediction of individual genetic risk to prostate cancer using a polygenic score (2015) (56)
Genetic overlap between endometriosis and endometrial cancer: evidence from cross‐disease genetic correlation and GWAS meta‐analyses (2018) (56)
Genetic variation at 9p22.2 and ovarian cancer risk for BRCA1 and BRCA2 mutation carriers. (2011) (55)
Blood lipids and prostate cancer: a Mendelian randomization analysis (2016) (55)
Assessment of polygenic architecture and risk prediction based on common variants across fourteen cancers (2019) (55)
Prognostic factors related to survival and groin recurrence following therapeutic lymph node dissection for lower limb malignant melanoma (1987) (55)
A Cross-Cancer Genetic Association Analysis of the DNA Repair and DNA Damage Signaling Pathways for Lung, Ovary, Prostate, Breast, and Colorectal Cancer (2015) (55)
A Large-Scale Analysis of Genetic Variants within Putative miRNA Binding Sites in Prostate Cancer. (2015) (54)
Genetic Risk Score Mendelian Randomization Shows that Obesity Measured as Body Mass Index, but not Waist:Hip Ratio, Is Causal for Endometrial Cancer (2016) (54)
No evidence for germline mutations in exons 5-9 of the p53 gene in 25 breast cancer families. (1992) (54)
Localisation of susceptibility genes for familial testicular germ cell tumour (2003) (53)
Functional Polymorphisms in the TERT Promoter Are Associated with Risk of Serous Epithelial Ovarian and Breast Cancers (2011) (53)
Familial predisposition to breast cancer in a British population: implications for prevention. (2000) (53)
Association of the Variants CASP8 D302H and CASP10 V410I with Breast and Ovarian Cancer Risk in BRCA1 and BRCA2 Mutation Carriers (2010) (53)
Evaluating Genetic Risk for Prostate Cancer among Japanese and Latinos (2012) (53)
Psychosocial impact of testing (by linkage) for the BRCA1 breast cancer gene: An investigation of two families in the research setting (1996) (53)
A risk prediction algorithm for ovarian cancer incorporating BRCA1, BRCA2, common alleles and other familial effects (2015) (53)
Association between invasive ovarian cancer susceptibility and 11 best candidate SNPs from breast cancer genome-wide association study. (2009) (53)
Evaluation of Association Methods for Analysing Modifiers of Disease Risk in Carriers of High‐Risk Mutations (2012) (53)
Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer (2019) (53)
Morphological and immunohistological changes in the skin in allogeneic bone marrow recipients. (1984) (52)
Association of a common AKAP9 variant with breast cancer risk: a collaborative analysis. (2008) (52)
Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation (2016) (52)
The androgen receptor CAG repeat polymorphism and modification of breast cancer risk in BRCA1 and BRCA2 mutation carriers (2004) (52)
No Association between TERT-CLPTM1L Single Nucleotide Polymorphism rs401681 and Mean Telomere Length or Cancer Risk (2010) (52)
The influence of obesity-related factors in the etiology of renal cell carcinoma—A mendelian randomization study (2019) (51)
Identification and characterization of novel associations in the CASP8/ALS2CR12 region on chromosome 2 with breast cancer risk. (2015) (51)
Testicular microlithiasis as a familial risk factor for testicular germ cell tumour (2007) (51)
CanRisk Tool—A Web Interface for the Prediction of Breast and Ovarian Cancer Risk and the Likelihood of Carrying Genetic Pathogenic Variants (2020) (51)
TGF-β Signaling Pathway and Breast Cancer Susceptibility (2011) (51)
Familial cancer syndromes (1994) (51)
CYP19A1 fine-mapping and Mendelian randomization: estradiol is causal for endometrial cancer (2015) (50)
Fine-mapping identifies two additional breast cancer susceptibility loci at 9q31.2 (2015) (50)
Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia (2018) (50)
A Genome-Wide Association Study Identifies A New Ovarian Cancer Susceptibility Locus On 9 p 22 . 2 (2010) (50)
Cis-eQTL analysis and functional validation of candidate susceptibility genes for high-grade serous ovarian cancer (2015) (50)
An autosome-wide scan for linkage disequilibrium-based association in sporadic breast cancer cases in eastern Finland: three candidate regions found. (2005) (50)
The BACE gene: genomic structure and candidate gene study in late-onset Alzheimer's disease (2001) (50)
A population study of mutations and LOH at breast cancer gene loci in tumours from sister pairs: two recurrent mutations seem to account for all BRCA1/BRCA2 linked breast cancer in Iceland. (1998) (49)
Contribution of BRCA1 and BRCA2 germ‐line mutations to the incidence of breast cancer in young women: Results from a prospective population‐based study in France (2005) (49)
Genetic Predisposition to In Situ and Invasive Lobular Carcinoma of the Breast (2014) (49)
Average age-specific cumulative risk of breast cancer according to type and site of germline mutations in BRCA1 and BRCA2 estimated from multiple-case breast cancer families attending Australian family cancer clinics (2003) (49)
Genetic variation in stromal proteins decorin and lumican with breast cancer: investigations in two case-control studies (2008) (48)
A role for XRCC2 gene polymorphisms in breast cancer risk and survival (2011) (48)
Analysis of alpha-1 antichymotrypsin, presenilin-1, angiotensin-converting enzyme, and methylenetetrahydrofolate reductase loci as candidates for dementia. (1997) (48)
Prediction of breast cancer risk based on common genetic variants in women of East Asian ancestry (2016) (47)
Fine-mapping of the HNF1B multicancer locus identifies candidate variants that mediate endometrial cancer risk (2014) (47)
Ovarian cancer susceptibility alleles and risk of ovarian cancer in BRCA1 and BRCA2 mutation carriers (2012) (47)
HPC2/ELAC2 polymorphisms and prostate cancer risk: analysis by age of onset of disease (2002) (47)
Familial relative risks for breast cancer by pathological subtype: a population-based cohort study (2010) (47)
BRCA2 arg372hispolymorphism and epithelial ovarian cancer risk (2003) (47)
Breast Cancer Risks for BRCA1/2 Carriers (2004) (46)
Genetic predisposition to ductal carcinoma in situ of the breast (2016) (46)
The International Testicular Cancer Linkage Consortium: a clinicopathologic descriptive analysis of 461 familial malignant testicular germ cell tumor kindred. (2010) (46)
Results of a genome‐wide linkage analysis in prostate cancer families ascertained through the ACTANE consortium (2003) (45)
Common variants in RB1 gene and risk of invasive ovarian cancer. (2006) (45)
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (2019) (45)
A Transcriptome-Wide Association Study Among 97,898 Women to Identify Candidate Susceptibility Genes for Epithelial Ovarian Cancer Risk. (2018) (45)
Combined effects of single nucleotide polymorphisms TP53 R72P and MDM2 SNP309, and p53 expression on survival of breast cancer patients (2009) (45)
Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use (2019) (45)
Combined quantitative measures of ER, PR, HER2, and KI67 provide more prognostic information than categorical combinations in luminal breast cancer (2019) (45)
Absence of evidence for a familial breast cancer susceptibility gene at chromosome 8p12-p22 (2000) (45)
Genome-wide association study of germline variants and breast cancer-specific mortality (2019) (44)
The genetics of familial breast cancer and their practical implications. (1994) (44)
Polyglutamine repeat length in the AIB1 gene modifies breast cancer susceptibility in BRCA1 carriers (2004) (44)
Genome-wide linkage disequilibrium mapping of late-onset Alzheimer’s disease in Finland (2001) (44)
Response to aminoglutethimide and cortisone acetate in advanced prostatic cancer. (1984) (44)
DNA mismatch repair gene MSH6 implicated in determining age at natural menopause (2013) (44)
Clinical implications of family history of prostate cancer and genetic risk single nucleotide polymorphism (SNP) profiles in an active surveillance cohort (2013) (43)
Annexin A1 expression in a pooled breast cancer series: association with tumor subtypes and prognosis (2015) (43)
Association between Common Germline Genetic Variation in 94 Candidate Genes or Regions and Risks of Invasive Epithelial Ovarian Cancer (2009) (43)
E-cadherin breast tumor expression, risk factors and survival: Pooled analysis of 5,933 cases from 12 studies in the Breast Cancer Association Consortium (2018) (43)
A quantitative analysis of the accuracy of In Vivo pH measurements with 31P NMR spectroscopy: Assessment of pH measurement methodology (1991) (42)
Gene-gene interactions in breast cancer susceptibility. (2012) (42)
Reproductive profiles and risk of breast cancer subtypes: a multi-center case-only study (2017) (42)
Human familial and sporadic breast cancer: analysis of the coding regions of the 17β-hydroxysteroid dehydrogenase 2 gene (EDH17B2) using a single-strand conformation polymorphism assay (1994) (42)
The admixture maximum likelihood test: a novel experiment‐wise test of association between disease and multiple SNPs (2006) (42)
Two ATM variants and breast cancer risk (2005) (42)
Linked markers flanking the gene for multiple endocrine neoplasia type 2A. (1989) (42)
Common variants of the BRCA1 wild-type allele modify the risk of breast cancer in BRCA1 mutation carriers. (2011) (42)
HapMap-based study of the 17q21 ERBB2 amplicon in susceptibility to breast cancer (2006) (41)
Integration of multiethnic fine-mapping and genomic annotation to prioritize candidate functional SNPs at prostate cancer susceptibility regions. (2015) (41)
Association between the GCG polymorphism of the selenium dependent GPX1 gene and the risk of young onset prostate cancer (2002) (41)
Sex differences in oncogenic mutational processes (2019) (41)
COMPLEXO: identifying the missing heritability of breast cancer via next generation collaboration (2013) (41)
Interactions between genes involved in the antioxidant defence system and breast cancer risk (2006) (40)
FastPop: a rapid principal component derived method to infer intercontinental ancestry using genetic data (2016) (40)
Characterization of the Cancer Spectrum in Men With Germline BRCA1 and BRCA2 Pathogenic Variants: Results From the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA). (2020) (40)
Adjuvant aminoglutethimide for postmenopausal patients with primary breast cancer: analysis at 8 years. (1992) (40)
Suggestive evidence for a site specific prostate cancer gene on chromosome 1p36 (2000) (40)
The UK national study of magnetic resonance imaging as a method of screening for breast cancer (MARIBS). (2002) (40)
Analysis of single-nucleotide polymorphisms in the interleukin-4 receptor gene for association with inflammatory bowel disease (2000) (40)
A genome-wide association scan on estrogen receptor-negative breast cancer (2010) (40)
Genome-wide association study of endometrial cancer in E2C2 (2013) (40)
A large-scale assessment of two-way SNP interactions in breast cancer susceptibility using 46,450 cases and 42,461 controls from the breast cancer association consortium. (2014) (40)
Models for respiratory cancer in nickel refinery workers. (1986) (40)
Inheritance of deleterious mutations at both BRCA1 and BRCA2 in an international sample of 32,295 women (2016) (39)
Genome-Wide Association Study Identifies a Possible Susceptibility Locus for Endometrial Cancer (2012) (39)
Cancer Risks Associated With BRCA1 and BRCA2 Pathogenic Variants (2022) (39)
Polymorphisms in a Putative Enhancer at the 10q21.2 Breast Cancer Risk Locus Regulate NRBF2 Expression. (2015) (39)
Familial prostate cancer: the evidence and the Cancer Research Campaign/British Prostate Group (CRC/BPG) UK Familial Prostate Cancer Study. (1997) (39)
Analysis of the DND1 gene in men with sporadic and familial testicular germ cell tumors (2008) (39)
Apoptosis, ageing and cancer susceptibility (2003) (39)
Common Single-Nucleotide Polymorphisms in DNA Double-Strand Break Repair Genes and Breast Cancer Risk (2008) (39)
Response of nitrosomethylurea-induced rat mammary tumor to endocrine therapy and comparison with clinical response. (1986) (38)
Missense Variants in ATM in 26,101 Breast Cancer Cases and 29,842 Controls (2010) (38)
Fine‐scale mapping of 8q24 locus identifies multiple independent risk variants for breast cancer (2016) (38)
Identification of four new susceptibility loci for testicular germ cell tumour (2015) (38)
Dietary fat and early-onset prostate cancer risk (2010) (38)
Body mass index and breast cancer survival: a Mendelian randomization analysis (2017) (38)
Fine-Mapping the HOXB Region Detects Common Variants Tagging a Rare Coding Allele: Evidence for Synthetic Association in Prostate Cancer (2014) (38)
Personalized Risk Assessment for Prevention and Early Detection of Breast Cancer: Integration and Implementation (PERSPECTIVE I&I) (2021) (38)
11q13 is a susceptibility locus for hormone receptor positive breast cancer (2012) (38)
An analysis of prognostic factors in early stage Hodgkin's disease. (1986) (37)
AURKA F31I Polymorphism and Breast Cancer Risk in BRCA1 and BRCA2 Mutation Carriers: A Consortium of Investigators of Modifiers of BRCA1/2 Study (2007) (37)
Quantifying the Genetic Correlation between Multiple Cancer Types (2017) (37)
Compelling evidence for a prostate cancer gene at 22q12.3 by the International Consortium for Prostate Cancer Genetics. (2007) (37)
Genetic heterogeneity and localization of a familial breast-ovarian cancer gene on chromosome 17q12-q21. (1993) (37)
Germline variation at 8q24 and prostate cancer risk in men of European ancestry (2018) (37)
Assessing Associations between the AURKA-HMMR-TPX2-TUBG1 Functional Module and Breast Cancer Risk in BRCA1/2 Mutation Carriers (2015) (37)
Evaluation of Association of HNF1B Variants with Diverse Cancers: Collaborative Analysis of Data from 19 Genome-Wide Association Studies (2010) (37)
Analysis of the contribution of HLA genes to genetic predisposition in inflammatory bowel disease. (1996) (37)
Tagging single-nucleotide polymorphisms in candidate oncogenes and susceptibility to ovarian cancer (2009) (36)
The cost-utility of magnetic resonance imaging for breast cancer in BRCA1 mutation carriers aged 30–49 (2007) (36)
Alcohol Consumption and Survival after a Breast Cancer Diagnosis: A Literature-Based Meta-analysis and Collaborative Analysis of Data for 29,239 Cases (2014) (36)
Network-Based Integration of GWAS and Gene Expression Identifies a HOX-Centric Network Associated with Serous Ovarian Cancer Risk (2015) (36)
Pubertal development and prostate cancer risk: Mendelian randomization study in a population-based cohort (2016) (36)
A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6 q 14 and 20 q 11 (2012) (36)
Common variation in Kallikrein genes KLK5, KLK6, KLK12, and KLK13 and risk of prostate cancer and tumor aggressiveness. (2013) (36)
Apo E genotypes and risk of dementia in Down syndrome. (1999) (36)
Rare coding variants and X-linked loci associated with age at menarche (2015) (36)
An intergenic risk locus containing an enhancer deletion in 2q35 modulates breast cancer risk by deregulating IGFBP5 expression. (2016) (35)
Identification of a novel percent mammographic density locus at 12q24. (2012) (35)
Risk-reducing salpingo-oophorectomy, natural menopause, and breast cancer risk: an international prospective cohort of BRCA1 and BRCA2 mutation carriers (2020) (35)
Allelotype of uterine leiomyomas. (1999) (35)
Common germline polymorphisms in COMT, CYP19A1, ESR1, PGR, SULT1E1 and STS and survival after a diagnosis of breast cancer (2009) (35)
Patient survival and tumor characteristics associated with CHEK2:p.I157T – findings from the Breast Cancer Association Consortium (2016) (35)
Investigation of gene‐environment interactions between 47 newly identified breast cancer susceptibility loci and environmental risk factors (2015) (35)
Genetic Variants Related to Longer Telomere Length are Associated with Increased Risk of Renal Cell Carcinoma. (2017) (35)
Combined Associations of a Polygenic Risk Score and Classical Risk Factors With Breast Cancer Risk (2020) (35)
Effects of common germline genetic variation in cell cycle control genes on breast cancer survival: results from a population-based cohort (2008) (35)
Genetic Variation in the Chromosome 17q23 Amplicon and Breast Cancer Risk (2009) (35)
Clinical presentation as a predictor of laparotomy findings in supradiaphragmatic stage I and II Hodgkin's disease. (1986) (34)
The genetic epidemiology of BRCA1. Breast Cancer Linkage Consortium. (1994) (34)
Prostate cancer segregation analyses using 4390 families from UK and Australian population‐based studies (2009) (34)
Cancer incidence in relatives of British Fanconi Anaemia patients (2008) (34)
BRCA1 and BRCA2 cancer risks. (2006) (34)
Adjuvant aminoglutethimide therapy for postmenopausal patients with primary breast cancer. (1987) (34)
Telomere structure and maintenance gene variants and risk of five cancer types (2016) (34)
A comprehensive examination of breast cancer risk loci in African American women. (2014) (34)
Candidate locus analysis of the TERT–CLPTM1L cancer risk region on chromosome 5p15 identifies multiple independent variants associated with endometrial cancer risk (2014) (34)
Association of Genomic Domains in BRCA1 and BRCA2 with Prostate Cancer Risk and Aggressiveness. (2019) (33)
Association of breast cancer risk with genetic variants showing differential allelic expression: Identification of a novel breast cancer susceptibility locus at 4q21 (2016) (33)
Confirmation of 5p12 As a Susceptibility Locus for Progesterone-Receptor–Positive, Lower Grade Breast Cancer (2011) (33)
Germline determinants of the somatic mutation landscape in 2,642 cancer genomes (2017) (33)
Inherited mutations in BRCA1 and BRCA2 in an unselected multiethnic cohort of Asian patients with breast cancer and healthy controls from Malaysia (2017) (33)
Identification of New Genetic Susceptibility Loci for Breast Cancer Through Consideration of Gene‐Environment Interactions (2014) (33)
Breast cancer screening: time to target women at risk (2013) (33)
Magnetic resonance imaging screening in women at genetic risk of breast cancer: imaging and analysis protocol for the UK multicentre study. UK MRI Breast Screening Study Advisory Group. (2000) (33)
Diagnostic radiation procedures and risk of prostate cancer (2008) (33)
Genome-wide association study of classical Hodgkin lymphoma identifies key regulators of disease susceptibility (2017) (32)
Evaluation of a prospective scoring system designed for a multicenter breast MR imaging screening study. (2006) (32)
The Effects of Common Genetic Variants in Oncogenes on Ovarian Cancer Survival (2008) (32)
Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1 (2015) (32)
Respiratory cancer mortality in welsh nickel refiners : which nickel compounds are responsible? (1992) (32)
Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus (2016) (32)
Common germline polymorphisms associated with breast cancer-specific survival (2015) (31)
Evidence for SMAD3 as a modifier of breast cancer risk in BRCA2 mutation carriers (2010) (31)
A Mendelian randomization analysis of circulating lipid traits and breast cancer risk. (2019) (31)
Acute Chemotherapy–Related Toxicity Is Not Increased in BRCA1 and BRCA2 Mutation Carriers Treated for Breast Cancer in the United Kingdom (2006) (31)
Bulky mediastinal Hodgkin's disease management and prognosis (1984) (31)
Optimal strategies for mapping complex diseases in the presence of multiple loci. (1997) (31)
Genetic variation at CYP3A is associated with age at menarche and breast cancer risk: a case-control study (2014) (31)
Germline BRCA 1 mutations increase prostate cancer risk (2015) (31)
Association of PHB 1630 C>T and MTHFR 677 C>T polymorphisms with breast and ovarian cancer risk in BRCA1/2 mutation carriers: results from a multicenter study (2012) (31)
Multi-stage genome-wide association study identifies new susceptibility locus for testicular germ cell tumour on chromosome 3q25. (2015) (31)
Prevalence of BRCA1 and BRCA2 pathogenic variants in a large, unselected breast cancer cohort (2018) (31)
Genome-Wide Association Study of Prostate Cancer–Specific Survival (2015) (30)
Breast cancer—not just whether but when? (2000) (30)
Genetic Variation in Prostate-Specific Antigen–Detected Prostate Cancer and the Effect of Control Selection on Genetic Association Studies (2014) (30)
Common Polymorphisms in ERCC2 (Xeroderma pigmentosum D) are not Associated with Breast Cancer Risk (2005) (30)
Effects of Common Germ-Line Genetic Variation in Cell Cycle Genes on Ovarian Cancer Survival (2008) (30)
Sexual activity and prostate cancer risk in men diagnosed at a younger age (2009) (29)
Area and Volumetric Density Estimation in Processed Full-Field Digital Mammograms for Risk Assessment of Breast Cancer (2014) (29)
Candidate Genetic Modifiers for Breast and Ovarian Cancer Risk in BRCA1 and BRCA2 Mutation Carriers (2014) (29)
Joint association of mammographic density adjusted for age and body mass index and polygenic risk score with breast cancer risk (2019) (29)
Polyunsaturated fatty acids and prostate cancer risk: a Mendelian randomisation analysis from the PRACTICAL consortium (2016) (28)
Evaluation of a candidate breast cancer associated SNP in ERCC4 as a risk modifier in BRCA1 and BRCA2 mutation carriers. Results from the Consortium of Investigators of Modifiers of BRCA1/BRCA2 (CIMBA) (2009) (28)
No germline mutations in the dimerization domain of MXI1 in prostate cancer clusters. The CRC/BPG UK Familial Prostate Cancer Study Collaborators. Cancer Research Campaign/British Prostate Group. (1997) (28)
Rationale for a national multi-centre study of magnetic resonance imaging screening in women at genetic risk of breast cancer. (2000) (28)
Genetic variant predictors of gene expression provide new insight into risk of colorectal cancer (2019) (28)
Polygenic inherited predisposition to breast cancer. (2005) (28)
The AIB1 Polyglutamine Repeat Does Not Modify Breast Cancer Risk in BRCA1 and BRCA2 Mutation Carriers (2006) (28)
No Association between FTO or HHEX and Endometrial Cancer Risk (2010) (28)
Linkage analysis of 56 multiplex families excludes the Cowden disease genePTEN as a major contributor to familial breast cancer (1999) (27)
A network analysis to identify mediators of germline-driven differences in breast cancer prognosis (2020) (27)
Evaluating clinician acceptability of the prototype CanRisk tool for predicting risk of breast and ovarian cancer: A multi-methods study (2020) (27)
Association analysis of 9,560 prostate cancer cases from the International Consortium of Prostate Cancer Genetics confirms the role of reported prostate cancer associated SNPs for familial disease (2014) (27)
Evaluating genetic variants associated with breast cancer risk in high and moderate-penetrance genes in Asians (2017) (27)
Pathology of Tumors Associated With Pathogenic Germline Variants in 9 Breast Cancer Susceptibility Genes (2022) (27)
Genetically predicted levels of DNA methylation biomarkers and breast cancer risk: data from 228,951 women of European descent. (2019) (27)
Fine scale mapping of the 17q22 breast cancer locus using dense SNPs, genotyped within the Collaborative Oncological Gene-Environment Study (COGs) (2016) (27)
Breast Cancer Polygenic Risk Score and Contralateral Breast Cancer Risk. (2020) (27)
Variants in CHEK 2 Other than 1100 delC Do Not Make a Major Contribution to Breast Cancer Susceptibility (2003) (27)
Apparent human BRCA1 knockout caused by mispriming during polymerase chain reaction: Implications for genetic testing (2001) (27)
Supportive care management of brain metastases: what is known and what we need to know. Conference proceedings of the National Cancer Institute of Canada (NCIC) Workshop on Symptom Control in Radiation Oncology. (2003) (27)
Association between leptin receptor gene polymorphisms and early‐onset prostate cancer (2003) (27)
Oral Contraceptive Use and Breast Cancer Risk: Retrospective and Prospective Analyses From a BRCA1 and BRCA2 Mutation Carrier Cohort Study (2018) (26)
Mutation analysis of the MSMB gene in familial prostate cancer (2009) (26)
Assessing the role of insulin‐like growth factors and binding proteins in prostate cancer using Mendelian randomization: Genetic variants as instruments for circulating levels (2016) (26)
Second malignancies and Hodgkin's disease--the Royal Marsden Hospital experience. (1988) (26)
Common Genetic Variation in Circadian Rhythm Genes and Risk of Epithelial Ovarian Cancer (EOC) (2015) (26)
Endometrial cancer and genetic variation in PTEN, PIK3CA, AKT1, MLH1, and MSH2 within a population-based case-control study. (2011) (26)
Genome‐wide linkage analysis of 1,233 prostate cancer pedigrees from the International Consortium for prostate cancer Genetics using novel sumLINK and sumLOD analyses (2010) (26)
A Genetic Risk Score to Personalize Prostate Cancer Screening, Applied to Population Data (2019) (26)
Polymorphisms in Inflammation Pathway Genes and Endometrial Cancer Risk (2012) (26)
Polygenic risk score is associated with increased disease risk in 52 Finnish breast cancer families (2016) (25)
Macrophage Scavenger Receptor 1 999C>T (R293X) Mutation and Risk of Prostate Cancer (2005) (25)
Variation in BRCA 1 Cancer Risks by Mutation Position 1 (2002) (25)
Educational attainment and mean leukocyte telomere length in women in the European Prospective Investigation into Cancer (EPIC)-Norfolk population study (2012) (25)
Fine-Scale Mapping of the 4q24 Locus Identifies Two Independent Loci Associated with Breast Cancer Risk (2015) (25)
Identification of novel breast cancer susceptibility loci in meta-analyses conducted among Asian and European descendants (2020) (25)
Mendelian randomization analyses suggest a role for cholesterol in the development of endometrial cancer (2020) (25)
The TP53 Arg72Pro and MDM2 309G>T polymorphisms are not associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers (2009) (25)
An original phylogenetic approach identified mitochondrial haplogroup T1a1 as inversely associated with breast cancer risk in BRCA2 mutation carriers (2015) (25)
Alcohol consumption and prostate cancer incidence and progression: A Mendelian randomisation study (2016) (25)
An integrative multi-omics analysis to identify candidate DNA methylation biomarkers related to prostate cancer risk (2020) (25)
High risk genes predisposing to prostate cancer development—do they exist? (2000) (24)
A Common Variant at the 14q32 Endometrial Cancer Risk Locus Activates AKT1 through YY1 Binding. (2016) (24)
The management of advanced testicular teratoma. (1988) (24)
Bromodomain protein 4 discriminates tissue-specific super-enhancers containing disease-specific susceptibility loci in prostate and breast cancer (2017) (24)
The genetic interplay between body mass index, breast size and breast cancer risk: a Mendelian randomization analysis (2019) (24)
Presurgical determination of estrogen receptor status using immunocytochemically stained fine needle aspirate smears in patients with breast cancer. (1987) (24)
No evidence for an association between Saitohin Q7R polymorphism and Alzheimer's disease (2002) (24)
The Heritability of Mammographic Breast Density and Circulating Sex-Hormone Levels: Two Independent Breast Cancer Risk Factors (2012) (24)
Common polymorphisms in checkpoint kinase 2 are not associated with breast cancer risk. (2003) (24)
Genome-wide association study of subtype-specific epithelial ovarian cancer risk alleles using pooled DNA (2013) (24)
Regional localization of polymorphic markers on chromosome 10 by physical and genetic mapping (1990) (24)
9q31.2-rs865686 as a Susceptibility Locus for Estrogen Receptor-Positive Breast Cancer: Evidence from the Breast Cancer Association Consortium (2012) (24)
A physical analysis of the Y chromosome shows no additional deletions, other than Gr/Gr, associated with testicular germ cell tumour (2007) (24)
Absence of linkage to the ataxia telangiectasia locus in familial breast cancer (1993) (24)
Effects of BRCA2 cis-regulation in normal breast and cancer risk amongst BRCA2 mutation carriers (2012) (23)
Validation of prostate cancer risk-related loci identified from genome-wide association studies using family-based association analysis: evidence from the International Consortium for Prostate Cancer Genetics (ICPCG) (2012) (23)
Performance of automated scoring of ER, PR, HER2, CK5/6 and EGFR in breast cancer tissue microarrays in the Breast Cancer Association Consortium (2014) (23)
Association of ESR 1 gene tagging SNPs with breast cancer risk (2009) (23)
Mismatch repair gene polymorphisms and survival in invasive ovarian cancer patients. (2008) (23)
Comprehensive genetic assessment of the ESR1 locus identifies a risk region for endometrial cancer. (2015) (23)
Identification of new genetic risk factors for prostate cancer. (2009) (23)
Mendelian randomization analysis of C-reactive protein on colorectal cancer risk. (2018) (23)
Genetic Models for the Familial Aggregation of Mammographic Breast Density (2009) (23)
Familial cancer risks to offspring from mothers with 2 primary breast cancers: Leads to cancer syndromes (2000) (23)
High‐throughput automated scoring of Ki67 in breast cancer tissue microarrays from the Breast Cancer Association Consortium (2016) (23)
Genetic modifiers of menopausal hormone replacement therapy and breast cancer risk: a genome-wide interaction study. (2013) (23)
The Influence of Number and Timing of Pregnancies on Breast Cancer Risk for Women With BRCA1 or BRCA2 Mutations (2018) (23)
Genetic susceptibility to radiation-induced breast cancer after Hodgkin lymphoma. (2019) (23)
BRCA1 and BRCA2 pathogenic sequence variants in women of African origin or ancestry (2019) (22)
Genetic Variation in TYMS in the One-Carbon Transfer Pathway Is Associated with Ovarian Carcinoma Types in the Ovarian Cancer Association Consortium (2010) (22)
Evaluating Polygenic Risk Scores for Breast Cancer in Women of African Ancestry. (2021) (22)
Decreased breast cancer risk in systemic lupus erythematosus: the search for a genetic basis continues (2012) (22)
A Nonsynonymous Polymorphism in IRS1 Modifies Risk of Developing Breast and Ovarian Cancers in BRCA1 and Ovarian Cancer in BRCA2 Mutation Carriers (2012) (22)
Prediction and clinical utility of a contralateral breast cancer risk model (2019) (22)
Family history of breast cancer (2005) (22)
Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples (2020) (22)
FGF receptor genes and breast cancer susceptibility: results from the Breast Cancer Association Consortium (2014) (22)
Partnering in Oncogenetic Research – The INHERIT BRCAs Experience: Opportunities and Challenges (2005) (22)
Chromatin interactome mapping at 139 independent breast cancer risk signals (2019) (22)
Identification of Women at High Risk of Breast Cancer Who Need Supplemental Screening. (2020) (22)
Increased activity of serum amine oxidases in granuloma annulare, necrobiosis lipoidica and diabetes (1987) (21)
The Reliable Identification of Disease-Gene Associations (2005) (21)
Exome array analysis identifies ETFB as a novel susceptibility gene for anthracycline-induced cardiotoxicity in cancer patients (2017) (21)
A test of performance of breast MRI interpretation in a multicentre screening study. (2006) (21)
Polymorphism in the IL18 Gene and Epithelial Ovarian Cancer in Non-Hispanic White Women (2008) (21)
Breast cancer susceptibility risk associations and heterogeneity by E-cadherin tumor tissue expression (2013) (21)
Epithelial‐Mesenchymal Transition (EMT) Gene Variants and Epithelial Ovarian Cancer (EOC) Risk (2015) (21)
Genetic architectures of proximal and distal colorectal cancer are partly distinct (2020) (21)
Exploring the link between MORF4L1 and risk of breast cancer (2011) (21)
GWAS meta-analysis of 16 852 women identifies new susceptibility locus for endometrial cancer. (2016) (21)
Physical activity and mammographic breast density in the EPIC-Norfolk cohort study. (2007) (21)
Assessment of variation in immunosuppressive pathway genes reveals TGFBR2 to be associated with prognosis of estrogen receptor-negative breast cancer after chemotherapy (2015) (20)
Personalizing Breast Cancer Screening Based on Polygenic Risk and Family History (2020) (20)
Genetic association of anLBP-1c/CP2/LSFgene polymorphism with late onset Alzheimer's disease (2001) (20)
Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (2017) (20)
Association of breast cancer risk in BRCA1 and BRCA2 mutation carriers with genetic variants showing differential allelic expression: identification of a modifier of breast cancer risk at locus 11q22.3 (2016) (20)
Functional complementation studies identify candidate genes and common genetic variants associated with ovarian cancer survival. (2009) (20)
Computerized tomographic simulation compared with clinical mark-up in palliative radiotherapy: a prospective study. (2006) (20)
Cancer mortality in the first degree relatives of young breast cancer patients. (1992) (20)
Hyaluronan-Mediated Motility Receptor Gene Single Nucleotide Polymorphisms and Risk of Breast Cancer (2008) (20)
Differential Burden of Rare and Common Variants on Tumor Characteristics, Survival, and Mode of Detection in Breast Cancer. (2018) (20)
Association of genetic susceptibility variants for type 2 diabetes with breast cancer risk in women of European ancestry (2016) (20)
A comprehensive evaluation of interaction between genetic variants and use of menopausal hormone therapy on mammographic density (2015) (20)
Apo E and Apo CI Loci Are Associated with Dementia in Younger But Not Older Late-Onset Cases (1998) (20)
Correction: BOADICEA: a comprehensive breast cancer risk prediction model incorporating genetic and nongenetic risk factors (2019) (20)
Use of deep whole-genome sequencing data to identify structure risk variants in breast cancer susceptibility genes (2018) (20)
The FANCM:p.Arg658* truncating variant is associated with risk of triple-negative breast cancer (2019) (20)
Etiology of hormone receptor positive breast cancer differs by levels of histologic grade and proliferation (2018) (19)
2q36.3 is associated with prognosis for oestrogen receptor-negative breast cancer patients treated with chemotherapy (2014) (19)
Prospective evaluation of a breast-cancer risk model integrating classical risk factors and polygenic risk in 15 cohorts from six countries. (2021) (19)
Haplotype structure in Ashkenazi Jewish BRCA1 and BRCA2 mutation carriers (2011) (19)
Breast cancer risk factors and their effects on survival: a Mendelian randomisation study (2020) (19)
Assessment of interactions between 205 breast cancer susceptibility loci and 13 established risk factors in relation to breast cancer risk, in the Breast Cancer Association Consortium (2019) (19)
Genetic association of an LBP-1c / CP2 / LSF gene polymorphism with late onset Alzheimer’s disease (2001) (19)
Common germline variation in mismatch repair genes and survival after a diagnosis of colorectal cancer (2009) (19)
Polymorphisms of an Innate Immune Gene, Toll-Like Receptor 4, and Aggressive Prostate Cancer Risk: A Systematic Review and Meta-Analysis (2014) (19)
Is Schizophrenia a Risk Factor for Breast Cancer?-Evidence From Genetic Data. (2018) (19)
Localisation of the breast‐ovarian cancer susceptibility gene (BRCAI) on 17q12–21 to an interval of ⩽IcM (1994) (19)
Gene–environment interactions involving functional variants: Results from the Breast Cancer Association Consortium (2017) (19)
Cancer treatment trials--past failures, current progress and future prospects. (1989) (19)
Sex specific associations in genome wide association analysis of renal cell carcinoma (2019) (19)
Oral contraceptive use and ovarian cancer risk for BRCA1/2 mutation carriers: an international cohort study (2021) (18)
Genomic analysis of male puberty timing highlights shared genetic basis with hair colour and lifespan (2020) (18)
The BRCA2 c.68‐7T > A variant is not pathogenic: A model for clinical calibration of spliceogenicity (2018) (18)
No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer. (2016) (18)
Large-scale Analysis Demonstrates Familial Testicular Cancer to have Polygenic Aetiology. (2018) (18)
Younger age-at-diagnosis for familial malignant testicular germ cell tumor (2009) (18)
High Prevalence of the 999 del 5 Mutation in Icelandic Breast and Ovarian Cancer Patients 1 (2006) (18)
A genome-wide association study to identify genetic susceptibility loci that modify ductal and lobular postmenopausal breast cancer risk associated with menopausal hormone therapy use: a two-stage design with replication (2013) (18)
An investigation of ACE as a risk factor for dementia and cognitive decline in the general population (2002) (18)
A genetic study and meta-analysis of the genetic predisposition of prostate cancer in a Chinese population (2016) (18)
Non-coding RNAs underlie genetic predisposition to breast cancer (2020) (17)
Alcohol Consumption, Cigarette Smoking, and Risk of Breast Cancer for BRCA1 and BRCA2 Mutation Carriers: Results from The BRCA1 and BRCA2 Cohort Consortium (2019) (17)
Identification of 31 loci for mammographic density phenotypes and their associations with breast cancer risk (2020) (17)
Risks of breast or ovarian cancer in BRCA1 or BRCA2 predictive test negatives: findings from the EMBRACE study (2018) (17)
Rare germline copy number deletions of likely functional importance are implicated in endometrial cancer predisposition (2015) (17)
Correction: Common Genetic Variants and Modification of Penetrance of BRCA2-Associated Breast Cancer (2010) (17)
Height and Body Mass Index as Modifiers of Breast Cancer Risk in BRCA1/2 Mutation Carriers: A Mendelian Randomization Study. (2018) (17)
Investigating the possible causal role of coffee consumption with prostate cancer risk and progression using Mendelian randomization analysis (2016) (17)
Exome array analysis identifies GPR35 as a novel susceptibility gene for anthracycline-induced cardiotoxicity in childhood cancer (2017) (17)
Immunological and histochemical analysis of regional variations of epidermal Langerhans cells in normal human skin (1984) (17)
Identification of shared and unique susceptibility pathways among cancers of the lung, breast, and prostate from genome-wide association studies and tissue-specific protein interactions. (2015) (16)
Genome-wide association study of susceptibility loci for breast cancer in Sardinian population (2015) (16)
Corrigendum: Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue (2015) (16)
Incorporating Functional Genomic Information in Genetic Association Studies Using an Empirical Bayes Approach (2016) (16)
BRCA1/BRCA2 mutation status and analysis of cancer family history in participants of the Royal Marsden Hospital tamoxifen chemoprevention trial. (2007) (16)
Common variants at 12p11, 12q24, 9p21, 9q31.2 and in ZNF365 are associated with breast cancer risk for BRCA1 and/or BRCA2mutation carriers (2012) (16)
Eligibility for Magnetic Resonance Imaging Screening in the United Kingdom: Effect of Strict Selection Criteria and Anonymous DNA Testing on Breast Cancer Incidence in the MARIBS Study (2009) (16)
Transcriptome-wide association study of breast cancer risk by estrogen-receptor status (2020) (16)
Common Genetic Variation at BARD1 Is Not Associated with Breast Cancer Risk in BRCA1 or BRCA2 Mutation Carriers (2011) (16)
Association study of prostate cancer susceptibility variants with risks of invasive ovarian, breast, and colorectal cancer. (2008) (16)
Genome-wide association study implicates immune dysfunction in the development of Hodgkin lymphoma. (2018) (16)
Genetic modifiers of CHEK 2 * 1100 delC-associated breast cancer risk (2017) (15)
Reply to “Variation in KLK genes, prostate-specific antigen and risk of prostate cancer” (2008) (15)
The SNP rs6500843 in 16p13.3 is associated with survival specifically among chemotherapy-treated breast cancer patients (2015) (15)
Common colorectal cancer risk alleles contribute to the multiple colorectal adenoma phenotype, but do not influence colonic polyposis in FAP (2014) (15)
Radiotherapy results in laparotomy-staged Hodgkin's disease. (1988) (15)
The management of early‐stage aggressive non‐Hodgkin's lymphoma (1988) (15)
SNP-SNP interaction analysis of NF-κB signaling pathway on breast cancer survival (2015) (15)
Mendelian randomisation study of height and body mass index as modifiers of ovarian cancer risk in 22,588 BRCA1 and BRCA2 mutation carriers (2019) (15)
Association between Prostinogen (KLK15) Genetic Variants and Prostate Cancer Risk and Aggressiveness in Australia and a Meta-Analysis of GWAS Data (2011) (15)
CHEK2, MGMT, SULT1E1 and SULT1A1 Polymorphisms and Endometrial Cancer Risk (2011) (15)
The admixture maximum likelihood test to test for association between rare variants and disease phenotypes (2013) (15)
Contribution of Germline Mutations in BRCA 2 , P 16 INK 4 A , P 14 ARF and P 15 to Uveal Melanoma (2003) (15)
A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers (2021) (15)
Lack of mutagenic activity of bile acids in bacterial fluctuation tests. (1987) (15)
Alzheimer disease is not associated with polymorphisms in the angiotensinogen and renin genes. (2001) (14)
Linkage analysis of chromosome 17 markers in British and South African families with neurofibromatosis type I. (1989) (14)
Prevalence and penetrance of mutations in BRCA1 and BRCA2 in a population based series of breast cancer cases (2000) (14)
Genome-wide association study of endometrial cancer in E 2 C 2 (2014) (14)
Breast Cancer Risk Factors and Survival by Tumor Subtype: Pooled Analyses from the Breast Cancer Association Consortium (2021) (14)
Comprehensive epithelial tubo-ovarian cancer risk prediction model incorporating genetic and epidemiological risk factors (2020) (14)
SNP interaction pattern identifier (SIPI): an intensive search for SNP‐SNP interaction patterns (2016) (14)
COVID-19 Vaccine Effectiveness by Product and Timing in New York State (2021) (14)
A 45-year follow-up of kindred 107 and the search for BRCA2. (1995) (14)
Reducing GWAS Complexity (2016) (14)
Breast Cancer Risk and 6q22.33: Combined Results from Breast Cancer Association Consortium and Consortium of Investigators on Modifiers of BRCA1/2 (2012) (14)
Fine-Mapping of the 1p11.2 Breast Cancer Susceptibility Locus (2016) (14)
SNPs in the kallikrein gene region associated with prostate cancer risk: true cause or association by design? (2008) (14)
Inherited variants in the inner centromere protein (INCENP) gene of the chromosomal passenger complex contribute to the susceptibility of ER-negative breast cancer. (2015) (14)
Gene and pathway level analyses of germline DNA-repair gene variants and prostate cancer susceptibility using the iCOGS-genotyping array (2016) (14)
Chromosomes 4 and 8 implicated in a genome wide SNP linkage scan of 762 prostate cancer families collected by the ICPCG (2012) (14)
Common Genetic Variants and Modification of Penetrance of BRCA 2-Associated Breast Cancer (2010) (14)
Survival in Familial, BRCA1 -associated, and BRCA2- associated Epithelial Ovarian Cancer 1 (1999) (14)
Genetic variation in mitotic regulatory pathway genes is associated with breast tumor grade. (2014) (14)
Common variation in EMSY and risk of breast and ovarian cancer: a case-control study using HapMap tagging SNPs (2005) (14)
Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17 q 21 . 31 (2013) (14)
Lymphocyte Telomere Length Is Long in BRCA1 and BRCA2 Mutation Carriers Regardless of Cancer-Affected Status (2014) (14)
Evaluation of the XRCC1 gene as a phenotypic modifier in BRCA1/2 mutation carriers. Results from the consortium of investigators of modifiers of BRCA1/BRCA2 (2011) (13)
No evidence that CDKN1B (p27) polymorphisms modify breast cancer risk in BRCA1 and BRCA2 mutation carriers (2009) (13)
Common genetic variants associated with disease from genome-wide association studies are mutually exclusive in prostate cancer and rheumatoid arthritis (2012) (13)
No association of TGFB1 L10P genotypes and breast cancer risk in BRCA1 and BRCA2 mutation carriers: a multi-center cohort study (2009) (13)
SCREENING FOR PROSTATE CANCER: THE WAY AHEAD (2010) (13)
No evidence that GATA3 rs570613 SNP modifies breast cancer risk (2009) (13)
Risks of Breast, Ovarian, and Contralateral Breast Cancer for $\textit{BRCA1}$ and $\textit{BRCA2}$ Mutation Carriers (2017) (13)
The effect of sample size on polygenic hazard models for prostate cancer (2019) (12)
A response to “Personalised medicine and population health: breast and ovarian cancer” (2019) (12)
Familial risks of cancer. (1999) (12)
Is the genetics of moliness simply the genetics of sun exposure? A path analysis of nevus counts and risk factors in British twins. (1992) (12)
Comparison of conservative surgery and radiotherapy with mastectomy in the treatment of early breast cancer. (1990) (12)
Re-evaluating genetic variants identified in candidate gene studies of breast cancer risk using data from nearly 280,000 women of Asian and European ancestry (2019) (12)
Prediction of contralateral breast cancer: external validation of risk calculators in 20 international cohorts (2020) (12)
Role of MC1R variants in uveal melanoma (2003) (12)
Evaluation of an algorithm of tagging SNPs selection by linkage disequilibrium. (2006) (12)
No evidence of germline PTEN mutations in familial prostate cancer (2000) (12)
Prostate cancer meta-analysis from more than 143,000 men identifies 57 novel prostate cancer susceptibility loci (2016) (11)
Polygenic risk modeling for prediction of epithelial ovarian cancer risk (2022) (11)
HOXB13 is a susceptibility gene for prostate cancer: results from the International Consortium for Prostate Cancer Genetics (ICPCG) (2012) (11)
Exclusion of linkage of loci on chromosome 19 with multiple endocrine neoplasia, type 2. (1987) (11)
Single-nucleotide polymorphisms in the RB1 gene and association with breast cancer in the British population (2006) (11)
National Cancer Institute Prostate Cancer Genetics Workshop. (2011) (11)
The effects of height and BMI on prostate cancer incidence and mortality: a Mendelian randomization study in 20,848 cases and 20,214 controls from the PRACTICAL consortium (2015) (11)
Pooled analysis indicates that the GSTT1 deletion, GSTM1 deletion, and GSTP1 Ile105Val polymorphisms do not modify breast cancer risk in BRCA1 and BRCA2 mutation carriers (2010) (11)
Author Correction: Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci (2019) (11)
pedigreejs: a web-based graphical pedigree editor (2017) (11)
Single Nucleotide Polymorphisms in the TP 53 Region and Susceptibility to Invasive Epithelial Ovarian Cancer (2009) (11)
4-Hydroxyandrostenedione in the prophylaxis of N-methyl-N-nitrosourea induced mammary tumourigenesis. (1991) (11)
Linkage analysis of British and Indian families with Von Recklinghausen neurofibromatosis. (1987) (11)
Validation of loci at 2q14.2 and 15q21.3 as risk factors for testicular cancer (2017) (10)
TP53-based interaction analysis identifies cis-eQTL variants for TP53BP2, FBXO28, and FAM53A that associate with survival and treatment outcome in breast cancer (2017) (10)
Telomere Length Shows No Association with BRCA1 and BRCA2 Mutation Status (2014) (10)
Germline mutations in fumarate hydratase (FH) do not predispose to prostate cancer (2003) (10)
Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche DTU Orbit (05/11/2017) (2014) (10)
The predictive ability of the 313 variant–based polygenic risk score for contralateral breast cancer risk prediction in women of European ancestry with a heterozygous BRCA1 or BRCA2 pathogenic variant (2021) (10)
Preface to the breast cancer linkage consortium papers (1993) (10)
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (2018) (10)
AURKA F 31 I Polymorphism and Breast Cancer Risk in BRCA 1 and BRCA 2 Mutation Carriers : A Consortium of Investigators of Modifiers of BRCA 1 / 2 Study (2007) (10)
The KL-VS sequence variant of Klotho and cancer risk in BRCA1 and BRCA2 mutation carriers (2012) (10)
Genetic variation in the immunosuppression pathway genes and breast cancer susceptibility: a pooled analysis of 42,510 cases and 40,577 controls from the Breast Cancer Association Consortium (2015) (10)
Prospective Evaluation of a Breast Cancer Risk Model Integrating Classical Risk Factors and Polygenic Risk in 15 Cohorts from Six Countries (2019) (10)
Cross-ancestry GWAS meta-analysis identifies six breast cancer loci in African and European ancestry women (2021) (10)
A polymorphism in the base excision repair gene PARP2 is associated with differential prognosis by chemotherapy among postmenopausal breast cancer patients (2015) (10)
Novel Bayes Factors That Capture Expert Uncertainty in Prior Density Specification in Genetic Association Studies (2015) (10)
Prognosis following chemotherapy for metastatic malignant teratoma. (1987) (10)
Serum Estradiol and 20 Site-Specific Cancers in Women: Mendelian Randomization Study (2021) (10)
Fine-Scale Mapping at 9p22.2 Identifies Candidate Causal Variants That Modify Ovarian Cancer Risk in BRCA1 and BRCA2 Mutation Carriers (2016) (9)
Fine-mapping of 150 breast cancer risk regions identifies 178 high confidence target genes (2019) (9)
PHIP - a novel candidate breast cancer susceptibility locus on 6q14.1 (2017) (9)
Variants in genes encoding small GTPases and association with epithelial ovarian cancer susceptibility (2018) (9)
Use of the BOADICEA Web Application in clinical practice: appraisals by clinicians from various countries (2017) (9)
Common Susceptibility Loci for Male Breast Cancer (2020) (9)
Evaluation of associations between genetically predicted circulating protein biomarkers and breast cancer risk (2020) (9)
Protocol for a national multi-centre study of magnetic resonance imaging screening in women at genetic risk of breast cancer. (2000) (9)
Linkage analysis and genetic models for IDDM (1989) (9)
Comment on: Polymorphisms associated with circulating sex hormone levels in postmenopausal women. Authors' reply (2005) (9)
Gene and pathway level analyses of germline DNA-repair gene variants and prostate cancer susceptibility using the iCOGS-genotyping array (2016) (9)
Genome-Wide Association Study for Ovarian Cancer Susceptibility Using Pooled DNA (2012) (9)
First international workshop of the ATM and cancer risk group (4-5 December 2019) (2021) (9)
Breast and Prostate Cancer Risks for Male BRCA1 and BRCA2 Pathogenic Variant Carriers Using Polygenic Risk Scores (2021) (9)
Genomic risk prediction of coronary artery disease in women with breast cancer: a prospective cohort study (2021) (9)
Splicing predictions, minigene analyses, and ACMG‐AMP clinical classification of 42 germline PALB2 splice‐site variants (2021) (8)
Risk factors and clinical data related to oestrogen receptor status in women presenting with breast cancer (1985) (8)
Generation Scotland (2015) (8)
No evidence for population substructure within the EPIC-Norfolk cohort (2005) (8)
A multilayered post-GWAS assessment on genetic susceptibility to pancreatic cancer (2020) (8)
Corrigendum: The genomic landscape of juvenile myelomonocytic leukemia (2015) (8)
Risk Models for Familial Breast and Ovarian Cancer (1999) (8)
Exploring the link between MORF4L1 and risk of breast cancer (2011) (8)
Clinical software development for the Web: lessons learned from the BOADICEA project (2012) (8)
Clinical Guidelines and Evidence Report for The classification and care of women at risk of familial breast cancer in primary, secondary and tertiary care. (2004) (8)
Elevated expression of Ki-67 identifies aggressive prostate cancers but does not distinguish BRCA1 or BRCA2 mutation carriers. (2009) (8)
The study of nevi in British twins: study design and description of the data set. (1992) (8)
Enhancing the BOADICEA cancer risk prediction model to incorporate new data on RAD51C, RAD51D, BARD1 updates to tumour pathology and cancer incidence (2022) (8)
Comprehensive Functional Characterization and Clinical Interpretation of 20 Splice-Site Variants of the RAD51C Gene (2020) (8)
Prostate cancer meta-analysis from more than 145,000 men to identify 65 novel prostate cancer susceptibility loci. (2017) (8)
Prostate cancer risk regions at 8q24 and 17q24 are differentially associated with somatic TMPRSS2:ERG fusion status (2016) (8)
Screening for the BRCA1‐ins6kbEx13 mutation: potential for misdiagnosis (2007) (8)
HLA and inflammatory bowel disease (1996) (7)
The Genetics of Testicular Germ Cell Tumours (2002) (7)
Analysis of Xq27-28 linkage in the international consortium for prostate cancer genetics (ICPCG) families (2012) (7)
Evaluating the role of alcohol consumption in breast and ovarian cancer susceptibility using population‐based cohort studies and two‐sample Mendelian randomization analyses (2020) (7)
Re: "Presenting statistical uncertainty in trends and dose-response relations". (2000) (7)
Detecting rare copy number variants (CNVs) from Illumina genotyping arrays with the CamCNV pipeline: segmentation of z-scores improves detection and reliability (2020) (7)
Frequency of familial melanoma and MLM2 gene (1995) (7)
The functional ALDH2 polymorphism is associated with breast cancer risk: A pooled analysis from the Breast Cancer Association Consortium (2019) (7)
Clinicians’ use of breast cancer risk assessment tools according to their perceived importance of breast cancer risk factors: an international survey (2018) (7)
Investigation of interleukin-10 and vascular endothelial growth factor single nucleotide polymorphisms in predisposition to breast cancer (2004) (7)
FastPop: a rapid principal component derived method to infer intercontinental ancestry using genetic data (2016) (7)
Heterogeneity of luminal breast cancer characterised by immunohistochemical expression of basal markers (2015) (7)
Targeted Resequencing of the Coding Sequence of 38 Genes Near Breast Cancer GWAS Loci in a Large Case–Control Study (2019) (7)
TGF-b Signaling Pathway and Breast Cancer Susceptibility (2011) (7)
Modification of BRCA 1-Associated Breast and Ovarian Cancer Risk by BRCA 1-Interacting Genes (2011) (7)
Polygenic risk scores for prediction of breast cancer risk in Asian populations (2021) (7)
Common breast cancer risk loci predispose to distinct tumor subtypes (2019) (6)
Breast cancer susceptibility polymorphisms and endometrial cancer risk: a Collaborative Endometrial Cancer Study. (2011) (6)
Publisher Correction: Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation (2018) (6)
Common variants in breast cancer risk loci predispose to distinct tumor subtypes (2022) (6)
Evaluation of chromosome 6p22 as a breast cancer risk modifier locus in a follow-up study of BRCA2 mutation carriers (2012) (6)
Breast cancer risks associated with missense variants in breast cancer susceptibility genes (2021) (6)
Functional annotation of the 2q35 breast cancer risk locus implicates a structural variant in influencing activity of a long-range enhancer element (2021) (6)
The AIB 1 Polyglutamine Repeat Does Not Modify Breast Cancer Risk in BRCA 1 and BRCA 2 Mutation Carriers (2006) (6)
High-throughput allelic expression imbalance analyses identify candidate breast cancer risk genes (2019) (6)
7q21-rs6964587 and breast cancer risk: an extended case–control study by the Breast Cancer Association Consortium (2011) (6)
Evaluation of variation in the phosphoinositide-3-kinase catalytic subunit alpha oncogene and breast cancer risk (2011) (6)
Publisher Correction: Personalized early detection and prevention of breast cancer: ENVISION consensus statement (2020) (6)
Candidate Causal Variants at the 8p12 Breast Cancer Risk Locus Regulate DUSP4 (2019) (6)
Height, selected genetic markers and prostate cancer risk: results from the PRACTICAL consortium (2017) (6)
Characterisation of PALB2 tumours through whole-exome and whole-transcriptomic analyses (2021) (6)
A double blind randomised clinical trial of adjuvant aminoglutethimide versus placebo given to post menopausal patients with histologically confirmed stage II breast cancer. (1986) (6)
Combining genome-wide studies of breast, prostate, ovarian and endometrial cancers maps cross-cancer susceptibility loci and identifies new genetic associations (2020) (6)
Eligibility for MRI screening in the UK: Effect of strict selection criteria and anonymous DNA testing on breast cancer incidence in the MARIBS study (2009) (6)
Application of linked DNA markers to screening families with multiple endocrine neoplasia type 2A. (1990) (6)
Seq4SNPs: new software for retrieval of multiple, accurately annotated DNA sequences, ready formatted for SNP assay design (2009) (6)
Discovery of common and rare genetic risk variants for colorectal cancer (2018) (6)
Prospective validation of the BOADICEA multifactorial breast cancer risk prediction model in a large prospective cohort study (2022) (6)
Large-scale cross-cancer fine-mapping of the 5p15.33 region reveals multiple independent signals (2021) (5)
Erratum: Genome-wide association study identifies multiple loci associated with both mammographic density and breast cancer risk (Nature Communications (2014) 5:5303 (DOI:10.1038/ncomms6303)) (2015) (5)
RAD51D Aberrant Splicing in Breast Cancer: Identification of Splicing Regulatory Elements and Minigene-Based Evaluation of 53 DNA Variants (2021) (5)
Evaluation of the association of heterozygous germline variants in NTHL1 with breast cancer predisposition: an international multi-center study of 47,180 subjects (2021) (5)
Potential of polygenic risk scores for improving population estimates of women’s breast cancer genetic risks (2021) (5)
Cancer risks in A-T heterozygotes. (1994) (5)
Erratum: Corrigendum: A common coding variant in CASP8 is associated with breast cancer risk (2007) (5)
Prostate Cancer Risk by BRCA2 Genomic Regions (2020) (5)
Magnetic resonance imaging in breast screening (MARIBS) study group (2005) (5)
From families to chromosomes: genetic linkage, and other methods for finding cancer-predisposition genes (1996) (5)
Evidence for SMAD 3 as a modifier of breast cancer risk in BRCA 2 mutation carriers (2010) (5)
Genetic Variants in ER Cofactor Genes and Endometrial Cancer Risk (2012) (5)
CYP3A7*1C allele: linking premenopausal oestrone and progesterone levels with risk of hormone receptor-positive breast cancers (2021) (5)
Distinct reproductive risk profiles for intrinsic-like breast cancer subtypes: pooled analysis of population-based studies. (2022) (5)
The genetic epidemiology of ovarian cancer (1995) (5)
Expanded genomic analyses for male voice-breaking highlights a shared phenotypic and genetic basis between puberty timing and hair colour (2018) (5)
Runs of homozygosity and testicular cancer risk (2019) (5)
Correction: Common Genetic Variants and Modification of Penetrance of BRCA2-Associated Breast Cancer (2010) (5)
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (2018) (4)
Should Age-Dependent Absolute Risk Thresholds Be Used for Risk Stratification in Risk-Stratified Breast Cancer Screening? (2021) (4)
Correction: Comparison of 6q25 Breast Cancer Hits from Asian and European Genome Wide Association Studies in the Breast Cancer Association Consortium (BCAC) (2012) (4)
Publisher Correction: Shared heritability and functional enrichment across six solid cancers (2019) (4)
Correction: Corrigendum: Common variants at 19p13 are associated with susceptibility to ovarian cancer (2016) (4)
Incorporating progesterone receptor expression into the PREDICT breast prognostic model. (2022) (4)
The BRCA1 and BRCA2 genes (2004) (4)
Genome-wide and transcriptome-wide association studies of mammographic density phenotypes reveal novel loci (2022) (4)
Candidate locus analysis of the TERT–CLPTM1L cancer risk region on chromosome 5p15 identifies multiple independent variants associated with endometrial cancer risk (2014) (4)
The breast-ovarian cancer syndrome and BRCA1 (1996) (4)
Prognostic value of automated KI67 scoring in breast cancer: a centralised evaluation of 8088 patients from 10 study groups (2016) (4)
Abstract S2-03: Does BRCA status affect outcome in young breast cancer patients? Results from the prospective study of outcomes in sporadic and hereditary breast cancer (POSH) (2017) (4)
Abstract 5065: Fine-mapping theHOXBregion detects common variants tagging a rare coding allele: Evidence for synthetic association in prostate cancer (2014) (4)
Author Correction: Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma (2019) (4)
Re: On the use of familial aggregation in population-based case probands for calculating penetrance. (2003) (4)
Effect of germ-line BRCA mutations in biochemical relapse and survival after treatment for localized prostate cancer. (2013) (4)
Common variants in ZNF 365 are associated with both mammographic density and breast cancer risk (2019) (4)
Risk Analysis of Prostate Cancer in PRACTICAL Consortium—Response (2016) (3)
Association of germline variation with the survival of women with BRCA1/2 pathogenic variants and breast cancer. (2020) (3)
Overexpression of TP53 is Associated with Aggressive Prostate Cancer butdoes not Distinguish Disease in BRCA1 or BRCA2 Mutation Carriers froma Control Group (2009) (3)
AA9int: SNP interaction pattern search using non‐hierarchical additive model set (2018) (3)
Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer (2013) (3)
The Identification of Rare and Common Variants Which Predispose to Prostate Cancer (2010) (3)
Mendelian randomisation study of smoking exposure in relation to breast cancer risk (2021) (3)
The CYP17A1 −34T > C polymorphism and breast cancer risk in BRCA1 and BRCA2 mutation carriers (2011) (3)
Association of germline genetic variants with breast cancer-specific survival in patient subgroups defined by clinic-pathological variables related to tumor biology and type of systemic treatment (2021) (3)
Publisher Correction: Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction (2021) (3)
Association of germline variation with the survival of women with BRCA1/2 pathogenic variants and breast cancer (2020) (3)
Letter to the editor: a response to Ming’s study on machine learning techniques for personalized breast cancer risk prediction (2020) (3)
Erratum: Evaluation of BRCA1 and BRCA2 mutation prevalence, risk prediction models and a multistep testing approach in French-Canadian families with high risk of breast and ovarian cancer (Journal of Medical Genetics (2007) 44, (107-121)) (2007) (3)
Over-expression of RAD 51 occurs in aggressive prostate cancer (2010) (3)
Minigene‐based splicing analysis and ACMG/AMP‐based tentative classification of 56 ATM variants (2022) (3)
Germline HOXB13 mutations p.G84E and p.R217C do not confer an increased breast cancer risk (2020) (3)
Epidemiological and ES cell‐based functional evaluation of BRCA2 variants identified in families with breast cancer (2020) (3)
Genome-wide association meta-analyses combining multiple risk phenotypes provide insights into the genetic architecture of cutaneous melanoma susceptibility (2020) (3)
EXTENDING THE GENETIC-MAP OF THE PERICENTROMERIC REGION OF CHROMOSOME-10 (1991) (3)
Assessment of variation in immunosuppressive pathway genes reveals TGFBR2 to be associated with risk of clear cell ovarian cancer (2016) (3)
Author Correction: Germline variation at 8q24 and prostate cancer risk in men of European ancestry (2019) (3)
From association to cause: fine mapping of the TNRC9 gene region, a novel susceptibility locus identified in the first genome-wide association study for breast cancer (2008) (3)
Predicting the likelihood of carrying a BRCA1 or BRCA2 mutation in Asian breast cancer patients (2022) (3)
Abstract 2598: Predicting breast and ovarian cancer risks for BRCA1 and BRCA2 mutation carriers using polygenic risk scores (2016) (3)
Segregation analysis of 17,425 population-based breast cancer families: Evidence for genetic susceptibility and risk prediction (2022) (3)
Breast cancer risks for BRCA 1/2 carriers [2] (multiple letters) (2004) (3)
A genetic risk score to guide age-specific, personalized prostate cancer screening (2016) (3)
A quantitative portal imaging assessment of set-up discrepancies during radiation therapy for spinal metastases (2004) (2)
Physical activity, sedentary time and breast cancer risk: a Mendelian randomisation study (2022) (2)
Correction: Corrigendum: Genome-wide association study identifies multiple loci associated with both mammographic density and breast cancer risk (2015) (2)
Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction (2021) (2)
Genome- and transcriptome-wide association studies of 386,000 Asian and European-ancestry women provide new insights into breast cancer genetics. (2022) (2)
A Genome-Wide Gene-Based Gene–Environment Interaction Study of Breast Cancer in More than 90,000 Women (2022) (2)
Polymorphisms in In fl ammation Pathway Genes and Endometrial Cancer Risk (2013) (2)
Investigating the genetic relationship between Alzheimer’s disease and cancer using GWAS summary statistics (2017) (2)
The A-T gene does not make a major contribution to familial breast cancer (1993) (2)
Multivariate statistical methods in toxicology: application to the analysis of outpatient clinical data for diphenylhydantoin and phenobarbital in the treatment of epilepsy. (1980) (2)
Abstract 2567: Genetic risk stratification for breast cancer based on a polygenic risk score and family history. (2013) (2)
Mutation analysis of H 19 and NAP 1 L 4 ( hNAP 2 ) candidate genes and IGF 2 DMR 2 in Beckwith-Wiedemann syndrome (2000) (2)
Characterisation of protein-truncating and missense variants in PALB2 in 15 768 women from Malaysia and Singapore (2021) (2)
Genomic analyses for age at menarche identify 389 independent signals and indicate BMI-independent effects of puberty timing on cancer susceptibility (2016) (2)
Abstract P4-06-13: BRCA1/2 mutations identified by screening a large unselected breast cancer cohort in Sweden (2018) (2)
A genome-wide association study to identify genetic markers associated with endometrial cancer grade (2012) (2)
From families to chromosomes: genetic linkage and association studies for finding cancerpredisposition genes (2004) (2)
Response: Re: Pregnancies, Breastfeeding, and Breast Cancer Risk in the International BRCA1/2 Carrier Cohort Study (IBCCS) (2007) (2)
Publisher Correction: Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways (2019) (2)
Abstract 4309: Rare protein truncating and missense variants in ATM, CHEK2, PALB2, but not XRCC2, confer increased breast cancer risks (2016) (2)
Two truncating variants in FANCC and breast cancer risk (2019) (2)
PredictCBC-2.0: a contralateral breast cancer risk prediction model developed and validated in ~ 200,000 patients (2022) (2)
Oral Contraceptive Use in BRCA1 and BRCA2 Mutation Carriers: Absolute Cancer Risks and Benefits (2022) (2)
A preliminary analysis of consortium data for markers tightly linked to multiple endocrine neoplasia type 2A. (1992) (2)
Height, selected genetic markers and prostate cancer risk: results from the PRACTICAL consortium (2017) (2)
Abstract 2030: The role of genetic variation in calcium-activated potassium channels in breast cancer patients treated with tamoxifen (2016) (2)
Body mass index and type 2 diabetes and breast cancer survival: a Mendelian randomization study. (2021) (2)
rs2735383, located at a microRNA binding site in the 3’UTR of NBS1, is not associated with breast cancer risk (2016) (2)
Application of minisatellite DNA probes to linkage in MEN-2. (1987) (2)
E-cadherin breast tumor expression, risk factors and survival: Pooled analysis of 5,933 cases from 12 studies in the Breast Cancer Association Consortium (2018) (2)
Performance of automated scoring of ER, PR, HER2, CK5/6 and EGFR in breast cancer tissue microarrays in the Breast Cancer Association Consortium: Automated scoring of breast tumor TMAs (2014) (2)
Abstract 2565: Prostate cancer GWAS from more than 89,000 men identifies more than 30 novel prostate cancer susceptibility loci (2016) (2)
BRCA1, BRCA2 and pedigree genetic analysis to determine genetic risk in the UK Royal Marsden Hospital tamoxifen prevention trial (2000) (2)
VEXOR: an integrative environment for prioritization of functional variants in fine‐mapping analysis (2017) (2)
Common variants at the CHEK 2 gene locus and risk of epithelial ovarian cancer (2015) (2)
Reproductive profiles and risk of breast cancer subtypes: a multi-center case-only study (2017) (2)
Annexin A 1 expression in a pooled breast cancer series (2)
Author Correction: The evolutionary history of lethal metastatic prostate cancer (2020) (2)
Joint association of mammographic density adjusted for age and body mass index and polygenic risk score with breast cancer risk (2019) (1)
Identification of novel breast cancer susceptibility loci in meta-analyses conducted among Asian and European descendants (2020) (1)
Assessment of polygenic architecture and risk prediction based on common variants across fourteen cancers (2020) (1)
Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants (2018) (1)
Assessment of polygenic architecture and risk prediction based on common variants across fourteen cancers (2020) (1)
Corrigendum: Rare coding variants and X-linked loci associated with age at menarche (2015) (1)
The Genetic Epidemiology of Hereditary Breast Cancer (2007) (1)
Evidence of Novel Susceptibility Variants for Prostate Cancer and a Multiancestry Polygenic Risk Score Associated with Aggressive Disease in Men of African Ancestry. (2023) (1)
Abstract 1650: Overview of the clinical ELLIPSE (ELucidating Loci Involved in Prostate cancer SuscEptibility) Consortium (CEC) (2012) (1)
Polygenic Risk Modelling for Prediction of Epithelial Ovarian Cancer Risk (2020) (1)
Abstract 2174: Identification of genetic factors contributing to development of common cancers through tissue-specific protein interaction analysis (2015) (1)
Permutation Likelihoods for Analysing BRCA2 Genotype‐Phenotype Correlations (1999) (1)
Gene-Environment Interactions Relevant to Estrogen and Risk of Breast Cancer: Can Gene-Environment Interactions Be Detected Only among Candidate SNPs from Genome-Wide Association Studies? (2021) (1)
Rare germline copy number variants (CNVs) and breast cancer risk (2022) (1)
Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia (2018) (1)
Author Correction: Genome-wide association study of classical Hodgkin lymphoma identifies key regulators of disease susceptibility (2019) (1)
Erratum: Risk-reducing salpingo-oophorectomy, natural menopause, and breast cancer risk: An international prospective cohort of BRCA1 and BRCA2 mutation carriers (Breast Cancer Res (2020) 22 (8) DOI: 10.1186/s13058-020-1247-4) (2020) (1)
Prediction and clinical utility of a contralateral breast cancer risk model (2019) (1)
Abstract 870: Analysis of breast cancer risk factors by expression of tumor markers: results of 34 studies in the Breast Cancer Association Consortium (BCAC) (2010) (1)
Fine-Scale Mapping at 9p22.2 Identifies Candidate Causal Variants That Modify Ovarian Cancer Risk in $\small \textit{BRCA1}$ and $\small \textit{BRCA2}$ Mutation Carriers (2016) (1)
Germline breast cancer susceptibility genes, tumor characteristics, and survival (2021) (1)
Lack of mutagenic activity of bile acids in bacterial fluctuation tests. (1987) (1)
Identiﬁcation of four novel susceptibility loci for oestrogen receptor negative breast cancer (2016) (1)
Genetic variation at CYP3A is associated with age at menarche and breast cancer risk: a case-control study (2014) (1)
Abstract 4288: Inherited mutations inBRCA1andBRCA2in an unselected multi-ethnic cohort of Asian breast cancer patients and healthy controls from Malaysia (2017) (1)
Clinicians’ use of breast cancer risk assessment tools according to their perceived importance of breast cancer risk factors: an international survey (2018) (1)
ClinGen and Genetic Testing. (2015) (1)
Identi fi cation of shared and unique susceptibility pathways among cancers of the lung , breast , and prostate from genome-wide association studies and tissue-speci fi c protein interactions (2015) (1)
Abstract 1225: Rare variants in DNA damage repair genes are associated with male breast cancer predisposition (2018) (1)
A comprehensive evaluation of interaction between genetic variants and use of menopausal hormone therapy on mammographic density (2015) (1)
A multilayered post-GWAS assessment on genetic susceptibility to pancreatic cancer (2021) (1)
Abstract 2752: Genetic heterogeneity of ovarian cancer survival effects inBRCA1/2germline mutations: a large, multi-center study (2011) (1)
Non-coding RNAs underlie genetic predisposition to breast cancer (2020) (1)
Corrigendum: A somatic-mutational process recurrently duplicates germline susceptibility loci and tissue-specific super-enhancers in breast cancers (2017) (1)
VEXOR: an integrative environment for prioritization of functional variants in fine-mapping analysis. (2017) (1)
Inheritance of deleterious mutations at both BRCA1 and BRCA2 in an international sample of 32,295 women (2016) (1)
Assessment of variation in immunosuppressive pathway genes reveals TGFBR2 to be associated with prognosis of estrogen receptor-negative breast cancer after chemotherapy (2015) (1)
Abstract 4276: Oral contraceptive use and breast cancer risk: a cohort study ofBRCA1andBRCA2mutation carriers (2017) (1)
Identification of nine new susceptibility loci for endometrial cancer (2018) (1)
Cross-ancestry GWAS meta-analysis identifies six new loci for breast cancer in women of African and European ancestry (2021) (1)
Comment on: On the use of familial aggregation in population-based case probands for calculating penetrance. Authors' reply (2003) (1)
Correction to: Genetic variant predictors of gene expression provide new insight into risk of colorectal cancer (2019) (1)
Correction: Polygenic risk modeling for prediction of epithelial ovarian cancer risk (2022) (1)
Acne and Prostate Cancer Risk. (2014) (1)
Abstract 2780: Evaluation of genetic variants in high and moderate-penetrance breast cancer susceptibility genes in East Asians (2015) (1)
Copy number variants as modifiers of breast cancer risk for BRCA1/BRCA2 pathogenic variant carriers (2022) (1)
Genome-wide and transcriptome-wide association studies of mammographic density phenotypes reveal novel loci (2022) (1)
COMPLEXO: identifying the missing heritability of breast cancer via next generation collaboration (2013) (1)
Genetic variant predictors of gene expression provide new insight into risk of colorectal cancer (2019) (1)
Genetic predisposition to ductal carcinoma in situ of the breast (2016) (1)
CanRisk-Prostate: A Comprehensive, Externally Validated Risk Model for the Prediction of Future Prostate Cancer (2022) (1)
Abstract 5314: DNA methylation quantitative trait loci and breast cancer risk: Data from nearly 230,000 women of European descent (2018) (1)
Optimal sampling strategies for detecting linkage of a complex trait with known genetic heterogeneity (1994) (1)
A network analysis to identify mediators of germline-driven differences in breast cancer prognosis (2020) (1)
Genetic variation in the immunosuppression pathway genes and breast cancer susceptibility: a pooled analysis of 42,510 cases and 40,577 controls from the Breast Cancer Association Consortium (2015) (1)
Common Polymorphisms in ERCC 2 ( Xeroderma pigmentosum D ) are not Associated with Breast Cancer Risk (2005) (1)
Rare, protein-truncating variants in $\textit{ATM}$, $\textit{CHEK2}$ and $\textit{PALB2}$, but not $\textit{XRCC2}$, are associated with increased breast cancer risks (2017) (1)
Associations of a Breast Cancer Polygenic Risk Score With Tumor Characteristics and Survival (2022) (1)
Sampling distribution of summary linkage disequilibrium measures. (2002) (1)
A population-based audit of ethnicity and breast cancer risk in one general practice catchment area in North London, UK: implications for practice (2007) (1)
Identifying 31 novel breast cancer susceptibility loci using data from genome-wide association studies conducted in Asian and European women (2019) (1)
Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma (2018) (1)
Corrigendum: A common coding variant in CASP8 is associated with breast cancer risk (2007) (1)
Human Lung Cancer Somatic Mutations of the Protein Kinase Gene Family in Updated (2005) (1)
Prediction of breast cancer risk based on common genetic variants in women of East Asian ancestry (2016) (1)
Breast Cancer Risk and 6 q 22 . 33 : Combined Results from Breast Cancer Association Consortium and Consortium of Investigators on Modifiers of BRCA 1 / 2 (2012) (1)
Effects of BRCA2 cis-regulation in normal breast and cancer risk amongst BRCA2 mutation carriers (2012) (1)
Applying Mendelian randomization to appraise causality in relationships between smoking, depression and inflammation (2022) (1)
Null Results in Brief Common Genetic Variation at BARD 1 Is Not Associated with Breast Cancer Risk in BRCA 1 or BRCA 2 Mutation Carriers (2011) (1)
Is the Association Between Smoking and Depression Mediated by Inflammation? A Mendelian Randomization Study. (2021) (1)
Reply: Remarks on the BOADICEA model of genetic susceptibility to breast and ovarian Cancer Research UK (2005) (1)
Uncovering the Contribution of Moderate-Penetrance Susceptibility Genes to Breast Cancer by Whole-Exome Sequencing and Targeted Enrichment Sequencing of Candidate Genes in Women of European Ancestry (2022) (1)
Corrigendum re "Genetic Variants Related to Longer Telomere Length are Associated with Increased Risk of Renal Cell Carcinoma" [Eur Urol 2017;72:747-54]. (2018) (1)
Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution (2019) (1)
Pubertal development and prostate cancer risk (2018) (1)
Common variants at the CHEK2 gene locus and risk of epithelial ovarian cancer. (2015) (1)
Circulating vitamin D concentrations and risk of breast and prostate cancer: a Mendelian randomization study (2019) (1)
RELATION BETWEEN BREAST TUMOUR GROWTH RATE AND METASTATTC POTENTIAL (1986) (1)
Genome-wide association study of germline variants and breast cancer-speci fi c mortality (2019) (1)
EBCC-13 manifesto: Balancing pros and cons for contralateral prophylactic mastectomy. (2022) (1)
Bromodomain protein 4 discriminates tissue-specific super-enhancers containing disease-specific susceptibility loci in prostate and breast cancer (2017) (1)
BRCA 1 / BRCA 2 prediction model (2004) (1)
Influence of cytokine polymorphisms on susceptibility to and/or prognosis in prostate cancer (2002) (1)
Author Correction: Pan-cancer analysis of whole genomes (2023) (1)
Validation of prostate cancer risk-related loci identified from genome-wide association studies using family-based association analysis: evidence from the International Consortium for Prostate Cancer Genetics (ICPCG) (2011) (1)
The search for low-penetrance breast cancer genes (2005) (1)
Breast cancer susceptibility after BRCA1/2: finding the genes and potential practical applications (2006) (1)
Oral contraceptives and breast cancer risk in the International BRCA1/2 Carrier Cohort Study (IBCCS) (2005) (1)
Using human genetics to understand the disease impacts of testosterone in men and women (2020) (1)
Informed consent for observational research in children (1996) (0)
moderate penetrance gene contributing to young-onset prostate cancer: implications for genetic testing in prostate cancer patients, British Journal of Cancer, Vol. 105(8), 1230-1234 BRCA2 is a moderate penetrance gene contributing to young-onset prostate cancer: implications for genetic testing in p (2015) (0)
POLYMORPHISMS IN DNA REPAIR GENES AND OVARIAN CANCER SUSCEPTIBILITY (2003) (0)
Abstract 4836: Gene and environment interactions of height and selected candidate SNPs in prostate cancer: results from the PRACTICAL consortium. (2013) (0)
Inherited mutations in BRCA1 and BRCA2 in an unselected multi-ethnic cohort of Asian breast cancer patients and healthy controls from Malaysia (2017) (0)
Applying Mendelian randomization to appraise causality in relationships between smoking, depression and inflammation (2022) (0)
CHEK 2 , MGMT , SULT 1 E 1 and SULT 1 A 1 Polymorphisms and Endometrial Cancer Risk (2011) (0)
O-58 The UK MARIBS study of MRI breast screening: progress on genetic and density projects (2007) (0)
A Novel Tumour-Based Test To Identify Breast Cancer Due to BRCA1 and BRCA2 Mutations. (2009) (0)
Inherited predisposition to ovarian cancer ‐ the contribution of mutations in BRCA1 (1998) (0)
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (2019) (0)
New Results in Susceptibility to Breast Cancer and their Implications (2007) (0)
PRACTICAL (2016). Blood lipids and prostate cancer: a Mendelian randomization analysis. (2016) (0)
Authors' response: associations of obesity and circulating insulin and glucose with breast cancer risk. (2019) (0)
First international workshop of the ATM and cancer risk group (4-5 December 2019) (2021) (0)
Polygenic risk modeling for prediction of epithelial ovarian cancer risk (2022) (0)
and Is Associated with Increased Incidence of Invasive Breast Cancer A Transforming Growth Factor{beta}1 Signal Peptide Variant Increases Secretion in Vitro (2010) (0)
1. The Genetics of Testicular Germ Cell Tumours (2002) (0)
Abstract 4495: Clinical implications of family history of prostate cancer in an active surveillance cohort (2012) (0)
Overexpression of TP 53 is Associated with Aggressive Prostate Cancer but does not Distinguish Disease in BRCA 1 or BRCA 2 Mutation Carriers from a Control Group (2009) (0)
Annexin A1 expression in breast cancer: tumor subtypes and prognosis (2015) (0)
Male breast cancer in BRCA1 and BRCA2 mutation carriers (2018) (0)
Publisher Correction: Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways (2019) (0)
Publisher Correction: Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction (2021) (0)
Reply: ‘Hand pattern indicates risk of prostate cancer’ (2011) (0)
Patient survival and tumor characteristics associated with CHEK2:p.I157T – findings from the Breast Cancer Association Consortium (2016) (0)
Abstract 28: Integrating genomic and transcriptomic data to identify genetic loci associated with breast cancer risk in women of African ancestry (2020) (0)
Breast cancer risk in women from Ghana carrying rare germline pathogenic mutations. (2022) (0)
[The genetics of medullary cancer of the thyroid]. (1988) (0)
The use of germline genetic markers in the androgen receptor gene to identify individuals at increased risk of prostate cancer relapse (1998) (0)
Use of the BOADICEA breast cancer risk prediction tool in clinical practice: Appraisals across clinicians from various countries (2017) (0)
Title: Sex Specific Associations in Genome Wide Association Analysis of Renal Cell Carcinoma (2019) (0)
CYP3A7*1C allele: linking premenopausal oestrone and progesterone levels with risk of hormone receptor-positive breast cancers (2021) (0)
Title Interplay between BRCA 1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer (2012) (0)
Fine-mapping identifies multiple prostate cancer risk loci on 5p15 some associating with TERT expression (2013) (0)
Blood lipids and prostate cancer: a Mendelian randomization analysis PRACTICAL consortium (2020) (0)
Title Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer (2017) (0)
Author Correction: Inferring structural variant cancer cell fraction (2022) (0)
The architecture of clonal expansions in morphologically normal tissue from cancerous and non-cancerous prostates (2022) (0)
Correction to: Risk-reducing salpingo-oophorectomy, natural menopause, and breast cancer risk: an international prospective cohort of BRCA1 and BRCA2 mutation carriers (2020) (0)
Genetics and population analysis pedigreejs: a web-based graphical pedigree editor (2017) (0)
Refined histopathological predictors of BRCA1 and BRCA2mutation status: a large-scale analysis of breast cancer characteristics from the BCAC, CIMBA, and ENIGMA consortia (2014) (0)
Adjuvant aminoglutethimide for post-menopausal women with primary breast cancer: Analysis of eight years (1992) (0)
breast Cancer Markers (2006) (0)
P1-46 Diagnostic radiation exposure and breast cancer risk in BRCA1/2 mutation carriers in the gene-rad-risk study (2011) (0)
Drug repositioning opportunities for breast cancer prevention and treatment (2019) (0)
Letters to the Editor (0)
Author Correction: Germline variation at 8q24 and prostate cancer risk in men of European ancestry (2019) (0)
SNP rs2180341 per-allele hazard ratios (HRs) and 95% confidence intervals (CIs) among Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA) in A. BRCA1 mutation carriers B. BRCA2 mutation carriers. (2012) (0)
Correction to: Risk-reducing salpingo-oophorectomy, natural menopause, and breast cancer risk: an international prospective cohort of BRCA1 and BRCA2 mutation carriers (2020) (0)
Correction to: Genetic variant predictors of gene expression provide new insight into risk of colorectal cancer (2019) (0)
Shared heritability and functional enrichment across six solid cancers (2019) (0)
The impact of coding germline variants on contralateral breast cancer risk and survival (2023) (0)
Association analyses identify 31 new risk loci for colorectal cancer susceptibility (2019) (0)
Markers of breast cancer (2006) (0)
Nucleotide Polymorphisms and Risk of Breast Cancer Gene Single Hyaluronan-Mediated Motility Receptor (2008) (0)
More on Co-Occurrence of COMT and BRCA1/2 Variants in a Population. (2017) (0)
Author Correction: Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci (2019) (0)
Abstract 943: A comprehensive examination of breast cancer risk loci in African American women (2014) (0)
Letter to the editor: a response to Ming’s study on machine learning techniques for personalized breast cancer risk prediction (2020) (0)
gene mutation in the fibroblast growth factor receptor 3 hypochondroplasia owing to a novel Asn 540 Ser Clinical and radiographic features of a family with (2000) (0)
Germline variation at 8q24 and prostate cancer risk in men of European ancestry (2018) (0)
Ovarian cancer pathology characteristics as predictors of variant pathogenicity in BRCA1 and BRCA2. (2023) (0)
Multiplicative and additive gene-environment interaction between common breast cancer susceptibility loci and established environmental risk factors (2013) (0)
GENOME-WIDE ASSOCIATION STUDY OF HODGKIN LYMPHOMA IDENTIFIES HISTOLOGY-SPECIFIC ASSOCIATIONS AND TRANSCRIPTIONAL REGULATORS OF DISEASE SUSCEPTIBILITY (2017) (0)
Identifying new breast cancer susceptibility genes (2002) (0)
2 The genetics of malignant melanoma (1997) (0)
A systemic study of polymorphisms in mismatch repair genes and predisposition to ovarian cancer. (2005) (0)
Abstract 2211: Patient level polygenic risk scores and continuous estrogen receptor expression in breast cancer (2018) (0)
An original phylogenetic approach identified mitochondrial haplogroup T1a1 as inversely associated with breast cancer risk in BRCA2 mutation carriers (2015) (0)
Correction: Polygenic risk modeling for prediction of epithelial ovarian cancer risk (2022) (0)
Abstract 3182: A GWAS-based cross-disease approach suggests genes predisposing to risk of endometriosis and endometrial cancer. (2013) (0)
Chromatin interactome mapping at 139 independent breast cancer risk signals (2020) (0)
Contributors and Participants (1982) (0)
Low-dose ionizing radiation significantly increases the risk of breast cancer among BRCA1/2 mutation carriers in the International BRCA1/2 Carrier Cohort Study (IBCCS) (2005) (0)
Results in Brief Association between FTO or HHEX and Endometrial B & P cer Risk (2010) (0)
The PROFILE feasibility study: Genetic prostate cancer risk stratification for targeted screening. (2014) (0)
Null Results in Brief Cancer Epidemiology , Biomarkers & Prevention A Genome-Wide Association Study of Prognosis in Breast Cancer (2010) (0)
Cancers oftherespiratory tract inmustard gas workers (1988) (0)
Abstract 2842: Gene expression and genetic variation of the matrix metalloproteinase family: evidence for association with endometrial cancer risk and prognosis (2010) (0)
Abstract 4249: High-Frequency of TMPRSS2-ERG fusion gene identifies a non-random androgen-driven event of chromosomal instability in BRCA mutated prostate cancer (2015) (0)
Abstract 2850: Endometrial cancer and genetic variation in PTEN, PIK3CA, AKT1, MLH1, and MSH2: results and replication in two case-control studies (2010) (0)
Polygenic Risk Scores for Prediction of Breast Cancer Risk in Women of African Ancestry: a Cross-Ancestry Approach (2021) (0)
Relevance of the MHC region for breast cancer susceptibility in Asians (2022) (0)
Abstract 1309: Association between insulin resistance and breast cancer risk: A Mendelian randomization analysis of data from 228,000 women of European descent (2017) (0)
A genetic hazard score to personalize prostate cancer screening, applied to population data (2019) (0)
Genetic variation in the immunosuppression pathway genes and breast cancer: a pooled analysis of 42,510 cases and 40,577 controls from the Breast (2015) (0)
Bristol Cancer Help Centre (1990) (0)
Association analysis of 9,560 prostate cancer cases from the International Consortium of Prostate Cancer Genetics confirms the role of reported prostate cancer associated SNPs for familial disease (2013) (0)
Genome analysis AA 9 int : SNP Interaction Pattern Search Using Non-Hierarchical Additive Model Set (2018) (0)
Abstract 230: Joint genome-wide association study of endometrial cancer and ovarian cancer identifies a novel genetic risk region at 14q23.3 (2018) (0)
Abstract 3810: BRCA2 is a moderate penetrance gene contributing to young onset prostate cancer, but not disease over 65 years (2011) (0)
Hand pattern and early-onset prostate cancer risk (2010) (0)
Genomic risk factors for cervical cancer: current status of the Cervigen study (2022) (0)
Author Correction: Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma (2019) (0)
Clinical implications of a prostate cancer risk SNP profile in two treatment cohorts. (2013) (0)
Low penetrance susceptibility genes for breast cancer (2001) (0)
Abstract 1420: Prevalence ofPALB2mutations in an unselected cohort of breast cancer patients and unaffected individuals from Malaysia and Singapore (2018) (0)
The editor wishes to acknowledge the collaboration of the following colleagues as referees for JECH during 1997-98. (1999) (0)
Characterisation of PALB2 tumours through whole-exome and whole-transcriptomic analyses (2021) (0)
Abstract 642: Body fat distribution and prostate cancer risk: A UK case-control study (2012) (0)
1212 POSTER Testicular germ cell tumour and testicular microlithiasis; a familial association? (2007) (0)
Common variants in breast cancer risk loci predispose to distinct tumor subtypes (2022) (0)
A polymorphism in the base excision repair gene PARP2 is associated with differential prognosis by chemotherapy among postmenopausal breast cancer patients (2015) (0)
Genetic predisposition to mosaic Y chromosome loss in blood (2019) (0)
The FANCM:p.Arg658* truncating variant is associated with risk of triple-negative breast cancer (2019) (0)
Genome-wide association study of endometrial cancer in E2C2 (2013) (0)
Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer (2019) (0)
Using Data Validation to Improve a Clinical Cancer Registry (2014) (0)
Corrections to: Use of the BOADICEA Web Application in clinical practice: appraisals by clinicians from various countries (2017) (0)
the Breast Cancer Association Consortium Five Polymorphisms and Breast Cancer Risk : Results from Updated (2009) (0)
Abstract 5742: Hand pattern and prostate cancer risk (2010) (0)
Exploring the barriers and facilitators of implementing CanRisk in primary care: a qualitative thematic framework analysis (2023) (0)
Alcohol consumption and prostate cancer incidence and progression: A Mendelian randomisation study. (1), (2016) (0)
A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer (2018) (0)
Germline breast cancer susceptibility genes, tumor characteristics, and survival (2021) (0)
133P Using breast cancer risk factors of women to estimate incidence of breast cancer in their sisters (2022) (0)
BRCA carrier status as an independent prognostic factor associated with earlier biochemical relapse in local prostate cancer. (2012) (0)
blood pressure in the HERITAGE Family Study gene-race interactions for resting and exercise (2012) (0)
Association of tamoxifen use and reduced risk of contralateral breast cancer for BRCA1 and BRCA2 mutation carriers (2012) (0)
Genome-wide association study of susceptibility loci for breast cancer in Sardinian population (2015) (0)
The association between Polygenic Risk Scores and contralateral breast cancer risk in BRCA1 and BRCA2 mutation carriers: Analyses in the CIMBA consortium (2018) (0)
Correction: BOADICEA: a comprehensive breast cancer risk prediction model incorporating genetic and nongenetic risk factors (2019) (0)
sense Variants in ATM in 26 , 101 Breast Cancer B & P es and 29 , 842 Controls (2010) (0)
The Genetics Feature Article of Familial Breast Cancer and Their Practical Implications (1994) (0)
Correction: Evaluating Genome-Wide Association Study-Identified Breast Cancer Risk Variants in African-American Women (2014) (0)
Mammographic density and breast cancer risk in germline BRCA1/2 mutation-carriers (2005) (0)
Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets (2018) (0)
The effect of sample size on polygenic hazard models for prostate cancer (2020) (0)
Genome-Wide LinkageAnalysis of 1 , 233 Prostate Cancer Pedigrees Fromthe International Consortium for ProstateCancerGeneticsUsingNovel sumLINKandsumLODAnalyses (2010) (0)
Association of genetic susceptibility variants for type 2 diabetes with breast cancer risk in women of European ancestry (2016) (0)
Sex specific associations in genome wide association analysis of renal cell carcinoma (2019) (0)
Use of oral contraceptives and risk of breast cancer in BRCA1/2 mutation carriers (2004) (0)
Ovarian Cancer Control Genes and Susceptibility to Invasive Epithelial Tagging Single Nucleotide Polymorphisms in Cell Cycle (2007) (0)
Copy Number Variants Are Ovarian Cancer Risk Alleles at Known and Novel Risk Loci (2022) (0)
Breast Cancer Risk in Women from Ghana Carrying Rare Germline Pathogenic Mutations: A Resource for Genetic Counseling of West African Women (2021) (0)
Abstract 2258: Genome-wide association studies of breast cancer prognosis (2017) (0)
P2-250 Omega 3 polyunsaturated fatty acids (PUFAs) and risk of early onset prostate cancer (2011) (0)
Use of the BOADICEA Web Application in clinical practice: appraisals by clinicians from various countries (2017) (0)
Family history of breast cancer [1] (multiple letters) (2005) (0)
Refined histopathological predictors of BRCA1 and BRCA2 mutation status: a large-scale analysis of breast cancer characteristics from the BCAC, CIMBA, and ENIGMA consortia | NOVA. The University of Newcastle's Digital Repository (2014) (0)
338 Genetic susceptibility to breast cancer – new developments and clinical application (2009) (0)
Aggregation tests identify new gene associations with breast cancer in populations with diverse ancestry (2023) (0)
Linkage analysis in non-Mendelian disorders. (1989) (0)
Abstract 2612: The PROFILE study; Germline genetic profiling: Correlation with targeted prostate cancer screening and treatment (2012) (0)
Breast cancer risks associated with missense variants in breast cancer susceptibility genes (2022) (0)
Genome-wide association study of classical Hodgkin lymphoma identifies key regulators of disease susceptibility (2017) (0)
Author Correction: A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers (2021) (0)
Genome-wide association study of germline variants and breast cancer-speci ﬁ c mortality (2019) (0)
Author Correction: Patterns of somatic structural variation in human cancer genomes (2020) (0)
Associations between mammographic density and phytoestrogens (2011) (0)
38 The COGS (Collaborative Oncological Gene-environment Study): Progress and Results (2012) (0)
Abstract 2783: Common functional mechanisms underlying pleiotropy at the 19p13.1 breast and ovarian cancer cusceptibility locus (2015) (0)
A gap analysis for breast cancer research: identifying translational priorities (2013) (0)
ociation of the Variants CASP 8 D 302 H and CASP 10 0 I with Breast and Ovarian Cancer Risk in B & P A 1 and BRCA 2 Mutation Carriers (2010) (0)
Correction to: Overlapping genetic architecture between Parkinson disease and melanoma (2020) (0)
Abstract 758: The clinical utility of BRCA1/2 pathogenic variants in breast cancer patient prognosis (2021) (0)
Correction: PredictCBC-2.0: a contralateral breast cancer risk prediction model developed and validated in ~ 200,000 patients (2022) (0)
Abstract 956: The evolutionary history of lethal metastatic prostate cancer (2015) (0)
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (2018) (0)
OP-JNCI200131 434..442 (2021) (0)
Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses (2020) (0)
Male breast cancer in BRCA1 and BRCA2 mutation carriers: pathology data from the Consortium of Investigators of Modifiers of BRCA1/2 (2016) (0)
HxGN Live! 2014 – Andy Wells Reports from Las Vegas (2014) (0)
ERDAS IMAGINE Transforms the way Rezatec Analyses EO Data (2014) (0)
FME International User Conference 2014 Round-up (2014) (0)
Sterling Geo Attracts Interest from Global Geo Community (2014) (0)
A response to “Personalised medicine and population health: breast and ovarian cancer” (2019) (0)
q 31 . 2 and in ZNF 365 are associated with breast cancer risk for BRCA 1 and / or BRCA 2 mutation carriers (2012) (0)
Polygenic Risk Scores for Prediction of Breast Cancer in Korean women (2021) (0)
Fletcher’s trolley—Alive and well (1983) (0)
Intergraph Geospatial in 2014 (2014) (0)
New for the 2013 UGM! The Innovation Centre (2013) (0)
The Satellite Applications Catapult Road Show (2013) (0)
Abstract 3222: Evaluation of associations between circulating proteins and breast cancer risk using genetic variants (2018) (0)
Are you Ready to Take the Challenge (2014) (0)
Aibotix Fly their UAV at our UGM (PICTURES) (2013) (0)
News from InterGEO 2014 in Berlin (2014) (0)
IMAGINE Spatial Modeler Maps Flooded Areas Captured on Landsat 8 (2014) (0)
Common variants at theCHEK2gene locus and risk of epithelial ovarian cancer (2015) (0)
Abstract P5-08-09: Use of oral contraceptives and risk of breast cancer inBRCA1andBRCA2mutation carriers: An international prospective cohort study; for the studies of EMBRACE, GENEPSO, HEBON, kConFab and BCFR (2017) (0)
Which Events are Sterling Geo Attending in 2014 (2014) (0)
Risks of breast or ovarian cancer in BRCA1 or BRCA2 predictive test negatives: findings from the EMBRACE study (2018) (0)
The Complete List of New Features in the 2015 FME Release (2015) (0)
VIDEO: FME and the ERDAS IMAGINE's Spatial Modeler can be Linked Together using Python Script (2014) (0)
Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci (2018) (0)
Author Correction: Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia (2019) (0)
Association between Common Germline Genetic Variation in 84 Candidate Genes/Regions and Risks of Ovarian Cancer. (2009) (0)
Cross-cancer genome-wide association analysis of lung, ovary, breast, prostate and colon cancer identifies a novel cancer locus at 1q22 (2015) (0)
Abstract PL02-05: New insights into genetic susceptibility to breast cancer (2010) (0)
Johnnie Shannon's Favourite 2015 Features (2015) (0)
UGM 2014: Announcing the 360 Degree Igloo (2014) (0)
Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes (2020) (0)
Null Results in Brief Hyaluronan-Mediated Motility Receptor Gene Single Nucleotide Polymorphisms and Risk of Breast Cancer (2008) (0)
Dietary Phytoestrogen Scoring Database for Prostate Cancer Studiesand Their Role in Prostate Cancer Risk (2011) (0)
Abstract 5483: CYP19A1 genetic variation is a potential predictor of outcome in ER-positive postmenopausal early breast cancer patients treated with tamoxifen (2015) (0)
rs 2735383 , located at a microRNA binding site in the 3 ’ UTR of NBS 1 , is not associated with breast cancer risk (2016) (0)
Abstract 3862: Identification of a novel genetic variant in theKLK3gene which predisposes to prostate cancer (2010) (0)
The Full List of Exciting new Changes in the 2014 Intergraph Release (2013) (0)
AD51B in Familial Breast Cancer (2016) (0)
8. Localization of BRCA2 to chromosome 13Q12-13 by genetic linkage analysis (1995) (0)
Contribution of germline TP53 variants and assessment of HER-2 status among young breast cancer patients in Malaysia (2017) (0)
Anorectal physiology and disease T 120-T 125 T 118 T 120 METABOLITES OF NITRIC OXIDE IN SEVERE ACUTE ULCERATIVE COLITIS (2006) (0)
Correction to: Clinicians’ use of breast cancer risk assessment tools according to their perceived importance of breast cancer risk factors: an international survey (2019) (0)
Genome-wide association study of endometrial cancer in E2C2 access benefits you. Your story matters (2014) (0)
8 The inherited basis of malignant melanoma (1999) (0)
Genomic analysis of male puberty timing highlights shared genetic basis with hair colour and lifespan (2020) (0)
A novel tumour-based test to identify breast cancer due to BRCA1 and BRCA2 mutations (2010) (0)
The admixture maximum likelihood test to test for association between rare variants and disease phenotypes (2013) (0)
Proactive breast cancer risk assessment in primary care: a review based on the principles of screening (2023) (0)
Genomic risk prediction of coronary artery disease in women with breast cancer: a prospective cohort study (2021) (0)
FANCM missense variants and breast cancer risk: a case-control association study of 75,156 European women. (2023) (0)
association studies cancer and the effect of control selection on genetic Genetic variation in protein specific antigen detected prostate (2014) (0)
Abstract B76: Evidence of a causal association between fasting insulin concentrations and endometrial cancer: A Mendelian randomization analysis (2012) (0)
TITLE : Incorporating Truncating Variants in PALB 2 , CHEK 2 and ATM into the BOADICEA Breast Cancer Risk Model SHORT TITLE : Rare Variants in the BOADICEA Breast Cancer Risk Model Authorship (2016) (0)
Evaluation of the association of heterozygous germline variants in NTHL1 with breast cancer predisposition: an international multi-center study of 47,180 subjects (2021) (0)
Genome-wide association study of germline variants and breast cancer-specific mortality (2019) (0)
Abstract P4-06-15: Targeted sequencing ofBRCA1/2across a large unselected breast cancer cohort in Sweden (2018) (0)
Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways (2018) (0)
Radiation for painful bone metastases: Comparison of different measures of palliative response (2004) (0)
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (2018) (0)
Ageing & cancer susceptibility: Is systemic failure of apoptosis a factor? (2002) (0)
Association of the CHEK2 c.1100delC variant, radiotherapy, and systemic treatment with contralateral breast cancer risk and breast cancer-specific survival (2023) (0)
431 Diagnostic radiation exposure and risk of breast cancer in BRCA1/2 mutation carriers in the GENE-RAD-RISK study: a report from the GENEPSO, EMBRACE, and HEBON Collaborators' group (2010) (0)
Rare germline copy number deletions of likely functional importance are implicated in endometrial cancer predisposition (2014) (0)
An Improved Polygenic Risk Score for Risk Prediction in Breast Cancer (2017) (0)
Rare copy number variants (CNVs) and breast cancer risk (2021) (0)
Abstract 962: Validation of breast cancer risk model incorporating classical risk factors and polygenic risk scores in 14 prospective cohort studies in 6 countries (2019) (0)
Association of tamoxifen use and reduced risk of contralateral breast cancer for BRCA1 and BRCA2 mutation carriers (2012) (0)
Short Report Investigating the possible causal role of coffee consumption with prostate cancer risk and progression using Mendelian randomization analysis (2019) (0)
Session 3 S7. Identifying new breast cancer susceptibility genes (2002) (0)
A genome-wide association study to identify genetic markers associated with endometrial cancer grade (2012) (0)
A practical guide to human cancer genetics: S.V. Hodgson and E.R. Maher Cambridge university press, 1993. £45.00 hbk/£19.95 phk (258 pages) isbn 0 521 10128 3 (1993) (0)
Risk of breast or ovarian cancer in family members who do not carry the BRCA1 or BRCA2 family mutation: Findings from the EMBRACE study. (2017) (0)
Author Correction: Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia (2019) (0)
Genome-wide association study of subtype-specific epithelial ovarian cancer risk alleles using pooled DNA (2013) (0)
Linkage analysis ofBritish andIndian families with VonRecklinghausen neurofibromatosis (1987) (0)
Fine-mapping identifies two additional susceptibility 9q31.2. (2015) (0)
Two ATM variants, IVS10-6T>G and 1420L>F, and breast cancer risk (2005) (0)
Short Communication Common Polymorphisms in Checkpoint Kinase 2 Are not Associated with Breast Cancer Risk (2003) (0)
Genome-wide association study and functional follow-up identify 14q12 as a candidate risk locus for cervical cancer (2022) (0)
Associations between breast density and bone density among post-menopausal women (2011) (0)
In reply [4] (2006) (0)
Germline variants and breast cancer survival in patients with distant metastases at primary breast cancer diagnosis (2021) (0)
Incorporating Alternative Polygenic Risk Scores into the BOADICEA Breast Cancer Risk Prediction Model (2022) (0)
Common germline polymorphisms associated with breast cancer-specific survival (2015) (0)
of sample on polygenic hazard models for prostate cancer. (2020) (0)
PLOS ONE Polymorphisms of an Innate Immune Gene, Toll-Like Receptor 4, and Aggressive Prostate Cancer Risk: A Systematic Review and Meta-analysis (2014) (0)
Abstract P1-09-04: Association between a breast cancer polygenic risk score and contralateral breast cancer risk (2019) (0)
Author Correction: Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples (2020) (0)
Genes, chromosomes and disease (2009) (0)
Abstract 5066: Generalizability of established prostate cancer risk variants in men of African ancestry (2014) (0)
Abstract 4606: Fine mapping of 64 prostate cancer GWAS regions identifies multiple novel association signals (2015) (0)
IDENTIFYING GENETIC VARIANTS ASSOCIATED WITH INCREASED RISKS OF EPITHELIAL OVARIAN CANCER (2004) (0)
BOADICEA: a comprehensive breast cancer risk prediction model incorporating genetic and nongenetic risk factors (2019) (0)
Abstract 5570: Heterogeneity of luminal breast cancer characterized by immunohistochemical expression of basal markers (2015) (0)
Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus (2016) (0)
Breast-Cancer Risk in Families With Mutations in PALB2 EDITORIAL COMMENT (2014) (0)
Chapter 1 The genetic epidemiology of ovarian cancer (0)
Influence of aetiological factors for breast cancer on outcome after diagnosis (2005) (0)
Tamoxifen and risk of contralateral breast cancer for \textitBRCA1 and \textitBRCA2 mutation carriers (2013) (0)
a novel candidate breast cancer susceptibility locus on (2017) (0)
Association of rs12662670 with breast cancer in Asian ER (2012) (0)
Null Results in Brief Cancer Epidemiology , Biomarkers & Prevention No Association between TERT-CLPTM 1 L Single Nucleotide Polymorphism rs 401681 and Mean Telomere Length or Cancer Risk (2010) (0)
Author Correction: The evolutionary history of 2,658 cancers (2023) (0)
Association of breast cancer risk in BRCA 1 and BRCA 2 mutation carriers with genetic variants showing differential allelic expression (2016) (0)
Genome-wide interaction analysis of menopausal hormone therapy use and breast cancer risk among 62,370 women (2021) (0)
NIHMS662581-supplement-Supplementary data (2016) (0)
Genetic and immunohistopathological evaluation of BRCA1 and BRCA2 unclassified variants (2005) (0)
Abstract 2271: Pathway analysis suggests biological processes driven by germline genetic associations with breast cancer prognosis (2018) (0)
Associations of common breast cancer susceptibility alleles with risk of breast cancer subtypes in BRCA1 and BRCA2 mutation carriers (2014) (0)
Prostate Cancer BioResource, The UK Genetic Prostate Cancer Study Collaborators ‡ , The UK ProtecT Study Collaborators ‡ , Mathew Freedman 52 , (2015) (0)
The Potential Role of Common Polymorphisms in Predisposition to Breast and Ovarian Cancer (1996) (0)
Corrections to: Use of the BOADICEA Web Application in clinical practice: appraisals by clinicians from various countries (2017) (0)
Author Correction: Genome-wide association study of classical Hodgkin lymphoma identifies key regulators of disease susceptibility (2019) (0)
University of Groningen DNA Glycosylases Involved in Base Excision Repair May Be Associated with Cancer Risk in BRCA1 and BRCA2 Mutation Carriers Osorio, (2014) (0)

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