Douglas Koshland
#64,656
Most Influential Person Now
American biochemist
Douglas Koshland's AcademicInfluence.com Rankings
Douglas Koshlandbiology Degrees
Biology
#3857
World Rank
#5845
Historical Rank
#1522
USA Rank
Biochemistry
#2062
World Rank
#2205
Historical Rank
#301
USA Rank
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Biology
Douglas Koshland's Degrees
- PhD Biochemistry University of California, Berkeley
- Bachelors Biochemistry University of California, Berkeley
Why Is Douglas Koshland Influential?
(Suggest an Edit or Addition)According to Wikipedia, Douglas E. Koshland is a professor of molecular and cellular biology at the University of California, Berkeley. Biography Koshland is the son of Marian and Daniel E. Koshland Jr. He earned his B.A. in chemistry from Haverford College and his Ph.D. in microbiology from Massachusetts Institute of Technology under the guidance of David Botstein. He then did his postdoctoral work with Leland Hartwell at University of Washington and with Marc Kirschner at the University of California, San Francisco.
Douglas Koshland's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- A Direct Link between Sister Chromatid Cohesion and Chromosome Condensation Revealed through the Analysis of MCD1 in S. cerevisiae (1997) (862)
- Anaphase initiation in Saccharomyces cerevisiae is controlled by the APC-dependent degradation of the anaphase inhibitor Pds1p. (1996) (861)
- DNA damage response pathway uses histone modification to assemble a double-strand break-specific cohesin domain. (2004) (591)
- Non-genetic individuality: chance in the single cell (1976) (538)
- Ctf7p is essential for sister chromatid cohesion and links mitotic chromosome structure to the DNA replication machinery. (1999) (485)
- Genome-Wide Mapping of the Cohesin Complex in the Yeast Saccharomyces cerevisiae (2004) (447)
- Evidence that the MIF2 gene of Saccharomyces cerevisiae encodes a centromere protein with homology to the mammalian centromere protein CENP-C. (1995) (446)
- A Molecular Determinant for the Establishment of Sister Chromatid Cohesion (2008) (444)
- Pds1p, an inhibitor of anaphase in budding yeast, plays a critical role in the APC and checkpoint pathway(s) (1996) (400)
- Polewards chromosome movement driven by microtubule depolymerization in vitro (1988) (398)
- Cse4p Is a Component of the Core Centromere of Saccharomyces cerevisiae (1998) (389)
- SMC2, a Saccharomyces cerevisiae gene essential for chromosome segregation and condensation, defines a subgroup within the SMC family. (1995) (356)
- Mitotic chromosome condensation. (1996) (345)
- Chromosome condensation and sister chromatid pairing in budding yeast (1994) (345)
- RNase H and multiple RNA biogenesis factors cooperate to prevent RNA:DNA hybrids from generating genome instability. (2011) (336)
- DNA Double-Strand Breaks Trigger Genome-Wide Sister-Chromatid Cohesion Through Eco1 (Ctf7) (2007) (327)
- Sister chromatid cohesion: a simple concept with a complex reality. (2008) (315)
- Role of astral microtubules and actin in spindle orientation and migration in the budding yeast, Saccharomyces cerevisiae (1992) (306)
- SMC1: an essential yeast gene encoding a putative head-rod-tail protein is required for nuclear division and defines a new ubiquitous protein family (1993) (301)
- Pds5p Is an Essential Chromosomal Protein Required for Both Sister Chromatid Cohesion and Condensation in Saccharomyces cerevisiae (2000) (293)
- Genetic analysis of the mitotic transmission of minichromosomes (1985) (290)
- Novel PI(4)P 5-kinase homologue, Fab1p, essential for normal vacuole function and morphology in yeast. (1995) (272)
- Secretion of beta-lactamase requires the carboxy end of the protein (1980) (263)
- Chromosomal Addresses of the Cohesin Component Mcd1p (2000) (244)
- Pds1p is required for faithful execution of anaphase in the yeast, Saccharomyces cerevisiae (1996) (219)
- Saccharomyces cerevisiae kinesin- and dynein-related proteins required for anaphase chromosome segregation (1995) (209)
- Single-Molecule Imaging Reveals a Collapsed Conformational State for DNA-Bound Cohesin. (2016) (201)
- The centromeric sister chromatid cohesion site directs Mcd1p binding to adjacent sequences. (1999) (195)
- In vivo dissection of the chromosome condensation machinery (2002) (194)
- Budding yeast centromere composition and assembly as revealed by in vivo cross-linking. (1997) (186)
- S1-DRIP-seq identifies high expression and polyA tracts as major contributors to R-loop formation (2016) (184)
- The anaphase inhibitor of Saccharomyces cerevisiae Pds1p is a target of the DNA damage checkpoint pathway. (1997) (183)
- Tardigrades Use Intrinsically Disordered Proteins to Survive Desiccation. (2017) (180)
- In vivo requirements for rDNA chromosome condensation reveal two cell-cycle-regulated pathways for mitotic chromosome folding. (2004) (173)
- The homologous recombination machinery modulates the formation of RNA–DNA hybrids and associated chromosome instability (2013) (169)
- The Kinetochore Is an Enhancer of Pericentric Cohesin Binding (2004) (153)
- Rings, bracelet or snaps: fashionable alternatives for Smc complexes (2005) (148)
- Addition of extra origins of replication to a minichromosome suppresses its mitotic loss in cdc6 and cdc14 mutants of Saccharomyces cerevisiae. (1992) (148)
- Trehalose Is a Versatile and Long-Lived Chaperone for Desiccation Tolerance (2014) (148)
- Systematic Reduction of Cohesin Differentially Affects Chromosome Segregation, Condensation, and DNA Repair (2010) (147)
- Distinct targets of the Eco1 acetyltransferase modulate cohesion in S phase and in response to DNA damage. (2009) (145)
- Mitotic chromosome condensation requires Brn1p, the yeast homologue of Barren. (2000) (145)
- The kleisin subunit of cohesin dictates damage-induced cohesion. (2008) (137)
- Evidence for posttranslational translocation of β-lactamase across the bacterial inner membrane (1982) (134)
- Pds1p of budding yeast has dual roles: inhibition of anaphase initiation and regulation of mitotic exit. (1999) (132)
- Ctf19p: A Novel Kinetochore Protein in Saccharomyces cerevisiae and a Potential Link between the Kinetochore and Mitotic Spindle (1999) (117)
- Increasing intracellular trehalose is sufficient to confer desiccation tolerance to Saccharomyces cerevisiae (2015) (117)
- Sister chromatid cohesion: the beginning of a long and beautiful relationship. (2000) (115)
- Chromosome Morphogenesis: Condensin-Dependent Cohesin Removal during Meiosis (2005) (113)
- The CDC20 gene product of Saccharomyces cerevisiae, a beta-transducin homolog, is required for a subset of microtubule-dependent cellular processes (1991) (108)
- Centromere position in budding yeast: evidence for anaphase A. (1997) (107)
- The structure of sister minichromosome DNA before anaphase in Saccharomyces cerevisiae. (1987) (105)
- RNase H enables efficient repair of R-loop induced DNA damage (2016) (101)
- Genome-wide Map of R-Loop-Induced Damage Reveals How a Subset of R-Loops Contributes to Genomic Instability. (2018) (101)
- Diverse effects of mutations in the signal sequence on the secretion of β-lactamase in Salmonella typhimurium (1982) (101)
- The Yin and Yang of R-loop biology. (2015) (98)
- Meiotic condensin is required for proper chromosome compaction, SC assembly, and resolution of recombination-dependent chromosome linkages (2003) (92)
- A genetic analysis of dicentric minichromosomes in saccharomyces cerevisiae (1987) (89)
- CEP3 encodes a centromere protein of Saccharomyces cerevisiae (1995) (86)
- The dynamics of chromosome movement in the budding yeast Saccharomyces cerevisiae (1989) (84)
- A functional assay for centromere-associated sister chromatid cohesion. (1999) (74)
- Chromosome integrity in Saccharomyces cerevisiae: the interplay of DNA replication initiation factors, elongation factors, and origins. (2003) (74)
- An evaluation of the relatedness of proteins based on comparison of amino acid sequences. (1970) (72)
- Faithful chromosome transmission requires Spt4p, a putative regulator of chromatin structure in Saccharomyces cerevisiae (1996) (72)
- Cohesin-independent segregation of sister chromatids in budding yeast (2012) (70)
- A Multi-Step Pathway for the Establishment of Sister Chromatid Cohesion (2006) (68)
- The ATPases of cohesin interface with regulators to modulate cohesin-mediated DNA tethering (2015) (67)
- The Aurora kinase Ipl1 maintains the centromeric localization of PP2A to protect cohesin during meiosis (2007) (65)
- Visual assay for chromosome ploidy. (1987) (64)
- Interallelic complementation provides functional evidence for cohesin–cohesin interactions on DNA (2015) (63)
- Competitive Repair by Naturally Dispersed Repetitive DNA during Non-Allelic Homologous Recombination (2010) (59)
- Mitotic transmission of artificial chromosomes in cdc mutants of the yeast, Saccharomyces cerevisiae. (1990) (59)
- Genetic Analysis of Desiccation Tolerance in Saccharomyces cerevisiae (2011) (57)
- The metaphase-to-anaphase transition: avoiding a mid-life crisis. (1997) (54)
- Analysis of chromosome segregation in Saccharomyces cerevisiae. (1991) (53)
- Centromere-dependent binding of yeast minichromosomes to microtubules in vitro (1991) (52)
- SMC Complexes--Wrapped Up in Controversy (2003) (51)
- Structure and function of chromosomes in mitosis of budding yeast. (1993) (51)
- ROCC, a conserved region in cohesin's Mcd1 subunit, is essential for the proper regulation of the maintenance of cohesion and establishment of condensation (2014) (48)
- A Conserved Domain in the Scc3 Subunit of Cohesin Mediates the Interaction with Both Mcd1 and the Cohesin Loader Complex (2015) (46)
- Segment-directed mutagenesis: construction in vitro of point mutations limited to a small predetermined region of a circular DNA molecule. (1980) (45)
- TOR and RAS pathways regulate desiccation tolerance in Saccharomyces cerevisiae (2013) (44)
- Mitosis: Back to the basics (1994) (42)
- Differential roles of the RNases H in preventing chromosome instability (2016) (40)
- Cohesin residency determines chromatin loop patterns (2020) (38)
- Genetic Evidence that the Acetylation of the Smc3p Subunit of Cohesin Modulates Its ATP-Bound State to Promote Cohesion Establishment in Saccharomyces cerevisiae (2010) (35)
- A novel mechanism for the establishment of sister chromatid cohesion by the ECO1 acetyltransferase (2015) (32)
- Pdslp Is Required for Faithful Execution of Anaphase in the Yeast (1996) (31)
- Molecular biology. SMC complexes--wrapped up in controversy. (2003) (30)
- Relation of protein subunit interactions to the molecular species observed during cooperative binding of ligands. (1967) (29)
- Role of flexibility in the specificity, control and evolution of enzymes (1976) (27)
- In vitro assembly of physiological cohesin/DNA complexes (2011) (26)
- Synergy between the small intrinsically disordered protein Hsp12 and trehalose sustain viability after severe desiccation (2018) (26)
- Cohesin Interaction with Centromeric Minichromosomes Shows a Multi-Complex Rod-Shaped Structure (2008) (22)
- Desiccation tolerance: an unusual window into stress biology (2019) (21)
- Intermediate step of cohesin’s ATPase cycle allows cohesin to entrap DNA (2018) (20)
- The zinc finger of Eco1 enhances its acetyltransferase activity during sister chromatid cohesion (2009) (20)
- Centromere function on minichromosomes isolated from budding yeast. (1993) (19)
- The Rs of biology: R-loops and the regulation of regulators. (2013) (18)
- Cohesin Function in Cohesion, Condensation, and DNA Repair Is Regulated by Wpl1p via a Common Mechanism in Saccharomyces cerevisiae (2017) (17)
- The effect of 2,3-diphosphoglyceric acid on the changes in - interactions in hemoglobin during oxygenation. (1971) (15)
- A simple colony‐formation assay in liquid medium, termed ‘tadpoling’, provides a sensitive measure of Saccharomyces cerevisiae culture viability (2013) (13)
- Cohesin architecture and clustering in vivo (2021) (12)
- A role for the Smc3 hinge domain in the maintenance of sister chromatid cohesion (2017) (12)
- The spatial regulation of condensin activity in chromosome condensation (2019) (10)
- Communication between distinct subunit interfaces of the cohesin complex promotes its topological entrapment of DNA (2019) (9)
- DNA Resection at Chromosome Breaks Promotes Genome Stability by Constraining Non-Allelic Homologous Recombination (2012) (9)
- Telomere behavior in a hybrid yeast (2009) (9)
- Back to the Future: Mutant Hunts Are Still the Way To Go (2016) (7)
- Unifying forces for chromosomes in mitosis (1992) (7)
- Mitotic chromosome transmission (1985) (6)
- A role for the Smc 3 hinge domain in the maintenance of sister chromatid 1 cohesion 2 3 (2017) (5)
- The zinc finger of Eco 1 enhances its acetyltransferase activity during sister chromatid cohesion (2009) (3)
- Author response: The ATPases of cohesin interface with regulators to modulate cohesin-mediated DNA tethering (2015) (3)
- Author response: RNase H enables efficient repair of R-loop induced DNA damage (2016) (2)
- Gelation and Vitrification of Tardigrade IDPs (2018) (2)
- Author response: The homologous recombination machinery modulates the formation of RNA–DNA hybrids and associated chromosome instability (2013) (1)
- A model for Scc2p stimulation of cohesin's ATPase and its inhibition by acetylation of Smc3p (2022) (1)
- Tardigrade Disordered Proteins Mediate Desiccation Tolerance (2017) (1)
- Evidence for beta--beta interactions during the binding of oxygen to hemoglobin. (1969) (0)
- Synergism between a simple sugar and a small intrinsically disordered protein mitigate the lethal stresses of severe water loss (2017) (0)
- A genetic analysis of the secretion of β-lactamase (1982) (0)
- Genes that control mitotic chromosome transmission (1985) (0)
- NEGATIVE COOPERA TIVITY IN REGULATORY ENZYMES* BY ALEXANDER LEVIT6KIt AND D. E. KOSHLAND, JR (0)
- Author response: Cohesin residency determines chromatin loop patterns (2020) (0)
- architecture and clustering in vivo. (2021) (0)
- Heredity, environment, and chance in the responses of an individual cell. (1978) (0)
- Author response: Cohesin architecture and clustering in vivo (2021) (0)
- The role of the Saccharomyces cerevisiae CDC16 gene product in chromosome segregation (1990) (0)
- Collisions with Proteins on DNA Reveal a Small Functional Pore Size in the Cohesin Complex (2016) (0)
- Cohesin in space and time: architecture and oligomerization in vivo (2020) (0)
- The 2021 Genetics Society of America Medal: Douglas Koshland (2022) (0)
- Budding yeast Wpl1p regulates cohesin functions in cohesion, condensation and DNA repair by a common mechanism (2017) (0)
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