Douglas A. Melton

Douglas A. Melton's AcademicInfluence.com Rankings

Douglas A. Melton

Law

#977

World Rank

#1268

Historical Rank

#532

USA Rank

Common Law

#24

World Rank

#27

Historical Rank

USA Rank

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Why Is Douglas A. Melton Influential?

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According to Wikipedia, Douglas A. Melton is an American medical researcher who is the Xander University Professor at Harvard University, and was an investigator at the Howard Hughes Medical Institute until 2022. Melton serves as the co-director of the Harvard Stem Cell Institute and was the first co-chairman of the Harvard University Department of Stem Cell and Regenerative Biology. Melton is the founder of several biotech companies including Gilead Sciences, Ontogeny , iPierian , and Semma Therapeutics. Melton holds membership in the National Academy of the Sciences, the American Academy of Arts and Sciences, and is a founding member of the International Society for Stem Cell Research.

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Douglas A. Melton's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Efficient in vitro synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter. (1984) (5230)
Core Transcriptional Regulatory Circuitry in Human Embryonic Stem Cells (2005) (4503)
Control of Developmental Regulators by Polycomb in Human Embryonic Stem Cells (2006) (2393)
A molecular mechanism for the effect of lithium on development. (1996) (2350)
In vivo reprogramming of adult pancreatic exocrine cells to β-cells (2008) (1928)
"Stemness": Transcriptional Profiling of Embryonic and Adult Stem Cells (2002) (1782)
Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds (2008) (1591)
Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors. (2002) (1562)
Generation of Functional Human Pancreatic β Cells In Vitro (2014) (1520)
Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2 (2008) (1378)
Functional messenger RNAs are produced by SP6 in vitro transcription of cloned cDNAs. (1984) (1324)
Adult pancreatic β-cells are formed by self-duplication rather than stem-cell differentiation (2004) (1299)
Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation. (2004) (1200)
Effects of eight growth factors on the differentiation of cells derived from human embryonic stem cells. (2000) (1155)
Induction of Pancreatic Differentiation by Signals from Blood Vessels (2001) (1055)
Derivation of embryonic stem-cell lines from human blastocysts. (2004) (973)
Nuclear Reprogramming of Somatic Cells After Fusion with Human Embryonic Stem Cells (2005) (950)
A Single-Cell Transcriptomic Map of the Human and Mouse Pancreas Reveals Inter- and Intra-cell Population Structure. (2016) (888)
Hedgehog signals regulate multiple aspects of gastrointestinal development. (2000) (833)
Notch signaling controls multiple steps of pancreatic differentiation (2003) (786)
Follistatin, an antagonist of activin, is expressed in the Spemann organizer and displays direct neuralizing activity (1994) (779)
A maternal mRNA localized to the vegetal hemisphere in xenopus eggs codes for a growth factor related to TGF-β (1987) (739)
Marked differences in differentiation propensity among human embryonic stem cell lines (2008) (659)
Notochord repression of endodermal Sonic hedgehog permits pancreas development. (1998) (643)
In vitro RNA synthesis with SP6 RNA polymerase. (1987) (633)
Activins are expressed early in Xenopus embryogenesis and can induce axial mesoderm and anterior structures (1990) (587)
A truncated activin receptor inhibits mesoderm induction and formation of axial structures in Xenopus embryos (1992) (570)
Generation of pluripotent stem cells from patients with type 1 diabetes (2009) (566)
Vertebrate endoderm development. (1999) (542)
Recovery from diabetes in mice by β cell regeneration (2007) (538)
A multipotent progenitor domain guides pancreatic organogenesis. (2007) (531)
Injected Wnt RNA induces a complete body axis in Xenopus embryos (1991) (526)
Insulin Staining of ES Cell Progeny from Insulin Uptake (2003) (520)
Inhibition of activin receptor signaling promotes neuralization in Xenopus (1994) (520)
Endothelial signaling during development (2003) (506)
The vascular basement membrane: a niche for insulin gene expression and Beta cell proliferation. (2006) (488)
Studies with a Xenopus BMP receptor suggest that ventral mesoderm-inducing signals override dorsal signals in vivo (1994) (488)
A small molecule that directs differentiation of human ESCs into the pancreatic lineage. (2009) (479)
Expression of Xenopus N-CAM RNA in ectoderm is an early response to neural induction. (1987) (471)
Xenopus Mad Proteins Transduce Distinct Subsets of Signals for the TGFβ Superfamily (1996) (462)
Long term Glycemic Control Using Polymer Encapsulated, Human Stem-Cell Derived β-cells in Immune Competent mice (2016) (441)
Processed Vg1 protein is an axial mesoderm inducer in xenopus (1993) (439)
Small molecules efficiently direct endodermal differentiation of mouse and human embryonic stem cells. (2009) (420)
Notochord to endoderm signaling is required for pancreas development. (1997) (418)
Regulation of pancreas development by hedgehog signaling. (2000) (415)
Identification and cloning of localized maternal RNAs from xenopus eggs (1985) (411)
A two-step model for the localization of maternal mRNA in Xenopus oocytes: involvement of microtubules and microfilaments in the translocation and anchoring of Vg1 mRNA. (1990) (402)
Recovery from diabetes in mice by beta cell regeneration. (2007) (390)
RETRACTED: Betatrophin: A Hormone that Controls Pancreatic β Cell Proliferation (2013) (382)
Role of VEGF-A in Vascularization of Pancreatic Islets (2003) (381)
Human β-globin pre-mRNA synthesized in vitro is accurately spliced in xenopus oocyte nuclei (1983) (379)
Organ size is limited by the number of embryonic progenitor cells in the pancreas but not the liver (2007) (379)
Early mouse endoderm is patterned by soluble factors from adjacent germ layers. (2000) (374)
Vertebrate Embryonic Cells Will Become Nerve Cells Unless Told Otherwise (1997) (365)
The mRNA encoding elongation factor 1-α (EF-1α) is a major transcript at the midblastula transition in Xenopus (1989) (347)
Translocation of a localized maternal mRNA to the vegetal pole of Xenopus oocytes (1987) (346)
Xwnt-11: a maternally expressed Xenopus wnt gene. (1993) (327)
Nuclear Reprogramming in Cells (2008) (322)
Injected anti-sense RNAs specifically block messenger RNA translation in vivo. (1985) (313)
Setting Standards for Human Embryonic Stem Cells (2003) (311)
Diffusible factors in vertebrate embryonic induction (1992) (310)
Functional beta-cell maturation is marked by an increased glucose threshold and by expression of urocortin 3 (2012) (308)
Pten constrains centroacinar cell expansion and malignant transformation in the pancreas. (2005) (299)
Key events of pancreas formation are triggered in gut endoderm by ectopic expression of pancreatic regulatory genes. (2001) (298)
Vertebrate embryonic induction: mesodermal and neural patterning. (1994) (297)
Direct regulation of intestinal fate by Notch. (2005) (296)
A gene regulatory network in mouse embryonic stem cells (2007) (288)
Sox17 promotes differentiation in mouse embryonic stem cells by directly regulating extraembryonic gene expression and indirectly antagonizing self-renewal. (2010) (286)
Generation of stem cell-derived β-cells from patients with type 1 diabetes (2016) (286)
Mesodermal patterning by an inducer gradient depends on secondary cell–cell communication (1994) (285)
Antisense RNA injections in fertilized frog eggs reveal an RNA duplex unwinding activity (1987) (281)
Vegetal messenger RNA localization directed by a 340-nt RNA sequence element in Xenopus oocytes. (1992) (278)
Notch signaling promotes airway mucous metaplasia and inhibits alveolar development (2009) (277)
Endoderm development: from patterning to organogenesis. (2000) (276)
Charting cellular identity during human in vitro β-cell differentiation (2019) (276)
Pancreas development is promoted by cyclopamine, a hedgehog signaling inhibitor. (1998) (272)
Interaction between peptide growth factors and homoeobox genes in the establishment of antero-posterior polarity in frog embryos (1989) (272)
Role of endothelial cells in early pancreas and liver development (2003) (268)
Turning straw into gold: directing cell fate for regenerative medicine (2011) (266)
Differentiated human stem cells resemble fetal, not adult, β cells (2014) (255)
Extreme makeover: converting one cell into another. (2008) (252)
β-Catenin is essential for pancreatic acinar but not islet development (2005) (249)
Global expression analysis of gene regulatory pathways during endocrine pancreatic development (2004) (247)
Artifactual insulin release from differentiated embryonic stem cells. (2004) (246)
Signals from lateral plate mesoderm instruct endoderm toward a pancreatic fate. (2003) (245)
All β Cells Contribute Equally to Islet Growth and Maintenance (2007) (245)
Single-cell transcript analysis of pancreas development. (2003) (241)
Genes, signals, and lineages in pancreas development. (2003) (235)
Direct lineage tracing reveals the ontogeny of pancreatic cell fates during mouse embryogenesis (2003) (234)
Specificity of antisense oligonucleotides in vivo. (1992) (227)
Mixer, a homeobox gene required for endoderm development. (1998) (223)
Pancreas regeneration (2018) (218)
Activin receptor patterning of foregut organogenesis. (2000) (216)
Activin can induce the formation of axial structures and is expressed in the hypoblast of the chick (1990) (215)
Involvement of p21ras in Xenopus mesoderm induction (1992) (212)
How to make a functional β-cell (2013) (203)
TGF-beta signals and a pattern in Xenopus laevis endodermal development. (1996) (199)
Pattern formation during animal development. (1991) (198)
Pre-existent pattern in Xenopus animal pole cells revealed by induction with activin (1991) (193)
Transcriptional dynamics of endodermal organ formation (2009) (189)
Nomenclature: Vertebrate Mediators of TGFβ Family Signals (1996) (189)
Mothers against dpp encodes a conserved cytoplasmic protein required in DPP/TGF-beta responsive cells. (1996) (181)
Involvement of the Xenopus homeobox gene Xhox3 in pattern formation along the anterior-posterior axis (1989) (180)
Order and intracellular location of the events involved in the maturation of a spliced tRNA (1980) (180)
Optimal timing of inner cell mass isolation increases the efficiency of human embryonic stem cell derivation and allows generation of sibling cell lines. (2009) (173)
Xnr4: a Xenopus nodal-related gene expressed in the Spemann organizer. (1997) (171)
Vertebrate neural induction. (1997) (168)
Identification of a novel transforming growth factor-beta (TGF-beta 5) mRNA in Xenopus laevis. (1990) (166)
Generation of hypoimmunogenic human pluripotent stem cells (2019) (162)
Identifying gene expression programs of cell-type identity and cellular activity with single-cell RNA-Seq (2018) (160)
Induction of dorsal mesoderm by soluble, mature Vg1 protein. (1995) (159)
Wnt7b stimulates embryonic lung growth by coordinately increasing the replication of epithelium and mesenchyme (2008) (156)
Gene transfer in amphibian eggs and oocytes. (1981) (153)
A simple tool to improve pluripotent stem cell differentiation (2013) (153)
Assays for gene function in developing Xenopus embryos. (1991) (152)
Bimodal and graded expression of the Xenopus homeobox gene Xhox3 during embryonic development. (1989) (148)
Developmental regulation of a gastrula‐specific gene injected into fertilized Xenopus eggs. (1985) (147)
The Src Family of Tyrosine Kinases Is Important for Embryonic Stem Cell Self-renewal* (2004) (145)
Mutant Vg1 ligands disrupt endoderm and mesoderm formation in Xenopus embryos. (1998) (143)
Notch gene expression during pancreatic organogenesis (2000) (140)
The maternal mRNA Vg1 is correctly localized following injection into Xenopus oocytes (1988) (140)
Synthesis of long, capped transcripts in vitro by SP6 and T7 RNA polymerases. (1989) (140)
The stability, toxicity and effectiveness of unmodified and phosphorothioate antisense oligodeoxynucleotides in Xenopus oocytes and embryos. (1990) (133)
Prospective isolation and global gene expression analysis of definitive and visceral endoderm. (2007) (132)
A mouse macrophage factor induces head structures and organizes a body axis in Xenopus. (1990) (132)
Adenosine kinase inhibition selectively promotes rodent and porcine islet β-cell replication (2012) (130)
Self-renewal of embryonic-stem-cell-derived progenitors by organ-matched mesenchyme (2012) (127)
Platelet-derived growth factor A chain is maternally encoded in Xenopus embryos. (1988) (125)
Localized synthesis of the Vg1 protein during early Xenopus development. (1989) (124)
Xfin: an embryonic gene encoding a multifingered protein in Xenopus. (1987) (120)
Analysis of pancreatic development in living transgenic zebrafish embryos (2001) (117)
In vivo reprogramming of pancreatic acinar cells to three islet endocrine subtypes (2014) (116)
Growth factors in early embryogenesis. (1989) (114)
Regenerating the field of cardiovascular cell therapy (2019) (114)
Short-Range Signaling by Candidate Morphogens of the TGFβ Family and Evidence for a Relay Mechanism of Induction (1996) (108)
Reprogrammed Stomach Tissue as a Renewable Source of Functional β Cells for Blood Glucose Regulation. (2016) (106)
Formation of the 3′ end of histone mRNA by post-transcriptional processing (1984) (104)
MARIS: Method for Analyzing RNA following Intracellular Sorting (2014) (104)
Embryonic expression and nuclear localization of Xenopus homeobox (Xhox) gene products. (1986) (103)
Retraction Notice to: Betatrophin: A Hormone that Controls Pancreatic β Cell Proliferation (2017) (103)
Microinjection of synthetic Xhox-1A homeobox mRNA disrupts somite formation in developing Xenopus embryos (1988) (102)
Wnt signaling specifies and patterns intestinal endoderm (2011) (101)
Expression of activin mRNA during early development in Xenopus laevis. (1993) (100)
Reversal of β cell de-differentiation by a small molecule inhibitor of the TGFβ pathway (2014) (97)
Pancreas specification: a budding question. (2003) (92)
YAP inhibition enhances the differentiation of functional stem cell-derived insulin-producing β cells (2019) (92)
Vertebrate Embryonic Cells Review Will Become Nerve Cells Unless Told Otherwise (1997) (91)
Circadian Entrainment Triggers Maturation of Human In Vitro Islets. (2019) (89)
Functional genomics of the endocrine pancreas: the pancreas clone set and PancChip, new resources for diabetes research. (2002) (88)
The mRNA encoding elongation factor 1-alpha (EF-1 alpha) is a major transcript at the midblastula transition in Xenopus. (1989) (88)
Handbook of stem cells (2013) (83)
The Xenopus localized messenger RNA An3 may encode an ATP-dependent RNA helicase (1991) (82)
Interaction of Wnt and activin in dorsal mesoderm induction in Xenopus. (1992) (82)
“Stemness”: Definitions, Criteria, and Standards (2004) (82)
Wnt Signaling Separates the Progenitor and Endocrine Compartments during Pancreas Development. (2019) (78)
A Peninsular Structure Coordinates Asynchronous Differentiation with Morphogenesis to Generate Pancreatic Islets (2019) (77)
An improved ScoreCard to assess the differentiation potential of human pluripotent stem cells (2015) (77)
Xenopus axis formation: induction of goosecoid by injected Xwnt-8 and activin mRNAs. (1993) (76)
Nomenclature: vertebrate mediators of TGFbeta family signals. (1996) (73)
Altered nuclear transfer in stem-cell research - a flawed proposal. (2004) (73)
Reprogramming within hours following nuclear transfer into mouse but not human zygotes. (2011) (72)
Alginate‐microencapsulation of human stem cell–derived β cells with CXCL12 prolongs their survival and function in immunocompetent mice without systemic immunosuppression (2019) (72)
Notch signaling reveals developmental plasticity of Pax4 + pancreatic endocrine progenitors and shunts them to a duct fate (2007) (71)
How to make beta cells? (2009) (71)
Correction: Corrigendum: Long-term glycemic control using polymer-encapsulated human stem cell–derived beta cells in immune-competent mice (2016) (70)
Development of the pancreas in Xenopus laevis (2000) (69)
Induction and patterning of the vertebrate nervous system. (1995) (68)
Induction of mesoderm in Xenopus laevis embryos by translation initiation factor 4E. (1994) (68)
Axial patterning and the establishment of polarity in the frog embryo. (1990) (67)
TGF-β signals and a prepattern in Xenopus laevis endodermal development (1996) (66)
Embryonic expression and functional analysis of a Xenopus activin receptor (1992) (64)
Facultative Endocrine Progenitor Cells in the Adult Pancreas (2008) (61)
A Nutrient-Sensing Transition at Birth Triggers Glucose-Responsive Insulin Secretion. (2020) (59)
Transcription of cloned tRNA genes and the nuclear partitioning of a tRNA precursor (1979) (59)
Induction of axial mesoderm by zDVR-1, the zebrafish orthologue of Xenopus Vg1. (1996) (58)
Pancreas development in the chick embryo. (1997) (58)
Genetic targeting of the endoderm with claudin-6CreER (2008) (57)
Promoter of a eukaryotic tRNAPro gene is composed of three noncontiguous regions. (1982) (57)
How Important are Adult Stem Cells for Tissue Maintenance? (2004) (56)
Report of the Key Opinion Leaders Meeting on Stem Cell-derived Beta Cells. (2018) (54)
Functional evaluation of ES cell-derived endodermal populations reveals differences between Nodal and Activin A-guided differentiation (2013) (52)
An enhancer responsible for activating transcription at the midblastula transition in Xenopus development. (1987) (52)
Synchronized stimulation and continuous insulin sensing in a microfluidic human Islet on a Chip designed for scalable manufacturing. (2019) (50)
Inhibition of mTOR Signaling Enhances Maturation of Cardiomyocytes Derived From Human-Induced Pluripotent Stem Cells via p53-Induced Quiescence (2019) (50)
Hormonal regulation of embryogenesis: the formation of mesoderm in Xenopus laevis. (1994) (50)
Cloning of nematode tRNA genes and their expression in the frog oocyte. (1978) (50)
A maternal mRNA localized to the animal pole of Xenopus eggs encodes a subunit of mitochondrial ATPase. (1987) (49)
Derivation of Human Embryonic Stem Cells (2007) (49)
Translation of messenger RNA in injected frog oocytes. (1987) (48)
Corrigendum: Long-term glycemic control using polymer-encapsulated human stem cell–derived beta cells in immune-competent mice (2016) (48)
The length of nucleosome-associated DNA is the same in both transcribed and nontranscribed regions of chromatin (1978) (47)
Resolving Discrepant Findings on ANGPTL8 in β-Cell Proliferation: A Collaborative Approach to Resolving the Betatrophin Controversy (2016) (46)
Pancreatic lineage analysis using a retroviral vector in embryonic mice demonstrates a common progenitor for endocrine and exocrine cells. (2002) (46)
Response to Comments on " 'Stemness': Transcriptional Profiling of Embryonic and Adult Stem Cells" and "A Stem Cell Molecular Signature" (2003) (46)
The promise of stem cell-derived islet replacement therapy (2021) (44)
Glucose Response by Stem Cell-Derived β Cells In Vitro Is Inhibited by a Bottleneck in Glycolysis (2020) (44)
Perspectives on the Activities of ANGPTL8/Betatrophin (2014) (42)
Correction: All ß Cells Contribute Equally to Islet Growth and Maintenance (2007) (41)
Modeling Type 1 Diabetes In Vitro Using Human Pluripotent Stem Cells (2020) (39)
Transcription of tRNA genes in vivo: single-stranded compared to double-stranded templates. (1980) (39)
A method for the generation of human stem cell-derived alpha cells (2020) (39)
Expression of the Xhox3 Homeobox Protein in Xenopus Embryos: Blocking Its Early Function Suggests the Requirement of Xhox3 for Normal Posterior Development (1991) (38)
Impracticality of egg donor recruitment in the absence of compensation. (2011) (38)
Localized maternal mRNAs in Xenopus laevis eggs. (1985) (38)
Induction of mesoderm by a viral oncogene in early Xenopus embryos. (1989) (38)
Blastemal progenitors modulate immune signaling during early limb regeneration (2019) (34)
Testing Pancreatic Islet Function at the Single Cell Level by Calcium Influx with Associated Marker Expression (2015) (33)
A Stem Cell Approach to Cure Type 1 Diabetes. (2020) (31)
Self-organizational capacity of distally transplanted limb regeneration blastemas in larval salamanders. (1977) (30)
Establishment of human pluripotent stem cell-derived pancreatic β-like cells in the mouse pancreas (2018) (30)
Genome scale in vivo CRISPR screen identifies RNLS as a target for beta cell protection in type 1 diabetes (2020) (29)
Angptl4 links α-cell proliferation following glucagon receptor inhibition with adipose tissue triglyceride metabolism (2015) (29)
Slow and steady is the key to β-cell replication (2008) (27)
Using stem cells to study and possibly treat type 1 diabetes (2011) (27)
A Src inhibitor regulates the cell cycle of human pluripotent stem cells and improves directed differentiation (2015) (26)
The status of elephants in northern Botswana (1985) (26)
The process of localizing a maternal messenger RNA in Xenopus oocytes. (1989) (25)
Blood parameters of the wild chacma baboon, Papio ursinus (1982) (21)
Midkine is a dual regulator of wound epidermis development and inflammation during the initiation of limb regeneration (2020) (20)
Cell maturation: Hallmarks, triggers, and manipulation (2022) (19)
Chapter 2 – ‘Stemness’: Definitions, Criteria, and Standards (2014) (19)
Applied Developmental Biology: Making Human Pancreatic Beta Cells for Diabetics. (2016) (19)
A transcriptionally active pseudogene in Xenopus laevis oocyte 5S DNA (1981) (18)
Chapter 23 In Situ Hyridization (1991) (17)
A rapid increase in acetylcholinesterase mRNA during ascidian embryogenesis as demonstrated by microinjection into Xenopus laevis oocytes. (1983) (17)
Site-directed mutagenesis of a tRNA gene: base alterations in the coding region affect transcription. (1982) (17)
Reversal of type 1 diabetes in mice. (2006) (17)
A 3D culture platform enables development of zinc-binding prodrugs for targeted proliferation of β cells (2020) (16)
Pathways to new beta cells. (2008) (15)
A molecular mechanism for the effect of lithium on development (2019) (15)
Brief Report: VGLL4 Is a Novel Regulator of Survival in Human Embryonic Stem Cells (2013) (15)
Pathways to New β Cells (2008) (14)
New findings in pancreatic and intestinal endocrine development to advance regenerative medicine (2013) (14)
A therapeutic convection–enhanced macroencapsulation device for enhancing β cell viability and insulin secretion (2021) (14)
Exogenous GDF11, but not GDF8, reduces body weight and improves glucose homeostasis in mice (2020) (14)
Derivation of human embryonic stem cells by immunosurgery. (2007) (14)
Identification of a LIF-Responsive, Replication-Competent Subpopulation of Human β Cells. (2020) (13)
Sequences of four tRNA genes from Caenorhabditis elegans and the expression of C. elegans tRNALeu (anticodon IAG) in Xenopus oocytes. (1982) (13)
Derivation of human embryonic stem cell lines (2007) (13)
Screening for novel pancreatic genes expressed during embryogenesis. (1999) (12)
Antisense RNA and DNA (1988) (12)
Human embryonic stem cells. (2006) (11)
Modeling Human Nutrition Using Human Embryonic Stem Cells (2015) (10)
Genetic manipulation of stress pathways can protect stem-cell-derived islets from apoptosis in vitro (2022) (10)
Live Cell Monitoring and Enrichment of Stem Cell‐Derived β Cells Using Intracellular Zinc Content as a Population Marker (2019) (10)
Corrigendum: Generation of stem cell-derived β-cells from patients with type 1 diabetes (2016) (9)
Localization of mRNA and axis formation during Xenopus embryogenesis. (1989) (9)
Covalent Adduct Formation between the Antihypertensive Drug Hydralazine and Abasic Sites in Double- and Single-Stranded DNA (2014) (9)
The Molecular Biography of the Cell (2005) (9)
Whole-genome CRISPR screening identifies genetic manipulations to reduce immune rejection of stem cell-derived islets (2022) (8)
In Situ Hybridisation: Application to Developmental Biology and Medicine: The use of in situ hybridisation to study the localisation of maternal mRNAs during Xenopus oogenesis (1990) (7)
Translational control of activin in Xenopus laevis embryos. (1995) (7)
Supplemental Data Core Transcriptional Regulatory Circuitry in Human Embryonic Stem Cells (2005) (6)
Anti-sense RNA injections in fertilized eggs as a test for the function of localized mRNAs. (1986) (6)
Synthesis of Hybridization Probes and RNA Substrates with SP6 RNA Polymerase (1985) (6)
Apolipoprotein E is a pancreatic extracellular factor that maintains mature β-cell gene expression (2018) (6)
Building Biomimetic Potency Tests for Islet Transplantation (2021) (6)
A Multipotent Progenitor Domain Guides Pancreatic (6)
The role of short-range and long-range signaling in mesoderm induction and patterning duringXenopusdevelopment (1996) (6)
Notch signaling controls multiple steps of pancreatic (2003) (5)
Aspects of the blood chemistry of wild lions, Panthera leo (1987) (5)
Generation of a heterozygous GAPDH-Luciferase human ESC line (HVRDe008-A-1) for in vivo monitoring of stem cells and their differentiated progeny. (2021) (5)
Baboon (Papio ursinus) capture using a blow-dart system (1980) (4)
Genetics in an oocyte. (1979) (4)
Mentorship in Science: Response to AlShebli et al., Nature Communications 2020 (2021) (4)
Signals for tissue induction and organ formation in vertebrate embryos. (1997) (4)
Author response: Identifying gene expression programs of cell-type identity and cellular activity with single-cell RNA-Seq (2019) (3)
Essentials of Stem Cell Biology (Hardcover) (2005) (3)
Author Correction: Pancreas regeneration (2018) (3)
Development of the endocrine pancreas (2011) (3)
A human ESC line for efficient CRISPR editing of pluripotent stem cells. (2021) (3)
Purification of Live Stem-Cell-Derived Islet Lineage Intermediates. (2020) (2)
Transcription and Processing of Nematode tRNA Genes Microinjected into the Frog Oocyte (1980) (2)
Secreted cytokines provide local immune tolerance for human stem cell-derived islets (2022) (2)
Gene expression pattern Notch gene expression during pancreatic organogenesis (2000) (2)
In situ hyridization. (1991) (2)
Engineering human stem cell-derived islets to evade immune rejection and promote localized immune tolerance (2022) (2)
Part A: Directed Differentiation of Human Embryonic Stem Cells into Early Endoderm Cells (2007) (2)
Spatial Distribution, Cams Radiocarbon Geochronology, and Taxonomy of Fossil Bison in Montana: An Initial Appraisal (1999) (2)
Advancing Progress in Stem Cells and Biomedicine: 2018–2019 Year in Review (2019) (2)
Report Review: Archaeological Investigations In the Avon Valley By Lewis Kyle Napton (1983) (1)
Small‐molecule modulators of Nkx6.1 expression in pancreatic progenitor cells during directed differentiation of human embryonic stem cell to insulin producing beta cells (2013) (1)
Gene injection into amphibian oocytes. (1980) (1)
CHAPTER 6 – INDUCTIVE PHENOMENA (2000) (1)
A Detailed Plan for Getting Americans Back to Work (2020) (1)
Dissecting mechanisms of human islet differentiation and maturation through epigenome profiling (2019) (1)
The diet of bushpigs in a sugarcane agro-ecosystem. (1989) (1)
Variation in the artifact assemblages from five Oxbow sites (1988) (1)
A protocol to improve pluripotent stem cell differentiation (2013) (1)
Matters arising: Insufficient evidence that pancreatic β cells are derived from adult ductal Neurog3-expressing progenitors. (2023) (1)
Stem Cells in Translation (2013) (1)
Injected antisense RNAs specifically block messenger RNA translation in vivo ( hybrid arrested translation / embryogenesis / gene function ) (1)
BMP-12, BMP-13 and seneinducerende compositions thus (1994) (0)
Toward Improving Immunotolerance for Stem Cell-Derived Islets (2022) (0)
A Report of Two Areas in Phillips County, Montana Surveyed for the American Colloid Company (1980) (0)
Charting cellular identity during human in vitro β-cell differentiation (2019) (0)
46 – Pancreatic Stem Cells (2004) (0)
Archaeological Reconnaissance of the Nevada Creek Drainage (1984) (0)
Mp-52 use of (2006) (0)
331-LB: A Switch in Nutrient Sensing Controls Functional Maturation of Pancreatic Beta Cells (2019) (0)
In situ hydridization : Embryos (1991) (0)
A transgenic mouse system for conditional ablation and regeneration of pancreatic beta cells (2005) (0)
Author response: Midkine is a dual regulator of wound epidermis development and inflammation during the initiation of limb regeneration (2019) (0)
Other Future Directions (2010) (0)
Base metal mineralization in South Central Missouri. (1978) (0)
209.2: Engineering Immune-evasive Human Stem Cell-derived Islet Cells (2021) (0)
A method for the generation of human stem cell-derived alpha cells (2020) (0)
Developmental Cell Multipotent Progenitor Domain of the Pancreas of the pancreas ? (0)
Isolated DNA sequences encoding BMP-12 or BMP-13 protein that induce tendon / ligament-like tissue formation and their applications (1996) (0)
Data ‘ Stemness ’ : Transcriptional Profiling of Embryonic and Adult Stem Cells (0)
Protein Labelling Using Alkyne– Azide Methodology Quantifying the Polar Wind (0)
Chapter 35 – Pancreatic Stem Cells (2009) (0)
Analysis of gene expression profiles in preimplantation stage embryos by DNA microarrays (2003) (0)
Molecular approaches to early amphibian development (1988) (0)
Animal development from egg to embryo: Induction and axial patterning in vertebrate embryogenesis (1990) (0)
402.4: Genetic Approaches to Attain Hypo-immunogenic Human Stem Cell Derived Islets for Transplantation (2021) (0)
SC-β cells and compositions and methods for producing the cells (2014) (0)
Author Correction: Pancreas regeneration (2018) (0)
Whole Genome CRISPR Screening of Stem Cell Derived Islets Reveals Gene Targets for Hypo-Immunogenicity (2022) (0)
507 VALUE ASSESSMENT FOR PATIENTS WHO UNDERWENT MINIMALLY INVASIVE VS OPEN COLECTOMIES AT A TERTIARY MEDICAL CENTER (2020) (0)
The suit was filed against (2019) (0)
Thomson, et al. v. Thompson, et al. (2001) [1] (2018) (0)
Pancreas regeneration (2018) (0)
CRISPR and the Ethics of Germline Editing (2020) (0)
Exogenous GDF11, but not GDF8, reduces body weight and improves glucose homeostasis in mice (2020) (0)
Up-regulation of transcriptional factor E2F-1 in mammalian embryos: a lesson from gene expression profiles by DNA microarray (2004) (0)
Around the world in a month (2015) (0)
We hope you enjoy this day of scientific exchange and interaction and we look forward to our work together. (2009) (0)
Gene Transfer in Xenopus Eggs and Oocytes (1981) (0)
New Approaches, New Opportunities at the 2019 ISSCR Annual Meeting (2018) (0)
Signal transduction during mesoderm induction in Xenopus. (1990) (0)
COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY VOLUME LXXIII (2009) (0)
Organoid Maturation by Circadian Entrainment (2020) (0)
Prehistory of the Lolo and Bitterroot National Forests: (an Overview) or Making It in a Marginal Environment the Past 10,000 Years (1986) (0)
Comparison of global gene expression profiles between embryos cultured in vitro and obtained in vivo using DNA microarrays (2004) (0)
YAP inhibition enhances the differentiation of functional stem cell-derived insulin-producing β cells (2019) (0)
Regenerating the field of cardiovascular cell therapy (2019) (0)
Method of inducing and preserving neuronal cells (1994) (0)
BPM-12, BMP-13, as well as the tendon-inducing compositions (1996) (0)
Chapter 68 – Pancreatic Stem Cells (2013) (0)
Stem Cells Can Treat and Cure Diabetes (2015) (0)
209.6: Long-term Functional Survival of Human Stem Cell-derived Islets Microencapsulated in Alginate With CXCL12 in Non-human Primates Without Immunosuppression. (2021) (0)
Essay The Molecular Biography of the Cell (2005) (0)
Wnt Signaling Separates t he Progenitor and Endocrine Compartments during Pancreas Development Graphical (2019) (0)
Pdgf a chain is expressed in early mouse embryos and is maternally encoded in xenopus embryos (1989) (0)

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