Douglas W. Losordo

Douglas W. Losordo's AcademicInfluence.com Rankings

Douglas W. Losordo

Medical

#2305

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#2720

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Cardiology

#208

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#213

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Pharmacology

#237

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#277

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medical Degrees

Douglas W. Losordo

Philosophy

#6712

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#9799

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#3837

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#5056

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Medical
Philosophy

Douglas W. Losordo's Degrees

Doctorate Medicine University of Illinois College of Medicine
PhD Pharmacology University of Illinois College of Medicine

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Douglas W. Losordo's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Stromal Cell–Derived Factor-1 Effects on Ex Vivo Expanded Endothelial Progenitor Cell Recruitment for Ischemic Neovascularization (2003) (1208)
Gene therapy for myocardial angiogenesis: initial clinical results with direct myocardial injection of phVEGF165 as sole therapy for myocardial ischemia. (1998) (1022)
Statin Therapy Accelerates Reendothelialization: A Novel Effect Involving Mobilization and Incorporation of Bone Marrow-Derived Endothelial Progenitor Cells (2002) (998)
Intramyocardial Transplantation of Autologous Endothelial Progenitor Cells for Therapeutic Neovascularization of Myocardial Ischemia (2003) (691)
Inflammation-induced lymphangiogenesis in the cornea arises from CD11b-positive macrophages. (2005) (677)
Clonally expanded novel multipotent stem cells from human bone marrow regenerate myocardium after myocardial infarction. (2005) (593)
Intramyocardial Transplantation of Autologous CD34+ Stem Cells for Intractable Angina: A Phase I/IIa Double-Blind, Randomized Controlled Trial (2007) (554)
Exosomes From Human CD34+ Stem Cells Mediate Their Proangiogenic Paracrine Activity (2011) (533)
Variable expression of the estrogen receptor in normal and atherosclerotic coronary arteries of premenopausal women. (1994) (527)
Critical Reevaluation of Endothelial Progenitor Cell Phenotypes for Therapeutic and Diagnostic Use (2012) (494)
Phase 1/2 Placebo-Controlled, Double-Blind, Dose-Escalating Trial of Myocardial Vascular Endothelial Growth Factor 2 Gene Transfer by Catheter Delivery in Patients With Chronic Myocardial Ischemia (2002) (463)
Decreased macrophage number and activation lead to reduced lymphatic vessel formation and contribute to impaired diabetic wound healing. (2007) (450)
Estrogen-Mediated, Endothelial Nitric Oxide Synthase–Dependent Mobilization of Bone Marrow–Derived Endothelial Progenitor Cells Contributes to Reendothelialization After Arterial Injury (2003) (439)
Nitric oxide and angiogenesis. (2002) (403)
Therapeutic angiogenesis and vasculogenesis for ischemic disease: part II: cell-based therapies. (2004) (394)
Exosomes and cardiac repair after myocardial infarction. (2014) (388)
Hypoxic Preconditioning Enhances the Benefit of Cardiac Progenitor Cell Therapy for Treatment of Myocardial Infarction by Inducing CXCR4 Expression (2009) (371)
Therapeutic angiogenesis and vasculogenesis for ischemic disease. Part I: angiogenic cytokines. (2004) (367)
Acetylcysteine to prevent angiography-related renal tissue injury (the APART trial). (2002) (367)
Intramyocardial, Autologous CD34+ Cell Therapy for Refractory Angina (2011) (362)
Src blockade stabilizes a Flk/cadherin complex, reducing edema and tissue injury following myocardial infarction. (2004) (354)
CD34-Positive Cells Exhibit Increased Potency and Safety for Therapeutic Neovascularization After Myocardial Infarction Compared With Total Mononuclear Cells (2006) (345)
Gene therapy with vascular endothelial growth factor for inoperable coronary artery disease. (1999) (344)
Netrins Promote Developmental and Therapeutic Angiogenesis (2006) (332)
IL-10 Inhibits Inflammation and Attenuates Left Ventricular Remodeling After Myocardial Infarction via Activation of STAT3 and Suppression of HuR (2009) (331)
Role of endothelial nitric oxide synthase in endothelial cell migration. (1999) (327)
Left Ventricular Electromechanical Mapping to Assess Efficacy of phVEGF165 Gene Transfer for Therapeutic Angiogenesis in Chronic Myocardial Ischemia (2000) (325)
Unexpected Severe Calcification After Transplantation of Bone Marrow Cells in Acute Myocardial Infarction (2004) (322)
Estrogen and Angiogenesis: A Review (2001) (317)
Constitutive Human Telomerase Reverse Transcriptase Expression Enhances Regenerative Properties of Endothelial Progenitor Cells (2002) (313)
Sonic hedgehog myocardial gene therapy: tissue repair through transient reconstitution of embryonic signaling (2005) (310)
Estrogen-receptor-mediated inhibition of human endothelial cell apoptosis. Estradiol as a survival factor. (1997) (303)
Progressive Attenuation of Myocardial Vascular Endothelial Growth Factor Expression Is a Seminal Event in Diabetic Cardiomyopathy: Restoration of Microvascular Homeostasis and Recovery of Cardiac Function in Diabetic Cardiomyopathy After Replenishment of Local Vascular Endothelial Growth Factor (2005) (301)
Determination of bone marrow-derived endothelial progenitor cell significance in angiogenic growth factor-induced neovascularization in vivo. (2002) (297)
Histopathology of in-stent restenosis in patients with peripheral artery disease. (1997) (284)
Randomized, Single-Blind, Placebo-Controlled Pilot Study of Catheter-Based Myocardial Gene Transfer for Therapeutic Angiogenesis Using Left Ventricular Electromechanical Mapping in Patients With Chronic Myocardial Ischemia (2001) (275)
Supramolecular nanostructures that mimic VEGF as a strategy for ischemic tissue repair (2011) (275)
Endothelial progenitor cells in neovascularization of infarcted myocardium. (2008) (274)
Endothelial Progenitor Cells Are Rapidly Recruited to Myocardium and Mediate Protective Effect of Ischemic Preconditioning via “Imported” Nitric Oxide Synthase Activity (2005) (262)
Human studies of angiogenic gene therapy. (2009) (261)
Development of bioactive peptide amphiphiles for therapeutic cell delivery. (2010) (254)
Estradiol accelerates functional endothelial recovery after arterial injury. (1997) (249)
VEGF-C gene therapy augments postnatal lymphangiogenesis and ameliorates secondary lymphedema. (2003) (248)
Stem and progenitor cell-based therapy in ischaemic heart disease: promise, uncertainties, and challenges. (2011) (246)
Focal compensatory enlargement of human arteries in response to progressive atherosclerosis. In vivo documentation using intravascular ultrasound. (1994) (243)
Topical Sonic Hedgehog Gene Therapy Accelerates Wound Healing in Diabetes by Enhancing Endothelial Progenitor Cell–Mediated Microvascular Remodeling (2006) (236)
Vascular endothelial growth factor inhibits endothelial cell apoptosis induced by tumor necrosis factor-alpha: balance between growth and death signals. (1997) (229)
Local Gene Transfer of phVEGF-2 Plasmid by Gene-Eluting Stents: An Alternative Strategy for Inhibition of Restenosis (2004) (218)
Three-Dimensional Reconstruction of Human Coronary and Peripheral Arteries From Images Recorded During Two-Dimensional Intravascular Ultrasound Examination (1991) (218)
Estradiol Enhances Recovery After Myocardial Infarction by Augmenting Incorporation of Bone Marrow–Derived Endothelial Progenitor Cells Into Sites of Ischemia-Induced Neovascularization via Endothelial Nitric Oxide Synthase–Mediated Activation of Matrix Metalloproteinase-9 (2006) (212)
Postnatal Recapitulation of Embryonic Hedgehog Pathway in Response to Skeletal Muscle Ischemia (2003) (212)
Intracoronary administration of recombinant human vascular endothelial growth factor to patients with coronary artery disease. (2001) (210)
CXCR4 blockade augments bone marrow progenitor cell recruitment to the neovasculature and reduces mortality after myocardial infarction (2010) (210)
Vascular endothelial growth factor/vascular permeability factor (VEGF/VPF) in normal and atherosclerotic human arteries. (1997) (207)
Critical Role of Endothelial Notch1 Signaling in Postnatal Angiogenesis (2007) (207)
Endothelial Progenitor Thrombospondin-1 Mediates Diabetes-Induced Delay in Reendothelialization Following Arterial Injury (2006) (198)
Cell therapy of peripheral arterial disease: from experimental findings to clinical trials. (2013) (195)
Angiogenic Mechanisms of Human CD34+ Stem Cell Exosomes in the Repair of Ischemic Hindlimb (2017) (183)
Modulating the vascular response to limb ischemia: angiogenic and cell therapies. (2015) (172)
Sonic Hedgehog–Modified Human CD34+ Cells Preserve Cardiac Function After Acute Myocardial Infarction (2012) (165)
A Randomized, Controlled Pilot Study of Autologous CD34+ Cell Therapy for Critical Limb Ischemia (2012) (165)
How Does Angioplasy Work?: Serial Analysis of Human Iliac Arteries Using Intravascular Ultrasound (1992) (159)
IL‐10‐induced TNF‐alpha mRNA destabilization is mediated via IL‐10 suppression of p38 MAP kinase activation and inhibition of HuR expression (2006) (158)
Assessment of risks associated with cardiovascular gene therapy in human subjects. (2001) (150)
Estrogen Receptors &agr; and &bgr; Mediate Contribution of Bone Marrow–Derived Endothelial Progenitor Cells to Functional Recovery After Myocardial Infarction (2006) (145)
CD34-positive stem cells: in the treatment of heart and vascular disease in human beings. (2011) (140)
Sonic hedgehog regulates angiogenesis and myogenesis during post‐natal skeletal muscle regeneration (2009) (137)
Therapeutic angiogenesis for critical limb ischemia: microvascular therapies coming of age. (2008) (135)
Interleukin-10 Deficiency Impairs Bone Marrow–Derived Endothelial Progenitor Cell Survival and Function in Ischemic Myocardium (2011) (133)
An Open-Label Dose Escalation Study to Evaluate the Safety of Administration of Nonviral Stromal Cell-Derived Factor-1 Plasmid to Treat Symptomatic Ischemic Heart Failure (2013) (128)
Therapeutic angiogenesis for heart failure (1999) (127)
Sonic hedgehog induces angiogenesis via Rho kinase-dependent signaling in endothelial cells. (2010) (121)
One-year follow-up of direct myocardial gene transfer of vascular endothelial growth factor-2 using naked plasmid deoxyribonucleic acid by way of thoracotomy in no-option patients. (2003) (120)
Percutaneous intravascular US as adjunct to catheter-based interventions: preliminary experience in patients with peripheral vascular disease. (1990) (120)
Statins and the endothelium. (2007) (118)
Functional disruption of α4 integrin mobilizes bone marrow–derived endothelial progenitors and augments ischemic neovascularization (2006) (118)
A multicenter, randomized study of argatroban versus heparin as adjunct to tissue plasminogen activator (TPA) in acute myocardial infarction: myocardial infarction with novastan and TPA (MINT) study. (1999) (117)
Transplantation of endothelial progenitor cells for therapeutic neovascularization. (2002) (116)
Endothelial progenitor cells for cardiovascular regeneration. (2008) (116)
Global position paper on cardiovascular regenerative medicine (2017) (115)
Rebuilding the damaged heart: the potential of cytokines and growth factors in the treatment of ischemic heart disease. (2010) (114)
Combination Balloon‐Ultrasound Imaging Catheter for Percutaneous Transluminal Angioplasty: Validation of Imaging, Analysis of Recoil, and Identification of Plaque Fracture (1991) (113)
Sonic Hedgehog Induces Arteriogenesis in Diabetic Vasa Nervorum and Restores Function in Diabetic Neuropathy (2004) (112)
Gene therapy for myocardial angiogenesis. (1999) (111)
Cell cycle regulator E2F1 modulates angiogenesis via p53-dependent transcriptional control of VEGF. (2006) (110)
Synergistic Effect of Bone Marrow Mobilization and Vascular Endothelial Growth Factor-2 Gene Therapy in Myocardial Ischemia (2004) (110)
Catheter-based myocardial gene transfer utilizing nonfluoroscopic electromechanical left ventricular mapping. (1999) (110)
Neuronal Nitric Oxide Synthase Mediates Statin-Induced Restoration of Vasa Nervorum and Reversal of Diabetic Neuropathy (2005) (105)
Vascular endothelial growth factor gene transfer for diabetic polyneuropathy: A randomized, double‐blinded trial (2009) (101)
Atherosclerosis 2005: recent discoveries and novel hypotheses. (2005) (101)
The RENEW Trial: Efficacy and Safety of Intramyocardial Autologous CD34(+) Cell Administration in Patients With Refractory Angina. (2016) (100)
Role of endothelial progenitor cells during ischemia-induced vasculogenesis and collateral formation. (2010) (100)
Use of the Rabbit Ear Artery to Serially Assess Foreign Protein Secretion After Site‐Specific Arterial Gene Transfer In Vivo: Evidence That Anatomic Identification of Successful Gene Transfer May Underestimate the Potential Magnitude of Transgene Expression (1994) (97)
Tumor Necrosis Factor-α Receptor p75 Is Required in Ischemia-Induced Neovascularization (2007) (96)
The relative potency and safety of endothelial progenitor cells and unselected mononuclear cells for recovery from myocardial infarction and ischemia (2009) (92)
Endothelial recovery: the next target in restenosis prevention. (2003) (91)
The Neuropeptide Secretoneurin Acts as a Direct Angiogenic Cytokine In Vitro and In Vivo (2004) (88)
Forkhead box transcription factor FoxC1 preserves corneal transparency by regulating vascular growth (2011) (88)
Enhanced Angiogenic and Cardiomyocyte Differentiation Capacity of Epigenetically Reprogrammed Mouse and Human Endothelial Progenitor Cells Augments Their Efficacy for Ischemic Myocardial Repair (2012) (88)
CXCR4 Antagonist AMD3100 Accelerates Impaired Wound Healing in Diabetic Mice (2011) (86)
Estrogen receptors alpha and beta mediate contribution of bone marrow-derived endothelial progenitor cells to functional recovery after myocardial infarction. (2006) (85)
Comparative analysis of the in vivo angiogenic properties of stable prostacyclin analogs: a possible role for peroxisome proliferator-activated receptors. (2004) (84)
A phase 3, randomized, double-blinded, active-controlled, unblinded standard of care study assessing the efficacy and safety of intramyocardial autologous CD34+ cell administration in patients with refractory angina: design of the RENEW study. (2013) (84)
Long-term (2-year) clinical events following transthoracic intramyocardial gene transfer of VEGF-2 in no-option patients. (2005) (80)
CXC-Chemokine Receptor 4 Antagonist AMD3100 Promotes Cardiac Functional Recovery After Ischemia/Reperfusion Injury via Endothelial Nitric Oxide Synthase–Dependent Mechanism (2012) (78)
A critical role of Src family kinase in SDF-1/CXCR4-mediated bone-marrow progenitor cell recruitment to the ischemic heart. (2015) (78)
Therapeutic angiogenesis inhibits or rescues chemotherapy-induced peripheral neuropathy: taxol- and thalidomide-induced injury of vasa nervorum is ameliorated by VEGF. (2007) (77)
NF-kappaB balances vascular regression and angiogenesis via chromatin remodeling and NFAT displacement. (2010) (77)
PreSERVE-AMI: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial of Intracoronary Administration of Autologous CD34+ Cells in Patients With Left Ventricular Dysfunction Post STEMI. (2014) (77)
Cell-Free Embryonic Stem Cell Extract–Mediated Derivation of Multipotent Stem Cells From NIH3T3 Fibroblasts for Functional and Anatomical Ischemic Tissue Repair (2008) (77)
The cytoskeletal protein ezrin regulates EC proliferation and angiogenesis via TNF-alpha-induced transcriptional repression of cyclin A. (2005) (75)
STAT3-Dependent Mouse Embryonic Stem Cell Differentiation Into Cardiomyocytes: Analysis of Molecular Signaling and Therapeutic Efficacy of Cardiomyocyte Precommitted mES Transplantation in a Mouse Model of Myocardial Infarction (2007) (74)
Myocardial knockdown of mRNA‐stabilizing protein HuR attenuates post‐MI inflammatory response and left ventricular dysfunction in IL‐10‐null mice (2010) (71)
Autologous CD34+ cell therapy improves exercise capacity, angina frequency and reduces mortality in no-option refractory angina: a patient-level pooled analysis of randomized double-blinded trials (2018) (71)
Hypoxia up‐regulates the angiogenic cytokine secretoneurin via an HIF‐1α‐ and basic FGF‐dependent pathway in muscle cells (2007) (70)
Age-dependent VEGF expression and intraneural neovascularization during regeneration of peripheral nerves (2004) (70)
Liposome-mediated gene transfer into human vascular smooth muscle cells. (1994) (70)
Secretoneurin, an Angiogenic Neuropeptide, Induces Postnatal Vasculogenesis (2004) (70)
Transcutaneous ultrasound augments naked DNA transfection of skeletal muscle. (2002) (70)
Antiangiogenesis Mediates Cisplatin-Induced Peripheral Neuropathy: Attenuation or Reversal by Local Vascular Endothelial Growth Factor Gene Therapy Without Augmenting Tumor Growth (2005) (70)
Divergence of Angiogenic and Vascular Permeability Signaling by VEGF: Inhibition of Protein Kinase C Suppresses VEGF-Induced Angiogenesis, but Promotes VEGF-Induced, NO-Dependent Vascular Permeability (2002) (69)
Synergistic effect of combined intramyocardial CD34+ cells and VEGF2 gene therapy after MI (2006) (69)
Endothelial progenitor cells in regenerative medicine and cancer: a decade of research. (2008) (69)
On the fabric of the human body. (2012) (68)
Cell therapy for acute myocardial infarction: curb your enthusiasm? (2006) (65)
Negative Regulation of miR‐375 by Interleukin‐10 Enhances Bone Marrow‐Derived Progenitor Cell‐Mediated Myocardial Repair and Function After Myocardial Infarction (2015) (64)
Therapeutic myocardial angiogenesis with vascular endothelial growth factors (2004) (63)
Implications of the mechanical (PCI) vs thrombolytic controversy for ST segment elevation myocardial infarction on the organization of emergency medical services: the Boston EMS experience. (2004) (63)
CXCR4-Mediated Bone Marrow Progenitor Cell Maintenance and Mobilization Are Modulated by c-kit Activity (2010) (62)
Gene Therapy with Vascular Endothelial Growth Factor for Inoperable Coronary Artery Disease: Anesthetic Management and Results (2001) (62)
Tumor necrosis factor-alpha receptor p75 is required in ischemia-induced neovascularization. (2007) (61)
Non-viral vectors for gene therapy: clinical trials in cardiovascular disease. (2005) (61)
Therapeutic myocardial angiogenesis. (2007) (58)
The Hedgehog Transcription Factor Gli3 Modulates Angiogenesis (2009) (58)
Results of intracoronary recombinant human vascular endothelial growth factor (rhVEGF) administration trial (1998) (57)
In Vivo Blockade of Tumor Necrosis Factor-&agr; Accelerates Functional Endothelial Recovery After Balloon Angioplasty (2001) (56)
Functional Ephrin-B2 Expression for Promotive Interaction Between Arterial and Venous Vessels in Postnatal Neovascularization (2005) (54)
Sonic hedgehog-induced functional recovery after myocardial infarction is enhanced by AMD3100-mediated progenitor-cell mobilization. (2011) (52)
Notch Signaling Regulates Endothelial Progenitor Cell Activity During Recovery From Arterial Injury in Hypercholesterolemic Mice (2010) (51)
Restoration of E2F expression rescues vascular endothelial cells from tumor necrosis factor-alpha-induced apoptosis. (1998) (47)
Time course of recombinant protein secretion after liposome-mediated gene transfer in a rabbit arterial organ culture model. (1994) (47)
Pleiotropic beneficial effects of sonic hedgehog gene therapy in an experimental model of peripheral limb ischemia. (2011) (47)
Autologous CD34+ Cell Therapy for Refractory Angina: 2-Year Outcomes from the ACT34-CMI Study (2016) (46)
Oncogenic ras induces premature senescence in endothelial cells: role of p21Cip1/Waf1 (2002) (45)
Phase II clinical trial of CD34+ cell therapy to explore endpoint selection and timing in patients with critical limb ischemia. (2014) (45)
Topical application of ex vivo expanded endothelial progenitor cells promotes vascularisation and wound healing in diabetic mice (2013) (44)
Intraoperative multiplane transesophageal echocardiography for guiding direct myocardial gene transfer of vascular endothelial growth factor in patients with refractory angina pectoris. (1999) (42)
Repair of Ischemic Heart Disease with Novel Bone Marrow-Derived Multipotent Stem Cells (2005) (37)
Estradiol-induced, endothelial progenitor cell-mediated neovascularization in male mice with hind-limb ischemia (2009) (37)
Plasma vascular endothelial growth factor (VEGF) levels after intramuscular and intramyocardial gene transfer of VEGF-1 plasmid DNA. (2002) (36)
Magnetic resonance mapping of transplanted endothelial progenitor cells for therapeutic neovascularization in ischemic heart disease. (2004) (35)
Tumor necrosis factor-α signaling via TNFR1/p55 is deleterious whereas TNFR2/p75 signaling is protective in adult infarct myocardium. (2011) (35)
The matrix revolutions: matrix metalloproteinase, vasculogenesis, and ischemic tissue repair. (2007) (33)
Percutaneous Myocardial Gene Transfer of phVEGF-2 (1999) (33)
Long-term stable expression of human growth hormone by rAAV promotes myocardial protection post-myocardial infarction. (2007) (32)
Cell therapy for critical limb ischemia: moving forward one step at a time. (2011) (32)
Tumor Necrosis Factor–Mediated E2F1 Suppression in Endothelial Cells: Differential Requirement of c-Jun N-Terminal Kinase and p38 Mitogen-Activated Protein Kinase Signal Transduction Pathways (2003) (30)
Frontiers in nephrology: the evolving therapeutic applications of endothelial progenitor cells. (2007) (30)
Estrogen Receptor–Mediated, Nitric Oxide–Dependent Modulation of the Immunologic Barrier Function of the Endothelium: Regulation of Fas Ligand Expression by Estradiol (2001) (29)
Regulation of Vascular Contractility and Blood Pressure by the E2F2 Transcription Factor (2009) (29)
Adrenal androgen dehydroepiandrosterone sulfate inhibits vascular remodeling following arterial injury. (2009) (29)
Gli3 Regulation of Myogenesis Is Necessary for Ischemia-Induced Angiogenesis (2013) (28)
Safety and efficacy of peripheral blood progenitor cell mobilization and collection in patients with advanced coronary heart disease (2006) (27)
Safety and efficacy of plasmid DNA expressing two isoforms of hepatocyte growth factor in patients with critical limb ischemia (2015) (27)
Excimer laser atherectomy. The greening of Sisyphus. (1990) (27)
PreSERVE-AMINovelty and Significance (2017) (26)
E2F1 suppresses cardiac neovascularization by down-regulating VEGF and PlGF expression. (2014) (25)
Enhanced potency of cell-based therapy for ischemic tissue repair using an injectable bioactive epitope presenting nanofiber support matrix. (2014) (25)
Estradiol Triggers Sonic-hedgehog–induced Angiogenesis During Peripheral Nerve Regeneration by Downregulating Hedgehog-interacting Protein (2011) (24)
Hyperhomocyst(e)inemia impairs angiogenesis in a murine model of limb ischemia (2005) (24)
Genetic targeting for cardiovascular therapeutics: are we near the summit or just beginning the climb? (2001) (23)
Pulmonary gas transfer related to markers of angiogenesis during the menstrual cycle. (2008) (23)
IL-10 Accelerates Re-Endothelialization and Inhibits Post-Injury Intimal Hyperplasia following Carotid Artery Denudation (2016) (23)
Wnt11 Gene Therapy with Adeno-associated Virus 9 Improves Recovery from Myocardial Infarction by Modulating the Inflammatory Response (2016) (23)
Engineering the Response to Vascular Injury Divergent Effects of Deregulated E2F1 Expression on Vascular Smooth Muscle Cells and Endothelial Cells Result in Endothelial Recovery and Inhibition of Neointimal Growth (2003) (22)
Catheter-based intravascular ultrasound discriminates bicuspid from tricuspid valves in adults with calcific aortic stenosis. (1990) (22)
Estradiol promotes neural stem cell differentiation into endothelial lineage and angiogenesis in injured peripheral nerve (2012) (22)
Enhanced voluntary alcohol consumption after estrogen supplementation negates estrogen-mediated vascular repair in ovariectomized mice. (2007) (22)
Double face of VEGF. (2005) (21)
Ethanol modulation of TNF-alpha biosynthesis and signaling in endothelial cells: synergistic augmentation of TNF-alpha mediated endothelial cell dysfunctions by chronic ethanol. (2005) (21)
OESTROGEN RECEPTORS AND CARDIOVASCULAR DISEASE * (1996) (20)
Therapeutic angiogenesis by gene transfer in critical limb and myocardial ischemia. (2003) (20)
Progenitor cell release plus exercise to improve functional performance in peripheral artery disease: the PROPEL Study. (2013) (20)
Pulmonary gas transfer related to markers of angiogenesis during the menstrual cycle (2007) (20)
Factores de crecimiento para la angiogénesis terapéutica en las enfermedades cardiovasculares (2001) (20)
Vascular endothelial growth factor-induced angiogenesis: crouching tiger or hidden dragon? (2001) (19)
Gene therapy for cardiovascular angiogenesis (2003) (18)
Functionally Novel Tumor Necrosis Factor-&agr;–Modulated CHR-Binding Protein Mediates Cyclin A Transcriptional Repression in Vascular Endothelial Cells (2002) (17)
Loss of the Cytoskeletal Protein Pdlim7 Predisposes Mice to Heart Defects and Hemostatic Dysfunction (2013) (17)
Limitations of color flow Doppler imaging in the quantification of valvular regurgitation: velocity of regurgitant jet, rather than volume, determines size of color Doppler image. (1993) (17)
Autologous CD34+ Cell Therapy for Ischemic Tissue Repair. (2019) (16)
Challenges in the Translation of Cardiovascular Cell Therapy (2010) (16)
Biological approaches to ischemic tissue repair: gene- and cell-based strategies (2008) (15)
Stem cells review series: an introduction. (2011) (15)
Pathology of mitral commissurotomy performed with the Inoue catheter: implications for mechanisms and complications. (1994) (15)
Gene therapy for restenosis: biological solution to a biological problem. (2007) (15)
E2F1 Suppresses Oxidative Metabolism and Endothelial Differentiation of Bone Marrow Progenitor Cells (2018) (14)
All in the family: VEGF-B joins the ranks of proangiogenic cytokines. (2003) (13)
Mesenchymal Stem Cells Biology, Pathophysiology, Translational Findings, and Therapeutic Implications for Cardiac Disease (2011) (13)
Angiogenic gene therapy: pre-clinical studies and phase I clinical data. (2002) (13)
Incidence and clinical significance of cardiac biomarker elevation during stem cell mobilization, apheresis, and intramyocardial delivery: an analysis from ACT34-CMI. (2012) (13)
CD34 + cell therapy significantly reduces adverse cardiac events, health care expenditures, and mortality in patients with refractory angina (2020) (12)
Manual of Research Techniques in Cardiovascular Medicine (2014) (12)
A big promise from the very small identification of circulating embryonic stem-like pluripotent cells in patients with acute myocardial infarction. (2009) (11)
Lipids, lipoproteins, fibrinogen and fibrinolytic activity in angiographically assessed coronary heart disease. (1987) (11)
Biological revascularization and the interventional molecular cardiologist: bypass for the next generation. (2002) (11)
Abstract 5638: Autologous CD34+ Cell Therapy for Refractory Angina: 12 Month Results of the Phase II ACT34-CMI Study (2009) (11)
Endothelial Smoothened-dependent Hedgehog Signaling is Not Required for Sonic Hedgehog Induced Angiogenesis or Ischemic Tissue Repair (2018) (11)
In Memoriam (2002) (10)
Estrogen and Angiogenesis (2000) (10)
Transplant graft vasculopathy: a dark side of bone marrow stem cells? (2003) (10)
Alcohol Consumption Negates Estrogen-mediated Myocardial Repair in Ovariectomized Mice by Inhibiting Endothelial Progenitor Cell Mobilization and Function* (2013) (9)
A "hawk's beak" to identify the new transient midventricular Tako-Tsubo syndrome. (2008) (9)
Prevention and recovery of hibernating myocardium by microvascular repair. (2011) (9)
Navigating the Future of Cardiovascular Drug Development—Leveraging Novel Approaches to Drive Innovation and Drug Discovery: Summary of Findings from the Novel Cardiovascular Therapeutics Conference (2017) (9)
[Growth factors for therapeutic angiogenesis in cardiovascular diseases]. (2001) (9)
Pathology of unstable angina: Analysis of biopsies obtained by directional coronary atherectomy (2005) (8)
Chronic Myocardial Ischemia Endothelial Growth Factor 2 Gene Transfer by Catheter Delivery in Patients With Phase 1 / 2 Placebo-Controlled , Double-Blind , Dose-Escalating Trial of Myocardial Vascular (2002) (8)
Images in Cardiovascular Medicine: Percutaneous myocardial gene transfer of phVEGF-2. (1999) (8)
Phase II Clinical Trial of CD 34 + Cell Therapy to Explore Endpoint Selection and Timing in Patients With Critical Limb Ischemia (2014) (8)
Use of emergency balloon dilation to reverse acute hemodynamic decompensation developing during diagnostic catheterization for aortic stenosis (bailout valvuloplasty). (1989) (8)
Update on gene therapy for myocardial ischaemia and left ventricular systolic dysfunction or heart failure. (2010) (8)
Bioengineering to enhance progenitor cell therapeutics. (2009) (8)
Percutaneous balloon valvuloplasty: current status (1989) (7)
Randomized , Double-Blind , Placebo-Controlled Clinical Trial of Intracoronary Administration of Autologous CD 34 + Cells in Patients With Left Ventricular Dysfunction Post STEMI (2017) (6)
Reprint of: Development of bioactive peptide amphiphiles for therapeutic cell delivery. (2015) (6)
New Definition of Aging? Measuring Regenerative Capacity in Patients. (2016) (6)
Assessment of coronary arterial stenoses post-intervention by quantitative angiography versus intracoronary ultrasound in 13 patients undergoing balloon and/or laser coronary angioplasty (1991) (6)
STAT 3-Dependent Mouse Embryonic Stem Cell Differentiation Into Cardiomyocytes Analysis of Molecular Signaling and Therapeutic Efficacy of Cardiomyocyte Precommitted mES Transplantation in a Mouse Model of Myocardial Infarction (2007) (6)
Autologous CD34+ Stem Cell Therapy Increases Coronary Flow Reserve and Reduces Angina in Patients With Coronary Microvascular Dysfunction (2022) (6)
Current limitations of intravascular ultrasound for quantitative analysis of luminal narrowing (1990) (5)
Going mobile: enhanced recovery from myocardial infarction via stem cell mobilization and homing for tissue repair. (2014) (5)
Genetic deletion of TNFR2 augments inflammatory response and blunts satellite‐cell‐mediated recovery response in a hind limb ischemia model (2015) (5)
Use of recombinant adeno-associated viral vectors as a tool for labeling bone marrow cells. (2005) (5)
Cell-free Embryonic Stem Cell Extract-mediated Derivation of Multi-potent Stem Cells from NIH3T3 Fibroblasts for Functional and Anatomical Ischemic Tissue Repair (2007) (5)
Erratum: The cytoskeletal protein ezrin regulates EC proliferation and angiogenesis via TNF-α-induced transcriptional repression of cyclin A (Journal of Clinical Investigation (2005) 115 (1785-1796) DOI: 10.1172/JCI22849) (2005) (5)
3-Dimensional reconstruction of coronary and peripheral vessels from 2-D ivus images: Determination of optimal image acquisition rate during timed pullback (1991) (5)
Vascular applications of human gene therapy. (1995) (5)
Inoue balloon mitral valvuloplasty vs. double balloon technique: procedure duration and radiation exposure (1991) (4)
Erratum: Safety and efficacy of plasmid DNA expressing two isoforms of hepatocyte growth factor in patients with critical limb ischemia (Gene Therapy (2016) 23 (306-312)) DOI:10.1038/gt.2015.110) (2016) (4)
Erratum: Supramolecular nanostructures that mimic VEGF as a strategy for ischemic tissue repair (Proceedings of the National Academy of Sciences (2011) 108, 33 (13438-13443) DOI: 10.1073/ pnas.1016546108) (2012) (4)
Abstract of original contributions: 40th Annual Scientific SessionCombination balloon-ultrasound imaging catheter (BUIC) allows continuous monitoring of balloon inflation, deflation, and immediate recoil in patients undergoing balloon angioplasty (1991) (4)
Abstract 13688: Randomized, Double-Blind, Placebo-Controlled Pilot Trial of Autologous CD34+ Cell Therapy for Severe Intermittent Claudication: Interim Results (2011) (4)
Tumor Necrosis Factor – Mediated E 2 F 1 Suppression in Endothelial Cells Differential Requirement of c-Jun N-Terminal Kinase and p 38 Mitogen-Activated Protein Kinase Signal Transduction Pathways (2003) (4)
Abstract 16920: Randomized, Double-Blind, Placebo Controlled Trial of Autologous CD34+ Cell Therapy for Critical Limb Ischemia: 1 Year Results (2010) (4)
Derivation and characterization of bone marrow-derived multipotent stem cells. (2006) (4)
Career moves: induced pluripotent cells from human aortic smooth muscle cells can efficiently redifferentiate into parental phenotype. (2010) (3)
Abstract 5445: Gli2 and Gli3 Are Over-expressed in the Ischemic Tissue and Participate in Ischemia-induced Angiogenesis and Myogenesis (2008) (3)
DIRECT INTRAMYOCARDIAL GENE THERAPY WITH VEGF FOR INOPERABLE CORONARY ARTERY DISEASE: PRELIMINARY CLINICAL RESULTS (1999) (3)
Endothelial dysfunction and systemic hypertension by selective cGMP-dependent protein kinase I inhibition using novel cell-penetrating peptide delivered in vivo. (2013) (3)
Cardiovascular Gene Therapy (2003) (3)
Abstract 3957: RGDS-Epitope Presenting Peptide Amphiphile Nanofibers Enhance Regenerative Potency of Cell-based Strategies in Ischemic Tissue (2008) (3)
E 2 F 1 Suppresses Oxidative Metabolism and Endothelial Differentiation of Bone Marrow Progenitor Cells (2018) (3)
Ischemic tissue repair by autologous bone marrow-derived stem cells: scientific basis and preclinical data. (2007) (3)
Jeffrey M. Isner, MD (2002) (3)
3-dimensional reconstruction of vascular lumen from images recorded during percutaneous 2-D intravascular ultrasound (1990) (3)
Abstract 11770: Cardiac Biomarker Elevation during Stem Cell Mobilisation, Apheresis and Intramyocardial Delivery is Common but does not Impact Incidence of Long-Term MACE: An Analysis from ACT34-CMI (2012) (3)
Clinical trials of myocardial VEGF gene transfer (2001) (2)
Reprogrammed Human Endothelial Cells: A Novel Cell Source for Regenerative Vascular Medicine. (2017) (2)
Safety and efficacy of plasmid DNA expressing two isoforms of hepatocyte growth factor in patients with critical limb ischemia (2016) (2)
A Path Forward for Regenerative Medicine: Navigating Regulatory Challenges Summary of Findings From the Cardiac Safety Research Consortium/Texas Heart Institute International Symposium on Cardiovascular Regenerative Medicine (2018) (2)
Biomaterials to Enhance Stem Cell Function in the Heart Mesenchymal Stem Cells: Biology, Pathophysiology, Translational Findings, and Therapeutic Implications for Cardiac (2011) (2)
The (Translational) Road Less Traveled. (2018) (2)
Vascular applications of human gene therapy (2005) (2)
ONE YEAR FOLLOW-UP RESULTS FROM PRESERVE-AMI: A RANDOMIZED, DOUBLE-BLIND, PLACEBO CONTROLLED CLINICAL TRIAL OF INTRACORONARY INFUSION OF AUTOLOGOUS CD34+ CELLS IN PATIENTS WITH LEFT VENTRICULAR DYSFUNCTION POST STEMI (2015) (2)
Right atrial Merkel cell carcinoma metastasis. (2010) (2)
A PHASE 2, DOUBLE-BLIND, RANDOMIZED, PLACEBO-CONTROLLED, MULTICENTER TRIAL OF THE SAFETY AND EFFICACY OF PLASMID DNA EXPRESSING 2 ISOFORMS OF HEPATOCYTE GROWTH FACTOR IN PATIENTS WITH CRITICAL LIMB ISCHEMIA (2014) (2)
Phase 2 Study of Intramyocardial Injection of Autologous CD34+ Cells to Treat Subjects with Refractory Chronic Myocardial Ischemia (CMI): Factors Influencing Mobilization and Apheresis. (2009) (2)
3-Dimensional reconstruction of balloon dilated coronary, renal, and femoropopliteal arteries from 2-D intravascular ultrasound images: Analysis of longitudinal sagittal versus cylindrical views (1991) (2)
Mending the broken heart: ischemic preconditioning-stimulated myocardial angiogenesis. (2004) (2)
Autologous CD34 Cell Therapy for Treatment of Coronary Microvascular Dysfunction in Patients With Angina and Non-Obstructive Coronary Arteries (2019) (2)
On-line 3-D reconstruction of 2-D intravascular ultrasound images during balloon angioplasty: Clinical application in patients undergoing percutaneous balloon angioplasty (1991) (2)
A Big Promise from the Very Small : Identification of Circulating ES-like Pluripotent Cells in Patients with Acute Myocardial Infarction (2009) (2)
Design of a confirmatory pivotal study with intramyocardial GCSF-mobilized autologous CD34 cells (CLBS14) for the treatment of an orphan-sized population with no-option refractory disabling angina (2020) (1)
Abstract 15645: Exosomes from Human CD34+ Cells Are a Crucial Paracrine Component for Ischemic Tissue Repair and Angiogenesis (2011) (1)
Estrogen augments incorporation of bone marrow-derived endothelial progenitor cells into sites of myocardial neovascularization (2003) (1)
Abstract 1277: STAT3-dependent mouse Embryonic Stem Cell Differentiation into Cardiomyocytes: Analysis of Molecular Signaling and Therapeutic Efficacy of Cardiomyocyte Pre-committed mES in a Mouse Model of Myocardial Infarction (2007) (1)
Intravascular Ultrasound: Potential for Optimizing Mechanical Solutions to Restenosis (1992) (1)
Losordo of Age Therapeutic Angiogenesis for Critical Limb Ischemia : Microvascular Therapies Coming (2008) (1)
IMPACT OF MOBILIZATION ABILITY ON CELL FUNCTIONALITY AND COMPARISON OF NORMAL AND CMI SUBJECT SAMPLES: AN ANALYSIS FROM ACT34–CMI (2013) (1)
Abstract 16186: Hypoxic Pre-conditioning on Human CD34+ Stem Cells Enhances Exosome Therapeutics of Ischemic Tissue Repair Through ETS-1-Regulated Pathway (2015) (1)
Laser myoplasty for hypertrophic cardiomyopathy: Use of a thermocouple to continuously monitor laser-fiber contact with myocardium and for dosimetry (1991) (1)
Dynamics of vascular remodeling: An overview and bibliography (2004) (1)
Transesophageal echocardiographic guidance during percutaneous laser myoplasty for hypertrophic cardiomyopathy: Results of a canine trial (1990) (1)
Abstract 11777: A Phase 3, Randomized, Partially Blinded, Active-Controlled, Study Assessing the Efficacy and Safety of Intramyocardial Autologous CD34+ Cell Administration in Patients with Refractory Angina: Design of the RENEW Study (2012) (1)
3-dimensional intravascular ultrasound imaging of human coronary arteries after percutaneous revascularization (1991) (1)
Cell Therapy for Cardiac Disease (2012) (1)
The pharmacology of angiogenesis in cardiovascular disease (2005) (1)
Bone‐marrow‐derived Cells in Myocardial Repair and Regeneration (2007) (1)
Editor's Comment on: Development of bioactive peptide amphiphiles for therapeutic cell delivery. (2015) (1)
Gene Therapy for Angiogenesis in the Treatment of Cardiovascular and Peripheral Arterial Disease (2005) (1)
Increased surface expression of the vitronectin-receptor αvβ3 in human endothelial cells correlates with survival (1998) (1)
3 Src Blockade Stabilizes a Flk/Cadherin Complex, Reducing Edema and Tissue Injury Following Myocardial Infarction(Angiogenesis-Clinical and Experimental New Findings,Symposium 3 (SY3) (H),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society) (2006) (1)
OE-210 Transplantation of GCSF-Mobilized Endothelial Progenitor Cells Is More Beneficial for Cardiovascular Regeneration Compared to That of GCSF-mobilized Total Mononuclear Cells(Angiogenesis 1 (M) : OE26)(Oral Presentation (English)) (2004) (1)
CXCR4 Antagonist AMD3100 Promotes Cardiac Functional Recovery After Ischemia-Reperfusion Injury via eNOS-Dependent Mechanism (2012) (1)
Angels and Demons: part II. (2013) (1)
Design of a potentially registrational study of sakigake-designated GCSF-Mobilized autologous CD34 cell (CLBS12) Therapy of no-option critical limb ischemia including arteriosclerosis obliterans and Buerger's Disease (2020) (1)
Abstract 2099: AAV9-Wnt11 Gene Therapy Improves Cardiac Recovery After Myocardial Infarction by Modulating the Inflammatory Response (2009) (1)
Abstract 3701: CXCR4 Antagonist AMD3100 Preserves Cardiac Function After Ischemia-Reperfusion Injury via eNOS Dependent Mobilization of Bone Marrow Derived Progenitor Cells (2009) (0)
Abstract 10186: Re-establishment of SDF-1 Expression Through Non-viral Gene Therapy (JVS-100) Significantly Improves Clinical Parameters In Patients with Ischemic Class III Heart Failure (2011) (0)
Abstract 11252: E2F1 Suppresses Cardiac Neovascularization by Downregulating VEGF and PlGF Expression (2011) (0)
Abstract 3330: Genetic Deletion of CXCR4 in Cardiomyocytes Leads to Heart Failure (2009) (0)
Abstract 5057: CXCR4 Antagonist AMD3100 Preserves Cardiac Function After Myocardial Infarction (MI) via CXCR4 Dependent and Independent Pathways (2009) (0)
Abstract 18544: A Critical Role of Src Family Kinase (SFK) in SDF-1/CXCR4-Mediated Bone-Marrow Progenitor-Cell Homing to Ischemic Cardiac Tissue (2010) (0)
Abstract 16109: A Selective Cargo of Non-coding RNAs Mediate Therapeutic Potential of Human CD34+ Stem Cell-derived Exosomes (2015) (0)
Estradiol promotes neural stem cell differentiation into endothelial lineage and angiogenesis in injured peripheral nerve (2012) (0)
Abstract 359: Human CD34+ Cell-Derived Exosomes Target Endothelial Cells to Deliver MiR-126 Promoting Revascularization and Myocardial Repair (2013) (0)
Biological Revascularization : New Hope for Patients(The 69th Annual Scientific Meeting of the Japanese Circulation Society) (2005) (0)
Abstract 2094: Hemeoxygenase-1 Gene Modification Enhances the Regenerative Efficacy of CD34+Cell-Therapy After Myocardial Infarction (2009) (0)
Abstract 125: The E2F1 Transcription Factor Suppresses Cardiac Fibrosis via Downregulating Syndecan-4 Expression and Smad2/3 Phosphorylation (2015) (0)
Book Review Angiogenesis: An Integrative Approach from Science to Medicine Edited by William D. Figg and Judah Folkman. 601 pp., illustrated. New York, Springer, 2008. $149. 978-0-387-71517-9 (2008) (0)
Abstract 443: Transcription Factor E2F2 Regulates Vessel Contractile Function and Blood Pressure via Isoform-specific Expressions of Endothelin Converting Enzyme-1 (2007) (0)
Abstract 1279: Combined Stem Cell Mobilization via CXCR4 Antagonist Augments Recruitment of EPCs Following Sonic Hedgehog Gene Therapy via Increased Local Expression of VEGF and SDF-1 (2007) (0)
Abstract 3656: Estradiol Improves Neural Functional Recovery After Nerve Injury by Reducing Inhibition of the Hedgehog-signaling Pathway (2008) (0)
554. Improved Efficiency of Gene Expression Using the Stiletto™ Endocardial Direct Injection Catheter (2006) (0)
Cytokines Therapeutic Angiogenesis and Vasculogenesis for Ischemic Disease: Part I: Angiogenic (2014) (0)
Ischemia-Reperfusion Injury via eNOS-Dependent Mechanism CXCR4 Antagonist AMD3100 Promotes Cardiac Functional Recovery After (2012) (0)
Angiogenic, arteriogenic, and vasculogenic properties of sonic hedgehog gene therapy in an experimental model of ischemia (2012) (0)
Viewpoints The (Translational) Road Less Traveled (2018) (0)
Percutaneous Biological Revascularization (2003) (0)
Abstract 317: Differential Role of Estrogen Receptors Alpha and Beta in Estradiol (E2) Enhanced Contribution of Bone Marrow-Derived Endothelial Progenitor Cells to Neovascularization after Ischemic Injury (2006) (0)
IL-10 Suppresses Pro-Inflammatory Cytokine Mediated Cardiac Dysfunction and Remodeling after Myocardial Infarction (2008) (0)
Sonic Hedgehog Gene Therapy Induces Arteriogenesis in Myocardial Ischemia(Angiogenesis 3 (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society) (2005) (0)
Getting Back to Normal: Can Enhanced Regeneration Maintain Health? (2016) (0)
Abstract 17103: VEGF-Mimicking Nanostructures for Ischemic Tissue Repair (2011) (0)
Abstract 6: Therapeutic Angiogenesis by Human CD34+ Hematopoietic Stem Cells via Exosomes-Mediated MicroRNA Transfer (2012) (0)
Abstract 19522: Modification of Hemeoxygenase-1 Expression Enhances the Therapeutic Potency of CD34+ Cells in Ischemic Tissue Repair (2010) (0)
Abstract 15621: Randomized, Double-Blind, Placebo-Controlled Trial of Autologous CD34+ Cell Therapy for Refractory Angina: 2-Year Safety Analysis (2010) (0)
Corrigendum to “Gene therapy for restenosis: Biological solution to a biological problem” [J. Mol. Cell. Cardiol. 42 (2007) 461–468] (2007) (0)
Abstract 1475: Small molecule CXCR4 Antagonist Augments Mobilization and Incorporation of Bone Marrow-Derived Endothelial Progenitor Cells into Sites of Myocardial Neovascularization and Reduces Mortality After Myocardial Infarction (2006) (0)
increased intensity of hypoxic exercise -adrenergic receptor activation with β independent of Nitric oxide-mediated vasodilation becomes (2015) (0)
Therapeutic Angiogenesis-Now and Future(Therapeutic Angiogenesis-Now and Future, The 69th Annual Scientific Meeting of the Japanese Circulation Society) (2005) (0)
Abstract 15882: Ablation of E2F3 in Endothelial Cells Impairs the Functional Recovery of Heart and Limb from Ischemic Injury (2011) (0)
Abstract 5278: The Sonic Hedgehog Transcription Factor Gli3 Modulates Ischemia-induced Angiogenesis (2008) (0)
Abstract 12015: Clinical Parameters Influencing Cell Mobilization and Impact of Mobilization Ability on Efficacy Outcomes: An Analysis from ACT34-CMI (2012) (0)
at rest and during rhythmic exercise in humans Skeletal muscle blood flow responses to hypoperfusion (2015) (0)
Fox transcription factors in corneal angiogenesis (2013) (0)
OE-322 Synergistic Effect of Bone Marrow Stem/Progenitor Cell Mobilization and VEGF-2 Gene Transfer in Chronic Myocardial Ischemia(Gene Therapy 2 (IHD) : OE41)(Oral Presentation (English)) (2004) (0)
Abstract 180: Alcohol Consumption Negatively Competes with Estrogen-Mediated Myocardial Repair in Ovariectomized Mice: Ethanol-Mediated Suppression of Estradiol-Induced Survival Signaling in Endothelial Progenitor Cells (2012) (0)
Gene and Cell Therapy for Tissue Regeneration : A New Era in Cardiovascular Disease Management(Keynote Lecture)(Angiogenesis and Regeneration Medicine in Cardiovascular Medicine (M) : FRS2)(Featured Research Session (English)) (2004) (0)
N009 Enhancement of Sonic Hedgehog-induced cardiac functional recovery is augmented by CXCR4 antagonist via MMP-9-dependent pathway after myocardial infarction (2009) (0)
Targeting lung damage in COVID-19 patients with CD34+ cell therapy (2020) (0)
Long-Term Expression of Human Growth Hormone by rAAV Protects Cardiac Myocytes after Myocardial Infarction in Rats (2006) (0)
Cardiac valve malformations: New insights from Pdlim7, an unexpected suspect in heart development (2011) (0)
Functional Recovery of Nerve Conduction and Blood Flow by Sonic Hedgehog in an Experimental Diabetic Neuropathy(Peripheral Circulation/Vascular Disease (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society) (2005) (0)
Direct Actions of Estrogen on Vascular Cells Ameliorates Response to Injury (1999) (0)
Gene Therapy for Angiogenesis (2006) (0)
Inflammation Induced Lymphangiogenesis in the Cornea Arises From Innate Immune Cells (2005) (0)
progenitor cells Exosomes and Cardiac Repair After Myocardial Infarction (0)
Abstract 19789: Specifically Designed, Bioactive Nanofiber-Matrix Supports Cell-based Therapy in Ischemic Tissue Repair (2010) (0)
OE-236 Genetic Modification with Sonic Hedgehog Ameliorates Aging-induced EPC Dysfunction and Augments Therapeutic Angiogenesis of Endogenous EPCs Following Acute Myocardial Infarction(Regeneration(angiogenesis/myocardial regeneration)(01)(M),Oral Presentation(English),The 72nd Annual Scientific Mee (2008) (0)
Sonic Hedgehog Gene Therapy Improves Cardiac Function in Rat model of Acute Myocardial Ischemia(Acute Myocardial Infarction, Basic 2 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society) (2005) (0)
Sonic Hedgehog Gene Therapy Improves Cardiac Function in Pig Model of Chronic Myocardial Ischemia(Gene Therapy 3 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society) (2005) (0)
Reply to Chakrabarti et al.: Corneal angiogenesis in patients with null FOXC1 variants (2012) (0)
Abstract 3804: Enhancement of Sonic Hedgehog-induced Cardiac Functional Recovery is Augmented by CXCR4 Antagonist via MMP-9-dependent Pathway after Myocardial Infarction (2008) (0)
ELECTROMECHANICAL ASSESSMENT OF MYOCARDIAL FUNCTION (NOGA) IS ASSOCIATED WITH EXERCISE IMPROVEMENT IN PATIENTS TREATED WITH AUTOLOGOUS STEM CELL THERAPY FOR REFRACTORY ANGINA (2013) (0)
Abstract 19109: Hypoxia-Induced Reprogramming of Exosomal MicroRNAs From Human CD34+ Progenitor Cells Promotes Its Angiogenic Activity and Ischemic Tissue Repair (2013) (0)
Abstract 256: Paracrine miRNA-Crosstalk Between Human CD34+ Stem Cells and Selective Myocardial Cells Via Therapeutic Exosomes Promotes Repair of the Ischemic Heart (2014) (0)
Therapies Therapeutic Angiogenesis and Vasculogenesis for Ischemic Disease: Part II: Cell-Based (2014) (0)
Abstract 1329: Intramuscular Gene Transfer of Human Sonic Hedgehog Ameliorates Monocrotaline-induced Pulmonary Hypertension in Rats (2006) (0)
1104-192 Heterologous transplantation of CD34+cells from patients with coronary ischemia leads to myocardial salvage and enhanced functional recovery in murine model of myocardial infarction (2004) (0)
Abstract 18915: Modulation of Exosomal Pro-angiogenic MicroRNAs from CD34+ Progenitor Cells by Hypoxic-Preconditioning Enhances its Angiogenic Potency and Post-ischemic Tissue Repair (2012) (0)
Cell Therapy for Acute Myocardial Infarction (2006) (0)
Vascular applications of human gene therapy (1995) (0)
Abstract 5371: Bone Marrow MMP-9 Expression Mediates Therapeutic Effect of Selective CXCR4 Antagonist AMD3100 on Myocardial Infarction (2008) (0)
Stem Cell Therapy for Peripheral Arterial Disease (2008) (0)
Abstract 305: Tumor Necrosis Factor-{alpha} p75 Receptor, Satellite-Cell Survival, Activation and Muscle Regeneration (2007) (0)
Acetylcysteine to prevent angiography related renal toxicity (2001) (0)
Comment Excimer Laser Atherectomy The Greening of Sisyphus (2005) (0)
Peripheral Circulation in Vascular Disease(Peripheral Circulation/Vascular Disease (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society) (2005) (0)
Abstract P019: Exosomes from Human CD34+ Cells: Critical Mediators of Proangiogenic Paracrine Effect of EPCs (2011) (0)
Abstract 15491: Myocardial Infarction-Induced Mobilization of Bone Marrow-Endothelial Progenitor Cells is Modulated By IL-10 Signaling and is Influenced by SDF1-CXCR4 Signaling Axis (2011) (0)
Abstract 467: Neural Stem Cells Contribute to Peripheral Nerve Repair by Coordinated Angiogenesis and Neurogenesis (2007) (0)
5 Notch Signaling Mediates Endothelial Progenitor Cell Fate in Injury-induced Arterial Remodeling under High Cholesterol Condition(A New Era in Atherosclerosis Research, The 71st Annual Scientific Meeting of the Japanese Circulation Society) (2007) (0)
Percutaneous laser myoplasty for treatment of hypertrophic cardiomyopathy (1990) (0)
Abstract 16163: Foxc2 is Required for Neovascularization During Ischemic Tissue Repair After Myocardial Infarction (2011) (0)
Endothelial Progenitor Cells Are Rapidly Recruited to Myocardium and Mediate Protective Effect of Ischemic Preconditioning via “Imported” Nitric Oxide Synthase Activity Heart Failure (2005) (0)
Cytokine Treatment for Cardioprotection and Cardiac Regeneration (2007) (0)
404-5 Vascular endothelial growth factor (VEGF) plays a central role in the development of diabetic cardiomyopathy and gene transfer of VEGF improves heart failure in long-standing streptozotocin-induced diabetic rat (2004) (0)
Sahoo and Losordo Exosomes in Myocardial Repair After Ischemia (2014) (0)
Abstract 15515: Exosomes from Adult Human CD34+ Stem Cells Transfer Crucial Pro-Angiogenic MiRNA Inducing Functional Changes in Target Cells (2011) (0)
Abstract P186: IL-10 Mitigates Adverse Cardiac Remodeling and Improves Left Ventricle Function in Pressure Overload--Induced Hypertrophy (2011) (0)
Abstract 20041: Human CD34+ Stem Cell-Derived Exosomes Mediate the Paracrine miRNA-Crosstalk with Cardiomyocytes and Endothelial Cells Promoting Repair of the Ischemic Heart (2014) (0)
Abstract 5635: Estradiol Promotes Neural Stem Cell-based Peripheral Nerve Repair by Enhancing Angiogenesis (2009) (0)
Chapter 13 – Effects of Statins on Endothelial Progenitor Cells: Mobilization, Differentiation, and Contribution to Adult Neovascularization (2004) (0)
Sonic Hedgehog Promotes Myocardial Proliferation in Animal Models of Myocardial Ischemia(Heart Failure, Basic 1 (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society) (2005) (0)
Abstract 1962: CXCR4-mediated Bone Marrow Stem Cell Homing and Niche Maintenance Is Modulated by the Functional Status of c-kit (2008) (0)
Moving Forward One Step at a Time (2011) (0)
Abstract 14703: Cell-Free Exosomes from Human CD34+ Progenitor Cells Induce Therapeutic Angiogenesis via Targeted Delivery of Mir-126 to Endothelial Cells (2012) (0)
2007 Thomas W. Smith Memorial Lecture—Biologic Tissue Repair: Tearing Pages out of Nature’s Playbook (2007) (0)
CHANGES IN NON-INVASIVE CORONARY FLOW RESERVE BY PET AFTER INTRAMYOCARDIAL, AUTOLOGOUS CD34+ CELL THERAPY FOR ISCHEMIC CARDIOMYOPATHY (2011) (0)
Abstract 14741: Autologous Cd34+ Cells (clbs119) for Repair of Covid-19 Induced Microvascular Lung Damage: Rationale and Study Design (2020) (0)
Angiogenic Cytokines Therapeutic Angiogenesis and Vasculogenesis for Ischemic Disease: Part I: (2011) (0)
Abstract 1616: Reconstitution of Embryonic Signaling via Sonic Hedgehog Gene Therapy Ameliorates Aging-induced EPC Dysfunction and Augments EPC-mediated Therapeutic Angiogenesis in Acute Myocardial Infarction (2006) (0)
Intravascular ultrasound of renal arteries in patients undergoing percutaneous transluminal angioplasty: Feasibility, safety and initial findings, including 3 dimensional reconstruction of renal arteries (1991) (0)
Compositions et méthodes pour traiter un infarctus du myocarde (2007) (0)
Abstract 235: Sonic Hedgehog Induces Angiogenesis via Rho Kinase-dependent MMP-9 and Osteopontin Expression (2008) (0)
Nouvelles cellules souches multipotentes (2004) (0)
Progesterone treated mice show decreased endothelial progenitor cell counts and impaired neovascularization in a model for hind limb ischemia: A-189 (2005) (0)
Abstract 19295: Genetic Deletion of E2F1 Protects Myocardium from Ischemic Injury by Upregulating Angiogenic Growth Factors (2012) (0)
Honedra® (CLBS12) autologous CD34+ cells improve outcomes in patients with Buerger’s disease (2021) (0)
Abstract 707: Tumor Necrosis Factor-alpha p75 Receptor, Sattelite-Cell Activation and Neovascularization (2006) (0)
Peripheral Arterial Disease (2016) (0)
Abstract 18036: Exosomes From Human CD34+ Cells Mediate Angiogenic Effects in vitro and in vivo (2010) (0)
Integrative Physiology Sonic Hedgehog–Modified Human CD34 Cells Preserve Cardiac Function After Acute Myocardial Infarction (2012) (0)
Abstract 17903: Cardioprotection by Exogenously Administered Endothelial Progenitor Cells (EPCs) After Ischemia-Reperfusion Injury is eNOS Dependent (2010) (0)
Abstract 12754: Infused CD34 Cell Dose, not Bone Marrow CD34+ Cell Content, Improves Clinical Outcomes and LVEF in Patients With Left Ventricular Dysfunction post STEMI: Results of the PreSERVE-AMI Trial (2015) (0)
Response to Letter Regarding Article “Atherosclerosis 2005: Recent Discoveries and Novel Hypotheses” (2006) (0)
256 Combination of Sonic Hedgehog and a CXCR4 Antagonist improves functional recovery via an MMP-9-dependent Pathway after Myocardial Infarction (2010) (0)
Abstract 2: IL-10 Modulates Mobilization of Bone Marrow Endothelial Progenitor Cells and Enhances Their Survival and Angiogenic Properties in Ischemic Myocardium (2011) (0)
Abstract 3667: Single Dose CXCR4 Antagonist Enhances Recovery From Ischemia Reperfusion Injury While Continuous Blockade Abolishes Treatment Effect (2009) (0)
Estrogen Receptors (cid:1) and (cid:2) Mediate Contribution of Bone Marrow–Derived Endothelial Progenitor Cells to Functional Recovery After Myocardial Infarction (2006) (0)
Getting Back to Normal (2016) (0)
3P-0635 A combo-therapy with angiogenic cytokine gene and bone marrow mobilization for ischemic heart disease (2003) (0)
Abstract 20070: Hypoxic Reprogramming of Exosomal miRNAs by Ets Transcription Factors in Human CD34+ Stem Cells Promotes Ischemic Tissue Repair (2014) (0)
Abstract 2960: HuR Knockdown Attenuates Post-MI Left Ventricular Dysfunction and Remodeling via Enhanced mRNA Degradation of Pro-inflammatory Cytokines and Inhibition of P53-mediated Apoptosis and TGF-beta-mediated Fibrosis in IL-10 Knock-out Mice (2009) (0)
Abstract 19049: MiR-126 Containing Exosomes From Human CD34+ Stem Cells Activate Endothelial Cells to Initiate Angiogenesis and Ischemic Tissue Repair (2013) (0)
Angiogenesis in the Treatment of Critical Limb Ischemia (2014) (0)
Abstract 1012: Notch Signaling Mediates Endothelial Progenitor Cell Fate in Injury-induced Arterial Remodeling under High Cholesterol Condition (2006) (0)
TCT-821 Intramyocardial Autologous CD34+ Cell Therapy Reduces Mortality and Improves Exercise Capacity in Patients with Refractory Angina. (2016) (0)
229. Use of rAAV Transduced Endothelial Progenitor Cells for the Treatment of Myocardial Infarction in Rat Model (2006) (0)
Abstract 14519: CXCR4 Protects Cardiomyocytes From Beta-Adrenergic Stress-Induced Apoptosis (2011) (0)
542A ABSTRACTS-Young Investigators Awards YOUNG INVESTIGATORS AWARDS COMPETITION (2016) (0)
D002 Sonic hedgehog induces angiogenesis via Rho kinase—dependent MMP-9 and osteopontin expression (2009) (0)
Abstract 1820: Derivation of Multipotent Stem Cells from Epigenetically Modified Endothelial Progenitor Cells (2008) (0)
Abstract 646: Isoform-Specific Dysregulation of Endothelin Converting Enzyme-1 and Hypertension in E2F2-Deficient Mice (2006) (0)
195. Therapeutic Angiogenesis in Mouse Ischemic Heart after Intramyocardial Injection of a Novel Two Gene Plasmid Vector Co-Expressing High Levels of Human VEGF and bFGF Genes (2004) (0)
Abstract 1117: Genetic Modification with Sonic Hedgehog Mitigates Aging-induced EPC Dysfunction and Augments Therapeutic Angiogenesis of Endogenous EPCs following Acute Myocardial Infarction (2007) (0)
of Circulating Angiogenic Cell Response to Angiogenic Stimuli Nitric Oxide Synthase Expression and Functional Response to Nitric Oxide Are Both Important Modulators (2015) (0)
OE-325 Human Sonic Hedgehog Gene Therapy Ameliorates Monocrotaline-induced Pulmonary Hypertension in Rats(Pulmonary circulation-1, The 71st Annual Scientific Meeting of the Japanese Circulation Society) (2007) (0)
Abstract 13139: In Vivo Differentiation of Epigenetically Reprogrammed Mouse and Human Endothelial Progenitor Cells into Cardiomyocytes Enhances Functional and Anatomical Post-Infarct Myocardial Repair (2011) (0)
Lymphangiogenesis In A Diabetic Murine Model (2006) (0)
Qualitative assessment of peripheral vessels by intravascular ultrasound before and after interventions (1990) (0)
Abstract 206: Stem Cell-derived Exosomes Induce Cardiac Repair via mRNA Modification (2016) (0)
Abstract 17214: Autologous CD34+ Cell Therapy Reduces Mortality and Improves Exercise Capacity in Patients With Refractory Angina (2016) (0)
hTERT transfection increases the potential of circulating endothelial progenitor cells (EPCs) in acute ischemic rat hearts (2004) (0)

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