Drew Weissman
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American immunologist
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Biology Philosophy
Drew Weissman's Degrees
- Doctorate Medicine Boston University
- PhD Immunology Boston University
Why Is Drew Weissman Influential?
(Suggest an Edit or Addition)According to Wikipedia, Drew Weissman is an American physician and immunologist known for his contributions to RNA biology. Weissman is the inaugural Roberts Family Professor in Vaccine Research, director of the Penn Institute for RNA Innovation, and professor of medicine at the Perelman School of Medicine at the University of Pennsylvania .
Drew Weissman's Published Works
Published Works
- A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms (2001) (2879)
- mRNA vaccines — a new era in vaccinology (2018) (2038)
- Suppression of RNA recognition by Toll-like receptors: the impact of nucleoside modification and the evolutionary origin of RNA. (2005) (1392)
- mRNA Is an Endogenous Ligand for Toll-like Receptor 3* (2004) (969)
- Incorporation of pseudouridine into mRNA yields superior nonimmunogenic vector with increased translational capacity and biological stability. (2008) (890)
- Zika virus protection by a single low dose nucleoside modified mRNA vaccination (2017) (624)
- Quantification of CD4, CCR5, and CXCR4 levels on lymphocyte subsets, dendritic cells, and differentially conditioned monocyte-derived macrophages. (1999) (601)
- Effect of Mycobacterium tuberculosis on HIV replication. Role of immune activation. (1996) (519)
- Generating the optimal mRNA for therapy: HPLC purification eliminates immune activation and improves translation of nucleoside-modified, protein-encoding mRNA (2011) (514)
- Expression kinetics of nucleoside-modified mRNA delivered in lipid nanoparticles to mice by various routes. (2015) (505)
- Inherited Resistance to HIV-1 Conferred by an Inactivating Mutation in CC Chemokine Receptor 5: Studies in Populations with Contrasting Clinical Phenotypes, Defined Racial Background, and Quantified Risk (1997) (465)
- Constitutive and induced expression of DC‐SIGN on dendritic cell and macrophage subpopulations in situ and in vitro (2002) (459)
- Small Interfering RNAs Mediate Sequence-Independent Gene Suppression and Induce Immune Activation by Signaling through Toll-Like Receptor 31 (2004) (456)
- Immunopathogenic Mechanisms of HIV Infection (1996) (413)
- Macrophage-tropic HIV and SIV envelope proteins induce a signal through the CCR5 chemokine receptor (1997) (384)
- Incorporation of pseudouridine into mRNA enhances translation by diminishing PKR activation (2010) (305)
- D614G Spike Mutation Increases SARS CoV-2 Susceptibility to Neutralization (2020) (296)
- Nucleoside-modified mRNA vaccines induce potent T follicular helper and germinal center B cell responses (2018) (292)
- mRNA vaccines for infectious diseases: principles, delivery and clinical translation (2021) (290)
- Differential N-Linked Glycosylation of Human Immunodeficiency Virus and Ebola Virus Envelope Glycoproteins Modulates Interactions with DC-SIGN and DC-SIGNR (2003) (255)
- Inhibition of Toll-like Receptor and Cytokine Signaling—A Unifying Theme in Ischemic Tolerance (2004) (254)
- Inhibition of HIV-1 Infection by Small Interfering RNA-Mediated RNA Interference1 (2002) (234)
- SARS-CoV-2 mRNA Vaccines Foster Potent Antigen-Specific Germinal Center Responses Associated with Neutralizing Antibody Generation (2020) (233)
- Administration of nucleoside-modified mRNA encoding broadly neutralizing antibody protects humanized mice from HIV-1 challenge (2017) (226)
- Increased Erythropoiesis in Mice Injected With Submicrogram Quantities of Pseudouridine-containing mRNA Encoding Erythropoietin (2012) (225)
- Tuberculosis and lung damage: from epidemiology to pathophysiology (2018) (215)
- Nanomaterial Delivery Systems for mRNA Vaccines (2021) (206)
- A Single Immunization with Nucleoside-Modified mRNA Vaccines Elicits Strong Cellular and Humoral Immune Responses against SARS-CoV-2 in Mice (2020) (201)
- Recent advances in mRNA vaccine technology. (2020) (201)
- Dendritic cells express multiple chemokine receptors used as coreceptors for HIV entry. (1998) (193)
- Three populations of cells with dendritic morphology exist in peripheral blood, only one of which is infectable with human immunodeficiency virus type 1. (1995) (192)
- CAR T cells produced in vivo to treat cardiac injury (2022) (188)
- Nucleoside modifications in RNA limit activation of 2′-5′-oligoadenylate synthetase and increase resistance to cleavage by RNase L (2011) (183)
- Nucleoside-modified mRNA immunization elicits influenza virus hemagglutinin stalk-specific antibodies (2018) (158)
- HIV Gag mRNA Transfection of Dendritic Cells (DC) Delivers Encoded Antigen to MHC Class I and II Molecules, Causes DC Maturation, and Induces a Potent Human In Vitro Primary Immune Response1 (2000) (156)
- Interleukin 10 blocks HIV replication in macrophages by inhibiting the autocrine loop of tumor necrosis factor alpha and interleukin 6 induction of virus. (1994) (153)
- Neutralizing antibody vaccine for pandemic and pre-emergent coronaviruses (2021) (152)
- HIV replication in CD4+ T cells of HIV-infected individuals is regulated by a balance between the viral suppressive effects of endogenous beta-chemokines and the viral inductive effects of other endogenous cytokines. (1996) (141)
- Immunopathogenic mechanisms of HIV infection. (1996) (134)
- Lipid nanoparticles enhance the efficacy of mRNA and protein subunit vaccines by inducing robust T follicular helper cell and humoral responses (2021) (126)
- A Multi-Targeting, Nucleoside-Modified mRNA Influenza Virus Vaccine Provides Broad Protection in Mice. (2020) (126)
- Both a precursor and a mature population of dendritic cells can bind HIV. However, only the mature population that expresses CD80 can pass infection to unstimulated CD4+ T cells. (1995) (125)
- mRNA transcript therapy (2015) (125)
- The efficiency of acute infection of CD4+ T cells is markedly enhanced in the setting of antigen-specific immune activation (1996) (120)
- Cutting Edge: Innate Immune System Discriminates between RNA Containing Bacterial versus Eukaryotic Structural Features That Prime for High-Level IL-12 Secretion by Dendritic Cells1 (2004) (118)
- Naturally occurring nucleoside modifications suppress the immunostimulatory activity of RNA: implication for therapeutic RNA development. (2007) (113)
- In vivo adenine base editing of PCSK9 in macaques reduces LDL cholesterol levels (2021) (112)
- HPLC purification of in vitro transcribed long RNA. (2013) (111)
- The Transcription Factor T-bet Resolves Memory B Cell Subsets with Distinct Tissue Distributions and Antibody Specificities in Mice and Humans. (2020) (110)
- In vitro transcription of long RNA containing modified nucleosides. (2013) (106)
- Chimeric spike mRNA vaccines protect against Sarbecovirus challenge in mice (2021) (95)
- IL-10 synergizes with multiple cytokines in enhancing HIV production in cells of monocytic lineage. (1995) (90)
- Antiviral Activities in Human Saliva (2011) (88)
- Exogenous siRNA Mediates Sequence-Independent Gene Suppression by Signaling through Toll-Like Receptor 3 (2004) (87)
- Reduced Cell Surface Expression of CCR5 in CCR5Δ32 Heterozygotes Is Mediated by Gene Dosage, Rather Than by Receptor Sequestration* (2002) (81)
- RNA based vaccines. (2002) (80)
- Nucleoside Modified mRNA Vaccines for Infectious Diseases. (2017) (79)
- Upregulation of the Phthiocerol Dimycocerosate Biosynthetic Pathway by Rifampin-Resistant, rpoB Mutant Mycobacterium tuberculosis (2012) (78)
- Early versus delayed antiretroviral therapy and cerebrospinal fluid fungal clearance in adults with HIV and cryptococcal meningitis. (2013) (76)
- Multifactorial nature of noncytolytic CD8+ T cell-mediated suppression of HIV replication: beta-chemokine-dependent and -independent effects. (1997) (69)
- Nucleoside-modified mRNA encoding HSV-2 glycoproteins C, D, and E prevents clinical and subclinical genital herpes (2019) (67)
- mRNA: Fulfilling the Promise of Gene Therapy. (2015) (67)
- A Membrane-proximal Basic Domain and Cysteine Cluster in the C-terminal Tail of CCR5 Constitute a Bipartite Motif Critical for Cell Surface Expression* (2001) (67)
- The in vitro induction of human immunodeficiency virus (HIV) replication in purified protein derivative-positive HIV-infected persons by recall antigen response to Mycobacterium tuberculosis is the result of a balance of the effects of endogenous interleukin-2 and proinflammatory and antiinflammator (1998) (66)
- gp340 expressed on human genital epithelia binds HIV-1 envelope protein and facilitates viral transmission. (2007) (66)
- Immunological profiling of tuberculosis-associated immune reconstitution inflammatory syndrome and non-immune reconstitution inflammatory syndrome death in HIV-infected adults with pulmonary tuberculosis starting antiretroviral therapy: a prospective observational cohort study. (2015) (65)
- Characterization of HIV-1 Nucleoside-Modified mRNA Vaccines in Rabbits and Rhesus Macaques (2019) (65)
- A molecular tweezer antagonizes seminal amyloids and HIV infection (2015) (65)
- Ionizable lipid nanoparticles for in utero mRNA delivery (2021) (65)
- PECAM‐1 directed re‐targeting of exogenous mRNA providing two orders of magnitude enhancement of vascular delivery and expression in lungs independent of apolipoprotein E‐mediated uptake (2018) (64)
- Scalable mRNA and siRNA Lipid Nanoparticle Production Using a Parallelized Microfluidic Device. (2021) (62)
- An ionizable lipid toolbox for RNA delivery (2021) (62)
- Respiratory mucosal immunity against SARS-CoV-2 following mRNA vaccination (2022) (60)
- Short Interfering RNA-Mediated Inhibition of Herpes Simplex Virus Type 1 Gene Expression and Function during Infection of Human Keratinocytes (2004) (59)
- Purification of mRNA Encoding Chimeric Antigen Receptor Is Critical for Generation of a Robust T-Cell Response (2019) (59)
- Ionization and structural properties of mRNA lipid nanoparticles influence expression in intramuscular and intravascular administration (2021) (59)
- In Vivo Identification of Langerhans and Related Dendritic Cells Infected with HIV-1 Subtype E in Vaginal Mucosa of Asymptomatic Patients (2001) (54)
- Interleukin-2 up-regulates expression of the human immunodeficiency virus fusion coreceptor CCR5 by CD4+ lymphocytes in vivo. (2000) (54)
- Identification of multiple and distinct CD8+ T cell suppressor activities: dichotomy between infected and uninfected individuals, evolution with progression of disease, and sensitivity to gamma irradiation. (1996) (53)
- Development of vaccines and antivirals for combating viral pandemics (2020) (48)
- gp340 Promotes Transcytosis of Human Immunodeficiency Virus Type 1 in Genital Tract-Derived Cell Lines and Primary Endocervical Tissue (2009) (47)
- Role of dendritic cells in immunopathogenesis of human immunodeficiency virus infection (1997) (47)
- Effect of Solar Particle Event Radiation and Hindlimb Suspension on Gastrointestinal Tract Bacterial Translocation and Immune Activation (2012) (47)
- Extracellular mRNA Induces Dendritic Cell Activation by Stimulating Tumor Necrosis Factor-α Secretion and Signaling through a Nucleotide Receptor* (2002) (44)
- Messenger RNA-Based Vaccines Against Infectious Diseases. (2020) (43)
- Anti-PfGARP activates programmed cell death of parasites and reduces severe malaria (2020) (41)
- Immune reconstitution. (2002) (40)
- Chronic inflammation with increased human immunodeficiency virus (HIV) RNA expression in the vaginal epithelium of HIV-infected Thai women. (2001) (40)
- mRNA vaccination induces tick resistance and prevents transmission of the Lyme disease agent (2021) (40)
- Sodium butyrate induced structural changes in HeLa cell chromatin. (1982) (39)
- Quantification of CD 4 , CCR 5 , and CXCR 4 levels on lymphocyte subsets , dendritic cells , and differentially conditioned monocyte-derived macrophages (1999) (39)
- Cytokine regulation of HIV replication induced by dendritic cell-CD4-positive T cell interactions. (1996) (38)
- Robust Reconstitution of Tuberculosis-Specific Polyfunctional CD4+ T-Cell Responses and Rising Systemic Interleukin 6 in Paradoxical Tuberculosis-Associated Immune Reconstitution Inflammatory Syndrome. (2016) (38)
- Repurposing Hsp104 to Antagonize Seminal Amyloid and Counter HIV Infection. (2015) (38)
- Highly efficient CD4+ T cell targeting and genetic recombination using engineered CD4+ cell-homing mRNA-LNPs (2021) (37)
- Hindlimb Suspension and SPE-Like Radiation Impairs Clearance of Bacterial Infections (2014) (37)
- The N-terminal SRCR-SID domain of gp-340 interacts with HIV type 1 gp120 sequences and inhibits viral infection. (2006) (36)
- Murine liver repair via transient activation of regenerative pathways in hepatocytes using lipid nanoparticle-complexed nucleoside-modified mRNA (2021) (36)
- gp340 Expressed on Human Genital Epithelia Binds HIV-1 Envelope Protein and Facilitates Viral Transmission1 (2007) (35)
- One-Component Multifunctional Sequence-Defined Ionizable Amphiphilic Janus Dendrimer Delivery Systems for mRNA. (2021) (34)
- A platelet-activating factor antagonist, RP 55778, inhibits cytokine-dependent induction of human immunodeficiency virus expression in chronically infected promonocytic cells. (1993) (32)
- Nonproliferating Bystander CD4+ T Cells Lacking Activation Markers Support HIV Replication During Immune Activation1 (2001) (31)
- Matrix Metalloproteinases in Tuberculosis-Immune Reconstitution Inflammatory Syndrome and Impaired Lung Function Among Advanced HIV/TB Co-infected Patients Initiating Antiretroviral Therapy (2015) (31)
- Early immunologic failure is associated with early mortality among advanced HIV-infected adults initiating antiretroviral therapy with active tuberculosis. (2013) (30)
- Vaccination with Messenger RNA: A Promising Alternative to DNA Vaccination. (2021) (27)
- Transfection of pseudouridine-modified mRNA encoding CPD-photolyase leads to repair of DNA damage in human keratinocytes: a new approach with future therapeutic potential. (2013) (27)
- Lipid nanoparticle encapsulated nucleoside-modified mRNA vaccines elicit polyfunctional HIV-1 antibodies comparable to proteins in nonhuman primates (2021) (27)
- HIV Envelope Binding by Macrophage-Expressed gp340 Promotes HIV-1 Infection1 (2008) (25)
- Chimeric spike mRNA vaccines protect against Sarbecovirus challenge in mice (2021) (24)
- Epigallocatechin-3-gallate rapidly remodels PAP85-120, SEM1(45-107), and SEM2(49-107) seminal amyloid fibrils (2015) (24)
- Human Cytomegalovirus Glycoprotein B Nucleoside-Modified mRNA Vaccine Elicits Antibody Responses with Greater Durability and Breadth than MF59-Adjuvanted gB Protein Immunization (2020) (23)
- A multivalent nucleoside-modified mRNA vaccine against all known influenza virus subtypes (2022) (23)
- Vaccine-delivered HIV envelope inhibits CD4(+) T-cell activation, a mechanism for poor HIV vaccine responses. (2007) (22)
- Evaluation of a Single-Dose Nucleoside-Modified Messenger RNA Vaccine Encoding Hendra Virus-Soluble Glycoprotein Against Lethal Nipah virus Challenge in Syrian Hamsters. (2019) (22)
- Messenger RNA expressing PfCSP induces functional, protective immune responses against malaria in mice (2021) (22)
- Targeted Delivery of mRNA with One-Component Ionizable Amphiphilic Janus Dendrimers. (2021) (21)
- An HSV-2 nucleoside-modified mRNA genital herpes vaccine containing glycoproteins gC, gD, and gE protects mice against HSV-1 genital lesions and latent infection (2020) (21)
- Development of mRNA manufacturing for vaccines and therapeutics: mRNA platform requirements and development of a scalable production process to support early phase clinical trials (2021) (21)
- Acute Biological Effects of Simulating the Whole-Body Radiation Dose Distribution from a Solar Particle Event Using a Porcine Model (2011) (20)
- Dual spike and nucleocapsid mRNA vaccination confer protection against SARS-CoV-2 Omicron and Delta variants in preclinical models (2022) (19)
- Nucleoside-modified mRNA vaccination partially overcomes maternal antibody inhibition of de novo immune responses in mice (2020) (19)
- Nucleofection induces transient eIF2α phosphorylation by GCN2 and PERK (2011) (18)
- Protection against herpes simplex virus type 2 infection in a neonatal murine model using a trivalent nucleoside-modified mRNA in lipid nanoparticle vaccine (2020) (18)
- Lipid nanoparticles enhance the efficacy of mRNA and protein subunit vaccines by inducing robust T follicular helper cell and humoral responses (2022) (18)
- Isoniazid clearance is impaired among human immunodeficiency virus/tuberculosis patients with high levels of immune activation (2017) (17)
- Synthesis of random copolymer based pH-responsive nanoparticles as drug carriers for cancer therapeutics† (2013) (16)
- Ionizing Radiation Selectively Reduces Skin Regulatory T Cells and Alters Immune Function (2014) (16)
- Periluminal Distribution of HIV-Binding Target Cells and Gp340 in the Oral, Cervical and Sigmoid/Rectal Mucosae: A Mapping Study (2015) (16)
- Effect of Solar Particle Event Radiation on Gastrointestinal Tract Bacterial Translocation and Immune Activation (2011) (16)
- Common Variation in NLRP3 Is Associated With Early Death and Elevated Inflammasome Biomarkers Among Advanced HIV/TB Co-infected Patients in Botswana (2018) (16)
- Effect of GB virus C viremia on HIV acquisition and HIV set-point (2005) (16)
- Breadth of SARS-CoV-2 Neutralization and Protection Induced by a Nanoparticle Vaccine (2022) (15)
- HIV Envelope Suppresses CD4+ T Cell Activation Independent of T Regulatory Cells1 (2008) (15)
- Fucosylated lactosamines participate in adhesion of HIV-1 envelope glycoprotein to dendritic cells (2003) (15)
- The Unexpected Importance of the Primary Structure of the Hydrophobic Part of One-Component Ionizable Amphiphilic Janus Dendrimers in Targeted mRNA Delivery Activity. (2022) (15)
- Added to pre-existing inflammation, mRNA-lipid nanoparticles induce inflammation exacerbation (IE) (2021) (14)
- The Chronically Infected Promonocytic Cell Line U1: A Model of HIV Expression Regulated by Cytokines (1993) (14)
- Short Communication: The Role of Dendritic Cells in the Infection of CD4+ T Cells with the Human Immunodeficiency Virus: Use of Dendritic Cells from Individuals Homozygous for the Δ32CCR5 Allele as a Model (1998) (14)
- Nucleoside-modified VEGFC mRNA induces organ-specific lymphatic growth and reverses experimental lymphedema (2021) (14)
- Pyrazinamide clearance is impaired among HIV/tuberculosis patients with high levels of systemic immune activation (2017) (13)
- Vaccine innovations for emerging infectious diseases—a symposium report (2020) (13)
- Increased surface expression of HIV-1 envelope is associated with improved antibody response in vaccinia prime/protein boost immunization (2018) (13)
- Broad-Spectrum Antibiotic or G-CSF as Potential Countermeasures for Impaired Control of Bacterial Infection Associated with an SPE Exposure during Spaceflight (2015) (13)
- Author Correction: Lipid nanoparticle encapsulated nucleoside-modified mRNA vaccines elicit polyfunctional HIV-1 antibodies comparable to proteins in nonhuman primates (2020) (13)
- Lipid nanoparticle chemistry determines how nucleoside base modifications alter mRNA delivery (2021) (13)
- Dendritic cells express and use multiple HIV coreceptors. (1997) (13)
- A Common NLRC4 Gene Variant Associates With Inflammation and Pulmonary Function in Human Immunodeficiency Virus and Tuberculosis. (2019) (13)
- Lipid-nanoparticle encapsulated mRNA vaccines induce protective memory CD8 T cells against a lethal viral infection. (2021) (11)
- Vaccinating HIV patients: focus on human papillomavirus and herpes zoster vaccines. (2013) (10)
- Rational design of anti-inflammatory lipid nanoparticles for mRNA delivery. (2022) (9)
- Lung Injury on Antiretroviral Therapy in Adults With Human Immunodeficiency Virus/Tuberculosis (2019) (9)
- Debunking mRNA Vaccine Misconceptions—An Overview for Medical Professionals (2021) (9)
- mRNA-encoded HIV-1 Env trimer ferritin nanoparticles induce monoclonal antibodies that neutralize heterologous HIV-1 isolates in mice (2022) (8)
- Amniotic fluid stabilized lipid nanoparticles for in utero intra-amniotic mRNA delivery. (2021) (8)
- Markers of gut dysfunction do not explain low rifampicin bioavailability in HIV-associated TB (2017) (8)
- Trivalent nucleoside-modified mRNA vaccine yields durable memory B cell protection against genital herpes in preclinical models. (2021) (8)
- Identification of Cyclobutane Pyrimidine Dimer-Responsive Genes Using UVB-Irradiated Human Keratinocytes Transfected with In Vitro-Synthesized Photolyase mRNA (2015) (7)
- Declines in Lung Function After Antiretroviral Therapy Initiation in Adults With Human Immunodeficiency Virus and Tuberculosis: A Potential Manifestation of Respiratory Immune Reconstitution Inflammatory Syndrome (2019) (7)
- SARS-CoV-2 vaccination induces neutralizing antibodies against pandemic and pre-emergent SARS-related coronaviruses in monkeys (2021) (7)
- Safe and Effective In Vivo Targeting and Gene Editing in Hematopoietic Stem Cells: Strategies for Accelerating Development National Institutes of Health/Bill & Melinda Gates Foundation Expert Scientific Roundtable Webinar Meeting. (2021) (7)
- Rational Design of Bisphosphonate Lipid-like Materials for mRNA Delivery to the Bone Microenvironment. (2022) (7)
- Induction of HIV‐specific T and B cell responses with a replicating and conditionally infectious lentiviral vaccine (2008) (6)
- Author Correction: mRNA vaccines for infectious diseases: principles, delivery and clinical translation (2021) (6)
- Tick immunity using mRNA, DNA and protein-based Salp14 delivery strategies. (2021) (6)
- Lung injury on antiretroviral therapy in adults with HIV/TB. (2019) (6)
- Hydroxycholesterol substitution in Ionizable lipid nanoparticles for mRNA delivery to T cells. (2022) (5)
- Optimizing ethambutol dosing among HIV/tuberculosis co-infected patients: a population pharmacokinetic modelling and simulation study. (2019) (5)
- Transient yet Robust Expression of Proteins in the Mouse Liver via Intravenous Injection of Lipid Nanoparticle-encapsulated Nucleoside-modified mRNA. (2021) (5)
- Measuring the Adjuvant Activity of RNA Vaccines. (2017) (5)
- Nucleoside-Modified mRNA Vaccines Protect IFNAR–/– Mice against Crimean-Congo Hemorrhagic Fever Virus Infection (2021) (5)
- Human Mesenchymal Stem Cells as a Carrier for a Cell-Mediated Drug Delivery (2022) (4)
- Ability of nucleoside-modified mRNA to encode HIV-1 envelope trimer nanoparticles (2021) (4)
- Acute effects of solar particle event radiation (2014) (4)
- Elevated Pre–Antiretroviral Therapy CD39+CD8+ T Cell Frequency Is Associated With Early Mortality in Advanced Human Immunodeficiency Virus/Tuberculosis Co-infection (2017) (4)
- Novel lipid nanoparticle provides potent SARS-CoV-2 mRNA vaccine at low dose with low local reactogenicity, high thermostability and limited systemic biodistribution (2021) (3)
- mRNA-LNP expressing PfCSP and Pfs25 vaccine candidates targeting infection and transmission of Plasmodium falciparum (2022) (3)
- The role of dendritic cells in the infection of CD4+ T cells with the human immunodeficiency virus: use of dendritic cells from individuals homozygous for the delta32CCR5 allele as a model. (1998) (3)
- Ionizable lipid nanoparticles deliver mRNA to pancreatic β cells via macrophage-mediated gene transfer (2023) (3)
- Antibodies to Crucial Epitopes on HSV-2 Glycoprotein D as a Guide to Dosing an mRNA Genital Herpes Vaccine (2022) (3)
- Nucleoside-modified mRNA immunization elicits influenza virus hemagglutinin stalk-specific antibodies (2018) (3)
- Modified E2 Glycoprotein of Hepatitis C Virus Enhances Proinflammatory Cytokines and Protective Immune Response (2022) (2)
- Safe and Effective In Vivo Targeting and Gene Editing in Hematopoietic Stem Cells: Strategies for Accelerating Development (2021) (2)
- Ionizable Lipid Nanoparticles for In Vivo mRNA Delivery to the Placenta during Pregnancy. (2023) (2)
- Ligand-tethered lipid nanoparticles for targeted RNA delivery to treat liver fibrosis (2023) (2)
- mRNA vaccine with unmodified uridine induces robust type I interferon-dependent anti-tumor immunity in a melanoma model (2022) (2)
- SARS-CoV-2 evolution and immune escape in immunocompromised patients treated with exogenous antibodies (2022) (2)
- Author Correction: Murine liver repair via transient activation of regenerative pathways in hepatocytes using lipid nanoparticle-complexed nucleoside-modified mRNA (2021) (2)
- Lipid nanoparticles (LNP) induce activation and maturation of antigen presenting cells in young and aged individuals (2022) (2)
- Chapter 7 Nucleoside modifications of in vitro transcribed mRNA to reduce immunogenicity and improve translation of prophylactic and therapeutic antigens (2022) (2)
- HCMV glycoprotein B nucleoside-modified mRNA vaccine elicits antibody responses with greater durability and breadth than MF59-adjuvanted gB protein immunization (2019) (2)
- Combinatorial mRNA vaccination enhances protection against SARS-CoV-2 delta variant (2021) (2)
- Modified E2 glycoprotein of hepatitis C virus enhances pro-inflammatory cytokines and protective immune response in mice (2022) (1)
- Lipid nanoparticles delivering constitutively active STING mRNA as a novel anti-cancer therapeutic approach (2022) (1)
- Immunogenicity and Protective Efficacy of a SARS-CoV-2 mRNA Vaccine Encoding Secreted Non-Stabilized Spike Protein in Mice (2022) (1)
- Properdin is a pattern recognition molecule for viral double-stranded RNA and contributes to host antiviral innate immune response (2010) (1)
- mRNA-based vaccines against SARS-CoV-2 do not stimulate interferon stimulatory gene expression in individuals affected by Aicardi Goutières Syndrome (2022) (1)
- Lipid Nanoparticle Composition Drives mRNA Delivery to the Placenta (2022) (1)
- An electrochemiluminescence assay for gp340 (DMBT1). (2013) (1)
- Exploring in vitro expression and immune potency in mice using mRNA encoding the Plasmodium falciparum malaria antigen, CelTOS (2022) (1)
- SIV antigen immunization induces transient antigen-specific T cell responses and selectively activates viral replication in draining lymph nodes in retroviral suppressed rhesus macaques (2011) (1)
- Targeted nanocarriers coopting pulmonary leukocytes for drug delivery to the injured brain (2022) (1)
- Nucleoside-Modified mRNA-Based Influenza Vaccines Circumvent Problems Associated with H3N2 Vaccine Strain Egg Adaptation (2022) (1)
- Breadth of SARS-CoV-2 neutralization and protection induced by a nanoparticle vaccine (2022) (0)
- In Vivo Modification of Hematopoietic Stem Cells By Targeted Lipid Nanoparticles Encapsulating mRNA (2022) (0)
- Anti-PfGARP activates programmed cell death of parasites and reduces severe malaria (2020) (0)
- Replication During Immune Activation Lacking Activation Markers Support HIV T Cells + Nonproliferating Bystander CD4 (2001) (0)
- Use of Nucleoside Modified mRNA Encoding Regenerative Factors Encapsulated with Lipid Nanoparticles to Alleviate Acute and Chronic Murine Liver Diseases (2022) (0)
- Title A molecular tweezer antagonizes seminal amyloids and HIV infection (2015) (0)
- Bacterial Single-Stranded RNA and Its Structural Mimics Activate High-Level Interleukin-12 Secretion by Human Dendritic Cells (2004) (0)
- Multivalent Human Cytomegalovirus Glycoprotein B Nucleoside-Modified mRNA Vaccines Demonstrate a Greater Breadth in T cell but not Antibody Responses (2022) (0)
- Messenger RNA expressing PfCSP induces functional, protective immune responses against malaria in mice (2021) (0)
- Impacts of Nucleoside Modi.cation on RNAMediated Activation of Toll-Like Receptors (2008) (0)
- Author response: A molecular tweezer antagonizes seminal amyloids and HIV infection (2015) (0)
- Abstract P768: Vascular Cellular Adhesion Molecule Targeting for the Treatment of Acute Neurovascular Inflammation (2021) (0)
- Replication During Immune Activation Lacking Activation Markers Support HIV Nonproliferating Bystander CD4+ T Cells (2013) (0)
- Author Correction: mRNA vaccines for infectious diseases: principles, delivery and clinical translation (2021) (0)
- Evaluation of mRNA-LNP and adjuvanted protein SARS-CoV-2 vaccines in a maternal antibody mouse model (2023) (0)
- VEGFA mRNA-LNP promotes biliary epithelial cell-to-hepatocyte conversion in acute and chronic liver diseases and reverses steatosis and fibrosis (2023) (0)
- RNA vaccines: past, present & future (2022) (0)
- Preventing neonatal herpes: Protection after maternal mRNA-lipid nanoparticle vaccination equals or exceeds that from prior maternal genital infection in murine models (2022) (0)
- Lipid nanoparticle encapsulated nucleoside-modified mRNA vaccines elicit polyfunctional HIV-1 antibodies comparable to proteins in nonhuman primates (2021) (0)
- Direct Delivery of mRNA-Loaded Lipid Nanoparticles to the Hematopoietic Stem Cell Niche (2022) (0)
- Nucleoside‐modified mRNA vaccines yield robust blocking antibody responses against major house dust mite allergens (2022) (0)
- Lipid nanoparticles (LNP) induce activation and maturation of antigen presenting cells in young and aged individuals (2023) (0)
- The Eff iciency o f Acute Infect ion o f CD 4 + T cells Is Markedly Enhanced in the Sett ing o f Ant igen (2003) (0)
- Immunogenicity and protective efficacy of SARS-CoV-2 mRNA vaccine encoding secreted non-stabilized spike in female mice (2023) (0)
- Development of a nucleoside-modified mRNA vaccine against clade 2.3.4.4b H5 highly pathogenic avian influenza virus (2023) (0)
- Safety and immunogenicity of a prefusion non-stabilized spike protein mRNA COVID-19 vaccine: a phase I trial (2022) (0)
- Erratum: Transfection of pseudouridine-modified mRNA encoding CPD-photolyase leads to repair of DNA damage in human keratinocytes: A new approach with future therapeutic potential (Journal of Photochemistry and Photobiology B: Biology (2013) 129 (93-99)) (2014) (0)
- This information is current as Dendritic Cells That Prime for High-Level IL-12 Secretion by Bacterial versus Eukaryotic Structural Features Discriminates between RNA Containing Cutting Edge : Innate Immune System (2004) (0)
- Breast tumors interfere with endothelial TRAIL at the premetastatic niche to promote cancer cell seeding (2023) (0)
- Vaccine induction of CD4-mimicking broadly neutralizing antibody precursors in macaques (2023) (0)
- Lipid Nanoparticles Delivering Constitutively Active STING mRNA to Stimulate Antitumor Immunity (2022) (0)
- A Phase1 Results of a Non-Stabilized Spike-Encoding mRNA Vaccine in Adults (2022) (0)
- The impact of lipid nanoparticles (LNP) on anti-viral pathways and immune function in aged individuals (2022) (0)
- Receptors Used as Coreceptors for HIV Entry Dendritic Cells Express Multiple Chemokine (1998) (0)
- Molecular Design Principles to Target mRNA Delivery With One-Component Ionizable Amphiphilic Janus Dendrimers Derived From Plant Phenolic Acids (2022) (0)
- Author Correction: Lipid nanoparticle encapsulated nucleoside-modified mRNA vaccines elicit polyfunctional HIV-1 antibodies comparable to proteins in nonhuman primates (2021) (0)
- SARS-CoV-2 mRNA-based vaccines in the Aicardi Goutières Syndrome (2022) (0)
- Mutation-Guided Vaccine Design: A Strategy for Developing Boosting Immunogens for HIV Broadly Neutralizing Antibody Induction (2022) (0)
- Cytokines and cytokine antagonists control the replication of the human immunodeficiency virus (HIV) in vitro (1994) (0)
- Hepatitis C virus E1 and modified E2 delivered from an mRNA vaccine induces protective immunity (2023) (0)
- 2772. HCMV gB Ectodomain Subunit and gB mRNA Vaccines Reduce AD-3 Immunodominance and Elicit More Durable Antibody Responses Than gB/MF59 Immunization (2019) (0)
- The Regulation of Nucleic Acid Vaccine Responses by the Microbiome (2023) (0)
- Restoration of Motor Function through Delayed Intraspinal Delivery of Human IL-10-Encoding Nucleoside-Modified mRNA after Spinal Cord Injury (2023) (0)
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