David T. Denhardt

David T. Denhardt's AcademicInfluence.com Rankings

David T. Denhardt

Biology

#4763

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#7066

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Biochemistry

#509

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#597

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Biology

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David T. Denhardt's Published Works

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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

A membrane-filter technique for the detection of complementary DNA. (1966) (3458)
Eta-1 (osteopontin): an early component of type-1 (cell-mediated) immunity. (2000) (1113)
Osteopontin: a protein with diverse functions (1993) (1100)
Osteopontin as a means to cope with environmental insults: regulation of inflammation, tissue remodeling, and cell survival. (2001) (1074)
The Influence of the Proinflammatory Cytokine, Osteopontin, on Autoimmune Demyelinating Disease (2001) (805)
Osteopontin, a key component of the hematopoietic stem cell niche and regulator of primitive hematopoietic progenitor cells. (2005) (779)
Osteopontin is elevated during neointima formation in rat arteries and is a novel component of human atherosclerotic plaques. (1993) (687)
Osteopontin: role in immune regulation and stress responses. (2011) (607)
Signal-transducing protein phosphorylation cascades mediated by Ras/Rho proteins in the mammalian cell: the potential for multiplex signalling. (1996) (525)
Antisense RNA-induced reduction in murine TIMP levels confers oncogenicity on Swiss 3T3 cells. (1989) (459)
Identification of a DNA sequence responsible for binding of the 1,25-dihydroxyvitamin D3 receptor and 1,25-dihydroxyvitamin D3 enhancement of mouse secreted phosphoprotein 1 (SPP-1 or osteopontin) gene expression. (1990) (436)
Mice Lacking Osteopontin Show Normal Development and Bone Structure but Display Altered Osteoclast Formation In Vitro (1998) (435)
Osteopontin expression and function: Role in bone remodeling (1998) (413)
Role of osteopontin in cellular signaling and toxicant injury. (2001) (345)
Osteopontin-deficient mice are resistant to ovariectomy-induced bone resorption. (1999) (330)
Tissue inhibitor of metalloproteinases (TIMP, aka EPA): structure, control of expression and biological functions. (1993) (285)
Osteopontin deficiency produces osteoclast dysfunction due to reduced CD44 surface expression. (2003) (249)
Control of osteopontin signaling and function by post‐translational phosphorylation and protein folding (2007) (248)
Osteopontin expression in angiotensin II-induced tubulointerstitial nephritis. (1994) (245)
Osteopontin, a transformation-associated cell adhesion phosphoprotein, is induced by 12-O-tetradecanoylphorbol 13-acetate in mouse epidermis. (1989) (245)
Vectors: A Survey of Molecular Cloning Vectors and Their Uses (1987) (220)
Osteopontin as a mediator of NKT cell function in T cell-mediated liver diseases. (2004) (208)
Osteopontin deficiency protects joints against destruction in anti-type II collagen antibody-induced arthritis in mice (2002) (207)
Unloading Induces Osteoblastic Cell Suppression and Osteoclastic Cell Activation to Lead to Bone Loss via Sympathetic Nervous System* (2005) (196)
Osteopontin Deficiency Attenuates Atherosclerosis in Female Apolipoprotein E–Deficient Mice (2003) (194)
Enhancement of Osteoclastic Bone Resorption and Suppression of Osteoblastic Bone Formation in Response to Reduced Mechanical Stress Do Not Occur in the Absence of Osteopontin (2001) (191)
An Osteopontin‐Integrin Interaction Plays a Critical Role in Directing Adipogenesis and Osteogenesis by Mesenchymal Stem Cells (2014) (188)
Osteopontin inhibits induction of nitric oxide synthase gene expression by inflammatory mediators in mouse kidney epithelial cells. (1994) (186)
The rep mutation. IV. Slower movement of replication forks in Escherichia coli rep strains. (1975) (181)
Thrombin-cleaved osteopontin regulates hemopoietic stem and progenitor cell functions through interactions with alpha9beta1 and alpha4beta1 integrins. (2009) (179)
The single-stranded DNA phages. (1975) (179)
Osteopontin Expression in Osteoblasts and Osteocytes During Bone Formation Under Mechanical Stress in the Calvarial Suture In Vivo (2003) (178)
The murine gene encoding secreted phosphoprotein 1 (osteopontin): promoter structure, activity, and induction in vivo by estrogen and progesterone. (1991) (176)
Role of Osteopontin in Cardiac Fibrosis and Remodeling in Angiotensin II–Induced Cardiac Hypertrophy (2004) (174)
Osteopontin Function in Pathology: Lessons from Osteopontin-Deficient Mice (1999) (173)
Osteopontin modulates CD44‐dependent chemotaxis of peritoneal macrophages through G‐protein‐coupled receptors: Evidence of a role for an intracellular form of osteopontin (2004) (173)
Matrix metalloproteinases and tissue inhibitor of metalloproteinases: a review of their role in tumorigenesis and tissue invasion. (1989) (171)
Gene expression during the mammalian cell cycle. (1986) (157)
Reduced malignancy of ras-transformed NIH 3T3 cells expressing antisense osteopontin RNA. (1994) (157)
Colocalization of Intracellular Osteopontin With CD44 Is Associated With Migration, Cell Fusion, and Resorption in Osteoclasts (2002) (156)
Osteopontin facilitates angiogenesis, accumulation of osteoclasts, and resorption in ectopic bone. (2001) (155)
Cysteine proteinase cathepsin L expression correlates closely with the metastatic potential of H-ras-transformed murine fibroblasts. (1987) (154)
A growth-responsive gene (16C8) in normal mouse fibroblasts homologous to a human collagenase inhibitor with erythroid-potentiating activity: evidence for inducible and constitutive transcripts. (1986) (150)
Osteopontin inhibits nitric oxide production and cytotoxicity by activated RAW264.7 macrophages (1996) (138)
The ERR-1 orphan receptor is a transcriptional activator expressed during bone development. (1997) (137)
Secreted phosphoprotein mrna is induced during multi‐stage carcinogenesis in mouse skin and correlates with the metastatic potential of murine fibroblasts (1990) (131)
Cell Type-specific Post-translational Modifications of Mouse Osteopontin Are Associated with Different Adhesive Properties* (2007) (131)
Molecular cloning of a tumor promoter‐inducible mRNA found in JB6 mouse epidermal cells: Induction is stable at high, but not at low, cell densities (1987) (129)
The process of infection with bacteriophage φX174: III. Phage maturation and lysis after synchronized infection† (1965) (127)
Expression genomics of cervical cancer: molecular classification and prediction of radiotherapy response by DNA microarray. (2003) (127)
Increased thalamic neurodegeneration following ischaemic cortical stroke in osteopontin-deficient mice. (2006) (125)
Identification of the major phosphoprotein secreted by many rodent cell lines as 2ar/osteopontin: enhanced expression in H-ras-transformed 3T3 cells. (1988) (117)
Response to Comment on "The Influence of the Proinflammatory Cytokine, Osteopontin, on Autoimmune Demyelinating Disease" (2003) (117)
Soluble osteopontin inhibits apoptosis of adherent endothelial cells deprived of growth factors * (2002) (117)
An Osteopontin–NADPH Oxidase Signaling Cascade Promotes Pro–Matrix Metalloproteinase 9 Activation in Aortic Mesenchymal Cells (2006) (115)
Osteopontin‐Induced Modifications of Cellular Functions a (1995) (114)
Osteopontin expression correlates with melanoma invasion. (2005) (113)
Transcriptional regulation of two serum-induced RNAs in mouse fibroblasts: equivalence of one species to B2 repetitive elements (1985) (112)
Suppression by cathepsin L inhibitors of the invasion of amnion membranes by murine cancer cells. (1989) (109)
Transcriptional regulation of osteopontin and the metastatic phenotype: Evidence for a Ras-activated enhancer in the human OPN promoter (2004) (107)
Osteopontin Deficiency Reduces Experimental Tumor Cell Metastasis to Bone and Soft Tissues (2001) (107)
Induction of expression of osteopontin (OPN; secreted phosphoprotein) in metastatic, ras-transformed NIH 3T3 cells. (1992) (106)
Parathyroid Hormone-induced Bone Resorption Does Not Occur in the Absence of Osteopontin* (2001) (106)
Resistance to Unloading‐Induced Three‐Dimensional Bone Loss in Osteopontin‐Deficient Mice (2002) (103)
Increased expression of cathepsins L and B and decreased activity of their inhibitors in metastatic, ras‐transformed NIH 3T3 cells (1992) (102)
Osteopontin is required for full expression of the transformed phenotype by the ras oncogene (2000) (100)
Reduced tolerance to acute renal ischemia in mice with a targeted disruption of the osteopontin gene. (1999) (99)
Identification of a ras-activated enhancer in the mouse osteopontin promoter and its interaction with a putative ETS-related transcription factor whose activity correlates with the metastatic potential of the cell (1995) (96)
Osteopontin-Deficient Mice Exhibit Less Inflammation, Greater Tissue Damage, and Impaired Locomotor Recovery from Spinal Cord Injury Compared with Wild-Type Controls (2007) (95)
Heterogeneity of osteopontin expression among nephrons in mouse kidneys and enhanced expression in sclerotic glomeruli. (1993) (91)
Temporal expression of tissue inhibitors of metalloproteinases in mouse reproductive tissues during gestation (1993) (89)
Sympathetic control of bone mass regulated by osteopontin (2011) (82)
Rho-dependent Rho Kinase Activation Increases CD44 Surface Expression and Bone Resorption in Osteoclasts* (2003) (81)
Osteopontin: an intrinsic inhibitor of inflammation in cartilage. (2001) (77)
The process of infection with bacteriophage phi-X174. IV. Replication of the viral DNA in a synchronized infection. (1965) (76)
THE ABORTIVE REPLICATION OF PhiX174 DNA IN A RECOMBINATION-DEFICIENT MUTANT OF Escherichia coli. (1967) (76)
Age and development‐related changes in osteopontin and nitric oxide synthase mRNA levels in human kidney proximal tubule epithelial cells: Contrasting responses to hypoxia and reoxygenation (1994) (75)
A study of mitochondrial and nuclear transcription with cloned cDNA probes. Changes in the relative abundance of mitochondrial transcripts after stimulation of quiescent mouse fibroblasts. (1985) (74)
Osteopontin Facilitates Bone Resorption, Decreasing Bone Mineral Crystallinity and Content During Calcium Deficiency (2003) (74)
The mechanism of replication of phi X174 single-stranded DNA. 3. An enzymic study of the structure of the replicative form II DNA. (1971) (71)
Tissue inhibitor of metalloproteinase-1 stimulates proliferation of human cancer cells by inhibiting a metalloproteinase (2004) (70)
Accelerated development of aging-associated and instability-induced osteoarthritis in osteopontin-deficient mice. (2009) (70)
Osteopontin regulates hindlimb-unloading-induced lymphoid organ atrophy and weight loss by modulating corticosteroid production (2007) (70)
The rep Mutation III. Altered Structure of the Replicating Escherichia coli Chromosome (1974) (68)
Regulation of the mRNA for monocyte-derived neutrophil-activating peptide in differentiating HL60 promyelocytes (1989) (67)
Osteopontin deficiency protects against aldosterone-induced inflammation, oxidative stress, and interstitial fibrosis in the kidney. (2011) (67)
Increased expression of the remodeling- and tumorigenic-associated factor osteopontin in pyramidal neurons of the Alzheimer's disease brain. (2007) (66)
Studies on phiX174 proteins. I. Phage-specific proteins synthesized after infection of Escherichia coli. (1969) (66)
Osteopontin deficiency and aging on nanomechanics of mouse bone. (2007) (64)
Identification of a serum-inducible messenger RNA (5B10) as the mouse homologue of calcyclin: tissue distribution and expression in metastatic, ras-transformed NIH 3T3 cells. (1990) (62)
Sensitivity of superhelical DNA to a single-strand specific endonuclease. (1973) (58)
Antagonistic effects of transforming growth factor-beta on vitamin D3 enhancement of osteocalcin and osteopontin transcription: reduced interactions of vitamin D receptor/retinoid X receptor complexes with vitamin E response elements. (1996) (58)
Close relationship of the major excreted protein of transformed murine fibroblasts to thiol-dependent cathepsins. (1986) (57)
Osteopontin is required for mechanical stress-dependent signals to bone marrow cells. (2007) (57)
Oncogene-initiated aberrant signaling engenders the metastatic phenotype: synergistic transcription factor interactions are targets for cancer therapy. (1996) (54)
Corneal wound healing in an osteopontin-deficient mouse. (2008) (53)
Mechanism of Action of Antisense RNA. Sometime Inhibition of Transcription, Processing, Transport, or Translation a (1992) (52)
Differential effects of osteopontin on the cytotoxic activity of macrophages from young and old mice (1996) (51)
Osteopontin (OPN) may facilitate metastasis by protecting cells from macrophage NO-mediated cytotoxicity: evidence from cell lines down-regulated for OPN expression by a targeted ribozyme (1995) (50)
Serum osteopontin, an enhancer of tumor metastasis to bone, promotes B16 melanoma cell migration (2007) (50)
Expression of attachment proteins during cementogenesis. (1990) (50)
Regulation of Collagenase-3 and Osteocalcin Gene Expression by Collagen and Osteopontin in Differentiating MC3T3-E1 Cells* (2002) (50)
Deficiency of MMP17/MT4-MMP proteolytic activity predisposes to aortic aneurysm in mice. (2015) (49)
Characterization of a cDNA clone encoding murine mitogen-regulated protein: regulation of mRNA levels in mortal and immortal cell lines (1985) (49)
Prenatal Detection of Embryo Resorption in Osteopontin-Deficient Mice Using Serial Noninvasive Magnetic Resonance Microscopy (2004) (48)
Stimulation of Mouse Osteopontin Promoter by v-Src Is Mediated by a CCAAT Box-binding Factor* (1996) (48)
Comparison of the effect of ultraviolet radiation and ethidium bromide intercalation on the conformation of superhelical phiX174 replicative form DNA. (1973) (48)
The rep mutation. II. Its effect on Escherichia coli and on the replication of bacteriophage phi X174. (1972) (47)
Osteopontin deficiency induces parathyroid hormone enhancement of cortical bone formation. (2003) (47)
p53 mutations in spontaneously immortalized 3T12 but not 3T3 mouse embryo cells. (1992) (47)
Effect of cyanide and carbon monoxide on the replication of bacterial DNA in vivo. (1968) (46)
The Cytokine Osteopontin Modulates the Severity of Rotavirus Diarrhea (2005) (46)
Mechanisms of cellular invasiveness: a comparison of amnion invasion in vitro and metastatic behavior in vivo. (1989) (45)
Osteopontin is associated with nuclear factor kappaB gene expression during tail-suspension-induced bone loss. (2006) (45)
OPN deficiency suppresses appearance of odontoclastic cells and resorption of the tooth root induced by experimental force application (2008) (44)
Escherichia coli rep gene: sequence of the gene, the encoded helicase, and its homology with uvrD. (1987) (42)
Involvement of Osteopontin in the Matrix-Degrading and Proangiogenic Changes Mediated by Nicotine in Pancreatic Cancer Cells (2010) (41)
Osteopontin Negatively Regulates Parathyroid Hormone Receptor Signaling in Osteoblasts* (2008) (40)
Induction of osteopontin expression by nicotine and cigarette smoke in the pancreas and pancreatic ductal adenocarcinoma cells (2009) (39)
Osteopontin regulates development and function of invariant natural killer T cells (2008) (38)
Expression of a prometastatic splice variant of osteopontin, OPNC, in human pancreatic ductal adenocarcinoma. (2009) (38)
The process of infection with bacteriophage phi-XD174. VI. Inactivation of infected complexes by ultraviolet irradiation. (1965) (37)
Developmental expression of cathepsin L and c‐rasHa in the mouse placenta (1991) (37)
An analysis of the clone size distribution of ΦX174 mutants and recombinants (1966) (36)
The role of osteopontin in tendon tissue remodeling after denervation-induced mechanical stress deprivation. (2007) (35)
The mechanism of replication of phi X174 single-stranded DNA. II. The role of viral proteins. (1971) (35)
Effect of stress on human biology: Epigenetics, adaptation, inheritance, and social significance (2018) (34)
Inhibition of synthesis of phiX174 DNA in a mutant host thermosensitive for DNA synthesis. (1968) (33)
Osteopontin expression detected in adult cochleæ and inner ear fluids (1995) (33)
Adhesion Molecules in Renal Disease (1999) (33)
The Process of Infection with Bacteriophage φX174: V. Inactivation of the Phage-Bacterium Complex by Decay of ^(32)P incorporated in the Infecting Particle (1965) (32)
The Escherichia coli rep mutation. X. Consequences of increased and decreased Rep protein levels (1987) (32)
Osteopontin deficiency impairs wear debris-induced osteolysis via regulation of cytokine secretion from murine macrophages. (2010) (31)
Characterization of a mouse mitogen-regulated protein/proliferin gene and its promoter: a member of the growth hormone/prolactin gene superfamily. (1989) (31)
Formation of ribosylthymine in Escherichia coli. Studies on pulse labeling with thymine and thymidine. (1969) (31)
Osteopontin affects the persistence of beta-glucan-induced hepatic granuloma formation and tissue injury through two distinct mechanisms. (2004) (31)
A human promyelocyte mRNA transiently induced by TPA is homologous to yeast IPP isomerase. (1994) (31)
Loss of osteopontin perturbs the epithelial-mesenchymal transition in an injured mouse lens epithelium (2007) (31)
Cell cycle-regulated and proliferation stimulus-responsive genes. (1991) (31)
Helix-loop-helix-type transcription factor (HES-1) is expressed in osteoblastic cells, suppressed by 1,25(OH)2 vitamin D3, and modulates 1,25(OH)2 vitamin D3 enhancement of osteopontin gene expression. (1997) (30)
Role of Osteopontin in Murine Lyme Arthritis and Host Defense against Borrelia burgdorferi (2002) (29)
Mechanism of Replication of φX174 Single-Stranded DNA IX. Requirement for the Escherichia coli dnaG Protein (1974) (29)
The Isometric Single-Stranded DNA Phages (1977) (28)
Acetaminophen Attenuates Doxorubicin-Induced Cardiac Fibrosis Via Osteopontin and GATA4 Regulation: Reduction of Oxidant Levels (2013) (28)
Modulation of translation by the 5' leader sequence of the mRNA encoding murine tissue inhibitor of metalloproteinases. (1990) (27)
Physical map and strand polarity of specific fragments of adenovirus-associated virus DNA produced by endonuclease R-EcoRI (1975) (27)
Osteopontin deficiency suppresses high phosphate load-induced bone loss via specific modulation of osteoclasts. (2006) (27)
Osteopontin Traffic in Hypoxic Renal Epithelial Cells (2003) (27)
Characterization of the complex between SV40 large T antigen and the 53K host protein in transformed mouse cells. (1980) (26)
Osteopontin Participates in Th1-Mediated Host Resistance against Nonlethal Malaria Parasite Plasmodium chabaudi chabaudi Infection in Mice (2006) (26)
On the use of anti-sense RNA: down-regulation of mRNA encoding a metalloproteinase inhibitor. (1987) (25)
Lack of in vivo function of osteopontin in experimental anti-GBM nephritis. (2000) (25)
Cloning and characterization of murine carnitine acetyltransferase: evidence for a requirement during cell cycle progression. (1997) (25)
The mechanism of replication of øX174 DNA (1975) (24)
Evidence for two pathways of protein kinase C induction of 2AR expression: Correlation with mitogenesis (1989) (23)
Establishment and characterization of bone marrow stromal cell lines that support osteoclastogenesis. (1995) (23)
Aprt/Opn double knockout mice: osteopontin is a modifier of kidney stone disease severity. (2005) (23)
Evidence for the presence of ribonucleotides at the 5' termini of some DNA molecules isolated from Escherichia coli polAex2. (1977) (23)
Regulation of no synthesis induced by inflammatory mediators in RAW264.7 cells: collagen prevents inhibition by osteopontin. (2000) (22)
Ultraviolet light irradiation of PM2 superhelical DNA. (1977) (22)
Characterization of osteopontin expression and function after status epilepticus (2008) (22)
Regulation of the expression of mitogen-regulated protein (MRP; proliferin) and cathepsin L in cultured cells and in the murine placenta (1991) (21)
Osteopontin: Role in Cell Signalling and Adhesion (1995) (21)
p21ras and protein kinase C function in distinct and interdependent signaling pathways in C3H 10T1/2 fibroblasts (1993) (21)
Osteopontin expression and function within the dorsal root ganglion (2007) (21)
Expression of the cloned bacteriophage phi X174 A* gene in Escherichia coli inhibits DNA replication and cell division (1985) (21)
Plasma Osteopontin Modulates Chronic Restraint Stress-Induced Thymus Atrophy by Regulating Stress Hormones: Inhibition by an Anti-Osteopontin Monoclonal Antibody1 (2009) (21)
A theory of DNA replication. (1972) (21)
Osteopontin regulates interleukin-17 production in hepatitis. (2012) (21)
Escherichia coli rep gene: identification of the promoter and N terminus of the rep protein (1985) (20)
Osteopontin-deficient bone cells are defective in their ability to produce NO in response to pulsatile fluid flow. (2001) (20)
Tissue Inhibitor of Metalloproteinases-1 Stimulates Gene Expression in MDA-MB-435 Human Breast Cancer Cells by Means of its Ability to Inhibit Metalloproteinases (2005) (19)
Comparative analysis of two alternative first exons reported for the mouse osteopontin gene. (1993) (18)
Spontaneous immortalization of mouse embryo cells: strain differences and changes in gene expression with particular reference to retroviral gag-pol genes. (1991) (18)
Multiple structures of adeno-associated virus DNA: analysis of terminally labeled molecules with endonuclease R-Hae III (1976) (18)
The rep mutation. VI. Purification and properties of the Escherichia coli rep protein, DNA helicase III. (1979) (18)
Induction of monocyte chemoattractant protein-1 by nicotine in pancreatic ductal adenocarcinoma cells: role of osteopontin. (2010) (18)
Osteopontin expression and function: Role in bone remodeling. (1998) (18)
Expression of Antisense Osteopontin RNA in Metastatic Mouse Fibroblasts Is Associated with Reduced Malignancy (1995) (18)
Differential screening of a cDNA library with cDNA probes amplified in a heterologous host: isolation of murine GRP78 (BiP) and other serum-regulated low-abundance mRNAs. (1989) (18)
Osteopontin Expression during Early Cerebral Ischemia-Reperfusion in Rats: Enhanced Expression in the Right Cortex Is Suppressed by Acetaminophen (2011) (17)
DNA gyrase and DNA unwinding (1979) (17)
Simian virus 40 T-antigen: identification of tryptic peptides in the C-terminal region and definition of the reading frame (1980) (17)
Osteoclasts resorb protein-free mineral (Osteologic discs) efficiently in the absence of osteopontin. (2005) (16)
A survey of vectors for regulating expression of cloned DNA in E. coli. (1988) (16)
Site of cleavage of superhelical phiX174 replicative form DNA by the single strand-specific Neurospora crassa endonuclease. (1976) (16)
The mitogen-regulated protein/proliferin transcript is degraded in primary mouse embryo fibroblast but not 3T3 nuclei: altered RNA processing correlates with immortalization. (1994) (16)
The mechanism of replication of phiX174 DNA. XIII. Discontinuous synthesis of the complementary strand in an Escherichia coli host with a temperature-sensitive polynucleotide ligase. (1975) (15)
Impaired angiogenic response in the corneas of mice lacking osteopontin. (2010) (15)
Vectors for the direct selection of cDNA clones corresponding to mammalian cell mRNA of low abundance. (1985) (15)
Regulation of Osteopontin Gene Expression in Osteoblasts a (1995) (15)
The mechanism of replication of φX174 DNA: XVI. Evidence that the φX174 viral strand is synthesized discontinuously☆☆☆ (1980) (15)
Effect of osteopontin on diarrhea duration and innate immunity in suckling mice infected with a murine rotavirus. (2009) (14)
The Escherichia coli rep Gene (1978) (14)
Thrombin-cleaved osteopontin regulates hemopoietic stem and progenitor cell functions through interactions with (cid:1) 9 (cid:2) 1 and (cid:1) 4 (cid:2) 1 integrins (2009) (14)
Mechanism of Replication of Single-Stranded φX174 DNA VII. Circularization of the Progeny Viral Strand (1973) (13)
The Third International Conference on Osteopontin and Related Proteins, San Antonio, Texas, May 10–12, 2002 (2004) (12)
THE RESISTANCE OF THE TOLERANT STATE TO X‐IRRADIATION (1960) (12)
Directed mutagenesis reveals that two histidines in tissue inhibitor of metalloproteinase-1 are each essential for the suppression of cell migration, invasion, and tumorigenicity. (1996) (12)
Presence of an N-terminal polyhistidine tag facilitates stable expression of an otherwise unstable N-terminal domain of mouse tissue inhibitor of metalloproteinase-1 in Escherichia coli. (1998) (12)
Mechanism of replication of bacteriophage phi X174. XXII. Site-specific mutagenesis of the A* gene reveals that A* protein is not essential for phi X174 DNA replication. (1987) (12)
The mechanism of replication of phiX174 single-stranded DNA. X. Distribution of the gaps in nascent phiX174 replicative form DNA. (1974) (12)
Anticarcinogenic Activities of Naturally Occurring Cysteine Proteinase Inhibitors (1993) (11)
Oncogenic consequences of down-modulating TIMP expression in 3T3 cells with antisense RNA. (1992) (11)
Osteopontin Expression Correlates with Melanoma Invasion**Please see these reviews for citations to many important earlier publications (2005) (11)
The rep mutation. VII. Cloning and analysis of the functional rep gene of Escherichia coli K-12. (1984) (11)
Isolation and characterization of self-complementary sequences from øX174 viral DNA (1975) (11)
Osteopontin Deficiency Suppresses Tumor Necrosis Factor-α–Induced Apoptosis in Chondrocytes (2012) (11)
Osteopontin deficiency enhances anabolic action of EP4 agonist at a sub-optimal dose in bone. (2007) (11)
The process of infection with bacteriophage phi-X174. 3. Phage maturation and lysis after synchronized infection. (1965) (10)
Structure of nascent phiX174 replicative form: evidence for discontinuous DNA replication. (1974) (10)
Ribonucleotides in DNA newly synthesised in 3T6 cells in vivo (1979) (10)
Mechanism of replication of bacteriophage phi X174 XIX. Initiation of phi X174 viral strand DNA synthesis at internal sites on the genome (1982) (10)
Crystallographically engineered, hydrothermally crystallized hydroxyapatite films: an in vitro study of bioactivity (2010) (8)
Both strands of polyoma DNA are replicated discontinuously with ribonucleotide primers in vivo (1981) (8)
Most short DNA molecules isolated from 3T3 cells are not nascent. (1978) (8)
The mechanism of replication of ΦX174. XVIII. Gene A and A∗ proteins of ΦX174 bind tightly to ΦX174 replicative form DNA (1981) (8)
Osteopontin is dispensable for protection against high load systemic fungal infection. (2008) (8)
The mechanism of replication of phi X174 single-stranded DNA. VI. Requirements for ribonucleoside triphosphates and DNA polymerase 3. (1973) (7)
DNA replication: A twofold amplifed view (1984) (7)
Mechanism of replication of phichi174 single-stranded DNA. V. Dispersive and conservative transfer of parental DNA into progeny DNA. (1973) (7)
The mechanism of replication of phiX174 DNA. XII. Non-random location of gaps in nascent phiX174 RF II DNA. (1975) (6)
DNA replication in vitro. I. Synthesis of single-stranded phi X174 DNA in crude lysates of phi X-infected E. coli. (1968) (6)
Eukaryotic DNA replication (1985) (6)
Structure‐Function Studies of Mouse Tissue Inhibitor of Metalloproteinases‐1 a (1994) (6)
Evidence that post-transcriptional changes in the expression of mitogen regulated protein accompany immortalization of mouse cells. (1987) (6)
The eukaryotic nucleus: A thematic issue (1988) (6)
Mechanism of replication of phichi174 single-stranded DNA. IV. The parental viral strand is not conserved in the replicating DNA structure. (1973) (6)
Instability of endogenous MRP/proliferin transcripts in the nucleus of mouse embryo fibroblasts contrasts with their stability when produced during transient transfections (1996) (5)
Characteristics of the nascent and non-nascent small DNA molecules found in Escherichia coli. (1983) (5)
Increased proteinase expression during tumor progression of tissue inhibitor of metalloproteinases cell lines down-modulated for levels: a new transformation paradigm? (1991) (5)
Mechanism of replication of bacteriophage phi X174 XX. Sensitivity of nascent DNA to single-strand-specific nucleases (1982) (4)
Osteopontin deficiency enhances parathyroid hormone/ parathyroid hormone related peptide receptor (PPR) signaling-induced alteration in tooth formation and odontoblastic morphology. (2011) (4)
Specialized plasmid vectors for cloning cDNA. (1988) (4)
A pBR322-derived vector for cloning blunt-ended cDNA: its use to detect molecular clones of low-abundance mRNAs. (1985) (4)
Production of nitric oxide by differentiated LSTRA cells is associated with expression of macrophage‐inducible nitric oxide synthase (1994) (4)
Effect of Antiserum to E. coli DNA Polymerase on Synthesis of ΦXI74 DNA in Extracts of ΦX-Infected Cells (1968) (4)
Adenovirus DNA replication in vivo: properties of short DNA molecules extracted from infected cells. (1982) (4)
Immunochemical comparison of transformation‐associated protein and secreted phosphoprotein (1990) (3)
An analysis of the clone size distribution of phi-X-174 mutants and recombinants. (1966) (3)
Overview: A Comparison of the Isometric and Filamentous Phages (1978) (3)
Specialized transduction of the rep gene of Escherichia coli (1977) (3)
Increased proteinase expression during tumor progression of cell lines down-modulated for TIMP levels: a new transformation paradigm? (2005) (3)
Biological information transfer (1977) (3)
A Possible Basis for Immunological Tolerance (1960) (3)
Hindlimb-unloading suppresses B cell population in the bone marrow and peripheral circulation associated with OPN expression in circulating blood cells (2014) (3)
Evidence for many nonnascent DNA molecules the size of Okazaki fragments in Escherichia coli and 3T3 cells: very few have 5'-terminal ribonucleotides. (1979) (3)
Contrasting effects of 2',3'-dideoxyadenosine on two steps in the replication of phi X 174 DNA in Escherichia coli. (1977) (2)
Is there induced DNA repair in mammalian cells? (1988) (2)
The mechanism of replication of phiX174. XVII. Purification and partial characterization of the gene A and A proteins. (1981) (2)
INTRACELLULAR OSTEOPONTIN IN OSTEOCLASTS: IMPAIRED MIGRATION, CELL FUSION AND RESORPTION IN OSTEOCLASTS FROM OPN-/- AND CD44-/- MICE (2002) (2)
Exposure of JB-6 mouse epidermal cells to 12-O-tetradecanoyl-phorbol-13-acetate is not accompanied by a significant change in total DNA-cytosine methylation. (1983) (1)
Nascent Pieces of ϕ X174 Viral-strand DNA Are Shorter Than Unit-length and Are Derived from All Regions of the Genome (1978) (1)
The mechanism of replication of phi x174 DNA. XVI. Evidence that the phi x174 viral strand is synthesized discontinuously. (1980) (1)
Regulation of Nuclear and Mitochondrial RNA Production after Serum Stimulation of Quiescent Mouse Cells (1984) (1)
Teaching by Research Fellows. (1965) (1)
Mechanism of Replication of Bacteriophage (X174 (2003) (1)
“Nick translation” in Escherichia coli rep strains deficient in DNA polymerase I activities (1979) (1)
Editorial: Third International Conference on Osteopontin and SIBLING (Small Integrin-Binding Ligand, N-linked Glycoprotein) Proteins (2002) (1)
Analysis of the conformational stability of the active domain of recombinant mouse TIMP-1 by intrinsic fluorescence. (1998) (1)
Evidence for preferential breakage of the minus strand of phi-X174 replicative form DNA by a T4-induced endonuclease. (1970) (1)
EVIDENCE FOR THE ABSENCE OF TRIPHOSPHATE TERMINI FROM THE 5' ENDS OF NEWLY SYNTHESIZED E.COLI DNA MOLECULES (1978) (1)
MOUSE ANTIMOUSE AND ANTIHUMAN OSTEOPONTIN ANTIBODIES: CREATION, CHARACTERIZATION, AND APPLICATION (2002) (1)
A FLUID FLOW RESPONSE DEFICIENCY OF OSTEOPONTIN KNOCK-OUT LONG BONE CELLS (2002) (1)
Comparison of restriction endonuclease HaeIII fragments of φX174, φXtB, and St-1: Evidence that φXtB is St-1 (1978) (1)
Mechanism ofReplication of/X174Single-Stranded DNA IX.Requirement fortheEscherichia coli dnaGProtein (1974) (1)
DISTINCT ROLES FOR OSTEOPONTIN IN KIDNEY STONE DISEASE (2002) (0)
Teaching by Research Fellows (1965) (0)
by activated RAW264 . 7 macrophages (1996) (0)
Estrogen is vasoprotective in osteopontin deficient mice (2003) (0)
Suppression of Corneal Neovascularization and TGF-Beta Signal in Osteopontin-Null Mice (2008) (0)
PTH ACTIVATION OF CORTICAL AND CANCELLOUS BONE FORMATION IN OSTEOPONTIN-DEFICIENT MICE (2002) (0)
Conference Summary (1992) (0)
A biophysical study of bacteriophage [phi]X-174 replication (1965) (0)
COLIPHAGE ϕX174 AND RELATED PHAGES (MICROVIRIDAE) (1999) (0)
Autoimmune Uveoretinitis in Mice Osteopontin Aggravates Experimental (2007) (0)
Commentary re: Q-T Le et al, identification of osteopontin as a prognostic marker for head and neck squamous cell carcinomas. clin cancer res, 9: 31-32, 2003. (2003) (0)
Isolation and characterization of self-complementary sequences from phiX174 viral DNA. (1975) (0)
Preface (1995) (0)
Acetaminophen and oxidant‐induced osteopontin in the myocardium (2008) (0)
Amnion Membranes by Murine Cancer Cells Suppression by Cathepsin L Inhibitors of the Invasion of Updated (2006) (0)
Impact of early life experience on adult health. (2017) (0)
THE ABORTIVE REPLICATION OF 4'X174 DNA IN A RECOMBINATION-DEFICIENT MUTANT OF ESCHERICHIA COLI * (0)
THE EXTRACELLULAR MATRIX PROTEIN OSTEOPONTIN IS AN ELEMENT OF THE HOST MUCOSAL DEFENSE AGAINST ROTAVIRUS DIARRHEA (2002) (0)
Folding and aggregation of designed proteins (1999) (0)
Comparison of restriction endonuclease HaeIII fragments of phiX174, phiXtB, and St-1: evidence that phiXtB is St-1. (1978) (0)
OSTEOPONTIN REGULATES CD44 EXPRESSION AND IS REQUIRED FOR NORMAL MACROPHAGE/OSTEOCLAST FUNCTION (2002) (0)
Immunological diseases of the eye (PP-099) (2010) (0)
Regulation of Gene Expression by the Tumor Promoter 12-O-Tetradecanoylphorbol -13-Acetate (2020) (0)
Transcription Factors and Cell Aging (1996) (0)
REGULATION OF OSTEOPONTIN: THE INSIDE STORY (2002) (0)
OSTEOPONTIN TRAFFIC IN STRESSED RENAL EPITHELIAL CELLS (2002) (0)
Books Received (1989) (0)
Effect of antiserum to E. coli DNA polymerase on synthesis of phi-X174 DNA in extracts of phi-X-infected cells. (1968) (0)
Mechanism of replication of phi-X-174 single stranded DNA. (1968) (0)
Osteopontin is required for mecha nical stress-dependent signals to bone marrow cells (2007) (0)
Preface/Front Matter (1978) (0)
The Present Status of ØX174 DNA Replication in Vivo (1978) (0)
Multiple Structures ofAdeno-Associated VirusDNA: Analysis ofTerminally Labeled Molecules withEndonuclease RHaeIII (1976) (0)
MOLECULAR MECHANISMS OF INTERACTION BETWEEN [alpha]V[beta]3 AND CD44 SIGNALING (2002) (0)
Metastasis: a current perspective (2008) (0)
Immunological diseases of the eye (WS-099) Chairpersons: Koh-hei Sonoda, Nobuyuki Ohguro (2010) (0)
Expression and secretion of active mouse TIMP-1 using a baculovirus expression vector (1994) (0)
Late abstracts 186–187 (2005) (0)
OSTEOPONTIN-DEFICIENCY REDUCES BONE FORMATION UNDER MECHANICAL STRESS (2002) (0)
REGULATION OF OSTEOPONTIN TRANSCRIPTION BY A RAS RESPONSE FACTOR (2002) (0)
JOINT DESTRUCTION IN ARTHRITIS IN MICE IS SUPPRESSED BY THE ABSENCE OF OSTEOPONTIN (2002) (0)
Antisense strategies come of age. Antisense strategies sponsored by the New York Academy of Sciences, Philadelphia, PA, USA, January 12-15, 1992. (1992) (0)
Osteopontin mediates neuroprotection via inhibition of inducible nitric oxide synthase (2005) (0)
Absence of Osteopontin Attenuates Infiltration of Inflammatory Cells in Female ApoE Null Mice (2003) (0)
Changes in Gene Expression During Senescence/Immortalization of Mouse Embryo Fibroblasts (2020) (0)
Identifying anti‐Osteopontin Monoclonal Antibodies that Inhibit the Formation of Colonies by Cancer Cells in Soft Agar (2011) (0)
Epigenetics and sports medicine (2016) (0)
The mechanism of replication of phi X 174. XVIII. Gene A and A* proteins of phi X 174 bind tightly to phi X 174 replicative form DNA. (1981) (0)
The resistance of the tolerant state to x-irradiation. (1960) (0)
Membrane Receptors and Signal Transduction Pathways in G1: Regulation of Liver Regeneration and T Cell Proliferation (2005) (0)
MODE OF OSTEOPONTIN ACTION AS A SURVIVAL FACTOR: STUDY OF OSTEOPONTIN-DEFICIENT 3T3 FIBROBLASTS (2002) (0)
STUDIES IN THE BLADDER OF MICE LACKING OSTEOPONTIN: SUGGESTED COMPENSATORY MECHANISMS (2002) (0)
C Function in Distinct and Interdependent Signaling Pathways in C3H 1OT/2 Fibroblasts (0)

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