David T. Denhardt
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(Suggest an Edit or Addition)David T. Denhardt's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- A membrane-filter technique for the detection of complementary DNA. (1966) (3458)
- Eta-1 (osteopontin): an early component of type-1 (cell-mediated) immunity. (2000) (1113)
- Osteopontin: a protein with diverse functions (1993) (1100)
- Osteopontin as a means to cope with environmental insults: regulation of inflammation, tissue remodeling, and cell survival. (2001) (1074)
- The Influence of the Proinflammatory Cytokine, Osteopontin, on Autoimmune Demyelinating Disease (2001) (805)
- Osteopontin, a key component of the hematopoietic stem cell niche and regulator of primitive hematopoietic progenitor cells. (2005) (779)
- Osteopontin is elevated during neointima formation in rat arteries and is a novel component of human atherosclerotic plaques. (1993) (687)
- Osteopontin: role in immune regulation and stress responses. (2011) (607)
- Signal-transducing protein phosphorylation cascades mediated by Ras/Rho proteins in the mammalian cell: the potential for multiplex signalling. (1996) (525)
- Antisense RNA-induced reduction in murine TIMP levels confers oncogenicity on Swiss 3T3 cells. (1989) (459)
- Identification of a DNA sequence responsible for binding of the 1,25-dihydroxyvitamin D3 receptor and 1,25-dihydroxyvitamin D3 enhancement of mouse secreted phosphoprotein 1 (SPP-1 or osteopontin) gene expression. (1990) (436)
- Mice Lacking Osteopontin Show Normal Development and Bone Structure but Display Altered Osteoclast Formation In Vitro (1998) (435)
- Osteopontin expression and function: Role in bone remodeling (1998) (413)
- Role of osteopontin in cellular signaling and toxicant injury. (2001) (345)
- Osteopontin-deficient mice are resistant to ovariectomy-induced bone resorption. (1999) (330)
- Tissue inhibitor of metalloproteinases (TIMP, aka EPA): structure, control of expression and biological functions. (1993) (285)
- Osteopontin deficiency produces osteoclast dysfunction due to reduced CD44 surface expression. (2003) (249)
- Control of osteopontin signaling and function by post‐translational phosphorylation and protein folding (2007) (248)
- Osteopontin expression in angiotensin II-induced tubulointerstitial nephritis. (1994) (245)
- Osteopontin, a transformation-associated cell adhesion phosphoprotein, is induced by 12-O-tetradecanoylphorbol 13-acetate in mouse epidermis. (1989) (245)
- Vectors: A Survey of Molecular Cloning Vectors and Their Uses (1987) (220)
- Osteopontin as a mediator of NKT cell function in T cell-mediated liver diseases. (2004) (208)
- Osteopontin deficiency protects joints against destruction in anti-type II collagen antibody-induced arthritis in mice (2002) (207)
- Unloading Induces Osteoblastic Cell Suppression and Osteoclastic Cell Activation to Lead to Bone Loss via Sympathetic Nervous System* (2005) (196)
- Osteopontin Deficiency Attenuates Atherosclerosis in Female Apolipoprotein E–Deficient Mice (2003) (194)
- Enhancement of Osteoclastic Bone Resorption and Suppression of Osteoblastic Bone Formation in Response to Reduced Mechanical Stress Do Not Occur in the Absence of Osteopontin (2001) (191)
- An Osteopontin‐Integrin Interaction Plays a Critical Role in Directing Adipogenesis and Osteogenesis by Mesenchymal Stem Cells (2014) (188)
- Osteopontin inhibits induction of nitric oxide synthase gene expression by inflammatory mediators in mouse kidney epithelial cells. (1994) (186)
- The rep mutation. IV. Slower movement of replication forks in Escherichia coli rep strains. (1975) (181)
- Thrombin-cleaved osteopontin regulates hemopoietic stem and progenitor cell functions through interactions with alpha9beta1 and alpha4beta1 integrins. (2009) (179)
- The single-stranded DNA phages. (1975) (179)
- Osteopontin Expression in Osteoblasts and Osteocytes During Bone Formation Under Mechanical Stress in the Calvarial Suture In Vivo (2003) (178)
- The murine gene encoding secreted phosphoprotein 1 (osteopontin): promoter structure, activity, and induction in vivo by estrogen and progesterone. (1991) (176)
- Role of Osteopontin in Cardiac Fibrosis and Remodeling in Angiotensin II–Induced Cardiac Hypertrophy (2004) (174)
- Osteopontin Function in Pathology: Lessons from Osteopontin-Deficient Mice (1999) (173)
- Osteopontin modulates CD44‐dependent chemotaxis of peritoneal macrophages through G‐protein‐coupled receptors: Evidence of a role for an intracellular form of osteopontin (2004) (173)
- Matrix metalloproteinases and tissue inhibitor of metalloproteinases: a review of their role in tumorigenesis and tissue invasion. (1989) (171)
- Gene expression during the mammalian cell cycle. (1986) (157)
- Reduced malignancy of ras-transformed NIH 3T3 cells expressing antisense osteopontin RNA. (1994) (157)
- Colocalization of Intracellular Osteopontin With CD44 Is Associated With Migration, Cell Fusion, and Resorption in Osteoclasts (2002) (156)
- Osteopontin facilitates angiogenesis, accumulation of osteoclasts, and resorption in ectopic bone. (2001) (155)
- Cysteine proteinase cathepsin L expression correlates closely with the metastatic potential of H-ras-transformed murine fibroblasts. (1987) (154)
- A growth-responsive gene (16C8) in normal mouse fibroblasts homologous to a human collagenase inhibitor with erythroid-potentiating activity: evidence for inducible and constitutive transcripts. (1986) (150)
- Osteopontin inhibits nitric oxide production and cytotoxicity by activated RAW264.7 macrophages (1996) (138)
- The ERR-1 orphan receptor is a transcriptional activator expressed during bone development. (1997) (137)
- Secreted phosphoprotein mrna is induced during multi‐stage carcinogenesis in mouse skin and correlates with the metastatic potential of murine fibroblasts (1990) (131)
- Cell Type-specific Post-translational Modifications of Mouse Osteopontin Are Associated with Different Adhesive Properties* (2007) (131)
- Molecular cloning of a tumor promoter‐inducible mRNA found in JB6 mouse epidermal cells: Induction is stable at high, but not at low, cell densities (1987) (129)
- The process of infection with bacteriophage φX174: III. Phage maturation and lysis after synchronized infection† (1965) (127)
- Expression genomics of cervical cancer: molecular classification and prediction of radiotherapy response by DNA microarray. (2003) (127)
- Increased thalamic neurodegeneration following ischaemic cortical stroke in osteopontin-deficient mice. (2006) (125)
- Identification of the major phosphoprotein secreted by many rodent cell lines as 2ar/osteopontin: enhanced expression in H-ras-transformed 3T3 cells. (1988) (117)
- Response to Comment on "The Influence of the Proinflammatory Cytokine, Osteopontin, on Autoimmune Demyelinating Disease" (2003) (117)
- Soluble osteopontin inhibits apoptosis of adherent endothelial cells deprived of growth factors * (2002) (117)
- An Osteopontin–NADPH Oxidase Signaling Cascade Promotes Pro–Matrix Metalloproteinase 9 Activation in Aortic Mesenchymal Cells (2006) (115)
- Osteopontin‐Induced Modifications of Cellular Functions a (1995) (114)
- Osteopontin expression correlates with melanoma invasion. (2005) (113)
- Transcriptional regulation of two serum-induced RNAs in mouse fibroblasts: equivalence of one species to B2 repetitive elements (1985) (112)
- Suppression by cathepsin L inhibitors of the invasion of amnion membranes by murine cancer cells. (1989) (109)
- Transcriptional regulation of osteopontin and the metastatic phenotype: Evidence for a Ras-activated enhancer in the human OPN promoter (2004) (107)
- Osteopontin Deficiency Reduces Experimental Tumor Cell Metastasis to Bone and Soft Tissues (2001) (107)
- Induction of expression of osteopontin (OPN; secreted phosphoprotein) in metastatic, ras-transformed NIH 3T3 cells. (1992) (106)
- Parathyroid Hormone-induced Bone Resorption Does Not Occur in the Absence of Osteopontin* (2001) (106)
- Resistance to Unloading‐Induced Three‐Dimensional Bone Loss in Osteopontin‐Deficient Mice (2002) (103)
- Increased expression of cathepsins L and B and decreased activity of their inhibitors in metastatic, ras‐transformed NIH 3T3 cells (1992) (102)
- Osteopontin is required for full expression of the transformed phenotype by the ras oncogene (2000) (100)
- Reduced tolerance to acute renal ischemia in mice with a targeted disruption of the osteopontin gene. (1999) (99)
- Identification of a ras-activated enhancer in the mouse osteopontin promoter and its interaction with a putative ETS-related transcription factor whose activity correlates with the metastatic potential of the cell (1995) (96)
- Osteopontin-Deficient Mice Exhibit Less Inflammation, Greater Tissue Damage, and Impaired Locomotor Recovery from Spinal Cord Injury Compared with Wild-Type Controls (2007) (95)
- Heterogeneity of osteopontin expression among nephrons in mouse kidneys and enhanced expression in sclerotic glomeruli. (1993) (91)
- Temporal expression of tissue inhibitors of metalloproteinases in mouse reproductive tissues during gestation (1993) (89)
- Sympathetic control of bone mass regulated by osteopontin (2011) (82)
- Rho-dependent Rho Kinase Activation Increases CD44 Surface Expression and Bone Resorption in Osteoclasts* (2003) (81)
- Osteopontin: an intrinsic inhibitor of inflammation in cartilage. (2001) (77)
- The process of infection with bacteriophage phi-X174. IV. Replication of the viral DNA in a synchronized infection. (1965) (76)
- THE ABORTIVE REPLICATION OF PhiX174 DNA IN A RECOMBINATION-DEFICIENT MUTANT OF Escherichia coli. (1967) (76)
- Age and development‐related changes in osteopontin and nitric oxide synthase mRNA levels in human kidney proximal tubule epithelial cells: Contrasting responses to hypoxia and reoxygenation (1994) (75)
- A study of mitochondrial and nuclear transcription with cloned cDNA probes. Changes in the relative abundance of mitochondrial transcripts after stimulation of quiescent mouse fibroblasts. (1985) (74)
- Osteopontin Facilitates Bone Resorption, Decreasing Bone Mineral Crystallinity and Content During Calcium Deficiency (2003) (74)
- The mechanism of replication of phi X174 single-stranded DNA. 3. An enzymic study of the structure of the replicative form II DNA. (1971) (71)
- Tissue inhibitor of metalloproteinase-1 stimulates proliferation of human cancer cells by inhibiting a metalloproteinase (2004) (70)
- Accelerated development of aging-associated and instability-induced osteoarthritis in osteopontin-deficient mice. (2009) (70)
- Osteopontin regulates hindlimb-unloading-induced lymphoid organ atrophy and weight loss by modulating corticosteroid production (2007) (70)
- The rep Mutation III. Altered Structure of the Replicating Escherichia coli Chromosome (1974) (68)
- Regulation of the mRNA for monocyte-derived neutrophil-activating peptide in differentiating HL60 promyelocytes (1989) (67)
- Osteopontin deficiency protects against aldosterone-induced inflammation, oxidative stress, and interstitial fibrosis in the kidney. (2011) (67)
- Increased expression of the remodeling- and tumorigenic-associated factor osteopontin in pyramidal neurons of the Alzheimer's disease brain. (2007) (66)
- Studies on phiX174 proteins. I. Phage-specific proteins synthesized after infection of Escherichia coli. (1969) (66)
- Osteopontin deficiency and aging on nanomechanics of mouse bone. (2007) (64)
- Identification of a serum-inducible messenger RNA (5B10) as the mouse homologue of calcyclin: tissue distribution and expression in metastatic, ras-transformed NIH 3T3 cells. (1990) (62)
- Sensitivity of superhelical DNA to a single-strand specific endonuclease. (1973) (58)
- Antagonistic effects of transforming growth factor-beta on vitamin D3 enhancement of osteocalcin and osteopontin transcription: reduced interactions of vitamin D receptor/retinoid X receptor complexes with vitamin E response elements. (1996) (58)
- Close relationship of the major excreted protein of transformed murine fibroblasts to thiol-dependent cathepsins. (1986) (57)
- Osteopontin is required for mechanical stress-dependent signals to bone marrow cells. (2007) (57)
- Oncogene-initiated aberrant signaling engenders the metastatic phenotype: synergistic transcription factor interactions are targets for cancer therapy. (1996) (54)
- Corneal wound healing in an osteopontin-deficient mouse. (2008) (53)
- Mechanism of Action of Antisense RNA. Sometime Inhibition of Transcription, Processing, Transport, or Translation a (1992) (52)
- Differential effects of osteopontin on the cytotoxic activity of macrophages from young and old mice (1996) (51)
- Osteopontin (OPN) may facilitate metastasis by protecting cells from macrophage NO-mediated cytotoxicity: evidence from cell lines down-regulated for OPN expression by a targeted ribozyme (1995) (50)
- Serum osteopontin, an enhancer of tumor metastasis to bone, promotes B16 melanoma cell migration (2007) (50)
- Expression of attachment proteins during cementogenesis. (1990) (50)
- Regulation of Collagenase-3 and Osteocalcin Gene Expression by Collagen and Osteopontin in Differentiating MC3T3-E1 Cells* (2002) (50)
- Deficiency of MMP17/MT4-MMP proteolytic activity predisposes to aortic aneurysm in mice. (2015) (49)
- Characterization of a cDNA clone encoding murine mitogen-regulated protein: regulation of mRNA levels in mortal and immortal cell lines (1985) (49)
- Prenatal Detection of Embryo Resorption in Osteopontin-Deficient Mice Using Serial Noninvasive Magnetic Resonance Microscopy (2004) (48)
- Stimulation of Mouse Osteopontin Promoter by v-Src Is Mediated by a CCAAT Box-binding Factor* (1996) (48)
- Comparison of the effect of ultraviolet radiation and ethidium bromide intercalation on the conformation of superhelical phiX174 replicative form DNA. (1973) (48)
- The rep mutation. II. Its effect on Escherichia coli and on the replication of bacteriophage phi X174. (1972) (47)
- Osteopontin deficiency induces parathyroid hormone enhancement of cortical bone formation. (2003) (47)
- p53 mutations in spontaneously immortalized 3T12 but not 3T3 mouse embryo cells. (1992) (47)
- Effect of cyanide and carbon monoxide on the replication of bacterial DNA in vivo. (1968) (46)
- The Cytokine Osteopontin Modulates the Severity of Rotavirus Diarrhea (2005) (46)
- Mechanisms of cellular invasiveness: a comparison of amnion invasion in vitro and metastatic behavior in vivo. (1989) (45)
- Osteopontin is associated with nuclear factor kappaB gene expression during tail-suspension-induced bone loss. (2006) (45)
- OPN deficiency suppresses appearance of odontoclastic cells and resorption of the tooth root induced by experimental force application (2008) (44)
- Escherichia coli rep gene: sequence of the gene, the encoded helicase, and its homology with uvrD. (1987) (42)
- Involvement of Osteopontin in the Matrix-Degrading and Proangiogenic Changes Mediated by Nicotine in Pancreatic Cancer Cells (2010) (41)
- Osteopontin Negatively Regulates Parathyroid Hormone Receptor Signaling in Osteoblasts* (2008) (40)
- Induction of osteopontin expression by nicotine and cigarette smoke in the pancreas and pancreatic ductal adenocarcinoma cells (2009) (39)
- Osteopontin regulates development and function of invariant natural killer T cells (2008) (38)
- Expression of a prometastatic splice variant of osteopontin, OPNC, in human pancreatic ductal adenocarcinoma. (2009) (38)
- The process of infection with bacteriophage phi-XD174. VI. Inactivation of infected complexes by ultraviolet irradiation. (1965) (37)
- Developmental expression of cathepsin L and c‐rasHa in the mouse placenta (1991) (37)
- An analysis of the clone size distribution of ΦX174 mutants and recombinants (1966) (36)
- The role of osteopontin in tendon tissue remodeling after denervation-induced mechanical stress deprivation. (2007) (35)
- The mechanism of replication of phi X174 single-stranded DNA. II. The role of viral proteins. (1971) (35)
- Effect of stress on human biology: Epigenetics, adaptation, inheritance, and social significance (2018) (34)
- Inhibition of synthesis of phiX174 DNA in a mutant host thermosensitive for DNA synthesis. (1968) (33)
- Osteopontin expression detected in adult cochleæ and inner ear fluids (1995) (33)
- Adhesion Molecules in Renal Disease (1999) (33)
- The Process of Infection with Bacteriophage φX174: V. Inactivation of the Phage-Bacterium Complex by Decay of ^(32)P incorporated in the Infecting Particle (1965) (32)
- The Escherichia coli rep mutation. X. Consequences of increased and decreased Rep protein levels (1987) (32)
- Osteopontin deficiency impairs wear debris-induced osteolysis via regulation of cytokine secretion from murine macrophages. (2010) (31)
- Characterization of a mouse mitogen-regulated protein/proliferin gene and its promoter: a member of the growth hormone/prolactin gene superfamily. (1989) (31)
- Formation of ribosylthymine in Escherichia coli. Studies on pulse labeling with thymine and thymidine. (1969) (31)
- Osteopontin affects the persistence of beta-glucan-induced hepatic granuloma formation and tissue injury through two distinct mechanisms. (2004) (31)
- A human promyelocyte mRNA transiently induced by TPA is homologous to yeast IPP isomerase. (1994) (31)
- Loss of osteopontin perturbs the epithelial-mesenchymal transition in an injured mouse lens epithelium (2007) (31)
- Cell cycle-regulated and proliferation stimulus-responsive genes. (1991) (31)
- Helix-loop-helix-type transcription factor (HES-1) is expressed in osteoblastic cells, suppressed by 1,25(OH)2 vitamin D3, and modulates 1,25(OH)2 vitamin D3 enhancement of osteopontin gene expression. (1997) (30)
- Role of Osteopontin in Murine Lyme Arthritis and Host Defense against Borrelia burgdorferi (2002) (29)
- Mechanism of Replication of φX174 Single-Stranded DNA IX. Requirement for the Escherichia coli dnaG Protein (1974) (29)
- The Isometric Single-Stranded DNA Phages (1977) (28)
- Acetaminophen Attenuates Doxorubicin-Induced Cardiac Fibrosis Via Osteopontin and GATA4 Regulation: Reduction of Oxidant Levels (2013) (28)
- Modulation of translation by the 5' leader sequence of the mRNA encoding murine tissue inhibitor of metalloproteinases. (1990) (27)
- Physical map and strand polarity of specific fragments of adenovirus-associated virus DNA produced by endonuclease R-EcoRI (1975) (27)
- Osteopontin deficiency suppresses high phosphate load-induced bone loss via specific modulation of osteoclasts. (2006) (27)
- Osteopontin Traffic in Hypoxic Renal Epithelial Cells (2003) (27)
- Characterization of the complex between SV40 large T antigen and the 53K host protein in transformed mouse cells. (1980) (26)
- Osteopontin Participates in Th1-Mediated Host Resistance against Nonlethal Malaria Parasite Plasmodium chabaudi chabaudi Infection in Mice (2006) (26)
- On the use of anti-sense RNA: down-regulation of mRNA encoding a metalloproteinase inhibitor. (1987) (25)
- Lack of in vivo function of osteopontin in experimental anti-GBM nephritis. (2000) (25)
- Cloning and characterization of murine carnitine acetyltransferase: evidence for a requirement during cell cycle progression. (1997) (25)
- The mechanism of replication of øX174 DNA (1975) (24)
- Evidence for two pathways of protein kinase C induction of 2AR expression: Correlation with mitogenesis (1989) (23)
- Establishment and characterization of bone marrow stromal cell lines that support osteoclastogenesis. (1995) (23)
- Aprt/Opn double knockout mice: osteopontin is a modifier of kidney stone disease severity. (2005) (23)
- Evidence for the presence of ribonucleotides at the 5' termini of some DNA molecules isolated from Escherichia coli polAex2. (1977) (23)
- Regulation of no synthesis induced by inflammatory mediators in RAW264.7 cells: collagen prevents inhibition by osteopontin. (2000) (22)
- Ultraviolet light irradiation of PM2 superhelical DNA. (1977) (22)
- Characterization of osteopontin expression and function after status epilepticus (2008) (22)
- Regulation of the expression of mitogen-regulated protein (MRP; proliferin) and cathepsin L in cultured cells and in the murine placenta (1991) (21)
- Osteopontin: Role in Cell Signalling and Adhesion (1995) (21)
- p21ras and protein kinase C function in distinct and interdependent signaling pathways in C3H 10T1/2 fibroblasts (1993) (21)
- Osteopontin expression and function within the dorsal root ganglion (2007) (21)
- Expression of the cloned bacteriophage phi X174 A* gene in Escherichia coli inhibits DNA replication and cell division (1985) (21)
- Plasma Osteopontin Modulates Chronic Restraint Stress-Induced Thymus Atrophy by Regulating Stress Hormones: Inhibition by an Anti-Osteopontin Monoclonal Antibody1 (2009) (21)
- A theory of DNA replication. (1972) (21)
- Osteopontin regulates interleukin-17 production in hepatitis. (2012) (21)
- Escherichia coli rep gene: identification of the promoter and N terminus of the rep protein (1985) (20)
- Osteopontin-deficient bone cells are defective in their ability to produce NO in response to pulsatile fluid flow. (2001) (20)
- Tissue Inhibitor of Metalloproteinases-1 Stimulates Gene Expression in MDA-MB-435 Human Breast Cancer Cells by Means of its Ability to Inhibit Metalloproteinases (2005) (19)
- Comparative analysis of two alternative first exons reported for the mouse osteopontin gene. (1993) (18)
- Spontaneous immortalization of mouse embryo cells: strain differences and changes in gene expression with particular reference to retroviral gag-pol genes. (1991) (18)
- Multiple structures of adeno-associated virus DNA: analysis of terminally labeled molecules with endonuclease R-Hae III (1976) (18)
- The rep mutation. VI. Purification and properties of the Escherichia coli rep protein, DNA helicase III. (1979) (18)
- Induction of monocyte chemoattractant protein-1 by nicotine in pancreatic ductal adenocarcinoma cells: role of osteopontin. (2010) (18)
- Osteopontin expression and function: Role in bone remodeling. (1998) (18)
- Expression of Antisense Osteopontin RNA in Metastatic Mouse Fibroblasts Is Associated with Reduced Malignancy (1995) (18)
- Differential screening of a cDNA library with cDNA probes amplified in a heterologous host: isolation of murine GRP78 (BiP) and other serum-regulated low-abundance mRNAs. (1989) (18)
- Osteopontin Expression during Early Cerebral Ischemia-Reperfusion in Rats: Enhanced Expression in the Right Cortex Is Suppressed by Acetaminophen (2011) (17)
- DNA gyrase and DNA unwinding (1979) (17)
- Simian virus 40 T-antigen: identification of tryptic peptides in the C-terminal region and definition of the reading frame (1980) (17)
- Osteoclasts resorb protein-free mineral (Osteologic discs) efficiently in the absence of osteopontin. (2005) (16)
- A survey of vectors for regulating expression of cloned DNA in E. coli. (1988) (16)
- Site of cleavage of superhelical phiX174 replicative form DNA by the single strand-specific Neurospora crassa endonuclease. (1976) (16)
- The mitogen-regulated protein/proliferin transcript is degraded in primary mouse embryo fibroblast but not 3T3 nuclei: altered RNA processing correlates with immortalization. (1994) (16)
- The mechanism of replication of phiX174 DNA. XIII. Discontinuous synthesis of the complementary strand in an Escherichia coli host with a temperature-sensitive polynucleotide ligase. (1975) (15)
- Impaired angiogenic response in the corneas of mice lacking osteopontin. (2010) (15)
- Vectors for the direct selection of cDNA clones corresponding to mammalian cell mRNA of low abundance. (1985) (15)
- Regulation of Osteopontin Gene Expression in Osteoblasts a (1995) (15)
- The mechanism of replication of φX174 DNA: XVI. Evidence that the φX174 viral strand is synthesized discontinuously☆☆☆ (1980) (15)
- Effect of osteopontin on diarrhea duration and innate immunity in suckling mice infected with a murine rotavirus. (2009) (14)
- The Escherichia coli rep Gene (1978) (14)
- Thrombin-cleaved osteopontin regulates hemopoietic stem and progenitor cell functions through interactions with (cid:1) 9 (cid:2) 1 and (cid:1) 4 (cid:2) 1 integrins (2009) (14)
- Mechanism of Replication of Single-Stranded φX174 DNA VII. Circularization of the Progeny Viral Strand (1973) (13)
- The Third International Conference on Osteopontin and Related Proteins, San Antonio, Texas, May 10–12, 2002 (2004) (12)
- THE RESISTANCE OF THE TOLERANT STATE TO X‐IRRADIATION (1960) (12)
- Directed mutagenesis reveals that two histidines in tissue inhibitor of metalloproteinase-1 are each essential for the suppression of cell migration, invasion, and tumorigenicity. (1996) (12)
- Presence of an N-terminal polyhistidine tag facilitates stable expression of an otherwise unstable N-terminal domain of mouse tissue inhibitor of metalloproteinase-1 in Escherichia coli. (1998) (12)
- Mechanism of replication of bacteriophage phi X174. XXII. Site-specific mutagenesis of the A* gene reveals that A* protein is not essential for phi X174 DNA replication. (1987) (12)
- The mechanism of replication of phiX174 single-stranded DNA. X. Distribution of the gaps in nascent phiX174 replicative form DNA. (1974) (12)
- Anticarcinogenic Activities of Naturally Occurring Cysteine Proteinase Inhibitors (1993) (11)
- Oncogenic consequences of down-modulating TIMP expression in 3T3 cells with antisense RNA. (1992) (11)
- Osteopontin Expression Correlates with Melanoma Invasion**Please see these reviews for citations to many important earlier publications (2005) (11)
- The rep mutation. VII. Cloning and analysis of the functional rep gene of Escherichia coli K-12. (1984) (11)
- Isolation and characterization of self-complementary sequences from øX174 viral DNA (1975) (11)
- Osteopontin Deficiency Suppresses Tumor Necrosis Factor-α–Induced Apoptosis in Chondrocytes (2012) (11)
- Osteopontin deficiency enhances anabolic action of EP4 agonist at a sub-optimal dose in bone. (2007) (11)
- The process of infection with bacteriophage phi-X174. 3. Phage maturation and lysis after synchronized infection. (1965) (10)
- Structure of nascent phiX174 replicative form: evidence for discontinuous DNA replication. (1974) (10)
- Ribonucleotides in DNA newly synthesised in 3T6 cells in vivo (1979) (10)
- Mechanism of replication of bacteriophage phi X174 XIX. Initiation of phi X174 viral strand DNA synthesis at internal sites on the genome (1982) (10)
- Crystallographically engineered, hydrothermally crystallized hydroxyapatite films: an in vitro study of bioactivity (2010) (8)
- Both strands of polyoma DNA are replicated discontinuously with ribonucleotide primers in vivo (1981) (8)
- Most short DNA molecules isolated from 3T3 cells are not nascent. (1978) (8)
- The mechanism of replication of ΦX174. XVIII. Gene A and A∗ proteins of ΦX174 bind tightly to ΦX174 replicative form DNA (1981) (8)
- Osteopontin is dispensable for protection against high load systemic fungal infection. (2008) (8)
- The mechanism of replication of phi X174 single-stranded DNA. VI. Requirements for ribonucleoside triphosphates and DNA polymerase 3. (1973) (7)
- DNA replication: A twofold amplifed view (1984) (7)
- Mechanism of replication of phichi174 single-stranded DNA. V. Dispersive and conservative transfer of parental DNA into progeny DNA. (1973) (7)
- The mechanism of replication of phiX174 DNA. XII. Non-random location of gaps in nascent phiX174 RF II DNA. (1975) (6)
- DNA replication in vitro. I. Synthesis of single-stranded phi X174 DNA in crude lysates of phi X-infected E. coli. (1968) (6)
- Eukaryotic DNA replication (1985) (6)
- Structure‐Function Studies of Mouse Tissue Inhibitor of Metalloproteinases‐1 a (1994) (6)
- Evidence that post-transcriptional changes in the expression of mitogen regulated protein accompany immortalization of mouse cells. (1987) (6)
- The eukaryotic nucleus: A thematic issue (1988) (6)
- Mechanism of replication of phichi174 single-stranded DNA. IV. The parental viral strand is not conserved in the replicating DNA structure. (1973) (6)
- Instability of endogenous MRP/proliferin transcripts in the nucleus of mouse embryo fibroblasts contrasts with their stability when produced during transient transfections (1996) (5)
- Characteristics of the nascent and non-nascent small DNA molecules found in Escherichia coli. (1983) (5)
- Increased proteinase expression during tumor progression of tissue inhibitor of metalloproteinases cell lines down-modulated for levels: a new transformation paradigm? (1991) (5)
- Mechanism of replication of bacteriophage phi X174 XX. Sensitivity of nascent DNA to single-strand-specific nucleases (1982) (4)
- Osteopontin deficiency enhances parathyroid hormone/ parathyroid hormone related peptide receptor (PPR) signaling-induced alteration in tooth formation and odontoblastic morphology. (2011) (4)
- Specialized plasmid vectors for cloning cDNA. (1988) (4)
- A pBR322-derived vector for cloning blunt-ended cDNA: its use to detect molecular clones of low-abundance mRNAs. (1985) (4)
- Production of nitric oxide by differentiated LSTRA cells is associated with expression of macrophage‐inducible nitric oxide synthase (1994) (4)
- Effect of Antiserum to E. coli DNA Polymerase on Synthesis of ΦXI74 DNA in Extracts of ΦX-Infected Cells (1968) (4)
- Adenovirus DNA replication in vivo: properties of short DNA molecules extracted from infected cells. (1982) (4)
- Immunochemical comparison of transformation‐associated protein and secreted phosphoprotein (1990) (3)
- An analysis of the clone size distribution of phi-X-174 mutants and recombinants. (1966) (3)
- Overview: A Comparison of the Isometric and Filamentous Phages (1978) (3)
- Specialized transduction of the rep gene of Escherichia coli (1977) (3)
- Increased proteinase expression during tumor progression of cell lines down-modulated for TIMP levels: a new transformation paradigm? (2005) (3)
- Biological information transfer (1977) (3)
- A Possible Basis for Immunological Tolerance (1960) (3)
- Hindlimb-unloading suppresses B cell population in the bone marrow and peripheral circulation associated with OPN expression in circulating blood cells (2014) (3)
- Evidence for many nonnascent DNA molecules the size of Okazaki fragments in Escherichia coli and 3T3 cells: very few have 5'-terminal ribonucleotides. (1979) (3)
- Contrasting effects of 2',3'-dideoxyadenosine on two steps in the replication of phi X 174 DNA in Escherichia coli. (1977) (2)
- Is there induced DNA repair in mammalian cells? (1988) (2)
- The mechanism of replication of phiX174. XVII. Purification and partial characterization of the gene A and A proteins. (1981) (2)
- INTRACELLULAR OSTEOPONTIN IN OSTEOCLASTS: IMPAIRED MIGRATION, CELL FUSION AND RESORPTION IN OSTEOCLASTS FROM OPN-/- AND CD44-/- MICE (2002) (2)
- Exposure of JB-6 mouse epidermal cells to 12-O-tetradecanoyl-phorbol-13-acetate is not accompanied by a significant change in total DNA-cytosine methylation. (1983) (1)
- Nascent Pieces of ϕ X174 Viral-strand DNA Are Shorter Than Unit-length and Are Derived from All Regions of the Genome (1978) (1)
- The mechanism of replication of phi x174 DNA. XVI. Evidence that the phi x174 viral strand is synthesized discontinuously. (1980) (1)
- Regulation of Nuclear and Mitochondrial RNA Production after Serum Stimulation of Quiescent Mouse Cells (1984) (1)
- Teaching by Research Fellows. (1965) (1)
- Mechanism of Replication of Bacteriophage (X174 (2003) (1)
- “Nick translation” in Escherichia coli rep strains deficient in DNA polymerase I activities (1979) (1)
- Editorial: Third International Conference on Osteopontin and SIBLING (Small Integrin-Binding Ligand, N-linked Glycoprotein) Proteins (2002) (1)
- Analysis of the conformational stability of the active domain of recombinant mouse TIMP-1 by intrinsic fluorescence. (1998) (1)
- Evidence for preferential breakage of the minus strand of phi-X174 replicative form DNA by a T4-induced endonuclease. (1970) (1)
- EVIDENCE FOR THE ABSENCE OF TRIPHOSPHATE TERMINI FROM THE 5' ENDS OF NEWLY SYNTHESIZED E.COLI DNA MOLECULES (1978) (1)
- MOUSE ANTIMOUSE AND ANTIHUMAN OSTEOPONTIN ANTIBODIES: CREATION, CHARACTERIZATION, AND APPLICATION (2002) (1)
- A FLUID FLOW RESPONSE DEFICIENCY OF OSTEOPONTIN KNOCK-OUT LONG BONE CELLS (2002) (1)
- Comparison of restriction endonuclease HaeIII fragments of φX174, φXtB, and St-1: Evidence that φXtB is St-1 (1978) (1)
- Mechanism ofReplication of/X174Single-Stranded DNA IX.Requirement fortheEscherichia coli dnaGProtein (1974) (1)
- DISTINCT ROLES FOR OSTEOPONTIN IN KIDNEY STONE DISEASE (2002) (0)
- Teaching by Research Fellows (1965) (0)
- by activated RAW264 . 7 macrophages (1996) (0)
- Estrogen is vasoprotective in osteopontin deficient mice (2003) (0)
- Suppression of Corneal Neovascularization and TGF-Beta Signal in Osteopontin-Null Mice (2008) (0)
- PTH ACTIVATION OF CORTICAL AND CANCELLOUS BONE FORMATION IN OSTEOPONTIN-DEFICIENT MICE (2002) (0)
- Conference Summary (1992) (0)
- A biophysical study of bacteriophage [phi]X-174 replication (1965) (0)
- COLIPHAGE ϕX174 AND RELATED PHAGES (MICROVIRIDAE) (1999) (0)
- Autoimmune Uveoretinitis in Mice Osteopontin Aggravates Experimental (2007) (0)
- Commentary re: Q-T Le et al, identification of osteopontin as a prognostic marker for head and neck squamous cell carcinomas. clin cancer res, 9: 31-32, 2003. (2003) (0)
- Isolation and characterization of self-complementary sequences from phiX174 viral DNA. (1975) (0)
- Preface (1995) (0)
- Acetaminophen and oxidant‐induced osteopontin in the myocardium (2008) (0)
- Amnion Membranes by Murine Cancer Cells Suppression by Cathepsin L Inhibitors of the Invasion of Updated (2006) (0)
- Impact of early life experience on adult health. (2017) (0)
- THE ABORTIVE REPLICATION OF 4'X174 DNA IN A RECOMBINATION-DEFICIENT MUTANT OF ESCHERICHIA COLI * (0)
- THE EXTRACELLULAR MATRIX PROTEIN OSTEOPONTIN IS AN ELEMENT OF THE HOST MUCOSAL DEFENSE AGAINST ROTAVIRUS DIARRHEA (2002) (0)
- Folding and aggregation of designed proteins (1999) (0)
- Comparison of restriction endonuclease HaeIII fragments of phiX174, phiXtB, and St-1: evidence that phiXtB is St-1. (1978) (0)
- OSTEOPONTIN REGULATES CD44 EXPRESSION AND IS REQUIRED FOR NORMAL MACROPHAGE/OSTEOCLAST FUNCTION (2002) (0)
- Immunological diseases of the eye (PP-099) (2010) (0)
- Regulation of Gene Expression by the Tumor Promoter 12-O-Tetradecanoylphorbol -13-Acetate (2020) (0)
- Transcription Factors and Cell Aging (1996) (0)
- REGULATION OF OSTEOPONTIN: THE INSIDE STORY (2002) (0)
- OSTEOPONTIN TRAFFIC IN STRESSED RENAL EPITHELIAL CELLS (2002) (0)
- Books Received (1989) (0)
- Effect of antiserum to E. coli DNA polymerase on synthesis of phi-X174 DNA in extracts of phi-X-infected cells. (1968) (0)
- Mechanism of replication of phi-X-174 single stranded DNA. (1968) (0)
- Osteopontin is required for mecha nical stress-dependent signals to bone marrow cells (2007) (0)
- Preface/Front Matter (1978) (0)
- The Present Status of ØX174 DNA Replication in Vivo (1978) (0)
- Multiple Structures ofAdeno-Associated VirusDNA: Analysis ofTerminally Labeled Molecules withEndonuclease RHaeIII (1976) (0)
- MOLECULAR MECHANISMS OF INTERACTION BETWEEN [alpha]V[beta]3 AND CD44 SIGNALING (2002) (0)
- Metastasis: a current perspective (2008) (0)
- Immunological diseases of the eye (WS-099) Chairpersons: Koh-hei Sonoda, Nobuyuki Ohguro (2010) (0)
- Expression and secretion of active mouse TIMP-1 using a baculovirus expression vector (1994) (0)
- Late abstracts 186–187 (2005) (0)
- OSTEOPONTIN-DEFICIENCY REDUCES BONE FORMATION UNDER MECHANICAL STRESS (2002) (0)
- REGULATION OF OSTEOPONTIN TRANSCRIPTION BY A RAS RESPONSE FACTOR (2002) (0)
- JOINT DESTRUCTION IN ARTHRITIS IN MICE IS SUPPRESSED BY THE ABSENCE OF OSTEOPONTIN (2002) (0)
- Antisense strategies come of age. Antisense strategies sponsored by the New York Academy of Sciences, Philadelphia, PA, USA, January 12-15, 1992. (1992) (0)
- Osteopontin mediates neuroprotection via inhibition of inducible nitric oxide synthase (2005) (0)
- Absence of Osteopontin Attenuates Infiltration of Inflammatory Cells in Female ApoE Null Mice (2003) (0)
- Changes in Gene Expression During Senescence/Immortalization of Mouse Embryo Fibroblasts (2020) (0)
- Identifying anti‐Osteopontin Monoclonal Antibodies that Inhibit the Formation of Colonies by Cancer Cells in Soft Agar (2011) (0)
- Epigenetics and sports medicine (2016) (0)
- The mechanism of replication of phi X 174. XVIII. Gene A and A* proteins of phi X 174 bind tightly to phi X 174 replicative form DNA. (1981) (0)
- The resistance of the tolerant state to x-irradiation. (1960) (0)
- Membrane Receptors and Signal Transduction Pathways in G1: Regulation of Liver Regeneration and T Cell Proliferation (2005) (0)
- MODE OF OSTEOPONTIN ACTION AS A SURVIVAL FACTOR: STUDY OF OSTEOPONTIN-DEFICIENT 3T3 FIBROBLASTS (2002) (0)
- STUDIES IN THE BLADDER OF MICE LACKING OSTEOPONTIN: SUGGESTED COMPENSATORY MECHANISMS (2002) (0)
- C Function in Distinct and Interdependent Signaling Pathways in C3H 1OT/2 Fibroblasts (0)
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