Duanqing Pei
#109,903
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Chinese doctor and scientist
Duanqing Pei's AcademicInfluence.com Rankings
Duanqing Peiphilosophy Degrees
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#11209
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Logic
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#6303
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Duanqing Peibiology Degrees
Biology
#10679
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#14030
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Molecular Biology
#1575
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#1603
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Philosophy Biology
Duanqing Pei's Degrees
- Bachelors Medicine Tsinghua University
Why Is Duanqing Pei Influential?
(Suggest an Edit or Addition)According to Wikipedia, Dr. Duanqing Pei is a research scientist who specializes in regenerative medicine. Originally from a small agricultural college in southern China, Dr. Pei went on to complete his graduate work at and obtained his PhD from the University of Pennsylvania in 1991. He then became a postdoctoral fellow at the University of Michigan before becoming a faculty member at the University of Minnesota School of Medicine in 1996. He joined the medical faculty at Tsinghua University in Beijing, China in 2002 and became the head of the pharmacology department soon after. In 2004, Dr. Pei moved to the newly formed Guangzhou Institute of Biomedicine and Health and took on the position of Deputy Director General. In the spring of 2009, he was promoted to Director General.
Duanqing Pei's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts. (2010) (1075)
- Vitamin C enhances the generation of mouse and human induced pluripotent stem cells. (2010) (893)
- Furin-dependent intracellular activation of the human stromelysin-3 zymogen (1995) (678)
- Genomic instability in laminopathy-based premature aging (2005) (624)
- Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases (2005) (556)
- Generation of human induced pluripotent stem cells from urine samples (2012) (474)
- H3K9 methylation is a barrier during somatic cell reprogramming into iPSCs (2012) (446)
- The histone demethylases Jhdm1a/1b enhance somatic cell reprogramming in a vitamin-C-dependent manner. (2011) (404)
- Generation of Induced Pluripotent Stem Cell Lines from Tibetan Miniature Pig* (2009) (389)
- Stem cell pluripotency and transcription factor Oct4 (2002) (345)
- Generation of induced pluripotent stem cells from urine. (2011) (339)
- Hallmarks of pluripotency (2015) (322)
- Tet and TDG mediate DNA demethylation essential for mesenchymal-to-epithelial transition in somatic cell reprogramming. (2014) (284)
- Regulation of membrane-type matrix metalloproteinase 1 activity by dynamin-mediated endocytosis (2001) (262)
- Vitamin C modulates TET1 function during somatic cell reprogramming (2013) (258)
- Identification and Characterization of the Fifth Membrane-type Matrix Metalloproteinase MT5-MMP* (1999) (257)
- MicroRNA Cluster 302–367 Enhances Somatic Cell Reprogramming by Accelerating a Mesenchymal-to-Epithelial Transition* (2011) (257)
- A negative feedback loop of transcription factors that controls stem cell pluripotency and self‐renewal (2006) (252)
- A negative feedback loop of transcription factors that controls stem cell pluripotency and self‐renewal (2006) (252)
- Treating COVID-19 with Chloroquine (2020) (236)
- Hydrolytic inactivation of a breast carcinoma cell-derived serpin by human stromelysin-3. (1994) (229)
- Membrane type-matrix metalloproteinases (MT-MMP). (2003) (219)
- Leukolysin/MMP25/MT6-MMP: a novel matrix metalloproteinase specifically expressed in the leukocyte lineage (1999) (210)
- Regulation of the Pluripotency Marker Rex-1 by Nanog and Sox2* (2006) (202)
- Sequential introduction of reprogramming factors reveals a time-sensitive requirement for individual factors and a sequential EMT–MET mechanism for optimal reprogramming (2013) (192)
- Establishment of porcine and human expanded potential stem cells (2019) (190)
- Identification of Niclosamide as a New Small-Molecule Inhibitor of the STAT3 Signaling Pathway. (2010) (190)
- Generation of integration-free neural progenitor cells from cells in human urine (2013) (188)
- Generation of Human Induced Pluripotent Stem Cells from Umbilical Cord Matrix and Amniotic Membrane Mesenchymal Cells* (2010) (175)
- Esrrb Activates Oct4 Transcription and Sustains Self-renewal and Pluripotency in Embryonic Stem Cells* (2008) (164)
- The p53-induced lincRNA-p21 derails somatic cell reprogramming by sustaining H3K9me3 and CpG methylation at pluripotency gene promoters (2014) (158)
- Transcription Activator-like Effector Nuclease (TALEN)-mediated Gene Correction in Integration-free β-Thalassemia Induced Pluripotent Stem Cells* (2013) (157)
- Subcellular Distribution and Cytokine- and Chemokine-regulated Secretion of Leukolysin/MT6-MMP/MMP-25 in Neutrophils* (2001) (151)
- Rescue of ATP7B function in hepatocyte-like cells from Wilson's disease induced pluripotent stem cells using gene therapy or the chaperone drug curcumin. (2011) (151)
- Generating a Non-Integrating Human Induced Pluripotent Stem Cell Bank from Urine-Derived Cells (2013) (150)
- Anti-GPC3-CAR T Cells Suppress the Growth of Tumor Cells in Patient-Derived Xenografts of Hepatocellular Carcinoma (2017) (148)
- Mesenchymal–epithelial transition in development and reprogramming (2019) (147)
- Differential Inhibition of Membrane Type 3 (MT3)-Matrix Metalloproteinase (MMP) and MT1-MMP by Tissue Inhibitor of Metalloproteinase (TIMP)-2 and TIMP-3 Regulates Pro-MMP-2 Activation* (2004) (147)
- Chromatin Accessibility Dynamics during iPSC Reprogramming. (2017) (144)
- Cysteine Array Matrix Metalloproteinase (CA-MMP)/MMP-23 Is a Type II Transmembrane Matrix Metalloproteinase Regulated by a Single Cleavage for Both Secretion and Activation* (2000) (142)
- BMPs functionally replace Klf4 and support efficient reprogramming of mouse fibroblasts by Oct4 alone (2011) (139)
- Oligomerization through Hemopexin and Cytoplasmic Domains Regulates the Activity and Turnover of Membrane-type 1 Matrix Metalloproteinase* (2002) (137)
- Generation of PPARγ mono-allelic knockout pigs via zinc-finger nucleases and nuclear transfer cloning (2011) (136)
- The RNA m6A reader YTHDC1 silences retrotransposons and guards ES cell identity (2021) (124)
- Proprotein Convertase Furin Interacts with and Cleaves Pro-ADAMTS4 (Aggrecanase-1) in the trans-Golgi Network* (2004) (123)
- Nuclear localization of the phosphatidylserine receptor protein via multiple nuclear localization signals. (2004) (118)
- Challenges and advances in clinical applications of mesenchymal stromal cells (2021) (114)
- Stem-like Cancer Cells Are Inducible by Increasing Genomic Instability in Cancer Cells* (2009) (113)
- Generation of tooth-like structures from integration-free human urine induced pluripotent stem cells (2013) (108)
- The oncogene c-Jun impedes somatic cell reprogramming (2015) (107)
- Preliminary evidence from a multicenter prospective observational study of the safety and efficacy of chloroquine for the treatment of COVID-19 (2020) (106)
- Co-recycling of MT1-MMP and MT3-MMP through the Trans-Golgi Network (2004) (105)
- Melanoma Chondroitin Sulfate Proteoglycan Regulates Matrix Metalloproteinase-dependent Human Melanoma Invasion into Type I Collagen* (2001) (103)
- A Dominant-negative Form of Mouse SOX2 Induces Trophectoderm Differentiation and Progressive Polyploidy in Mouse Embryonic Stem Cells* (2007) (101)
- A sequential EMT-MET mechanism drives the differentiation of human embryonic stem cells towards hepatocytes (2017) (100)
- Induced Pluripotent Stem Cells Can Be Used to Model the Genomic Imprinting Disorder Prader-Willi Syndrome* (2010) (100)
- Activation of membrane-type matrix metalloproteinase 3 zymogen by the proprotein convertase furin in the trans-Golgi network. (2002) (99)
- Generation of induced pluripotent stem cell lines from 3 distinct laminopathies bearing heterogeneous mutations in lamin A/C (2011) (97)
- Vitamin C improves the quality of somatic cell reprogramming (2012) (97)
- Regulation of Pluripotency and Reprogramming by Transcription Factors* (2009) (95)
- The Roles of Substrate Thermal Stability and P2 and P1′ Subsite Identity on Matrix Metalloproteinase Triple-helical Peptidase Activity and Collagen Specificity* (2006) (94)
- Lithium, an anti-psychotic drug, greatly enhances the generation of induced pluripotent stem cells (2011) (94)
- The Stem Cell Pluripotency Factor NANOG Activates Transcription with Two Unusually Potent Subdomains at Its C Terminus* (2005) (87)
- Piglets cloned from induced pluripotent stem cells (2012) (86)
- An "attenuator domain" is sandwiched by two distinct transactivation domains in the transcription factor C/EBP (1991) (86)
- Valproic acid‐induced hepatotoxicity in alpers syndrome is associated with mitochondrial permeability transition pore opening‐dependent apoptotic sensitivity in an induced pluripotent stem cell model (2015) (86)
- Fluidic and air-stable supported lipid bilayer and cell-mimicking microarrays. (2008) (77)
- Rational optimization of reprogramming culture conditions for the generation of induced pluripotent stem cells with ultra-high efficiency and fast kinetics (2011) (76)
- Phytomolecule icaritin incorporated PLGA/TCP scaffold for steroid-associated osteonecrosis: Proof-of-concept for prevention of hip joint collapse in bipedal emus and mechanistic study in quadrupedal rabbits (2015) (76)
- VHL inactivation induces HEF1 and Aurora kinase A. (2010) (75)
- PSCA and MUC1 in non-small-cell lung cancer as targets of chimeric antigen receptor T cells (2017) (75)
- Identification of a Nuclear Localization Signal in OCT4 and Generation of a Dominant Negative Mutant by Its Ablation* (2004) (75)
- Membrane type-1 matrix metalloproteinase promotes human melanoma invasion and growth. (2004) (75)
- Reprogramming of mouse and human somatic cells by high‐performance engineered factors (2011) (74)
- Mesothelin is a target of chimeric antigen receptor T cells for treating gastric cancer (2019) (74)
- PRC2 specifies ectoderm lineages and maintains pluripotency in primed but not naïve ESCs (2017) (72)
- Autophagy and mTORC1 regulate the stochastic phase of somatic cell reprogramming (2015) (72)
- Cancer: pathological nuclear reprogramming? (2014) (71)
- Expression, purification and charaterization of recombinant mouse MT5‐MMP protein products (1999) (70)
- Incorporation of a hinge domain improves the expansion of chimeric antigen receptor T cells (2017) (70)
- Design, synthesis, and biological evaluation of novel conformationally constrained inhibitors targeting epidermal growth factor receptor threonine⁷⁹⁰ → methionine⁷⁹⁰ mutant. (2012) (70)
- Transcriptional activation and repression by cellular DNA-binding protein C/EBP (1990) (70)
- Sorting Nexin 10 Induces Giant Vacuoles in Mammalian Cells* (2006) (69)
- Toll-like receptor 2 costimulation potentiates the antitumor efficacy of CAR T Cells (2018) (69)
- Identification of two distinct transactivation domains in the pluripotency sustaining factor nanog (2003) (67)
- Generation of RAG 1- and 2-deficient rabbits by embryo microinjection of TALENs (2013) (66)
- iPS Cells: Mapping the Policy Issues (2009) (66)
- Synthesis of aza-fused polycyclic quinolines through copper-catalyzed cascade reactions. (2010) (65)
- Modeling abnormal early development with induced pluripotent stem cells from aneuploid syndromes. (2012) (65)
- Expression of matrix metalloproteinase‐2 and ‐9 and their inhibitors, tissue inhibitor of metalloproteinase‐1 and ‐2, in primary cultures of human prostatic stromal and epithelial cells * † (2002) (64)
- Intracellular Activation of Human Adamalysin 19/Disintegrin and Metalloproteinase 19 by Furin Occurs via One of the Two Consecutive Recognition Sites* (2002) (63)
- Correction: Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases (2005) (62)
- The mesenchymal-to-epithelial transition in somatic cell reprogramming. (2012) (61)
- Applications of Amniotic Membrane and Fluid in Stem Cell Biology and Regenerative Medicine (2012) (61)
- Chromatin Accessibility Dynamics during Chemical Induction of Pluripotency. (2018) (61)
- Towards an Optimized Culture Medium for the Generation of Mouse Induced Pluripotent Stem Cells* (2010) (60)
- Glis1 facilitates induction of pluripotency via an epigenome–metabolome–epigenome signalling cascade (2020) (60)
- Induced pluripotent stem cell technology in regenerative medicine and biology. (2010) (60)
- CA‐MMP: a matrix metalloproteinase with a novel cysteine array, but without the classic cysteine switch (1999) (60)
- A SNX10/V-ATPase pathway regulates ciliogenesis in vitro and in vivo (2011) (60)
- Transcriptional pause release is a rate-limiting step for somatic cell reprogramming. (2014) (59)
- Resolving Cell Fate Decisions during Somatic Cell Reprogramming by Single-Cell RNA-Seq. (2019) (59)
- Shedding of Membrane Type Matrix Metalloproteinase 5 by a Furin-type Convertase (2001) (58)
- Functional characterization of MT3‐MMP in transfected MDCK cells: progelatinase A activation and tubulogenesis in 3‐D collagen lattice (2000) (56)
- Matrix metalloproteinases target protease-activated receptors on the tumor cell surface. (2005) (56)
- Mitochondrial fusion provides an ‘initial metabolic complementation’ controlled by mtDNA (2015) (55)
- Assembly of indole-2-carboxylic acid esters through a ligand-free copper-catalysed cascade process. (2009) (55)
- RNA Helicase DDX5 Inhibits Reprogramming to Pluripotency by miRNA-Based Repression of RYBP and its PRC1-Dependent and -Independent Functions. (2017) (55)
- Direct activation of pro-matrix metalloproteinase-2 by leukolysin/membrane-type 6 matrix metalloproteinase/matrix metalloproteinase 25 at the asn(109)-Tyr bond. (2003) (53)
- Transposable elements at the center of the crossroads between embryogenesis, embryonic stem cells, reprogramming, and long non-coding RNAs (2015) (52)
- MicroRNAs in somatic cell reprogramming. (2013) (52)
- Mint-3 Regulates the Retrieval of the Internalized Membrane-type Matrix Metalloproteinase, MT5-MMP, to the Plasma Membrane by Binding to Its Carboxyl End Motif EWV* (2004) (51)
- Induced Pluripotent Stem Cells to Model Human Fibrodysplasia Ossificans Progressiva (2015) (50)
- Establishment of peripheral blood mononuclear cell-derived humanized lung cancer mouse models for studying efficacy of PD-L1/PD-1 targeted immunotherapy (2018) (50)
- Srebp‐1 Interacts with c‐Myc to Enhance Somatic Cell Reprogramming (2016) (50)
- Low Immunogenicity of Neural Progenitor Cells Differentiated from Induced Pluripotent Stem Cells Derived from Less Immunogenic Somatic Cells (2013) (49)
- Ribosomal RNA Gene Transcription Mediated by the Master Genome Regulator Protein CCCTC-binding Factor (CTCF) Is Negatively Regulated by the Condensin Complex* (2013) (49)
- Future perspective of induced pluripotent stem cells for diagnosis, drug screening and treatment of human diseases (2010) (49)
- Long-term self-renewal of human pluripotent stem cells on peptide-decorated poly(OEGMA-co-HEMA) brushes under fully defined conditions. (2013) (49)
- Identification of EGFR kinase domain mutations among lung cancer patients in China: implication for targeted cancer therapy (2005) (49)
- The Hemopexin Domain of Membrane-type Matrix Metalloproteinase-1 (MT1-MMP) Is Not Required for Its Activation of proMMP2 on Cell Surface but Is Essential for MT1-MMP-mediated Invasion in Three-dimensional Type I Collagen* (2004) (46)
- Transitions between epithelial and mesenchymal states during cell fate conversions (2014) (46)
- Loss of ATOH8 Increases Stem Cell Features of Hepatocellular Carcinoma Cells. (2015) (46)
- EMT and MET as paradigms for cell fate switching. (2012) (45)
- Rapid inactivation of alpha-1-proteinase inhibitor by neutrophil specific leukolysin/membrane-type matrix metalloproteinase 6. (2004) (45)
- Differentiation of secreted and membrane-type matrix metalloproteinase activities based on substitutions and interruptions of triple-helical sequences. (2007) (45)
- Total synthesis of cyclic tetrapeptide FR235222, a potent immunosuppressant that inhibits mammalian histone deacetylases. (2005) (45)
- SETDB1-Mediated Cell Fate Transition between 2C-Like and Pluripotent States. (2020) (45)
- Modeling of hemophilia A using patient-specific induced pluripotent stem cells derived from urine cells. (2014) (45)
- Simple and versatile synthetic polydopamine-based surface supports reprogramming of human somatic cells and long-term self-renewal of human pluripotent stem cells under defined conditions. (2016) (44)
- Differentiation of mouse embryonic stem cells into dental epithelial-like cells induced by ameloblasts serum-free conditioned medium. (2010) (42)
- Failure to replicate the STAP cell phenomenon (2015) (42)
- Models of global gene expression define major domains of cell type and tissue identity (2017) (42)
- Cyclin-dependent Kinase-mediated Sox2 Phosphorylation Enhances the Ability of Sox2 to Establish the Pluripotent State* (2015) (41)
- Overexpression of matrix metalloproteinases leads to lethality in transgenic Xenopus laevis: Implications for tissue‐dependent functions of matrix metalloproteinases during late embryonic development (2001) (40)
- Characterization and generation of human definitive multipotent hematopoietic stem/progenitor cells (2020) (39)
- Distinct Roles of Catalytic and Pexin-like Domains in Membrane-type Matrix Metalloproteinase (MMP)-mediated Pro-MMP-2 Activation and Collagenolysis* (2003) (39)
- Mouse Meningiocytes Express Sox2 and Yield High Efficiency of Chimeras after Nuclear Reprogramming with Exogenous Factors* (2008) (39)
- Quantitative evaluation of the immunodeficiency of a mouse strain by tumor engraftments (2015) (38)
- Direct generation of ES-like cells from unmodified mouse embryonic fibroblasts by Oct4/Sox2/Myc/Klf4 (2007) (36)
- In vitro culture and directed osteogenic differentiation of human pluripotent stem cells on peptides-decorated two-dimensional microenvironment. (2015) (35)
- ANGPTL7 regulates the expansion and repopulation of human hematopoietic stem and progenitor cells (2015) (34)
- The function and regulation of mesenchymal-to-epithelial transition in somatic cell reprogramming. (2014) (34)
- Deficiency in class III PI3-kinase confers postnatal lethality with IBD-like features in zebrafish (2018) (33)
- Icaritin, an Exogenous Phytomolecule, Enhances Osteogenesis but Not Angiogenesis—An In Vitro Efficacy Study (2012) (33)
- RNA Helicase DDX5 Inhibits Reprogramming to Pluripotency by miRNA-Based Repression of RYBP and its PRC1-Dependent and -Independent Functions. (2017) (33)
- Increased aggressiveness of human prostate PC-3 tumor cells expressing cell surface localized membrane type-1 matrix metalloproteinase (MT1-MMP). (2009) (33)
- Induction of Pluripotent Stem Cells from Mouse Embryonic Fibroblasts by Jdp2-Jhdm1b-Mkk6-Glis1-Nanog-Essrb-Sall4. (2019) (33)
- Sorting Nexin 33 Induces Mammalian Cell Micronucleated Phenotype and Actin Polymerization by Interacting with Wiskott-Aldrich Syndrome Protein* (2009) (32)
- The C-terminal Pentapeptide of Nanog Tryptophan Repeat Domain Interacts with Nac1 and Regulates Stem Cell Proliferation but Not Pluripotency* (2009) (32)
- Porcine induced pluripotent stem cells may bridge the gap between mouse and human iPS (2010) (32)
- Therapeutic developments in matrix metalloproteinase inhibition (2002) (31)
- The magic of four: induction of pluripotent stem cells from somatic cells by Oct4, Sox2, Myc and Klf4 (2007) (31)
- JMJD3 and UTX determine fidelity and lineage specification of human neural progenitor cells (2020) (30)
- Factor-induced Reprogramming and Zinc Finger Nuclease-aided Gene Targeting Cause Different Genome Instability in β-Thalassemia Induced Pluripotent Stem Cells (iPSCs)* (2015) (29)
- Kdm2b Regulates Somatic Reprogramming through Variant PRC1 Complex-Dependent Function. (2017) (29)
- GATA2−/− human ESCs undergo attenuated endothelial to hematopoietic transition and thereafter granulocyte commitment (2015) (29)
- Pyrimido[4,5-d]pyrimidin-4(1H)-one derivatives as selective inhibitors of EGFR threonine790 to methionine790 (T790M) mutants. (2013) (29)
- Vitamin C–dependent lysine demethylase 6 (KDM6)-mediated demethylation promotes a chromatin state that supports the endothelial-to-hematopoietic transition (2019) (28)
- BMI1 enables interspecies chimerism with human pluripotent stem cells (2018) (27)
- Transient Activation of Mitoflashes Modulates Nanog at the Early Phase of Somatic Cell Reprogramming. (2016) (27)
- Short-Term Mitochondrial Permeability Transition Pore Opening Modulates Histone Lysine Methylation at the Early Phase of Somatic Cell Reprogramming. (2018) (26)
- Gadd45a is a heterochromatin relaxer that enhances iPS cell generation (2016) (24)
- Characterization of a novel cell penetrating peptide derived from human Oct4 (2014) (24)
- Heterochromatin loosening by the Oct4 linker region facilitates Klf4 binding and iPSC reprogramming (2020) (24)
- Urine as a source of stem cells. (2013) (23)
- The propensity for tumorigenesis in human induced pluripotent stem cells is related with genomic instability (2013) (23)
- Stem cell science on the rise in China. (2012) (23)
- Regulation of MT1‐MMP activity by β‐catenin in MDCK non‐cancer and HT1080 cancer cells (2010) (23)
- Atovaquone derivatives as potent cytotoxic and apoptosis inducing agents. (2009) (23)
- DNAX-activating protein 10 co-stimulation enhances the anti-tumor efficacy of chimeric antigen receptor T cells (2018) (22)
- Passive DNA demethylation preferentially up-regulates pluripotency-related genes and facilitates the generation of induced pluripotent stem cells (2017) (22)
- Myeloid-derived suppressor cells promote lung cancer metastasis by CCL11 to activate ERK and AKT signaling and induce epithelial-mesenchymal transition in tumor cells (2021) (21)
- IL-6 trans-signaling promotes the expansion and anti-tumor activity of CAR T cells (2020) (21)
- BMP4 resets mouse epiblast stem cells to naive pluripotency through ZBTB7A/B-mediated chromatin remodelling (2020) (21)
- Structure of Sorting Nexin 11 (SNX11) Reveals a Novel Extended Phox Homology (PX) Domain Critical for Inhibition of SNX10-induced Vacuolation* (2013) (20)
- Lysine-specific histone demethylase 1 inhibition promotes reprogramming by facilitating the expression of exogenous transcriptional factors and metabolic switch (2016) (20)
- Loss of Angiopoietin-like 7 diminishes the regeneration capacity of hematopoietic stem and progenitor cells (2015) (20)
- An antiapoptotic role of sorting nexin 7 is required for liver development in zebrafish (2012) (20)
- SNX16 Regulates the Recycling of E-Cadherin through a Unique Mechanism of Coordinated Membrane and Cargo Binding. (2017) (20)
- Metabolic switch and epithelial–mesenchymal transition cooperate to regulate pluripotency (2020) (20)
- Dynamically reorganized chromatin is the key for the reprogramming of somatic cells to pluripotent cells (2015) (19)
- A Virus-Infected, Reprogrammed Somatic Cell–Derived Tumor Cell (VIReST) Vaccination Regime Can Prevent Initiation and Progression of Pancreatic Cancer (2019) (18)
- Neural progenitor cells from human induced pluripotent stem cells generated less autogenous immune response (2014) (17)
- Immediate expression of Cdh2 is essential for efficient neural differentiation of mouse induced pluripotent stem cells. (2013) (17)
- The magic continues for the iPS strategy (2008) (17)
- Human Embryo Editing: Opportunities and Importance of Transnational Cooperation. (2017) (17)
- miR-204–containing exosomes ameliorate GVHD-associated dry eye disease (2022) (17)
- A high-level mammalian expression system based on the Madin-Darby canine kidney cell line. (1998) (17)
- Lower genomic stability of induced pluripotent stem cells reflects increased non-homologous end joining (2018) (17)
- GZD824 suppresses the growth of human B cell precursor acute lymphoblastic leukemia cells by inhibiting the SRC kinase and PI3K/AKT pathways (2016) (17)
- Application of iPS Cells in Dental Bioengineering and Beyond (2014) (17)
- Roles of small molecules in somatic cell reprogramming (2013) (16)
- Somatic cell reprogramming for regenerative medicine: SCNT vs. iPS cells (2012) (16)
- A reciprocal antagonism between miR‐376c and TGF‐β signaling regulates neural differentiation of human pluripotent stem cells (2014) (16)
- Rapid generation of ACE2 humanized inbred mouse model for COVID-19 with tetraploid complementation (2020) (16)
- Sequential EMT-MET induces neuronal conversion through Sox2 (2017) (16)
- Aromatic Residues in the C-terminal Domain 2 Are Required for Nanog to Mediate LIF-independent Self-renewal of Mouse Embryonic Stem Cells* (2008) (16)
- SNX17 regulates Notch pathway and pancreas development through the retromer-dependent recycling of Jag1 (2012) (16)
- JMJD3 acts in tandem with KLF4 to facilitate reprogramming to pluripotency (2020) (15)
- Transplanted motoneurons derived from human induced pluripotent stem cells form functional connections with target muscle. (2013) (15)
- Chemical reprogramming of mouse embryonic and adult fibroblast into endoderm lineage (2017) (15)
- Reprogramming somatic cells to cells with neuronal characteristics by defined medium both in vitro and in vivo (2015) (14)
- Class IIa Histone Deacetylases and Myocyte Enhancer Factor 2 Proteins Regulate the Mesenchymal-to-Epithelial Transition of Somatic Cell Reprogramming* (2013) (14)
- Remission for Loss of Odontogenic Potential in a New Micromilieu In Vitro (2016) (14)
- TGFβ signaling regulates the choice between pluripotent and neural fates during reprogramming of human urine derived cells (2016) (14)
- Sorting Nexin 11 Regulates Lysosomal Degradation of Plasma Membrane TRPV3 (2016) (14)
- Heterogeneity of CD34 and CD38 expression in acute B lymphoblastic leukemia cells is reversible and not hierarchically organized (2016) (14)
- Bioethics in China: No wild east (2016) (13)
- Limited processing of pro-matrix metalloprotease-2 (gelatinase A) overexpressed by transfection in PC-3 human prostate tumor cells: association with restricted cell surface localization of membrane-type matrix metalloproteinase-1. (2004) (11)
- Structure of human SNX10 reveals insights into its role in human autosomal recessive osteopetrosis (2014) (11)
- A new diaryl urea compound, D181, induces cell cycle arrest in the G1 and M phases by targeting receptor tyrosine kinases and the microtubule skeleton (2012) (11)
- Chromatin accessibility dynamics during cell fate reprogramming (2021) (11)
- The E3 Ligase MIB1 Promotes Proteasomal Degradation of NRF2 and Sensitizes Lung Cancer Cells to Ferroptosis (2021) (10)
- Complete Restoration of Cell Surface Activity of Transmembrane-truncated MT1-MMP by a Glycosylphosphatidylinositol Anchor (2007) (10)
- SNX17 Recruits USP9X to Antagonize MIB1-Mediated Ubiquitination and Degradation of PCM1 during Serum-Starvation-Induced Ciliogenesis (2019) (10)
- SNX16 negatively regulates the migration and tumorigenesis of MCF-7 cells (2013) (9)
- Genome-wide CNV analysis in mouse induced pluripotent stem cells reveals dosage effect of pluripotent factors on genome integrity (2014) (9)
- Generation of tooth–periodontium complex structures using high-odontogenic potential dental epithelium derived from mouse embryonic stem cells (2017) (9)
- An efficient and tunable route to AG7088, a rhinovirus protease inhibitor (2004) (9)
- Hemi-methylated CpG sites connect Dnmt1-knockdown-induced and Tet1-induced DNA demethylation during somatic cell reprogramming (2019) (8)
- Serum metalloproteinase leukolysin (MMP‐25/MT‐6): a potential metabolic marker for atopy‐associated inflammation (2010) (8)
- Zfyve9a regulates the proliferation of hepatic cells during zebrafish embryogenesis. (2013) (8)
- Amniotic Stem Cells: Potential in Regenerative Medicine (2012) (8)
- Naloxone regulates the differentiation of neural stem cells via a receptor‐independent pathway (2020) (8)
- Where cell fate conversions meet Chinese philosophy (2014) (8)
- Stem cell aging in adult progeria (2015) (7)
- An Efficient Synthesis of ABT-263, a Novel Inhibitor of Antiapoptotic Bcl-2 Proteins (2008) (7)
- SS18 regulates pluripotent-somatic transition through phase separation (2021) (7)
- PX domain and CD domain play different roles in localization and vacuolation of Sorting Nexin 10 (2009) (7)
- Short-Term Mitochondrial Permeability Transition Pore Opening Modulates Histone Lysine Methylation at the Early Phase of Somatic Cell Reprogramming. (2019) (6)
- Insight into the maintenance of odontogenic potential in mouse dental mesenchymal cells based on transcriptomic analysis (2016) (6)
- Order from chaos: single cell reprogramming in two phases. (2012) (6)
- Treatment and Prevention of Lung Cancer Using a Virus-Infected Reprogrammed Somatic Cell-Derived Tumor Cell Vaccination (VIReST) Regime (2020) (6)
- UBE2O and USP7 co‐regulate RECQL4 ubiquitinylation and homologous recombination‐mediated DNA repair (2021) (6)
- Proteins in DNA methylation and their role in neural stem cell proliferation and differentiation (2021) (6)
- The efficacy and safety of CAR-T cell therapy in patients with refractory ALL and concomitant HBV infection (2020) (5)
- CD215+ Myeloid Cells Respond to Interleukin 15 Stimulation and Promote Tumor Progression (2017) (5)
- Deubiquitylating Nanog: novel role of USP21 in embryonic stem cell maintenance (2017) (5)
- Reprogramming in suspension (2012) (5)
- Copper(I) Iodide Catalyzed DominoProcess to Quinazolin-4(3H)-ones (2008) (5)
- Defined, serum/feeder-free conditions for expansion and drug screening of primary B-acute lymphoblastic leukemia (2017) (5)
- Induced pluripotent stem cell (iPS) technology: promises and challenges (2009) (5)
- Resolution of Reprogramming Transition States by Single Cell RNA-Sequencing (2017) (4)
- Forkhead box family transcription factors as versatile regulators for cellular reprogramming to pluripotency (2021) (4)
- The Battle between TET Proteins and DNA Methylation for the Right Cell. (2018) (4)
- Characterization of a novel cell penetrating peptide derived from human Oct4 (2014) (4)
- Gadd45a opens up the promoter regions of miR-295 facilitating pluripotency induction (2017) (4)
- The homeobox transcription factor MSX2 partially mediates the effects of bone morphogenetic protein 4 (BMP4) on somatic cell reprogramming (2018) (4)
- Evaluation of CML TKI Induced Cardiovascular Toxicity and Development of Potential Rescue Strategies in a Zebrafish Model (2021) (3)
- Membrane-type Matrix Metalloproteinase 5 (2004) (3)
- Epigenetic Landmarks During Somatic Reprogramming (2016) (3)
- Cell regeneration- bridging discoveries in applied and basic research (2012) (3)
- Pluripotency without Proliferation (2016) (3)
- Aromatic residues in the C-terminal domain 2 are required for Nanog to mediate LIF-independent self-renewal of mouse embryonic stem cells. VOLUME 283 (2008) PAGES 4480-4489 (2009) (3)
- Verified the effectiveness of AsCpf1 system in a variety of vertebrate species (2018) (3)
- Copper(I) Iodide Catalyzed Domino Process to Quinazolin-4(3H)-ones. (2009) (3)
- Enhanced replication of SARS-CoV-2 Omicron BA.2 in human forebrain and midbrain organoids (2022) (3)
- Reprogramming mouse embryonic fibroblasts using different reprogramming factors (2015) (2)
- C3aR costimulation enhances the antitumor efficacy of CAR-T cell therapy through Th17 expansion and memory T cell induction (2022) (2)
- A Room-Temperature, Copper-Catalyzed Cascade Process for Diethyl 2-Aryl-3,4-dihydro-4-oxo-1,1(2H)-naphthalenedicarboxylate (2010) (2)
- Human induced-T-to-natural killer cells have potent anti-tumour activities (2022) (2)
- Assembly of Indole‐2‐carboxylic Acid Esters Through a Ligand‐Free Copper‐Catalyzed Cascade Process. (2010) (2)
- Modulation of HDAC Activity Directly Reprogramme Embryonic Stem Cell to Trophoblast Stem Cell (2022) (2)
- Single cell atlas of developing mouse dental germs reveals populations of CD24+ and Plac8+ odontogenic cells. (2022) (2)
- The N-terminal domain is a transcriptional activation domain required for Nanog to maintain ES cell self-renewal (2009) (2)
- Nuclear reprogramming and the cancer genome (2013) (2)
- Mesenchymal–epithelial transition in development and reprogramming (2019) (2)
- Efficient induction of neural progenitor cells from human ESC/iPSCs on Type I Collagen (2021) (2)
- Membrane-type Matrix Metalloproteinase 6 (2004) (2)
- Rejuvenation of &bgr; cells by epigenetic editing (2018) (1)
- An Efficient and Tunable Route to AG7088, a Rhinovirus Protease Inhibitor. (2005) (1)
- A Novel CCK Receptor GPR173 Mediates Potentiation of GABAergic Inhibition (2023) (1)
- Hierarchical deployment of Tbx3 dictates the identity of hypothalamic KNDy neurons to control puberty onset (2022) (1)
- SNX17 regulates Notch pathway and pancreas development through the retromer-dependent recycling of Jag1 (2012) (1)
- MAP2K6 remodels chromatin and facilitates reprogramming by activating Gatad2b-phosphorylation dependent heterochromatin loosening (2021) (1)
- Expression and purification of membrane-type MMPs. (2010) (1)
- MYOCD is Required for Cardiomyocyte-like Cells Induction from Human Urine Cells and Fibroblasts Through Remodeling Chromatin (2022) (1)
- Effects of cholic acid modified glucosamine on chondrogenic differentiation (2016) (1)
- Corrigendum: The oncogene c-Jun impedes somatic cell reprogramming (2015) (1)
- Genome-wide CNV analysis in mouse induced pluripotent stem cells reveals dosage effect of pluripotent factors on genome integrity (2014) (1)
- Low-dose AAV-CRISPR-mediated liver-specific knock-in restored hemostasis in neonatal hemophilia B mice with subtle antibody response (2022) (1)
- Corrigendum: Failure to replicate the STAP cell phenomenon (2015) (1)
- Cancer stem cells: advances in biology and clinical translation-a Keystone Symposia report. (2021) (1)
- Embigin facilitates monocarboxylate transporter 1 localization to the plasma membrane and transition to a decoupling state. (2022) (1)
- BMP4 drives primed to naïve transition through PGC-like state (2022) (1)
- The cell biology of embryonic stem cells (2008) (1)
- The nuclear factor CECR2 promotes somatic cell reprogramming by reorganizing the chromatin structure (2020) (1)
- Reprogramming mouse embryonic fibroblasts using different systems (2015) (1)
- The Battle between TET Proteins and DNA Methylation for the Right Cell: (Trends in Cell Biology 28, 973-975, 2018). (2019) (1)
- Why it is important to study human–monkey embryonic chimeras in a dish (2022) (1)
- 2008: year of the rat for stem cell research (2009) (1)
- H3K27ac mediated SS18/BAFs relocation regulates JUN induced pluripotent-somatic transition (2022) (1)
- Looking Back: Epigenomics. (2017) (1)
- Generation of mitochondria-rich kidney organoids from expandable intermediate mesoderm progenitors reprogrammed from human urine cells under defined medium (2022) (1)
- Generation of tooth-like structures from integration-free human urine induced pluripotent stem cells (2013) (1)
- Matrix metalloproteinase 23 (2004) (1)
- Leukolysin, a potential marker for airway remodeling in asthma (2005) (1)
- The Art of Reprogramming for Regenerative Medicine (2022) (0)
- Copper-Catalyzed Synthesis of Indole-2-carboxylates (2010) (0)
- IUPHAR 2006--15th World Congress of Pharmacology. Metalloproteinases as Therapeutical Targets for Cancer Therapy. 2-7 July 2006, Beijing, China. (2006) (0)
- The RNA m6A reader YTHDC1 silences retrotransposons and guards ES cell identity (2021) (0)
- Generation of tooth–periodontium complex structures using high-odontogenic potential dental epithelium derived from mouse embryonic stem cells (2017) (0)
- Cryo-EM structures of kalium channelrhodopsins KCRs (2022) (0)
- Species-specific rewiring of definitive endoderm developmental gene activation via endogenous retroviruses through TET1-mediated demethylation. (2022) (0)
- Regeneration of the human segmentation clock in somitoids in vitro (2022) (0)
- Cell regeneration- bridging discoveries in applied and basic research (2012) (0)
- Neural progenitor cells from human induced pluripotent stem cells generated less autogenous immune response (2014) (0)
- Valproic Acid-induced Hepatotoxicity in Alpers Syndrome is Associated with mPTP Opening Dependent Apoptotic Sensitivity in an iPSC Model (2015) (0)
- Retinoic acid stimulation of gelatinase a (MMP-2) and matrilysin (MMP-7) expression in human prostate epithelial cells (2003) (0)
- Editorial Amniotic Stem Cells: Potential in Regenerative Medicine (2012) (0)
- Transitions between epithelial and mesenchymal states during cell fate conversions (2014) (0)
- A novel metalloproteinase, leukolysin, and development of a standardized immunoassay☆ (2004) (0)
- Identification of New Transcription Factors that Can Promote Pluripotent Reprogramming (2021) (0)
- In grateful recognition of our Editorial Board (2016) (0)
- In their words (2008) (0)
- Hypoproliferative human NPC xenografts survived extendedly in the brain of immunocompetent rats (2020) (0)
- Glis1 facilitates induction of pluripotency via an epigenome–metabolome–epigenome signalling cascade (2020) (0)
- BMP4 resets mouse epiblast stem cells to naive pluripotency through ZBTB7A/B-mediated chromatin remodelling (2020) (0)
- Chapter 168 – Membrane-type Matrix Metalloproteinase 5 (2013) (0)
- Corrigendum: Hallmarks of pluripotency (2015) (0)
- nprot.2012.115 (2014) (0)
- Reprogramming somatic cells to cells with neuronal characteristics by defined medium both in vitro and in vivo (2015) (0)
- [Culture of pluripotent stem cell-derived hepatocytes and organoids]. (2022) (0)
- Correction to: MAP2K6 remodels chromatin and facilitates reprogramming by activating Gatad2b-phosphorylation dependent heterochromatin loosening (2021) (0)
- Research Highlight The Mighty Mice Prove Pluripotency for iPSCs (2010) (0)
- Hemi-methylated CpG sites connect Dnmt1-knockdown-induced and Tet1-induced DNA demethylation during somatic cell reprogramming (2019) (0)
- Reprogramming of mouse and human somatic cells by high‐performance engineered factors (2011) (0)
- New serum-free medium for the rapid induction of high efficiency of pluripotent stem cells, and method of use thereof (2009) (0)
- Vitamin C and epigenetic regulation (2014) (0)
- GATA2−/− human ESCs undergo attenuated endothelial to hematopoietic transition and thereafter granulocyte commitment (2015) (0)
- Mutations of nuclear localization signals in mNANOG generate dominant negative mutants (2009) (0)
- 1430CRISPR/Cas9-mediated correction of Troponin I R186Q mutation rescues myofibrillar disarray and excitation-contraction coupling abnormalities in IPSC model from hypertrophic cardiomyopathy patient (2018) (0)
- Copper-Catalyzed Synthesis of Aza-Fused Polycyclic Quinolines (2010) (0)
- Mechanism underlying delayed rectifying in human voltage-mediated activation Eag2 channel (2023) (0)
- A protocol for generating human induced pluripotent stem cells from urine samples (2012) (0)
- Single Cell Sequencing Reveals Early PGC-like Intermediates During Mouse Primed to Naïve Transition (2021) (0)
- Fast and Efficient Mouse Pluripotency Reprogramming Using a Chemically-Defined Medium (2022) (0)
- Immobilization of oriented protein molecules on poly(ethylene glycol)‐coated Si(111) (vol. 4, Issue 7, pp. 1965‐1976) (2004) (0)
- AP-1 activity is a major barrier of human somatic cell reprogramming (2021) (0)
- Human induced-T-to-natural killer cells have potent anti-tumour activities (2022) (0)
- Phase separating cell fate. (2021) (0)
- SNX16 negatively regulates the migration and tumorigenesis of MCF-7 cells (2013) (0)
- JMJD3 and UTX determine fidelity and lineage specification of human neural progenitor cells (2020) (0)
- Title Generation of integration-free neural progenitor cells from cellsin human urine (2013) (0)
- Establishment of porcine and human expanded potential stem cells (2019) (0)
- Hypoproliferative human neural progenitor cell xenografts survived extendedly in the brain of immunocompetent rats (2021) (0)
- Additional file 3: Figure S3. of Incorporation of a hinge domain improves the expansion of chimeric antigen receptor T cells (2017) (0)
- Single-cell RNA sequencing reveals the developmental program underlying proximal–distal patterning of the human lung at the embryonic stage (2023) (0)
- The mighty mice prove pluripotency for iPSCs. (2010) (0)
- How can a skin cell become a nerve cell (2017) (0)
- ZBTB7A regulates primed-to-naïve transition of pluripotent stem cells via recognition of the PNT-associated sequence by Zinc Fingers 1-2 and recognition of γ-globin -200 gene element by Zinc Fingers 1-4. (2023) (0)
- Additional file 2: Figure S2. of Incorporation of a hinge domain improves the expansion of chimeric antigen receptor T cells (2017) (0)
- Correction: Passive DNA demethylation preferentially up-regulates pluripotency-related genes and facilitates the generation of induced pluripotent stem cells (2022) (0)
- Stem cell aging in adult progeria (2015) (0)
- Regulation of MT‐MMP trafficking by Intracellular Effectors (2006) (0)
- Mitochondrial fusion provides an ‘initial metabolic complementation’ controlled by mtDNA (2015) (0)
- Chapter 174 – Matrix Metalloproteinase 23 (2013) (0)
- Characterization and generation of human definitive multipotent hematopoietic stem/progenitor cells (2020) (0)
- Comparison of Leukolysin/MT6-MMP in Bronchoalveolar Lavage Fluid from Lung Transplant Patients and Asthmatics (2006) (0)
- Hypoproliferative human neural progenitor cell xenografts survived extendedly in the brain of immunocompetent rats (2021) (0)
- Author Correction: Glis1 facilitates induction of pluripotency via an epigenome–metabolome–epigenome signalling cascade (2020) (0)
- Correction: A Virus-infected, Reprogrammed Somatic Cell–derived Tumor Cell (VIReST) Vaccination Regime can Prevent Initiation and Progression of Pancreatic Cancer (2021) (0)
- Mouse embryonic stem cells resist c-Jun induced differentiation when in suspension (2018) (0)
- Mechanism of physical force induced human slack channel desensitization (2023) (0)
- Deficiency in class III PI3-kinase confers postnatal lethality with IBD-like features in zebrafish (2018) (0)
- BMI1 enables interspecies chimerism with human pluripotent stem cells (2018) (0)
- Leukolysin and Asthma (2006) (0)
- Chapter 169 – Membrane-type Matrix Metalloproteinase 6 (2013) (0)
- Three-dimensional molecular architecture of mouse organogenesis (2022) (0)
- PRC2 specifies ectoderm lineages and maintains pluripotency in primed but not naïve ESCs (2017) (0)
- anti-psychotic drug, enhances the generation of induced pluripotent stem cells. (2011) (0)
- H3K27ac mediated SS18/BAFs relocation regulates JUN induced pluripotent-somatic transition (2022) (0)
- Targeting G-quadruplex for rescuing impaired chondrogenesis in WRN-deficient stem cells (2022) (0)
- Application of iPS Cells in Dental Bioengineering and Beyond (2014) (0)
- Identification of a group of bisbenzylisoquinoline (BBIQ) compounds as ferroptosis inhibitors (2022) (0)
- A Room‐Temperature, Copper‐Catalyzed Cascade Process for Diethyl 2‐Aryl‐3,4‐dihydro‐4‐oxo‐1,1(2H)‐naphthalenedicarboxylate. (2011) (0)
- What controls organ regeneration (2017) (0)
- Nerve regeneration by interferon intervention in aging brain (2023) (0)
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