Dun‐ Xian Tan
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(Suggest an Edit or Addition)Dun‐ Xian Tan's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- One molecule, many derivatives: A never‐ending interaction of melatonin with reactive oxygen and nitrogen species? (2007) (1459)
- Melatonin as an antioxidant: under promises but over delivers (2016) (1000)
- Melatonin as a natural ally against oxidative stress: a physicochemical examination (2011) (993)
- Chemical and physical properties and potential mechanisms: melatonin as a broad spectrum antioxidant and free radical scavenger. (2002) (987)
- Actions of melatonin in the reduction of oxidative stress. A review. (2000) (952)
- Extrapineal melatonin: sources, regulation, and potential functions (2014) (732)
- Melatonin: an ancient molecule that makes oxygen metabolically tolerable (2015) (713)
- The chemistry of melatonin's interaction with reactive species (2003) (712)
- On the free radical scavenging activities of melatonin's metabolites, AFMK and AMK (2013) (687)
- Biochemical reactivity of melatonin with reactive oxygen and nitrogen species (2007) (592)
- Melatonin as an antioxidant: biochemical mechanisms and pathophysiological implications in humans. (2003) (576)
- Melatonin: a multitasking molecule. (2010) (554)
- Significance of Melatonin in Antioxidative Defense System: Reactions and Products (2000) (538)
- Melatonin: a hormone, a tissue factor, an autocoid, a paracoid, and an antioxidant vitamin (2003) (520)
- Melatonin mitigates mitochondrial malfunction (2005) (517)
- Effects of Melatonin Treatment in Septic Newborns (2001) (496)
- Melatonin, hydroxyl radical‐mediated oxidative damage, and aging: A hypothesis (1993) (479)
- Functional roles of melatonin in plants, and perspectives in nutritional and agricultural science. (2012) (469)
- Kynuramines, metabolites of melatonin and other indoles: the resurrection of an almost forgotten class of biogenic amines (2009) (453)
- The significance of the metabolism of the neurohormone melatonin: Antioxidative protection and formation of bioactive substances (1993) (444)
- Melatonin directly scavenges hydrogen peroxide: a potentially new metabolic pathway of melatonin biotransformation. (2000) (439)
- Melatonin and Its Relation to the Immune System and Inflammation (2000) (429)
- Melatonin: reducing the toxicity and increasing the efficacy of drugs (2002) (428)
- Melatonin: exceeding expectations. (2014) (426)
- Mitochondria and chloroplasts as the original sites of melatonin synthesis: a hypothesis related to melatonin's primary function and evolution in eukaryotes (2013) (423)
- Melatonin as a Potent and Inducible Endogenous Antioxidant: Synthesis and Metabolism (2015) (398)
- Free Radical‐Mediated Molecular Damage (2001) (396)
- Melatonin As a Free Radical Scavenger: Implications for Aging and Age‐Related Diseases a (1994) (385)
- Melatonin, the circadian multioscillator system and health: the need for detailed analyses of peripheral melatonin signaling (2012) (379)
- Comparative physiological, metabolomic, and transcriptomic analyses reveal mechanisms of improved abiotic stress resistance in bermudagrass [Cynodon dactylon (L). Pers.] by exogenous melatonin (2014) (379)
- Melatonin—A Highly Potent Endogenous Radical Scavenger and Electron Donor: New Aspects of the Oxidation Chemistry of this Indole Accessed in vitro a (1994) (370)
- A novel melatonin metabolite, cyclic 3-hydroxymelatonin: a biomarker of in vivo hydroxyl radical generation. (1998) (368)
- Protective effects of melatonin in reducing oxidative stress and in preserving the fluidity of biological membranes: a review (2014) (365)
- Melatonin and the ovary: physiological and pathophysiological implications. (2009) (364)
- Melatonin and Reproduction Revisited (2009) (356)
- Melatonin and its metabolites: new findings regarding their production and their radical scavenging actions. (2007) (353)
- Identification of highly elevated levels of melatonin in bone marrow: its origin and significance. (1999) (344)
- Melatonin as a mitochondria-targeted antioxidant: one of evolution’s best ideas (2017) (341)
- Nuclear localization of melatonin in different mammalian tissues: Immunocytochemical and radioimmunoassay evidence (1993) (337)
- Melatonin in walnuts: influence on levels of melatonin and total antioxidant capacity of blood. (2005) (334)
- Cardiovascular diseases: protective effects of melatonin (2007) (329)
- High levels of melatonin in the seeds of edible plants: possible function in germ tissue protection. (2000) (327)
- Melatonin and mitochondrial function. (2004) (321)
- The pineal hormone melatonin inhibits DNA-adduct formation induced by the chemical carcinogen safrole in vivo. (1993) (321)
- Medical implications of melatonin: receptor-mediated and receptor-independent actions. (2007) (317)
- Actions of Melatonin in the Reduction of Oxidative Stress (2000) (314)
- Melatonin, a Full Service Anti-Cancer Agent: Inhibition of Initiation, Progression and Metastasis (2017) (312)
- Melatonin: a novel protective agent against oxidative injury of the ischemic/reperfused heart. (2003) (307)
- Anti-inflammatory actions of melatonin and its metabolites, N1-acetyl-N2-formyl-5-methoxykynuramine (AFMK) and N1-acetyl-5-methoxykynuramine (AMK), in macrophages (2005) (305)
- Phytomelatonin: a review. (2009) (302)
- Melatonin and cell death: differential actions on apoptosis in normal and cancer cells (2003) (299)
- Melatonin as a radioprotective agent: a review. (2004) (299)
- Melatonin: An Established Antioxidant Worthy of Use in Clinical Trials (2009) (298)
- The changing biological roles of melatonin during evolution: from an antioxidant to signals of darkness, sexual selection and fitness (2009) (290)
- Causes of Oxidative Stress in the Pre- and Perinatal Period (2002) (289)
- Significance and application of melatonin in the regulation of brown adipose tissue metabolism: relation to human obesity (2011) (287)
- Clinical uses of melatonin: evaluation of human trials. (2010) (287)
- Melatonin mediates the regulation of ABA metabolism, free-radical scavenging, and stomatal behaviour in two Malus species under drought stress. (2015) (287)
- Pharmacology and Physiology of Melatonin in the Reduction of Oxidative Stress in vivo (2000) (284)
- The Oxidant/Antioxidant Network: Role of Melatonin (1999) (277)
- Both physiological and pharmacological levels of melatonin reduce DNA adduct formation induced by the carcinogen safrole. (1994) (275)
- Phytomelatonin: Assisting Plants to Survive and Thrive (2015) (273)
- N1‐acetyl‐N2‐formyl‐5‐methoxykynuramine, a biogenic amine and melatonin metabolite, functions as a potent antioxidant (2001) (268)
- Alzheimer’s disease: pathological mechanisms and the beneficial role of melatonin (2012) (255)
- Melatonin biosynthesis in plants: multiple pathways catalyze tryptophan to melatonin in the cytoplasm or chloroplasts (2016) (254)
- Melatonin in Chinese medicinal herbs. (2003) (254)
- Melatonin in plants. (2009) (254)
- Melatonin: A Mitochondrial Targeting Molecule Involving Mitochondrial Protection and Dynamics (2016) (252)
- Melatonin and pregnancy in the human. (2008) (252)
- Antioxidant properties of the melatonin metabolite N1-acetyl-5-methoxykynuramine (AMK): scavenging of free radicals and prevention of protein destruction (2003) (248)
- High physiological levels of melatonin in the bile of mammals. (1999) (240)
- The universal nature, unequal distribution and antioxidant functions of melatonin and its derivatives. (2013) (238)
- Detection and quantification of the antioxidant melatonin in Montmorency and Balaton tart cherries (Prunus cerasus). (2001) (231)
- Mitochondria: Central Organelles for Melatonin′s Antioxidant and Anti-Aging Actions (2018) (228)
- Melatonin delays leaf senescence and enhances salt stress tolerance in rice (2015) (226)
- Melatonin and stable circadian rhythms optimize maternal, placental and fetal physiology. (2014) (222)
- Basic mechanisms involved in the anti-cancer effects of melatonin. (2010) (216)
- Reactive oxygen and nitrogen species and cellular and organismal decline: amelioration with melatonin (2002) (215)
- Melatonin as an antioxidant: physiology versus pharmacology (2005) (207)
- Melatonin and its potential biological functions in the fruits of sweet cherry (2013) (204)
- Circadian rhythm abnormalities of melatonin in Smith-Magenis syndrome (2000) (204)
- Light at night, chronodisruption, melatonin suppression, and cancer risk: a review. (2007) (203)
- Individual and synergistic antioxidative actions of melatonin: studies with vitamin E, vitamin C, glutathione and desferrrioxamine (desferoxamine) in rat liver homogenates (2001) (202)
- Pharmacological utility of melatonin in reducing oxidative cellular and molecular damage. (2004) (202)
- Obesity and metabolic syndrome: Association with chronodisruption, sleep deprivation, and melatonin suppression (2012) (202)
- Mechanistic and comparative studies of melatonin and classic antioxidants in terms of their interactions with the ABTS cation radical (2003) (197)
- Melatonin alleviates acute lung injury through inhibiting the NLRP3 inflammasome (2016) (196)
- Melatonin induces nitric oxide and the potential mechanisms relate to innate immunity against bacterial pathogen infection in Arabidopsis (2015) (190)
- On the significance of an alternate pathway of melatonin synthesis via 5‐methoxytryptamine: comparisons across species (2016) (186)
- Ischemia/reperfusion‐induced arrhythmias in the isolated rat heart: Prevention by melatonin (1998) (186)
- Novel rhythms of N1‐acetyl‐N2‐formyl‐5‐methoxykynuramine and its precursor melatonin in water hyacinth: importance for phytoremediation (2007) (184)
- Augmentation of indices of oxidative damage in life-long melatonin-deficient rats (1999) (180)
- Neurotoxins: Free Radical Mechanisms and Melatonin Protection (2010) (180)
- Melatonin: A Versatile Protector against Oxidative DNA Damage (2018) (176)
- Peripheral Reproductive Organ Health and Melatonin: Ready for Prime Time (2013) (170)
- When Melatonin Gets on Your Nerves: Its Beneficial Actions in Experimental Models of Stroke (2005) (170)
- Melatonin‐induced neuroprotection after closed head injury is associated with increased brain antioxidants and attenuated late‐phase activation of NF‐κB and AP‐1 (2004) (168)
- Inhibition of neuronal nitric oxide synthase activity by N1‐acetyl‐5‐methoxykynuramine, a brain metabolite of melatonin (2006) (168)
- Phytoremediative Capacity of Plants Enriched with Melatonin (2007) (167)
- Melatonin induces browning of inguinal white adipose tissue in Zucker diabetic fatty rats (2013) (166)
- Melatonin induces class A1 heat‐shock factors (HSFA1s) and their possible involvement of thermotolerance in Arabidopsis (2015) (164)
- Melatonin reduces prostate cancer cell growth leading to neuroendocrine differentiation via a receptor and PKA independent mechanism (2005) (163)
- Protective effects of melatonin in experimental free radical‐related ocular diseases (2006) (157)
- Melatonin and the circadian system: contributions to successful female reproduction. (2014) (155)
- Mitochondria: the birth place, battle ground and the site of melatonin metabolism in cells (2019) (154)
- Melatonin and parkinson’s disease (2005) (153)
- Beneficial effect of resveratrol on bovine oocyte maturation and subsequent embryonic development after in vitro fertilization. (2014) (151)
- Melatonin, xanthurenic acid, resveratrol, EGCG, vitamin C and α‐lipoic acid differentially reduce oxidative DNA damage induced by Fenton reagents: a study of their individual and synergistic actions (2003) (150)
- Arabidopsis serotonin N‐acetyltransferase knockout mutant plants exhibit decreased melatonin and salicylic acid levels resulting in susceptibility to an avirulent pathogen (2015) (149)
- Role of melatonin in metabolic regulation (2009) (148)
- Melatonin and its metabolites as copper chelating agents and their role in inhibiting oxidative stress: a physicochemical analysis (2015) (147)
- DNA oxidatively damaged by chromium(III) and H(2)O(2) is protected by the antioxidants melatonin, N(1)-acetyl-N(2)-formyl-5-methoxykynuramine, resveratrol and uric acid. (2001) (145)
- INDOLE‐3‐ACETIC ACID INDUCIBLE 17 positively modulates natural leaf senescence through melatonin‐mediated pathway in Arabidopsis (2015) (144)
- Fundamental Issues Related to the Origin of Melatonin and Melatonin Isomers during Evolution: Relation to Their Biological Functions (2014) (143)
- Melatonin promotes the in vitro development of pronuclear embryos and increases the efficiency of blastocyst implantation in murine (2013) (142)
- Protection against oxidative protein damage induced by metal-catalyzed reaction or alkylperoxyl radicals: comparative effects of melatonin and other antioxidants. (2003) (141)
- Melatonin alleviates cadmium‐induced liver injury by inhibiting the TXNIP‐NLRP3 inflammasome (2017) (140)
- Delivery of pineal melatonin to the brain and SCN: role of canaliculi, cerebrospinal fluid, tanycytes and Virchow–Robin perivascular spaces (2014) (139)
- What constitutes a physiological concentration of melatonin? (2003) (134)
- Melatonin Reduces Oxidant Damage and Promotes Mitochondrial Respiration (2002) (133)
- Melatonin as a naturally occurring co‐substrate of quinone reductase‐2, the putative MT3 melatonin membrane receptor: hypothesis and significance (2007) (133)
- Melatonin as a Pharmacological Agent against Neuronal Loss in Experimental Models of Huntington's Disease, Alzheimer's Disease and Parkinsonism (1999) (131)
- Caloric restriction, resveratrol and melatonin: Role of SIRT1 and implications for aging and related-diseases (2015) (130)
- Melatonin induces the transcripts of CBF/DREB1s and their involvement in both abiotic and biotic stresses in Arabidopsis (2015) (130)
- Chloroplastic biosynthesis of melatonin and its involvement in protection of plants from salt stress (2017) (130)
- Melatonin and structurally-related, endogenous indoles act as potent electron donors and radical scavengers in vitro. (1996) (129)
- Melatonin uptake through glucose transporters: a new target for melatonin inhibition of cancer (2015) (129)
- Orally administered melatonin reduces oxidative stress and proinflammatory cytokines induced by amyloid‐β peptide in rat brain: a comparative, in vivo study versus vitamin C and E (2003) (129)
- Increased levels of oxidatively damaged DNA induced by chromium(III) and H2O2: protection by melatonin and related molecules (2000) (128)
- A label‐free differential proteomics analysis reveals the effect of melatonin on promoting fruit ripening and anthocyanin accumulation upon postharvest in tomato (2016) (127)
- Melatonin protects hippocampal neurons in vivo against kainic acid‐induced damage in mice (1998) (126)
- Melatonin and sirtuins: A “not‐so unexpected” relationship (2017) (124)
- Chromium(III)-induced 8-hydroxydeoxyguanosine in DNA and its reduction by antioxidants: comparative effects of melatonin, ascorbate, and vitamin E. (2000) (124)
- Pharmacological utility of melatonin in the treatment of septic shock: experimental and clinical evidence (2006) (123)
- Role of melatonin in the regulation of autophagy and mitophagy: A review (2012) (122)
- Beneficial effects of melatonin in cardiovascular disease (2010) (122)
- Beneficial effects of melatonin on bovine oocytes maturation: a mechanistic approach (2014) (122)
- Pineal Calcification, Melatonin Production, Aging, Associated Health Consequences and Rejuvenation of the Pineal Gland (2018) (119)
- Oxidative Damage to Catalase Induced by Peroxyl Radicals: Functional Protection by Melatonin and Other Antioxidants (2003) (117)
- Comparative physiological and proteomic analyses reveal the actions of melatonin in the reduction of oxidative stress in Bermuda grass (Cynodon dactylon (L). Pers.) (2015) (117)
- Protective Effects of Melatonin and Mitochondria-targeted Antioxidants Against Oxidative Stress: A Review. (2015) (116)
- Melatonin reduces lipid peroxidation and membrane viscosity (2014) (115)
- Melatonin enhances cold tolerance in drought‐primed wild‐type and abscisic acid‐deficient mutant barley (2016) (114)
- Melatonin and tryptophan derivatives as free radical scavengers and antioxidants. (1999) (114)
- Melatonin combats molecular terrorism at the mitochondrial level (2008) (113)
- Melatonin: detoxification of oxygen and nitrogen-based toxic reactants. (2003) (113)
- Chronic melatonin treatment prevents age-dependent cardiac mitochondrial dysfunction in senescence-accelerated mice (2007) (107)
- Melatonin in edible plants (phytomelatonin): Identification, concentrations, bioavailability and proposed functions. (2007) (105)
- Melatonin promotes embryonic development and reduces reactive oxygen species in vitrified mouse 2‐cell embryos (2012) (105)
- Melatonin reduces oxidative neurotoxicity due to quinolinic acid: in vitro and in vivo findings (2000) (103)
- Diabetes and Alzheimer Disease, Two Overlapping Pathologies with the Same Background: Oxidative Stress (2015) (102)
- Melatonin defeats neurally-derived free radicals and reduces the associated neuromorphological and neurobehavioral damage. (2007) (101)
- Purslane: a plant source of omega‐3 fatty acids and melatonin (2005) (100)
- Melatonin alleviates low PS I‐limited carbon assimilation under elevated CO2 and enhances the cold tolerance of offspring in chlorophyll b‐deficient mutant wheat (2018) (97)
- Significance of High Levels of Endogenous Melatonin in Mammalian Cerebrospinal Fluid and in the Central Nervous System (2010) (96)
- Natural Variation in Banana Varieties Highlights the Role of Melatonin in Postharvest Ripening and Quality. (2017) (94)
- Melatonin Relieves the Neural Oxidative Burden that Contributes to Dementias (2004) (91)
- Identification of genes for melatonin synthetic enzymes in ‘Red Fuji’ apple (Malus domestica Borkh.cv.Red) and their expression and melatonin production during fruit development (2013) (80)
- Comparative metabolomic analysis highlights the involvement of sugars and glycerol in melatonin-mediated innate immunity against bacterial pathogen in Arabidopsis (2015) (80)
- Scientific Basis for the Potential Use of Melatonin in Bone Diseases: Osteoporosis and Adolescent Idiopathic Scoliosis (2010) (79)
- Essential actions of melatonin in protecting the ovary from oxidative damage. (2014) (79)
- Inhibitory effect of melatonin on products of lipid peroxidation resulting from chronic ethanol administration. (1999) (78)
- Role of melatonin in the epigenetic regulation of breast cancer (2009) (77)
- Clinical relevance of melatonin in ovarian and placental physiology: a review (2014) (74)
- The photoperiod, circadian regulation and chronodisruption: the requisite interplay between the suprachiasmatic nuclei and the pineal and gut melatonin. (2011) (74)
- Antioxidant activity of melatonin in Chinese hamster ovarian cells: changes in cellular proliferation and differentiation. (2003) (73)
- Melatonin identified in meats and other food stuffs: potentially nutritional impact (2014) (73)
- An evolutionary view of melatonin synthesis and metabolism related to its biological functions in plants. (2020) (73)
- Melatonin in the oral cavity: physiological and pathological implications. (2015) (72)
- Melatonin as a pharmacological agent against oxidative damage to lipids and DNA. (1998) (72)
- Melatonin inhibits fatty acid-induced triglyceride accumulation in ROS17/2.8 cells: implications for osteoblast differentiation and osteoporosis. (2007) (71)
- Role of melatonin on production and preservation of gametes and embryos: a brief review. (2014) (70)
- Beneficial actions of melatonin in the management of viral infections: a new use for this “molecular handyman”? (2012) (70)
- Melatonin Mitigates Mitochondrial Meltdown: Interactions with SIRT3 (2018) (70)
- Cyclic-3-hydroxymelatonin (C3HOM), a potent antioxidant, scavenges free radicals and suppresses oxidative reactions. (2014) (69)
- Melatonin Reduces Lipid Peroxidation and Tissue Edema in Cerulein-Induced Acute Pancreatitis in Rats (1999) (69)
- Ebola virus disease: potential use of melatonin as a treatment (2014) (69)
- Melatonin, Longevity and Health in the Aged: An Assessment (2002) (67)
- Accumulation of Exogenous Amyloid-Beta Peptide in Hippocampal Mitochondria Causes Their Dysfunction: A Protective Role for Melatonin (2012) (67)
- The protective role of endogenous melatonin in carrageenan‐induced pleurisy in the rat (1999) (67)
- Protective effects of melatonin against oxidation of guanine bases in DNA and decreased microsomal membrane fluidity in rat liver induced by whole body ionizing radiation (2000) (66)
- Cyclic 3-Hydroxymelatonin: A Melatonin Metabolite Generated as a Result of Hydroxyl Radical Scavenging (1999) (66)
- Melatonin enhances the occurrence of autophagy induced by oxidative stress in Arabidopsis seedlings (2015) (65)
- Melatonin Ameliorates Neurologic Damage and Neurophysiologic Deficits in Experimental Models of Stroke (2003) (65)
- Melatonin Improves Waterlogging Tolerance of Malus baccata (Linn.) Borkh. Seedlings by Maintaining Aerobic Respiration, Photosynthesis and ROS Migration (2017) (65)
- Predominance of 2‐hydroxymelatonin over melatonin in plants (2015) (65)
- Melatonin Improves the Quality of In Vitro Produced (IVP) Bovine Embryos: Implications for Blastocyst Development, Cryotolerance, and Modifications of Relevant Gene Expression (2014) (63)
- Melatonin's role as a co‐adjuvant treatment in colonic diseases: A review (2017) (61)
- Melatonin and its derivatives cyclic 3‐hydroxymelatonin, N1‐acetyl‐N2‐formyl‐5‐methoxykynuramine and 6‐methoxymelatonin reduce oxidative DNA damage induced by Fenton reagents (2003) (61)
- In vivo and in vitro effects of the pineal gland and melatonin on [Ca2++ Mg2+]‐dependent ATPase in cardiac sarcolemma (1993) (60)
- Functional aspects of redox control during neuroinflammation. (2010) (60)
- Emergence of naturally occurring melatonin isomers and their proposed nomenclature (2012) (59)
- Melatonin therapy in fibromyalgia (2007) (59)
- Critical role of glutathione in melatonin enhancement of tumor necrosis factor and ionizing radiation‐induced apoptosis in prostate cancer cells in vitro (2008) (58)
- Interactions between melatonin and nicotinamide nucleotide: NADH preservation in cells and in cell‐free systems by melatonin (2005) (58)
- Reactive Oxygen Species and the Hypomotility of the Gall Bladder as Targets for the Treatment of Gallstones with Melatonin: A Review (2008) (57)
- Cyclic 3-hydroxymelatonin, a key metabolite enhancing the peroxyl radical scavenging activity of melatonin (2014) (56)
- Role of melatonin in reduction of lipid peroxidation and peroxynitrite formation in non-septic shock induced by zymosan. (1999) (55)
- Urinary metabolites and antioxidant products of exogenous melatonin in the mouse (2006) (55)
- Cardiac hypertrophy and remodelling: pathophysiological consequences and protective effects of melatonin (2010) (54)
- Antioxidant strategies in protection against neurodegenerative disorders (2003) (54)
- CSF generation by pineal gland results in a robust melatonin circadian rhythm in the third ventricle as an unique light/dark signal. (2016) (54)
- Melatonin reduces phenylhydrazine-induced oxidative damage to cellular membranes: evidence for the involvement of iron. (2000) (54)
- Melatonin in relation to the "strong" and "weak" versions of the free radical theory of aging. (2008) (54)
- Inhibitory effects of melatonin on ferric nitrilotriacetate-induced lipid peroxidation and oxidative DNA damage in the rat kidney. (1999) (53)
- Kinetics of the neuroinflammation-oxidative stress correlation in rat brain following the injection of fibrillar amyloid-β onto the hippocampus in vivo (2004) (53)
- Inconsistent suppression of nocturnal pineal melatonin synthesis and serum melatonin levels in rats exposed to pulsed DC magnetic fields. (1998) (53)
- Melatonin reduces mortality and oxidatively mediated hepatic and renal damage due to diquat treatment (2007) (52)
- Melatonin reduces the oxidation of nuclear DNA and membrane lipids induced by the carcinogen δ‐aminolevulinic acid (2000) (51)
- Melatonin as pharmacologic support in burn patients: A proposed solution to thermal injury–related lymphocytopenia and oxidative damage (2007) (51)
- Circadian mechanisms in the regulation of melatonin synthesis: disruption with light at night and the pathophysiological consequences - (2011) (51)
- Physiological ischemia/reperfusion phenomena and their relation to endogenous melatonin production (2005) (50)
- Melatonin uptake in prostate cancer cells: intracellular transport versus simple passive diffusion (2008) (50)
- Role of CSF in the transport of melatonin (2002) (50)
- N-Acetylserotonin and 6-Hydroxymelatonin against Oxidative Stress: Implications for the Overall Protection Exerted by Melatonin. (2015) (49)
- Effects of Melatonin on the Proliferation and Apoptosis of Sheep Granulosa Cells under Thermal Stress (2014) (48)
- Melatonin as adjuvant treatment for coronavirus disease 2019 pneumonia patients requiring hospitalization (MAC-19 PRO): a case series (2020) (47)
- Melatonin reduces rat hepatic macromolecular damage due to oxidative stress caused by delta-aminolevulinic acid. (2000) (46)
- Neurally-mediated and neurally-independent beneficial actions of melatonin in the gastrointestinal tract. (2003) (45)
- Drug-mediated ototoxicity and tinnitus: alleviation with melatonin. (2011) (45)
- Potential utility of melatonin in deadly infectious diseases related to the overreaction of innate immune response and destructive inflammation: focus on COVID-19 (2020) (45)
- Phenolic Melatonin-Related Compounds: Their Role as Chemical Protectors against Oxidative Stress (2016) (44)
- N-acetylserotonin suppresses hepatic microsomal membrane rigidity associated with lipid peroxidation. (2001) (44)
- Suppression of oxygen toxicity by melatonin. (1998) (44)
- Glucose: A vital toxin and potential utility of melatonin in protecting against the diabetic state (2012) (44)
- Combination of melatonin and a peroxisome proliferator‐activated receptor‐γ agonist induces apoptosis in a breast cancer cell line (2009) (43)
- Renal toxicity of the carcinogen δ-aminolevulinic acid: antioxidant effects of melatonin (2000) (43)
- Melatonin Attenuates Estradiol-Induced Oxidative Damage to DNA: Relevance for Cancer Prevention (2001) (42)
- Effects of melatonin and its analogues on neural stem cells (2016) (41)
- A Walnut-Enriched Diet Reduces the Growth of LNCaP Human Prostate Cancer Xenografts in Nude Mice (2013) (41)
- Selective inhibition of Ebola entry with selective estrogen receptor modulators by disrupting the endolysosomal calcium (2017) (40)
- Inhibitory effect of melatonin on diquat‐induced lipid peroxidation in vivo as assessed by the measurement of F2‐isoprostanes (2006) (39)
- Targeting Host Defense System and Rescuing Compromised Mitochondria to Increase Tolerance against Pathogens by Melatonin May Impact Outcome of Deadly Virus Infection Pertinent to COVID-19 (2020) (39)
- Impaired mitochondrial complex III and melatonin responsive reactive oxygen species generation in kidney mitochondria of db/db mice (2011) (39)
- Abnormal circadian rhythm of melatonin in Smith–Magenis syndrome patients with RAI1 point mutations (2011) (38)
- Melatonin prevents the suppression of cardiac Ca(2+)-stimulated ATPase activity induced by alloxan. (1994) (37)
- Melatonin as a Potential Agent in the Treatment of Sarcopenia (2016) (36)
- Red-light-induced suppression of melatonin synthesis is mediated by N-methyl-D-aspartate receptor activation in retinally normal and retinally degenerate rats. (1995) (35)
- Melatonin's role in preventing toxin-related and sepsis-mediated hepatic damage: A review. (2016) (34)
- Inhibitory effect of melatonin on homocysteine-induced lipid peroxidation in rat brain homogenates. (2002) (34)
- Changes in lipid peroxidation during pregnancy and after delivery in rats: effect of pinealectomy. (2000) (33)
- Acute and delayed sulfur mustard toxicity; novel mechanisms and future studies (2008) (32)
- Melatonin in the biliary tract and liver: health implications. (2014) (31)
- Melatonin Protects the Heart against both Ischemia/Reperfusion Injury and Chemotherapeutic Drugs (2004) (31)
- Alterations in Lipid Levels of Mitochondrial Membranes Induced by Amyloid-β: A Protective Role of Melatonin (2012) (30)
- Potential benefits of melatonin in organ transplantation: a review. (2016) (29)
- MELATONIN: POTENTIAL UTILITY FOR IMPROVING PUBLIC HEALTH (2006) (29)
- Reduction in pineal N-acetyltransferase activity and pineal and serum melatonin levels in rats after their exposure to red light at night (1993) (28)
- A Computer-Assisted Systematic Search for Melatonin Derivatives with High Potential as Antioxidants (2018) (28)
- Hyperglycemia-related pathophysiologic mechanisms and potential beneficial actions of melatonin. (2008) (26)
- Antioxidative Capacity of Melatonin (2001) (26)
- Light pollution, melatonin suppression and cancer growth (2006) (26)
- Melatonin suppresses autoxidation and hydrogen peroxide-induced lipid peroxidation in monkey brain homogenate. (2000) (25)
- Unusual responses of nocturnal pineal melatonin synthesis and secretion to swimming: Attempts to define mechanisms (1993) (25)
- Autoxidation and toxicant-induced oxidation of lipid and DNA in monkey liver: reduction of molecular damage by melatonin. (2001) (24)
- A Genome-Wide Expression Profile of Salt-Responsive Genes in the Apple Rootstock Malus zumi (2013) (24)
- 2-Nitropropane-induced lipid peroxidation: antitoxic effects of melatonin. (1998) (24)
- A novel enzyme‐dependent melatonin metabolite in humans (2012) (24)
- 5‐methoxytryptophol preserves hepatic microsomal membrane fluidity during oxidative stress (2000) (23)
- Historical Perspective and Evaluation of the Mechanisms by which Melatonin Mediates Seasonal Reproduction in Mammals (2018) (23)
- Effects of melatonin on superovulation and transgenic embryo transplantation in small-tailed han sheep (Ovis aries). (2013) (22)
- The key role of the sequential proton loss electron transfer mechanism on the free radical scavenging activity of some melatonin-related compounds (2016) (22)
- Melatonin antagonizes interleukin‐18‐mediated inhibition on neural stem cell proliferation and differentiation (2017) (21)
- Melatonin prevents δ-aminolevulinic acid-induced oxidative DNA damage in the presence of Fe2+ (2001) (21)
- Melatonin and plants (2015) (20)
- Melatonin, vitamin E, and estrogen reduce damage induced by kainic acid in the hippocampus: potassium‐stimulated GABA release (2001) (19)
- Melatonin Reduces 3H-Nitrendipine Binding in the Heart (1994) (19)
- Renal toxicity of the carcinogen delta-aminolevulinic acid: antioxidant effects of melatonin. (2000) (19)
- When the Circadian Clock Becomes a Ticking Time Bomb (2012) (18)
- Melatonin protection from chronic, low-level ionizing radiation. (2012) (18)
- Melatonin and cardiac pathophysiology (2009) (17)
- Epigenetic mechanisms in human physiology and diseases (2011) (16)
- Analysis of N1‐acetyl‐N2‐formyl‐5‐methoxykynuramine/N1‐acetyl‐5‐methoxy‐kynuramine formation from melatonin in mice (2010) (16)
- The disaster in Japan: utility of melatonin in providing protection against ionizing radiation (2011) (16)
- Melatonin role preventing steatohepatitis and improving liver transplantation results (2016) (16)
- Radical-trapping and preventive antioxidant effects of 2-hydroxymelatonin and 4-hydroxymelatonin: Contributions to the melatonin protection against oxidative stress. (2017) (15)
- Protection by melatonin in respiratory diseases: valuable information for the treatment of COVID-19 (2020) (13)
- Melatonin; from pineal gland to healthy foods - (2011) (13)
- Radical and Reactive Intermediate-Scavenging Properties of Melatonin in Pure Chemical Systems (2001) (13)
- Role of SIRT3/SOD2 signaling in mediating the antioxidant actions of melatonin in mitochondria (2017) (13)
- Melatonin as a mitochondria-targeted antioxidant: one of evolution’s best ideas (2017) (12)
- Melatonin and related compounds: Chemical insights into their protective effects against oxidative stress (2017) (12)
- Melatonin and Brain (2010) (12)
- Melatonin: Reducing intracellular hostilities (2004) (12)
- Enterochromaffin cells as the source of melatonin: key findings and functional relevance in mammals (2019) (11)
- Melatonin Promotes Superovulation in Sika Deer (Cervus nippon) (2014) (11)
- Melatonin (2002) (11)
- Mechanisms and clinical evidence to support melatonin's use in severe COVID-19 patients to lower mortality (2022) (11)
- Melatonin in ventricular and subarachnoid cerebrospinal fluid: Its function in the neural glymphatic network and biological significance for neurocognitive health. (2022) (10)
- Melatonin; an Established Radioprotective Agent Against Japan’s Nuclear Disaster - (2011) (10)
- Melatonin Enhances Photo-Oxidation of 2′,7′-Dichlorodihydrofluorescein by an Antioxidant Reaction That Renders N1-Acetyl-N2-Formyl-5-Methoxykynuramine (AFMK) (2014) (10)
- Estimated doses of melatonin for treating deadly virus infections: focus on COVID-19 (2020) (10)
- Melatonin prevents delta-aminolevulinic acid-induced oxidative DNA damage in the presence of Fe2+. (2001) (10)
- Elevation of cyclic GMP levels in the rat pineal gland induced by nitric oxide (1994) (8)
- The Reserve/Maximum Capacity of Melatonin’s Synthetic Function for the Potential Dimorphism of Melatonin Production and Its Biological Significance in Mammals (2021) (7)
- Urgent search for safe and effective treatments of severe acute respiratory syndrome: is melatonin a promising candidate drug? (2003) (7)
- Antioxidant and Anti-Inflammatory Role of Melatonin in Alzheimer’s Neurodegeneration (2014) (7)
- Melatonin; an Established Radioprotective Agent Against Japan and #8217;s Nuclear Disaster (2011) (7)
- Melatonin and the pathophysiology of cellular membranes (2010) (7)
- The protective effects of melatonin on organisms against the environmental pollutants of heavy metal and non-mental toxins (2019) (6)
- Extrapineal melatonin: sources, regulation, and potential functions (2014) (6)
- Processes Underlying Chronodisruption and Their Proposed Association with Illness (2013) (5)
- The Oxidant/Antioxidant network (1999) (5)
- Melatonin reduces oxidative catastrophe in neurons and glia (2010) (5)
- Circadian Dysregulation and Melatonin Rhythm Suppression in the Context of Aging (2017) (5)
- [Ca2++Mg2+]-dependent ATPase activity in rat pineal gland (1993) (5)
- Melatonin Salvages Neural Tissue from Ischemia/Reperfusion Injury (2010) (5)
- Cholelithiasis, oxidative stress and melatonin. (2001) (5)
- Melatonin: Both a Messenger of Darkness and a Participant in the Cellular Actions of Non-Visible Solar Radiation of Near Infrared Light (2023) (4)
- Gastrointestinal tract and melatonin: Reducing pathophysiology (2010) (3)
- Aging: An evolutionary competition between host cells and mitochondria. (2019) (3)
- Antioxidant activity of pineal methoxyindoles on hepatocyte plasmatic membrane (2019) (3)
- Strategies to generate melatonin-enriched transgenic rice to respond to the adverse effects on rice production potentially caused by global warming (2021) (3)
- The protective effects of melatonin on organisms against the environmental pollutants of heavy metal and non-metal toxins (2020) (2)
- Melatonin use for SARS‐CoV‐2 infection: Time to diversify the treatment portfolio (2022) (2)
- Circadian rhythm abnormalities of melatonin and haploinsufficiency of COPS3 in Srnith-Magenis Syndrome (2000) (1)
- Melatonin reduces the mortality of severely-infected COVID-19 patients (2021) (1)
- [Ca(2+)+Mg2+]-dependent ATPase activity in rat pineal gland. (1993) (1)
- REVIEW - Genetic basis of neurodegeneration in familial Alzheimer's disease. Anna Kowalska . . 171 Synergistic effect of imipramine and amantadine in the forced swimming test in rats. (2004) (1)
- Brain washing and neural health: role of age, sleep, and the cerebrospinal fluid melatonin rhythm (2023) (1)
- cells: implications for osteoblast differentiation and osteoporosis Running title: Melatonin Inhibits TG Accumulation (2007) (1)
- A perspective on the proposed association of melatonin and aging (1998) (1)
- The physiology and pathology of skeletal and cardiac muscle: Beneficial actions of melatonin (2017) (1)
- Delivery of pineal melatonin to the brain and SCN: role of canaliculi, cerebrospinal fluid, tanycytes and Virchow–Robin perivascular spaces (2014) (0)
- Reduction of oxidative stress by melatonin: Physiology versus pharmacology (1998) (0)
- Feasibility of treatment of severe acute respiratory syndrome with maelatonin and its derivatives (2003) (0)
- Pineal Gland and Melatonin (2009) (0)
- Refresher corner Melatonin and cardiac pathophysiology (2009) (0)
- Genesis of the nucleus from bacterial sporulation: A simple hypothesis of eukaryotic origin. (2021) (0)
- A new promising role of melatonin in promoting tumor necrosis factor toxicity in cancer cells (2009) (0)
- Melatonin mitigates the damaging effects of ionizing radiation. (2008) (0)
- Contents Vol. 7, 2000 (2000) (0)
- Melatonin role preventing steatohepatitis and improving liver transplantation results (2016) (0)
- Role of CSF in the transport of melatonin (2002) (0)
- Aging-Related Ovarian Failure and Infertility: Melatonin to the Rescue (2023) (0)
- MelatoninReduces ProstateCancerCell Growth Leading toNeuroendocrineDifferentiationvia a Receptor andPKAIndependentMechanism (2005) (0)
- Placental melatonin: Beneficial effects for both the fetus and mother (2013) (0)
- Melatonin as a free radical scavenger: implications for experimental medicine (2006) (0)
- Subject Index Vol. 7, 2000 (2000) (0)
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