Duojia Pan
#104,556
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Chinese-American developmental biologist
Duojia Pan's AcademicInfluence.com Rankings
Duojia Panbiology Degrees
Biology
#6070
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#8703
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Developmental Biology
#192
World Rank
#200
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Biology
Duojia Pan's Degrees
- PhD Developmental Biology University of California, Berkeley
- Bachelors Biology Peking University
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Why Is Duojia Pan Influential?
(Suggest an Edit or Addition)According to Wikipedia, Duojia Pan is a Chinese-American developmental biologist at the University of Texas Southwestern Medical Center, where he is Fouad A. and Val Imm Bashour Distinguished Professor of Physiology, chairman of the department of physiology, and investigator of the Howard Hughes Medical Institute . His research is focused on molecular mechanisms of growth control and tissue homeostasis and their implications in human disease.
Duojia Pan's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Elucidation of a Universal Size-Control Mechanism in Drosophila and Mammals (2007) (2119)
- The hippo signaling pathway in development and cancer. (2010) (2023)
- The Hippo Signaling Pathway Coordinately Regulates Cell Proliferation and Apoptosis by Inactivating Yorkie, the Drosophila Homolog of YAP (2005) (1631)
- Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP. (2012) (1096)
- hippo Encodes a Ste-20 Family Protein Kinase that Restricts Cell Proliferation and Promotes Apoptosis in Conjunction with salvador and warts (2003) (1036)
- Rheb is a direct target of the tuberous sclerosis tumour suppressor proteins (2003) (926)
- Nuclear CDKs Drive Smad Transcriptional Activation and Turnover in BMP and TGF-β Pathways (2009) (688)
- Tsc tumour suppressor proteins antagonize amino-acid–TOR signalling (2002) (685)
- The Merlin/NF2 tumor suppressor functions through the YAP oncoprotein to regulate tissue homeostasis in mammals. (2010) (674)
- Hippo signaling in organ size control. (2007) (625)
- The TEAD/TEF family protein Scalloped mediates transcriptional output of the Hippo growth-regulatory pathway. (2008) (612)
- Kuzbanian Controls Proteolytic Processing of Notch and Mediates Lateral Inhibition during Drosophila and Vertebrate Neurogenesis (1997) (562)
- Expression of Yes-associated protein in common solid tumors. (2008) (552)
- Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded. (2010) (478)
- The Hippo signaling pathway restricts the oncogenic potential of an intestinal regeneration program. (2010) (457)
- Spatial Organization of Hippo Signaling at the Plasma Membrane Mediated by the Tumor Suppressor Merlin/NF2 (2013) (419)
- The Hippo Signaling Pathway in Development and Disease. (2019) (405)
- KUZ, a Conserved Metalloprotease-Disintegrin Protein with Two Roles in Drosophila Neurogenesis (1996) (366)
- The apical transmembrane protein Crumbs functions as a tumor suppressor that regulates Hippo signaling by binding to Expanded (2010) (331)
- Protein kinase A activates the Hippo pathway to modulate cell proliferation and differentiation. (2013) (278)
- A YAP/TAZ-induced feedback mechanism regulates Hippo pathway homeostasis (2015) (257)
- cAMP-dependent protein kinase and hedgehog act antagonistically in regulating decapentaplegic transcription in drosophila imaginal discs (1995) (239)
- The Hippo effector Yorkie controls normal tissue growth by antagonizing scalloped-mediated default repression. (2013) (228)
- The cell surface metalloprotease/disintegrin Kuzbanian is required for axonal extension in Drosophila. (1996) (193)
- Toll Receptor-Mediated Hippo Signaling Controls Innate Immunity in Drosophila (2016) (191)
- A temporal requirement for Hippo signaling in mammary gland differentiation, growth, and tumorigenesis (2014) (188)
- Yes-associated Protein Isoform 1 (Yap1) Promotes Cardiomyocyte Survival and Growth to Protect against Myocardial Ischemic Injury* (2012) (188)
- Identification of Happyhour/MAP4K as Alternative Hpo/Mst-like Kinases in the Hippo Kinase Cascade. (2015) (170)
- YAP Nuclear Localization in the Absence of Cell-Cell Contact Is Mediated by a Filamentous Actin-dependent, Myosin II- and Phospho-YAP-independent Pathway during Extracellular Matrix Mechanosensing* (2016) (162)
- Tuberous sclerosis complex: from Drosophila to human disease. (2004) (161)
- β-Catenin destruction complex-independent regulation of Hippo–YAP signaling by APC in intestinal tumorigenesis (2015) (153)
- Autopalmitoylation of TEAD Proteins Regulates Transcriptional Output of Hippo Pathway (2016) (151)
- Yes-Associated Protein Regulates the Hepatic Response After Bile Duct Ligation (2012) (138)
- Structural and functional analysis of the YAP-binding domain of human TEAD2 (2010) (135)
- Structural basis for Mob1-dependent activation of the core Mst–Lats kinase cascade in Hippo signaling (2015) (133)
- A Functional Interaction between Hippo-YAP Signaling and FoxO1 Mediates the Oxidative Stress Response (2014) (127)
- YAP Is Essential for Treg-Mediated Suppression of Antitumor Immunity. (2018) (124)
- Homeostatic control of Hippo signaling activity revealed by an endogenous activating mutation in YAP (2015) (110)
- Premetazoan origin of the hippo signaling pathway. (2012) (107)
- Tsc2 is not a critical target of Akt during normal Drosophila development. (2004) (106)
- YAP Controls Endothelial Activation and Vascular Inflammation Through TRAF6 (2018) (105)
- Targeted expression of teashirt induces ectopic eyes in Drosophila. (1998) (99)
- Hippo Signaling Influences HNF4A and FOXA2 Enhancer Switching during Hepatocyte Differentiation (2014) (88)
- NF2 Activates Hippo Signaling and Promotes Ischemia/Reperfusion Injury in the Heart. (2016) (87)
- Spectrin regulates Hippo signaling by modulating cortical actomyosin activity (2015) (86)
- The Hippo Pathway in Human Upper Gastrointestinal Dysplasia and Carcinoma: A Novel Oncogenic Pathway (2007) (86)
- Drosophila Target of Rapamycin Kinase Functions as a Multimer (2006) (82)
- A RhoA–YAP–c-Myc signaling axis promotes the development of polycystic kidney disease (2018) (77)
- Merlin controls the repair capacity of Schwann cells after injury by regulating Hippo/YAP activity (2017) (76)
- Structural basis for autoactivation of human Mst2 kinase and its regulation by RASSF5. (2013) (76)
- Homeostatic Control of Hpo/MST Kinase Activity through Autophosphorylation-Dependent Recruitment of the STRIPAK PP2A Phosphatase Complex. (2017) (70)
- The Hippo effector Yorkie activates transcription by interacting with a histone methyltransferase complex through Ncoa6 (2014) (63)
- FADS3 is a Δ14Z sphingoid base desaturase that contributes to gender differences in the human plasma sphingolipidome (2019) (48)
- The Hippo signaling functions through the Notch signaling to regulate intrahepatic bile duct development in mammals. (2017) (40)
- Combined Treatment with Epigenetic, Differentiating, and Chemotherapeutic Agents Cooperatively Targets Tumor-Initiating Cells in Triple-Negative Breast Cancer. (2016) (38)
- YAP1 Oncogene is a Context-specific Driver for Pancreatic Ductal Adenocarcinoma (2018) (36)
- Expression of Yes-associated protein modulates Survivin expression in primary liver malignancies. (2012) (36)
- The Hippo Pathway in Liver Homeostasis and Pathophysiology. (2020) (35)
- Neurofibromatosis 2011: a report of the Children’s Tumor Foundation Annual Meeting (2011) (33)
- Yes-associated protein impacts adherens junction assembly through regulating actin cytoskeleton organization. (2016) (33)
- A functional interaction between Hippo-YAP signalling and FoxO 1 mediates the oxidative stress response (2014) (32)
- The use of Yes-associated protein expression in the diagnosis of persistent neonatal cholestatic liver disease. (2014) (27)
- Pancreas lineage allocation and specification are regulated by sphingosine-1-phosphate signalling (2017) (22)
- Spectrin couples cell shape, cortical tension, and Hippo signaling in retinal epithelial morphogenesis (2020) (19)
- Nerfin-1 represses transcriptional output of Hippo signaling in cell competition (2019) (18)
- The Phosphatase Subunit Tap42 Functions Independently of Target of Rapamycin to Regulate Cell Division and Survival in Drosophila (2005) (18)
- WWTR1(TAZ)-CAMTA1 reprograms endothelial cells to drive epithelioid hemangioendothelioma (2021) (18)
- Fat Flies Expanded the Hippo Pathway: A Matter of Size Control (2007) (17)
- Inhibitors of STAT3, β‐catenin, and IGF‐1R sensitize mouse PIK3CA‐mutant breast cancer to PI3K inhibitors (2017) (16)
- Hippo, Drosophila MST, is a novel modifier of motor neuron degeneration induced by knockdown of Caz, Drosophila FUS (2018) (13)
- Validating upstream regulators of Yorkie activity in Hippo signaling through scalloped-based genetic epistasis (2018) (13)
- YAPing Hippo Forecasts a New Target for Lung Cancer Prevention and Treatment. (2015) (11)
- YAP/TAZ drives cell proliferation and tumor growth via a polyamine-eIF5A hypusination-LSD1 axis (2022) (10)
- A YAP/TAZ-TEAD signalling module links endothelial nutrient acquisition to angiogenic growth (2022) (9)
- YAP 1 oncogene is a context-specific driver for pancreatic ductal adenocarcinoma (2019) (8)
- YAP induces an oncogenic transcriptional program through TET1-mediated epigenetic remodeling in liver growth and tumorigenesis (2022) (6)
- Characterization of a cdc14 null allele in Drosophila melanogaster (2018) (6)
- Genome editing in the unicellular holozoan Capsaspora owczarzaki suggests a premetazoan role for the Hippo pathway in multicellular morphogenesis (2022) (5)
- Genome editing of Capsaspora owczarzaki suggests an ancestral function of the Hippo signaling effector YAP/TAZ/Yorkie in cytoskeletal dynamics but not proliferation (2021) (4)
- A dRASSF-STRIPAK-Imd-JAK/STAT axis controls antiviral immune response in Drosophila. (2022) (3)
- The unfolding of the Hippo signaling pathway. (2022) (3)
- Multiphase coalescence mediates Hippo pathway activation (2022) (2)
- Animal Models of TSC: Insights from Drosophila (2010) (2)
- The Hippo effector Yorkie activates transcription by interacting with a histone 1 methyltransferase complex through Ncoa 6 2 3 4 (2)
- The phosphatase subunit Tap42 functions independently of TOR to regulate cell division and survival in Drosophila. (2005) (2)
- Faculty Opinions recommendation of Identification of ligands for DAF-12 that govern dauer formation and reproduction in C. elegans. (2006) (1)
- Identification of Happyhour / MAP 4 K as Alternative Hpo / Mst-like Kinases in the Hippo Kinase Cascade Graphical (2015) (1)
- The utility of Yes-associated protein (YAP) expression in the diagnosis of persistent neonatal cholestatic liver disease (2014) (1)
- Hippo Signaling Pathway in Liver Development and Regeneration (2011) (0)
- TSC1 and TSC2 tumor suppressors antagonize insulin signaling in cell growth (2001) (0)
- Faculty Opinions recommendation of Editing-defective tRNA synthetase causes protein misfolding and neurodegeneration. (2006) (0)
- Size matters (2004) (0)
- Author response: The Hippo effector Yorkie activates transcription by interacting with a histone methyltransferase complex through Ncoa6 (2014) (0)
- Faculty Opinions recommendation of Mosaic analysis with double markers reveals tumor cell of origin in glioma. (2011) (0)
- Faculty Opinions recommendation of Actin-binding and cell proliferation activities of angiomotin family members are regulated by Hippo pathway-mediated phosphorylation. (2014) (0)
- Abstract IA34: Hippo signaling in development and cancer (2013) (0)
- 3 Antagonists of the TOR pathway in animal cells (2004) (0)
- Author response: Spectrin regulates Hippo signaling by modulating cortical actomyosin activity (2015) (0)
- YAP–VGLL4 antagonism defines the major physiological function of the Hippo signaling effector YAP (2022) (0)
- Abstract 3726: Combinations of HDAC inhibitor, chemotherapeutic agent and retinoic acid induce growth arrest, differentiation and tumor regression in preclinical models of breast cancer. (2013) (0)
- Faculty Opinions recommendation of S6K1- and betaTRCP-mediated degradation of PDCD4 promotes protein translation and cell growth. (2006) (0)
- Expression of Yes-Associated Protein, YAP, in Common Solid Tumors (2009) (0)
- Author response: Nerfin-1 represses transcriptional output of Hippo signaling in cell competition (2019) (0)
- Correction: Characterization of a cdc14 null allele in Drosophila melanogaster (doi:10.1242/bio.035394) (2018) (0)
- Abstract B83: Loss of the Hippo pathway effector Yap disrupts pancreatic morphogenesis and exacerbates exocrine pancreatitis. (2012) (0)
- Faculty Opinions recommendation of Structural rules and complex regulatory circuitry constrain expression of a Notch- and EGFR-regulated eye enhancer. (2010) (0)
- Loss of the yes-associated protein disrupts pancreatic morphogenesis and exacerbates exocrine pancreatitis in mice (2013) (0)
- The YAP Transcriptional Co-Activator Is Not Required for Mouse Hematopoiesis, at Steady State or After 5FU Treatment. (2010) (0)
- Control of tissue growth: elucidation of the Hippo signaling pathway (2008) (0)
- Faculty Opinions recommendation of Probing transcription-specific outputs of β-catenin in vivo. (2012) (0)
- Faculty Opinions recommendation of Soluble factors mediate competitive and cooperative interactions between cells expressing different levels of Drosophila Myc. (2007) (0)
- Abstract 4231: Combination of epigenetic, differentiation and DNA damaging agents induce tumor cell death and stem cell depletion in breast cancer (2015) (0)
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