Edward A. Meighen

Edward A. Meighen's AcademicInfluence.com Rankings

Edward A. Meighen

Biology

#12847

World Rank

#16351

Historical Rank

Molecular Biology

#2117

World Rank

#2149

Historical Rank

biology Degrees

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Biology

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Edward A. Meighen's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Molecular biology of bacterial bioluminescence. (1991) (687)
Purification and structural identification of an autoinducer for the luminescence system of Vibrio harveyi. (1989) (387)
Bacterial bioluminescence: organization, regulation, and application of the lux genes (1993) (287)
Genetics of bacterial bioluminescence. (1994) (214)
Enzymes and Genes from the lux Operons of Bioluminescent Bacteria (1988) (188)
The natural furanone (5Z)-4-bromo-5-(bromomethylene)-3-butyl-2(5H)-furanone disrupts quorum sensing-regulated gene expression in Vibrio harveyi by decreasing the DNA-binding activity of the transcriptional regulator protein luxR. (2007) (176)
Physiological, biochemical and genetic control of bacterial bioluminescence. (1993) (164)
Purification and properties of bacterial luciferases. (1972) (157)
Nucleotide sequence, expression, and properties of luciferase coded by lux genes from a terrestrial bacterium. (1990) (144)
LitR, a new transcriptional activator in Vibrio fischeri, regulates luminescence and symbiotic light organ colonization (2002) (141)
The luxR gene product of Vibrio harveyi is a transcriptional activator of the lux promoter (1992) (103)
Cloning and Characterization of the Bile Salt Hydrolase Genes (bsh) from Bifidobacterium bifidum Strains (2004) (98)
Structure of a myristoyl-ACP-specific thioesterase from Vibrio harveyi. (1994) (97)
Binding site determination from kinetic data. Reduced flavin mononucleotide binding to bacterial luciferase. (1971) (89)
Bacterial luciferase. Chemistry of the reactive sulfhydryl. (1974) (79)
Chemical modification of bacterial luciferase with ethoxyformic anhydride: evidence for an essential histidyl residue. (1976) (78)
A new Vibrio fischeri lux gene precedes a bidirectional termination site for the lux operon (1990) (76)
Multiple repetitive elements and organization of the lux operons of luminescent terrestrial bacteria (1992) (75)
Crystal structure of the NADP+-dependent aldehyde dehydrogenase from Vibrio harveyi: structural implications for cofactor specificity and affinity. (2000) (74)
Autoregulation of luxR: the Vibrio harveyi lux‐operon activator functions as a repressor (1996) (65)
Delineation of the transcriptional boundaries of the lux operon of Vibrio harveyi demonstrates the presence of two new lux genes. (1990) (64)
BIOTECHNOLOGICAL APPLICATIONS OF BACTERIAL BIOLUMINESCENCE (lux) GENES (1995) (63)
Conversion of aldehyde to acid in the bacterial bioluminescent reaction. (1973) (63)
Biosynthesis of poly-3-hydroxybutyrate in the luminescent bacterium, Vibrio harveyi, and regulation by the lux autoinducer, N-(3-hydroxybutanoyl)homoserine lactone. (1994) (61)
Hybridization of native and chemically modified enzymes. I. Development of a general method and its application to the study of the subunit structure of aldolase. (1970) (60)
Pheromone Biosynthesis: Enzymatic Studies in Lepidoptera (1987) (59)
A homoserine lactone autoinducer regulates virulence of an insect-pathogenic bacterium, Xenorhabdus nematophilus (Enterobacteriaceae) (1997) (59)
Biosynthesis and stereochemistry of the autoinducer controlling luminescence in Vibrio harveyi (1993) (58)
Functional identification of the fatty acid reductase components encoded in the luminescence operon of Vibrio fischeri (1985) (54)
The lux gene of the luminous bacterial symbiont, Photobacterium leiognathi, of the ponyfish (1991) (51)
Cloning and expression of the Photobacterium phosphoreum luminescence system demonstrates a unique lux gene organization. (1988) (50)
Complementation of subunits from different bacterial luciferases. Evidence for the role of the beta subunit in the bioluminescent mechanism. (1980) (49)
Proximal and distal sites bind LuxR independently and activate expression of the Vibrio harveyi lux operon (1994) (47)
Molecular biology of bacterial bioluminescence (1991) (47)
Functional differences of the nonidentical subunits of bacterial luciferase. Properties of hybrids of native and chemically modified bacterial luciferase. (1971) (47)
Purification of the acyl coenzyme A reductase component from a complex responsible for the reduction of fatty acids in bioluminescent bacteria. Properties and acyltransferase activity. (1983) (45)
Change of nucleotide specificity and enhancement of catalytic efficiency in single point mutants of Vibrio harveyi aldehyde dehydrogenase. (1999) (44)
Polycistronic mRNAs code for polypeptides of the Vibrio harveyi luminescence system (1985) (44)
Nucleotide sequence of the LuxC gene and the upstream DNA from the bioluminescent system of Vibrio harveyi. (1988) (44)
Riboflavin synthesis genes are linked with the lux operon of Photobacterium phosphoreum (1994) (42)
Fused bacterial luciferase subunits catalyze light emission in eukaryotes and prokaryotes. (1989) (42)
Hybridization of bacterial luciferase with a variant produced by chemical modification. (1971) (42)
The lux genes in Photobacterium leiognathi are closely linked with genes corresponding in sequence to riboflavin synthesis genes. (1992) (41)
Purification and properties of a NAD(P)H:flavin oxidoreductase from the luminous bacterium, Beneckea harveyi. (1977) (41)
LUX C, D AND E GENES OF THE Vibrio fischeri LUMINESCENCE OPERON CODE FOR THE REDUCTASE, TRANSFERASE, AND SYNTHETASE ENZYMES INVOLVED IN ALDEHYDE BIOSYNTHESIS (1989) (41)
Detection of pheromone biosynthetic and degradative enzymes in vitro. (1984) (39)
Purification and characterization of a poly(dA-dT) lux-specific DNA-binding protein from Vibrio harveyi and identification as LuxR. (1993) (37)
Random mutagenesis of bacterial luciferase: critical role of Glu175 in the control of luminescence decay. (2005) (37)
In vitro acylation of the transferrin receptor. (1984) (36)
Expression of bioluminescence by Escherichia coli containing recombinant Vibrio harveyi DNA (1987) (36)
Conversion of serine-114 to cysteine-114 and the role of the active site nucleophile in acyl transfer by myristoyl-ACP thioesterase from Vibrio harveyi. (1996) (35)
Aldehyde Pheromones in Lepidoptera: Evidence for an Acetate Ester Precursor in Choristoneura fumiferana (1984) (35)
Organization of the lux structural genes of Vibrio harveyi. Expression under the T7 bacteriophage promoter, mRNA analysis, and nucleotide sequence of the luxD gene. (1988) (35)
Resolution of the fatty acid reductase from Photobacterium phosphoreum into acyl protein synthetase and acyl-CoA reductase activities. Evidence for an enzyme complex. (1982) (34)
The LuxR regulator protein controls synthesis of polyhydroxybutyrate in Vibrio harveyi. (1998) (34)
A new lux gene in bioluminescent bacteria codes for a protein homologous to the bacterial luciferase subunits. (1988) (34)
Hybridization of native and chemically modified enzymes. 3. The catalytic subunits of aspartate transcarbamylase. (1970) (32)
Acyl-acyl carrier protein as a source of fatty acids for bacterial bioluminescence. (1985) (32)
Enzymatic reduction of fatty acids and acyl-CoAs to long chain aldehydes and alcohols (1985) (30)
Hybridization of native and chemically modified enzymes. II. Native and succinylated glyceraldehyde 3-phosphate dehydrogenase. (1970) (30)
Involvement of cysteine 289 in the catalytic activity of an NADP(+)-specific fatty aldehyde dehydrogenase from Vibrio harveyi. (1995) (30)
A lux-specific myristoyl transferase in luminescent bacteria related to eukaryotic serine esterases. (1991) (30)
Bacterial luciferase produced with rapid-screening baculovirus vectors is a sensitive reporter for infection of insect cells and larvae. (1992) (30)
Fatty acid acylation of proteins in bioluminescent bacteria (1983) (30)
Biosynthesis of the acetate ester precursor of the spruce budworm sex pheromone by an acetyl CoA: fatty alcohol acetyltransferase (1987) (28)
Evidence for a fatty acid reductase catalyzing the synthesis of aldehydes for the bacterial bioluminescent reaction. Resolution from luciferase and dependence on fatty acids. (1979) (28)
H-NS Protein Represses Transcription of the lux Systems of Vibrio fischeri and Other Luminous Bacteria Cloned into Escherichia coli (1997) (28)
Transcriptional regulation of lux genes transferred into Vibrio harveyi (1990) (27)
Induced polypeptide synthesis during the development of bacterial bioluminescence. (1976) (27)
Rate of pheromone release by individual spruce budworm moths (1982) (27)
In vivo and in vitro acylation of polypeptides in Vibrio harveyi: identification of proteins involved in aldehyde production for bioluminescence (1984) (26)
Autoinduction of light emission in different species of bioluminescent bacteria. (1999) (26)
Control of luminescence decay and flavin binding by the LuxA carboxyl-terminal regions in chimeric bacterial luciferases. (1999) (25)
Vibrio harveyi aldehyde dehydrogenase. Partial reversal of aldehyde oxidation and its possible role in the reduction of fatty acids for the bioluminescence reaction. (1984) (25)
Intersubunit transfer of fatty acyl groups during fatty acid reduction. (1986) (25)
Pheromone biosynthesis and role of functional groups in pheromone specificity (1986) (24)
Generation of fatty acids by an acyl esterase in the bioluminescent system of Photobacterium phosphoreum. (1984) (23)
Cloning, sequencing, and functional studies of the rpoS gene from Vibrio harveyi. (2002) (23)
Critical glutamic acid residues affecting the mechanism and nucleotide specificity of Vibrio harveyi aldehyde dehydrogenase. (1997) (23)
Biosynthesis of aliphatic aldehydes for the bacterial bioluminescent reaction: stimulation by ATP and NADPH. (1979) (23)
Identification of the acyl transfer site of fatty acyl-protein synthetase from bioluminescent bacteria. (1991) (23)
The lux genes of the luminous bacterial symbiont, Photobacterium leiognathi, of the ponyfish. Nucleotide sequence, difference in gene organization, and high expression in mutant Escherichia coli. (1991) (22)
Subunit interactions and the role of the luxA polypeptide in controlling thermal stability and catalytic properties in recombinant luciferase hybrids. (1993) (21)
Differential acylation in vitro with tetradecanoyl coenzyme A and tetradecanoic acid (+ATP) of three polypeptides shown to have induced synthesis in Photobacterium phosphoreum. (1984) (21)
Functional and structural properties of immobilized subunits of Escherichia coli alkaline phosphatase. (1980) (19)
Cloning and functional studies of a luxO regulator LuxT from Vibrio harveyi. (2000) (19)
An induced aliphatic aldehyde dehydrogenase from the bioluminescent bacterium, Beneckea harveyi. Purification and properties. (1978) (18)
Subunit structure of the fatty acid reductase complex from Photobacterium phosphoreum (1986) (17)
Co-induction of fatty acid reductase and luciferase during development of bacterial bioluminescence. (1980) (16)
ATP turnover by the fatty acid reductase complex of Photobacterium phosphoreum (1985) (16)
Fatty acyl-AMP as an intermediate in fatty acid reduction to aldehyde in luminescent bacteria. (1985) (16)
Adsorptive immobilization of bacterial luciferases on alkyl-substituted Sepharose 4B (2003) (15)
Changes in the kinetics and emission spectrum on mutation of the chromophore-binding platform in Vibrio harveyi luciferase. (2004) (15)
Purification and characterization of a luxO promoter binding protein LuxT from Vibrio harveyi. (2000) (15)
Bright stable luminescent yeast using bacterial luciferase as a sensor. (2003) (14)
Tryptophan 250 on the alpha subunit plays an important role in flavin and aldehyde binding to bacterial luciferase. Effects of W-->Y mutations on catalytic function. (1995) (14)
The turnover of bacterial luciferase is limited by a slow decomposition of the ternary enzyme-product complex of luciferase, FMN, and fatty acid. (1994) (14)
Construction of a fused LuxAB gene by site-directed mutagenesis. (1989) (13)
The gene convergent to luxG in Vibrio fischeri codes for a protein related in sequence to RibG and deoxycytidylate deaminase. (1993) (13)
Detection of poly(3-hydroxybutyrate) granules by electron microscopy of Vibrio harveyi stained with malachite green (1995) (13)
Subunit homologies in bacterial luciferases. (1970) (13)
In Vitro Synthesis of Subunits of Bacterial Luciferase in an Escherichia coli System (1983) (12)
The lux autoinducer-receptor interaction in Vibrio harveyi: binding parameters and structural requirements for the autoinducer. (1995) (12)
A miniaturized Ames mutagenicity assay employing bioluminescent strains of Salmonella typhimurium. (1995) (12)
Organization of the lux genes of photobacterium phosphoreum (1989) (12)
Induction of fatty aldehyde dehydrogenase activity during the development of bioluminescence in Beneckea harveyi. (1976) (12)
Structure and properties of luciferase from Photobacterium phosphoreum. (1991) (12)
Cysteine-286 as the site of acylation of the Lux-specific fatty acyl-CoA reductase. (1997) (11)
Involvement of conserved glycine residues, 229 and 234, of Vibrio harveyi aldehyde dehydrogenase in activity and nucleotide binding. (1997) (11)
Implications of the reactive thiol and the proximal non-proline cis-peptide bond in the Structure and function of Vibrio harveyi luciferase. (2002) (11)
Purification and characterization of a bioluminescence-related fatty acyl esterase from Vibrio harveyi. (1985) (10)
Differential regulation of enzyme activities involved in aldehyde metabolism in the luminescent bacterium Vibrio harveyi (1988) (10)
Sequential chemical modification of a histidyl and a cysteinyl residue in bacterial luciferase. (1977) (10)
Regulatory mutants of the Vibrio harveyi lux system (1989) (10)
Binding Site Determination from Kinetic Data (1971) (10)
Evidence for histidyl residues at the Zn2+ binding sites of monomeric and dimeric forms of alkaline phosphatase. (1981) (10)
Involvement of LuxR, a quorum sensing regulator in Vibrio harveyi, in the promotion of metabolic genes: argA, purM, lysE and rluA. (2006) (9)
CONTROLLED-RELEASE SEX PHEROMONE LURES FOR MONITORING SPRUCE BUDWORM POPULATIONS (1987) (9)
Flavine specificity of enzyme-substrate intermediates in the bacterial bioluminescent reaction. Structural requirements of the flavine side chain. (1973) (9)
[7] Cloning and expression of the genes from the bioluminescent system of marine bacteria (1986) (9)
Different sites for fatty acid activation and acyl transfer by the synthetase subunit of fatty acid reductase: acylation of a cysteinyl residue (1988) (8)
Development of a bioluminescence assay for aldehyde pheromones of insects (1982) (8)
A histidine residue in the catalytic mechanism distinguishes Vibrio harveyi aldehyde dehydrogenase from other members of the aldehyde dehydrogenase superfamily. (2000) (8)
Covalent reaction of cerulenin at the active site of acyl-CoA reductase of Photobacterium phosphoreum. (1989) (8)
Comparison of the lux systems in Vibrio harveyi and Vibrio fischeri (1989) (7)
Determination of the release rate of aldehyde pheromones from insect lures by cold trapping and direct bioluminescence analysis. (1983) (7)
Determination of the myofibrillar and connective tissue proteins in the bovine diaphragm (1988) (7)
Development of a bioluminescence assay for aldehyde pheromones of insects (1982) (7)
Development of a bioluminescence assay for aldehyde pheromones of insects (1982) (7)
Fatty acid reductase in bioluminescent bacteria. Resolution from aldehyde reductases and characterization of the aldehyde product. (1981) (7)
Tryptophan fluorescence of the lux-specific Vibrio harveyi acyl-ACP thioesterase and its tryptophan mutants: structural properties and ligand-induced conformational change. (1998) (6)
Hybrids of chemical derivatives of Escherichia coli alkaline phosphatase. (1975) (6)
Differences in nucleotide specificity and catalytic mechanism between Vibrio harveyi aldehyde dehydrogenase and other members of the aldehyde dehydrogenase superfamily. (2001) (5)
Fatty acid-enhanced binding of flavin mononucleotide to bacterial luciferase measured by steady-state fluorescence. (1992) (5)
Differential synthesis of the polypeptides of aldehyde dehydrogenase and NAD(P)H:flavin oxidoreductase in the bioluminescent bacterium Beneckea harveyi. (1978) (5)
A bioluminescent assay for aldehyde sex pheromones of insects (1981) (5)
[44] Immobilized subunits of alkaline phosphatase (1987) (4)
Expression, purification and crystallization of the Vibrio harveyi acyltransferase. (1992) (4)
[16] Bioluminescent analysis of insect pheromones (1986) (4)
Generation and properties of a luminescent insect pathogen Xenorhabdus nematophilus (Enterobacteriaceae). (1998) (3)
BACTERIAL BIOLUMINESCENCE: ACCESSORY ENZYMES1 (1981) (3)
Mutation of the nucleophilic elbow of the Lux-specific thioesterase from Vibrio harveyi. (2000) (3)
An essential histidine residue required for fatty acylation and acyl transfer by myristoyltransferase from luminescent bacteria. (1994) (3)
Structural and functional studies of a NADP(+)-specific aldehyde dehydrogenase from the luminescent marine bacterium Vibrio harveyi. (1997) (3)
Elucidation of the quaternary structure of reversibly immobilized alkaline phosphatase derivatives. (1979) (3)
Inhibition of Vibrio harveyi bioluminescence by cerulenin: in vivo evidence for covalent modification of the reductase enzyme involved in aldehyde synthesis (1989) (3)
Hyperactivity and interactions of a chimeric myristoryl-ACP thioesterase from the lux system of luminescent bacteria. (2000) (3)
Differences in oxidase and esterase activities involved in pheromone biosynthesis in two species ofChoristoneura (1990) (3)
Crystallization and preliminary X‐ray analysis of aldehyde dehydrogenase from Vibrio harveyi (1996) (3)
Mechanism of a long-chain fatty aldehyde dehydrogenase induced during the development of bioluminescence in Beneckea harveyi. (1983) (2)
Steady-state fluorescence and phosphorescence spectroscopic studies of bacterial luciferase tryptophan mutants (1994) (2)
[15] Bioluminescence-related acyltransferases from Photobacterium phosphoreum and Vibrio harveyi (1986) (2)
Expression and DNA Sequence of the Gene Coding for the lux-Specific Fatty Acyl-CoA Reductase from Photobacterium phosphoreum (2000) (2)
Vibrio harveyi RNA polymerase: purification and resolution from gyrase A. (1992) (2)
Determination of methylated basic amino acids, 5-hydroxylysine, and elastin crosslinks in proteins and tissues (1990) (2)
[18] Preparation of luciferases containing chemically modified subunits (1978) (2)
[14] Fatty acid reductase from Photobacterium phosphoreum (1986) (2)
CRYSTAL STRUCTURE OF THE NADP+ DEPENDENT ALDEHYDE DEHYDROGENASE FROM VIBRIO HARVEYI. (2000) (1)
Spectral Properties of Trp182, Trp194, and Trp250 on the α Subunit of Bacterial Luciferase (1999) (1)
BACTERIAL BIOLUMINESCENCE: APPLICATIONS TO ENTOMOLOGY (1981) (1)
Immobilized subunits of alkaline phosphatase. (1987) (1)
Subject Index, Vol. 34, 1992 (1992) (1)
Aldehyde in Luminescent Bacteria* (2001) (0)
MULTIPLE REGULATORY PROTEINS CONTROL INDUCTION OF LUMINESCENCE IN VIBRIO HARVEYI (2001) (0)
Inhibition ofVibrio harveyi Bioluminescence byCerulenin: InVivo Evidence forCovalent Modification oftheReductase Enzyme Involved inAldehyde Synthesis (1989) (0)
Inhibition of bacterial luminescence by cerulenin (1986) (0)
EFFECT OF SAM-RELATED STRUCTURAL AND REGULATORY PROTEINS ON LUMINESCENCE IN VIBRIO HARVEYI (2002) (0)
and Strains Bifidobacterium bifidum ) from bsh Salt Hydrolase Genes ( Cloning and Characterization of the Bile (2004) (0)
INVESTIGATIONS ON THE QUATERNARY STRUCTURE AND FUNCTION OF OLIGOMERIC PROTEINS BY HYBRIDIZATION WITH VARIANTS PRODUCED BY CHEMICAL MODIFICATION (1975) (0)
CHIMERIC BACTERIAL LUCIFERASES (2001) (0)
EVALUATION OF THE AFFINITY OF BACTERIAL LUCIFERASES FOR IMMOBILIZATION ON HYDROPHOBIC SUPPORTS (2002) (0)
Spectral properties of Trp182, Trp194, and Trp250 on the alpha subunit of bacterial luciferase. (1999) (0)
Enzyme Structure and Function (2004) (0)
Contents, Vol. 34, 1992 (1992) (0)
CRYSTAL STRUCTURE OF THE NADP+ DEPENDENT ALDEHYDE DEHYDROGENASE FROM VIBRIO HARVEYI. STRUCTURAL COMPARISON WITH NAD+ DEPENDENT ENZYMES. (1999) (0)
KINETICS AND FLUORESCENCE OF A BACTERIAL LUCIFERASE MUTANT WITH ONLY TWO TRYPTOPHANS (2001) (0)
BINDING OF FLAVIN AND ALDEHYDE TO THE ACTIVE SITE OF BACTERIAL LUCIFERASE (2002) (0)

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What Schools Are Affiliated With Edward A. Meighen?

Edward A. Meighen is affiliated with the following schools:

McGill University
Dalhousie University

Edward A. Meighen's Academic­Influence.com Rankings

Why Is Edward A. Meighen Influential?

Edward A. Meighen's Published Works

Published Works

What Schools Are Affiliated With Edward A. Meighen?

Edward A. Meighen's AcademicInfluence.com Rankings