Eldon A. Shaffer
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Eldon A. Shafferphilosophy Degrees
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Medical Philosophy
Eldon A. Shaffer's Degrees
- PhD Epidemiology University of California, Berkeley
- Doctorate Medicine University of California, San Francisco
Why Is Eldon A. Shaffer Influential?
(Suggest an Edit or Addition)Eldon A. Shaffer's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Epidemiology of Gallbladder Disease: Cholelithiasis and Cancer (2012) (885)
- Gallbladder cancer: epidemiology and outcome (2014) (755)
- Epidemiology of gallbladder stone disease (2006) (560)
- Role for protease activity in visceral pain in irritable bowel syndrome. (2007) (540)
- Epidemiology and risk factors for gallstone disease: Has the paradigm changed in the 21st century? (2005) (423)
- Gallstone disease: Epidemiology of gallbladder stone disease. (2006) (417)
- Biliary lipid secretion in cholesterol gallstone disease. The effect of cholecystectomy and obesity. (1977) (319)
- Abnormal gallbladder emptying in a subgroup of patients with gallstones. (1985) (243)
- Primary eosinophilic disorders of the gastrointestinal tract (2008) (192)
- Preoperative Oral Fluids: Is a Five‐hour Fast Justified Prior to Elective Surgery? (1986) (189)
- Gallbladder polyps: epidemiology, natural history and management. (2002) (181)
- Epidemiology of gallstones. (2010) (165)
- Defense system in the biliary tract against bacterial infection (1992) (157)
- Functional disorders of the biliary tract and pancreas (1999) (137)
- Quantitative cholescintigraphy: assessment of gallbladder filling and emptying and duodenogastric reflux. (1980) (136)
- Defective gallbladder contractility in the ground squirrel and prairie dog during the early stages of cholesterol gallstone formation. (1983) (130)
- Eosinophilic colitis: epidemiology, clinical features, and current management (2011) (124)
- HFE C282Y mutations are associated with advanced hepatic fibrosis in Caucasians with nonalcoholic steatohepatitis (2007) (119)
- Ascending infection of the biliary tract after surgical sphincterotomy and biliary stenting (1992) (116)
- Diagnosis of hepatobiliary disease by 99mTc-HIDA cholescintigraphy. (1978) (106)
- Bile composition at and after surgery in normal persons and patients with gallstones. Influence of cholecystectomy. (1972) (97)
- Gallbladder emptying in response to cholecystokinin. A cholescintigraphic study. (1979) (95)
- Collagenous colitis and microscopic colitis: the watery diarrhea-colitis syndrome. (1989) (91)
- Effect of oral liquids and ranitidine on gastric fluid volume and pH in children undergoing outpatient surgery. (1989) (88)
- Collagenous colitis: A disease of pericryptal fibroblast sheath? (1986) (87)
- The effect of ursodeoxycholic acid therapy on gallstone formation in the morbidly obese during rapid weight loss. (1993) (86)
- Intestinal absorption of bile salts: immature development in the neonate. (1979) (84)
- Bacterial biofilm, brown pigment stone and blockage of biliary stents (1993) (84)
- Gallbladder cancer: the basics. (2008) (83)
- Cholescintigraphic detection of functional obstruction of the sphincter of Oddi. Effect of papillotomy. (1986) (77)
- Chronic right upper quadrant pain without gallstones: does HIDA scan predict outcome after cholecystectomy? (1990) (74)
- Antibacterial activity of bile salts against common biliary pathogens (1993) (73)
- Review article: control of gall‐bladder motor function (2000) (70)
- The rising incidence of eosinophilic oesophagitis is associated with increasing biopsy rates: a population‐based study (2012) (69)
- Efficacy of bile acid therapy for gallstone dissolution: a meta‐analysis of randomized trials (1993) (67)
- Gallstone disease: pathogenesis and management. (1976) (66)
- Gallbladder sludge: What is its clinical significance? (2001) (65)
- Eosinophilic colitis: an update on pathophysiology and treatment. (2011) (64)
- POSTNATAL MATURATION OF HEPATIC BILE FORMATION IN THE RABBIT (1984) (59)
- Gallbladder function during gallstone dissolution. Effect of bile acid therapy in patients with gallstones. (1988) (57)
- Bacterial invasion of the biliary system by way of the portal‐venous system (1991) (57)
- Aspiration after percutaneous gastrostomy. Assessment by Tc-99m labeling of the enteral feed. (1987) (55)
- The association between celiac disease and eosinophilic esophagitis in children and adults (2013) (54)
- Pilot study of cyclosporin A in patients with symptomatic primary biliary cirrhosis. (1988) (54)
- The potential site of impaired gallbladder contractility in an animal model of cholesterol gallstone disease. (1996) (53)
- The histopathology of rectosigmoid biopsies from adults with bloody diarrhea due to verotoxin-producing Escherichia coli. (1987) (51)
- Involvement of L-arginine-nitric oxide pathways in neural relaxation of the sphincter of Oddi. (1993) (49)
- Eosinophilic esophagitis: a newly established cause of dysphagia. (2006) (49)
- Changes in gallbladder motility and gallstone formation following laparoscopic gastric banding for morbid obestity. (2003) (49)
- Bariatric surgery: a promising solution for nonalcoholic steatohepatitis in the very obese. (2006) (47)
- Gastric fluid volume pH, and emptying in elective inpatients Influences of narcoticatropine premedication oral fluid, and ranitidine (1988) (45)
- Effect of the prokinetic agent, erythromycin, in the richardson ground squirrel model of cholesterol gallstone disease (1998) (45)
- Cholestatic effects of cyclosporine in the rat. (1997) (44)
- The effect of a progestin on gallbladder function in young women. (1984) (43)
- Cisapride improves gallbladder contractility and bile lipid composition in an animal model of gallstone disease. (1993) (41)
- Nonvisualization of the gallbladder by 99mTc-HIDA cholescintigraphy as evidence of cholecystitis. (1978) (40)
- Acalculous biliary pain: new concepts for an old entity. (2003) (40)
- Effect of time of administration on cholesterol-lowering by psyllium: a randomized cross-over study in normocholesterolemic or slightly hypercholesterolemic subjects (2004) (39)
- Definition of a conjugation of dysfunction in Gilbert's syndrome: studies of the handling of bilirubin loads and of the pattern of bilirubin conjugates secreted in bile. (1978) (37)
- The Effect of Vagotomy on Gallbladder Function and Bile Composition in Man (1982) (37)
- Inhibitory effect of bile salts on gallbladder smooth muscle contractility in the guinea pig in vitro. (1997) (37)
- Bilirubin secretion and conjujation in the Crigler-Najjar syndrome type II. (1976) (36)
- The importance of triglyceride hydrolysis for the release of gastric inhibitory polypeptide (1981) (36)
- Effect of epidermal growth factor on growth and postnatal development of the rabbit liver. (1987) (35)
- CANADIAN ASSOCIATION OF GASTROENTEROLOGY CLINICAL PRACTICE GUIDELINE ON THE MANAGEMENT OF BILE ACID DIARRHEA. (2019) (33)
- Abnormalities in gallbladder function in cholesterol gallstone disease: bile and blood, mucosa and muscle--the list lengthens. (1992) (32)
- A physiological model to study gallbladder function in primates. (1974) (31)
- On the in vitro vasoactivity of bile acids (2000) (31)
- Hydrophobic bile salt inhibits bacterial adhesion on biliary stent material (1994) (31)
- The effects of liver transplantation and cyclosporine on bile formation and lipid composition: an experimental study in the rat. (1998) (30)
- Mechanism of bile salt vasoactivity: dependence on calcium channels in vascular smooth muscle (1994) (29)
- Regulation of fasting canine duodenal bile acid delivery by sphincter of Oddi and gallbladder. (1985) (28)
- Total parenteral nutrition-associated cholestasis: acute studies in infant and adult rabbits. (1985) (28)
- Intracellular pH influences the resting membrane potential of isolated rat hepatocytes. (1988) (28)
- Slow intestinal transit: A motor disorder contributing to cholesterol gallstone formation in the ground squirrel (1996) (26)
- The effects of prosthetic gallstones on gallbladder function and bile composition. (1986) (24)
- Eosinophilic colitis is a sporadic self‐limited disease of middle‐aged people: a population‐based study (2014) (22)
- Chronic biliary-type pain in the absence of gallstones: the value of cholecystokinin cholescintigraphy. (1992) (21)
- Ground squirrel hepatitis virus (GSHV) infection and hepatocellular carcinoma in the Canadian Richardson ground squirrel (Spermophilus richardsonii). (2008) (21)
- Biliary obstruction after cholecystectomy: diagnosis with quantitative cholescintigraphy. (1988) (20)
- Inhibition of gallbladder emptying decreases cholesterol saturation in bile in the richardson ground squirrel (1995) (19)
- Differential sensitivities of the sphincter of Oddi and gallbladder to cholecystokinin in the guinea pig: their role in transsphincteric bile flow. (1992) (19)
- Gastric fluid volume and pH in elective surgical patients: triple prophylaxis is not superior to ranitidine alone (1990) (19)
- The battle against the obesity epidemic: is bariatric surgery the perfect weapon? (2005) (19)
- Effects of liver transplantation on bile formation and biliary lipid secretion in the Sprague‐Dawley rat (1995) (18)
- The source of calcium for CCK-induced contraction of the guinea-pig gall bladder (1992) (17)
- Endoscopic removal of a foreign body perforating the duodenum. (1977) (17)
- Increased cholinergic contractions of jejunal smooth muscle caused by a high cholesterol diet are prevented by the 5-HT4 agonist – tegaserod (2006) (16)
- The natural history and significance of ultrasonographically defined polypoid lesions of the gallbladder in children. (2007) (15)
- Sodium-dependent taurocholate uptake by isolated rat hepatocytes occurs through an electrogenic mechanism. (1987) (15)
- The hot air and cold facts of dietary fibre. (2006) (15)
- Reduced Bile Output with Chronic Enteral and Parenteral Infusion of Amino Acids, Glucose, and Fat Emulsion in Rabbits (1985) (15)
- Protein-losing enteropathy in systemic lupus erythematosus associated with intestinal lymphangiectasia. (1990) (15)
- Mucosa-associated lymphoid tissue (MALT) lymphoma manifesting as multiple lymphomatosis polyposis of the gastrointestinal tract (1999) (14)
- Gallstone disease: Current therapeutic practice (2008) (14)
- Characterization of leukotriene-induced contraction of the guinea-pig gallbladder in vitro. (1993) (14)
- Sustained gallbladder stasis promotes cholesterol gallstone formation in the ground squirrel (1997) (14)
- Efficacy, duration, and absorption of a paediatric oral liquid preparation of ranitidine hydrochloride (1992) (14)
- Serum bile acids as related to bile acid secretion in liver disease (1978) (14)
- Cholestasis induced by oestrogen after liver transplantation. (1989) (14)
- Reticuloendothelial system Fc receptor‐mediated clearance of IgG‐tagged erythrocytes from the circulation of patients with idiopathic ulcerative colitis and chronic liver disease (1986) (14)
- The importance of triglyceride hydrolysis for the release of gastric inhibitory polypeptide. (1981) (14)
- Hyperprolactinemia in hepatic encephalopathy may result from impaired central dopaminergic neurotransmission. (1989) (13)
- Diagnosis of hepatobiliary disease by /sup 99m/Tc-HIDA cholescintigraphy (1978) (13)
- Benign recurrent intrahepatic cholestasis. Evidence for an intrinsic abnormality in hepatocyte secretion. (1987) (13)
- Cholestasis: the ABCs of cellular mechanisms for impaired bile secretion--transporters and genes. (2002) (13)
- Effects of bioactive agents on biliary motor function (2003) (12)
- The influence of bile salts on small intestinal motility in the guinea pig in vitro. (1992) (12)
- Postnatal development of hepatic bile formation in the rabbit (1985) (12)
- Oral contraceptives, smoking and nodular hyperplasia of the liver. (1978) (12)
- Absorption of triglycerides in the absence of lipase. (1990) (12)
- Benign recurrent intrahepatic cholestasis (1987) (11)
- A comparative study of the effects of insulin/glucagon infusions, parenteral amino acids and high dose corticosteroids on survival in a rabbit model of acute fulminant hepatitis (1986) (11)
- Anorectal condylomata acuminata: a missed part of the condyloma spectrum. (1978) (11)
- Altered migrating myoelectrical complex in an animal model of cholesterol gallstone disease: the effect of erythromycin (1998) (10)
- Effects of obesity on bile formation and biliary lipid secretion in the genetically obese JCR:LA‐corpulent rat (1994) (10)
- Child abuse with laxatives. (1982) (10)
- Eosinophilic esophagitis: an overlooked entity in chronic dysphagia (2006) (10)
- Mucosa-associated lymphoid tissue (MALT) lymphoma manifesting as multiple lymphomatosis polyposis of the gastrointestinal tract. (1999) (9)
- THE EFFECT OF CYCLOSPORINE AND LIVER AUTOTRANSPLANTATION ON BILE FLOW AND COMPOSITION IN DOGS1,2 (1993) (9)
- PREOPERATIVE ORAL FLUIDS: IS ???NPO AFTER MIDNIGHT??? JUSTIFIED? (1986) (9)
- Bile secretory function of the arterialized versus nonarterialized rat liver allograft. (1996) (9)
- Management of gastrointestinal hemorrhage. (1995) (8)
- Gallbladder pressure, compliance, and hysteresis during cyclic volume change. (1987) (8)
- In vitro effects of pancreatic polypeptide and motilin on contractility of human gallbladder (1983) (7)
- The use of a gonadotropin-releasing hormone analog and transdermal estrogen to preserve fertility in a woman with severe menorrhagia. (1989) (7)
- The Effect of Protein-Calorie Malnutrition on the Developing Liver (1988) (7)
- Nonalcoholic steatohepatitis: more than just being fat. (2002) (7)
- The Role of the Gallbladder in Gallstone Formation (1979) (7)
- Canadian Association of Gastroenterology Clinical Practice Guideline on the Management of Bile Acid Diarrhea (2019) (7)
- Bile salts determine leukotriene B4 synthesis in a human intestinal cell line (CaCo-2) (1994) (7)
- Cholescintigraphy in acalculous biliary pain: If abnormal, should cholecystectomy follow? (1992) (7)
- The basis for progesterone impairment of gallbladder contractility in male guinea pigs in vitro. (1998) (7)
- Consensus in Endoscopy (1996) (7)
- Endogenous endothelin increases gallbladder tone and leads to acute cholecystitis in the Australian possum (2004) (6)
- Epidemiology of Gallstones and Biliary Tract Cancers (2014) (6)
- Can MRCP replace ERCP in the diagnosis of congenital bile-duct cysts? (2006) (6)
- Insurance Rating of Patients with Inflammatory Bowel Disease: Report of a Conference on Morbidity and Mortality (1994) (5)
- A Novel Enteropathy with Partial Villous Atrophy, Microscopic Colitis, and Pemphigoid Change (1989) (5)
- Biliary Dyspepsia: Functional Gallbladder and Sphincter of Oddi Disorders (2013) (5)
- Spontaneous obesity and increased bile saturation in the ground squirrel. (1993) (4)
- Morphine and biliary pain revisited (2000) (4)
- Dyspepsia - Advances in Understanding and Management (2013) (4)
- Acalculous biliary pain: motility dysfunction and functional pain. (2001) (4)
- Gastroenterology fellowship training: approaches to curriculum assessment and evaluation. (2008) (3)
- Gallstones: current concepts of pathogenesis and medical dissolution. (1980) (3)
- Sulfobromophthalein and biliary lipid excretion (1981) (3)
- Pneumatosis Coli Associated with Pseudomembranous Colitis in a Patient following Colonic Surgery (2010) (3)
- Treatment of Ulcerative Colitis with 5-Aminosalicylic Acid (1993) (3)
- Modern Concepts in Gastroenterology Volume 2 (1989) (3)
- A simple and safe method of anesthetizing infant rabbits for abdominal surgery. (1983) (3)
- Direct determination of the contractility of the guinea pig gallbladder: a new in vivo model. (1985) (3)
- S1982 Rising Incidence of Eosinophilic Esophagitis in the Calgary Health Region: A Population-Based Study (2008) (3)
- The effect of cyclosporine A on bile secretion in dogs. (1990) (3)
- Effect of chlorpromazine (CPZ) on cholecystokinin-induced gallbladder contraction: the role of calcium. (1988) (2)
- Gallstone Disease: From Dyspepsia to Biliary Complications (2009) (2)
- Hepatocellular water and electrolyte secretion. (1988) (2)
- Measurement of gastric contents (1990) (2)
- The postendoscopy black eye. (1984) (2)
- Simmering innards: Does irritable bowel syndrome have an immunological basis? (2004) (2)
- Cholestasis and Total Parenteral Nutrition: In Vivo Studies on Dogs (1983) (2)
- The electrogenic effect of sodium taurocholate on rat hepatocyte couplets. (1987) (2)
- Flumazenil, a Benzodiazepine Receptor Anatagonist, in the Reversal of Conscious Sedation following Gastroscopy. A Placebo Controlled, Dose Finding Study (1991) (2)
- Solitary Lesions With Fibrosis and Increased IgG4+ Plasma Cells (2014) (2)
- The obesity epidemic: is bariatric surgery the antidote? (2005) (1)
- The effect of chlorpromazine on cholecystokinin induced gallbladder contraction. (1987) (1)
- Fc-receptor mediates clearance of immune complex-like material in Crohn's disease patients with elevated liver enzymes (1987) (1)
- Vagal effects on gallbladder emptying. (1986) (1)
- Determinants of biliary secretory pressure: the effects of two different bile acids. (1988) (1)
- Heart puncture--a simple and safe procedure for infusing fluids into and sampling from the cardiovascular system of infant animals. (1983) (1)
- The effect of bromosulphthalein (BSP) on biliary lipid secretion (1978) (1)
- Cholecystectomy also on rise in Alberta. (1996) (1)
- 661 IS TOTAL PARENTERAL NUTRITION (TPN) CHOLESTATIC? (1981) (1)
- HEPATOBILIARY IMAGING WITH 99mTc-LABELLED COMPOUNDS (1980) (1)
- Insurance rating of patients with IBD: a report of a conference on morbidity and mortality (1994) (0)
- Bile acid for gallstone dissolution (1993) (0)
- Leukotriene-induced contraction of isolated guinea pig gallbladder (GB) strips. (1992) (0)
- Issues raised by psyllium meta-analysis. (2001) (0)
- Intestinal absorption of bile development in the neonate salts: Immature (1979) (0)
- [Cholesteric biliary lithiasis: pathogeny and medical treatment]. (1974) (0)
- Gallstone Disease: Gallstone Disease: Current Therapeutic Practice Current Therapeutic Practice (2008) (0)
- A biliary pain: new concepts for an old entity (2003) (0)
- Effects of a Cholesterol-Enriched Diet on Intestinal Smooth Muscle Contraction : Inhibition of Muscarinic Receptors and their Disinhibition by the 5-HT 4 Agonist-Tegaserod (2005) (0)
- Diverticular Disease of the Colon : Review and Update (2003) (0)
- Eosinophilic Oesophagitis: Current Understanding and Future Directions (2016) (0)
- Butterworths International Medical Reviews (1982) (0)
- W1914 Clinical Features of Eosinophilic Colitis – A Report of 7 Consecutive Cases (2010) (0)
- The adherence of 99mTc-DISIDA to gallstones and gallbladder wall. (1984) (0)
- Bile acid for gallstone dissolution: A meta-analysis (1993) (0)
- Effects of tegaserod on bile composition and hepatic secretion in Richardson ground squirrels on an enriched cholesterol diet (2006) (0)
- Sphincterotomy and passage of glass beads. (1988) (0)
- Evaluating the Results of Clinical Trials in Inflammatory Bowel Disease: Can We Reconcile the Controversies? (1994) (0)
- Bile acids and cardiovascular complications of liver disease (1991) (0)
- Nonulcer dyspepsia: A complex spectrum of disorders. (1992) (0)
- Bariatric Surgery: A Promising Solution for Nonalcoholic Steatohepatitis in the Very Obese. (2006) (0)
- GASTRIC FLUID VOLUME AND PH: RANITIDINE ALONE VERSUS DOUBLE AND TRIPLE PROPHYLAXIS (1989) (0)
- Rising Esophageal Biopsy Rate is the Main Confounding Factor of Increasing Incidence of Eosinophilic Esophagitis: A Population Based Study (2011) (0)
- Screening for gastrointestinal disease--a critical analysis. (1990) (0)
- Screening for colorectal cancer: sample techniques. (1988) (0)
- Defective Gallbladder Contractility Associated with Increased Bile Lithogenicity in Ground Squirrels and Prairie Dogs (1984) (0)
- A Retrospective Comparison of Percutaneous Endoscopic and Radiologic Gastrostomy Tube Feeding: 1161 (2007) (0)
- Less hype, more hope. (1997) (0)
- Osteonecrosis, corticosteroid use and Crohn's disease: evidence-based medicine versus civil law. (2000) (0)
- Meta-analysis of bulking agents in the treatment of irritable bowel syndrome (2000) (0)
- Waiting for a consultation: Sorry, but the doctor cannot see you. (2012) (0)
- Eosinophilic Esophagitis Is the Leading Cause of Food Bolus Impaction Requiring Endoscopy in Calgary, Canada: 416 (2017) (0)
- Total Parenteral Nutrition (1985) (0)
- TREATMENT OF ULCERATIVE COLITIS WITH 5-AMINOSALICYCLIC ACID. RESPONSE (1993) (0)
- Cholecystokinins and the gallbladder (1980) (0)
- A perception of the irritable bowel syndrome (IBS) from physicians and pharmacist in South Australia (SA) (2003) (0)
- Endothelin-Mediated gallbladder contraction is an early event in experimental acute cholecystitis (2003) (0)
- Hepatobiliary imaging with 99mTc-labelled compounds. (1980) (0)
- Gilbert's syndrome: No longer an uptake defect? (1979) (0)
- Failure of cholesterol-lowering by psyllium (2000) (0)
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