Ennio Antonio Chiocca
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Ennio Antonio Chioccaphilosophy Degrees
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Ennio Antonio Chioccabiology Degrees
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Philosophy Biology
Ennio Antonio Chiocca's Degrees
- Doctorate Medicine University of Padua
- PhD Molecular Biology University of Padua
Why Is Ennio Antonio Chiocca Influential?
(Suggest an Edit or Addition)Ennio Antonio Chiocca's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- In vivo magnetic resonance imaging of transgene expression (2000) (779)
- Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial (2018) (754)
- microRNA-7 inhibits the epidermal growth factor receptor and the Akt pathway and is down-regulated in glioblastoma. (2008) (740)
- Targeting of the Bmi-1 oncogene/stem cell renewal factor by microRNA-128 inhibits glioma proliferation and self-renewal. (2008) (726)
- A phase I open-label, dose-escalation, multi-institutional trial of injection with an E1B-Attenuated adenovirus, ONYX-015, into the peritumoral region of recurrent malignant gliomas, in the adjuvant setting. (2004) (411)
- MicroRNA-451 regulates LKB1/AMPK signaling and allows adaptation to metabolic stress in glioma cells. (2010) (409)
- Oncolytic Viruses in Cancer Treatment: A Review (2017) (391)
- Glioblastoma in Adults: A Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) Consensus Review on Current Management and Future Directions. (2020) (367)
- Oncolytic virus therapy of multiple tumors in the brain requires suppression of innate and elicited antiviral responses (1999) (347)
- Cyclophosphamide enhances glioma virotherapy by inhibiting innate immune responses (2006) (341)
- Immune evasion mediated by PD-L1 on glioblastoma-derived extracellular vesicles (2018) (339)
- Oncolytic Viruses and Their Application to Cancer Immunotherapy (2014) (298)
- Reprogramming of the Tumor Microenvironment by Stromal Pten-regulated miR-320 (2011) (257)
- Mechanisms and therapeutic implications of hypermutation in gliomas (2020) (256)
- CAR-Engineered NK Cells Targeting Wild-Type EGFR and EGFRvIII Enhance Killing of Glioblastoma and Patient-Derived Glioblastoma Stem Cells (2015) (254)
- Isolation and characterization of cDNA clones to mouse macrophage and human endothelial cell tissue transglutaminases. (1991) (231)
- An oncolytic HSV-1 mutant expressing ICP34.5 under control of a nestin promoter increases survival of animals even when symptomatic from a brain tumor. (2005) (225)
- The Neuronal MicroRNA miR-326 Acts in a Feedback Loop with Notch and Has Therapeutic Potential against Brain Tumors (2009) (223)
- Herpes simplex virus type 1 DNA amplified as bacterial artificial chromosome in Escherichia coli: rescue of replication-competent virus progeny and packaging of amplicon vectors. (1998) (219)
- Multiplexed Profiling of Single Extracellular Vesicles. (2018) (207)
- Improved helper virus-free packaging system for HSV amplicon vectors using an ICP27-deleted, oversized HSV-1 DNA in a bacterial artificial chromosome. (2001) (192)
- Extracellular vesicles modulate the glioblastoma microenvironment via a tumor suppression signaling network directed by miR-1. (2014) (187)
- Long-term survival of rats harboring brain neoplasms treated with ganciclovir and a herpes simplex virus vector that retains an intact thymidine kinase gene. (1994) (185)
- An oncolytic viral mutant that delivers the CYP2B1 transgene and augments cyclophosphamide chemotherapy (1998) (185)
- Tumor stromal-derived factor-1 recruits vascular progenitors to mitotic neovasculature, where microenvironment influences their differentiated phenotypes. (2006) (182)
- Glioma virotherapy: effects of innate immune suppression and increased viral replication capacity. (2006) (181)
- Measuring transferrin receptor gene expression by NMR imaging. (1998) (176)
- Therapeutic efficiency and safety of a second-generation replication-conditional HSV1 vector for brain tumor gene therapy. (1997) (174)
- Effect of tumor microenvironment modulation on the efficacy of oncolytic virus therapy. (2007) (173)
- NK cells impede glioblastoma virotherapy through NKp30 and NKp46 natural cytotoxicity receptors (2012) (169)
- An infectious transfer and expression system for genomic DNA loci in human and mouse cells (2001) (165)
- microRNA-451: A conditional switch controlling glioma cell proliferation and migration (2010) (161)
- Complement Depletion Facilitates the Infection of Multiple Brain Tumors by an Intravascular, Replication-Conditional Herpes Simplex Virus Mutant (2000) (161)
- Gene transfer into experimental brain tumors mediated by adenovirus, herpes simplex virus, and retrovirus vectors. (1994) (160)
- Treatment of glioma by engineered interleukin 4-secreting cells. (1993) (159)
- Positron emission tomography-based imaging of transgene expression mediated by replication-conditional, oncolytic herpes simplex virus type 1 mutant vectors in vivo. (2001) (158)
- Immunotherapy advances for glioblastoma. (2014) (158)
- Experimental tumor therapy in mice using the cyclophosphamide-activating cytochrome P450 2B1 gene. (1994) (156)
- Depletion of peripheral macrophages and brain microglia increases brain tumor titers of oncolytic viruses. (2007) (155)
- Transfer and expression of the lacZ gene in rat brain neurons mediated by herpes simplex virus mutants. (1990) (152)
- A combinational therapy of EGFR-CAR NK cells and oncolytic herpes simplex virus 1 for breast cancer brain metastases (2016) (152)
- Synergistic anticancer effects of ganciclovir/thymidine kinase and 5-fluorocytosine/cytosine deaminase gene therapies. (1998) (149)
- In vivo 3-T MR spectroscopy in the distinction of recurrent glioma versus radiation effects: initial experience. (2002) (146)
- Central nervous system cancers. (2011) (145)
- The Long Non-coding RNA HIF1A-AS2 Facilitates the Maintenance of Mesenchymal Glioblastoma Stem-like Cells in Hypoxic Niches. (2016) (140)
- Detection of wild-type EGFR amplification and EGFRvIII mutation in CSF-derived extracellular vesicles of glioblastoma patients (2017) (136)
- Multimodal cancer treatment mediated by a replicating oncolytic virus that delivers the oxazaphosphorine/rat cytochrome P450 2B1 and ganciclovir/herpes simplex virus thymidine kinase gene therapies. (1999) (135)
- Regulatable interleukin-12 gene therapy in patients with recurrent high-grade glioma: Results of a phase 1 trial (2019) (133)
- Inhibitory CD161 receptor identified in glioma-infiltrating T cells by single-cell analysis (2021) (132)
- Phase IB study of gene-mediated cytotoxic immunotherapy adjuvant to up-front surgery and intensive timing radiation for malignant glioma. (2011) (129)
- Effects of innate immunity on herpes simplex virus and its ability to kill tumor cells (2003) (129)
- Lithium inhibits invasion of glioma cells; possible involvement of glycogen synthase kinase-3. (2008) (128)
- The molecular basis of retinoic acid action. Transcriptional regulation of tissue transglutaminase gene expression in macrophages. (1988) (125)
- Altered expression of antiviral cytokine mRNAs associated with cyclophosphamide's enhancement of viral oncolysis (2004) (125)
- Antitumor activity and reporter gene transfer into rat brain neoplasms inoculated with herpes simplex virus vectors defective in thymidine kinase or ribonucleotide reductase. (1994) (124)
- Comparison of intracerebral inoculation and osmotic blood-brain barrier disruption for delivery of adenovirus, herpesvirus, and iron oxide particles to normal rat brain. (1995) (121)
- Development of a rapid method to generate multiple oncolytic HSV vectors and their in vivo evaluation using syngeneic mouse tumor models (2006) (121)
- Glioma cell migration on three-dimensional nanofiber scaffolds is regulated by substrate topography and abolished by inhibition of STAT3 signaling. (2011) (118)
- Central nervous system cancers: Clinical Practice Guidelines in Oncology. (2005) (117)
- Phase II multicenter study of gene-mediated cytotoxic immunotherapy as adjuvant to surgical resection for newly diagnosed malignant glioma. (2015) (117)
- Phase 1 clinical trial of intratumoral reovirus infusion for the treatment of recurrent malignant gliomas in adults. (2014) (116)
- MRI of transgene expression: correlation to therapeutic gene expression. (2002) (114)
- Emerging functions of microRNAs in glioblastoma (2009) (114)
- Genetic validation of the protein arginine methyltransferase PRMT5 as a candidate therapeutic target in glioblastoma. (2014) (114)
- Histone Deacetylase Inhibitors Augment Antitumor Efficacy of Herpes-based Oncolytic Viruses. (2008) (112)
- Quantitative analysis of complex glioma cell migration on electrospun polycaprolactone using time-lapse microscopy. (2009) (111)
- An oncolytic herpes simplex virus type 1 selectively destroys diffuse liver metastases from colon carcinoma (2000) (111)
- B-myb Promoter Retargeting of Herpes Simplex Virus γ34.5 Gene-Mediated Virulence toward Tumor and Cycling Cells (1999) (110)
- Radiation-Induced Targeted Nanoparticle-Based Gene Delivery for Brain Tumor Therapy. (2019) (109)
- MicroRNA-128 coordinately targets Polycomb Repressor Complexes in glioma stem cells. (2013) (108)
- Therapeutic potential of targeting microRNA‐10b in established intracranial glioblastoma: first steps toward the clinic (2016) (108)
- MicroRNAs and glioblastoma; the stem cell connection (2010) (107)
- Primary Lymphoma of Peripheral Nerve: Report of Four Cases (2000) (105)
- Oncolytic viruses (2002) (105)
- Thymidine kinase activation of ganciclovir in recurrent malignant gliomas: a gene-marking and neuropathological study. (2000) (104)
- Brain tumor oncolysis with replication-conditional herpes simplex virus type 1 expressing the prodrug-activating genes, CYP2B1 and secreted human intestinal carboxylesterase, in combination with cyclophosphamide and irinotecan. (2005) (103)
- Enhanced antitumor efficacy of vasculostatin (Vstat120) expressing oncolytic HSV-1. (2010) (101)
- A mathematical model for pattern formation of glioma cells outside the tumor spheroid core. (2009) (100)
- Effective treatment of an orthotopic xenograft model of human glioblastoma using an EGFR-retargeted oncolytic herpes simplex virus. (2013) (100)
- A phase I trial of Ad.hIFN-beta gene therapy for glioma. (2008) (99)
- Cyclophosphamide increases transgene expression mediated by an oncolytic adenovirus in glioma-bearing mice monitored by bioluminescence imaging. (2006) (97)
- Infectious delivery of a 135-kb LDLR genomic locus leads to regulated complementation of low-density lipoprotein receptor deficiency in human cells. (2003) (97)
- Oncolysis of diffuse hepatocellular carcinoma by intravascular administration of a replication-competent, genetically engineered herpesvirus. (2000) (97)
- Enhancement of gene therapy specificity for diffuse colon carcinoma liver metastases with recombinant herpes simplex virus. (1996) (91)
- The complement response against an oncolytic virus is species-specific in its activation pathways. (2002) (86)
- Oncolytic herpes virus with defective ICP6 specifically replicates in quiescent cells with homozygous genetic mutations in p16 (2008) (85)
- Single-Step Conversion of Cells to Retrovirus Vector Producers with Herpes Simplex Virus–Epstein-Barr Virus Hybrid Amplicons (1999) (84)
- Oncolytic HSV-1 infection of tumors induces angiogenesis and upregulates CYR61. (2008) (84)
- The Histone Deacetylase Inhibitor Valproic Acid Lessens NK Cell Action against Oncolytic Virus-Infected Glioblastoma Cells by Inhibition of STAT5/T-BET Signaling and Generation of Gamma Interferon (2012) (84)
- Diffusible cytotoxic metabolites contribute to the in vitro bystander effect associated with the cyclophosphamide/cytochrome P450 2B1 cancer gene therapy paradigm. (1995) (83)
- Cancer gene therapy using a replication-competent herpes simplex virus type 1 vector. (1998) (83)
- Contribution of bone marrow-derived cells to blood vessels in ischemic tissues and tumors. (2005) (81)
- Belonging to a network--microRNAs, extracellular vesicles, and the glioblastoma microenvironment. (2015) (81)
- Pre-existing herpes simplex virus 1 (HSV-1) immunity decreases, but does not abolish, gene transfer to experimental brain tumors by a HSV-1 vector (1998) (81)
- A retrospective cohort-matched comparison of conscious sedation versus general anesthesia for supratentorial glioma resection. Clinical article. (2011) (79)
- Cyclophosphamide allows for in vivo dose reduction of a potent oncolytic virus. (2005) (78)
- Regulation of tissue transglutaminase gene expression as a molecular model for retinoid effects on proliferation and differentiation (1989) (77)
- Extracellular Vesicles from High-Grade Glioma Exchange Diverse Pro-oncogenic Signals That Maintain Intratumoral Heterogeneity. (2016) (77)
- New prodrug activation gene therapy for cancer using cytochrome P450 4B1 and 2-aminoanthracene/4-ipomeanol. (1998) (76)
- Strategies in Gene Therapy for Glioblastoma (2013) (75)
- Gene Therapy for Brain Tumors (1995) (75)
- Chondroitinase ABC I–Mediated Enhancement of Oncolytic Virus Spread and Antitumor Efficacy (2010) (74)
- Glioma virus therapies between bench and bedside. (2014) (73)
- Inhibition of NF2-negative and NF2-positive primary human meningioma cell proliferation by overexpression of merlin due to vector-mediated gene transfer. (1999) (72)
- The functional synergism of microRNA clustering provides therapeutically relevant epigenetic interference in glioblastoma (2019) (71)
- Solitary sciatic nerve lymphoma as an initial manifestation of diffuse neurolymphomatosis. Case report and review of the literature. (2000) (70)
- Enhancement of interleukin-4-mediated tumor regression in athymic mice by in situ retroviral gene transfer. (1995) (70)
- Selective uptake of viral and monocrystalline particles delivered intra-arterially to experimental brain neoplasms. (1995) (70)
- Imaging flow cytometry facilitates multiparametric characterization of extracellular vesicles in malignant brain tumours (2019) (69)
- Prodrug bioactivation and oncolysis of diffuse liver metastases by a herpes simplex virus 1 mutant that expresses the CYP2B1 transgene (2002) (68)
- Interferon-stimulated Gene 15 (ISG15) and ISG15-linked Proteins Can Associate with Members of the Selective Autophagic Process, Histone Deacetylase 6 (HDAC6) and SQSTM1/p62* (2014) (68)
- Arming an Oncolytic Herpes Simplex Virus Type 1 with a Single-chain Fragment Variable Antibody against PD-1 for Experimental Glioblastoma Therapy (2018) (68)
- Efficacy and safety of the oncolytic herpes simplex virus rRp450 alone and combined with cyclophosphamide. (2008) (67)
- Concurrent Dexamethasone Limits the Clinical Benefit of Immune Checkpoint Blockade in Glioblastoma (2020) (67)
- Genetic strategies for brain tumor therapy (2006) (67)
- Indirubins decrease glioma invasion by blocking migratory phenotypes in both the tumor and stromal endothelial cell compartments. (2011) (66)
- Oncolytic viruses driven by tumor-specific promoters. (2007) (65)
- Long-term survival in a rodent model of disseminated brain tumors by combined intrathecal delivery of herpes vectors and ganciclovir treatment. (1996) (64)
- Directing systemic oncolytic viral delivery to tumors via carrier cells. (2010) (64)
- "Buy one get one free": armed viruses for the treatment of cancer cells and their microenvironment. (2009) (64)
- Oncolytic HSV-1 virotherapy: clinical experience and opportunities for progress. (2012) (64)
- Oral tocotrienols are transported to human tissues and delay the progression of the model for end-stage liver disease score in patients. (2012) (64)
- An update on vaccine therapy and other immunotherapeutic approaches for glioblastoma (2013) (62)
- TGFβ Treatment Enhances Glioblastoma Virotherapy by Inhibiting the Innate Immune Response. (2015) (60)
- Characterization of single microvesicles in plasma from glioblastoma patients. (2018) (59)
- Antitumor efficacy of 34.5ENVE: a transcriptionally retargeted and "Vstat120"-expressing oncolytic virus. (2012) (59)
- MicroRNA Signatures and Molecular Subtypes of Glioblastoma: The Role of Extracellular Transfer (2017) (58)
- Neurosurgical Delivery of Chemotherapeutics, Targeted Toxins, Genetic and Viral Therapies in Neuro-Oncology (2004) (58)
- Co-expression of Fas and Fas ligand in malignant glial tumors and cell lines (1998) (58)
- Viral and other therapies for recurrent glioblastoma: is a 24-month durable response unusual? (2018) (58)
- Replicative oncolytic herpes simplex viruses in combination cancer therapies. (2004) (56)
- Infectious delivery of the 132 kb CDKN2A/CDKN2B genomic DNA region results in correctly spliced gene expression and growth suppression in glioma cells (2004) (56)
- PTEN decreases in vivo vascularization of experimental gliomas in spite of proangiogenic stimuli. (2003) (56)
- Cytomegalovirus contributes to glioblastoma in the context of tumor suppressor mutations. (2013) (54)
- Tissue inhibitor of metalloproteinase-3 expression from an oncolytic adenovirus inhibits matrix metalloproteinase activity in vivo without affecting antitumor efficacy in malignant glioma. (2005) (54)
- Intraarterial delivery of adenovirus vectors and liposome-DNA complexes to experimental brain neoplasms. (1999) (54)
- The effect of ganciclovir on herpes simplex virus-mediated oncolysis. (1997) (54)
- Glucose-based regulation of miR-451/AMPK signaling depends on the OCT1 transcription factor. (2015) (54)
- The multiple protective roles and molecular mechanisms of melatonin and its precursor N-acetylserotonin in targeting brain injury and liver damage and in maintaining bone health. (2019) (53)
- Histone deacetylase 6 inhibition enhances oncolytic viral replication in glioma. (2015) (53)
- Oncolytic viruses as novel anticancer agents: turning one scourge against another (2000) (52)
- Anti-angiogenic gene therapy in the treatment of malignant gliomas (2012) (51)
- Improved HSV-1 amplicon packaging system using ICP27-deleted, oversized HSV-1 BAC DNA. (2003) (50)
- Cytomegalovirus promotes murine glioblastoma growth via pericyte recruitment and angiogenesis (2019) (50)
- Cytotoxicity, apoptosis, and viral replication in tumor cells treated with oncolytic ribonucleotide reductase-defective herpes simplex type 1 virus (hrR3) combined with ionizing radiation (2000) (50)
- Gene and Viral Therapy for Glioblastoma: A Review of Clinical Trials and Future Directions (2012) (49)
- Hypofractionated versus standard radiation therapy with or without temozolomide for older glioblastoma patients. (2015) (49)
- Clinical and economic outcomes of low‐field intraoperative MRI‐guided tumor resection neurosurgery (2011) (48)
- The status of gene therapy for brain tumors (2007) (47)
- Intraneoplastic polymer-based delivery of cyclophosphamide for intratumoral bioconversion by a replicating oncolytic viral vector. (2001) (47)
- Design and application of oncolytic HSV vectors for glioblastoma therapy (2009) (47)
- Viral therapy for glioblastoma. (2003) (47)
- Stereotactic radiofrequency thermal cingulotomy for obsessive compulsive disorder. (1961) (46)
- Regulation of herpes simplex virus γ134.5 expression and oncolysis of diffuse liver metastases by Myb34.5 (2002) (46)
- Use of miRNA response sequences to block off-target replication and increase the safety of an unattenuated, glioblastoma-targeted oncolytic HSV. (2015) (46)
- The host response to cancer virotherapy. (2008) (46)
- In-training Factors Predictive of Choosing and Sustaining a Productive Academic Career Path in Neurological Surgery (2012) (45)
- Phase ib trial of oncolytic herpes virus G207 shows safety of multiple injections and documents viral replication. (2009) (43)
- Inhibition of growth and angiogenesis of human neurofibrosarcoma by heparin and hydrocortisone. (1990) (43)
- Pharmacologic and chemical adjuvants in tumor virotherapy. (2009) (42)
- Cytomegalovirus infection leads to pleomorphic rhabdomyosarcomas in Trp53+/- mice. (2012) (42)
- Comparative analyses of transgene delivery and expression in tumors inoculated with a replication-conditional or -defective viral vector. (2001) (42)
- Preclinical investigation of combined gene-mediated cytotoxic immunotherapy and immune checkpoint blockade in glioblastoma (2018) (42)
- Clinical implementation of integrated whole-genome copy number and mutation profiling for glioblastoma. (2015) (41)
- MicroRNA-10b inhibition reduces E2F1-mediated transcription and miR-15/16 activity in glioblastoma (2015) (41)
- An oncolytic herpesvirus expressing E-cadherin improves survival in mouse models of glioblastoma (2018) (41)
- The subtemporal-transpetrous approach for excision of petroclival tumors. (1996) (40)
- Escherichia coli gpt gene sensitizes rat glioma cells to killing by 6-thioxanthine or 6-thioguanine. (1996) (40)
- Intra-arterial delivery of p53-containing adenoviral vector into experimental brain tumors (2002) (40)
- Toxicity and Efficacy of a Novel GADD34-expressing Oncolytic HSV-1 for the Treatment of Experimental Glioblastoma (2018) (39)
- Oncolytic viruses for the therapy of brain tumors and other solid malignancies: a review. (2003) (39)
- Oncolytic Virus-Mediated Immunotherapy: A Combinatorial Approach for Cancer Treatment. (2015) (39)
- Histone deacetylase inhibitors augment antitumor efficacy of herpes-based oncolytic viruses. (2008) (38)
- Oncolytic viruses (2002) (38)
- Dissecting inherent intratumor heterogeneity in patient-derived glioblastoma culture models (2017) (38)
- Transgene inheritance and retroviral infection contribute to the efficiency of gene expression in solid tumors inoculated with retroviral vector producer cells. (1995) (38)
- Regulation of herpes simplex virus gamma(1)34.5 expression and oncolysis of diffuse liver metastases by Myb34.5. (2002) (37)
- The Gs-Linked Receptor GPR3 Inhibits the Proliferation of Cerebellar Granule Cells during Postnatal Development (2009) (37)
- Unique challenges for glioblastoma immunotherapy - Discussions across neuro-oncology and non-neuro-oncology experts in cancer immunology. (2020) (36)
- BKM-120 (Buparlisib): A Phosphatidyl-Inositol-3 Kinase Inhibitor with Anti-Invasive Properties in Glioblastoma (2016) (36)
- Tumor Interferon Signaling Is Regulated by a lncRNA INCR1 Transcribed from the PD-L1 Locus. (2020) (36)
- Preclinical Toxicology of rQNestin34.5v.2: An Oncolytic Herpes Virus with Transcriptional Regulation of the ICP34.5 Neurovirulence Gene (2020) (36)
- Selective delivery of herpes virus vectors to experimental brain tumors using RMP-7 (1999) (35)
- Cerebrovascular Biology and the various neural barriers: challenges and future directions. (1999) (35)
- Letter: Adaptation Under Fire: Two Harvard Neurosurgical Services During the COVID-19 Pandemic (2020) (34)
- Annexin A2 regulates angiogenesis and invasion phenotypes of malignant glioma (2014) (34)
- Extracellular Vesicles and MicroRNAs: Their Role in Tumorigenicity and Therapy for Brain Tumors (2016) (34)
- Immunotherapy for glioblastoma: on the sidelines or in the game? (2017) (34)
- Gene Therapy for Neurological Disorders and Brain Tumors (1997) (34)
- Molecular responses to immune checkpoint blockade in glioblastoma (2019) (33)
- Transglutaminases and their regulation: implications for polyamine metabolism. (1988) (32)
- Herpes vector-mediated delivery of marker genes to disseminated central nervous system tumors. (1996) (32)
- Long-term outcomes of patients with spinal cord gliomas treated by modern conformal radiation techniques. (2011) (32)
- Allergy and inflammatory transcriptome is predominantly negatively correlated with CD133 expression in glioblastoma. (2010) (32)
- Prognostic indicators. (2006) (31)
- GBM-Targeted oHSV Armed with Matrix Metalloproteinase 9 Enhances Anti-tumor Activity and Animal Survival (2019) (30)
- A novel 'piggyback' packaging system for herpes simplex virus amplicon vectors. (1996) (30)
- HSV-1 Oncolytic Viruses from Bench to Bedside: An Overview of Current Clinical Trials (2020) (30)
- The Combination of Adenoviral HSV TK Gene Therapy and Radiation is Effective in Athymic Mouse Glioblastoma Xenografts without Increasing Toxic Side Effects (2004) (29)
- C2/C3 pathologic fractures from polyostotic fibrous dysplasia of the cervical spine treated with percutaneous vertebroplasty (2007) (29)
- MicroRNA-Mediated Dynamic Bidirectional Shift between the Subclasses of Glioblastoma Stem-like Cells. (2017) (29)
- An oncolytic virus expressing a full-length antibody enhances antitumor innate immune response to glioblastoma (2021) (29)
- Imaging immediate-early and strict-late promoter activity during oncolytic herpes simplex virus type 1 infection and replication in tumors (2006) (29)
- The predictive value of low-field strength magnetic resonance imaging for intraoperative residual tumor detection. Clinical article. (2009) (29)
- A PDGFRα-driven mouse model of glioblastoma reveals a stathmin1-mediated mechanism of sensitivity to vinblastine (2018) (29)
- Growth of human schwannomas in the subrenal capsule of the nude mouse. (1990) (28)
- Retinoids as Generalized Regulators of Cellular Growth and Differentiation (1988) (28)
- Petroclival meningioma presenting with pathological laughter (1998) (28)
- Copper Chelation Enhances Antitumor Efficacy and Systemic Delivery of Oncolytic HSV (2012) (27)
- Glioblastoma infiltration of both tumor- and virus-antigen specific cytotoxic T cells correlates with experimental virotherapy responses (2020) (27)
- Extracranial growth of glioblastoma multiforme (2015) (27)
- Deciphering the Multifaceted Relationship between Oncolytic Viruses and Natural Killer Cells (2011) (26)
- Editorial. COVID-19 and academic neurosurgery (2020) (26)
- STAT3 Activation Promotes Oncolytic HSV1 Replication in Glioma Cells (2013) (25)
- Central nervous system cancers. (2011) (25)
- Potentiated gene delivery to tumors using herpes simplex virus/Epstein-Barr virus/RV tribrid amplicon vectors. (2003) (25)
- Correction: Arming an Oncolytic Herpes Simplex Virus Type 1 with a Single-chain Fragment Variable Antibody against PD-1 for Experimental Glioblastoma Therapy (2020) (25)
- Stable transgene expression from HSV amplicon vectors in the brain: potential involvement of immunoregulatory signals. (2008) (25)
- Early STAT1 activation after systemic delivery of HSV amplicon vectors suppresses transcription of the vector-encoded transgene. (2007) (25)
- Regression of experimental brain tumors with 6-thioxanthine and Escherichia coli gpt gene therapy. (1997) (25)
- The Spectrum of Vaccine Therapies for Patients With Glioblastoma Multiforme (2012) (24)
- A chimeric fusion protein of cytochrome CYP4B1 and green fluorescent protein for detection of pro-drug activating gene delivery and for gene therapy in malignant glioma. (1998) (24)
- Long-term survival in a rodent brain tumor model by bradykinin-enhanced intra-arterial delivery of a therapeutic herpes simplex virus vector. (1998) (24)
- Anticancer activity of osmium(VI) nitrido complexes in patient-derived glioblastoma initiating cells and in vivo mouse models. (2018) (24)
- Oncolytic viruses sensitize human tumor cells for NY-ESO-1 tumor antigen recognition by CD4+ effector T cells. (2018) (24)
- A Phase I Trial of Ad.hIFN-β Gene Therapy for Glioma. (2008) (24)
- Pattern formation of glioma cells: Effects of adhesion (2007) (24)
- The Fc Domain of Immunoglobulin Is Sufficient to Bridge NK Cells with Virally Infected Cells (2017) (23)
- Intraoperative MRI (ioMRI) in the setting of awake craniotomies for supratentorial glioma resection. (2011) (23)
- A retrospective analysis of reasons for reoperation following initially successful peripheral nerve stimulation. (2007) (23)
- The integrin inhibitor cilengitide enhances the anti-glioma efficacy of vasculostatin-expressing oncolytic virus (2013) (23)
- Growth of human acoustic neuromas, neurofibromas and schwannomas in the subrenal capsule and sciatic nerve of the nude mouse (1992) (22)
- Methylation markers of malignant potential in meningiomas. (2013) (22)
- Deep sylvian fissure meningioma without dural attachment in an adult: case report. (1994) (22)
- The nuclear DICER–circular RNA complex drives the deregulation of the glioblastoma cell microRNAome (2020) (22)
- Cancer immunotherapy: A vaccine from plant virus proteins. (2016) (21)
- 21 – Glioblastoma and malignant astrocytoma (2012) (21)
- KLF4K409Q–mutated meningiomas show enhanced hypoxia signaling and respond to mTORC1 inhibitor treatment (2020) (21)
- Immunotherapy for glioblastoma: going viral (2018) (21)
- Gene Therapy: A Primer for Neurosurgeons (2003) (20)
- Potential role of miRNAs and their inhibitors in glioma treatment (2010) (20)
- Physiological transgene regulation and functional complementation of a neurological disease gene deficiency in neurons. (2009) (20)
- Multicolumn infusion of gene therapy cells into human brain tumors: technical report. (2000) (19)
- Gene therapy for tumors of the central nervous system. (1998) (19)
- Modeling tumor immunity of mouse glioblastoma by exhausted CD8+ T cells (2018) (19)
- Gene therapy for glioblastoma. (2006) (18)
- DNA Demethylating Agents Synergize with Oncolytic HSV1 against Malignant Gliomas (2013) (18)
- GNOSIS: Guidelines for Neuro-Oncology: Standards for Investigational Studies — reporting of surgically based therapeutic clinical trials (2007) (18)
- Gene- and viral-based therapies for brain tumors (2009) (18)
- Evolution of malignant glioma treatment: from chemotherapy to vaccines to viruses. (2014) (18)
- Proteomic Analysis Implicates Vimentin in Glioblastoma Cell Migration (2019) (18)
- Potentiating oncolytic viral therapy through an understanding of the initial immune responses to oncolytic viral infection. (2015) (18)
- Anesthesia for brain tumor resection using intraoperative magnetic resonance imaging (iMRI) with the Polestar N-20 system: experience and challenges. (2009) (18)
- Uncovering a novel mechanism whereby NK cells interfere with glioblastoma virotherapy (2013) (17)
- FASN Is a Biomarker Enriched in Malignant Glioma-Derived Extracellular Vesicles (2020) (17)
- Modeling the effects of resection, radiation and chemotherapy in glioblastoma (2009) (17)
- COVID-19 and academic neurosurgery (2020) (17)
- Extracellular Vesicles Induce Mesenchymal Transition and Therapeutic Resistance in Glioblastomas through NF‐κB/STAT3 Signaling (2020) (17)
- Progress and prospects: gene therapy clinical trials (part 1) (2007) (17)
- Launching Effectiveness Research to Guide Practice in Neurosurgery: A National Institute Neurological Disorders and Stroke Workshop Report (2017) (17)
- Comparative effectiveness of antinociceptive gene therapies in animal models of diabetic neuropathic pain (2012) (17)
- Gene therapeutics: the future of brain tumor therapy? (2006) (17)
- Combining HDAC inhibitors with oncolytic virotherapy for cancer therapy (2015) (17)
- Development of a Function-Blocking Antibody Against Fibulin-3 as a Targeted Reagent for Glioblastoma (2017) (16)
- The many functions of microRNAs in glioblastoma. (2010) (16)
- Immune Escape Mediated by Exosomal PD‐L1 in Cancer (2020) (16)
- Glioma and microglia, a double entendre (2016) (16)
- An oncolytic herpes virus expressing E-cadherin resists NK cell clearance and improves viral spread and glioblastoma virotherapy (2018) (16)
- Mutations in glioblastoma oncosuppressive pathways pave the way for oncomodulatory activity of cytomegalovirus (2013) (16)
- Effects on brain tumor cell proliferation by an adenovirus vector that bears the interleukin-4 gene. (1998) (15)
- One size should not fit all: advancing toward personalized glioblastoma therapy. (2015) (15)
- Genetically Engineered Herpes Simplex Viral Vectors in the Treatment of Brain Tumors: A Review (2003) (14)
- Abstract 5336: Targeting glioma growth and invasiveness by microRNA-1. (2013) (14)
- Development of a novel non-human primate model for preclinical gene vector safety studies. Determining the effects of intracerebral HSV-1 inoculation in the common marmoset: a comparative study (2003) (14)
- How much is enough? The question of extent of resection in glioblastoma multiforme. (2014) (14)
- In vitro screening of clinical drugs identifies sensitizers of oncolytic viral therapy in glioblastoma stem-like cells (2015) (13)
- Expression of HSV-1 Receptors in EBV-Associated Lymphoproliferative Disease Determines Susceptibility to Oncolytic HSV (2012) (13)
- Viruses in cancer therapy — from benchwarmers to quarterbacks (2018) (13)
- Toxicology and Biodistribution Studies for MGH2.1, an Oncolytic Virus that Expresses Two Prodrug-activating Genes, in Combination with Prodrugs (2013) (13)
- Gene expression profiling of the anti-glioma effect of Cilengitide (2013) (13)
- Estimating the cell density and invasive radius of three-dimensional glioblastoma tumor spheroids grown in vitro. (2007) (13)
- Novel animal glioma models that separately exhibit two different invasive and angiogenic phenotypes of human glioblastomas. (2012) (12)
- Marker Gene Transfer and Oncolysis of Human Y79 Retinoblastoma Cells Mediated by Herpes simplex Virus Mutants (1998) (12)
- Experimental therapies: gene therapies and oncolytic viruses. (2016) (12)
- Current State of Immune-Based Therapies for Glioblastoma. (2016) (12)
- Targeting glioma-initiating cells via the tyrosine metabolic pathway. (2020) (12)
- Modification of HSV-1 to an oncolytic virus. (2014) (12)
- Neurogenetic surgery: current limitations and the promise of gene- and virus-based therapies. (1999) (11)
- Reversal of neurological deficit after chemotherapy in BCL-6-positive neurolymphomatosis. Case report. (2009) (11)
- Letter: When Less is More: Dexamethasone Dosing for Brain Tumors. (2019) (11)
- Virus-Mediated Genetic Treatment of Rodent Gliomas (1994) (11)
- Nerve growth factor protects against herpes simplex virus type 1 neurotoxicity in the rat striatum. (1994) (11)
- Cytochrome p450-based gene therapies for cancer. (2004) (11)
- Oncolytic viruses targeting tumor stem cells. (2014) (10)
- Pharmacologic and Chemical Adjuvants in Tumor Virotherapy (2009) (10)
- Expanded phase I study of intratumoral Ad-RTS-hIL-12 plus oral veledimex: Tolerability and survival in recurrent glioblastoma. (2017) (9)
- Editorial: Glioblastoma multiforme and laser interstitial thermal therapy. (2013) (9)
- Switching a Replication-Defective Adenoviral Vector into a Replication-Competent, Oncolytic Adenovirus (2013) (9)
- AI boosted molecular MRI for apoptosis detection in oncolytic virotherapy (2020) (9)
- Gliomas and venous thromboembolism: how common? (2007) (9)
- Human Cytomegalovirus is Present in Alveolar Soft Part Sarcoma (2017) (9)
- Association between shunt-responsive idiopathic normal pressure hydrocephalus and alcohol. (2017) (9)
- Retinoid--regulated expression of tissue transglutaminase in normal and leukemic myeloid cells. (1988) (8)
- Oncolytic HSV Vectors and Anti-Tumor Immunity. (2020) (8)
- Frameless Stereotactic Navigation during Insular Glioma Resection using Fusion of Three-Dimensional Rotational Angiography and Magnetic Resonance Imaging: A Technical Note. (2019) (8)
- Redesigned reporter gene for improved proton exchange-based molecular MRI contrast (2020) (8)
- Massive growth of a meningioma into the brachial plexus and thoracic cavity after intraspinal and supraclavicular resection. Case report and review of the literature. (2002) (8)
- Brain Tumor Imaging and Surgical Management: The Neurosurgeon's Perspective (2006) (8)
- An HSV amplicon-based helper system for helper-dependent adenoviral vectors. (2003) (8)
- Hypoxic Roadmap of Glioblastoma—Learning about Directions and Distances in the Brain Tumor Environment (2020) (8)
- Therapeutic cancer vaccines for pediatric malignancies: advances, challenges, and emerging technologies (2021) (8)
- ICP0 inhibits the decrease of HSV amplicon-mediated transgene expression. (2009) (7)
- Adult Tethered Cord Syndrome Following Chiari Decompression. (2018) (7)
- Extent of resection. (2011) (7)
- Response to energy depletion: miR-451/AMPK loop (2015) (7)
- Oncolytic viruses on the cusp of success?: proceedings of the 9th International Conference on Oncolytic Virus Therapeutics (2016) (7)
- Solitary pituitary sarcoidosis with normal endocrine function: case report. (2008) (6)
- Oncolytic Virus Therapy Alters the Secretome of Targeted Glioblastoma Cells (2021) (6)
- Modeling Cytomegalovirus Infection in Mouse Tumor Models (2015) (6)
- Gene therapy of brain tumors: problems presented by physiological barriers (2000) (6)
- Experimental and Clinical Gene Therapies for Brain Tumors (1998) (6)
- Perioperative mortality. (2012) (6)
- National Institute of Neurological Disorders and Stroke: current funding status, opportunities, challenges, emerging scientific advances, and recommendations for neurosurgery. (2020) (6)
- Effect of controlled intratumoral viral delivery of Ad-RTS-hIL-12 + oral veledimex in subjects with recurrent or progressive glioma. (2016) (6)
- 885 Braingate: Turning Thought into Action-First Experience with a Human Neuromotor Prosthesis. (2005) (6)
- Targeting Glioblastoma Using a Novel Peptide Specific to a Deglycosylated Isoform of Brevican (2021) (6)
- Understanding glioma invasion: a necessity for effective therapy. (2013) (6)
- Prognosis and treatment of melanoma metastases to the central nervous system: lots of retrospective data, very few certainties. (2011) (5)
- Skull base chordomas and chondrosarcomas: a population-based analysis. (2015) (5)
- Finding drugs against CD133+ glioma subpopulations. (2011) (5)
- Being old is no fun: treatment of glioblastoma multiforme in the elderly. (2008) (5)
- From localization to pathways: the continuing evolution of diffusion tensor imaging. (2014) (5)
- Pneumatosis intestinalis after molecular targeted therapy. (2019) (5)
- Personalizing oncolytic virotherapy? (2007) (5)
- Intra-arterial virus and nonvirus vector-mediated gene transfer to experimental rat brain tumors. (1999) (5)
- Awake Craniotomy and Intraoperative MRI for Maximal Safe Resection in a Case of an Extensive Left Frontal and Insular Low-grade Glioma: 3-Dimensional Operative Video. (2015) (5)
- Tumor-Associated Macrophages/Microglia in Glioblastoma Oncolytic Virotherapy: A Double-Edged Sword (2022) (4)
- Bringing the endovascular neurosurgeon into the neuro-oncology treatment team. (2012) (4)
- Multiple craniotomies. (2011) (4)
- IT-05ADMINISTRATION OF TOCA 511 TO SUBJECTS WITH RECURRENT HGG UNDERGOING REPEAT RESECTION. (2014) (4)
- Editorial: meningioma and radiotherapy. (2012) (4)
- A conditional switch controlling glioma cell proliferation and migration (2010) (4)
- Guided genes for tumor warfare (2002) (4)
- Reconstruction of Rare Skull Metastases Using Free Latissimus Dorsi Flap and the Role of Preoperative Embolization in Hypervascular Skull Tumors (2015) (4)
- "Infectious" optimism for treatment of hepatocellular carcinoma. (2013) (4)
- A review of gene therapy for the treatment of central nervous system tumors. (1999) (4)
- Nanotechnology-based strategies for the diagnosis and treatment of intracranial neoplasms. (2013) (4)
- IMPS-03INTRATUMORAL REGULATED EXPRESSION OF IL-12 AS A GENE THERAPY APPROACH TO TREATMENT OF GLIOMA (2015) (3)
- Measuring versus seeing. (2011) (3)
- The HSV-1 iBAC amplicon vector for functional genomics studies into the genetic mechanisms of neurodegenerative disease (2004) (3)
- Do meningioma patients benefit from antiepileptic drug treatment? (2013) (3)
- A cross-talk network that facilitates tumor virotherapy (2015) (3)
- Angiogenesis and Invasion (2010) (3)
- Oncolytic viruses: extreme treatment for an extreme disease. (2006) (3)
- Controlled IL-12 in combination with a PD-1 inhibitor subjects with recurrent glioblastoma. (2020) (3)
- Evaluation of controlled IL-12 in combination with a PD-1 inhibitor in subjects with recurrent glioblastoma. (2019) (3)
- A viral strategy to ambush tumors (2011) (3)
- Treatment for paragangliomas: passing the test of time. (2012) (3)
- IMMUNOTHERAPY/BIOLOGICAL THERAPIES (2013) (3)
- CTNI-12. PRELIMINARY RESULTS OF THE ABEMACICLIB ARM IN THE INDIVIDUALIZED SCREENING TRIAL OF INNOVATIVE GLIOBLASTOMA THERAPY (INSIGHT): A PHASE II PLATFORM TRIAL USING BAYESIAN ADAPTIVE RANDOMIZATION (2020) (2)
- DDEL-06PRELIMINARY SAFETY OF TOCA 511, A RETROVIRAL REPLICATING VECTOR, IN PATIENTS WITH RECURRENT HIGH GRADE GLIOMA ACROSS THREE SEPARATE PHASE 1 STUDIES (2015) (2)
- Use of 5-aminolevulinic acid for visualization of low-grade gliomas. (2011) (2)
- Neurosurgery Research and Education Foundation funding conversion to National Institutes of Health funding. (2021) (2)
- CTNI-11. CC-115 IN NEWLY DIAGNOSED MGMT UNMETHYLATED GLIOBLASTOMA IN THE INDIVIDUALIZED SCREENING TRIAL OF INNOVATIVE GLIOBLASTOMA THERAPY (INSIGHT): A PHASE II RANDOMIZED BAYESIAN ADAPTIVE PLATFORM TRIAL (2020) (2)
- Brain tumor gene therapy in mice with a novel "suicide" gene: the cyclophosphamide-activating CYP2B1 gene. (1995) (2)
- Adult cerebellar glioblastomas: a distinct entity or parcel of the whole? (2013) (2)
- The emerging field of oncolytic virus-based cancer immunotherapy. (2022) (2)
- Stage IV melanoma. (2012) (2)
- Meningioma surgery. (2011) (2)
- Evolution of the Neurosurgeon's Role in Clinical Trials for Glioblastoma: A Systematic Overview of the Clinicaltrials.Gov Database (2021) (2)
- Hope and challenges for dendritic cell-based vaccine therapy for glioblastoma. (2012) (2)
- Abstract 1584: Targeting protein arginine methyltransferase 5 (PRMT5) enzyme over expression in high grade astrocytomas (2010) (2)
- Superficial greater petrosal neuropathy. (2014) (2)
- Gene Therapy for the Nervous System-Status (1995) (2)
- Chapter 14 – Cerebellar Tumors in Adults (2012) (2)
- ATIM-15. A PHASE 1 STUDY OF Ad-RTS-hIL-12 + VELEDIMEX IN ADULTS WITH RECURRENT GLIOBLASTOMA: DOSE DETERMINATION WITH UPDATED OVERALL SURVIVAL (2018) (2)
- Brain Tumors and Gliomas (2013) (2)
- Editorial: radiosurgery and atypical meningiomas. (2012) (2)
- CELL BIOLOGY AND SIGNALING (2010) (2)
- CHAPTER 22 – Prodrug-Activation Gene Therapy (2006) (2)
- Introduction: a focus on low-grade glioma. (2015) (2)
- Neural expression of G protein-coupled receptors GPR3 modulates survival of neurons under hypoxic conditions (2010) (2)
- Positron Emission Tomography-based Imaging of Transgene Expression Mediated by Replication-conditional , Oncolytic Herpes Simplex Virus Type 1 Mutant Vectors in Vivo 1 (2001) (2)
- Convection-enhanced delivery. (2012) (2)
- Von Hippel-Lindau disease and pregnancy. (2012) (2)
- EXPERIMENTAL THERAPEUTICS AND PHARMACOLOGY (2013) (2)
- Cerebrovascular biology and the various neural barriers (1999) (2)
- Editorial: Intraoperative magnetic resonance spectroscopy and gliomas. (2013) (2)
- Neoplasm development after stereotactic radiosurgery for arteriovenous malformations. (2014) (2)
- Biographies of international women leaders in neurosurgery. (2021) (2)
- Editorial: dural tail sign. (2012) (2)
- Low Karnofsky Performance Scale score and glioblastoma multiforme. (2011) (2)
- Hypofractionated (HRT) versus standard (SRT) radiotherapy with or without temozolomide (T) for elderly patients with glioblastoma (GBM). (2014) (1)
- LAB-CELL BIOLOGY AND SIGNALING (2012) (1)
- ATIM-26. A PHASE 1 STUDY OF Ad-RTS-hIL-12 + VELEDIMEX IN ADULT RECURRENT GLIOBLASTOMA. (2017) (1)
- 434. Oncolytic Virotherapy Using the HSV Mutant rQNestin34.5 towards CD133+ Brain Tumor Stem Cells (2006) (1)
- Increased Viral Replication Capacity Glioma Virotherapy : Effects of Innate Immune Suppression (2006) (1)
- IMMU-09. CONCURRENT DEXAMETHASONE LIMITS THE CLINICAL BENEFIT OF IMMUNE CHECKPOINT BLOCKADE IN GLIOBLASTOMA (2020) (1)
- Current State of Immune-Based Therapies for Glioblastoma. (2016) (1)
- Virus Vector-Mediated Transfer of Drug-Sensitivity Genes for Experimental Brain Tumor Therapy (1995) (1)
- Editorial: postoperative ischemia. (2013) (1)
- Modulation of Natural Killer Cell Activity in the Setting of Oncolytic Virotherapy and with a Chimeric Antigen Receptor (2015) (1)
- Image-guided maximal resection of intrinsic tumors. (2014) (1)
- iBAC Technologies for Neurological Disease (2016) (1)
- Acknowledgement of Reviewers 2012 (2013) (1)
- Frontal dermoid cyst coexisting with suprasellar craniopharyngioma: a spectrum of ectodermally derived epithelial-lined cystic lesions? (2016) (1)
- The Role of Radiation Therapy in Gross Totally Resected Meningiomas. (2015) (1)
- Influence of p53 status on the efficacy of HSV-mediated cancer gene therapy (1998) (1)
- Endoscopic Endonasal Resection of a Suprasellar Pituitary Adenoma Mimicking Tuberculum Sellae Meningioma in a Patient with an Intrasellar Persistent Trigeminal Artery (2018) (1)
- Ascending dose trials of a retroviral replicating vector (Toca 511) in patients with recurrent high-grade glioma. (2014) (1)
- BTP-7, a novel peptide for therapeutic targeting of malignant brain tumors (2020) (1)
- Treating glioblastoma multiforme with electrical fields. (2010) (1)
- Gs-linked receptor GPR3 modulates proliferation and differentiation of cerebellar granule cell precursors (2009) (1)
- [Herpes simplex type-1 virus-based vectors for gene therapy]. (2000) (1)
- Abstract PR04: The role of long noncoding RNA HIF1A-AS2 in hypoxic environment of glioblastoma (2016) (1)
- DDIS-19. NOVEL PEPTIDE HOMING TO GLIOMA-SPECIFIC ISOFORM OF BREVICAN SELECTIVELY TARGETS MALIGNANT BRAIN TUMORS (2017) (1)
- LAB-EXPERIMENTAL (PRE-CLINICAL) THERAPEUTICS AND PHARMACOLOGY (2012) (1)
- Monoclonal antibodies. (2010) (1)
- No free lunch: secondary neoplasms after stereotactic radiation. (2015) (1)
- OMICS AND PROGNSTIC MARKERS (2013) (1)
- LAB-EXPERIMENTAL (PRE-CLINICAL) THERAPEUTICS AND PHARMACOLOGY (2012) (1)
- Lower-Dose Stereotactic Radiosurgery for Small Brain Metastases: Local Control and Toxicity (2014) (1)
- Cytomegalovirus Encephalopathy during Brain Tumor Irradiation (2020) (1)
- Academic productivity in today's training climate: a fellowship's impact. (2015) (1)
- Clinical Trials of Oncolytic Viruses for Gliomas (2007) (1)
- Final results of controlled IL-12 monotherapy in adults with grade III or IV gliomas. (2020) (1)
- LAB-CELL BIOLOGY AND SIGNALING (2012) (1)
- The iBAC: an efficient high capacity genomic DNA expression system. (2002) (1)
- Malignant Glioma without Affecting Antitumor Efficacy in In vivo Activity Oncolytic Adenovirus Inhibits Matrix Metalloproteinase Tissue Inhibitor of Metalloproteinase-3 Expression from an Updated (2005) (1)
- PRECLINICAL EXPERIMENTAL THERAPEUTICS AND PHARMACOLOGY (2010) (0)
- GENT-20. THE ROLE OF MIR-128 AND POLYCOMB REPRESSOR COMPLEXES IN RADIATION INDUCED PRONEURAL TO MESENCHYMAL SUBTYPE TRANSITION IN GLIOBLASTOMA STEM CELLS (2016) (0)
- The Current Approach to Precocious Puberty: Consensus 2012 (2012) (0)
- 591 Comparison of two oHSV Vectors for the treatment of glioblastoma (2020) (0)
- [Gene therapy for brain tumors: gene therapy for malignant brain tumors using prodrug-sensitivity genes (series 4)]. (1994) (0)
- High capacity viral vectors for genomic DNA transgene delivery: Applications to gene therapy and functional genomics (2004) (0)
- Advances in Brief Intraneoplastic Polymer-based Delivery of Cyclophosphamide for Intratumoral Bioconversion by a Replicating Oncolytic Viral Vector 1 (2001) (0)
- 158. Real-Time Visualization of Neuronal Differentiation and Neurite Projection Using an Indicator HSV Amplicon Vector (2006) (0)
- Preoperative comorbidity scores and intangible neurosurgical wisdom. (2011) (0)
- Abstract CT110: Phase II multicenter study of gene-mediated cytotoxic immunotherapy as an adjuvant to surgical resection for newly diagnosed malignant glioma: lessons learned from pseudo-progression and a nine-year survivor (2016) (0)
- Clustering of brain tumor cells: a first step for understanding tumor recurrence (2012) (0)
- Abstract 1383: The effect of a novel angiogenesis inhibitor (TM) on the efficacy of HSV-1 oncolytic virus (2010) (0)
- Neurosurgical "pearls" and neurosurgical evidence. (2010) (0)
- Integrative Copy Number and Mutational Analysis Improves Glioma Diagnostics (2014) (0)
- A PDGFRα-driven mouse model of glioblastoma reveals a stathmin1-mediated mechanism of sensitivity to vinblastine (2018) (0)
- Abstract B84: Preclinical analysis of combinatorial glioblastoma therapy with the prodrug-mediated gene therapy vector AdV-TK and immune checkpoint inhibition (2017) (0)
- The current state of glioma data registries. (2022) (0)
- INNV-13. ALLELE: A CONSORTIUM FOR PROSPECTIVE GENOMICS AND FUNCTIONAL DIAGNOSTICS TO GUIDE PATIENT CARE AND TRIAL ANALYSIS IN NEWLY-DIAGNOSED GLIOBLASTOMA (2018) (0)
- Who benefits from surgery for brain metastases? (2014) (0)
- 395 Detection of viral antigen and immune activation after intra-tumor injection of CAN-3110 (ICP-34.5 expressing HSV-1 oncolytic virus) in patients with recurrent high-grade glioma (2021) (0)
- The Neurosurgery Healthcare Team (2015) (0)
- 802. Rapid Conversion of HSV Resistant Cells to Sensitive Cells Using AdV-Mediated Overexpression of HSV Receptors (2004) (0)
- Abstract 1514: Oncolytic viral therapy for glioblastoma induces robust natural killer cell activation (2010) (0)
- CTIM-09. ENRICHED TCR/BCR VDJ REARRANGEMENTS CORRELATE WITH MRI AND SURVIVAL OUTCOMES IN PATIENTS WITH RECURRENT HIGH-GRADE GLIOMA TREATED WITH CAN-3110 (2022) (0)
- Meningioma-toward an improved understanding of the role of sex steroids in tumor development and progression. (2011) (0)
- Genomic Evaluation of Brain Tumors and Gliomas (2010) (0)
- Cancer Therapy: Preclinical CopperChelationEnhancesAntitumorEfficacyandSystemic Delivery of Oncolytic HSV (2012) (0)
- TMOD-14. A PATIENT-DERIVED CANCER CELL LINE ATLAS OF PRIMARY AND METASTATIC CENTRAL NERVOUS SYSTEM TUMORS (2018) (0)
- Abstract 5009: Translational efficacy of oncolytic HSV-1 in glioblastoma using a human autologousex vivoplatform, CANscript™ (2019) (0)
- IMMU-12. THE HISTONE DEACETYLASE INHIBITOR VALPROIC ACID AUGMENTS THE SUSCEPTIBILITY OF ONCOLYTIC VIRUS-INFECTED GLIOBLASTOMA CELLS TO PD-1 BLOCKADE THERAPY (2017) (0)
- Adverse Events in Multimodal Treatment Therapies for High-Grade Gliomas (2011) (0)
- Abstract 4815: Cytomegalovirus enhances glioblastoma via PDGF-B/STAT3 pathway activation (2012) (0)
- Editorial: urinary tract infection. (2012) (0)
- Targeting Gamma34.5-mediated Herpes Virulence for Tumor Therapy (1999) (0)
- Quantitative Analysis of Surgical Exposure and Angle of Surgical Freedom Obtained by Endoscope and Microscope in the Retrosigmoid and Various Posterior Petrosectomy Approaches to the Petroclival Region Using CT-Based Frameless Stereotaxy (2008) (0)
- Uchida13MT-Suppl 1 (2013) (0)
- IMMU-02. ONCOLYTIC HSV THERAPY ENHANCES GLIOBLASTOMA CONTROL VIA THE EXPANSION OF FUNCTIONAL TUMOR-SPECIFIC T CELLS AND MODULATION OF MYELOID CELL POPULATION (2018) (0)
- Editorial: the management of low-grade glioma in adults. (2015) (0)
- TMOD-03. PAN-CANCER ANALYSIS OF ORTHOTOPIC PATIENT DERIVED XENOGRAFTS FROM BRAIN METASTASES (2020) (0)
- CopperChelationEnhancesAntitumorEfficacyandSystemic Delivery of Oncolytic HSV (2012) (0)
- Abstract A075: Preclinical analysis of combinatorial glioblastoma therapy with the prodrug-mediated gene therapy vector AdV-TK and immune checkpoint inhibition in GBM therapy (2016) (0)
- Tannous et al. Respond. (2009) (0)
- Low-grade gliomas and quality of life. (2014) (0)
- ET-27REPLICATION AND SPREAD OF ONCOLYTIC HERPES VIRUS IN GLIOMA STEM CELLS CAN BE ENHANCED BY SPECIFIC INHIBITION OF HISTONE DEACETYLASE 6 (2014) (0)
- EXTH-69. AN ENGINEERED microRNA CLUSTER FOR BROAD TARGETING OF EPIGENETIC COMPLEXES IN GBM (2017) (0)
- The Role of Long Noncoding RNAs in Glioblastoma: What the Neurosurgeon Should Know. (2023) (0)
- Imaging of gene therapy: basis and clinical trials (2009) (0)
- Brain Surgery for Elders (2010) (0)
- Stereotactic radiosurgery and atypical meningiomas. (2013) (0)
- Evaluation of controlled IL-12 as monotherapy in subjects with recurrent GBM. (2019) (0)
- DDIS-12. A FACILE, ROBUST AND PREDICTIVE IN VITRO BLOOD-BRAIN-BARRIER MODEL FOR HIGH-THROUGHPUT SCREENING AND DISCOVERY OF BRAIN-PENETRATING AGENTS (2016) (0)
- The Evolving Role of Neurosurgical Intervention for Central Nervous System Tumors. (2021) (0)
- [Molecular imaging of transgene expression in brain tumors]. (2004) (0)
- Abstract Submitted for the MAR07 Meeting of The American Physical Society Pattern formation of glioma cells: effects of adhesion EVGENIY (2012) (0)
- 432. Aurora A Kinase Inhibition Enhances Oncolytic Herpes Simplex Virotherapy in Models of Neuroblastoma (2015) (0)
- Uchida13MT-Suppl 3 (2013) (0)
- CTIM-28. PHASE 2 TRIAL OF CONTROLLED IL-12 IN COMBINATION WITH PD-1 INHIBITOR IN ADULT SUBJECTS WITH RECURRENT GLIOBLASTOMA (rGBM) (2020) (0)
- NT-08A NOVEL HIGH-THROUGHPUT MICROFLUIDIC DEVICE DESIGNED TO ACCELERATE THE DISCOVERY OF GLIOBLASTOMA-TARGETING LIGANDS FROM OBOC LIBRARIES (2014) (0)
- Uchida13MT-Suppl 2 (2013) (0)
- Modulation of tumor microenvironment enhances oncolytic virus therapy (2007) (0)
- Adenoviral-mediated gene transfer into the canine brain in vivo. Commentary (2007) (0)
- Demonstration of anti-tumor immunity via intratumoral regulated platform ad-RTS-hIL-12 in advanced breast cancer and recurrent glioblastoma patients. (2018) (0)
- LAB-STEM CELLS (2012) (0)
- STEM-09MicroRNA-128 IS A MASTER SWITCH BETWEEN PRONEURAL AND MESENCHYMAL SUBTYPE IN GLIOBLASTOMA STEM CELLS (2015) (0)
- Abstract LB-293: Indirubins decrease glioma growth and invasionin vivo:A novel treatment paradigm combining antimigratory and antiangiogenic effects (2010) (0)
- Abstract 2349: Evaluation of the combination of the prodrug-mediated gene therapy vector AdV-tk and immune checkpoint inhibitor for glioblastoma treatment in a syngeneic mouse model (2016) (0)
- 2. Gene Therapy for Malignant Glioma(Special Lecture,PS2-3 Future of Glioma Therapy,Plenary Session,The 29th Annual Meeting of The Japanese Congress of Neurological Surgeons) (2009) (0)
- Abstract PO089: Comparison of Two oHSV Vectors for the Treatment of Glioblastoma (2021) (0)
- Role of surgery for glioblastoma: response to letters from Dr. Gerritsen and his colleagues and Dr. Vargas Lopez. (2021) (0)
- PATH-03. CLINICAL UTILITY OF NEXT GENERATION SEQUENCING IN IDH-WILDTYPE GLIOBLASTOMA: THE DANA-FARBER CANCER INSTITUTE EXPERIENCE (2020) (0)
- Abstract 2990: Antigen presentation deficiency and mesenchymal differentiation underlie resistance to immunotherapy in the murine syngeneic CT2A tumor model (2023) (0)
- IMPS-21EFFECT OF rQNestin 34.5 ONCOLYTIC HERPES VIRUS ON IMMUNE CHECKPOINT GENE EXPRESSION IN GLIOBLASTOMA CELLS AND EVALUATION OF THERAPEUTIC EFFICACY (2015) (0)
- Mechanism of specific infection and destruction of diffuse liver metastases by a replication-competent herpes simplex virus (2000) (0)
- Stroke and heart disease: the "also-rans" of radiation exposure. (2011) (0)
- Performing quality research in an era of reforms. (2011) (0)
- EXTH-38. A TRIPLET BIOLUMINESCENCE IMAGING SYSTEM REAL-TIME REVEALS VIRAL INFECTION, REPLICATION AND TUMOR VIABILITY IN VIVO (2016) (0)
- Abstract 299: In vitro compound screening identifies enhancers of adenoviral oncolysis with Delta24-RGD in patient-derived glioblastoma stem cells (2015) (0)
- Targeting Glioblastoma Invasion with GSK-3 inhibitors: Rapid Effects on the EMT Marker Vimentin (2014) (0)
- Abstract LB-B19: BKM-120: a phosphatidyl-inositol-3 kinase inhibitor with anti-migratory properties in glioblastoma (2015) (0)
- TMOD-26. CYTOMEGALOVIRUS PROMOTES GLIOBLASTOMA GROWTH VIA PDGF-D DRIVEN PERICYTE RECRUITMENT AND ANGIOGENESIS (2018) (0)
- Oncolytic HSV therapy sensitizes glioma cells to integrin antagonists in vitro and in vivo. (2008) (0)
- WHO classifi cation of central nervous system tumors 2016 : integration of histological features and molecular biomarkers for improved glioma diagnostics (2016) (0)
- Identification of changes in tumor secretome upon OV therapy (2007) (0)
- ATPS-98MONITORING ONCOLYTIC HSV-1 WITH NON-INVASIVE BIOLUMINESCENCE. (2015) (0)
- Herpes Simplex Virus 1 for Cancer Therapy (2010) (0)
- BI-03GLIOBLASTOMA-SPECIFIC AND GLIOBLASTOMA STEM CELL SUBTYPE-SPECIFIC SIGNATURES OF LONG, NON-CODING RNAs (2014) (0)
- DDIS-26. BTP-7, A NOVEL PEPTIDE FOR THERAPEUTIC TARGETING OF MALIGNANT BRAIN TUMORS (2018) (0)
- Gene-Based and Viral-Based Therapies (2005) (0)
- Abstract 1433: Analysis of tumor cell migration on electrospun nanofibers identifies STAT3 as a pro-migratory target in gliomas (2011) (0)
- EXTH-23. PRECLINICAL ANALYSIS OF COMBINATORIAL GLIOBLASTOMA THERAPY WITH THE PRODRUG-MEDIATED GENE THERAPY VECTOR AdV-tk AND IMMUNE CHECKPOINT INHIBITION (2016) (0)
- The molecular mechanism of retinoic acid action: Regulation of tissue transglutaminase gene expression (1988) (0)
- AI-010. ACTIVATION OF THE PROTOTYPICAL SFK C-Src PROMOTES ANGIOGENESIS OF HUMAN GLIOBLASTOMA (2013) (0)
- Oncolytic Viral Therapy for Glioma (2005) (0)
- Introduction. Gene and viral therapy for glioblastoma multiforme (2021) (0)
- ALLELE: A consortium for prospective genomics and functional diagnostics to guide patient care and trial analysis in newly-diagnosed glioblastoma. (2018) (0)
- ATIM-32. PERSONALIZED NEOANTIGEN-TARGETING VACCINE GENERATES ROBUST SYSTEMIC AND INTRATUMORAL T CELL RESPONSES IN GLIOBLASTOMA (GBM) PATIENTS (2018) (0)
- 657. Combination Therapy with Cyclophosphamide and the Oncolytic Herpes Virus Mutant rRp450, Expressing a Cyclophosphamide Prodrug, Is Clinically Safe by Intratumoral, Intravenous, and Intracerebral Administration in an HSV-1 Susceptible Mouse Model (2006) (0)
- CBMT-12. FATTY ACID SYNTHASE POSITIVE EVs AS NOVEL BIOMARKERS IN BRAIN CANCER. (2018) (0)
- IMST-21. GLIOBLASTOMA-DERIVED EXTRACELLULAR VESICLES DYNAMICALLY CARRY PDL1 AND SPECIFICALLY INHIBIT CD4+ AND CD8+ T-CELL ACTIVATION AND PROLIFERATION (2016) (0)
- Virotherapy treatment of central nervous system tumors (2022) (0)
- Primary Lymphoma of Peripheral Nerve (2000) (0)
- Nonreplicating Glioma Cells Support Oncolytic Herpes Replication If They Carry Specific Oncogene Deletions (2007) (0)
- Gene- and Viral-Based Therapies for Gliomas (2011) (0)
- Mir-128 CONTROLS THE ACTIVITY OF EPIGENETIC REGULATORS PRC1 AND PRC2 IN NEURAL STEM CELLS: IMPLICATIONS OF ITS LOSS IN GLIOMAGENESIS (2013) (0)
- The biology of tumor cell invasion in the brain and its therapy (2013) (0)
- Predicting outcomes: recursive partitioning analysis (RPA) prognostic algorithm for patients with metastatic sarcoma to the brain. (2014) (0)
- Molecular and genetic characterization of meningiomas: future predictive assays and "personalized" treatment. (2013) (0)
- IMST-05. NOVEL CAR-T CELLS TARGETING THE EXTRACELLULAR MATRIX OF GLIOBLASTOMA INDUCE STRONG ANTI-TUMOR IMMUNE RESPONSE (2016) (0)
- CBIO-12. SIX EXTRACELLULAR VESICLE RELATED GENES CAN EXPLAIN THE PRO-TUMORIGENIC BEHAVIOR OF HETEROGENEOUS HIGH GRADE GLIOMAS (2016) (0)
- CBM-01CHARACTERIZATION OF microRNAome IN GLIOBLASTOMA STEM CELLS AND THEIR EXTRACELLULAR VESICLES (2015) (0)
- 20 – Infratentorial and Cerebellar Tumors (2018) (0)
- Deep CEST MR Fingerprinting at 7T Reveals Tumor Apoptotic Response to Oncolytic Virotherapy In Vivo (2020) (0)
- Irinotecan , in Combination with Cyclophosphamide Carboxylesterase Secreted Human Intestinal and CYP 2 B 1 Genes , Simplex Virus Type 1 Expressing the Prodrug-Activating Brain Tumor Oncolysis with Replication-Conditional Herpes (2005) (0)
- IMMU-10. EXPRESSION OF PD-L2, IN GLIOBLASTOMA; IMPLICATIONS AS A BIOMARKER FOR IMMUNOTHERAPY (2017) (0)
- TMOD-20. ESTABLISHMENT OF A BRAIN TUMOR MODEL WITH DYSFUNCTIONAL TUMOR IMMUNITY IN MICE AS A PLATFORM FOR IMMUNOTHERAPEUTIC EVALUATION (2016) (0)
- 804. Expression of Green Fluorescent Protein Modifies the Antitumor Effect of Oncolytic HSV-1 Vectors (2004) (0)
- 18. ALLELE: A consortium for prospective genomics and functional diagnostics to guide patient care and trial analysis in newly-diagnosed glioblastoma (2018) (0)
- CHAPTER 79 – Genomic Medicine, Brain Tumors and Gliomas (2009) (0)
- ET-42DEVELOPMENT OF A NOVEL, FUNCTION-BLOCKING ANTI-FIBULIN-3 ANTIBODY AS TARGETED REAGENT FOR GLIOBLASTOMA (2014) (0)
- P01.24 Rapid adaptation to metabolic stress depend on microRNA expression in Glioma (2017) (0)
- Early Detection of Tumor Apoptotic Response to Oncolytic Virotherapy using Deep CEST MR Fingerprinting (2020) (0)
- EVER, European Association for Vision and Eye Research (1998) (0)
- Immunotherapy for glioblastoma: going viral (2018) (0)
- Amendments: Publisher Correction: An oncolytic herpesvirus expressing E-cadherin improves survival in mouse models of glioblastoma (2019) (0)
- ATPS-08DISCOVERY OF NOVEL GLIOMA-TARGETING PEPTIDES USING A HIGH-THROUGHPUT MICROFLUIDIC MAGNETIC-ACTIVATED SORTER (2015) (0)
- The 1994 National Cancer Institute’s strategy to fund multi-institutional, multidisciplinary consortia to design and conduct early phase clinical trials in patients with high grade gliomas. (2021) (0)
- Editorial: Tumor and antiepileptic drugs: clinical article. (2013) (0)
- EXTH-53. IN VIVO QUANTITATIVE ANALYSIS OF ONCOLYTIC VIRUS-TUMOR KINETICS (2018) (0)
- Magnetic resonance imaging of HSV-based in vivo transgene expression (2001) (0)
- Analysis of microRNA expression in glioblastoma invasion (2007) (0)
- Abstract B46: The long noncoding RNA INCA1 is a novel regulator of PD-L1 expression in tumors (2020) (0)
- 46. PAN-CANCER ANALYSIS OF ORTHOTOPIC PATIENT DERIVED XENOGRAFTS FROM BRAIN METASTASES (2020) (0)
- Extracellular Vesicles and MicroRNAs: Their Role in Tumorigenicity and Therapy for Brain Tumors (2016) (0)
- Cancer GeneTherapy Using aReplication- Competent Herpes Simplex Virus Type1Vector (1998) (0)
- Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial (2018) (0)
- 624. Effect of an Oncolytic HSV Mutant Expressing ICP34.5 under Control of a Nestin Promoter for Brain Tumor Therapy (2004) (0)
- IMMU-05. IMMUNE STIMULATION AND IMMUNE CHECKPOINT INHIBITION PROVIDED BY A SINGLE AGENT: AN ONCOLYTIC HSV EXPRESSING A scFv ANTIBODY AGAINST PD-1 (2017) (0)
- TGF b Treatment Enhances Glioblastoma Virotherapy by Inhibiting the Innate Immune Response (2015) (0)
- A new transcriptionally driven oncovirus with Vstat 120 expression has antiangiogenic and anti-tumorigenic effects (2010) (0)
- Editorial: functional neurooncology. (2012) (0)
- Editorial: glioblastoma and surgery. (2013) (0)
- Examination of the pathological mechanism of the microtubule associated protein tau using an HSV amplicon based neuronal gene delivery system (2003) (0)
- Cytomegalovirus Infection Leads to Pleomorphic Rhabdomyosarcomas in Trp53 þ / (cid:2) Mice (2012) (0)
- Involvement of GPR3 against apoptotic cell death during cerebellar development (2011) (0)
- Performing Quality Research in an Era of Reforms (2011) (0)
- CBIO-26. SUBPOPULATIONS OF CIRCULATING EXTRACELLULAR VESICLES OF GLIOBLASTOMA PATIENTS CAN BE DISTINGUISHED BY IMAGING FLOW CYTOMETRY (2017) (0)
- Introduction to the issue (2003) (0)
- Advances in Brief Comparative Analyses of Transgene Delivery and Expression in Tumors Inoculated with a Replication-conditional or-defective Viral Vector 1 (2001) (0)
- A focus on low-grade glioma INTRODUCTION (2015) (0)
- Replication conditional HSV-1 vector carrying CYP2B1 transgene combined with radiation cyclophosphamide and ganciclovir (2000) (0)
- AI-27BKM-120: AN ANTI-INVASIVE CANDIDATE FOR THE TREATMENT OF GLIOBLASTOMA (2014) (0)
- Abstract 3963: MicroRNA-124 and microRNA-1, commonly lost in glioma, coordinately target sphingosine kinase-1 in glioma cells (2011) (0)
- Abstract B167: Targeting glioblastoma invasion with GSK-3 inhibitors: Rapid effects on vimentin dynamics. (2013) (0)
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What Schools Are Affiliated With Ennio Antonio Chiocca?
Ennio Antonio Chiocca is affiliated with the following schools: