Ernest Briët

Ernest Briët's AcademicInfluence.com Rankings

Ernest Briët

Chemistry

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Chemistry

Ernest Briët's Degrees

PhD Pharmaceutical Sciences University of Amsterdam
Masters Pharmacy University of Groningen

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Ernest Briët's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

A Method to Determine the Optimal Intensity of Oral Anticoagulant Therapy (1993) (1958)
Venous thrombosis due to poor anticoagulant response to activated protein C: Leiden Thrombophilia Study (1993) (1366)
Role of clotting factor VIII in effect of von Willebrand factor on occurrence of deep-vein thrombosis (1995) (1167)
Increased risk of venous thrombosis in oral-contraceptive users who are carriers of factor V Leiden mutation (1994) (1125)
Thromboembolic and Bleeding Complications in Patients With Mechanical Heart Valve Prostheses (1994) (1008)
Optimal oral anticoagulant therapy in patients with mechanical heart valves. (1995) (944)
Increased fetal loss in women with heritable thrombophilia (1996) (670)
Bleeding complications in oral anticoagulant therapy. An analysis of risk factors. (1993) (590)
Pharmacological strategies to decrease excessive blood loss in cardiac surgery: a meta-analysis of clinically relevant endpoints (1999) (447)
Hereditary protein S deficiency: clinical manifestations. (1987) (414)
Protein C deficiency in a controlled series of unselected outpatients: an infrequent but clear risk factor for venous thrombosis (Leiden Thrombophilia Study) (1995) (388)
Increased risk of venous thrombosis in carriers of hereditary protein C deficiency defect (1993) (371)
Factor VII and Fibrinogen Levels as Risk Factors for Venous Thrombosis (1994) (326)
The Leiden Thrombophilia Study (LETS) (1997) (284)
A Prospective, Randomized Trial of Prednisone and Cyclophosphamide in the Treatment of Patients with Factor VIII Autoantibodies (1993) (268)
A sudden increase in factor VIII inhibitor development in multitransfused hemophilia A patients in The Netherlands. Dutch Hemophilia Study Group. (1993) (211)
Mortality and causes of death in Dutch haemophiliacs, 1973–86 (1989) (204)
Cardiovascular Determinants of Carotid Artery Disease: The Rotterdam Elderly Study (1992) (202)
Usefulness of patient interview in bleeding disorders. (1995) (191)
Assessment of a Bleeding Risk Index in Two Cohorts of Patients Treated with Oral Anticoagulants (1996) (187)
The spectrum of genetic defects in a panel of 40 Dutch families with symptomatic protein C deficiency type I: heterogeneity and founder effects. (1991) (149)
Dominant type 1 von Willebrand disease caused by mutated cysteine residues in the D3 domain of von Willebrand factor. (1996) (137)
Gene-gene and gene-environment interactions determine risk of thrombosis in families with inherited antithrombin deficiency. (1999) (133)
The role of donor antibodies in the pathogenesis of transfusion‐related acute lung injury: a systematic review (2008) (121)
Hereditary Protein S Deficiency and Venous Thrombo-Embolism (1985) (118)
Clinical predictors of alloimmunization after red blood cell transfusion (2007) (111)
Report of a joint WHO/WFH meeting on the control of haemophilia: carrier detection and prenatal diagnosis. (1993) (108)
Hereditary Protein S Deficiency in Young Adults with Arterial Occlusive Disease (1990) (101)
Expression of the blood-clotting factor-VIII cDNA is repressed by a transcriptional silencer located in its coding region. (1995) (94)
Toward Gene Therapy in Haemophilia A: Retrovirus-Mediated Transfer of a Factor VIII Gene into Murine Haematopoietic Progenitor Cells (1992) (85)
Modern haemophilia treatment: medical improvements and quality of life (1990) (84)
Optimal intensity of oral anticoagulant therapy after myocardial infarction. (1996) (83)
Multiple substitutions in the von Willebrand factor gene that mimic the pseudogene sequence. (1994) (80)
Expression of functional factor VIII in primary human skin fibroblasts after retrovirus-mediated gene transfer. (1990) (79)
Mortality in hereditary antithrombin-III deficiency—1830 to 1989 (1991) (78)
Successful treatment with recombinant factor VIIa of therapy‐resistant severe bleeding in a patient with acquired von Willebrand disease (2001) (77)
Toward gene therapy for hemophilia A: long-term persistence of factor VIII-secreting fibroblasts after transplantation into immunodeficient mice. (1993) (73)
The putative factor IX gene promoter in hemophilia B Leyden. (1988) (73)
Physical condition, longevity, and social performance of Dutch haemophiliacs, 1972-85. (1989) (70)
Fibrinopeptide A and beta thromboglobulin in patients with angina pectoris and acute myocardial infarction. (1984) (70)
Familial elevation of plasma histidine‐rich glycoprotein in a family with thrombophilia (1987) (68)
Bleeding complications in oral anticoagulant therapy : an analysis of risk factors (1993) (68)
Storage time of red blood cells and mortality of transfusion recipients. (2013) (63)
Carrier testing and prenatal diagnosis for hemophilia: experiences and attitudes of 549 potential and obligate carriers. (1990) (63)
Prevalence of leucocyte antibodies in the Dutch donor population (2011) (62)
Hemophilia treatment in historical perspective: a review of medical and social developments (1991) (62)
Mutations in Severe, Type III von Willebrand’s Disease in the Dutch Population: Candidate Missense and Nonsense Mutations Associated with Reduced Levels of von Willebrand Factor Messenger RNA (1992) (60)
Cerebral haemorrhagic infarction in young patients with hereditary protein C deficiency: evidence for "spontaneous" cerebral venous thrombosis. (1985) (60)
Elevated Plasminogen Activator Inhibitor (PAI), a Cause of Thrombophilia? – A Study in 203 Patients with Familial or Sporadic Venous Thrombophilia (1989) (59)
LOW-DOSE HEPARIN PROPHYLAXIS AGAINST DEEP-VEIN THROMBOSIS AFTER ACUTE STROKE (1978) (57)
Two novel point mutations correlate with an altered developmental expression of blood coagulation factor IX (hemophilia B Leyden phenotype). (1989) (56)
A congenitally abnormal fibrinogen (Vlissingen) with a 6-base deletion in the gamma-chain gene, causing defective calcium binding and impaired fibrin polymerization. (1991) (56)
Hemophilia B Leyden: a sex-linked hereditary disorder that improves after puberty. (1982) (56)
Well-being of haemophilia patients: a model for direct and indirect effects of medical parameters on the physical and psychosocial functioning. (1998) (54)
Female donors and transfusion‐related acute lung injury (2010) (52)
Bleeding time, blood groups and von Willebrand factor (1989) (52)
Storage time of blood products and transfusion‐related acute lung injury (2012) (46)
Hereditary Protein C-Deficiency: Laboratory Values in Transmitters and Guidelines for the Diagnostic Procedure Report on a Study of the SSC Subcommittee on Protein C and Protein S (1992) (46)
Carrier detection in hemophilia A: a cooperative international study. I. The carrier phenotype. (1986) (46)
THROMBOPHILIA:ITS CAUSES AND A ROUGH ESTIMATE OF ITS PREVALENCE (1987) (45)
A Monoclonal Antibody-Based Qunatitative Enzyme Immunoassay for the Determination of Plasma Fibrinogen Concentartions (1988) (44)
The Increasing Prevalence of Haemophilia (1990) (44)
High Titer Inhibitors in Severe Haemophilia A (1994) (41)
The human clotting factor VIII cDNA contains an autonomously replicating sequence consensus- and matrix attachment region-like sequence that binds a nuclear factor, represses heterologous gene expression, and mediates the transcriptional effects of sodium butyrate (1996) (40)
Carrier detection in hemophilia A: a cooperative international study. II. The efficacy of a universal discriminant. (1986) (38)
Two decades of haemophilia treatment in the Netherlands, 1972–92 (1995) (38)
A novel candidate mutation (Arg611→ His) in type I‘platelet discordant’von Willebrand's disease with desmopressin‐induced thrombocytopenia (1995) (37)
Molecular Variant of Factor VII (1976) (37)
Hereditary antithrombin deficiency: heterogeneity of the molecular basis and mortality in Dutch families. (1994) (37)
Mortality after transfusions, relation to donor sex (2011) (37)
A prospective survey of risk factors in young adults with arterial occlusive disease. (1989) (36)
Diagnostic value of fibrinopeptide A and beta-thromboglobulin in acute deep venous thrombosis and pulmonary embolism. (2009) (36)
Noonan syndrome: partial factor XI deficiency. (1988) (35)
Coagulation parameters of CPD fresh‐frozen plasma and CPD cryoprecipitate‐poor plasma after storage at 4°C for 28 days (1993) (34)
Fibrinogen Nijmegen : Congenital Dysfibrinogenemia Associated with Impaired t-PA Mediated Plasminogen Activation and Decreased Binding of t-PA (1988) (31)
Abnormal transbilayer mobility of phosphatidylcholine in hereditary pyropoikilocytosis reflects the increased heat sensitivity of the membrane skeleton. (1985) (31)
Evaluation of the Cuticle Bleeding Time in Canine Haemophilia A (1986) (31)
Mesenteric vein thrombosis as presenting manifestation of hereditary protein S deficiency. (1987) (31)
ACQUIRED VON WILLEBRAND'S DISEASE DUE TO EXCESSIVE FIBRINOLYSIS (1992) (30)
KLINEFELTER SYNDROME: PREDISPOSITION TO ACUTE NON-LYMPHOCYTIC LEUKÆMIA? (1980) (28)
The prophylactic treatment of hemophilia B Leyden with anabolic steroids. (1985) (28)
Genetic linkage of two intragenic restriction fragment length polymorphisms with von Willebrand's disease type IIA. Evidence for a defect in the von Willebrand factor gene. (1988) (28)
The Role of Factor VII in Haemostasis: Infusion Studies of Factor VIIa in a Canine Model of Factor VIII Deficiency (1990) (27)
Warfarin and aspirin after heart-valve replacement. (1994) (26)
Eleven novel mutations in the factor VIII gene from Brazilian hemophilia A patients. (1995) (26)
A Randomized and Blinded Comparison of Three Bleeding Time Techniques: the Ivy Method, and the Simplate II® Method in Two Directions (1992) (26)
A CRM‐Positive Variant of Factor‐VII Deficiency and the Detection of Heterozygotes with the Assay of Factor‐like Antigen (1977) (26)
Fibrinolytic System During Long-Distance Running in IDDM Patients and in Healthy Subjects (1992) (25)
Inhibitors in Christmas disease. (1984) (25)
Diurnal changes in heparin effect during continuous constant‐rate infusion. A study in nine patients with venous thromboembolism (1994) (24)
Diurnal Rhythm in Anticoagulant Effect of Heparin during a Low Dose Constant Rate Infusion (1992) (24)
AIDS and haemophilia. A study among Dutch haemophiliacs on the psychological impact of the AIDS threat, the prevalence of HIV antibodies and the adoption of measures to prevent HIV transmission. (1988) (24)
The role of splenectomy in the treatment of relapsing thrombotic thrombocytopenic purpura (1995) (24)
A polymorphic Xba I site within the human von Willebrand factor (vWF) gene identified by a vWF cDNA clone. (1986) (23)
Employment of individuals with haemophilia in The Netherlands. (1989) (22)
A Second Plasma Inhibitor of Activated Protein C: α1-Antitrypsin (1989) (21)
Coagulation parameters of CPD fresh-frozen plasma and CPD cryoprecipitate-poor plasma after storage at 4 degrees C for 28 days. (1993) (21)
Combined hereditary deficiency of the sixth component of complement and factor VIII coagulant activity in a Dutch family. (1982) (21)
Prolonged bleeding time due to mitotane therapy. (1991) (21)
KLINEFELTER SYNDROME: PREDISPOSITION TO ACUTE NON-LYMPHOCYTIC LEUKÆMIA? (1980) (20)
FAMILY HISTORY AND INHERITED THROMBOPHILIA (1995) (19)
Azathioprine and subacute myelomonocytic leukemia. (2009) (19)
Genotype Assignment of Haemophilia A by Use of Intragenic and Extragenic Restriction Fragment Length Polymorphisms (1987) (18)
Sex ratio of the mutation frequencies in haemophilia A: coagulation assays and RFLP analysis. (1991) (18)
State and Prospects of Gene Therapy for the Hemophilias (1995) (18)
Hip surgery in a patient with severe factor VII deficiency. (1987) (17)
Factor VIII preparations: need for prospective pharmacovigilance (1993) (17)
ORAL ANTICOAGULANT DRUGS. AUTHOR'S REPLIES (1992) (17)
Instability of repeats of the von Willebrand factor gene variable number tandem repeat sequence in intron 40 (1993) (17)
Oral contraception and the detection of carriers in haemophilia B. (1978) (17)
Paroxysmal Finger Haematoma: A Neglected Syndrome (1991) (16)
Somatic origin of inherited haemophilia A (1990) (16)
Rabbit Polyclonal Antibodies Against the Calcium-Dependent Conformation of Factor IX and Their Application in Solid Phase Immunoradiometric Assays (1986) (15)
Anticoagulant effect of unfractionated heparin in antithrombin-depleted plasma in vitro. (1996) (15)
Protein C (PC) and coumarin-induced skin necrosis (1986) (14)
Sex ratio of the mutation frequencies in haemophilia A: estimation and meta-analysis (1990) (14)
Inhibitors in hemophilia A: are some products safer? (1994) (13)
The Clinical Diagnosis Of Deep Venous Thrombosis (1981) (13)
PLASMA HISTIDINE-RICH GLYCOPROTEIN AND THROMBOPHILIA (1988) (13)
A second plasma inhibitor of activated protein C: alpha 1-antitrypsin. (1989) (12)
A one-year follow-up study of plasma fibrinopeptide A and beta-thromboglobulin after deep vein thrombosis and pulmonary embolism. (1982) (12)
Simplified procedure for the assay of fibrinopeptide A in plasma. (1981) (12)
The clinical benefit of blood transfusion: a hypothetical experiment based on a nationwide survey of severe maternal morbidity (2013) (12)
Peri-Operative Replacement Therapy with Factor VII Concentrate in a Patient with Severe Factor VII Deficiency (1992) (11)
Conservative management of placental abruption complicated by severe clotting disorders. (1992) (11)
Plasma beta-thromboglobulin and platelet factor 4 in renal failure. (1981) (11)
Carrier Detection of Haemophilia B by Using an Intragenic Restriction-Fragment Length Polymorphism (1985) (10)
Double Strand Conformation Polymorphism (DSCP) Detects Two Point Mutations at Codon 280 (AAC→ATC) and at Codon 431 (TAC→AAC) of the Blood Coagulation Factor VIII Gene (1993) (10)
First trimester prenatal diagnosis of haemophilia A: Two years' experience (1988) (10)
Alloexposed blood donors and transfusion‐related acute lung injury: a case‐referent study (2011) (10)
Regulation of blood coagulation and thrombosis. (1985) (10)
The contribution of DNA analysis to carrier detection and prenatal diagnosis of hemophilia A and B (2005) (9)
Microangiopathic haemolytic anaemia with advanced breast carcinoma: improvement with chemotherapy. (1985) (9)
THROMBOPHILIA AND HEREDITARY INCREASE IN PLASMINOGEN ACTIVATOR INHIBITOR (PAI-1 (1988) (8)
A solution to the problem of studying blood donor–related risk factors when patients have received multiple transfusions (2010) (8)
The inheritance and molecular genetics of von Willebrand's disease (1995) (8)
Two Mutations of the Factor IX Gene Including a Donor Splice Consensus Deletion and a Point Mutation in a Dutch Patient with Severe Hemophilia B (1990) (8)
Abnormal immune parameters in HIV‐seronegative haemophilic patients (1996) (8)
Inversions in the factor VIII gene: improvement of carrier detection and prenatal diagnosis in Dutch haemophilia A families. (1995) (8)
Interaction of factor V Leiden with inherited anti-thrombin deficiency (1995) (6)
Factor V Leiden mutation and contraception (1996) (6)
Sequential administration of human and porcine factor VIII for surgical treatment of a parotid tumour in a patient with a factor VIII inhibitor. (1985) (5)
Effects of Chronic Factor VIII Substitution on Immune Parameters in HIV Seronegative Haemophiliacs: a Comparison between Cryoprecipitate and Factor VIII Concentrate (1996) (5)
Value of the patient interview: all but consensus among haemostasis experts. (1992) (5)
A Dutch pedigree with mild hemophilia B with a missense mutation in the first EGF domain (factor IXOud en Nieuw Gastel). (1989) (5)
Seeming homozygosity in type-IIB von Willebrand's disease due to a polymorphism within the sequence of a commonly used primer (1994) (5)
Haemophilia B Leyden in Greece (1986) (5)
A Dutch family with moderately severe hemophilia B (factor IXHeerde) has a missense mutation identical to that of factor IX London 2. (1989) (5)
Monitoring heparin treatment with the APTT: the effect of methodological changes on the APTT. (1996) (5)
The optimal intensity of oral anticoagulation therapy in patients with prosthetic heart valves (1992) (4)
The clinical diagnosis of deep venous thrombosis. A study of ambulant patients in The Netherlands using Doppler ultrasonography and phlebography. (1983) (4)
Hereditary Diseases and Blood Transfusion (1995) (4)
The incidence of inhibitors in hemophilia A and the induction of immune tolerance. (2001) (4)
Chronic lymphocytic leukaemia and IgG heavy chain disease. (2009) (4)
Preparation of lyophilized heat-treated cryoprecipitates from a small pool of plasma obtained by apheresis (1991) (4)
More objective diagnoses of venous thromboembolism? (1991) (3)
[Revision consensus hemophilia: treatment and responsibility. Nederlandse Vereniging van Hemophilia Patients]. (1997) (3)
Plasma Fibrinopeptide A and Beta-Thromboglobulin in Major Bacterial Infections (1982) (3)
[Pharmacotherapeutic choices for correction of disorders of primary hemostasis]. (1999) (3)
Three problems of hemophilia B : a study of abnormal factor IX molecules with an inhibitor neutralization assay (1977) (2)
[Blind spots of the diagnostic hemostasis screen]. (2000) (2)
A Study in Three Dutch Families (2018) (2)
[Physical diagnosis--percussion and palpation of the spleen]. (2000) (2)
[Consensus diagnosis pulmonary embolism]. (1993) (2)
221 Impaired stimulation of t-PA mediated plasminogen activation and decreased binding of t-PA in a congenital dysfibrinogenemia (1988) (2)
[Recombinant factor VIIa (eptacog alfa): a new therapeutic option for patients with severe bleeding disorder due to inhibitory antibodies against a coagulation factor]. (1998) (2)
Variants of Vitamin K Dependent Coagulation Factors (1979) (2)
[Consensus hemophilia treatment]. (1987) (2)
Partial Reconstitution of Factor VIII Activity from a Mild Crm+ Hemophilia A Patient by Replacement of the Defective A2 Domain (1998) (2)
[Prevention of central nervous system hemorrhages in patients with hemophilia]. (1992) (1)
Thyroxine supplementation in very preterm infants (1998) (1)
THE ORIGIN OF THE MUTATION IN FAMILIES WITH AN ISOLATED CASE OF HAEMOPHILIA A (1987) (1)
[The causes of venous thrombosis and lung embolism]. (1985) (1)
Quality control programme for the preparation of small-pool lyophilized heat-treated cryoprecipitates (1991) (1)
[Detection of carrier state of hemophilia; current status]. (1984) (1)
Low-dose subcutaneous heparin for prevention of deep vein thrombosis in non-surgical patients. (1985) (1)
Allo‐exposure status and leucocyte antibody positivity of blood donors show a similar relation with TRALI (2012) (1)
Tolerance and intolerance to factor VIII: a clinical perspective. (1995) (1)
Carrier Detection in Hemophilia B. (1977) (1)
Fibrinopeptide A And Beta-Thromboglobulin Concentrations In Venous And Arterial Disorders (1981) (1)
TWO VON WILLEBRAND FACTOR (vWF) GENE POLYMORPHISMS SEGREGATE WITH VON WILLEBRAND'S DISEASE (vWD) TYPE IIA: ASSIGNMENT OF THE DEFECTIVE GENE LOCUS IN vWD TYPE IIA (1987) (1)
Abnormal fibrins defective in the exposure of sites involved in the acceleration of t-PA mediated plasminogen activation (1994) (1)
Thrombosis, anticoagulation and bleeding: About age and other risk factors (1992) (0)
[Search for the carrier state of hemophilia B using restriction fragment length polymorphism]. (1985) (0)
A 72-year-old woman with fever and diffuse intravascular coagulation (1992) (0)
Coagulum pyelolithotomy: the determination of optimal conditions for clot formation (1986) (0)
Toward Gene Therapy in Hemophilia A: Introduction of Factor VIII Expression Vectors Into Somatic Cells (1990) (0)
L.E.T.S.: Leiden thrombophilia study; interim analysis (1992) (0)
[Oral contraception increases the chance of venous thrombosis in factor V Leiden mutation]. (1995) (0)
Oral anticoagulant drugs. (1992) (0)
[HIV infection in hemophilia patients; report from the National Ombudsman]. (1995) (0)
X-Linked Coagulation Disorders (1984) (0)
IMMUNOLOGICAL ASSAYS FOR THE Ca(II)-DEPENDENT AND NONCa(II)-DEPENDENT CONFORMATIONS OFJtLUMAN PROTELN Z (PZ) (1987) (0)
[Epidemiology of AIDS and HIV infections in the Netherlands; current status and prognosis for 1987-1990]. (1987) (0)
Hereditary protein C deficiency in symptomatic families: Individuals with the genetic defect have an increased risk for venous thrombotic events (1992) (0)
[Positive effect of long-term coumarin treatment following a heart infarct]. (1994) (0)
[Social effects of current hemophilia treatment]. (1989) (0)
Circadian changes in heparin sensitivity (1990) (0)
Thrombosis in Families With Inherited Antithrombin Deficiency Gene-Gene and Gene-Environment Interactions Determine Risk of (2013) (0)
[Doubts about the new oral anticoagulants]. (2014) (0)
[Hemorrhagic diathesis in Noonan syndrome]. (1987) (0)
[Abruptio placentae and coagulation disorders]. (1991) (0)
O764 THE CLINICAL BENEFIT OF BLOOD TRANSFUSION; A HYPOTHETICAL EXPERIMENT BASED ON A NATIONWIDE SURVEY OF SEVERE MATERNAL MORBIDITY (2012) (0)
No Malabsorption of Inorganic Ferrous Iron in Patients with Achylia gastrica (1979) (0)
Inversions inthefactor VIIIgene: improvement ofcarrier detection andprenatal diagnosis in Dutchhaemophilia A families (1995) (0)
Use of Gene Probes for Carrier Detection and Prenatal Diagnosis in Hemophilia A (1988) (0)
A Molecular Variant of Factor VII. Correction (1977) (0)
Renal embolisation in Glanzmann's thrombasthenia. (1980) (0)
Lover's arm (1992) (0)
Research and development (2010) (0)
In Vitro Determination of Optimal Conditions for Coagulum Pyelolithotomy (1985) (0)
Thrombosis-related death in families with inherited antithrombin deficiency (1996) (0)
phenotype) expression of blood coagulation factor IX (hemophilia B Leyden Two novel point mutations correlate with an altered developmental (2011) (0)
[An unusual cause of hemorrhagic diathesis]. (1981) (0)
THE BENEFITS OF MODERN SUBSTITUTION THERAPY IN HEMOPHILIA (1987) (0)
The Molecular Defect Of Factor IX Chapel Hill (1981) (0)
Royal academy of medicine in Ireland international conference on homocysteine metabolism from basic science to clinical medicine (1995) (0)
Heparin treatment: confusion still prevails. (1989) (0)
[Are there still indications for plasma transfusions?]. (1991) (0)
[The yet unexpected vitamin K deficiency]. (1986) (0)
Hereditary diseases and blood transfusion : proceedings of the Nineteenth International Symposium on Blood Transfusion, Groningen, 1994 (1995) (0)
ALLO-EXPOSED BLOOD DONORS AND TRANSFUSION-RELATED ACUTE LUNG INJURY (2010) (0)

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What Schools Are Affiliated With Ernest Briët?

Ernest Briët is affiliated with the following schools:

Leiden University