Ed. Dewey W. Hall
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(Suggest an Edit or Addition)Ed. Dewey W. Hall's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Benefit of vitamin E, riluzole, and gababapentin in a transgenic model of familial amyotrophic lateral sclerosis (1996) (675)
- Central nervous system trauma and stroke. I. Biochemical considerations for oxygen radical formation and lipid peroxidation. (1989) (646)
- Gender differences in acute CNS trauma and stroke: neuroprotective effects of estrogen and progesterone. (2000) (624)
- Central nervous system trauma and stroke. II. Physiological and pharmacological evidence for involvement of oxygen radicals and lipid peroxidation. (1989) (577)
- The neuroprotective pharmacology of methylprednisolone. (1992) (472)
- Relationship of microglial and astrocytic activation to disease onset and progression in a transgenic model of familial ALS (1998) (431)
- Antioxidant therapies for traumatic brain injury (2011) (377)
- Antioxidant therapies in traumatic brain and spinal cord injury. (2012) (375)
- Relationship of microglial and astrocytic activation to disease onset and progression in a transgenic model of familial ALS. (1998) (351)
- Time Course of Post-Traumatic Mitochondrial Oxidative Damage and Dysfunction in a Mouse Model of Focal Traumatic Brain Injury: Implications for Neuroprotective Therapy (2006) (313)
- Protein Oxidative Damage in a Transgenic Mouse Model of Familial Amyotrophic Lateral Sclerosis (1998) (297)
- Spatial and temporal characteristics of neurodegeneration after controlled cortical impact in mice: more than a focal brain injury. (2005) (292)
- Effects of the 21-aminosteroid U74006F on experimental head injury in mice. (1988) (281)
- 21-Aminosteroid lipid peroxidation inhibitor U74006F protects against cerebral ischemia in gerbils. (1988) (266)
- Digital Commons@Becker Digital Commons@Becker Classification of traumatic brain injury for targeted therapies Classification of traumatic brain injury for targeted therapies Classification of Traumatic Brain Injury for Targeted Therapies (2008) (259)
- Sex Differences in Postischemic Neuronal Necrosis in Gerbils (1991) (256)
- Pathophysiology of spinal cord trauma. (1993) (252)
- Effects of intravenous methylprednisolone on spinal cord lipid peroxidation and Na+ + K+)-ATPase activity. Dose-response analysis during 1st hour after contusion injury in the cat. (1982) (244)
- Neuroprotection and acute spinal cord injury: A reappraisal (2011) (243)
- Free radicals in CNS injury. (1993) (238)
- Glucocorticoid mechanisms in acute spinal cord injury: a review and therapeutic rationale. (1982) (234)
- Peroxynitrite-mediated protein nitration and lipid peroxidation in a mouse model of traumatic brain injury. (2004) (229)
- A pharmacological analysis of the pathophysiological mechanisms of posttraumatic spinal cord ischemia. (1986) (228)
- Brain Hydroxyl Radical Generation in Acute Experimental Head Injury (1993) (228)
- High-dose glucocorticoid treatment improves neurological recovery in head-injured mice. (1985) (216)
- Clinical trials in head injury. (1999) (211)
- Therapeutic potential of the lazaroids (21-aminosteroids) in acute central nervous system trauma, ischemia and subarachnoid hemorrhage. (1994) (211)
- Direct measurement of hydroxyl radicals, lipid peroxidation, and blood-brain barrier disruption following unilateral cortical impact head injury in the rat. (1994) (204)
- Mild pre- and posttraumatic hypothermia attenuates blood-brain barrier damage following controlled cortical impact injury in the rat. (1996) (202)
- Effects of multi-dose methylprednisolone sodium succinate administration on injured cat spinal cord neurofilament degradation and energy metabolism. (1984) (202)
- Estrogen-related gender difference in survival rate and cortical blood flow after impact-acceleration head injury in rats. (2000) (202)
- Lipid hydrolysis and peroxidation in injured spinal cord: partial protection with methylprednisolone or vitamin E and selenium. (1985) (200)
- Correlation of methylprednisolone levels in cat spinal cord with its effects on (Na+ + K+)-ATPase, lipid peroxidation, and alpha motor neuron function. (1982) (199)
- Role of peroxynitrite in secondary oxidative damage after spinal cord injury (2007) (197)
- Evolution of post-traumatic neurodegeneration after controlled cortical impact traumatic brain injury in mice and rats as assessed by the de Olmos silver and fluorojade staining methods. (2008) (195)
- Biochemistry and pharmacology of lipid antioxidants in acute brain and spinal cord injury. (1992) (194)
- Relationship of oxygen radical‐induced lipid peroxidative damage to disease onset and progression in a transgenic model of familial ALS (1998) (193)
- Evaluation of an intensive methylprednisolone sodium succinate dosing regimen in experimental spinal cord injury. (1987) (192)
- Effects of a single large dose of methylprednisolone sodium succinate on experimental posttraumatic spinal cord ischemia. Dose-response and time-action analysis. (1984) (188)
- Riluzole preserves motor function in a transgenic model of familial amyotrophic lateral sclerosis (1998) (175)
- Effects of the 21-aminosteroid U74006F on posttraumatic spinal cord ischemia in cats. (1988) (168)
- Treatment of mice with methamphetamine produces cell loss in the substantia nigra (1996) (166)
- Antioxidant Therapies for Acute Spinal Cord Injury (2011) (163)
- Importance of pharmacologic considerations in the evaluation of new treatments for acute spinal cord injury. (1992) (162)
- Lactate and pyruvate metabolism in injured cat spinal cord before and after a single large intravenous dose of methylprednisolone. (1983) (148)
- U-78517F: a potent inhibitor of lipid peroxidation with activity in experimental brain injury and ischemia. (1991) (146)
- Effects of treatment with U-74006F on neurological outcome following experimental spinal cord injury. (1988) (145)
- A Comparison of Long-Term Functional Outcome After 2 Middle Cerebral Artery Occlusion Models in Rats (2001) (144)
- Lipid antioxidants in acute central nervous system injury. (1993) (143)
- Dextran-coupled deferoxamine improves outcome in a murine model of head injury. (1992) (142)
- A new 21-aminosteroid antioxidant lacking glucocorticoid activity stimulates adrenocorticotropin secretion and blocks arachidonic acid release from mouse pituitary tumor (AtT-20) cells. (1988) (139)
- Role of lipid peroxidation in post-traumatic spinal cord degeneration: a review. (1986) (139)
- Hydroxyl radical production and lipid peroxidation paralles selective post‐ischemic vulnerability in gerbil brain (1993) (139)
- Neuroprotective effects of the dopamine D2/D3 agonist pramipexole against postischemic or methamphetamine-induced degeneration of nigrostriatal neurons (1996) (139)
- Temporal relationship of peroxynitrite-induced oxidative damage, calpain-mediated cytoskeletal degradation and neurodegeneration after traumatic brain injury (2007) (138)
- Current application of "high-dose" steroid therapy for CNS injury. A pharmacological perspective. (1985) (137)
- Peroxynitrite‐mediated oxidative damage to brain mitochondria: Protective effects of peroxynitrite scavengers (2007) (136)
- Attenuation of postischemic cerebral hypoperfusion by the 21-aminosteroid U74006F. (1988) (133)
- Acute effects of intravenous glucocorticoid pretreatment on the in vitro peroxidation of cat spinal cord tissue (1981) (131)
- Neuroprotective Effects of Tempol, a Catalytic Scavenger of Peroxynitrite-Derived Free Radicals, in a Mouse Traumatic Brain Injury Model (2008) (130)
- The 21-aminosteroids: Potent inhibitors of lipid peroxidation for the treatment of central nervous system trauma and ischemia (1989) (129)
- Post-Injury Administration of Mitochondrial Uncouplers Increases Tissue Sparing and Improves Behavioral Outcome following Traumatic Brain Injury in Rodents. (2007) (127)
- Mitochondrial Uncoupling as a Therapeutic Target Following Neuronal Injury (2004) (127)
- Inhibition of lipid peroxidation in central nervous system trauma and ischemia (1995) (118)
- Selective death of newborn neurons in hippocampal dentate gyrus following moderate experimental traumatic brain injury (2008) (117)
- Comparative Neuroprotective Effects of Cyclosporin a and NIM811, a Nonimmunosuppressive Cyclosporin a Analog, following Traumatic Brain Injury (2009) (116)
- Correlation between attenuation of posttraumatic spinal cord ischemia and preservation of tissue vitamin E by the 21-aminosteroid U74006F: evidence for an in vivo antioxidant mechanism. (1989) (115)
- Mitochondrial protection after traumatic brain injury by scavenging lipid peroxyl radicals (2010) (115)
- Increased Amyloid Protein Precursor and Apolipoprotein E Immunoreactivity in the Selectively Vulnerable Hippocampus Following Transient Forebrain Ischemia in Gerbils (1995) (114)
- The novel calpain inhibitor SJA6017 improves functional outcome after delayed administration in a mouse model of diffuse brain injury. (2001) (113)
- Cytoskeletal protein degradation and neurodegeneration evolves differently in males and females following experimental head injury (2003) (107)
- Attenuation of acute mitochondrial dysfunction after traumatic brain injury in mice by NIM811, a non-immunosuppressive cyclosporin A analog (2008) (107)
- Glucocorticoid effects on central nervous excitability and synaptic transmission. (1982) (104)
- Ovariectomy exacerbates and estrogen replacement attenuates photothrombotic focal ischemic brain injury in rats. (2000) (103)
- Neuroprotective actions of glucocorticoid and nonglucocorticoid steroids in acute neuronal injury (1993) (100)
- Age‐Related Regional Changes in Hydroxyl Radical Stress and Antioxidants in Gerbil Brain (1993) (97)
- Effect of the aminosteroid U74006F after cardiopulmonary arrest in dogs. (1988) (97)
- Neuroprotection and acute spinal cord injury: A reappraisal (2004) (96)
- A nonglucocorticoid steroid analog of methylprednisolone duplicates its high-dose pharmacology in models of central nervous system trauma and neuronal membrane damage. (1987) (95)
- 4-Hydroxy-2,2,6,6-tetramethylpiperidine-1-oxyl (Tempol) inhibits peroxynitrite-mediated phenol nitration. (2000) (93)
- Therapeutic window analysis of the neuroprotective effects of cyclosporine A after traumatic brain injury. (2011) (93)
- Lipid peroxidation in brain or spinal cord mitochondria after injury (2016) (91)
- Relationship of calpain-mediated proteolysis to the expression of axonal and synaptic plasticity markers following traumatic brain injury in mice (2006) (88)
- Pathobiology of dynorphins in trauma and disease. (2005) (86)
- Novel inhibitors of iron‐dependent lipid peroxidation for neurodegenerative disorders (1992) (85)
- Effects of tirilazad mesylate on postischemic brain lipid peroxidation and recovery of extracellular calcium in gerbils. (1991) (84)
- The use of salicylate hydroxylation to detect hydroxyl radical generation in ischemic and traumatic brain injury. Reversal by tirilazad mesylate (U-74006F). (1993) (83)
- Administration of the Nrf2-ARE activators sulforaphane and carnosic acid attenuates 4-hydroxy-2-nonenal-induced mitochondrial dysfunction ex vivo. (2013) (82)
- Free radicals and CNS injury. (1989) (81)
- The role of oxygen radicals in traumatic injury: clinical implications. (1993) (80)
- Inhibition of arachidonic acid-induced vasogenic brain edema by the non-glucocorticoid 21-aminosteroid U74006F (1988) (80)
- Novel 21-aminosteroids that inhibit iron-dependent lipid peroxidation and protect against central nervous system trauma. (1990) (80)
- Lack of a gender difference in post-traumatic neurodegeneration in the mouse controlled cortical impact injury model. (2005) (79)
- Lipid peroxidation-derived reactive aldehydes directly and differentially impair spinal cord and brain mitochondrial function. (2010) (79)
- Nrf2–ARE activator carnosic acid decreases mitochondrial dysfunction, oxidative damage and neuronal cytoskeletal degradation following traumatic brain injury in mice (2015) (77)
- Involvement of lipid peroxidation in CNS injury. (1992) (77)
- Beneficial effects of the κ opioid receptor agonist U-50488H in experimental acute brain and spinal cord injury (1987) (75)
- Protective effects of tirilazad mesylate and metabolite U-89678 against blood-brain barrier damage after subarachnoid hemorrhage and lipid peroxidative neuronal injury. (1996) (73)
- Tirilazad Mesylate Protects Vitamins C and E in Brain Ischemia‐Reperfusion Injury (1992) (73)
- Dose-response analysis of the effect of 21-aminosteroid tirilazad mesylate (U-74006F) upon neurological outcome and ischemic brain damage in permanent focal cerebral ischemia (1994) (71)
- U-54494A: a unique anticonvulsant related to kappa opioid agonists. (1987) (71)
- Pyrrolopyrimidines: novel brain-penetrating antioxidants with neuroprotective activity in brain injury and ischemia models. (1997) (67)
- Infant rat model of the shaken baby syndrome: preliminary characterization and evidence for the role of free radicals in cortical hemorrhaging and progressive neuronal degeneration. (1998) (66)
- Quantitative analysis of effects of kappa-opioid agonists on postischemic hippocampal CA1 neuronal necrosis in gerbils. (1988) (66)
- Phenelzine Mitochondrial Functional Preservation and Neuroprotection after Traumatic Brain Injury Related to Scavenging of the Lipid Peroxidation-Derived Aldehyde 4-Hydroxy-2-Nonenal (2013) (66)
- Peroxynitrite Scavengers for the Acute Treatment of Traumatic Brain Injury (1999) (65)
- Pharmacological evidence for a role of peroxynitrite in the pathophysiology of spinal cord injury (2009) (65)
- Antioxidant effects in brain and spinal cord injury. (1992) (64)
- Special Article Pharmacological Treatment Of Acute Spinal Cord Injury: How Do We Build On Past Success? (2001) (64)
- Traumatic brain injury research priorities: the Conemaugh International Brain Injury Symposium. (2008) (64)
- Temporal and spatial dynamics of peroxynitrite-induced oxidative damage after spinal cord contusion injury. (2009) (63)
- Recommended guidelines for studies of human subjects with spinal cord injury (2005) (62)
- Neuroprotective effects of the dopamine agonists pramipexole and bromocriptine in 3-acetylpyridine-treated rats (1997) (62)
- Neuroprotective efficacy of microvascularly-localized versus brain-penetrating antioxidants. (1996) (61)
- Pharmacological inhibition of lipid peroxidation attenuates calpain‐mediated cytoskeletal degradation after traumatic brain injury (2011) (61)
- LC-MS/MS detection of peroxynitrite-derived 3-nitrotyrosine in rat microvessels. (2000) (60)
- Time courses of post-injury mitochondrial oxidative damage and respiratory dysfunction and neuronal cytoskeletal degradation in a rat model of focal traumatic brain injury (2017) (58)
- Generation and Detection of Hydroxyl Radical Following Experimental Head Injury (1994) (57)
- Relationship of nitric oxide synthase induction to peroxynitrite-mediated oxidative damage during the first week after experimental traumatic brain injury (2012) (55)
- Lipid peroxidation and the role of oxygen radicals in CNS injury. (1987) (55)
- Pre-Clinical Testing of Therapies for Traumatic Brain Injury. (2018) (55)
- Effect of delayed administration of U74006F (tirilazad mesylate) on recovery of locomotor function after experimental spinal cord injury. (1991) (54)
- Effects of the nonglucocorticoid 21-aminosteroid U74006F on acute cerebral hypoperfusion following experimental subarachnoid hemorrhage (1988) (54)
- Uptake and elimination of methylprednisolone from contused cat spinal cord following intravenous injection of the sodium succinate ester. (1983) (53)
- Acute enhancement of spinal cord synaptosomal (Na+ + K+)-ATPase activity in cats following intravenous methylprednisolone (1981) (51)
- New pharmacological treatment of acute spinal cord trauma. (1988) (48)
- Tempol protection of spinal cord mitochondria from peroxynitrite-induced oxidative damage (2009) (47)
- Inhibition of lipid peroxidation in CNS trauma. (1991) (45)
- Methylprednisolone for the Treatment of Patients with Acute Spinal Cord Injuries: A Propensity Score-Matched Cohort Study from a Canadian Multi-Center Spinal Cord Injury Registry. (2016) (45)
- Pathogenic mechanisms in familial amyotrophic lateral sclerosis due to mutation of Cu, Zn superoxide dismutase. (1996) (44)
- Synthesis of novel 2,4-diaminopyrrolo-[2,3-d]pyrimidines with antioxidant, neuroprotective, and antiasthma activity. (1995) (44)
- Effects of a 21-aminosteroid (U-74006F) on cerebral metabolites and edema after severe experimental head trauma. (1990) (44)
- A pharmacological analysis of the neuroprotective efficacy of the brain- and cell-permeable calpain inhibitor MDL-28170 in the mouse controlled cortical impact traumatic brain injury model. (2010) (44)
- Newer pharmacological approaches for antioxidant neuroprotection in traumatic brain injury (2019) (43)
- Temporal and spatial dynamics of nrf2-antioxidant response elements mediated gene targets in cortex and hippocampus after controlled cortical impact traumatic brain injury in mice. (2014) (43)
- Translational spinal cord injury research: preclinical guidelines and challenges. (2012) (42)
- Chronic traumatic encephalopathy-integration of canonical traumatic brain injury secondary injury mechanisms with tau pathology (2017) (41)
- Nonsteroidal lazaroid U78517F in models of focal and global ischemia. (1990) (41)
- Lack of effect of postinjury treatment with methylprednisolone or tirilazad mesylate on the increase in eicosanoid levels in the acutely injured cat spinal cord. (1995) (39)
- Intensive anti-oxidant pretreatment retards motor nerve degeneration (1987) (38)
- Cerebral ischaemia, free radicals and antioxidant protection. (1993) (36)
- Time course of production of hydroxyl free radical after subarachnoid hemorrhage in dogs. (2004) (35)
- Neuroimmunophilin Ligand V-10,367 is Neuroprotective after 24-Hour Delayed Administration in a Mouse Model of Diffuse Traumatic Brain Injury (2002) (35)
- HPLC-chemiluminescence and thermospray LC/MS study of hydroperoxides generated from phosphatidylcholine. (1995) (35)
- Synaptic Mitochondria are More Susceptible to Traumatic Brain Injury-induced Oxidative Damage and Respiratory Dysfunction than Non-synaptic Mitochondria (2018) (34)
- Neuroprotective effects of the novel brain‐penetrating pyrrolopyrimidine antioxidants U‐101033E and U‐104067F against post‐ischemic degeneration of nigrostriatal neurons (1997) (34)
- Attenuation of hemorrhagic shock by the non-glucocorticoid 21-aminosteroid U74006F. (1988) (34)
- Glucocorticoid preservation of motor nerve function during early degeneration (1977) (33)
- Protective Efficacy of a Hypothermic Pharmacological Agent in Gerbil Forebrain Ischemia (1993) (33)
- Acute effects of intravenous glucocorticoid on cat spinal motor neuron electrical properties (1982) (33)
- Pharmacological analysis of the cortical neuronal cytoskeletal protective efficacy of the calpain inhibitor SNJ‐1945 in a mouse traumatic brain injury model (2013) (32)
- Neuroprotective Efficacy and Mechanisms of Novel Pyrrolopyrimidine Lipid Peroxidation Inhibitors in the Gerbil Forebrain Ischemia Model (1998) (32)
- Steroids and neuronal destruction or stabilization. (1990) (32)
- Brain attack. Acute therapeutic interventions. Free radical scavengers and antioxidants. (1997) (32)
- Induction of apolipoprotein E mRNA in the hippocampus of the gerbil after transient global ischemia. (1996) (32)
- Identification and characterization of PEBP as a calpain substrate (2006) (32)
- Multifaceted roles of sphingosine‐1‐phosphate: How does this bioactive sphingolipid fit with acute neurological injury? (2008) (32)
- Effects of a single methylprednisolone dose on a facilitatory response of mammalian motor nerve. (1977) (31)
- The effects of chronic two-fold dietary vitamin E supplementation on subarachnoid hemorrhage-induced brain hypoperfusion (1987) (31)
- Inhibition of lipid peroxidation attenuates axotomy‐induced apoptotic degeneration of facial motor neurons in neonatal rats (1996) (30)
- Immunocytochemical method for investigating in vivo neuronal oxygen radical-induced lipid peroxidation (1997) (30)
- Effects of a Single Intravenous Glucocorticoid Dose on Biogenic Amine Levels in Cat Lumbar Spinal Cord (1982) (30)
- Attenuation of progressive brain hypoperfusion following experimental subarachnoid hemorrhage by large intravenous doses of methylprednisolone (1988) (29)
- Beneficial effects of acute intravenous ibuprofen on neurologic recovery of head-injured mice: comparison of cyclooxygenase inhibition with inhibition of thromboxane A2 synthetase or 5-lipoxygenase. (1985) (29)
- Mutant CuZn superoxide dismutase in motor neuron disease (1998) (29)
- Age-related phospholipid hydroperoxide levels in gerbil brain measured by HPLC-chemiluminescence and their relation to hydroxyl radical stress (1994) (29)
- Direct Measurement of Lipid Hydroperoxides in Iron‐Dependent Spinal Neuronal Injury (1996) (28)
- Glucocorticoid effects on spinal cord function. (1978) (28)
- Glucocorticoid effects on the electrical properties of spinal motor neurons (1982) (28)
- Role of animal studies in the design of clinical trials. (2009) (27)
- 2-(Aminomethyl)chromans that inhibit iron-dependent lipid peroxidation and protect against central nervous system trauma and ischemia. (1992) (27)
- Tirilazad widens the therapeutic window for riluzole-induced attenuation of progressive cortical degeneration in an infant rat model of the shaken baby syndrome. (1998) (27)
- Acute effects of methylprednisolone sodium succinate on spinal reflexes (1979) (27)
- Efficacy and mechanisms of action of the cytoprotective lipid peroxidation inhibitor tirilazad mesylate in subarachnoid haemorrhage. (1996) (26)
- Synaptic Mitochondria Sustain More Damage than Non-Synaptic Mitochondria after Traumatic Brain Injury and Are Protected by Cyclosporine A. (2017) (25)
- The 21-aminosteroid antioxidant tirilazad mesylate, U-74006F, blocks cortical hypoperfusion following spreading depression (1991) (24)
- Comparison of the efficacy of mechanistically different antioxidants in the rat hemorrhagic shock model. (1991) (23)
- Measurement of Oxygen Radicals and Lipid Peroxidation in Neural Tissues (2009) (23)
- Neuroprotective Properties of the Benzodiazepine Receptor, Partial Agonist PNU-101017 in the Gerbil Forebrain Ischemia Model (1997) (22)
- Role of oxygen radicals in stroke: effects of the 21-aminosteroids (lazaroids). A novel class of antioxidants. (1990) (22)
- Post-traumatic spinal cord ischemia: relationship to injury severity and physiological parameters. (1987) (22)
- Amelioration of impaired cerebral metabolism after severe acidotic ischemia by tirilazad posttreatment in dogs. (1996) (22)
- Methylprednisolone preservation of motor nerve function during early degeneration (1984) (22)
- The effects of glucocorticoid and nonglucocorticoid steroids on acute neuronal degeneration. (1993) (22)
- Effects of methylprednisolone and 21-aminosteroids on mitogen-induced interleukin-6 and tumor necrosis factor-alpha production in human peripheral blood mononuclear cells. (1995) (21)
- Lazaroids: Mechanisms of Action and Implications for Disorders of the CNS (1997) (21)
- A new class of compounds for stroke and trauma: effects of 21-aminosteroids on lipid peroxidation. (1987) (21)
- Continuous Infusion of Phenelzine, Cyclosporine A, or Their Combination: Evaluation of Mitochondrial Bioenergetics, Oxidative Damage, and Cytoskeletal Degradation following Severe Controlled Cortical Impact Traumatic Brain Injury in Rats. (2018) (20)
- Drug development in spinal cord injury: what is the FDA looking for? (2003) (20)
- Role of oxygen-derived free radicals in the pathogenesis of shock and trauma, with focus on central nervous system injuries. (1992) (20)
- Chapter 8 – Free radicals in central nervous system injury (1994) (20)
- Preservation of motor nerve function during early degeneration by the 21-aminosteroid anti-oxidant U74006F (1990) (20)
- Beneficial action of glucocorticoid treatment on neuromuscular transmission during early motor nerve degeneration (1983) (19)
- Comparative neuroprotective properties of the benzodiazepine receptor full agonist diazepam and the partial agonist PNU-101017 in the gerbil forebrain ischemia model (1998) (18)
- Antioxidant action of lazaroids. (1994) (18)
- "High-dose" methylprednisolone and CNS injury. (1986) (18)
- Phenelzine Protects Brain Mitochondrial Function In Vitro and In Vivo following Traumatic Brain Injury by Scavenging the Reactive Carbonyls 4-Hydroxynonenal and Acrolein Leading to Cortical Histological Neuroprotection. (2017) (18)
- Effects of the lipid peroxidation inhibitor tirilazed mesylate (U-74006F) on gerbil brain eicosanoid levels following ischemia and reperfusion (1994) (18)
- Acute Cardiovascular Response to a Single Large Intravenous Dose of Methylprednisolone and Its Effects on the Responses to Norepinephrine and Isoproterenol (1983) (17)
- Pharmacokinetics of methylprednisolone in cat plasma and spinal cord following a single intravenous dose of the sodium succinate ester. (1982) (17)
- Glucocorticoid effects on the edrophonium responsiveness of normal and degenerating mammalian motor nerve terminals (1977) (16)
- Is it time to resurrect “lazaroids”? (2017) (15)
- Lipid peroxidation. Discussion (1996) (15)
- Cardiovascular depressant effects of the kappa opioid receptor agonists U50488H and spiradoline mesylate. (1988) (15)
- Acute Therapeutic Interventions (1997) (14)
- The 21-aminosteroid U74006F reduces systemic lipid peroxidation, improves neurologic function, and reduces mortality after cardiopulmonary arrest in dogs. (1989) (14)
- Measurement of Oxygen Radicals and Lipid Peroxidation in Neural Tissues (2000) (14)
- Further studies of glucocorticoid effects on spinal cord function: single and repetitive monosynaptic transmission and apparent Ia afferent transmitter turnover. (1979) (14)
- Azulenyl nitrones: colorimetric detection of oxyradical end products and neuroprotection in the gerbil transient forebrain ischemia/reperfusion model. (1998) (14)
- Therapeutic value of 21-aminosteroid U74389F in acute spinal cord injury. (1993) (14)
- Tirilazad Prevention of Reperfusion Edema After Focal Ischemia in Cynomolgus Monkeys (1996) (13)
- Post-Injury Treatment with NIM811 Promotes Recovery of Function in Adult Female Rats after Spinal Cord Contusion: A Dose-Response Study. (2018) (13)
- Beneficial effects of the kappa opioid receptor agonist U-50488H in experimental acute brain and spinal cord injury. (1987) (12)
- Determination of methylprednisolone in central nervous tissue and plasma using normal-phase high-performance liquid chromatography. (1982) (12)
- U74389G prevents vasospasm after subarachnoid hemorrhage in dogs. (1998) (12)
- Direct effects of glucocorticoids on neuromuscular function. (1983) (11)
- Role of Oxygen Radicals in Central Nervous System Trauma (1993) (11)
- Glucocorticoid enhancement of serotonergic facilitation of cat spinal monosynaptic motor neuron excitation (1980) (11)
- Glucocorticoid effects on serotonergic and noradrenergic facilitation of spinal monosynaptic transmission (1980) (10)
- Neuroprotective effects of the GABAA receptor partial agonist U-101017 in 3-acetylpyridine-treated rats (1997) (10)
- The Contributing Role of Lipid Peroxidation and Protein Oxidation in the Course of CNS Injury Neurodegeneration and Neuroprotection (2015) (10)
- Preclinical Common Data Elements for Traumatic Brain Injury Research: Progress and Use Cases. (2020) (9)
- Two Novel Pyrrolopyrimidine Lipid Peroxidation Inhibitors U-101033E and U-104067F Protect Facial Motor Neurons Following Neonatal Axotomy (1996) (9)
- Facilitatory effects of piracetam on excitability of motor nerve terminals and neuromuscular transmission (1987) (9)
- Translational Principles of Neuroprotective and Neurorestorative Therapy Testing in Animal Models of Traumatic Brain Injury (2016) (8)
- A comparison of the effects of tirilazad on subarachnoid hemorrhage-induced blood-brain barrier permeability in male and female rats. (1997) (8)
- Effects of Phenelzine Administration on Mitochondrial Function, Calcium Handling, and Cytoskeletal Degradation after Experimental Traumatic Brain Injury. (2019) (8)
- Non-serotonergic depression of spinal monosynaptic reflex transmission by 5-hydroxytryptophan (1981) (8)
- Protective effects of tirilazad mesylate in a cellular model of peroxynitrite toxicity. (1996) (8)
- Glucocorticoid modification of the responsiveness of a fast (type 2) neuromuscular system to edrophonium and d-tubocurarine (1980) (8)
- Acute cardiovascular response to a single large intravenous dose of methylprednisolone and its effects on the responses to norepinephrine and isoproterenol. (1984) (7)
- Corticosteroid therapy in experimental cord injury. (1984) (7)
- Mutant Cu,Zn superoxide dismutase in motor neuron disease (1998) (7)
- Healthy dietary intake moderates the effects of age on brain iron concentration and working memory performance (2021) (7)
- Neuroprotective Effects of the Pyrrolopyrimidine U-104067F in 3-Acetylpyridine-Treated Rats (1996) (7)
- Preserving Function in Acute Nervous System Injury (2005) (6)
- Protective effects of phenelzine administration on synaptic and non-synaptic cortical mitochondrial function and lipid peroxidation-mediated oxidative damage following TBI in young adult male rats (2020) (6)
- Glucocorticoid enhancement of guanidine neuromuscular facilitation (1980) (6)
- Characteristics of lipid peroxidative conduction block induced by an organic hydroperoxide in axons of isolated frog nerve. (1985) (6)
- Pathophysiology, Consequences and Pharmacological Prevention of Post-Traumatic CNS Ischemia (1986) (6)
- Lazaroids: potent inhibitors of iron-dependent lipid peroxidation for neurodegenerative disorders (1993) (6)
- Comparison of two ester prodrugs of methylprednisolone on early neurologic recovery in a murine closed head injury model. (1989) (6)
- Cyclophosphamide is neuroprotective in a gerbil model of transient severe focal cerebral ischemia: correlation with effects of tirilazad mesylate (U-74006F). (1996) (5)
- First SN Discoveries from the Dark Energy Survey (2012) (5)
- Mechanisms of neuronal degeneration secondary to central nervous system trauma or ischemia. (1989) (5)
- Protective effect of the 21-aminosteroid lipid peroxidation inhibitor tirilazad mesylate (U74006F) on hepatic endothelium in experimental hemorrhagic shock. (1993) (5)
- Pharmacological Interventions in CNS Ischemia and Trauma: Studies With High-Dose Methylprednisolone (1986) (4)
- Pathophysiology of spinal cord injury. Current and future therapies. (1989) (4)
- Comparison of tirilazad mesylate (U-74006F) and methylprednisolone sodium succinate treatments in experimental allergic encephalomyelitis in the guinea pig. (1996) (4)
- Stroke/Traumatic Brain and Spinal Cord Injuries (2007) (3)
- Beneficial effects of the 21-aminosteroid U74006F in acute CNS trauma and hypovolemic shock. (1987) (3)
- Cellular and molecular mechanisms of neuroprotection and plasticity after traumatic brain injury (2017) (3)
- Non-surgical management of spinal cord injuries: a review of studies with the glucocorticoid steroid methylprednisolone. (1987) (3)
- Lazaroids: Novel Cerebroprotective Antioxidants (1992) (3)
- 10 Free Radicals and Neuroprotection in Traumatic Brain and Spinal Cord Injury (2008) (2)
- Pharmacological inhibition of lipid peroxidative damage by the 21-aminosteroid U-74389G improves cortical mitochondrial function following traumatic brain injury in young adult male rats (2020) (2)
- Oxidative Damage Mechanisms in Traumatic Brain Injury and Antioxidant Neuroprotective Approaches (2018) (2)
- Basic mechanisms of spinal cord injury (SCI) (2012) (2)
- Antioxidant Therapeutic Strategies in CNS Disorders (1997) (2)
- Gender Differences in Acute Cerebral Ischemia: Neuroprotective Mechanisms of Estrogen (2001) (2)
- Lipid peroxidation. (1996) (1)
- Carbonyl Scavenging as an Antioxidant Neuroprotective Strategy for Acute Traumatic Brain Injury (2017) (1)
- The lazaroids and tirilazad mesylate U74006F: A pharmacologic approach to CNS trauma (1990) (1)
- Emerging strategies for the treatment of Alzheimers disease at the Millennium (1999) (1)
- Attenuation of motor nerve terminal repetitive discharge by the 21-aminosteroid tirilazad: evidence of a neural calcium antagonist action (1998) (1)
- The 21-Aminosteroid Antioxidant Tirilazad Mesylate in CNS Injury and Hemorrhagic Shock (1992) (1)
- Methylprednisolone, head trauma, and brain protection. (1993) (1)
- Assessments of Oxidative Damage and Lipid Peroxidation After Traumatic Brain Injury and Spinal Cord Injury (2012) (1)
- Actions of guanidine hydrochloride on cat spinal monosynaptic reflex transmission (1983) (1)
- Role of Amyloid Protein Precursor and Apolipoprotein E in Stroke (1995) (1)
- Investigation of Infection of Sensory System Tissue (2021) (0)
- Treatment of Experimental Central Nervous System Trauma and Ischemia: Use of a Novel 21-Aminosteroid (1990) (0)
- Strategies Which Decrease Post-Reperfusion Lipid Peroxidation (1993) (0)
- Age-related phospholipid hydroperoxide levels in gerbil brain measured by HPLC-chemiluminescence assay and their relation to hydroxyl radical stress--clinical implications. (1994) (0)
- Therapeutic Targeting of Neuronal Mitochondria in Brain Injury (2015) (0)
- Neuroprotecive Efficacy and Mechanisms of the Lazaroids (2019) (0)
- Role of Oxygen Radicals in Cerebral Edema Mechanisms: Rationale for the Use of Steroids (1991) (0)
- 413 Effects of the brain-penetrating lipid peroxidation inhibitor U-104067F on amyloid precursor protein, apolipoprotein E, glial fibrillary acidic protein, and amyloid immunostaining in the gerbil forebrain ischemia model (1996) (0)
- ROMANTIC ECOCRITICISM: ORIGINS AND LEGACIES (2021) (0)
- S15.4. Lazaroid drug therapy for brain injury: From cell membranes to humans (1995) (0)
- babapenun in a Transgenic Model of ~dd AmyotropfUc Lateral sclerosis (1996) (0)
- 74 – 21-Aminosteroids (1997) (0)
- The Role of Lipid Peroxidation in Ischemic Central Nervous System Injury (1989) (0)
- The use of pramipexole as a neuroprotective agent (1995) (0)
- Neuroprotectants: Reactive Oxygen Species (ROS) Based (2017) (0)
- Abstracts from the Spinal Cord Research Foundation’s 20th Anniversary Symposium (1997) (0)
- 26th National Neurotrauma Symposium (2008) (0)
- Free radicals and neural injury (1991) (0)
- Utility of the 21-Aminosteroids in Spinal Cord Injury (1998) (0)
- Glucocorticoid modification of spinal dopamine receptor activation by apomorphine (1983) (0)
- 2611 – GLUCOCORTICOID EFFECTS ON SPINAL CORD EXCITATORY AND INHIBITORY SYNAPTIC FUNCTION (1978) (0)
- Thyrotropin-releasing hormone for spinal trauma. (1982) (0)
- Lipid peroxidation blockade: neuroprotection from cell membranes to humans (1998) (0)
- Protective Effects of the Lipid Peroxidation Inhibitor Alpha Tocopherol in Experimental SCI (2003) (0)
- Synthesis of Novel 2,4‐Diaminopyrrolo(2,3‐d)pyrimidines with Antioxidant, Neuroprotective, and Antiasthma Activity. (1996) (0)
- Suloctidil treatment prevents the development of post-traumatic feline spinal cord ischemia. (1985) (0)
- Quantitative Analysis of Effects of K-Opioid Agonists on Postischemic Hippocampal Neuronal Necrosis in Gerbils (2005) (0)
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