Eduardo G. Lapetina
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Eduardo G. Lapetinabiology Degrees
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Molecular Biology
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Neuroscience
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Biochemistry
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Biology
Eduardo G. Lapetina's Degrees
- Bachelors Biochemistry University of Buenos Aires
- PhD Molecular Biology University of California, San Francisco
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(Suggest an Edit or Addition)Eduardo G. Lapetina's Published Works
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Published Works
- Nitric oxide-induced S-nitrosylation of glyceraldehyde-3-phosphate dehydrogenase inhibits enzymatic activity and increases endogenous ADP-ribosylation. (1992) (376)
- Resistance of Crohn's disease T cells to multiple apoptotic signals is associated with a Bcl-2/Bax mucosal imbalance. (1999) (372)
- Activation of a cytosolic ADP-ribosyltransferase by nitric oxide-generating agents. (1989) (337)
- Nitric Oxide-induced S-Glutathionylation and Inactivation of Glyceraldehyde-3-phosphate Dehydrogenase* (1999) (301)
- Phospholipase A2 activity specific for phosphatidic acid. A possible mechanism for the production of arachidonic acid in platelets. (1981) (290)
- The rapid formation of inositol phosphates in human platelets by thrombin is inhibited by prostacyclin. (1984) (242)
- Exogenous sn-1,2-diacylglycerols containing saturated fatty acids function as bioregulators of protein kinase C in human platelets. (1985) (238)
- Gangliosides and acetylcholinesterase in isolated membranes of the rat-brain cortex. (1967) (236)
- Rapid decrease of phosphatidylinositol 4,5-bisphosphate in thrombin-stimulated platelets. (1982) (234)
- Regulation of arachidonic acid production: role of phospholipases C and A2 (1982) (233)
- Stimulation of phosphatidic acid production in platelets precedes the formation of arachidonate and parallels the release of serotonin. (1979) (226)
- Inhibition of caspase-3 by S-nitrosation and oxidation caused by nitric oxide. (1997) (219)
- Phospholipase A2 and phospholipase C activities of platelets. Differential substrate specificity, Ca2+ requirement, pH dependence, and cellular localization. (1980) (218)
- The phosphatidylinositol cycle and the regulation of arachidonic acid production (1981) (199)
- Nitric oxide-induced apoptosis in RAW 264.7 macrophages is antagonized by protein kinase C- and protein kinase A-activating compounds. (1995) (197)
- The initial action of thrombin on platelets. Conversion of phosphatidylinositol to phosphatidic acid preceding the production of arachidonic acid. (1981) (186)
- Cyclic adenosine 3',5'-monophosphate and prostacyclin inhibit membrane phospholipase activity in platelets. (1977) (186)
- 1,2-Diacylglycerol and phorbol ester inhibit agonist-induced formation of inositol phosphates in human platelets: possible implications for negative feedback regulation of inositol phospholipid hydrolysis. (1985) (170)
- Arachidonic acid stimulates the formation of 1,2-diacylglycerol and phosphatidic acid in human platelets. Degree of phospholipase C activation correlates with protein phosphorylation, platelet shape change, serotonin release, and aggregation. (1983) (165)
- Formation of lysophosphatidylinositol in platelets stimulated with thrombin or ionophore A23187. (1982) (158)
- Association of p21ras with phosphatidylinositol 3-kinase. (1991) (156)
- The alpha 1C-adrenergic receptor: characterization of signal transduction pathways and mammalian tissue heterogeneity. (1991) (144)
- Nitric oxide: a signal for ADP-ribosylation of proteins. (1994) (143)
- Pertussis toxin inhibits chemotactic peptide-stimulated generation of inositol phosphates and lysosomal enzyme secretion in human leukemic (HL-60) cells. (1985) (141)
- Activation of phospholipase C is dissociated from arachidonate metabolism during platelet shape change induced by thrombin or platelet-activating factor. Epinephrine does not induce phospholipase C activation or platelet shape change. (1984) (137)
- LIPIDS AND PROTEOLIPIDS IN ISOLATED SUBCELLULAR MEMBRANES OF RAT BRAIN CORTEX * (1968) (133)
- Platelet-activating factor stimulates the phosphatidylinositol cycle. Appearance of phosphatidic acid is associated with the release of serotonin in horse platelets. (1982) (132)
- Phosphatidylinositol-specific phospholipase-C of platelets: association with 1,2-diacyglycerol-kinase and inhibition by cyclic-AMP. (1979) (129)
- Cyclic AMP-dependent Activation of Rap1b (*) (1995) (128)
- Superoxide Formation and Macrophage Resistance to Nitric Oxide-mediated Apoptosis* (1997) (124)
- Specific binding of [alpha-32P]GTP to cytosolic and membrane-bound proteins of human platelets correlates with the activation of phospholipase C. (1987) (119)
- A role for cyclooxygenase products in the formation of phosphatidic acid in stimulated human platelets. Differential mechanisms of action of thrombin and collagen. (1983) (117)
- Phosphorylation of nitric oxide synthase by protein kinase A. (1991) (115)
- Phosphatidylinositol metabolism in cells receiving extracellular stimulation (1973) (114)
- Hepatocytes and macrophages express an identical cytokine inducible nitric oxide synthase gene. (1993) (112)
- Erythropoietin induces p21ras activation and p120GAP tyrosine phosphorylation in human erythroleukemia cells. (1992) (111)
- A membrane-bound activity catalysing phosphatidylinositol breakdown to 1,2-diacylglycerol, D-myoinositol 1:2-cyclic phosphate an D-myoinositol 1-phosphate. Properties and subcellular distribution in rat cerebral cortex. (1973) (109)
- A ras-related protein is phosphorylated and translocated by agonists that increase cAMP levels in human platelets. (1989) (108)
- Macrophages resistant to endogenously generated nitric oxide-mediated apoptosis are hypersensitive to exogenously added nitric oxide donors: dichotomous apoptotic response independent of caspase 3 and reversal by the mitogen-activated protein kinase kinase (MEK) inhibitor PD 098059. (1998) (108)
- A role for Gi in control of thrombin receptor-phospholipase C coupling in human platelets. (1988) (108)
- Sequential and rapid activation of select caspases during apoptosis of normal intestinal epithelial cells. (1998) (95)
- Collagen stimulates [3H]inositol trisphosphate formation in indomethacin-treated human platelets. (1985) (93)
- The diglyceride kinase of rat cerebral cortex. (1971) (91)
- Shape change induced in human platelets by platelet-activating factor. Correlation with the formation of phosphatidic acid and phosphorylation of a 40,000-dalton protein. (1983) (89)
- Thrombin stimulates the production of a novel polyphosphoinositide in human platelets. (1990) (83)
- Phorbol 12,13-dibutyrate and 1-oleyl-2-acetyldiacylglycerol stimulate inositol trisphosphate dephosphorylation in human platelets. (1986) (82)
- Glutathione levels determine apoptosis in macrophages. (1998) (79)
- Dual coupling of the cloned 5-HT1A receptor to both adenylyl cyclase and phospholipase C is mediated via the same Gi protein. (1991) (77)
- Receptor-stimulated phospholipase A2 activation is coupled to influx of external calcium and not to mobilization of intracellular calcium in C62B glioma cells. (1989) (77)
- Rap1-B is phosphorylated by protein kinase A in intact human platelets. (1990) (74)
- Identification of a Novel RalGDS-related Protein as a Candidate Effector for Ras and Rap1* (1996) (74)
- Heat shock proteins and macrophage resistance to the toxic effects of nitric oxide. (1996) (72)
- The role of phospholipase C in platelet responses. (1983) (71)
- Platelet-activating factor stimulates metabolism of phosphoinositides in horse platelets: possible relationship to Ca2+ mobilization during stimulation. (1983) (70)
- Decanoyl lysophosphatidic acid induces platelet aggregation through an extracellular action. Evidence against a second messenger role for lysophosphatidic acid. (1985) (68)
- Association of phosphorylated insulin-like growth factor-I receptor with the SH2 domains of phosphatidylinositol 3-kinase p85. (1992) (67)
- Mutational analysis of the cAMP-dependent protein kinase-mediated phosphorylation site of Rap1b. (1993) (64)
- Ca2+ mobilization primes protein kinase C in human platelets. Ca2+ and phorbol esters stimulate platelet aggregation and secretion synergistically through protein kinase C. (1988) (63)
- Prostaglandin endoperoxide analogues stimulate phospholipase C and protein phosphorylation during platelet shape change. (1985) (63)
- Properties of a novel nitric oxide-stimulated ADP-ribosyltransferase. (1990) (62)
- Phosphorylation of a Ras-related GTP-binding protein, Rap-1b, by a neuronal Ca2+/calmodulin-dependent protein kinase, CaM kinase Gr. (1991) (61)
- Rapid inactivation of cyclooxygenase activity after stimulation of intact platelets. (1979) (61)
- Structure and Function of rap Proteins in Human Platelets (1994) (60)
- Inflammatory mediators are perpetuated in macrophages resistant to apoptosis induced by hypoxia. (1997) (59)
- RAP2B: a RAS-related GTP-binding protein from platelets. (1990) (59)
- Rap1B and Rap2B Translocation to the Cytoskeleton by von Willebrand Factor Involves FcγII Receptor-mediated Protein Tyrosine Phosphorylation* (1999) (57)
- Stimulation by acetylcholine of phosphatidylinositol labelling. Subcellular distribution in rat cerebral-cortex slices. (1972) (57)
- Role of rap1B and p21ras GTPase-activating protein in the regulation of phospholipase C-gamma 1 in human platelets. (1992) (57)
- Action of corticosteroids in regulation of prostaglandin biosynthesis in cultured fibroblasts. (1978) (57)
- Ionophore A-23187- and thrombin-induced platelet aggregation: independence from cycloxygenase products. (1978) (56)
- Phosphatidylinositol 3-kinase is a target for protein tyrosine nitration. (1998) (56)
- Metabolism of inositides and the activation of platelets. (1983) (55)
- Properties and distribution of phosphatidylinositol-specific phospholipase C in human and horse platelets. (1983) (54)
- Intracellular activation of protein kinase C and regulation of the surface transferrin receptor by diacylglycerol is a spontaneously reversible process that is associated with rapid formation of phosphatidic acid. (1986) (54)
- Activation of platelet phospholipase C by fluoride is inhibited by elevation of cyclic AMP. (1989) (53)
- Degradation of phosphatidylinositol-4,5-bisphosphate is insensitive to CA2+ mobilization in stimulated platelets. (1982) (53)
- Production of cyclic inositol phosphate in stimulated tissues. (1972) (52)
- Thrombin induces serotonin secretion and aggregation independently of inositol phospholipids hydrolysis and protein phosphorylation in human platelets permeabilized with saponin. (1985) (52)
- Evidence for multiple metabolic pools of phosphatidylinositol in stimulated platelets. (1982) (51)
- 1,2-Didecanoylglycerol and phorbol 12,13-dibutyrate enhance anterior pituitary hormone secretion in vitro. (1985) (50)
- Cholinergic stimulation of arachidonic acid and phosphatidic acid metabolism in C62B glioma cells. (1986) (48)
- Acetylcholine stimulates selective liberation and re-esterification of arachidonate and accumulation of inositol phosphates and glycerophosphoinositol in C62B glioma cells. (1987) (48)
- Arachidonic acid mediates angiotensin II effects on p21ras in renal proximal tubular cells via the tyrosine kinase-Shc-Grb2-Sos pathway. (1998) (47)
- Adrenergic stimulation of phosphatidylinositol labelling in rat vas deferens. (1974) (47)
- Erythropoietin rapidly induces tyrosine phosphorylation in the human erythropoietin-dependent cell line, UT-7. (1992) (47)
- Prenyl group identification of rap2 proteins: a ras superfamily member other than ras that is farnesylated. (1993) (46)
- Inositol 1,4,5-trisphosphate induces aggregation and release of 5-hydroxytryptamine from saponin-permeabilized human platelets. (1986) (45)
- Platelet aggregation induced by alpha 2-adrenoceptor and protein kinase C activation. A novel synergism. (1989) (44)
- Inhibition of ras-induced germinal vesicle breakdown in Xenopus oocytes by rap-1B. (1991) (44)
- Neomycin inhibits inositol phosphate formation in human platelets stimulated by thrombin but not other agonists (1986) (41)
- Rapid acylation and deacylation of arachidonic acid into phosphatidic acid of horse neutrophils. (1980) (41)
- A novel pathway for the formation of phosphatidylinositol 3,4-bisphosphate. Phosphorylation of phosphatidylinositol 3-monophosphate by phosphatidylinositol-3-monophosphate 4-kinase. (1990) (41)
- Association of the low molecular weight GTP-binding protein rap2B with the cytoskeleton during platelet aggregation. (1993) (40)
- Prostacyclin inhibits platelet aggregation induced by phorbol ester or Ca2+ ionophore at steps distal to activation of protein kinase C and Ca2+-dependent protein kinases. (1989) (39)
- Glyceraldehyde-3-phosphate dehydrogenase is required for the transport of nitric oxide in platelets. (1993) (39)
- Leupeptin selectively inhibits human platelet responses induced by thrombin and trypsin; a role for proteolytic activation of phospholipase C. (1985) (38)
- Neuropeptide Y mobilizes intracellular Ca2+ and increases inositol phosphate production in human erythroleukemia cells. (1989) (37)
- Muscarinic cholinergic stimulation of phosphatidylinositol turnover in isolated rat superior cervical sympathetic ganglia (1976) (35)
- cDNA sequence of a new ras-related gene (rap2b) isolated from human platelets with sequence homology to rap2. (1990) (35)
- myo-Inositol 1,4,5-trisphosphate stimulates protein phosphorylation in saponin-permeabilized human platelets. (1984) (35)
- Glucocorticoids inhibit the liberation of arachidonate but not the rapid production of phospholipase C-dependent metabolites in acetylcholine-stimulated C62B glioma cells. (1987) (34)
- Insulin like growth factor-I induces limited association of phosphatidylinositol 3-kinase to its receptor. (1992) (34)
- The effect of iloprost on the ADP-ribosylation of Gsα (the α-subunit of Gs) (1989) (33)
- Epinephrine induces changes in the subcellular distribution of the inhibitory GTP-binding protein Gi alpha-2 and a 38-kDa phosphorylated protein in the human platelet. (1989) (33)
- Effect of protein kinase A on inositide metabolism and rap 1 G-protein in human erythroleukemia cells. (1990) (33)
- Incorporation of synthetic 1,2‐diacylglycerol into platelet phosphatidylinositol is increased by cyclic AMP (1986) (33)
- Lysophosphatidic acid potentiates the thrombin-induced production of arachidonate metabolites in platelets. (1981) (33)
- GTP and GDP will stimulate platelet cytosolic phospholipase C independently of Ca2+. (1986) (32)
- Effect of pertussis toxin on the phosphodiesteratic cleavage of the polyphosphoinositides by guanosine 5'-O-thiotriphosphate and thrombin in permeabilized human platelets. (1986) (32)
- Carboxyl methylation of platelet rap1 proteins is stimulated by guanosine 5'-(3-O-thio)triphosphate. (1991) (32)
- Subcellular Localization of α-Subunits of Trimeric G-Proteins in Human Platelets (1997) (32)
- Treatment of human platelets with trypsin, thrombin, or collagen inhibits the pertussis toxin-induced ADP-ribosylation of a 41-kDa protein. (1986) (31)
- In vivo and in vitro action of antisera against isolated nerve endings of brain cortex (1966) (30)
- Functional relationship between cyclic AMP-dependent protein phosphorylation and platelet inhibition. (1990) (30)
- Regulation of platelet glycoprotein IIb/IIIa (integrin alpha IIB beta 3) function via the thrombin receptor. (1995) (29)
- Epinephrine induces association of pp60src with Giα in human platelets (1992) (29)
- The effect of antiserum against nerve-ending membranes from cat cerebral cortex on the ultrastructure of isolated nerve endings and mollusc neurons. (1968) (28)
- Cellular Adaptive Responses to Low Oxygen Tension: Apoptosis and Resistance (1997) (28)
- Turnover rates for glycerol, acetate and orthophosphate in phospholipids of the rat cerebral cortex. (1969) (28)
- Dual mechanisms of platelet hormone receptor desensitization. Differential importance between agonists of protein kinase C-dependent and -independent pathways. (1989) (27)
- Identification of α-Subunits of Trimeric GTP-Binding Proteins in Human Platelets by RT-PCR (1995) (26)
- Measurement of inositol phospholipid turnover in platelets. (1987) (26)
- No direct correlation between Ca2+ mobilization and dissociation of Gi during platelet phospholipase A2 activation. (1988) (26)
- Incorporation of (Me-14C)choline into phosphatidyl choline of rat cerebral cortex membranes in vitro. (1970) (26)
- Agonist-induced association of the p21ras GTPase-activating protein with phosphatidylinositol 3-kinase. (1992) (25)
- Protein thiol modification of glyceraldehyde-3-phosphate dehydrogenase as a target for nitric oxide signaling. (1995) (25)
- Agonist-induced ADP-ribosylation of a cytosolic protein in human platelets. (1990) (25)
- The turnover of phosphatidyl choline in rat cerebral cortex membranes in vivo. (1969) (25)
- Thrombolamban, the 22-kDa platelet substrate of cyclic AMP-dependent protein kinase, is immunologically homologous with the Ras family of GTP-binding proteins. (1990) (25)
- Glycoprotein IIb-IIIa and the translocation of Rap2B to the platelet cytoskeleton. (1994) (24)
- Protein kinase C-mediated formation of phosphatidylinositol 3,4-bisphosphate in human platelets. (1990) (23)
- Interaction of the low‐molecular‐weight GTP‐binding protein rap2 with the platelet cytoskeleton is mediated by direct binding to the actin filaments (1999) (22)
- Agonist-induced phosphorylation of an immunologically ras-related protein in human erythroleukemia cells. (1989) (21)
- Isoprenylation of rap2 proteins in platelets and human erythroleukemia cells. (1991) (21)
- Cytochalasins inhibit arachidonic acid metabolism in thrombin-stimulated platelets. (1982) (21)
- The effect of antiserum against nerve-ending membranes from cat cerebral cortex bioelectrical activity of mollusc neurons. (1968) (21)
- Phosphorylation of the 47 KDa protein in gamma-thrombin-stimulated human platelets does not activate phospholipase A2: evidence against lipocortin. (1986) (21)
- Adhesion of human platelets to collagen in the presence of prostacyclin, indomethacin and compound BW 755C. (1986) (21)
- Platelet Activation and Inhibition (1994) (20)
- Epinephrine suppresses rap1B.GAP-activated GTPase activity in human platelets. (1992) (19)
- 1,2-Diacylglycerols do not potentiate the action of phospholipases A2 and C in human platelets. (1984) (19)
- Differential effects of phorbol ester and diacylglycerols on inositol phosphate formation in C62B glioma cells. (1987) (19)
- Sustained proteolysis is required for human platelet activation by thrombin. (1986) (19)
- Insulin-like growth factor-1-mediated association of p85 phosphatidylinositol 3-kinase with pp 185: requirement of SH2 domains for in vivo interaction. (1994) (19)
- An overview of antiplatelet and antithrombotic drugs. (1985) (19)
- Ionophore A23187 stimulates phosphorylation of the 40,000 dalton protein in human platelets without phospholipase C activation. (1986) (18)
- Protease and cyclooxygenase inhibitors synergistically prevent activation of human platelets. (1986) (18)
- Dihomogammalinolenic acid, but not eicosapentaenoic acid, activates washed human platelets. (1984) (18)
- Glyceraldehyde-3-phosphate dehydrogenase: a target for nitric oxide signaling. (1995) (18)
- NADPH: a stimulatory cofactor for nitric oxide-induced ADP-ribosylation reaction. (1992) (18)
- The production of phosphatidylinositol trisphosphate is stimulated by thrombin in human platelets. (1991) (17)
- Deoxycholate induces the preferential hydrolysis of polyphosphoinositides by human platelet and rat corneal phospholipase C. (1985) (16)
- Thrombin and phorbol ester stimulate inositol 1,3,4,5-tetrakisphosphate 3-phosphomonoesterase in human platelets. (1990) (16)
- Phospholipid metabolism of isolated nerve endings. (1970) (16)
- Phorbol esters sensitize platelets to activation by physiological agonists (1987) (15)
- Cholinergic stimulation of phosphatidylinositol hydrolysis by rat corneal epithelium in vitro. (1987) (15)
- Prostacyclin inhibition of phosphatidic acid synthesis in human platelets is not mediated by protein kinase C. (1984) (15)
- ATP depletion in human platelets caused by permeabilization with saponin does not prevent serotonin secretion induced by collagen. (1985) (15)
- Action of Triton X-100 on lipids and proteolipids of nerve-ending membranes. (1968) (15)
- 32P INCORPORATION INTO DIFFERENT MEMBRANOUS STRUCTURES SEPARATED FROM RAT CEREBRAL CORTEX 1 (1969) (15)
- Preparation of 32P-labeled inositides and their degradation by soluble kidney enzymes. (1975) (14)
- Antisera specific for rap 1 proteins distinguish between processed and nonprocessed rap 1b. (1991) (14)
- The Na+/H+ antiporter is not involved in potentiation of thrombin-induced responses by epinephrine. (1988) (13)
- GDPβS enhances the activation of phospholipase C caused by thrombin in human platelets: Evidence for involvement of an inhibitory GTP-binding protein (1987) (13)
- Nitric oxide stimulates the phosphorylation of rap1b in human platelets and acts synergistically with iloprost. (1996) (12)
- Rap proteins: investigating their role in cell function. (1992) (12)
- The formation of [3H]inositol phosphates in human platelets by palmitoyl lysophosphatidic acid is blocked by indomethacin. (1985) (12)
- Cholinergic stimulation of phosphatidic acid formation by rat cornea in vitro. (1986) (12)
- Properties of the exchange rate of guanine nucleotides to the novel rap-2B protein. (1990) (12)
- Persistent activation of platelet membrane phospholipase C by proteolytic action of trypsin and thrombin. (1990) (11)
- Propensity for macrophage apoptosis is related to the pattern of expression and function of integrin extracellular matrix receptors. (1998) (11)
- Subcellular localization of the enzymes that dephosphorylate myo-inositol polyphosphates in human platelets. (1988) (10)
- Chapter 21. Phospholipases (1984) (10)
- Effects of acetylcholine on incorporation of [14C]glucose into phosphatidylinositol and on phosphatidylinositol breakdown in subcellular fractions from cerebral cortex (1974) (10)
- Effect of adrenergic agonists on phosphatidylinositol labelling in heart and aorta. (1976) (10)
- Maturation of Megakaryoblastic Cells Is Accompanied by Upregulation of GSα-L Subtype and Increased cAMP Accumulation (1998) (10)
- Identification of alpha-subunits of trimeric GTP-binding proteins in human platelets by RT-PCR. (1995) (9)
- The Relationship between Phospholipases A2 and C in Signal Transduction (1989) (9)
- Specific binding of [ a32 P ] GTP to cytosolic and membrane-bound proteins of human platelets correlates with the activation of phospholipase C " by (2003) (8)
- Nitric oxide-induced covalent modification of glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase. (1996) (8)
- Endogenous ADP-ribosylation in human platelets. (1988) (8)
- Peroxynitrite protects RAW 264.7 macrophage from Lipopolysaccharide/Interferon-gamma-induced cell death. (1997) (8)
- Regulation of phospholipase activity in platelets. (1978) (7)
- Iloprost-induced translocation of a 23-kDa protein that is recognized by a Gs alpha antiserum. (1989) (7)
- Phorbol esters sensitize platelets to activation by physiological agonists. (1987) (6)
- Platelet activation and inhibition. Novel signal transduction mechanisms. (1994) (6)
- Phosphatidylinositol-cleaving activity in smooth muscle from rat vas deferens. (1976) (6)
- Microinjection of Rap2B protein or RNA induces rearrangement of pigment granules in Xenopus oocytes. (1993) (6)
- Epinephrine induces association of pp60src with Gi alpha in human platelets. (1992) (5)
- Subcellular localization of alpha-subunits of trimeric G-proteins in human platelets. (1997) (5)
- Phosphatidylinositol metabolism and myoinositol 1, 2-cyclic phosphate action in smooth muscle. (1976) (4)
- Inositol 1:2-Cyclic Phosphate in Tissues (1973) (4)
- The inositide and arachidonic acid signal system. (1989) (4)
- Regulation of hormone-induced Ca2+ mobilization in the human platelets. (1990) (3)
- GDP beta S enhances the activation of phospholipase C caused by thrombin in human platelets: evidence for involvement of an inhibitory GTP-binding protein. (1987) (3)
- Relative importance of diacylglycerol, phosphatidate, lysophosphatidate, inositol trisphosphate and arachidonate metabolism in platelet receptor signalling. (1985) (3)
- The relative importance of inositol 1,4,5-trisphosphate, 1,2-diacylglycerol and phosphatidic acid in mediating human platelet activation by thrombin (1984) (3)
- Thrombin stimulates the production of phosphatidylinositol 3,4-bisphosphate in human erythroleukemia cells. (1991) (3)
- The effect of iloprost on the ADP-ribosylation of Gs alpha (the alpha-subunit of Gs). (1989) (3)
- Different Functions of Phosphoinositide Turnover and Arachidonate Metabolism for Platelet Activation (1985) (3)
- Spacial isolation of protein kinase C activation in thrombin stimulated human platelets. (1988) (3)
- Possible Glial Modulation of Neuronal Activity by Eicosanoids and Phosphoinositide Metabolites (1986) (3)
- Partial purification of a GTPase-activating protein for rap2b from bovine brain membranes. (1992) (3)
- The role of GTP-binding proteins in receptor activation of phospholipase C. (1987) (2)
- Platelet cytosolic 44-kDa protein is a substrate of cholera toxin-induced ADP-ribosylation and is not recognized by antisera against the alpha subunit of the stimulatory guanine nucleotide-binding regulatory protein. (1988) (2)
- The importance of the production of phosphatidic acid for the release of arachidonic acid in stimulated platelets (1981) (1)
- Platelets in Thrombotic and Non-thrombotic Disorders: Roles of phospholipase C and phospholipase D in receptor-mediated platelet activation (2002) (1)
- Resistance of Crohn's disease (CD) mucosal T-cells to cell death is independent of trigger: Decreased anti-Fas and nitric oxide (NO)-induced apoptosis (1998) (1)
- Eicosanoid Formation and Regulation of Phospholipase A2 (1990) (1)
- Ultrastructural and bioelectrical effects of antisera against subcellular particles from brain. (1971) (1)
- Rap1b and platelet function. (1993) (1)
- Platelet Response in Relation to Metabolism of Inositides and Protein Phosphorylation (1985) (1)
- Relationship of inositol phospholipid metabolism to phospholipase A2. (1989) (1)
- Multiple Messenger Roles for the Inhibitory GTP-Binding Protein, G i , in Human Platelets (1989) (1)
- Adrenergic and cholinergic stimulation of arachidonate and phosphatidate metabolism in cultured astroglial cells (1986) (1)
- The Relevance of Inositide Degradation and Protein Kinase C in Platelet Responses (1985) (0)
- Phosphatidylinositol turnover stimulated by acetylcholine: subcellular distribution in rat cerebral cortex. (1972) (0)
- THE ROLE OF INOSITIDES, PHOSPHOLIPASE C AND G-PROTEINS IN RECEPTOR TRANSDUCTION (1987) (0)
- The rap Protein Family: rap1A, rap1B, rap2A, and rap2B (1991) (0)
- Integrin Expression and Macrophage Resistance to Apoptosis in Atherosclerosis (1998) (0)
- The Phosphatidylinositol Response and the Activation of Platelets (1983) (0)
- Thrombin activates the adp ribosylation of a cytosolic 39 kda protein in electropermeabilized platelets (1990) (0)
- Thrombolamban, the22-kDa platelet substrate ofcyclic AMP-dependent protein kinase, isimmunologically homologous withtheRasfamily ofGTP-binding proteins (1990) (0)
- Noradrenaline stimulation of phosphatidylinositol breakdown in rat vas deferens. (1974) (0)
- PHOSPHOLIPASE A2 ACTIVATION BY A MECHANISM SEPARATE TO THAT RESPONSIBLE FOR PHOSPHOLIPASE C STIMULATION IN ALPHA-THROMBIN-STIMULATED HUMAN PLATELETS (1987) (0)
- Receptor Desensitization Is a Major Regulator of Hormone-Induced Ca 2+ Mobilization in the Human Platelet (1989) (0)
- Inositol phospholipids and GTP-binding proteins in signal transduction in stimulated human platelets. (1986) (0)
- Epinephrine suppresses raplB . GAP-activated GTPase activity in human platelets ( ras oncogenes / ras GTPase-activating protein / ras superfamily of proteins / platelet activation ) (0)
- Prostaglandin endoperoxide analogues stimulate formation of 1,2-diacylglycerol and myo-inositol 1,4,5-triphosphate in human platelets. (1985) (0)
- [24] – Nitric Oxide in NAD/NADH-Dependent Protein Modification (1996) (0)
- Antipain or leupeptin in combination with aspirin or indomethacin synergistically inhibit human platelet activation by thrombin and trypsin. (1987) (0)
- NOVEL GTP-BINDING PROTEINS OF CYTOSOLIC AND MEMBRANE FRACTIONS OF HUMAN PLATELETS (1987) (0)
- Nitric Oxide Signaling in Macrophage Apoptosis (1997) (0)
- Phosphorylation of inositol phospholipids in human platelets (1987) (0)
- Inositol phospholipids and phospholipase C in platelet receptor transduction. (1988) (0)
- Documentation of efficacy of drugs affecting apoptosis and other atheroma-related mechanisms. (1998) (0)
- The Role of Low Molecular Weight GTP-Binding Proteins in Human Platelets (1997) (0)
- The effect of iloprost on the ADP-ribosylation of G5x (the x-subunit of G ) (2005) (0)
- Rapidinactivation ofcyclooxygenase activity after stimulation ofintact platelets (lipoxygenase/arachidonate/phospholipases/aggregation/self-regulation) (1979) (0)
- BIOCHEMICAL PATTERNS IN ISOLATED MEMBRANES OF THE CNS (1969) (0)
- Rap1b interacts with a ral guanine nucleotide dissociation stimulator (RalGDS) homolog (1995) (0)
- protein phosphorylation during platelet shape change Prostaglandin endoperoxide analogues stimulate phospholipase C and (2011) (0)
- THROMBIN-INDUCED RELEASE OF INTRA-PLATELET CA2+ STORES IS INHIBITED BY PROSTACYCLIN, BUT GTP- AND IP3-INDUCED RELEASE IS UNAFFECTED (1987) (0)
- Macrophage Resistance to Apoptosis in Vascular Diseases (2002) (0)
- 28. Nitric oxide-induced apoptosis of RAW264.7 peritoneal macrophages: relationship between apoptosis and integrin expression profiles (2017) (0)
- Role of Rap1B and Its Phosphorylation in Cellular Function: A Working Model (1993) (0)
- Microinjection ofRap2Bprotein orRNAinduces rearrangement ofpigment granules inXenopus oocytes (1993) (0)
- Potentiation of noradrenaline responses in isolated smooth muscles by cyclic-inositol-phosphate. (1974) (0)
- SYNERGISM OF Gi-DISSOCIATION AND PROTEIN KINASE C STIMULATION IN PLATELET ACTIVATION (1987) (0)
- ENZYMES THAT DEPHOSPHORYLATE INOSITOL PHOSPHATES IN HUMAN PLATELETS (1987) (0)
- Inositol phospholipids and proximal metabolites. A: Quantitation and metabolism in cells, permeable cells, and cell-free systems. ― B: Regulation of lipid synthesis. ― C: Guanine nucleotide-binding component (1987) (0)
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What Schools Are Affiliated With Eduardo G. Lapetina?
Eduardo G. Lapetina is affiliated with the following schools:
