E. J. Jr. Merck Sharp Cragoe
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Chemistry
E. J. Jr. Merck Sharp Cragoe's Degrees
- PhD Chemistry University of California, Berkeley
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(Suggest an Edit or Addition)E. J. Jr. Merck Sharp Cragoe's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Amiloride and its analogs as tools in the study of ion transport (1988) (524)
- Blockade of the Na+/H+ antiport abolishes growth factor-induced DNA synthesis in fibroblasts. Structure-activity relationships in the amiloride series. (1984) (272)
- Control of intracellular pH and growth by fibronectin in capillary endothelial cells (1990) (240)
- An aspartate conserved among G-protein receptors confers allosteric regulation of alpha 2-adrenergic receptors by sodium. (1990) (239)
- Angiotensin II-stimulated Na+/H+ exchange in cultured vascular smooth muscle cells. Evidence for protein kinase C-dependent and -independent pathways. (1987) (206)
- NMR measurements of Na+ and cellular energy in ischemic rat heart: role of Na(+)-H+ exchange. (1993) (194)
- Structure-activity relationships of amiloride and certain of its analogues in relation to the blockade of the Na+/H+ exchange system. (1984) (184)
- Inhibition of Na+/Ca2+ exchange in membrane vesicle and papillary muscle preparations from guinea pig heart by analogs of amiloride. (1984) (173)
- Amiloride inhibits phorbol ester-stimulated Na+/H+ exchange and protein kinase C. An amiloride analog selectively inhibits Na+/H+ exchange. (1985) (173)
- Role of protein kinase C and the Na+/H+ antiporter in suppression of apoptosis by granulocyte macrophage colony-stimulating factor and interleukin-3. (1992) (168)
- Role of the Na+/H+ antiporter in rat proximal tubule bicarbonate absorption. (1987) (166)
- Evidence that Na+/H+ exchange regulates receptor-mediated phospholipase A2 activation in human platelets. (1986) (159)
- Demonstration of a [K+,Cl-]-cotransport system in human red cells by its sensitivity to [(dihydroindenyl)oxy]alkanoic acids: regulation of cell swelling and distinction from the bumetanide-sensitive [Na+,K+,Cl-]-cotransport system. (1988) (158)
- Ethylisopropyl-amiloride: a new and highly potent derivative of amiloride for the inhibition of the Na+/H+ exchange system in various cell types. (1983) (146)
- Regulation of intracellular pH in cultured hippocampal neurons by an amiloride-insensitive Na+/H+ exchanger. (1991) (144)
- Regulation of human neutrophil chemotaxis by intracellular pH. (1986) (142)
- Epithelial chloride channel. Development of inhibitory ligands (1987) (138)
- Inhibition of Na+/Ca2+ exchange in pituitary plasma membrane vesicles by analogues of amiloride. (1985) (133)
- Intracellular pH regulation in resting and contracting segments of rat mesenteric resistance vessels. (1988) (131)
- Blastocoel expansion in the preimplantation mouse embryo: role of extracellular sodium and chloride and possible apical routes of their entry. (1989) (129)
- Inhibitors of Na+/H+ exchange block epinephrine- and ADP-induced stimulation of human platelet phospholipase C by blockade of arachidonic acid release at a prior step. (1986) (126)
- Regulation of intracellular pH in human platelets. Effects of thrombin, A23187, and ionomycin and evidence for activation of Na+/H+ exchange and its inhibition by amiloride analogs. (1986) (125)
- Inhibition of Na+/Ca2+ exchange enhances delayed neuronal death elicited by glutamate in cerebellar granule cell cultures (1991) (124)
- Characterization of potent Na+/H+ exchange inhibitors from the amiloride series in A431 cells. (1984) (121)
- Inhibitors of Na+/H+ exchange block stimulus-provoked arachidonic acid release in human platelets. Selective effects on platelet activation by epinephrine, ADP, and lower concentrations of thrombin. (1985) (120)
- Glucocorticoid stimulation of ileal Na+ absorptive cell brush border Na+/H+ exchange and association with an increase in message for NHE-3, an epithelial Na+/H+ exchanger isoform. (1993) (120)
- Relations among sodium pump inhibition, Na-Ca and Na-H exchange activities, and Ca-H interaction in cultured chick heart cells. (1987) (119)
- Thrombin signal transduction mechanisms in rat vascular smooth muscle cells. Calcium and protein kinase C-dependent and -independent pathways. (1990) (116)
- Inhibition of chemotactic factor-activated Na+/H+ exchange in human neutrophils by analogues of amiloride: structure-activity relationships in the amiloride series. (1986) (111)
- Cation transport probes: the amiloride series. (1990) (107)
- Ethylisopropylamiloride-sensitive pH control mechanisms modulate vascular smooth muscle cell growth. (1991) (100)
- Effects of proton buffering and of amiloride derivatives on reperfusion arrhythmias in isolated rat hearts. Possible evidence for an arrhythmogenic role of Na(+)-H+ exchange. (1990) (98)
- Cloning, sequencing, and expression of the gene encoding the porcine alpha 2-adrenergic receptor. Allosteric modulation by Na+, H+, and amiloride analogs. (1990) (98)
- Chemical modification of cell proliferation and fluid secretion in renal cysts. (1989) (96)
- Interleukin 2 induces a rapid increase in intracellular pH through activation of a Na+/H+ antiport. Cytoplasmic alkalinization is not required for lymphocyte proliferation. (1985) (91)
- Thrombin activation of the Na+/H+ exchanger in vascular smooth muscle cells. Evidence for a kinase C-independent pathway which is Ca2+-dependent and pertussis toxin-sensitive. (1987) (86)
- Regulation of porcine brain alpha 2-adrenergic receptors by Na+,H+ and inhibitors of Na+/H+ exchange. (1987) (86)
- Thrombin-stimulated events in cultured vascular smooth-muscle cells. (1991) (85)
- Amiloride and its analogs as tools to inhibit Na+ transport via the Na+ channel, the Na+/H+ antiport and the Na+/Ca2+ exchanger. (1988) (85)
- Effects of muscarinic, alpha-adrenergic, and substance P agonists and ionomycin on ion transport mechanisms in the rat parotid acinar cell. The dependence of ion transport on intracellular calcium (1989) (84)
- Activation of the Na+/H+ and Cl-/HCO3- exchange by stimulation of acid secretion in the parietal cell. (1988) (82)
- Effects of extracellular ATP on ion transport systems and [Ca2+]i in rat parotid acinar cells. Comparison with the muscarinic agonist carbachol (1990) (82)
- Na-H exchange is a major pathway for Na influx in rat vascular smooth muscle. (1986) (81)
- Therapeutic potential of analogues of amiloride: inhibition of the regulation of intracellular pH as a possible mechanism of tumour selective therapy. (1993) (77)
- Intracellular pH in human arterial smooth muscle. Regulation by Na+/H+ exchange and a novel 5-(N-ethyl-N-isopropyl)amiloride-sensitive Na(+)- and HCO3(-)-dependent mechanism. (1990) (76)
- The pH of spontaneously beating cultured rat heart cells is regulated by an ATP-calmodulin-dependent Na+/H+ antiport. (1989) (74)
- Alpha 1-adrenoceptor stimulation increases intracellular pH and Ca2+ in cardiomyocytes through Na+/H+ and Na+/Ca2+ exchange. (1990) (74)
- Na+/Ca2+ antiport in cultured arterial smooth muscle cells. Inhibition by magnesium and other divalent cations. (1987) (74)
- pH regulation in spread cells and round cells. (1990) (73)
- Chloride transport activation by plasma osmolarity during rapid adaptation to high salinity of Fundulus heteroclitus (1995) (72)
- Stimulation by glutamate receptors of arachidonic acid release depends on the Na+/Ca2+ exchanger in neuronal cells. (1993) (72)
- Na+-H+ exchanger of human placental brush-border membrane: identification and characterization. (1986) (69)
- Amiloride, a specific inhibitor for the Na+-driven flagellar motors of alkalophilic Bacillus. (1988) (69)
- Dependence of Na+/H+ antiport activation in cultured rat aortic smooth muscle on calmodulin, calcium, and ATP. Evidence for the involvement of calmodulin-dependent kinases. (1988) (68)
- Characterization of Na+-linked and Na+-independent Cl-/HCO3- exchange systems in Chinese hamster lung fibroblasts. (1988) (67)
- Immunocytochemical and functional characterization of Na+ conductance in adult alveolar pneumocytes. (1992) (67)
- Regulation of intracellular pH in the perfused heart by external HCO3- and Na(+)-H+ exchange. (1993) (64)
- Specific inhibition of the Na(+)-driven flagellar motors of alkalophilic Bacillus strains by the amiloride analog phenamil (1990) (64)
- Increase in thermosensitivity of tumor cells by lowering intracellular pH. (1993) (64)
- Participation of a K(+) channel modulated directly by cGMP in the speract-induced signaling cascade of strongylocentrotus purpuratus sea urchin sperm. (2000) (63)
- Inhibition of sodium-calcium exchange in cardiac sarcolemmal membrane vesicles. 1. Mechanism of inhibition by amiloride analogues. (1988) (61)
- Bicarbonate determines cytoplasmic pH and suppresses mitogen-induced alkalinization in fibroblastic cells. (1988) (61)
- Inhibition of na/h antiport activity in sugar beet tonoplast by analogs of amiloride. (1987) (59)
- Estimation of the number and turnover rate of Na+/H+ exchangers in lymphocytes. Effect of phorbol ester and osmotic shrinking. (1987) (57)
- A derivative of amiloride blocks both the light-regulated and cyclic GMP-regulated conductances in rod photoreceptors (1987) (56)
- Alpha 2-adrenergic receptors accelerate Na+/H+ exchange in neuroblastoma X glioma cells. (1987) (56)
- Intracellular pH changes of cultured bovine aortic endothelial cells in response to ATP addition. (1988) (56)
- Na-H antiport in cultured rat aortic smooth muscle: its role in cytoplasmic pH regulation. (1987) (55)
- Insulin-induced cytoplasmic alkalinization and glucose transport in muscle cells. (1986) (55)
- Role of Na+/H+ exchange in thrombin-induced platelet-activating factor production by human endothelial cells. (1988) (55)
- Inhibition of K+ efflux and dehydration of sickle cells by [(dihydroindenyl)oxy]alkanoic acid: an inhibitor of the K+ Cl- cotransport system. (1989) (54)
- Differentiation of human promyelocytic HL 60 cells by retinoic acid is accompanied by an increase in the intracellular pH. The role of the Na+/H+ exchange system. (1987) (54)
- Na(+)-dependent and -independent Cl-/HCO3- exchangers in cultured rabbit esophageal epithelial cells. (1993) (53)
- Na(+)-H+ and Na(+)-dependent Cl(-)-HCO3- exchange control pHi in vascular smooth muscle. (1990) (52)
- Microtubule integrity is necessary for the epithelial barrier function of cultured thyroid cell monolayers. (1995) (52)
- The cellular pool of Na+ channels in the amphibian cell line A6 is not altered by mineralocorticoids. Analysis using a new photoactive amiloride analog in combination with anti-amiloride antibodies. (1989) (52)
- Isolation and properties of fibroblast mutants overexpressing an altered Na+/H+ antiporter. (1986) (51)
- A role for Na+/Ca2+ exchange in the generation of superoxide radicals by human neutrophils. (1990) (51)
- Intracellular-pH dependence of Na-H exchange and acid loading in quiescent and arginine vasopressin-activated mesangial cells. (1990) (50)
- Inhibition of epidermal growth factor-induced mitogenesis by amiloride and an analog: evidence against a requirement for Na+/H+ exchange. (1984) (50)
- Angiotensin II activates Na+-H+ exchange and stimulates growth in cultured vascular smooth muscle cells (1988) (49)
- Mechanisms of HCl-induced lowering of intracellular pH in rabbit esophageal epithelial cells. (1993) (48)
- Na+-Ca2+ exchange in human neutrophils. (1988) (48)
- Amiloride-sensitive Na+ pathways in capillary endothelial cell swelling during hemorrhagic shock. (1992) (48)
- The control of mediator release from RBL-2H3 cells: roles for Ca2+, Na+, and protein kinase C1. (1987) (48)
- Astrocytic swelling in traumatic-hypoxic brain injury. Beneficial effects of an inhibitor of anion exchange transport and glutamate uptake in glial cells. (1989) (47)
- Na+/H+ exchanger activity in the pig kidney epithelial cell line, LLC-PK1: inhibition by amiloride and its derivatives. (1985) (47)
- Evidence for a halide-binding site in halorhodopsin. (1983) (46)
- Amiloride and Its Analogs: Unique Cation Transport Inhibitors (1992) (44)
- The Na(+)-H+ exchanger of the placental brush-border membrane is pharmacologically distinct from that of the renal brush-border membrane. (1990) (44)
- Angiotensin II and potassium activate different calcium entry mechanisms in rat adrenal glomerulosa cells. (1989) (44)
- Studies of pHi in rabbit esophageal basal and squamous epithelial cells in culture. (1992) (44)
- Inhibition of Na+/H+ exchange in the rat is associated with decreased ursodeoxycholate hypercholeresis, decreased secretion of unconjugated urodeoxycholate, and increased ursodeoxycholate glucuronidation. (1988) (43)
- Osmotic activation of Na(+)-H+ exchange in human endothelial cells. (1990) (42)
- Inhibition of synaptosomal membrane Na+-Ca2+ exchange transport by amiloride and amiloride analogues. (1985) (42)
- Fetal lung epithelial cells contain two populations of amiloride-sensitive Na+ channels. (1993) (40)
- Characterisation of proton fluxes across the cytoplasmic membrane of the yeast Saccharomyces cerevisiae. (1991) (40)
- Photoaffinity labeling of the epithelial sodium channel. (1986) (40)
- Improved recovery from a traumatic-hypoxic brain injury in cats by intracisternal injection of an anion transport inhibitor. (1987) (39)
- Kinetics and peculiarities of thermal inactivation of volume-induced Na+/H+ exchange, Na+,K+,2Cl- cotransport and K+,Cl- cotransport in rat erythrocytes. (1993) (37)
- A Na(+)-dependent Ca2+ exchanger generates the sustained increase in intracellular Ca2+ required for T cell activation. (1992) (37)
- Ca2+ mobilization can occur independent of acceleration of Na+/H+ exchange in thrombin-stimulated human platelets. (1988) (37)
- Amiloride and analogues inhibit Na(+)-H+ exchange and cell proliferation in AR42J pancreatic cell line. (1990) (37)
- Amiloride and amiloride analogs inhibit Na+/K+-transporting ATPase and Na+-coupled alanine transport in rat hepatocytes. (1988) (37)
- Endothelin stimulates Na(+)-K(+)-ATPase activity by a protein kinase C-dependent pathway in rabbit aorta. (1991) (37)
- Effect of partial Na pump and Na-H exchange inhibition on [Ca]i during acidosis in cardiac cells. (1991) (37)
- Purification and subunit structure of the [3H]phenamil receptor associated with the renal apical Na+ channel. (1987) (36)
- The mechanism of action of amiloride. (1988) (36)
- Characteristics of the Na+-H+ antiporter in the intact renal proximal tubular cell. (1986) (36)
- Ultrastructural features of a brain injury model in cat (1988) (36)
- Activation of proximal tubular Na(+)-H+ exchange by angiotensin II. (1992) (36)
- Interaction of amiloride and its analogues with adenosine A1 receptors in calf brain. (1990) (36)
- Culture-induced alterations in alveolar type II cell Na+ conductance. (1993) (36)
- Successive inactivation of the force-generating units of sodium-driven bacterial flagellar motors by a photoreactive amiloride analog. (1994) (36)
- Na/H exchange-dependent cell volume and pH regulation and disturbances. (1988) (35)
- Regulation of pH in rat papillary tubule cells in primary culture. (1987) (35)
- [3H]ethylpropylamiloride, a radio‐labelled diuretic for the analysis of the Na+/H+ exchange system. Its use with kidney cell membranes. (1984) (35)
- 5-(N-ethyl-N-isopropyl)amiloride and mild acidosis protect cultured cerebellar granule cells against glutamate-induced delayed neuronal death (1992) (35)
- Synergistic alpha-1 and alpha-2 adrenergic stimulation of rat proximal nephron Na+/H+ exchange. (1989) (34)
- IGF-I regulation of Na(+)-K(+)-ATPase in rat arterial smooth muscle. (1997) (34)
- Inhibition of colonic Na+ transport by amiloride analogues. (1989) (34)
- Identification of amiloride-sensitive Na+/H+ exchange in rat NB2 node lymphoma cells. Stimulation by 12-O-tetradecanoyl-phorbol-13-acetate. (1987) (34)
- Cell volume regulation in human neutrophils: 2-(aminomethyl)phenols as Cl- channel inhibitors. (1993) (34)
- Activation of the Na+/H+ antiport is not required for lectin-induced proliferation of human T lymphocytes. (1986) (34)
- Extracellular ATP stimulates an amiloride-sensitive sodium influx in human lymphocytes. (1990) (34)
- Demonstration of a Na+/H+ exchange activity in purified canine cardiac sarcolemmal vesicles. (1985) (33)
- Inhibition of Na/H exchange in avian intestine by atrial natriuretic factor. (1990) (33)
- Ursodeoxycholic acid choleresis: relationship to biliary HCO-3 and effects of Na+-H+ exchange inhibitors. (1988) (32)
- Arginine vasopressin stimulates net fluid secretion in a polarized subculture of cyst-forming MDCK cells. (1991) (32)
- Protein kinase C-mediated intracellular alkalinization in rat and rabbit aortic smooth muscle cells. (1987) (31)
- Effects of amiloride on isolated Malpighian tubules of the yellow fever mosquito (Aedes aegypti) (1992) (31)
- Enhancement of ricin cytotoxicity in Chinese hamster ovary cells by depletion of intracellular K+: evidence for an Na+/H+ exchange system in Chinese hamster ovary cells (1985) (31)
- Characterization of the mitochondrial Na+H+ exchange. The effect of amiloride analogues (1988) (30)
- Involvement of calcium and protein kinase C in the activation of the Na+/H+ exchanger in cultured bovine aortic endothelial cells stimulated by extracellular ATP. (1989) (30)
- Na+/H+ exchange modulates the production of leukotriene B4 by human neutrophils. (1989) (30)
- Taurine indirectly increases [Ca]i by inducing Ca2+ influx through the Na+-Ca2+ exchanger (1998) (30)
- Intracellular pH in Human Resistance Arteries in Essential Hypertension (1991) (29)
- Studies on L‐640,035: a novel antagonist of contractile prostanoids in the lung (1984) (29)
- Phenamil: An irreversible inhibitor of sodium channels in the toad urinary bladder (2005) (29)
- Multiple receptors linked to inhibition of adenylate cyclase accelerate Na+/H+ exchange in neuroblastoma x glioma cells via a mechanism other than decreased cAMP accumulation. (1987) (29)
- Intracellular pH in vascular smooth muscle: regulation by sodium-hydrogen exchange and multiple sodium dependent HCO3- mechanisms. (1995) (29)
- Low-dose glucocorticoids stimulate electroneutral NaCl absorption in rat colon. (1989) (29)
- Photolabeling of tonoplast from sugar beet cell suspensions by [h]5-(N-methyl-N-isobutyl)-amiloride, an inhibitor of the vacuolar na/h antiport. (1990) (28)
- Amiloride-sensitive Na+/H+ exchange in rat NB2 node lymphoma cells. Stimulation by prolactin and other mitogens. (1987) (28)
- New amiloride analogue as hapten to raise anti-amiloride antibodies. (1986) (28)
- [3H]phenamil, a radiolabelled diuretic for the analysis of the amiloride-sensitive Na+ channels in kidney membranes. (1986) (28)
- HCl-induced cell edema in rabbit esophageal epithelium: a bumetanide-sensitive process. (1995) (28)
- Atrial natriuretic peptide and cGMP inhibit Na+/H+ antiporter in vascular smooth muscle cells in culture. (1994) (28)
- Relationship among activation of the Na+/H+ antiporter, ornithine decarboxylase induction, and DNA synthesis. (1987) (28)
- Calcium dependency of frequency-stimulated atrial natriuretic peptide secretion. (1994) (28)
- Effects of amiloride analogues on Na+ transport in toad bladder membrane vesicles. Evidence for two electrogenic transporters with different affinities toward pyrazinecarboxamides. (1987) (28)
- Single-cell analysis of the intracellular pH and its regulation during the monocytic differentiation of U937 human leukemic cells. (1988) (28)
- Sodium-Lithium Exchange and Sodium-Proton Exchange Are Mediated by the Same Transport System in Sarcolemmal Vesicles From Bovine Superior Mesenteric Artery (1989) (28)
- The effect of amiloride analogs on taste responses in gerbil (1990) (28)
- Thermosensitization by increasing intracellular acidity with amiloride and its analogs. (1994) (27)
- Ion transport mechanisms in rat parotid intralobular striated ducts. (1994) (27)
- Actions of bradykinin and related peptides on rabbit coeliac artery rings (1989) (27)
- Control of hepatocyte DNA synthesis by intracellular pH and its role in the action of tumor promoters (2003) (27)
- Na(+)-H+ exchange is not important for pancreatic HCO3- secretion in the pig. (1992) (26)
- Effects of barium and 5-(N-ethyl-N-isopropyl)-amiloride on proximal tubule ammonia transport. (1992) (26)
- Monovalent cation and amiloride analog modulation of adrenergic ligand binding to the unglycosylated alpha 2B-adrenergic receptor subtype. (1991) (26)
- Intracellular [Na+], Na+ pathways, and fluid transport in cultured bovine corneal endothelial cells. (2004) (26)
- Effects of HMA, an analog of amiloride, on the thermosensitivity of tumors in vivo. (1994) (25)
- Na(+)-Ca2+ exchange activity in central nerve endings. II. Relationship between pharmacological blockade by amiloride analogues and dopamine release from tuberoinfundibular hypothalamic neurons. (1990) (25)
- Electrogenic sodium absorption in rabbit cecum in vitro. (1988) (25)
- Intracellular pH and cell adhesion to solid substrate (1988) (24)
- Effects of 5-(N, N Hexamethylene) Amiloride on Action Potentials, Intracellular Na, and pH of Guinea Pig Ventricular Muscle In Vitro (1994) (24)
- Interactions of chloride and amiloride with the renal Na+/H/ antiporter. (1988) (24)
- Na+ influx is mediated by Na(+)-K(+)-2Cl- cotransport and Na(+)-H+ exchange in sublingual mucous acini. (1993) (24)
- Evidence of alpha 1-adrenergic----protein kinase C----Na+/H+ antiporter-dependent increase in pinealocyte intracellular pH. Role in the adrenergic stimulation of cGMP accumulation. (1989) (24)
- Effects of serotonin on intracellular pH and contraction in vascular smooth muscle. (1992) (23)
- Conductive sodium pathway with low affinity to amiloride in LLC-PK1 cells and other epithelia. (1988) (23)
- Sodium-calcium exchanger in cultured human retinal pigment epithelium. (1997) (23)
- Properties of the Na+-dependent Cl-/HCO3- exchange system in U937 human leukemic cells. (1987) (23)
- Delineation of the role of a Na+/Ca2+ exchanger in regulating intracellular Ca2+ in T cells. (1993) (23)
- Regulation of cytoplasmic pH of cultured bovine corneal endothelial cells in the absence and presence of bicarbonate (1988) (23)
- Effects of amiloride and its analogues on [3H]batrachotoxinin-A 20-alpha benzoate binding, [3H]tetracaine binding and 22Na influx. (1988) (23)
- Methyl isobutyl amiloride: a new probe to assess the number of Na-H antiporters. (1989) (22)
- Modulation of bovine aortic alpha-2 receptors by Na+, 5'-guanylylimidodiphosphate, amiloride and ethylisopropylamiloride: evidence for receptor G-protein precoupling. (1990) (22)
- Species‐specific Mn2+/Mg2+ antiport from Mg2+‐loaded erythrocytes (1990) (22)
- Sodium Channel Blockers Are Vasodilator As Well As Natriuretic and Diuretic Agents (1985) (22)
- Amiloride and 5-(N-ethyl-N-isopropyl) amiloride inhibit medium acidification and glucose metabolism by the fission yeast Schizosaccharomyces pombe. (1993) (22)
- IP3-and cAMP-induced responses in isolated olfactory receptor neurons from the channel catfish (1992) (21)
- Identification and purification of a renal amiloride-binding protein with properties of the Na+-H+ exchanger. (1989) (20)
- Na+ transport in human proximal colonic apical membrane vesicles. (1994) (20)
- Ouabain. A stimulator of atrial natriuretic peptide secretion and its mechanism of action. (1993) (20)
- Recombinant human interleukin 1-stimulated Na+/H+ exchange is not required for differentiation in pre-B lymphocyte cell line, 70Z/3. (1987) (20)
- Brain anti-cytoxic edema agents. (1990) (20)
- Different development of apical and basolateral Na-H exchangers in LLC-PK1 renal epithelial cells: characterization by inhibitors and antisense oligonucleotide. (1994) (20)
- Influence of atrial natriuretic factor on 5-(N-ethyl-N-isopropyl)amiloride-sensitive 22Na+ uptake in rabbit aorta. (1989) (20)
- Regulation of cytoplasmic pH in rat sublingual mucous acini at rest and during muscarinic stimulation (1992) (20)
- Glucocorticoids inhibit colonic aldosterone-induced conductive Na+ absorption in adrenalectomized rat. (1992) (20)
- Alpha 2-adrenergic receptors regulate Na(+)-H+ exchange via a cAMP-dependent mechanism. (1990) (19)
- Inhibition of Na+ influx and DNA synthesis in human fibroblasts and neuroblastoma-glioma hybrid cells by amiloride analogs. (1983) (19)
- Volume‐dependent K+ and Cl‐ fluxes in rat thymocytes. (1993) (19)
- HCO3(-)-dependent intracellular pH regulation in the premature myocardium. (1992) (19)
- Cytoplasmic pH change induced by leukotriene B4 in human neutrophils. (1988) (19)
- Na+-H+ and Na+-Ca2+ exchange in glomerulosa cells: possible role in control of aldosterone production. (1988) (19)
- Regulation of amino acid uptake by phorbol esters and hypertonic solutions in rat thymocytes (1986) (19)
- Conductive cation transport in apical membrane vesicles prepared from fetal lung. (1994) (19)
- Intracellular pH and Catecholamine Secretion from Bovine Adrenal Chromaffin Cells (1991) (19)
- The role of transmembrane cationic gradients in immune complex stimulation of human polymorphonuclear leukocytes (1988) (19)
- The Role of the Na+/H+ Antiporter in Human Neutrophil NADPH‐Oxidase Activation (1988) (18)
- Effects of pHi on Na(+)-H+, Na(+)-dependent, and Na(+)-independent C1(-)-HCO3-exchangers in vascular smooth muscle. (1991) (18)
- Sodium‐Lithium Exchange in Sarcolemmal Vesicles From Canine Superior Mesenteric Artery (1988) (18)
- Agonist-specific role for Na+-H+ antiport in prostaglandin release from microvessel endothelium. (1989) (18)
- Inhibition by 5-N-(4-chlorobenzyl)-2',4'-dimethylbenzamil of Na+/Ca2+ exchange and L-type Ca2+ channels in isolated cardiomyocytes. (1997) (18)
- Inhibition of taste responses to Na+ salts by epithelial Na+ channel blockers in gerbil (1990) (18)
- Effect of Na+/H+ exchange inhibitors on agonist-induced contraction of rat aorta. (1988) (17)
- Chloride conductance of apical membrane in cultured porcine thyroid cells activated by cyclic AMP (1992) (17)
- Characterization of the mitochondrial Na+-H+ exchange. The effect of amiloride analogues. (1988) (17)
- Modulation of intracellular pH by secretagogues and the Na+/H+ antiporter in cultured bovine chromaffin cells (1991) (17)
- Vascular effects of tetramethylpyrazuie: direct interaction with smooth muscle α-adrenoceptors (1991) (17)
- Polyvalent cations inhibit human neutrophil chemotaxis by interfering with the polymerization of actin. (1990) (17)
- Receptor binding profiles of amiloride analogues provide no evidence for a link between receptors and the Na+/H+ exchanger, but indicate a common structure on receptor proteins. (1991) (16)
- Na+-dependent activation of Na+-K+ pump in human myocardium during recovery from acidosis. (1989) (16)
- Stimulation of Na+/H+ exchange is not required for induction of hypertrophy of renal cells in vitro. (1992) (16)
- Mechanisms of Na+ transport in human distal colonic apical membrane vesicles. (1994) (16)
- Na+ dependence of gonadotropin-releasing hormone action: characterization of the Na+/H+ antiport in pituitary gonadotropes. (1991) (16)
- Intracellular accumulation of potent amiloride analogues by human neutrophils. (1987) (16)
- Volume regulation determinants in isolated proximal tubules in hypertonic medium. (1989) (15)
- Evidence for a DIOA-sensitive [K+,Cl-]-cotransport system in cultured vascular smooth muscle cells. (1990) (15)
- The hydrophobic tryptic core of the porcine alpha 2-adrenergic receptor retains allosteric modulation of binding by Na+, H+, and 5-amino-substituted amiloride analogs. (1990) (15)
- Alpha-adrenoceptors in vascular smooth muscle: all is not well. (1991) (15)
- Leukotriene D4-induced proliferation of glomerular epithelial cells: PKC- and Na+-H+ exchanger-mediated response. (1989) (14)
- Inner medullary collecting duct Na(+)-H+ exchanger. (1991) (14)
- The influence of calcium, sodium, and the Na+/Ca2+ antiport on susceptibility to cytolysin/perforin-mediated cytolysis. (1990) (14)
- Endothelin-induced contraction of human peripheral resistance vessels is partly dependent on stimulation of sodium-hydrogen exchange. (1989) (14)
- Stimulation of Ca2+ uptake into epididymal bull spermatozoa by analogues of amiloride. (1990) (14)
- The effect of sodium transport and calcium channel inhibitors on phorbol ester-induced contraction of bovine airway smooth muscle. (1993) (14)
- Protection by benzamil against dysfunction and damage in rat myocardium after calcium depletion and repletion. (1990) (14)
- The Neuronal Basis of Salt Sensitivity (1989) (14)
- Inhibition of brain mitochondrial Ca2+ transport by amiloride analogues. (1985) (13)
- Regulation of thyroid follicular volume by bidirectional transepithelial ion transport (1991) (13)
- Inhibition of Na + / Ca 2 " exchange in membrane vesicle and papillary muscle preparations from guinea pig heart by analogs of amiloride ( calcium influx / intracellular calcium stores / contractility ) (13)
- Amiloride analogues induce responses in isolated rat cardiovascular tissues by inhibition of Na+/Ca2+ exchange (2004) (13)
- Na+/H+ exchange modulates rat neutrophil mediated tumor cytotoxicity. (1991) (13)
- Amiloride analogues inhibit proximal tubule metabolism. (1986) (13)
- Mechanism of chloride uptake in rabbit corneal epithelium. (1989) (13)
- Systemic blood acidosis in low-flow ischemia induces capillary luminal narrowing. (1994) (13)
- Characterization of an apical sodium conductance in rabbit cecum. (1993) (13)
- Intracellular pH in frog skin: effects of Na+, volume, and cAMP. (1988) (13)
- Effect of amiloride on the compensatory renal growth that follows uninephrectomy in mice. (1989) (13)
- Regulation of aldosterone biosynthesis by Na+/H+ antiport: relationships between intracellular pH and angiotensin II. (1989) (13)
- Solubilization and reconstitution of renal brush border Na+-H+ exchanger. (1988) (12)
- Solubilization and reconsitution of renal brush border Na+−H+ exchanger (2005) (12)
- The relationship between mitogen-induced changes in the cytoplasmic pH and free Ca2+ concentration in rat thymocytes. (1990) (12)
- The interaction of amiloride analogues with the Na+/H+ exchanger in kidney medulla microsomes. (1984) (12)
- Influence of isolation media on synaptosomal properties: Intracellular pH, pCa, and Ca2+ uptake (1990) (12)
- Possible involvement of Ca++ ions, protein kinase C and Na(+)-H+ antiporter in insulin-induced endogenous dopamine release from tuberoinfundibular neurons. (1990) (12)
- Secretin stimulates bile ductules to secrete both H+ and HCO3(-)-ions. (1992) (12)
- LLC-PK1 mutant with increased Na+-H+ exchange and decreased sensitivity to amiloride. (1988) (12)
- Inhibition by amiloride analogues of Na+-dependent hexose uptake in LLC-PK1/Cl4 cells. (1987) (12)
- A role for Na+/H+ exchange in contraction of guinea pig airways by endothelin-1 in vitro. (1991) (11)
- Structure-activity relations of amiloride derivatives, acting as antagonists of cation binding on Na+/K(+)-ATPase. (1993) (11)
- Calcium: its role in alpha 1-adrenergic stimulation of atrial natriuretic peptide secretion. (1992) (11)
- Amiloride derivatives that block Na+/Ca2+ exchange inhibit spontaneous inward currents in Na+-loaded cardiac myocytes. (1987) (11)
- A dextran-bound amiloride derivative is a selective inhibitor of Na+/H+ antiport. Application for studying the role of the antiporter in cellular proliferation in human fibroblasts. (1987) (11)
- Intracellular acidification-induced alkali metal cation/H+ exchange in human neutrophils (1987) (10)
- Alpha 2-adrenergic receptor-mediated regulation of intestinal calcium transport. (1985) (10)
- Mechanism of hyperosmolality stimulation of ANP secretion: its dependency on calcium and sodium. (1995) (10)
- The significance of the relative effects of loop diuretics and anti-brain edema agents on the Na+, K+, Cl− cotransport system and the Cl−/NaCO3− anion exchanger (1986) (10)
- Bidirectional ion transport in thyroid: secretion of anions by monolayer cultures that absorb sodium. (1992) (10)
- High affinity binding of amiloride analogs at an internal site in renal microvillus membrane vesicles. (1991) (10)
- Evidence for a Role for Na+‐H+ Exchange in Activation of Human Platelets by PAF (1987) (10)
- Novel amiloride analog allosterically modulates the alpha 2-adrenergic receptor but does not inhibit Na+/H+ exchange. (1992) (10)
- DNA intercalation and inhibition of topoisomerase II. Structure-activity relationships for a series of amiloride analogs. (1989) (10)
- Kinetic properties of the Na+/H+ antiport of heart mitochondria. (1989) (10)
- Na+-Ca2+ exchange and calcium permeability in canine basolateral membrane vesicles: the effects of dibutyryl cAMP and specific inhibitors. (1988) (10)
- The intracellular localization of amiloride in frog skin (1983) (10)
- The Na+/Ca2+ exchanger regulates cytolysin/perforin-induced increases in intracellular Ca2+ and susceptibility to cytolysis. (1992) (9)
- Antagonistic effect of amiloride on alpha-2 adrenoceptor-mediated pigment aggregation: pharmacological heterogeneity between B-HT 920 and noradrenaline. (1991) (9)
- An epithelial high-affinity amiloride-binding site, different from the Na+ channel. (1993) (9)
- Characterization of chicken intestinal brush border membrane Na/H exchange. (1992) (9)
- Sequential sodium-proton exchange in thrombin-induced human platelets. (1987) (9)
- Modulation of kidney cell protein degradation by insulin. (1990) (9)
- The Na+/H+ antiport in renal mitochondria. (1995) (9)
- Determinants of ammonia entry along the rat proximal tubule during chronic metabolic acidosis. (1989) (9)
- Inhibitory effect of local anesthetics on Na+/H+ antiporter in brush border membrane-reconstituted vesicles. (1990) (8)
- Inhibition of Na/Ca exchange in pancreatic islet cells by 3',4'-dichlorobenzamil. (1991) (8)
- Ion transport in rabbit proximal colon: effects of sodium, amiloride, cAMP, and epinephrine. (1994) (8)
- Effect of 6-iodoamiloride in various models of experimental hypertension. (1988) (8)
- Characterization of Na+-dependent and Na+-independent Mg2+ efflux from erythrocytes by amiloride derivatives (1989) (8)
- Role of sodium in mediator release from human basophils. (1992) (8)
- Inhibition of monoamine oxidase by analogues of amiloride. (1989) (8)
- Intracellular pH in rat resistance arteries during the development of experimental hypertension. (1991) (8)
- Structure-activity relationship of amiloride analogs as blockers of epithelial Na channels: II. Side-chain modifications (2005) (8)
- Mechanisms of regulatory volume increase in collecting duct cells. (1993) (7)
- Leukotriene D4‐induced increases in the cytoplasmic pH of human myelocytic leukocytes (1988) (7)
- Regulation of Intracellular pH in Human Platelets (2001) (7)
- Distinct epitopes on amiloride. (1989) (7)
- pH in principal cells of frog skin (Rana pipiens): dependence on extracellular Na+. (1988) (7)
- High-performance liquid chromatographic determination of amiloride and its analogues in rat plasma. (1990) (7)
- Inhibitory effects of amilorides on pinealocyte adenosine 3',5'-monophosphate and guanosine 3',5'-monophosphate accumulation: possible involvement of postreceptor mechanisms. (1990) (7)
- Expression of a mammalian Na–H exchanger in muscle fibres of the giant barnacle (1985) (7)
- Effects of amiloride and an analogue on ventricular arrhythmias, contracture and cellular injury during reperfusion in isolated and perfused guinea pig heart. (1991) (7)
- Phenamil inhibits electrogenic sodium absorption in rabbit ileum. (1989) (7)
- Low-dose glucocorticoids maintain Na-H exchange in distal colon of adrenalectomized rats. (1991) (7)
- The mode of interaction of amiloride and some of its analogues with the adenosine A1 receptor (1992) (7)
- Influence of amiloride derivatives on alpha-1 adrenergic receptor-induced contractions of the rabbit aorta. (1990) (6)
- Activation of sodium transport mediates regulation of thyroid follicle volume in response to hypotonic media. (1993) (6)
- Comparison with the Muscarinic Agonist Carbachol (1990) (6)
- Control of ion transport in the thyroid: prostaglandin E2 activates cation transport on the basal membrane of cultured porcine thyroid cell monolayers. (1990) (6)
- Preparation of 6-125I-labeled amiloride derivatives. (1988) (6)
- Cytoplasmic alkalinization induced by insulin through an activation of Na(+)-H+ antiporter inhibits tyrosine hydroxylase activity in striatal synaptosomes. (1991) (6)
- Pyrazine compounds and the measurement of cytosolic Ca2+. (1993) (6)
- N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline, amiloride analogues, and renal Na+/H+ antiporter. (1987) (6)
- Amiloride analogs induce the phosphorylation of elongation factor-2 in vascular endothelial cells. (1990) (6)
- Treatment of tyramine-induced brain edema with anion transport inhibitor L-644,711. (1988) (5)
- The depressant effects of some amiloride analogues on the slow outward K+ current and contraction of voltage-clamped frog muscle fibres. (1989) (5)
- Effects of amiloride and 5-(N,N-hexamethylene)amiloride on dopaminergic and cholinergic neurotransmission. (1988) (5)
- Comparison of the effectiveness of seven amiloride congeners as inhibitors of Na/H and Na/Ca antiport in cultured smooth muscle cells (1987) (5)
- Study of fibroblast spreading: pH dependence, involvement of the Na+/H(+)-antiporter and PKC. (1993) (5)
- Vascular effects of tetramethylpyrazine: direct interaction with smooth muscle alpha-adrenoceptors. (1991) (5)
- Inhibitory effects of amiloride and its analogues on prostaglandin E2-stimulated fluid transport by cultured porcine thyroid cells: evidence for apical membrane Na+ channels. (1989) (4)
- Regulation of the Na+/H+ antiporter: evidence for a membrane shuttling mechanism. (1993) (4)
- Cytosolic pH changes in contracting canine trachealis smooth muscle. (1990) (4)
- Direct inhibition of contractile apparatus by analogues of amiloride in the smooth muscle of guinea-pig taenia caecum and chicken gizzard. (1989) (4)
- Volume- and catecholamine-dependent regulation of Na/H antiporter and unidirectional potassium fluxes in Salmo trutta red blood cells (1994) (4)
- Paradoxical effects of amiloride analogs on protein phosphorylation and serotonin release induced by agonists in human platelets. (1988) (4)
- Wound currents and wound healing in the newt, Notophthalmus viridescens (1990) (4)
- Heterogeneity of the Na(+)-H+ antiport systems in renal cells. (1992) (4)
- Evidence for the O-sulfo derivative of MK-447 as active metabolite of MK-447. (1991) (4)
- Role of sodium in antigen-induced contraction of tracheal smooth muscle in dogs. (1993) (4)
- Hyponatremia-induced brain edema in guinea pigs is reduced by treatment with the novel anion transport inhibitor L-644,711. (1989) (3)
- 5-(N,N-dimethyl)amiloride-sensitive Na-Li exchange in isolated specimens of human atrium. (1988) (3)
- LLC-PK sub 1 mutant with increased Na sup + -H sup + exchange and decreased sensitivity to amiloride (1988) (3)
- Effect of ethylisopropyl amiloride on intracellular pH regulation in cultured rat astrocytes. (1989) (3)
- Effects of Na+/H+ exchange inhibition on cardiac reperfusion arrhythmias (1988) (3)
- Characterization of Na/sup +/-linked and Na/sup +/-independent Cl/sup -//HCO/sub 3//sup -/ exchange systems in Chinese hamster lung fibroblasts (1988) (3)
- Na+/H+ exchange in PAF-stimulated platelets. (1989) (3)
- Development of reversible and irreversible inhibitors of Na+/Ca2+ exchange in pituitary plasma membrane vesicles. (1984) (3)
- Rapid Communication: Exaggerated Depressor Response to 6-lodoamiloride in NaCl-Sensitive Spontaneously Hypertensive Rats (1988) (2)
- Ursodeoxycholic acid choleresis: Relationship to biliary HCO sup minus sub 3 and effects of Na sup + -H sup + exchange inhibitors (1988) (2)
- Evidence for a Na+/H+ exchanger at the basolateral membranes of the isolated frog skin epithelium: Effect of amiloride analogues (1987) (2)
- Binding of3H-phenamil, an irreversible amiloride analog, to toad urinary bladder: effects of aldosterone and vasopressin (2005) (2)
- Sodium–Proton (Na+/H+) Exchange Inhibition Increases Blood Pressure in Spontaneously Hypertensive Rat (1994) (2)
- A Study of the Interaction between the Na+, K+ Pump and Na+ : Ca 2+ Exchange in Macrophages and Vascular Smooth Muscle Cells (1988) (2)
- Electrogenic sodium transport in the developing rabbit cecum. (1989) (2)
- Inhibition of Na+ flux in Chinese hamster ovary cells and Swiss 3T3 cells by a potent new derivative of amiloride, methylisopropyl-amiloride. (1986) (2)
- Determination of active 5-(N,N-hexamethylene)amiloride in pig plasma. (1992) (2)
- Amiloride analogs stimulate protein phosphorylation and serotonin release in human platelets. (1988) (1)
- Mechanisms influencing sodium entry to cultured vascular smooth muscle. (1988) (1)
- Characteristics of Two Different Na+‐H+ Antiport Systems in Several Epithelial and Nonepithelial Cell Lines (1989) (1)
- Effects of anion exchange on intracellular pH and tension in basilar artery of dogs. (1996) (1)
- Identification of apical membranes from tight epithelia using spin-labeled amiloride and electron paramagnetic resonance spectroscopy (2005) (1)
- Effects of epidermal growth factor on gluconeogenesis and cellular redox state do not require Na+/H+ exchange or Na+/K+-ATPase activities (1994) (1)
- Effect of autologous serum on human leucocyte Na+/H+ exchange and intracellular pH. (1990) (1)
- Na-H Exchange Is a Major Determinant of Cellular Sodium Handling in Vascular Smooth-Muscle Cells (1986) (1)
- [The role of ion transport system of sarcolemma in amino acid loss during myocardial perfusion with calcium-free medium and myocardium injury during "calcium paradox"]. (1999) (1)
- An aldosterone regulated chicken intestine protein with high affinity to amiloride. (1997) (1)
- Effects of 6-iodo-amiloride, a sodium channel blocker, on cardiovascular parameters in spontaneously hypertensive and Wistar-Kyoto rats. (1986) (1)
- Actions ofamiloride analogues onprostacyclin synthesis byrataortic rings (1987) (1)
- Inhibition of bradykinin-induced increases of cytosolic Ca++ by a novel amiloride analog. (1989) (1)
- Intracellular pH and Contraction in Vascular Smooth Muscle (2005) (0)
- Regulation of Intracellular ph in Beating Mammalian Cardiac Cells (1988) (0)
- Inhibition by amiloride analogues of Na sup + -dependent hexose uptake in LLC-PK sub 1 /Cl sub 4 cells (1987) (0)
- [Effect of blockers of the sarcolemmal anion transporter systems on the development of myocardial edema during ischemia and recovery of the contractile function during reperfusion]. (1999) (0)
- [Effect of sarcolemmal ion-transporting system blockers on the intensity of heart damage during "calcium paradox"]. (2000) (0)
- [Mechanisms of action of hypersodium medium on contractile activity of isolated rat heart]. (2001) (0)
- 18 Blockade of the Na+/H+ antiport in resistance arterioles from spontaneously hypertensive and Wlstar‐Kyoto rats with amilorlde analogues: evidence of a central role in vascular contraction (1988) (0)
- Endothelin Stimulates Na/H Exchange in Human Peripheral Resistance Vessels but does not Inhibit Isolated Na/K ATPase (1989) (0)
- [The importance of the ion-transport systems of the sarcolemma and sarcoplasmic reticulum in changing rat cardiac contractile function under a hypersodium medium]. (1999) (0)
- Development of lnhibitory Ligands (1987) (0)
- Exaggerated depressor response to 6-iodoamiloride in NaCl-sensitive spontaneously hypertensive rats. (1988) (0)
- News of the Society for Microcirculation (1994) (0)
- A study of the interaction between the Na+, K+ pump and Na+:Ca2+ exchange in macrophages and vascular smooth muscle cells. (1988) (0)
- Angiotensin I1 Effect on Cytosolic pH in Cultured Rat Vascular Smooth Muscle Cells* (2001) (0)
- Hormonal and pharmacologic regulation of sodium absorption in rabbit cecumin vitro (1992) (0)
- Nordic Microcirculation Society (1994) (0)
- 5-(N,N-Hexamethylene) Amiloride is an Effective Inhibitor of Na/H Exchange in Human Leucocytes (1989) (0)
- MECHANISMS INVOLVED IN 5-HT STIMULATION OF PROSTACYCLIN PRODUCTION BY BOVINE AORTIC SMOOTH MUSCLE CELLS (1987) (0)
- Inhibition of Na/sup +/-dependent uptake of hexose and amino acids in LLC-PK1 cells by amiloride and amiloride-derivatives (1986) (0)
- Renal Effects of Selective Alpha-1 and Alpha-2 Adre noceptor Agonists in Conscious , Normotensive Rats (2017) (0)
- Amiloride inhibits the vasopressin-induced increase in epithelial water permeability (1990) (0)
- [Dependence of myocardial damage on the anion composition and osmotic pressure in the extracellular fluid during "calcium paradox" in rats]. (1999) (0)
- [The mechanisms of the effect of a high extracellular sodium concentration on the contractile activity of the isolated rat heart]. (1996) (0)
- Mechanisms influencing Na+ entry in cultured vascular smooth muscle (1988) (0)
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What Schools Are Affiliated With E. J. Jr. Merck Sharp Cragoe?
E. J. Jr. Merck Sharp Cragoe is affiliated with the following schools:
- Vanderbilt University
- Nagoya University
- University of Manitoba
- Temple University
- University of Rochester
- University of Pennsylvania
- University of Leicester
- University of Alabama
- Boston University
- New York Medical College
- University of Queensland
- Tufts University
- Louisiana State University
- Wayne State University
- University of Puerto Rico
- Semmelweis University
- Yale University
- Midwestern University
