Eva J. Neer
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Eva J. Neerbiology Degrees
Biology
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#14588
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Cell Biology
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#572
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Neuroscience
#1800
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#1856
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Biochemistry
#1830
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#1969
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Biology
Eva J. Neer's Degrees
- PhD Biochemistry Stanford University
- Bachelors Biology University of California, Berkeley
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Why Is Eva J. Neer Influential?
(Suggest an Edit or Addition)Eva J. Neer's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Heterotrimeric C proteins: Organizers of transmembrane signals (1995) (1470)
- The ancient regulatory-protein family of WD-repeat proteins (1994) (1250)
- The WD repeat: a common architecture for diverse functions. (1999) (1239)
- The βγ subunits of GTP-binding proteins activate the muscarinic K+ channel in heart (1987) (1071)
- G protein beta gamma subunits. (1997) (827)
- Roles of G protein subunits in transmembrane signalling (1988) (724)
- New roles for G-protein (βγ-dimers in transmembrane signalling (1993) (594)
- Purification and properties of the inhibitory guanine nucleotide regulatory unit of brain adenylate cyclase. (1984) (417)
- G0 is a major growth cone protein subject to regulation by GAP-43 (1990) (394)
- G-protein βγ-subunits activate the cardiac muscarinic K+-channel via phospholipase A2 (1989) (364)
- The ancient regulatory-protein family of WD-repeat proteins (1994) (342)
- G PROTEIN SUBUNITS (1997) (283)
- Transient cardiac expression of constitutively active Galphaq leads to hypertrophy and dilated cardiomyopathy by calcineurin-dependent and independent pathways. (1998) (274)
- The beta gamma subunits of GTP-binding proteins activate the muscarinic K+ channel in heart. (1987) (224)
- G Protein Heterodimers: New Structures Propel New Questions (1996) (221)
- Folding of proteins with WD-repeats: comparison of six members of the WD-repeat superfamily to the G protein beta subunit. (1996) (195)
- Specificity of G protein beta and gamma subunit interactions. (1992) (171)
- Physical and immunological characterization of a guanine nucleotide-binding protein purified from bovine cerebral cortex. (1985) (152)
- Go, a guanine nucleotide-binding protein: immunohistochemical localization in rat brain resembles distribution of second messenger systems. (1986) (150)
- Gαo is necessary for muscarinic regulation of Ca2+ channels in mouse heart (1997) (140)
- Specificity of action of guanine nucleotide-binding regulatory protein subunits on the cardiac muscarinic K+ channel. (1988) (133)
- Calmodulin activates the isolated catalytic unit of brain adenylate cyclase. (1981) (130)
- G proteins: Critical control points for transmembrane signals (1994) (128)
- Atrial natriuretic factor gene expression in ventricles of rats with spontaneous biventricular hypertrophy. (1988) (119)
- Sites for Gα Binding on the G Protein β Subunit Overlap with Sites for Regulation of Phospholipase Cβ and Adenylyl Cyclase* (1998) (115)
- Reconstitution of a hormone-sensitive adenylate cyclase system. The pure beta-adrenergic receptor and guanine nucleotide regulatory protein confer hormone responsiveness on the resolved catalytic unit. (1984) (102)
- Properties of the adenylate cyclase catalytic unit from caudate nucleus. (1983) (96)
- Sites Important for PLCβ2 Activation by the G Protein βγ Subunit Map to the Sides of the β Propeller Structure* (1998) (90)
- New roles for G-protein beta gamma-dimers in transmembrane signalling. (1993) (83)
- Embryonic stem cells lacking a functional inhibitory G-protein subunit (alpha i2) produced by gene targeting of both alleles. (1991) (83)
- Reactive sulfhydryl groups of alpha 39, a guanine nucleotide-binding protein from brain. Location and function. (1987) (83)
- In vitro synthesis of G protein beta gamma dimers. (1991) (81)
- Characterization by two-dimensional peptide mapping of the gamma subunits of Ns and Ni, the regulatory proteins of adenylyl cyclase, and of transducin, the guanine nucleotide-binding protein of rod outer segments of the eye. (1985) (80)
- Properties of the separated catalytic and regulatory units of brain adenylate cyclase. (1980) (78)
- The amino terminus of G protein alpha subunits is required for interaction with beta gamma. (1988) (77)
- Subunit interactions of native and ADP-ribosylated alpha 39 and alpha 41, two guanine nucleotide-binding proteins from bovine cerebral cortex. (1986) (77)
- Cardiac myocytes express mRNA for ten RGS proteins: changes in RGS mRNA expression in ventricular myocytes and cultured atria (1998) (75)
- Physical and functional properties of adenylate cyclase from mature rat testis. (1978) (74)
- G-protein alpha o subunit: mutation of conserved cysteines identifies a subunit contact surface and alters GDP affinity. (1993) (71)
- The size of adenylate cyclase. (1974) (70)
- Mutagenesis of the amino terminus of the alpha subunit of the G protein Go. In vitro characterization of alpha o beta gamma interactions. (1992) (67)
- Altered regulation of potassium and calcium channels by GABA(B) and adenosine receptors in hippocampal neurons from mice lacking Galpha(o). (2000) (65)
- Development of muscarinic cholinergic inhibition of adenylate cyclase in embryonic chick heart. Its relationship to changes in the inhibitory guanine nucleotide regulatory protein. (1986) (59)
- G alpha(o) is necessary for muscarinic regulation of Ca2+ channels in mouse heart. (1997) (58)
- The G protein gamma subunit. Requirements for dimerization with beta subunits. (1995) (55)
- Impaired parasympathetic heart rate control in mice with a reduction of functional G protein βγ-subunits (2002) (47)
- A 14-amino acid region of the G protein gamma subunit is sufficient to confer selectivity of gamma binding to the beta subunit. (1994) (45)
- Signal transduction in atria and ventricles of mice with transient cardiac expression of activated G protein alpha(q). (1999) (45)
- Identification of cDNA encoding an additional alpha subunit of a human GTP-binding protein: expression of three alpha i subtypes in human tissues and cell lines. (1988) (45)
- Promotion of the GTP-liganded state of the Go alpha protein by deletion of the C terminus. (1992) (44)
- Analysis of the physical properties and molecular modeling of Sec13: A WD repeat protein involved in vesicular traffic. (1996) (43)
- Dilated cardiomyopathy in two transgenic mouse lines expressing activated G protein alpha(q): lack of correlation between phospholipase C activation and the phenotype. (2001) (43)
- Evidence for uncoupling of the beta receptor-adenylate cyclase complex. (1980) (41)
- Interaction of soluble brain adenylate cyclase with manganese. (1979) (41)
- Structural and functional studies of cross-linked Go protein subunits. (1991) (40)
- A groovy new structure. (2000) (39)
- Size and detergent binding of adenylate cyclase from bovine cerebral cortex. (1978) (37)
- G-protein beta gamma-subunits activate the cardiac muscarinic K+-channel via phospholipase A2. (1989) (37)
- Interactions between the amino- and carboxyl-terminal regions of G alpha subunits: analysis of mutated G alpha o/G alpha i2 chimeras. (1995) (37)
- Reassembly of phospholipase C-beta2 from separated domains: analysis of basal and G protein-stimulated activities. (2001) (36)
- Signal transduction through G proteins in the cardiac myocyte. (1992) (35)
- Neuronal expression of a newly identified Drosophila melanogaster G protein alpha 0 subunit. (1989) (34)
- Intracellular signalling: Turning down G-protein signals (1997) (32)
- Vasopressin-responsive, soluble adenylate cyclase from the rat renal medulla. (1973) (31)
- G protein beta gamma subunit: physical and chemical characterization. (1993) (31)
- Molecular cloning and characterization of cDNA encoding the GTP-binding protein alpha i and identification of a related protein, alpha h. (1986) (31)
- Reconstituted adenylate cyclase from bovine brain. Functions of the subunits. (1981) (30)
- Conformations of the alpha 39, alpha 41, and beta.gamma components of brain guanine nucleotide-binding proteins. Analysis by limited proteolysis. (1986) (30)
- The Interactions between α and β Chains of Human Hemoglobin (1968) (29)
- Nerve growth factor changes G protein levels and localization in PC12 cells (1993) (28)
- LIS is more (1993) (27)
- Increase in the size of soluble brain adenylate cyclase with activation by guanosine 5'-(beta, gamma-imino)triphosphate. (1980) (27)
- Guanylate cyclase from the rat renal medulla. Physical properties and comparison with adenylate cyclase. (1975) (26)
- The vasopressin-sensitive adenylate cyclase of the rat renal medulla. (1973) (25)
- Impaired parasympathetic heart rate control in mice with a reduction of functional G protein betagamma-subunits. (2002) (25)
- The stimulatory guanine-nucleotide regulatory unit of adenylate cyclase from bovine cerebral cortex. ADP-ribosylation and purification. (1987) (23)
- Intersubunit surfaces in G protein alpha beta gamma heterotrimers. Analysis by cross-linking and mutagenesis of beta gamma. (1996) (22)
- Non-co-ordinate development of beta-adrenergic receptors and adenylate cyclase in chick heart. (1982) (21)
- Analysis of G-protein alpha and beta gamma subunits by in vitro translation. (1994) (21)
- Localization of G alpha 0 to growth cones in PC12 cells: role of G alpha 0 association with receptors and G beta gamma. (1996) (19)
- Expression of a G protein subunit, alpha i-1, in Balb/c 3T3 cells leads to agonist-specific changes in growth regulation. (1991) (19)
- Partial purification and characterization of a pp60v-src-related tyrosine kinase from bovine brain. (1985) (18)
- Differential degradation rates of the G protein alpha o in cultured cardiac and pituitary cells. (1990) (17)
- GTPases in Biology II (1993) (17)
- Subtype‐specific increase in G‐protein α‐subunit mRNA by interleukin 1β (1989) (17)
- The G Protein αo Subunit Alters Morphology, Growth Kinetics, and Phospholipid Metabolism of Somatic Cells (1989) (16)
- Maintenance of cellular levels of G-proteins: different efficiencies of alpha s and alpha o synthesis in GH3 cells. (1996) (14)
- Effect of deletion of the major brain G‐protein α subunit (αo) on coordination of G‐protein subunits and on adenylyl cyclase activity (1998) (14)
- GO, a guanine nucleotide binding protein, is expressed during neurite extension in the embryonic mouse (1994) (14)
- The G Protein γ Subunit (1995) (14)
- Two soluble forms of guanosine 5'-(beta,gamma-imino)triphosphate and fluoride-activated adenylate cyclase. (1976) (14)
- Modification of adenylate cyclase structure and function by ammonium sulfate. (1981) (13)
- Sites important for PLCbeta2 activation by the G protein betagamma subunit map to the sides of the beta propeller structure. (1998) (13)
- Regional localization of the human G protein alpha i2 (GNAI2) gene: assignment to 3p21 and a related sequence (GNAI2L) to 12p12-p13. (1992) (13)
- Multiple forms of adenylate cyclase. (1978) (13)
- Separation of soluble adenylate and guanylate cyclases from the mature rat testis. (1979) (10)
- CHAPTER 3 – Structure and Function of G-Protein βγ Subunit (1990) (9)
- The size of adenylate cyclase and guanylate cyclase from the rat renal medulla. (1976) (9)
- The site of alpha-chymotryptic activation of pigeon erythrocyte adenylate cyclase. (1980) (9)
- The Reactions of the Sulfhydryl Groups of Human Hemoglobin β4 (1970) (9)
- Desensitization of Chick Embryo Ventricle to the Physiological and Biochemical Effects of Isoproterenol: Evidence for Uncoupling of the β Receptor‐Adenylate Cyclase Complex (1980) (9)
- Characterization of a mastoparan-stimulated nucleotidase from bovine brain. (1991) (8)
- The characterization of modified human hemoglobin. II. Reaction with 1-fluoro-2,4-dinitrobenzene. (1968) (8)
- Functions of G-protein subunits. (1988) (7)
- Interaction of forskolin with resolved adenylate cyclase components. (1984) (7)
- Localization of Gαo to growth cones in PC12 cells: role of Gαo association with receptors and Gβγ (1996) (7)
- Intersubunit Surfaces in G Protein Heterotrimers (1996) (5)
- Maintenance of cellular levels of G-proteins : different efficiencies of α s and α o synthesis in GH 3 cells (1996) (5)
- Regulation of alpha o expression by the 5'-flanking region of the alpha o gene. (1994) (5)
- Activation of atrial muscarinic-gated K+ channels by beta gamma-subunits of G proteins. (1988) (5)
- The Recombination of α and β Chains of Human Hemoglobin EFFECT OF SULFHYDRYL GROUP MODIFICATIONS (1970) (5)
- Structural and functional studies of the Go protein. (1990) (4)
- Effect of deletion of the major brain G-protein alpha subunit (alpha(o)) on coordination of G-protein subunits and on adenylyl cyclase activity. (1998) (4)
- The gene for the alpha i1 subunit of human guanine nucleotide binding protein maps near the cystic fibrosis locus. (1988) (4)
- Effect of Triton X-100 and Alamethicin on the susceptibility of brain adenylate cyclase to EGTA inhibition. (1981) (3)
- Detergent solubilizes the dissociated catalytic unit of testicular adenylate cyclase (1981) (2)
- Subtype-specific increase in G-protein alpha-subunit mRNA by interleukin 1 beta. (1989) (2)
- Reassembly of Phospholipase C-β2 from Separated Domains (2001) (2)
- Identification of a retinal protein in Drosophila with antibody to the α subunit of bovine brain Go protein (1991) (2)
- Guanine nucleotide-binding proteins involved in transmembrane signaling. (1986) (2)
- Characterization of cDNA and genomic DNA encoding the a subunit of a human GTP-binding protein Gi (1987) (1)
- The Characterization of Modified Human Hemoglobin (2003) (1)
- The interactions between alpha and beta chains of human hemoglobin. (1968) (1)
- 15 – Solubilization and Characterization of Adenylyl Cyclase: Approaches and Problems (1977) (1)
- Guanylate Cyclase from the Rat Renal Medulla (2002) (1)
- Intersubunit Surfaces in G Protein (cid:97)(cid:98)(cid:103) Heterotrimers ANALYSIS BY CROSS-LINKING AND MUTAGENESIS OF (cid:98)(cid:103) * (1995) (1)
- Genes for two homologous G-protein α subunits map to different human chromosomes (1987) (1)
- Biologically active ( 14 C) vasopressin. A new and simplified synthesis. (1973) (0)
- Analysis of G proteins in mammals and flies. (1990) (0)
- Active site specificity of the adenylate cyclase catalytic unit from bovine caudate nucleus. (1986) (0)
- The Gene for the ca Subunit of Human Guanine Nucleotide Binding Protein Maps near the Cystic Fibrosis Locus (2006) (0)
- Molecular cloning and characterization of cDNA encoding the GTP-binding protein ai and identification of a related protein, (Xh (0)
- Identification of a retinal protein in Drosophila with antibody to the alpha subunit of bovine brain G(o) protein. (1991) (0)
- The reactions of the sulfhydryl groups of human hemoglobin beta 4. (1970) (0)
- Studies of Solubilized Adenylate Cyclase (1982) (0)
- The G protein alpha o subunit alters morphology, growth kinetics, and phospholipid metabolism of somatic cells (1989) (0)
- The recombination of alpha and beta chains of human hemoglobin. Effect of sulfhydryl group modifications. (1970) (0)
- The Family of G Proteins (1990) (0)
- Subunit Interactions of Heterotrimeric G-Proteins (1993) (0)
- PAIR OF THEORETICAL MODELS FOR THE S. CEREVISIAE G PROTEIN HETEROTRIMER, BASED ON THE COORDINATES OF THE MAMMALIAN G PROTEIN (1998) (0)
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