Edward John Wherry III
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American immunologist
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Edward John Wherry IIIbiology Degrees
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Immunology
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#157
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Biology
Edward John Wherry III's Degrees
- PhD Immunology University of Pennsylvania
- Bachelors Biology University of California, San Diego
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Why Is Edward John Wherry III Influential?
(Suggest an Edit or Addition)According to Wikipedia, Edward John Wherry III is an American immunologist. He is the Richard and Barbara Schiffrin President's Distinguished Professor and department chair of Systems Pharmacology and Translational Therapeutics at the University of Pennsylvania. He is also the director of the Penn Institute for Immunology.
Edward John Wherry III's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Restoring function in exhausted CD8 T cells during chronic viral infection (2006) (3786)
- T cell exhaustion (2011) (3032)
- PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression (2006) (2659)
- Molecular and cellular insights into T cell exhaustion (2015) (2659)
- Lineage relationship and protective immunity of memory CD8 T cell subsets (2003) (2030)
- Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells (2003) (1957)
- Radiation and Dual Checkpoint Blockade Activates Non-Redundant Immune Mechanisms in Cancer (2015) (1835)
- Molecular signature of CD8+ T cell exhaustion during chronic viral infection. (2007) (1779)
- Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection (2009) (1676)
- Viral Persistence Alters CD8 T-Cell Immunodominance and Tissue Distribution and Results in Distinct Stages of Functional Impairment (2003) (1558)
- Exosomal PD-L1 Contributes to Immunosuppression and is Associated with anti-PD-1 Response (2018) (1427)
- The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection (2007) (1396)
- Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus (2011) (1252)
- Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin (2005) (1210)
- Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications (2020) (1111)
- T-cell invigoration to tumour burden ratio associated with anti-PD-1 response (2017) (1109)
- Effector and memory T-cell differentiation: implications for vaccine development. Nat Rev Immunol. (2002) (977)
- Vaccines: Effector and memory T-cell differentiation: implications for vaccine development (2002) (939)
- Memory CD8 T-Cell Differentiation during Viral Infection (2004) (929)
- Redefining Chronic Viral Infection (2009) (908)
- Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia (2018) (880)
- CD8 T Cell Exhaustion During Chronic Viral Infection and Cancer. (2019) (806)
- Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade (2016) (801)
- Commensal bacteria calibrate the activation threshold of innate antiviral immunity. (2012) (791)
- Overcoming T cell exhaustion in infection and cancer. (2015) (790)
- Interleukin 15 Is Required for Proliferative Renewal of Virus-specific Memory CD8 T Cells (2002) (751)
- Progenitor and Terminal Subsets of CD8+ T Cells Cooperate to Contain Chronic Viral Infection (2012) (705)
- Tumor Interferon Signaling Regulates a Multigenic Resistance Program to Immune Checkpoint Blockade (2016) (698)
- TOX transcriptionally and epigenetically programs CD8+ T cell exhaustion (2019) (677)
- Innate lymphoid cells regulate CD4+ T cell responses to intestinal commensal bacteria (2013) (630)
- Heterologous immunity provides a potent barrier to transplantation tolerance. (2003) (629)
- Heterogeneity and cell-fate decisions in effector and memory CD8+ T cell differentiation during viral infection. (2007) (615)
- Defining ‘T cell exhaustion’ (2019) (604)
- The epigenetic landscape of T cell exhaustion (2016) (603)
- Comprehensive mapping of immune perturbations associated with severe COVID-19 (2020) (570)
- Antigen-independent memory CD8 T cells do not develop during chronic viral infection. (2004) (558)
- Dynamic T cell migration program provides resident memory within intestinal epithelium (2010) (547)
- Cutting Edge: Tissue-Retentive Lung Memory CD4 T Cells Mediate Optimal Protection to Respiratory Virus Infection (2011) (537)
- Antigen-Independent Differentiation and Maintenance of Effector-like Resident Memory T Cells in Tissues (2012) (524)
- Bioenergetic Insufficiencies Due to Metabolic Alterations Regulated by the Inhibitory Receptor PD-1 Are an Early Driver of CD8(+) T Cell Exhaustion. (2016) (496)
- Liver-Infiltrating Lymphocytes in Chronic Human Hepatitis C Virus Infection Display an Exhausted Phenotype with High Levels of PD-1 and Low Levels of CD127 Expression (2006) (492)
- Cutting Edge: Rapid In Vivo Killing by Memory CD8 T Cells1 (2003) (478)
- Reinvigorating exhausted HIV-specific T cells via PD-1–PD-1 ligand blockade (2006) (466)
- Selective expansion of a subset of exhausted CD8 T cells by αPD-L1 blockade (2008) (463)
- A role for the transcriptional repressor Blimp-1 in CD8(+) T cell exhaustion during chronic viral infection. (2009) (445)
- Molecular regulation of effector and memory T cell differentiation (2014) (441)
- Network analysis reveals centrally connected genes and pathways involved in CD8+ T cell exhaustion versus memory. (2012) (440)
- Distinct antibody and memory B cell responses in SARS-CoV-2 naïve and recovered individuals following mRNA vaccination (2021) (433)
- Therapeutic use of IL-2 to enhance antiviral T-cell responses in vivo (2003) (421)
- Anomalous Type 17 Response to Viral Infection by CD8+ T Cells Lacking T-bet and Eomesodermin (2008) (415)
- mRNA vaccines induce durable immune memory to SARS-CoV-2 and variants of concern (2021) (410)
- Molecular and transcriptional basis of CD4⁺ T cell dysfunction during chronic infection. (2014) (408)
- Cutting Edge: The Transcription Factor Eomesodermin Enables CD8+ T Cells To Compete for the Memory Cell Niche (2010) (399)
- A Single Dose of Neoadjuvant PD-1 Blockade Predicts Clinical Outcomes in Resectable Melanoma (2019) (382)
- CD8 T cell dysfunction during chronic viral infection. (2007) (380)
- Synergistic Reversal of Intrahepatic HCV-Specific CD8 T Cell Exhaustion by Combined PD-1/CTLA-4 Blockade (2009) (380)
- Cutting Edge: IL-12 Inversely Regulates T-bet and Eomesodermin Expression during Pathogen-Induced CD8+ T Cell Differentiation1 (2006) (373)
- T-bet represses expression of PD-1 and sustains virus-specific CD8 T cell responses during chronic infection (2011) (365)
- Integrative genomic analysis of HIV-specific CD8+ T cells reveals that PD-1 inhibits T cell function by upregulating BATF (2010) (350)
- Cutting Edge: Gut Microenvironment Promotes Differentiation of a Unique Memory CD8 T Cell Population (2006) (346)
- Induction of T-cell Immunity Overcomes Complete Resistance to PD-1 and CTLA-4 Blockade and Improves Survival in Pancreatic Carcinoma (2015) (344)
- Lung Niches for the Generation and Maintenance of Tissue-resident Memory T cells (2013) (335)
- Developmental Relationships of Four Exhausted CD8+ T Cell Subsets Reveals Underlying Transcriptional and Epigenetic Landscape Control Mechanisms. (2020) (331)
- Multifactorial T-cell Hypofunction That Is Reversible Can Limit the Efficacy of Chimeric Antigen Receptor–Transduced Human T cells in Solid Tumors (2014) (322)
- Genetic absence of PD-1 promotes accumulation of terminally differentiated exhausted CD8+ T cells (2015) (320)
- Viral antigen and extensive division maintain virus-specific CD8 T cells during chronic infection (2007) (307)
- Requirement for T-bet in the aberrant differentiation of unhelped memory CD8+ T cells (2007) (305)
- Functional restoration of HCV-specific CD8 T cells by PD-1 blockade is defined by PD-1 expression and compartmentalization. (2008) (301)
- Cellular and humoral immune responses following SARS-CoV-2 mRNA vaccination in patients with multiple sclerosis on anti-CD20 therapy (2021) (297)
- Bone Marrow Is a Preferred Site for Homeostatic Proliferation of Memory CD8 T Cells (2005) (291)
- TCF-1-Centered Transcriptional Network Drives an Effector versus Exhausted CD8 T Cell-Fate Decision. (2019) (290)
- A mouse model of vitiligo with focused epidermal depigmentation requires IFN-γ for autoreactive CD8+ T cell accumulation in the skin (2011) (274)
- Single-Cell RNA-Seq Reveals TOX as a Key Regulator of CD8+ T cell Persistence in Chronic Infection (2019) (272)
- CD8+ T cells contribute to survival in patients with COVID-19 and hematologic cancer (2021) (266)
- Generation and maintenance of immunological memory. (2004) (265)
- The transcription factor BATF operates as an essential differentiation checkpoint in early effector CD8+ T cells (2014) (264)
- TSLP promotes interleukin-3-independent basophil haematopoiesis and type 2 inflammation (2011) (246)
- Coregulation of CD8+ T cell exhaustion during chronic viral infection by multiple inhibitory receptors (2008) (245)
- T cell exhaustion during persistent viral infections. (2015) (244)
- CD39 Expression Identifies Terminally Exhausted CD8+ T Cells (2015) (241)
- Rapid induction of antigen-specific CD4+ T cells is associated with coordinated humoral and cellular immunity to SARS-CoV-2 mRNA vaccination (2021) (232)
- Virus-helminth coinfection reveals a microbiota-independent mechanism of immunomodulation (2014) (230)
- Progressive Loss of Memory T Cell Potential and Commitment to Exhaustion during Chronic Viral Infection (2012) (228)
- Differential Sensitivity of Naive and Memory CD8+ T Cells to Apoptosis in Vivo1 (2002) (228)
- Enhancing therapeutic vaccination by blocking PD-1–mediated inhibitory signals during chronic infection (2008) (225)
- IL-10, T cell exhaustion and viral persistence. (2007) (225)
- Adenoviral vectors persist in vivo and maintain activated CD8+ T cells: implications for their use as vaccines. (2007) (221)
- The role of programming in memory T-cell development. (2004) (214)
- Opposing Functions of Interferon Coordinate Adaptive and Innate Immune Responses to Cancer Immune Checkpoint Blockade (2019) (214)
- Seasonal human coronavirus antibodies are boosted upon SARS-CoV-2 infection but not associated with protection (2020) (208)
- The long non-coding RNA Morrbid regulates Bim and short-lived myeloid cell lifespan (2016) (205)
- Costimulatory and Coinhibitory Receptor Pathways in Infectious Disease. (2016) (199)
- Combination Cancer Therapies with Immune Checkpoint Blockade: Convergence on Interferon Signaling (2016) (197)
- Janus kinase inhibition lessens inflammation and ameliorates disease in murine models of hemophagocytic lymphohistiocytosis. (2016) (188)
- The induction of virus-specific CTL as a function of increasing epitope expression: responses rise steadily until excessively high levels of epitope are attained. (1999) (187)
- Seasonal human coronavirus antibodies are boosted upon SARS-CoV-2 infection but not associated with protection (2021) (177)
- MicroRNA-155 controls CD8+ T cell responses by regulating interferon signaling (2013) (175)
- Behavior of parasite-specific effector CD8+ T cells in the brain and visualization of a kinesis-associated system of reticular fibers. (2009) (166)
- Decade-long leukaemia remissions with persistence of CD4+ CAR T cells (2022) (164)
- The gut microbiota regulates white adipose tissue inflammation and obesity via a family of microRNAs (2019) (155)
- Priority COVID-19 vaccination for patients with cancer while vaccine supply is limited. (2020) (154)
- Strength of Stimulus and Clonal Competition Impact the Rate of Memory CD8 T Cell Differentiation12 (2007) (152)
- Dynamic programmed death 1 expression by virus-specific CD8 T cells correlates with the outcome of acute hepatitis B. (2008) (151)
- Cutting Edge: IL-4, IL-21, and IFN-γ Interact To Govern T-bet and CD11c Expression in TLR-Activated B Cells (2016) (149)
- A Role for the Chemokine RANTES in Regulating CD8 T Cell Responses during Chronic Viral Infection (2011) (145)
- Inhibitory Receptors on Lymphocytes: Insights from Infections (2012) (145)
- Impact of Epitope Escape on PD-1 Expression and CD8 T-Cell Exhaustion during Chronic Infection (2009) (144)
- Circulating CXCR5+PD-1+ Response Predicts Influenza Vaccine Antibody Responses in Young Adults but not Elderly Adults (2014) (143)
- Role of PD-1 in regulating acute infections. (2010) (141)
- The diversity of costimulatory and inhibitory receptor pathways and the regulation of antiviral T cell responses. (2009) (140)
- IL-25 simultaneously elicits distinct populations of innate lymphoid cells and multipotent progenitor type 2 (MPPtype2) cells (2013) (134)
- Regulator of Fatty Acid Metabolism, Acetyl Coenzyme A Carboxylase 1, Controls T Cell Immunity (2014) (134)
- Changing immunodominance patterns in antiviral CD8 T-cell responses after loss of epitope presentation or chronic antigenic stimulation. (2003) (132)
- Cooperativity Between CD8+ T Cells, Non-Neutralizing Antibodies, and Alveolar Macrophages Is Important for Heterosubtypic Influenza Virus Immunity (2013) (132)
- Cutting Edge: B Cell–Intrinsic T-bet Expression Is Required To Control Chronic Viral Infection (2016) (131)
- Perforin and IL-2 Upregulation Define Qualitative Differences among Highly Functional Virus-Specific Human CD8+ T Cells (2010) (129)
- Increased programmed death-1 expression on CD4+ T cells in cutaneous T-cell lymphoma: implications for immune suppression. (2010) (128)
- Successive annual influenza vaccination induces a recurrent oligoclonotypic memory response in circulating T follicular helper cells (2017) (128)
- TCR Signal Transduction in Antigen-Specific Memory CD8 T Cells1 (2003) (127)
- Low CD8 T-Cell Proliferative Potential and High Viral Load Limit the Effectiveness of Therapeutic Vaccination (2005) (122)
- Innate lymphoid cells promote lung tissue homeostasis following acute influenza virus infection (2011) (122)
- Tissue-Specific Differences in PD-1 and PD-L1 Expression during Chronic Viral Infection: Implications for CD8 T-Cell Exhaustion (2009) (119)
- New-Onset IgG Autoantibodies in Hospitalized Patients with COVID-19 (2021) (118)
- Point mutation flanking a CTL epitope ablates in vitro and in vivo recognition of a full-length viral protein. (1997) (118)
- Deep immune profiling of COVID-19 patients reveals patient heterogeneity and distinct immunotypes with implications for therapeutic interventions (2020) (115)
- Faculty Opinions recommendation of Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals. (2009) (111)
- Differential Localization of T-bet and Eomes in CD8 T Cell Memory Populations (2013) (111)
- New-onset IgG autoantibodies in hospitalized patients with COVID-19 (2021) (110)
- Defective CD8 T Cell Responses in Aged Mice Are Due to Quantitative and Qualitative Changes in Virus-Specific Precursors (2012) (110)
- The Transcription Factor T-bet Resolves Memory B Cell Subsets with Distinct Tissue Distributions and Antibody Specificities in Mice and Humans. (2020) (110)
- Generation of CD8+ T Cell Memory in Response to Low, High, and Excessive Levels of Epitope1 (2002) (109)
- Identification and characterization of HIV-specific resident memory CD8+ T cells in human lymphoid tissue (2018) (108)
- Non-conventional Inhibitory CD4+Foxp3-PD-1hi T Cells as a Biomarker of Immune Checkpoint Blockade Activity. (2018) (108)
- SARS-CoV-2 seroprevalence among parturient women in Philadelphia (2020) (104)
- B Cell Antigen Presentation in the Initiation of Follicular Helper T Cell and Germinal Center Differentiation (2014) (101)
- Chronic bystander infections and immunity to unrelated antigens. (2012) (96)
- CD40 agonistic monoclonal antibody APX005M (sotigalimab) and chemotherapy, with or without nivolumab, for the treatment of metastatic pancreatic adenocarcinoma: an open-label, multicentre, phase 1b study. (2021) (95)
- The Loss of TET2 Promotes CD8+ T Cell Memory Differentiation (2018) (93)
- T follicular helper cells in human efferent lymph retain lymphoid characteristics. (2019) (93)
- Liver environment and HCV replication affect human T-cell phenotype and expression of inhibitory receptors. (2014) (92)
- MyD88 Plays a Critical T Cell-Intrinsic Role in Supporting CD8 T Cell Expansion during Acute Lymphocytic Choriomeningitis Virus Infection1 (2008) (92)
- Deep immune profiling of MIS-C demonstrates marked but transient immune activation compared to adult and pediatric COVID-19 (2021) (91)
- Bystander chronic infection negatively impacts development of CD8(+) T cell memory. (2012) (90)
- Awakening the immune system with radiation: Optimal dose and fractionation. (2015) (89)
- Deep Immune Profiling of MIS-C demonstrates marked but transient immune activation compared to adult and pediatric COVID-19 (2020) (83)
- Spatial distribution and function of T follicular regulatory cells in human lymph nodes (2018) (79)
- Persistent Enteric Murine Norovirus Infection Is Associated with Functionally Suboptimal Virus-Specific CD8 T Cell Responses (2013) (79)
- Targeting of antigen to the herpesvirus entry mediator augments primary adaptive immune responses (2008) (78)
- Identification of an Evolutionarily Conserved Transcriptional Signature of CD8 Memory Differentiation That Is Shared by T and B Cells1 (2008) (78)
- T-cell receptor signals direct the composition and function of the memory CD8+ T-cell pool. (2010) (75)
- TIGIT and CD226: tipping the balance between costimulatory and coinhibitory molecules to augment the cancer immunotherapy toolkit. (2014) (74)
- SnapShot: T Cell Exhaustion (2015) (73)
- Protein Energy Malnutrition Impairs Homeostatic Proliferation of Memory CD8 T Cells (2012) (72)
- Toll-like receptor 7 is required for effective adaptive immune responses that prevent persistent virus infection. (2012) (72)
- Cutting Edge: Persistently Open Chromatin at Effector Gene Loci in Resting Memory CD8+ T Cells Independent of Transcriptional Status (2011) (70)
- A phase I trial of pembrolizumab with hypofractionated radiotherapy in patients with metastatic solid tumours (2018) (69)
- Increased T‐bet is associated with senescence of influenza virus‐specific CD8 T cells in aged humans (2013) (68)
- Vaccine-elicited CD4 T cells induce immunopathology after chronic LCMV infection (2015) (67)
- Acquired transcriptional programming in functional and exhausted virus-specific CD8 T cells. (2012) (67)
- Epigenetic scarring of exhausted T cells hinders memory differentiation upon eliminating chronic antigenic stimulation (2021) (65)
- Engagement of NKG2D on Bystander Memory CD8 T Cells Promotes Increased Immunopathology following Leishmania major Infection (2014) (65)
- Long-Term Persistence of Exhausted CD8 T Cells in Chronic Infection Is Regulated by MicroRNA-155. (2018) (65)
- Viral Antigen Induces Differentiation of Foxp3+ Natural Regulatory T Cells in Influenza Virus–Infected Mice (2013) (64)
- Cell-Intrinsic Defects in the Proliferative Response of Antiviral Memory CD8 T Cells in Aged Mice upon Secondary Infection (2010) (64)
- Long-term outcomes of a phase I study of agonist CD40 antibody and CTLA-4 blockade in patients with metastatic melanoma (2018) (64)
- Plasmacytoid Dendritic Cells Are Dispensable during Primary Influenza Virus Infection1 (2009) (63)
- Differential Induction of TLR3-Dependent Innate Immune Signaling by Closely Related Parasite Species (2014) (61)
- A brief history of CD8 T cells (2007) (60)
- Integrating genomic signatures for immunologic discovery. (2010) (59)
- Deep immune profiling by mass cytometry links human T and NK cell differentiation and cytotoxic molecule expression patterns. (2017) (59)
- Homeostatic proliferation but not the generation of virus specific memory CD8 T cells is impaired in the absence of IL-15 or IL-15Ralpha. (2002) (59)
- HIV-specific CD8 T cells express low levels of IL-7Ralpha: implications for HIV-specific T cell memory. (2006) (59)
- miR-150 Regulates Memory CD8 T Cell Differentiation via c-Myb. (2017) (58)
- mRNA Vaccination Induces Durable Immune Memory to SARS-CoV-2 with Continued Evolution to Variants of Concern (2021) (58)
- In vivo CD8+ T cell CRISPR screening reveals control by Fli1 in infection and cancer (2021) (58)
- An Interferon Paradox (2013) (58)
- Type I Interferon Receptor Deficiency in Dendritic Cells Facilitates Systemic Murine Norovirus Persistence Despite Enhanced Adaptive Immunity (2016) (57)
- Survival of Effector CD8+ T Cells during Influenza Infection Is Dependent on Autophagy (2015) (57)
- Hypogammaglobulinemia and exacerbated CD8 T-cell-mediated immunopathology in SAP-deficient mice with chronic LCMV infection mimics human XLP disease. (2006) (56)
- Efficient recall of Omicron-reactive B cell memory after a third dose of SARS-CoV-2 mRNA vaccine (2022) (55)
- Dysfunctional HIV-specific CD8+ T cell proliferation is associated with increased caspase-8 activity and mediated by necroptosis. (2014) (55)
- Group 1 Innate Lymphoid Cell Lineage Identity Is Determined by a cis-Regulatory Element Marked by a Long Non-coding RNA. (2017) (54)
- Immunologic perturbations in severe COVID-19/SARS-CoV-2 infection (2020) (54)
- Understanding T cell responses to COVID-19 is essential for informing public health strategies (2022) (51)
- Efficient recall of Omicron-reactive B cell memory after a third dose of SARS-CoV-2 mRNA vaccine (2022) (51)
- Transcription factor regulation of CD8+ T‐cell memory and exhaustion (2010) (51)
- Dynamic decrease in PD-1 expression correlates with HBV-specific memory CD8 T-cell development in acute self-limited hepatitis B patients. (2009) (50)
- Cutting Edge: CXCR4 Is Critical for CD8+ Memory T Cell Homeostatic Self-Renewal but Not Rechallenge Self-Renewal (2014) (50)
- ST2 contributes to T-cell hyperactivation and fatal hemophagocytic lymphohistiocytosis in mice. (2016) (48)
- Re-evaluating the Generation of a “Proteasome-Independent” MHC Class I-Restricted CD8 T Cell Epitope1 (2006) (47)
- Viral FLIP Impairs Survival of Activated T Cells and Generation of CD8+ T Cell Memory1 (2004) (47)
- AAV8 induces tolerance in murine muscle as a result of poor APC transduction, T cell exhaustion, and minimal MHCI upregulation on target cells. (2014) (46)
- Immune Memory and Exhaustion: Clinically Relevant Lessons from the LCMV Model. (2015) (45)
- The PD-1 Pathway Regulates Development and Function of Memory CD8+ T Cells following Respiratory Viral Infection. (2020) (43)
- The Identity of Human Tissue-Emigrant CD8+ T Cells (2020) (42)
- The contribution of epigenetic memory to immunologic memory. (2011) (41)
- BACH2 Enforces the Transcriptional and Epigenetic Programs of Stem-Like CD8+ T cells (2021) (41)
- Antigen exposure shapes the ratio between antigen-specific Tregs and conventional T cells in human peripheral blood (2016) (39)
- Germinal center responses to SARS-CoV-2 mRNA vaccines in healthy and immunocompromised individuals (2022) (39)
- Rapid induction of antigen-specific CD4+ T cells guides coordinated humoral and cellular immune responses to SARS-CoV-2 mRNA vaccination (2021) (39)
- SARS-CoV-2 Seroprevalence Among Parturient Women (2020) (38)
- Elevated Expression of CD160 and 2B4 Defines a Cytolytic HIV-Specific CD8+ T-Cell Population in Elite Controllers. (2015) (38)
- CD4+ T Cell Differentiation in Chronic Viral Infections: The Tfh Perspective. (2017) (38)
- Lymphocytic Choriomeningitis Virus Expands a Population of NKG2D+CD8+ T Cells That Exacerbates Disease in Mice Coinfected with Leishmania major (2015) (37)
- Germinal center responses to SARS-CoV-2 mRNA vaccines in healthy and immunocompromised individuals (2021) (37)
- Signatures of COVID-19 severity and immune response in the respiratory tract microbiome (2021) (37)
- Optimized retroviral transduction of mouse T cells for in vivo assessment of gene function (2017) (37)
- Role of nuclear localization in the regulation and function of T-bet and Eomes in exhausted CD8 T cells (2021) (36)
- Pembrolizumab for B-cell lymphomas relapsing after or refractory to CD19-directed CAR T-cell therapy. (2021) (36)
- Unique challenges for glioblastoma immunotherapy - Discussions across neuro-oncology and non-neuro-oncology experts in cancer immunology. (2020) (36)
- Efficient and Qualitatively Distinct MHC Class I-Restricted Presentation of Antigen Targeted to the Endoplasmic Reticulum1 (2002) (35)
- The long noncoding RNA Morrbid regulates CD8 T cells in response to viral infection (2019) (35)
- Inhibitory signaling sustains a distinct early memory CD8+ T cell precursor that is resistant to DNA damage (2021) (34)
- Molecular Signature of CD8+ T Cell Exhaustion during Chronic Viral Infection (DOI:10.1016/j.immuni.2007.09.006) (2007) (34)
- CD8 T cells compensate for impaired humoral immunity in COVID-19 patients with hematologic cancer (2021) (34)
- Neoadjuvant Selicrelumab, an Agonist CD40 Antibody, Induces Changes in the Tumor Microenvironment in Patients with Resectable Pancreatic Cancer (2021) (33)
- Loss of tonic T-cell receptor signals alters the generation but not the persistence of CD8+ memory T cells. (2010) (32)
- Technical Advance: Fluorescent reporter reveals insights into eomesodermin biology in cytotoxic lymphocytes (2013) (32)
- Diminished primary CD8 T cell response to viral infection during protein energy malnutrition in mice is due to changes in microenvironment and low numbers of viral-specific CD8 T cell precursors. (2008) (31)
- Erythrocytes Reveal Complement Activation in Patients with COVID-19 (2020) (30)
- SARS-CoV-2 antibody responses in children with MIS-C and mild and severe COVID-19 (2020) (30)
- Pregnancy promotes tolerance to future offspring by programming selective dysfunction in long‐lived maternal T cells (2017) (30)
- HIV-specific CD 8 T cells express low levels of IL-7 R alpha : Implications for HIV-specific T cell memory (30)
- Longitudinal Analysis Reveals Distinct Antibody and Memory B Cell Responses in SARS-CoV2 Naïve and Recovered Individuals Following mRNA Vaccination (2021) (30)
- Sotigalimab and/or nivolumab with chemotherapy in first-line metastatic pancreatic cancer: clinical and immunologic analyses from the randomized phase 2 PRINCE trial (2022) (29)
- Deconstructing development (2013) (29)
- Limited immune surveillance in lymphoid tissue by cytolytic CD4+ T cells during health and HIV disease (2018) (28)
- K12/SECTM1, an interferon‐γ regulated molecule, synergizes with CD28 to costimulate human T cell proliferation (2012) (28)
- Abstract CT137: Combination of agonistic CD40 monoclonal antibody CP-870,893 and anti-CTLA-4 antibody tremelimumab in patients with metastatic melanoma (2015) (27)
- Distinct mechanisms govern populations of myeloid-derived suppressor cells in chronic viral infection and cancer. (2021) (27)
- De-Risking Immunotherapy: Report of a Consensus Workshop of the Cancer Immunotherapy Consortium of the Cancer Research Institute (2016) (27)
- Cytosolic delivery of viral nucleoprotein by listeriolysin O-liposome induces enhanced specific cytotoxic T lymphocyte response and protective immunity. (2004) (26)
- What Is the Predictive Value of Animal Models for Vaccine Efficacy in Humans? Consideration of Strategies to Improve the Value of Animal Models. (2018) (26)
- Vaccine-Induced Boosting of Influenza Virus-Specific CD4 T Cells in Younger and Aged Humans (2013) (26)
- PPT1 inhibition enhances the antitumor activity of anti–PD-1 antibody in melanoma (2020) (25)
- Antiviral memory CD8 T-cell differentiation, maintenance, and secondary expansion occur independently of MyD88. (2011) (25)
- The Transcription Factor T-Bet Is Regulated by MicroRNA-155 in Murine Anti-Viral CD8+ T Cells via SHIP-1 (2017) (23)
- Vaccine-induced ICOS+CD38+ circulating Tfh are sensitive biosensors of age-related changes in inflammatory pathways (2021) (23)
- Genetic manipulation of the ApoF/Stat2 locus supports an important role for type I interferon signaling in atherosclerosis. (2014) (22)
- HIV Skews the Lineage-Defining Transcriptional Profile of Mycobacterium tuberculosis–Specific CD4+ T Cells (2016) (22)
- Proteomic profiling of MIS-C patients indicates heterogeneity relating to interferon gamma dysregulation and vascular endothelial dysfunction (2021) (21)
- Enhanced T Cell Function in a Mouse Model of Human Glycosylation (2013) (20)
- The Orphan Nuclear Receptor TLX Is an Enhancer of STAT1-Mediated Transcription and Immunity to Toxoplasma gondii (2015) (20)
- Memory T-Cell Heterogeneity and Terminology. (2021) (19)
- Divergent clonal differentiation trajectories of T cell exhaustion (2021) (19)
- Differentiation of CD8 T cells in response to acute and chronic viral infections: implications for HIV vaccine development. (2005) (19)
- Human epigenetic and transcriptional T cell differentiation atlas for identifying functional T cell-specific enhancers. (2022) (18)
- Editorial: Therapeutic potential of targeting BTLA (2009) (18)
- Hidden Caveat of Inducible Cre Recombinase. (2019) (17)
- Erythrocytes identify complement activation in patients with COVID-19 (2021) (17)
- TCF-1 flips the switch on Eomes. (2010) (16)
- Transient expression of ZBTB32 in anti-viral CD8+ T cells limits the magnitude of the effector response and the generation of memory (2017) (16)
- Shared and distinct biological circuits in effector, memory and exhausted CD8+ T cells revealed by temporal single-cell transcriptomics and epigenetics (2022) (15)
- PD-1 directed immunotherapy alters Tfh and humoral immune responses to seasonal influenza vaccine (2022) (15)
- The importance of cooperation: partnerless NFAT induces T cell exhaustion. (2015) (15)
- SARS-CoV-2 antibody responses in children with MIS-C and mild and severe COVID-19 (2020) (15)
- Signatures of COVID-19 Severity and Immune Response in the Respiratory Tract Microbiome (2021) (15)
- Genomic Circuitry Underlying Immunological Response to Pediatric Acute Respiratory Infection. (2018) (14)
- Immunosurveillance by antiangiogenesis: tumor growth arrest by T cell-derived thrombospondin-1. (2014) (14)
- Influenza Virus Specific CD8+ T Cells Exacerbate Infection Following High Dose Influenza Challenge of Aged Mice (2013) (14)
- Signaling through FcγRIIA and the C5a-C5aR pathway mediates platelet hyperactivation in COVID-19 (2021) (14)
- Non-conventional Inhibitory CD4+Foxp3-PD-1hi T Cells as a Biomarker of Immune Checkpoint Blockade Activity. (2018) (13)
- Trib1 regulates T cell differentiation during chronic infection by restraining the effector program (2020) (13)
- Cytomegalovirus Latent Infection is Associated with an Increased Risk of COVID-19-Related Hospitalization (2022) (13)
- Immunity Resource Molecular Signature of CD 8 + T Cell Exhaustion during Chronic Viral Infection (13)
- implications for their use as vaccines Adenoviral vectors persist in vivo and maintain activated CD8+ T cells: (2013) (12)
- SARS-CoV-2 infections elicit higher levels of original antigenic sin antibodies compared with SARS-CoV-2 mRNA vaccinations (2021) (11)
- Autoreactive CD8+ T cells are restrained by an exhaustion-like program that is maintained by LAG3 (2022) (11)
- Sero-monitoring of health care workers reveals complex relationships between common coronavirus antibodies and SARS-CoV-2 severity (2021) (11)
- Phase I trial of autologous cMET-directed CAR-t cells administered intravenously in patients with melanoma & breast carcinoma. (2020) (11)
- Mice Lacking the Purinergic Receptor P2X5 Exhibit Defective Inflammasome Activation and Early Susceptibility to Listeria monocytogenes (2020) (11)
- Adaptive Immunity: Neutralizing, Eliminating, and Remembering for the Next Time (2016) (11)
- Health care worker seromonitoring reveals complex relationships between common coronavirus antibodies and COVID-19 symptom duration (2021) (11)
- CD8+ T Cell Exhaustion During Persistent Viral Infection is Regulated Independently of the Virus-Specific T Cell Receptor (2013) (10)
- A statistical framework for differential pseudotime analysis with multiple single-cell RNA-seq samples (2021) (10)
- Acetyl CoA Carboxylase 2 Is Dispensable for CD8+ T Cell Responses (2015) (9)
- CD8 T Cell Memory Increases Immunopathology in the Perforin-Deficient Model of Hemophagocytic Lymphohistiocytosis Secondary to TNF-α (2018) (9)
- Signaling Through FcγRIIA and the C5a-C5aR Pathway Mediate Platelet Hyperactivation in COVID-19 (2022) (9)
- Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) Antibody Responses in Children With Multisystem Inflammatory Syndrome in Children (MIS-C) and Mild and Severe Coronavirus Disease 2019 (COVID-19) (2020) (9)
- The hedgehog pathway suppresses neuropathogenesis in CD4 T cell-driven inflammation. (2021) (9)
- A boost with SARS-CoV-2 BNT162b2 mRNA vaccine elicits strong humoral responses independently of the interval between the first two doses (2022) (8)
- Inhibitory receptors: whose side are they on? (2007) (8)
- MyD 88 Plays a Critical T Cell-Intrinsic Role in Supporting CD 8 T Cell Expansion during Acute Lymphocytic Choriomeningitis Virus Infection 1 (2008) (8)
- Multisystem Inflammation and Organ Dysfunction After BNT162b2 Messenger RNA Coronavirus Disease 2019 Vaccination (2021) (7)
- Pathogen-Induced CD 8 T-bet and Eomesodermin Expression during Cutting Edge : IL-12 Inversely Regulates (2006) (7)
- NFAT-dependent and -independent exhaustion circuits program maternal CD8 T cell hypofunction in pregnancy (2021) (7)
- Chronic viral infection promotes early germinal center exit of B cells and impaired antibody development (2019) (6)
- Norovirus-Specific CD8+ T Cell Responses in Human Blood and Tissues (2021) (6)
- Challenging systemic barriers to promote the inclusion, recruitment, and retention of URM faculty in STEM. (2021) (6)
- How Did We Get a COVID-19 Vaccine in Less Than 1 Year? (2021) (6)
- Author Correction: Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia (2021) (5)
- Use of vaccinia virus expression vectors to investigate antigen processing and presentation. (2001) (5)
- The transcription factor BATF operates as an essential differentiation checkpoint in early effector CD8[superscript +] T cells (2014) (5)
- Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response (2018) (4)
- Vaccine-induced ICOS+CD38+ cTfh are sensitive biosensors of age-related changes in inflammatory pathways (2019) (4)
- Combining Radiation with Immunotherapy: The University of Pennsylvania Experience. (2020) (4)
- Antiviral memory CD 8 T-cell differentiation , maintenance , and secondary expansion occur independently of MyD 88 (2011) (3)
- Exploration of T-Cell Diversity Using Mass Cytometry. (2020) (3)
- Cutting Edge : The Transcription Factor Wherry (2010) (3)
- A long interval between priming and boosting SARS-CoV-2 mRNA vaccine doses enhances B cell responses with limited impact on T cell immunity (2022) (3)
- Batf-mediated Epigenetic Control of Effector CD8+ T Cell Differentiation (2021) (3)
- Identification of Functional Determinants of Response and Resistance to CD19 Chimeric Antigen Receptor (CAR) T-Cell Therapy of Chronic Lymphocytic Leukemia (2017) (3)
- Proteomic Profiling of MIS-C Patients Reveals Heterogeneity Relating to Interferon Gamma Dysregulation and Vascular Endothelial Dysfunction (2021) (3)
- In vivo CRISPR screening identifies Fli1 as a transcriptional safeguard that restrains effector CD8 T cell differentiation during infection and cancer (2020) (3)
- A Cre-driven allele-conditioning line to interrogate CD4+ conventional T cells. (2021) (3)
- MicroRNA-29a attenuates CD8 T cell exhaustion and induces memory-like CD8 T cells during chronic infection (2022) (2)
- Corrigendum: Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin (2006) (2)
- Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia (2018) (2)
- Unravelling CD4 T cell Dysfunction During Chronic Infection (39.17) (2010) (2)
- Subsetting the subsets: Heterogeneity and developmental relationships of T cells in human tumors (2021) (2)
- An extended SARS-CoV-2 mRNA vaccine prime-boost interval enhances B cell immunity with limited impact on T cells (2022) (2)
- Immune dysregulation in human ITCH deficiency successfully treated with hematopoietic cell transplantation. (2021) (2)
- Enhanced STAT5a activation rewires exhausted CD8 T cells during chronic stimulation to acquire a hybrid durable effector like state (2022) (2)
- Correction for Merenstein et al., “Signatures of COVID-19 Severity and Immune Response in the Respiratory Tract Microbiome” (2022) (2)
- Correction: Type I Interferon Receptor Deficiency in Dendritic Cells Facilitates Systemic Murine Norovirus Persistence Despite Enhanced Adaptive Immunity (2017) (2)
- Immune Stimulation With Recombinant Human Granulocyte Colony-Stimulating Factor for Coronavirus Disease 2019 (COVID-19)-Beware of Blind Spots. (2020) (2)
- TET2 controls differentiation of terminally exhausted CD8 T cells (2021) (1)
- Longitudinal single cell transcriptional and epigenetic mapping of effector, memory, and exhausted CD8 T cells reveals shared biological circuits across distinct cell fates (2022) (1)
- The Transcription Factor BATF Controls CD8+ T Cell Effector Differentiation (2013) (1)
- Molecular Basis of T-Cell Exhaustion (2013) (1)
- Abstract A056: Mechanisms of tumor response and resistance to radiation and dual checkpoint blockade in mice and patients (2016) (1)
- Validating a Proteomic Signature of Severe COVID-19 (2022) (1)
- Differentiation Impact the Rate of Memory CD 8 T Cell Strength of Stimulus and Clonal Competition (2007) (1)
- Human T follicular helper clones seed the germinal center-resident regulatory pool (2022) (1)
- Human T follicular regulatory cells (Tfr) able to inhibit antibody production are enriched at the lymph node T-B border and rare in germinal centers (2017) (1)
- Final results of a phase I “RadVax” trial of hypofractionated radiation combined with pembrolizumab in patients with metastatic solid tumors. (2021) (1)
- Efficient engineering of human and mouse primary cells using peptide-assisted genome editing. (2023) (1)
- Epitope Response to Low , High , and Excessive Levels T Cell Memory in + Generation of CD 8 (2002) (1)
- Impaired Lymphocyte Responses in Pediatric Sepsis Vary by Pathogen Type and are Associated with Features of Immunometabolic Dysregulation (2021) (1)
- Cancer cells resistant to immune checkpoint blockade acquire interferon-associated epigenetic memory to sustain T cell dysfunction (2023) (1)
- New Hope in the Search for Ebola Virus Treatments (2014) (1)
- IMMU-38. DEEP IMMUNOPROFILING OF HUMAN GLIOBLASTOMA (GBM) REVEALS DIFFERENCES IN THE TUMOR IMMUNE CELL INFILTRATE IN PATIENTS WITH HIGH VS. LOW PLASMA CELL-FREE DNA (CFDNA) (2021) (1)
- A Phase I Trial of Pembrolizumab with Hypofractionated Radiation Therapy (HFRT) in Patients with Metastatic Cancers (2018) (1)
- Webinar | Deciphering cancer: Modulating immunoregulatory pathways to treat tumors (2017) (1)
- Induction of a CD8 T cell intrinsic DNA damage and repair response is associated with clinical response to PD-1 blockade in uterine cancer (2022) (1)
- Abstract A123: Skewed CD4 and CD8 T-cell differentiation in pancreatic cancer patients (2019) (1)
- Innate lymphoid cells promote airway epithelial repair through the amphiregulin-EGFR pathway (P3250) (2013) (1)
- A distinct role for T‐bet in the maintenance of antigen‐specific CD8 T‐cells during chronic viral infection (2008) (1)
- Targeting TNFR2 to overcome acquired adaptive resistance to immune checkpoint blockade (2020) (1)
- Building effective collaborations for the study of COVID-19 across the severity spectrum (2022) (0)
- BACH2 enforces the transcriptional and epigenetic programs of stem-like CD8+ T cells (2021) (0)
- Memory T Cells in Tissues Maintenance of Effector-like Resident Antigen-Independent Differentiation and (2012) (0)
- Abstract B104: Impact of PD-1 blockade on epigenetic and transcriptional reprogramming of exhausted T cells (2016) (0)
- TET2 Regulates CD8+ T Cell Responses to Acute and Chronic Viral Infection (2015) (0)
- Methods and compositions for the treatment of persistent infektio-tions, and cancer by inhibiting programmed cell death-1 (PD-1) -pathwayen. (2006) (0)
- Su.66. Memory T-Cells in Mice and Humans Share a Common Molecular Program of Differentiation Regardless of Phenotype, Lineage Or Species (2006) (0)
- STAR0602, a novel TCR agonist antibody, demonstrates potent antitumor activity in refractory solid tumor models through the expansion of a novel, polyclonal effector memory T cell subset (2022) (0)
- Multi-ethnic Investigation of Risk and Immune Determinants of COVID-19 Outcomes (2021) (0)
- Immunological features in de novo and recurrent glioblastoma associate with survival outcomes. (2022) (0)
- Early onset and persistence of metabolic alterations in exhausted T cells is regulated by PD-1 (2016) (0)
- Single-cell RNA-seq reveals TOX as a key regulator of CD8+ T cell persistence in chronic infection (2019) (0)
- Author Correction: Epigenetic scarring of exhausted T cells hinders memory differentiation upon eliminating chronic antigenic stimulation (2021) (0)
- AutophagyInfluenza Infection Is Dependent on T Cells during + Survival of Effector CD8 (2015) (0)
- Faculty Opinions recommendation of Unbiased reconstruction of a mammalian transcriptional network mediating pathogen responses. (2010) (0)
- Author Correction: Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia (2021) (0)
- The pseudokinase Trib1 regulates the transition of exhausted T cells to a KLR+ CD8+ effector state and its deletion improves checkpoint blockade (2023) (0)
- Bystander chronic infection negatively impacts the development of CD8 T cell memory (76.6) (2012) (0)
- CD39 is highly up-regulated by exhausted CD8 + T cells in a mouse model of chronic infection. (2015) (0)
- A role for the transcription factor STAT5 in antagonizing CD8+ T cell exhaustion (2021) (0)
- T cell intrinsic DNA damage and repair response as a novel marker associated with clinical response to PD-1 blockade (2020) (0)
- Poor anti-viral immunity in aged mice is associated with defects in CD8 T cell recall responses (44.5) (2009) (0)
- Distinct Heterogeneity in the Naive T cell Compartments of Children and Adults (2022) (0)
- Abstract PO068: Distinct immune signatures predicting clinical response to PD-1 blockade therapy in gynecological cancers revealed by high-dimensional immune profiling (2021) (0)
- T cell responses to persisting and non-persisting infections (2013) (0)
- Status T Cells Independent of Transcriptional + CD8at Effector Gene Loci in Resting Memory Cutting Edge: Persistently Open Chromatin (2011) (0)
- Identification of flu-specific ICOS+CD38+ cTfh after influenza vaccination (2016) (0)
- Proteomic Analysis of COVID-19 Plasma Reveals Dysregulated TREM-1, I-17, and Tumor Microenvironment Pathways Associated with Disease Severity (2021) (0)
- A single dose of neoadjuvant PD-1 blockade predicts clinical outcomes in resectable melanoma (2019) (0)
- Memory T cells generated in youth function well in old age (49.8) (2011) (0)
- Abstract A52: Radiation and dual PD-L1 and CTLA4 checkpoint blockade non-redundantly improves tumor resistance, response, and immunity (2015) (0)
- Methods and compositions for the treatment of cancer and persistent infections by inhibiting the cell death pathway 1 (PD-1) programmed (2006) (0)
- Epigenetic scarring of exhausted T cells hinders memory differentiation upon eliminating chronic antigenic stimulation (2021) (0)
- LCMV-specific CD4 T cells induce immunopathology and impair immune protection following chronic LCMV infection (VIR1P.1132) (2015) (0)
- Abstract A166: Reprogramming of exhausted T-cells following cure of chronic viral infection (2019) (0)
- Compete for the Memory Cell Niche T Cells To + Eomesodermin Enables CD8 Cutting Edge: The Transcription Factor (2010) (0)
- Virus Infection Influenza Dispensable during Primary Plasmacytoid Dendritic Cells Are (2010) (0)
- P1.15-07 Phase II Study of Pembrolizumab and Itacitinib for First Line Treatment of Metastatic NSCLC Expressing PD-L1 (2022) (0)
- Abstract 3579: T cell intrinsic DNA damage and repair response as a novel marker associated with clinical response to PD-1 blockade (2022) (0)
- Immunity Commensal Bacteria Regulate Antiviral Immunity associated with defective activation of the inflammasome (2012) (0)
- Multiethnic Investigation of Risk and Immune Determinants of COVID-19 Outcomes (2022) (0)
- Abstract 2723: How BRCA1/2 mutations in TNBC affect TME and subsequently immune cell functions (2021) (0)
- Abstract CT005: T cell inflammation in the tumor microenvironment after agonist CD40 antibody: Clinical and translational results of a neoadjuvant clinical trial (2021) (0)
- AdultsResponses in Young Adults but not Elderly Predicts Influenza Vaccine Antibody Response + PD-1+ Circulating CXCR5 (2014) (0)
- The role of tripeptidyl peptidase II in MHC class I-restricted antigen processing and the effect of epitope density of CD8(+) T cell priming (1999) (0)
- Prior vaccination enhances immune responses during SARS-CoV-2 breakthrough infection with early activation of memory T cells followed by production of potent neutralizing antibodies (2023) (0)
- A phase I trial of pembrolizumab with hypofractionated radiotherapy in patients with metastatic solid tumours (2018) (0)
- CD39 expressed by CD8 + T cells in HCV infection is enzymatically active. (2015) (0)
- This information is current as TLR-Activated B Cells To Govern T-bet and CD 11 c Expression in Interact γ Cutting Edge : IL-4 , IL-21 , and (2016) (0)
- Abstract A38: Phase I study of combination immunotherapy with agonistic CD40 monoclonal antibody (mAb) CP-870,893 (αCD40) and anti-CTLA-4 antibody tremelimumab (treme) in patients with metastatic melanoma (2015) (0)
- Pregnancy Primes Graft-Destructive T Cell Memory.: Abstract# D2766 (2014) (0)
- Integrative Genomic Analysis of HIV-Specific CD8+ T Cells Reveals That PD-1 Inhibits T Cell Function by Upregulating the AP-1 Transcription Factor BATF. (2009) (0)
- Insights from Infections Inhibitory Receptors on Lymphocytes (2013) (0)
- L 8 Wildfire Smoke Exposure Activates CirculatingInnate Immune Cells (2021) (0)
- A31 REPROGRAMMING OF EXHAUSTED T CELLS FOLLOWING CURE OF CHRONIC VIRAL INFECTION (2018) (0)
- Memory T cells generated in youth function well in old age (2011) (0)
- Expression of a core gene module of anergy governs maternal CD8+ T cell hypofunction after pregnancy (2019) (0)
- Transcriptional Mapping of T Cell Memory Reveals That Chronic Viral Infection Arrests Memory Differentiation. (2005) (0)
- Abstract A197: The HMG transcription factor TOX induces a transcriptional and epigenetic program of CD8+ T-cell exhaustion in chronic infection and cancer (2019) (0)
- Homeostatic Proliferation of Memory CD 8 T Protein Energy Malnutrition Impairs (2011) (0)
- Terminally exhausted CD8+ T cells marked by high levels of CD39 are most impaired in their effector function. (2015) (0)
- Long-Term Persistence of Exhausted CD 8 T Cells in Chronic Infection Is Regulated by MicroRNA-155 Graphical (2018) (0)
- Final Results of a Phase I "RadVax" Trial of Hypofractionated Radiation Combined With Pembrolizumab in Patients With Metastatic Solid Tumors. (2021) (0)
- Faculty Opinions recommendation of T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes. (2009) (0)
- Aberrant Immunity: The Consequences of Overreacting or Underperforming (2016) (0)
- Interleukin-33 is a mediator of murine familial hemophagocytic lymphohistiocytosis (IRC5P.629) (2015) (0)
- CTLA-4-mediated suppressor effect by human T follicular regulatory cells (IRC11P.432) (2015) (0)
- Plasma Resistin Levels Are Associated with Acute Kidney Injury in Hospitalized COVID-19 Patients (2021) (0)
- Author Correction: Decade-long leukaemia remissions with persistence of CD4+ CAR T cells (2022) (0)
- Viral FLIP Impairs Survival of Activated T (2004) (0)
- Durable Response and Improved CD8 T Cell Plasticity in Lung Cancer Patients After PD1 Blockade and JAK Inhibition (2022) (0)
- Modulation of the subcellular localization of T-bet and Eomes alters CD8 exhaustion during chronic LCMV infection (2017) (0)
- Abstract IA04: Overcoming immune resistance with rationally designed combination immunotherapy (2020) (0)
- IMMUNOBIOLOGY Janus kinase inhibition lessens in fl ammation and ameliorates disease in murine models of hemophagocytic lymphohistiocytosis (2016) (0)
- Abstract B80: High dimensional DNA damage and repair (DDR) cytometric profiling of human T cell subsets revealed distinct DDR signatures (2020) (0)
- Author Correction: BACH2 enforces the transcriptional and epigenetic programs of stem-like CD8+ T cells (2021) (0)
- ICOS+CD38+ cTfh in peripheral blood and thoracic duct lymph. (2016) (0)
- Abstract B012: Characterizing tumor-induced exhaustion in melanoma patients treated with neoadjuvant pembrolizumab (2019) (0)
- Immune Responses to Persistent Viruses (2011) (0)
- Faculty Opinions recommendation of Neutralizing antibodies derived from the B cells of 1918 influenza pandemic survivors. (2009) (0)
- All Memory Lymphocytes Share a Common Differentiation Program. (2006) (0)
- InfectionAcute Lymphocytic Choriomeningitis Virus in Supporting CD8 T Cell Expansion during MyD88 Plays a Critical T Cell-Intrinsic Role (2008) (0)
- Differential Localization of T-bet and Eomes (2013) (0)
- Abstract 2858: Radiation and dual immune checkpoint blockade overcome tumor resistance and distinctly improve immunity (2015) (0)
- Transcriptional mapping of the anti-viral T cell response shows that impaired memory differentiation causes T cell dysfunction (2006) (0)
- Molecular analysis of age-associated B cells (ABCs) (69.7) (2012) (0)
- In vivo CRISPR Screening Identifies Fli1 as a Transcriptional Safeguard that Restrains Effector CD8 T Cell Differentiation During Infection and Cancer (2020) (0)
- The Methylcytosine Dioxygenase TET2 Regulates CD8 + T Cell Memory Differentiation (2016) (0)
- CD39 expression correlates with PD-1 expression and viral load in chronic viral infection. (2015) (0)
- P2.04-02 Effect of Chemotherapy, Chemoimmunotherapy, and Immunotherapy on Parameters of T Cell Exhaustion in Metastatic Non-Small Cell Lung Cancer (2019) (0)
- Abstract IA17: Molecular mechanisms of T-cell exhaustion and implications for immunotherapy (2020) (0)
- Reprogramming of exhausted T cells following elimination of chronic antigen exposure (2017) (0)
- Regulation of effective vs. ineffective B cell responses to chronic viral infections. (2016) (0)
- Immunological features of de novo and recurrent glioblastoma associate with survival in glioblastoma (2021) (0)
- Differential localization of T-bet and Eomes within distinct human CD8 T-cell memory populations (110.10) (2012) (0)
- Phase I Trial of Autologous RNA-electroporated cMET-directed CAR T cells Administered Intravenously in Patients with Melanoma & Breast Carcinoma (2023) (0)
- Bystander CD8 T cells produce granzyme B and promote exacerbated disease during Leishmania major infection (P3079) (2013) (0)
- MiR-150 negatively regulates CD8+ T cell memory formation (2016) (0)
- CTIM-35. A PHASE II STUDY OF GITR AGONIST INCAGN01876 AND PD-1 INHIBITOR RETIFANLIMAB IN COMBINATION WITH STEREOTACTIC RADIOTHERAPY IN PATIENTS WITH RECURRENT GLIOBLASTOMA (2022) (0)
- Human Norovirus-Specific T Cell Responses (2017) (0)
- Abstract IA06: Molecular basis of T cell exhaustion: Insights for immunotherapy (2016) (0)
- Modulation of TFH-like cells and anti-tumor activity of immune checkpoint blockade. (2018) (0)
- Developmental relationships of four exhausted CD8 T cell subsets reveals underlying transcriptional and epigenetic control mechanisms (2020) (0)
- Abstract IA01: Molecular basis of T cell exhaustion: Insights for immunotherapy (2015) (0)
- In Vitro Modeling of CD8 T Cell Exhaustion Enables CRISPR Screening to Reveal a Role for BHLHE40 (2023) (0)
- Defective Central Memory CD8+ T Cell Differentiation in the Absence of Eomesodermin. (2009) (0)
- Influence of viral specific memory cells on Leishmania major infection (164.12) (2012) (0)
- Title: Signaling through Fc g RIIA and the C5a-C5aR pathway mediates platelet hyperactivation in COVID-19 One-sentence summary: The Fc g RIIA and C5a-C5aR pathways mediate platelet hyperactivation in COVID-19 (2021) (0)
- Response, Resistance Mechanisms, and Biomarkers for Radiation and Immune Checkpoint Blockade (2015) (0)
- Novel roles for T-bet in CD8 differentiation during chronic viral infections (44.8) (2009) (0)
- Targeted to the Endoplasmic Reticulum Class I-Restricted Presentation of Antigen Efficient and Qualitatively Distinct MHC (2002) (0)
- TET2 deficiency promotes CD8+ T cell memory differentiation (2017) (0)
- Abstract LB-356: Deep immune profiling of de novo and recurrent glioblastoma (2020) (0)
- The Hobgoblin Argument: Why Law Schools Can Teach Trial Practice Effectively (1989) (0)
- A Cost Effectiveness Analysis of Breastfeeding Promotion Within Georgia's WIC Program (2017) (0)
- Issue Information (2008) (0)
- Abstract 4648: How inherited mutations affect single cells within the tumor microenvironment in breast tumors stratified by receptor status (2023) (0)
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