Eiki Kominami

Eiki Kominami's AcademicInfluence.com Rankings

Eiki Kominami

Philosophy

#6134

World Rank

#9116

Historical Rank

Logic

#3322

World Rank

#4460

Historical Rank

philosophy Degrees

Download Badge

Philosophy

Eiki Kominami's Degrees

PhD Life Sciences University of Tokyo
Masters Life Sciences University of Tokyo
Bachelors Life Sciences University of Tokyo

Why Is Eiki Kominami Influential?

(Suggest an Edit or Addition)

(See a Problem?)

Eiki Kominami's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing (2000) (6284)
Loss of autophagy in the central nervous system causes neurodegeneration in mice (2006) (3362)
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (2012) (2913)
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes (2008) (2360)
Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice (2005) (2262)
Homeostatic Levels of p62 Control Cytoplasmic Inclusion Body Formation in Autophagy-Deficient Mice (2007) (2045)
The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1 (2010) (1870)
A ubiquitin-like system mediates protein lipidation (2000) (1844)
LC3 and Autophagy. (2008) (1288)
LC3 conjugation system in mammalian autophagy (2004) (1267)
Lysosomal Turnover, but Not a Cellular Level, of Endogenous LC3 is a Marker for Autophagy (2005) (1058)
ER stress (PERK/eIF2α phosphorylation) mediates the polyglutamine-induced LC3 conversion, an essential step for autophagy formation (2007) (912)
Role for Rab7 in maturation of late autophagic vacuoles (2004) (877)
Delayed neuronal death in the CA1 pyramidal cell layer of the gerbil hippocampus following transient ischemia is apoptosis (1995) (838)
Structural Basis for Sorting Mechanism of p62 in Selective Autophagy* (2008) (711)
Autophagy is important in islet homeostasis and compensatory increase of beta cell mass in response to high-fat diet. (2008) (581)
Essential role for autophagy protein Atg7 in the maintenance of axonal homeostasis and the prevention of axonal degeneration (2007) (577)
Inhibition of autophagy prevents hippocampal pyramidal neuron death after hypoxic-ischemic injury. (2008) (476)
Autophagy pathway intersects with HIV-1 biosynthesis and regulates viral yields in macrophages (2009) (466)
The Atg8 conjugation system is indispensable for proper development of autophagic isolation membranes in mice. (2008) (462)
Interleukin 6 receptor antibody inhibits muscle atrophy and modulates proteolytic systems in interleukin 6 transgenic mice. (1996) (411)
Apg7p/Cvt2p: A novel protein-activating enzyme essential for autophagy. (1999) (394)
HsAtg4B/HsApg4B/Autophagin-1 Cleaves the Carboxyl Termini of Three Human Atg8 Homologues and Delipidates Microtubule-associated Protein Light Chain 3- and GABAA Receptor-associated Protein-Phospholipid Conjugates* (2004) (349)
Participation of autophagy in storage of lysosomes in neurons from mouse models of neuronal ceroid-lipofuscinoses (Batten disease). (2005) (344)
The Human Homolog of Saccharomyces cerevisiae Apg7p Is a Protein-activating Enzyme for Multiple Substrates Including Human Apg12p, GATE-16, GABARAP, and MAP-LC3* (2001) (332)
Autophagy and Neurodegeneration (2006) (314)
A novel protein‐conjugating system for Ufm1, a ubiquitin‐fold modifier (2004) (286)
Human Apg3p/Aut1p Homologue Is an Authentic E2 Enzyme for Multiple Substrates, GATE-16, GABARAP, and MAP-LC3, and Facilitates the Conjugation of hApg12p to hApg5p* (2002) (283)
Inhibition of ischaemic hippocampal neuronal death in primates with cathepsin B inhibitor CA‐074: a novel strategy for neuroprotection based on ‘calpain–cathepsin hypothesis’ (1998) (259)
Excess Peroxisomes Are Degraded by Autophagic Machinery in Mammals* (2006) (254)
Human Light Chain 3/MAP1LC3B Is Cleaved at Its Carboxyl-terminal Met121 to Expose Gly120 for Lipidation and Targeting to Autophagosomal Membranes* (2004) (242)
Lysosomal hydrolases of different classes are abnormally distributed in brains of patients with Alzheimer disease. (1991) (241)
Liver autophagy contributes to the maintenance of blood glucose and amino acid levels (2011) (240)
Selective turnover of p62/A170/SQSTM1 by autophagy (2008) (221)
The MAP1-LC3 conjugation system is involved in lipid droplet formation. (2009) (218)
The ALG-2-interacting Protein Alix Associates with CHMP4b, a Human Homologue of Yeast Snf7 That Is Involved in Multivesicular Body Sorting* (2003) (212)
Skeletal muscle gene expression in space‐flown rats (2004) (207)
Cathepsin D deficiency induces lysosomal storage with ceroid lipofuscin in mouse CNS neurons. (2000) (207)
Phosphatidylserine in Addition to Phosphatidylethanolamine Is an in Vitro Target of the Mammalian Atg8 Modifiers, LC3, GABARAP, and GATE-16* (2006) (207)
Inhibitory effect of di- and tripeptidyl aldehydes on calpains and cathepsins. (1990) (201)
MAP‐LC3, a promising autophagosomal marker, is processed during the differentiation and recovery of podocytes from PAN nephrosis (2003) (196)
Polyglutamine aggregates stimulate ER stress signals and caspase-12 activation. (2002) (190)
Cathepsin D Deficiency Induces Lysosomal Storage with Ceroid Lipofuscin in Mouse CNS Neurons (2000) (188)
Distribution of cathepsins B and H in rat tissues and peripheral blood cells. (1985) (187)
Knockdown of autophagy-related gene decreases the production of infectious Hepatitis C virus particles (2009) (175)
Podocyte Migration during Nephrotic Syndrome Requires a Coordinated Interplay between Cathepsin L and α3 Integrin* (2004) (172)
Multiple Pathways of TWEAK-Induced Cell Death1 (2002) (168)
Constitutive autophagy: vital role in clearance of unfavorable proteins in neurons (2007) (168)
A Novel Type of E3 Ligase for the Ufm1 Conjugation System* (2009) (154)
Regulation of a novel pathway for cell death by lysosomal aspartic and cysteine proteinases (1999) (154)
Muscle undergoes atrophy in association with increase of lysosomal cathepsin activity in interleukin-6 transgenic mouse. (1995) (151)
Interleukin-6 induces proteolysis by activating intracellular proteases (cathepsins B and L, proteasome) in C2C12 myotubes. (1995) (150)
Regulation of Cell Surface Expression of CTLA-4 by Secretion of CTLA-4-Containing Lysosomes Upon Activation of CD4+ T Cells1 (2000) (149)
Involvement of two different cell death pathways in retinal atrophy of cathepsin D-deficient mice (2003) (149)
Processing and Activation of Lysosomal Proteinases (2002) (148)
Characterization of new fluorogenic substrates for the rapid and sensitive assay of cathepsin E and cathepsin D. (1999) (144)
Procathepsin L degrades extracellular matrix proteins in the presence of glycosaminoglycans in vitro. (1995) (143)
Ubiquitin Ligase Cbl-b Is a Negative Regulator for Insulin-Like Growth Factor 1 Signaling during Muscle Atrophy Caused by Unloading (2009) (138)
Interaction of the Unc-51-like kinase and microtubule-associated protein light chain 3 related proteins in the brain: possible role of vesicular transport in axonal elongation. (2000) (137)
Structures and functions of lysosomal thiol proteinases and their endogenous inhibitor. (1983) (137)
CLC‐3 deficiency leads to phenotypes similar to human neuronal ceroid lipofuscinosis (2002) (136)
Sustained calpain activation associated with lysosomal rupture executes necrosis of the postischemic CA1 neurons in primates (2003) (132)
Crucial role for autophagy in degranulation of mast cells. (2011) (123)
Expression of proteinases and inflammatory cytokines in subchondral bone regions in the destructive joint of rheumatoid arthritis. (2001) (122)
Participation of cathepsins B and D in apoptosis of PC12 cells following serum deprivation. (1998) (121)
Specific storage of subunit c of mitochondrial ATP synthase in lysosomes of neuronal ceroid lipofuscinosis (Batten's disease). (1992) (119)
Sequestration of cytoplasmic enzymes in an autophagic vacuole-lysosomal system induced by injection of leupeptin. (1983) (118)
A new function of kininogens as thiol‐proteinase inhibitors: inhibition of papain and cathepsins B, H and L by bovine, rat and human plasma kininogens (1985) (115)
Fibroblast Growth Factor-Inducible 14 Mediates Multiple Pathways of TWEAK-Induced Cell Death1 (2003) (114)
Inhibition of hepatitis C virus replication by chloroquine targeting virus-associated autophagy (2009) (113)
Involvement of Nitric Oxide Released from Microglia–Macrophages in Pathological Changes of Cathepsin D-Deficient Mice (2001) (111)
Biosyntheses and processing of lysosomal cysteine proteinases in rat macrophages (1988) (111)
Molecular cloning and sequencing of cDNA for rat cathepsin L (1987) (110)
Free fatty acids stimulate autophagy in pancreatic β-cells via JNK pathway. (2010) (108)
GATE-16 and GABARAP are authentic modifiers mediated by Apg7 and Apg3. (2003) (108)
Both cathepsin B and cathepsin D are necessary for processing of ovalbumin as well as for degradation of class II MHC invariant chain. (1994) (108)
Studies on new intracellular proteases in various organs of rat. 2. Mode of limited proteolysis. (1975) (106)
Purification and tissue distribution of rat cathepsin L. (1986) (106)
LC3, a microtubule-associated protein1A/B light chain3, is involved in cytoplasmic lipid droplet formation. (2010) (106)
Solution Structure of Microtubule-associated Protein Light Chain 3 and Identification of Its Functional Subdomains* (2005) (98)
The C-terminal Region of an Apg7p/Cvt2p Is Required for Homodimerization and Is Essential for Its E1 Activity and E1-E2 Complex Formation* (2001) (93)
Autophagy in embryonic erythroid cells: its role in maturation. (2000) (92)
The Mouse APG10 Homologue, an E2-like Enzyme for Apg12p Conjugation, Facilitates MAP-LC3 Modification* (2003) (89)
Effect of proteinase inhibitors on intracellular processing of cathepsin B, H and L in rat macrophages (1988) (89)
Inhibitions by E-64 derivatives of rat liver cathepsin B and cathepsin L in vitro and in vivo. (1980) (89)
Cystatin A expression reduces bile salt-induced apoptosis in a rat hepatoma cell line. (1998) (88)
Structure, properties, mechanisms, and assays of cysteine protease inhibitors: cystatins and E-64 derivatives. (1995) (88)
Loss of Pten, a tumor suppressor, causes the strong inhibition of autophagy without affecting LC3 lipidation (2008) (87)
A Lysosomal Proteinase, the Late Infantile Neuronal Ceroid Lipofuscinosis Gene (CLN2) Product, Is Essential for Degradation of a Hydrophobic Protein, the Subunit c of ATP Synthase (1999) (87)
Molecular weight-dependent effects of hyaluronate on the arthritic synovium. (1998) (86)
Molecular cloning of human ornithine aminotransferase mRNA. (1986) (86)
Molecular Characterization of Mammalian Homologues of Class C Vps Proteins That Interact with Syntaxin-7* (2001) (84)
Membrane markers of endoplasmic reticulum preserved in autophagic vacuolar membranes isolated from leupeptin-administered rat liver. (1991) (83)
The crystal structure of human Atg4b, a processing and de-conjugating enzyme for autophagosome-forming modifiers. (2006) (83)
Phosholipase C-Related Inactive Protein Is Involved in Trafficking of γ2 Subunit-Containing GABAA Receptors to the Cell Surface (2007) (83)
Consideration about negative controls for LC3 and expression vectors for four colored fluorescent protein-LC3 negative controls (2008) (83)
Lysosomal cysteine and aspartic proteinases, acid phosphatase, and an endogenous cysteine proteinase inhibitor, cystatin-beta, in rat osteoclasts. (1993) (83)
Gene regulation and extracellular functions of procathepsin L. (1998) (82)
Different tissue distributions of two types of thiol proteinase inhibitors from rat liver and epidermis. (1984) (81)
Characterization of Cln3p, the gene product responsible for juvenile neuronal ceroid lipofuscinosis, as a lysosomal integral membrane glycoprotein (2003) (77)
Selective localization of Bcl-2 to the inner mitochondrial and smooth endoplasmic reticulum membranes in mammalian cells (2000) (76)
An ultrastructural and immunohistochemical study of PC12 cells during apoptosis induced by serum deprivation with special reference to autophagy and lysosomal cathepsins. (1998) (73)
Abnormal distribution of cathepsin proteinases and endogenous inhibitors (cystatins) in the hippocampus of patients with Alzheimer's disease, parkinsonism-dementia complex on Guam, and senile dementia and in the aged (2005) (68)
Neuronal Ceroid Lipofuscinosis: A Common Pathway? (2007) (68)
Alzheimer's disease amyloid beta-clipping enzyme (APP secretase): identification, purification, and characterization of the enzyme. (1991) (67)
Interaction of Doc2 with tctex-1, a Light Chain of Cytoplasmic Dynein (1998) (67)
Autophagic Compartments Gain Access to the MHC Class II Compartments in Thymic Epithelium (2009) (67)
Molecular cloning of cDNA for rat cathepsin C. Cathepsin C, a cysteine proteinase with an extremely long propeptide. (1991) (66)
Characterization of endopeptidase activity of tripeptidyl peptidase-I/CLN2 protein which is deficient in classical late infantile neuronal ceroid lipofuscinosis. (2000) (65)
Abnormal expression of lysosomal cysteine proteinases in muscle wasting diseases. (1987) (64)
Selective modulation of the secretion of proteinases and their inhibitors by growth factors in cultured differentiated podocytes. (2002) (63)
Amino acid sequence of rat liver thiol proteinase inhibitor. (1983) (62)
Cathepsin L activity is increased in alveolar macrophages and bronchoalveolar lavage fluid of smokers. (1993) (61)
Atg8L/Apg8L is the fourth mammalian modifier of mammalian Atg8 conjugation mediated by human Atg4B, Atg7 and Atg3 (2006) (61)
Participation of autophagy in the initiation of graft dysfunction after rat liver transplantation (2009) (60)
Postictal Blockade of Ischemic Hippocampal Neuronal Death in Primates Using Selective Cathepsin Inhibitors (1999) (59)
Processing of cathepsins L, B and D in psoriatic epidermis (1997) (59)
Tripeptidyl peptidase I, the late infantile neuronal ceroid lipofuscinosis gene product, initiates the lysosomal degradation of subunit c of ATP synthase. (2000) (59)
Amino acid sequence of rat epidermal thiol proteinase inhibitor. (1984) (58)
Deimination of 70-kD Nuclear Protein During Epidermal Apoptotic Events In Vitro (1998) (58)
Different immunolocalizations of cathepsins B, H, and L in the liver. (1985) (57)
Solution structure and dynamics of Ufm1, a ubiquitin-fold modifier 1. (2006) (56)
Immunocytochemical localization of prorenin, renin, and cathepsins B, H, and L in juxtaglomerular cells of rat kidney. (1989) (54)
Role for Gingipains in Porphyromonas gingivalis Traffic to Phagolysosomes and Survival in Human Aortic Endothelial Cells (2007) (53)
Autolysosomal Membrane-associated Betaine Homocysteine Methyltransferase (1999) (52)
Dynamic changes of cathepsins B and L expression in the monkey hippocampus after transient ischemia. (1996) (52)
Cytoplasmic processing of human profilaggrin by active mu-calpain. (1997) (52)
CELL AND TISSUE DISTRIBUTION OF LYSOSOMAL CYSTEINE PROTEINASES, CATHEPSINS B, H, AND L, AND THEIR BIOLOGICAL ROLES (1994) (51)
A new enzyme that specifically inactivates apo-protein of pyridoxal enzymes. (1971) (51)
Dendrin Location in Podocytes Is Associated with Disease Progression in Animal and Human Glomerulopathy (2011) (48)
Cloning and characterization of two neural‐salient serine/arginine‐rich (NSSR) proteins involved in the regulation of alternative splicing in neurones (1999) (48)
Processing and transport of the precursor of cathepsin C during its transfer into lysosomes. (1993) (47)
Purification and properties of proteinase B from yeast. (1981) (47)
Immunocytochemical localization of cathepsins B, H, and their endogenous inhibitor, cystatin beta, in islet endocrine cells of rat pancreas. (1988) (47)
Purification and characterization of thiol proteinase inhibitor from rat liver. (1982) (45)
Multiple processing of procathepsin L to cathepsin L in vivo. (1998) (45)
Preoviposition activation of cathepsin-like proteinases in degenerating ovarian follicles of the mosquito Culex pipiens pallens. (2001) (45)
Properties of a specific protease for pyridoxal enzymes and its biological role. (1972) (44)
PARK2/Parkin-mediated mitochondrial clearance contributes to proteasome activation during slow-twitch muscle atrophy via NFE2L1 nuclear translocation (2014) (43)
Calpain and cathepsins in the skeletal muscle of inflammatory myopathies. (1997) (43)
Abnormal increases of lysosomal cysteinine proteinases in rimmed vacuoles in the skeletal muscle. (1986) (42)
Activation of the intramyofibral autophagic-lysosomal system in muscular dystrophy. (1987) (41)
Mammalian Apg12p, but not the Apg12p.Apg5p conjugate, facilitates LC3 processing. (2002) (41)
Cysteine proteinases in bronchoalveolar epithelial cells and lavage fluid of rat lung. (1991) (40)
LC3/ a mammalian homolog of yeast Apg8p, is localized in autophagosome membranes after processing (2013) (40)
Inhibitions of cathepsin B and cathepsin L by E-64 in vivo. II. Incorporation of [3H]E-64 into rat liver lysosomes in vivo. (1982) (40)
The primary structure and tissue distribution of cathepsin C. (1992) (39)
Comprehensive proteomics analysis of autophagy-deficient mouse liver. (2008) (38)
Inhibitions of degradation of rat liver aldolase and lactic dehydrogenase by N-[N-(L-3-trans-carboxyoxirane-2-carbonyl)-L-leucyl] agmatine or leupeptin in vivo. (1980) (37)
Crystal structure of Ufc1, the Ufm1-conjugating enzyme. (2007) (36)
Specific Delay in the Degradation of Mitochondrial ATP Synthase Subunit c in Late Infantile Neuronal Ceroid Lipofuscinosis Is Derived from Cellular Proteolytic Dysfunction Rather than Structural Alteration of Subunit c (1996) (36)
Abnormal degradative pathway of mitochondrial ATP synthase subunit c in late infantile neuronal ceroid-lipofuscinosis (Batten disease). (1995) (36)
Three forms of thiol proteinase inhibitor from rat liver formed depending on the oxidation-reduction state of a sulfhydryl group. (1984) (36)
An immunocytochemical study on co-localization of cathepsin B and atrial natriuretic peptides in secretory granules of atrial myoendocrine cells of rat heart. (1989) (35)
Immunocytochemical localization of cathepsins B, H, L, and T4 in follicular cells of rat thyroid gland. (1989) (35)
Primate neurons show different vulnerability to transient ischemia and response to cathepsin inhibition (2002) (35)
A new enzyme that specifically inactivates apo-protein of NAD-dependent dehydrogenases. (1971) (34)
Analysis of where and which types of proteinases participate in lysosomal proteinase processing using bafilomycin A1 and Helicobacter pylori Vac A toxin. (1999) (34)
Lysosomal Turnover of GABARAP-Phospholipid Conjugate is Activated During Differentiation of C2C12 Cells to Myotubes without Inactivation of the mTor Kinase-Signaling Pathway (2006) (34)
The expression of tripeptidyl peptidase I in various tissues of rats and mice. (2002) (33)
Mutation of the glycosylated asparagine residue 286 in human CLN2 protein results in loss of enzymatic activity. (2004) (33)
Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356 (2016) (33)
Immunohistochemical characterization of the intracellular pool of water channel aquaporin-2 in the rat kidney (2002) (33)
The Intracellular Location and Function Of Proteins Of Neuronal Ceroid Lipofuscinoses (2004) (33)
Changes of proteasomes and cathepsins activities and their expression during differentiation of C2C12 myoblasts. (1995) (32)
Cysteine proteinases in rat parathyroid cells with special reference to their correlation with parathyroid hormone (PTH) in storage granules. (1993) (32)
Gene structure and 5'‐upstream sequence of rat cathepsin L (1989) (32)
The substrate specificity of proteinase B from baker's yeast. (1981) (32)
Cathepsin B and D expression in squamous cell carcinoma (1996) (32)
Participation of cathepsins B, H, and L in perikaryal condensation of CA1 pyramidal neurons undergoing apoptosis after brief ischemia. (1996) (32)
Editorial :Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). DOI: 10.1080/15548627.2015.1100356;WOS:000373595400001; 2-s2.0-85013763791&;PMID: 26799652 (2016) (31)
Lysosomal cysteine proteinases in rat epididymis. (1994) (31)
Increases in cathepsins B and L and thiol proteinase inhibitor in muscle of dystrophic hamsters. Their localization in invading phagocytes. (1984) (31)
Effect of starvation and refeeding on autophagy and heterophagy in rat liver. (1986) (31)
Characterization of CAA0225, a novel inhibitor specific for cathepsin L, as a probe for autophagic proteolysis. (2009) (31)
Molecular basis of intracellular regulation of thiol proteinase inhibitors. (1985) (30)
Sulfhydryl oxidase (SOx) from mouse epidermis: molecular cloning, nucleotide sequence, and expression of recombinant protein in the cultured cells. (2002) (29)
CDK5 regulates cell–cell and cell–matrix adhesion in human keratinocytes (2005) (29)
Cysteine proteinases in GH4C1 cells, a rat pituitary tumor cell line, are secreted by the constitutive and regulated secretory pathways. (1995) (29)
Specific localization of lysosomal aminopeptidases in type II alveolar epithelial cells of the rat lung. (2001) (29)
Involvement of interleukin-6 in activation of lysosomal cathepsin and atrophy of muscle fibers induced by intramuscular injection of turpentine oil in mice. (1997) (28)
Monoubiquitylation of GGA3 by hVPS18 regulates its ubiquitin-binding ability. (2006) (28)
Proenzyme from of cathepsin L produced by thymic epithelial cells promotes proliferation of immature thymocytes in the presence of IL-1, IL-7, and anti-CD3 antibody. (1993) (27)
The antigen presentation pathway in medullary thymic epithelial cells, but not that in cortical thymic epithelial cells, conforms to the endocytic pathway (1998) (27)
Gene structure of rat cathepsin H (1989) (27)
Murine Apg12p has a substrate preference for murine Apg7p over three Apg8p homologs. (2002) (27)
Immunocytochemical localization of cathepsins B and H in corticotrophs and melanotrophs of rat pituitary gland. (1990) (26)
Generation of both MHC class I‐ and class II‐restricted antigenic peptides from exogenously added ovalbumin in murine phagosomes (2000) (26)
Egr family member proteins are involved in the activation of the cathepsin L gene in v-src-transformed cells. (1997) (26)
Autodegradation of lysosomal cysteine proteinases. (1987) (26)
Expression of cathepsin D and B in invasion and metastasis of squamous cell carcinoma (1997) (25)
Visual impairment and REP-1 gene mutations in Japanese choroideremia patients. (1999) (25)
Differences in expression patterns of cathepsin C/dipeptidyl peptidase I in normal, pathological and aged mouse central nervous system (2013) (25)
Leupeptin-induced appearance of partial fragment of betaine homocysteine methyltransferase during autophagic maturation in rat hepatocytes. (2001) (24)
Endogenous thiol protease inhibitor from rat liver. (1981) (24)
Developmental changes in the expression of neuronal ceroid lipofuscinoses-linked proteins. (2000) (23)
Crystallization and properties of human liver ornithine aminotransferase. (1982) (23)
Changes of lysosomal proteinase activities and their expression in rat cultured keratinocytes during differentiation. (1991) (22)
Studies of new intracellular proteases in various organs of rats. Participation of proteases in degradation of ornithine aminotransferase in vitro and in vivo. (1976) (22)
Differentiation-specific expression and localization of an autophagosomal marker protein (LC3) in human epidermal keratinocytes. (2008) (21)
Distributions and localizations of lysosomal cysteine proteinases and cystatins (1986) (21)
Neuronal Ceroid‐Lipofuscinosis ‐ Late‐Infantile or Jansky‐Bielschowsky Type ‐ Revisited (1996) (21)
Identification of mouse Vps16 and biochemical characterization of mammalian class C Vps complex. (2003) (21)
Total synthesis of the cystatin α gene and its expression in E. coli (1988) (20)
Inhibition of cathepsin L-induced degradation of epidermal growth factor receptors by c-Ha-ras gene products. (1988) (20)
Mechanism and regulation of lysosomal sequestration and proteolysis. (1991) (20)
Immunocytochemical localization of angiotensinogen and cathepsins B, H, and L in rat hepatocytes, with special reference to degradation of angiotensinogen in lysosomes after colchicine. (1989) (19)
Immunological studies on cathepsins B and H from rat liver. (1982) (19)
Metabolic contribution of hepatic autophagic proteolysis: old wine in new bottles. (2012) (19)
Function of the propeptide region in recombinant expression of active procathepsin L in Escherichia coli. (1999) (19)
Enrichment of GABARAP Relative to LC3 in the Axonal Initial Segments of Neurons (2013) (19)
Mechanism of postmortem autolysis of skeletal muscle. (1984) (18)
Immunocytochemical localization of cathepsin B in rat anterior pituitary endocrine cells, with special reference to its co-localization with renin and prorenin in gonadotrophs. (1991) (18)
Immunocytochemical localization of lysosomal cysteine and aspartic proteinases, and ubiquitin in rat epidermis. (1997) (18)
A novel type of E 3-ligase for the Ufm 1-conjugation system (2009) (18)
Comparison of properties of thiol proteinase inhibitors from rat serum and liver. (1982) (17)
CLIP‐derived self peptides bound to MHC class II molecules of medullary thymic epithelial cells differ from those of cortical thymic epithelial cells in their diversity, length, and C‐terminal processing (2000) (17)
Inflammatory response and cathepsins in silica‐exposed Hermansky–Pudlak syndrome model pale ear mice (2004) (17)
Effect of metabolic alterations on the density and the contents of cathepsins B, H and L of lysosomes in rat macrophages. (1990) (16)
Concept on mechanism and regulation of intracellular enzyme degradation in mammalian tissues. (1976) (16)
Cysteine proteinases in rat dorsal root ganglion and spinal cord, with special reference to the co-localization of these enzymes with calcitonin gene-related peptide in lysosomes (1993) (16)
Overexpression of cation-dependent mannose 6-phosphate receptor prevents cell death induced by serum deprivation in PC12 cells. (1998) (16)
Mode of action of specific inactivating enzymes for pyridoxal enzymes and NAD-dependent enzymes and their biological significance. (1972) (15)
Peroxisome degradation in mammals (2011) (15)
Extinction of Organelles in Differentiating Epidermis (1999) (15)
Myosin in hepatocytes is essential for bile canalicular contraction. (2008) (15)
Changes in the distribution and density of caveolin 3 molecules at the plasma membrane of mdx mouse skeletal muscles: a fracture-label electron microscopic study (2002) (15)
Expression of cathepsin H in differentiating rat spermatids: immunoelectron microscopic study (2003) (15)
Changes in immunoreactivity for cathepsin H in rat type II alveolar epithelial cells and its proteolytic activity in bronchoalveolar lavage fluid over 24 hours (1991) (15)
A family with adult type ceroid lipofuscinosis (Kufs' disease) and heart muscle disease: report of two autopsy cases. (1995) (15)
Regulation of intracellular enzyme levels by group specific proteases in various organs. (1973) (15)
Neuronal ceroid lipofuscinosis: late infantile or Janský Bielschowsky type – re-revisited (2001) (15)
Formation of mixed disulfide of cystatin-beta in cultured macrophages treated with various oxidants. (1987) (15)
Autocatalytic inactivation of lysosomal cathepsins is associated with inhibition of protein breakdown by insulin-like growth factor-1 (IGF-1) in myotubes. (1995) (14)
Phalloidin-induced accumulation of myosin in rat hepatocytes is caused by suppression of autolysosome formation. (1990) (14)
Molecular cloning and sequencing of cDNA for rat cystatin β (1990) (14)
Immunocytochemical localization of a cysteine protease in adult worms of the liver flukeFasciola sp. (2004) (14)
Structural organization of the gene encoding rat cystatin beta. (1992) (14)
Doxorubicin-induced glomerulosclerosis with proteinuria in GFP-GABARAP transgenic mice. (2012) (14)
Cytochemical localization of hyaluronic acid in human synovium with special reference to its possible process of degradation. (1995) (14)
Role of cathepsin B as prorenin processing enzyme in human kidney. (1995) (14)
The carboxyl terminal 17 amino acids within Apg7 are essential for Apg8 lipidation, but not for Apg12 conjugation (2003) (13)
Variations in immunoreactivity of angiotensinogen and cathepsins B and H in rat hepatocytes over 24 hours. (1990) (13)
Proteolytic modification of rat liver fructose-1,6-bisphosphate aldolase by administration of leupeptin in vivo. (1981) (13)
Coexistence of renin and cathepsin B in secretory granules of granular duct cells in male mouse submandibular gland. (1993) (13)
Immunolocalization of cathepsins B, H and L in skeletal muscle of X-linked muscular dystrophy (mdx) mouse (2004) (13)
Decreased lysosomal subunit c-degrading activity in fibroblasts from patients with late infantile neuronal ceroid lipofuscinosis. (1997) (12)
Changes in subcellular structures of parietal cells in the rat gastric gland after omeprazole. (1992) (12)
Proteinases participating in the processing and activation of prolegumain in primary cultured rat macrophages (2004) (12)
Integrity of the cytoskeletal system is important for phagocytosis by Kupffer cells. (2008) (12)
Lysosomal sequestration of cytosolic enzymes and lysosomal thiol cathepsins. (1985) (12)
A new factor from enteric bacteria of rats amplifying induction of liver enzyme by glucocorticoid. 1. Purification, properties and biological action. (1977) (12)
Immunocytochemical localization of cathepsins B and H in human pancreatic endocrine cells and insulinoma cells (2004) (12)
The induction of autophagic vacuoles and the unique endocytic compartments, C-shaped multivesicular bodies, in GH4C1 cells after treatment with 17beta-estradiol, insulin and EGF. (1999) (12)
Splenic cathepsin L is maturated from the proform by interferon-gamma after immunization with exogenous antigens. (2001) (11)
and targeting to autophagosomal membranes. (2004) (11)
Different functional share of individual lysosomal cathepsins in normal and pathological conditions. (1993) (11)
Pathological study on sibling autopsy cases of the late infantile form of neuronal ceroid lipofuscinosis (1999) (11)
Immunocytochemical localization of cathepsins B, H, and L in the rat gastro-duodenal mucosa (2004) (10)
Studies on new intracellular proteases in various organs of rat. 1. Purification and comparison of their properties. (1975) (10)
Physical association of Ras and cathepsins B and L in the conditioned medium of v-Ha-ras-transformed NIH3T3 cells. (1995) (10)
Variations in immunocytochemical localization of cathepsin B and thyroxine in follicular cells of the rat thyroid gland and plasma TSH concentrations over 24 hours (2004) (10)
Hepatic gap junctions in the hepatocarcinogen-resistant DRH rat (2008) (10)
Procathepsin L‐specific antibodies that recognize procathepsin L but not cathepsin L (1993) (10)
Studies on thiol proteinase inhibitors in rat peripheral blood cells. (1984) (10)
Method for monitoring pexophagy in mammalian cells. (2009) (9)
Blocking LC3 lipidation and ATG12 conjugation reactions by ATG7 mutant protein containing C572S. (2019) (9)
Gyrate atrophy of the choroid and retina: decreased ornithine aminotransferase concentration in cultured skin fibroblasts from patients. (1984) (9)
MHC Class I Presentation of an Exogenous Polypeptide Antigen Encoded by the Murine AIDS Defective Virus (1997) (9)
Suppression of lysosomal proteolysis at three different steps in regenerating rat liver. (1998) (8)
Genomic structure and PCR-SSCP analysis of the human CD40 ligand gene: Its application to prenatal screening for X-linked hyper-IgM syndrome (1996) (8)
Accumulation of mitochondrial ATP synthase subunit c in muscle in a patient with neuronal ceroid lipofuscinosis (late infantile form) (1997) (8)
Efficient Mitochondrial Import of Newly Synthesized Ornithine Transcarbamylase (OTC) and Correction of Secondary Metabolic Alterations in spfash Mice following Gene Therapy of OTC Deficiency (1999) (8)
Human osteoarthritic cartilage exhibits the 2B6 epitope without pretreatment with chondroitinase ABC. (1996) (8)
Gene structures of rat cathepsins H and L. (1991) (8)
Transformation of leukotriene D4 catalyzed by lysosomal cathepsin H of rat liver. (1983) (8)
Expression of cysteine proteinases and their inhibitor, cystatin beta, in cultured rat mesangial cells. (1998) (8)
Rat liver thiol proteinases: cathepsin B, cathepsin H and cathepsin L. (1981) (7)
Defect of proteolysis of mitochondrial ATP synthase subunit C in neuronal ceroid lipofuscinosis. (1995) (7)
Precursor of rat epidermal cathepsin L: purification and immunohistochemical localization. (2000) (7)
Functional shares of cathepsins B, H and L in autophagy and heterophagy (1986) (7)
Lysosomal cysteine and aspartic proteinases and ubiquitin in rat and human urinary bladder epithelium. (1996) (7)
Autophagy Regulates Lipid Droplet Formation and Adipogenesis (2013) (7)
Lysosomal thiol cathepsins and their endogenous inhibitors. Distribution and localization. (1985) (7)
A new sensitive and convenient assay of ornithine aminotransferase. (1983) (7)
Localization of Cathepsins B, D, L, LAMP-1 and μ-Calpain in Developing Hair Follicles (2001) (7)
Regulatory Mechanism of Enzyme Catabolism (1972) (7)
Morphological studies on CLN2. (2001) (6)
Properties of fructose-1,6-bisphosphate aldolase inactivating enzymes in rat liver lysosomes. (1981) (6)
Enteric flora and mammalian enzyme induction. (1970) (6)
Assembly of hair keratins in transfected epithelial cells. (1996) (6)
Design and synthesis of cathepsin B inhibitors by an affinity labeling approach. (1988) (6)
Immunohistochemical Demonstration of Cathepsins B and L in the Periodontal Ligament (PDL) of the Rat Molar (2001) (5)
Enzyme immunoassay of medullasin in peripheral blood. (1988) (5)
[Batten disease]. (1998) (5)
Cysteine proteinase-inhibitory activity of ras gene product is not affected by mutations at GTPase-activating protein-binding sites. (1989) (5)
Muscle fiber degradation in distal myopathy with rimmed vacuoles (1994) (5)
New insight into lysosomal protein storage disease: Delayed catabolism of ATP synthase subunit c in batten disease (1995) (5)
In Vitro Assays of Lipidation of Mammalian Atg8 Homologs (2014) (5)
Changes in proteinase activities during the differentiation of murine erythroleukemia cells. (1990) (5)
Molecular cloning and sequencing of cDNA for rat cystatin beta. (1990) (4)
Genomic structure of human cystatin A. (1997) (4)
Proteolysis in milk and dairy products (1982) (4)
[Autophagic-lysosomal system: physiology and pathology]. (2006) (4)
Intracellular protein catabolism and new serine proteases. (1977) (4)
Degradation of myelin proteins by cathepsin B and inhibition by E-64 analogue (1984) (4)
Endogenous thiol proteinase inhibitor from rat liver. (1982) (3)
Modification of rat liver fructose biphosphate aldolase by lysosomal proteinases. (1982) (3)
Apoptosis of the CA1 pyramidal neurons in gerbil hippocampus following transient ischemia (1994) (3)
STRUCTURES AND BIOLOGICAL FUNCTIONS OF CATHEPSIN B AND L (1981) (3)
Involvement of thiol proteases in galactosialidosis. (1986) (3)
Co-localization of ras gene products and cathepsin L in cytoplasmic vesicles in v-Ha-ras-transformed NIH3T3 mouse fibroblasts. (1991) (3)
6 – Regulation of Inhibitory Activity of Cysteine Proteinase Inhibitor (Cystatin β) by Glutathione Mediated Covalent Modification (1989) (2)
The interaction of mammalian Class C Vps with nSec-1/Munc18-a and syntaxin 1A regulates pre-synaptic release. (2006) (2)
Molecular basis of lysosomal accumulation of subunit c of mitochondrial ATP synthase in neuronal ceroid-lipofuscinosis (1993) (2)
Prevention of apoptosis of mammalian cells by the CED-3-cleaved form of CED-9. (2001) (2)
Partial characterization of a rabbit liver Ca(2+)-calmodulin-dependent kinase with myosin light chain phosphorylating activity. (1993) (2)
Lysosomal Proteinosis Based on Decreased Degration of a Specific Protein, Mitochondrial ATP Synthase Subunit C (1996) (2)
Cysteine protease inhibitors with S-(3-nitro-2-pyridinesulfenyl)-cysteine residue in affinity analogs of peptide substrates. (1989) (2)
Letter to the Editor: 1H, 13C, and 15N Resonance Assignments of Human Microtubule-associated Protein Light Chain-3 (2004) (1)
Immunohistochemical localization of lysosomal cysteine protease cathepsins B and L in monkey hippocampal neurons after transient ischemia (1999) (1)
Molecular genetics of gyrate atrophy. (1987) (1)
Lysosomal proteinosis based on decreased degradation of a specific protein, mitochondrial ATP synthase subunit C: Batten disease. (1996) (1)
Crystal Structure of the Ufc1, Ufm1 conjugating enzyme 1 (2007) (1)
Strategy for neuroprotection based on “calpain-cathepsin hypothesis” (1998) (1)
List of Key Words (1995) (1)
Inhibition of Autophagy Prevents Hippocampal Pyramidal Neuron Death after Hypoxic-lschemic Injury. Commentary (2008) (1)
Immunocytochemical localization of cathepsins B, H, and L in the rat gastro-duodenal mucosa (2004) (1)
[Molecular genetics of gyrate atrophy]. (1988) (1)
Solution structure of microtubule-associated protein light chain-3 (2004) (1)
Inductions of cathepsins b and h and cystatins alpha and beta within macrophages in various human diseases an immunohistochemical study (1988) (0)
Aging, Diseases and Sports from the Aspect of Cell Clearance System, Autophagy (2010) (0)
6 The Expression and Structure of Rat Cystatin ß Gene (1994) (0)
[Advances in the study on endogenous cysteine proteinase inhibitor family]. (1986) (0)
Epitheliumthe MHC Class II Compartments in Thymic Autophagic Compartments Gain Access to (2009) (0)
Title Page / Table of Contents, Supplement 2, 1995 (1995) (0)
Lysosomal cysteine proteinases (cathepsins B.H. and L) and the endogenous inhibitors (Cystatins a and b) in the skeletal muscles in various neuromuscular diseases (1994) (0)
Proteasomes are involved in keratinocyte differentiation (1994) (0)
Crystal Structure of LC3-p62 complex (2008) (0)
CHLOROQUINE-INDUCED CHANGES IN BRAIN AND SKIN MIMIC NEURONAL CEROID-LIPOFUSCINOSIS (NCL) (1999) (0)
Communication Developmental neuroscience Degeneration and regenerationChanges in immunoreactivity for ubiquitin and heat shock proteins in the gerbil hippocampus following trangent ischemia (1992) (0)
[Batten disease (Neuronal ceroid lipofuscinoses)--accumulation of ATP synthase subunit c caused by the delay of lysosomal degradation]. (1995) (0)
Immunohistochemical Periodontal (2018) (0)
Total synthesis of the cystatin alpha gene and its expression in E. coli. (1988) (0)
[Interaction of cysteine proteinase inhibitor with glutathione]. (1988) (0)
Localization of cysteine proteinases and their activities in the developing rat spinal cord (1992) (0)
1307 In situ cytochemical detection of DNA fragmentation in the Ca1 pyramidal neurons following transient ischemia (1993) (0)
[Biological meaning of intracellular proteinase inhibitors]. (1989) (0)
Solution Structure of Ufm1, a ubiquitin-fold modifier (2006) (0)
DeathMultiple Pathways of TWEAK-Induced Cell (2001) (0)
Contents Vol. 33, 2011 (2011) (0)
Changes in immunoreactivity for cysteine proteinases in the gerbil hippocampus following transient ischemia (1991) (0)
Electron microscopical and immunohistochemical studies on the localization of cathepsin B, D, L, LAMP-1 and μ-calpain in developing hair follicles (2002) (0)
Structure of human Atg4b (2006) (0)
Potentiation of cysteine proteinase-inhibitor activity of full-length Ha-ras oncogene products by denaturation-renaturation. (1989) (0)
Communication Mutation of the glycosylated asparagine residue 286 in human CLN2 protein results in loss of enz ymatic activity (2004) (0)
[The endosomal-lysosomal system: new roles in protein degradation]. (1997) (0)
Modes of proteolysis of cystathionase and ornithine aminotransferase by serine protease from the rat small intestine. (1978) (0)
Immunocytochemical Localization of Lysosomal Cysteine Proteinases in Rat Endocrine Pancreas (1988) (0)
Cystatin A expression reduces bile salt-induced apoptosis in a rat hepatoma cell line. (1998) (0)
166 Genomic analysis of human cystatin A (1997) (0)
Immunocytochemical localization of cysteine proteinases and calcitonin gene-related peptide (CGRP) in nerve cells of rat spinal cord and spinal ganglion (1991) (0)
[Inborn errors of lysosome protease]. (1988) (0)
Immunocytochemical Localization of Angiotensinogen in Rat Hepatocytes (1988) (0)
Inhibition of cathepsin B by cystatin a reduces bile salt- but not staurosporine-induced apoptosis in a rat hepatoma cell line* (1998) (0)
[Autophagy and neurodegenerative diseases]. (2006) (0)
Detection of type VII collagen gene mutations in dystrophic froms of epidermolysis bullosa patients by PCR-SSCP and PCR-RFLP analyses (1993) (0)
Intracellular functions of lysosomal cysteine proteinases in macrophages. (1992) (0)
Upon Activation of CD 4 CTLA-4 by Secretion of CTLA-4-Containing Regulation of Cell Surface Expression of Kominami , Takehiko Fujisawa and (2000) (0)
TWEAK-Induced Cell Death Mediates Multiple Pathways of Fibroblast Growth Factor-Inducible 14 (2002) (0)
[Development of the application of enzyme immunoassay for cathepsins]. (1987) (0)
P-10 Localization of Cathepsin B and μ Calpain in Hair Follicles of Neonatal Rats. : (2001) (0)
1111 Lysosomal cysteine proteinases appearing in the processes of neuronal death during the early stage of cervical spinal cord of chick embryos (1993) (0)

This paper list is powered by the following services:

What Schools Are Affiliated With Eiki Kominami?

Eiki Kominami is affiliated with the following schools:

Juntendo University