E. Miles Vaughan Williams
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Pharmacology
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E. Miles Vaughan Williams's Degrees
- Bachelors Biology University of Oxford
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(Suggest an Edit or Addition)E. Miles Vaughan Williams's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- A Classification of Antiarrhythmic Actions Reassessed After a Decade of New Drugs (1984) (587)
- The effect of amiodarone, a new anti‐anginal drug, on cardiac muscle (1970) (555)
- A third class of anti‐arrhythmic action. Effects on atrial and ventricular intracellular potentials, and other pharmacological actions on cardiac muscle, of MJ 1999 and AH 3474 (1970) (388)
- Small‐nerve junctional potentials. The distribution of small motor nerves to frog skeletal muscle, and the membrane characteristics of the fibres they innervate * (1953) (333)
- Properties of the ‘slow’ skeletal muscle fibres of the frog * (1953) (293)
- THE EFFECTS ON CARDIAC MUSCLE OF β‐RECEPTOR ANTAGONISTS IN RELATION TO THEIR ACTIVITY AS LOCAL ANAESTHETICS (1965) (248)
- The effect of altered thyroid state on atrial intracellular potentials (1970) (213)
- Effect of Altering Potassium Concentration on the Action of Lidocaine and Diphenylhydantoin on Rabbit Atrial and Ventricular Muscle (1971) (198)
- Mode of action of beta receptor antagonists on cardiac muscle. (1966) (126)
- The effects of acetylcholine in the heart‐lung preparation including the production of auricular fibrillation (1955) (100)
- EFFECTS ON RABBIT NODAL, ATRIAL, VENTRICULAR AND PURKINJE CELL POTENTIALS OF A NEW ANTIARRHYTHMIC DRUG, CIBENZOLINE, WHICH PROTECTS AGAINST ACTION POTENTIAL SHORTENING IN HYPOXIA (1982) (92)
- Investigations of the mode of action of a new antidysrhythmic drug, Kö 1173 (1972) (90)
- The relevance of β‐receptor blockade to ouabain‐induced cardiac arrhythmias (1969) (89)
- The mode of action of quinidine on isolated rabbit atria interpreted from intracellular potential records. (1958) (88)
- Prevention of arrhythmias due to cardiac glycosides by block of sympathetic beta receptors. (1963) (84)
- A comparison of the anti‐arrhythmic actions of I.C.I. 50172 and (—)‐propranolol and their effects on intracellular cardiac action potentials and other features of cardiac function (1969) (78)
- Characterization of a new oral antiarrhythmic drug, flecainide (R818) (1981) (76)
- The effects of prolonged beta-adrenoceptor blockade on heart weight and cardiac intracellular potentials in rabbits. (1975) (71)
- Subgroups of class 1 antiarrhythmic drugs. (1984) (65)
- The individual effects of CO2, bicarbonate and pH on the electrical and mechanical activity of isolated rabbit auricles (1955) (61)
- Classifying Antiarrhythmic Actions: By Facts or Speculation (1992) (59)
- A comparison of tests for antifibrillatory action. (1961) (58)
- Classification of Antiarrhythmic Actions (1989) (57)
- Local Anæsthetic Activity of the β-Receptor Antagonist, Pronethalol (1964) (56)
- Cardiospecificity of -receptor blockade. A comparison of the relative potencies on cardiac and peripheral vascular -adrenoceptors of propranolol, of practolol and its ortho-substituted isomer, and of oxprenolol and its para-substituted isomer. (1973) (56)
- Pacemaker selectivity: influence on rabbit atria of ionic environment and of alinidine, a possible anion antagonist. (1981) (54)
- Chemosensitivity of cardiac muscle (1967) (53)
- Histamine Release and Intracellular Potentials During Anaphylaxis in the Isolated Heart (1960) (51)
- Loss of cellular potassium as a cause of intestinal paralysis in dogs (1952) (51)
- Significance of Classifying Antiarrhythmic Actions Since the Cardiac Arrhythmia Suppression Trial (1991) (49)
- Antifibrillatory action (1962) (47)
- Some observations concerning the mode of action of acetylcholine in isolated rabbit atria (1958) (47)
- Electrophysiological effects of α‐adrenoceptor antagonists in rabbit sino‐atrial node, cardiac Purkinje cells and papillary muscles (1984) (44)
- The effect of bretylium on intracellular cardiac action potentials in relation to its anti‐arrhythmic and local anaesthetic activity (1969) (44)
- INVESTIGATIONS TO CHARACTERIZE A NEW ANTI‐ARRHYTHMIC DRUG, ORG 6001, INCLUDING A SIMPLE TEST FOR CALCIUM ANTAGONISM (1976) (43)
- Adaptation of hypertensives to treatment with cardioselective and non-selective beta-blockers. Absence of correlation between bradycardia and blood pressure control, and reduction in slope of the QT/RR relation. (1980) (42)
- Pacemaker potentials. The excitation of isolated rabbit auricles by acetylcholine at low temperatures (1956) (40)
- THE MODE OF ACTION OF DRUGS UPON INTESTINAL MOTILITY (1954) (38)
- Local anaesthetic and anti‐arrhythmic actions of alprenolol relative to its effect on intracellular potentials and other properties of isolated cardiac muscle (1970) (37)
- Effects on cardiac muscle of the β‐adrenoceptor blocking drugs INPEA and LB46 in relation to their local anaesthetic action on nerve (1971) (34)
- The effect of changes in extracellular potassium concentration on the intracellular potentials of isolated rabbit atria (1959) (32)
- QT and action potential duration. (1982) (31)
- MORPHOMETRIC CHANGES IN RABBIT VENTRICULAR MYOCARDIUM PRODUCED BY LONG-TERM BETA-ADRENOCEPTOR BLOCKADE (1977) (28)
- The effect of prolonged propranolol administration on myocardial transmural capillary density in young rabbits. (1981) (27)
- Delayed ventricular repolarization as an anti-arrhythmic principle. (1985) (25)
- The experimental basis for the choice of an anti-arrhythmic drug. (1970) (24)
- The effects of various fatty acids on action potential shortening during sequential periods of ischaemia and reperfusion. (1980) (24)
- The formation of acetylcholine in the heart; its effect on the systemic output and its importance for auricular fibrillation caused by aconitine (1956) (23)
- Intracellular Na and K concentrations of rabbit atria, in relation to the action of quinidine (1962) (22)
- Electrophysiological and Cardiovascular Effects of Pirmenol, a New Class 1 Antiarrhythmic Drug (1986) (21)
- Electrophysiological basis for a rational approach to antidysrhythmic drug therapy. (1974) (21)
- A study of intracellular potentials and contractions in atria, including evidence for an after‐potential (1959) (20)
- ANION ANTAGONISM—A FIFTH CLASS OF ANTIARRHYTHMIC ACTION? (1981) (20)
- DIFFERENTIAL ACTIONS ON RABBIT NODAL, ATRIAL, PURKINJE CELL AND VENTRICULAR POTENTIALS OF MELPERONE, A BRADYCARDIC AGENT DELAYING REPOLARIZATION: EFFECTS OF HYPOXIA (1982) (20)
- Cardiovascular effects of bevantolol, a selective β1‐adrenoceptor antagonist with a novel pharmacological profile (1985) (19)
- Effect of prolonged beta-receptor blockade on dry weight and electrophysiological responses of rabbit hearts. (1974) (18)
- LOCAL ANAESTHETIC ACTIVITY OF THE BETA-RECEPTOR ANTAGONIST, PRONETHALOL. (1964) (18)
- The Effects of Indecainide, a New Antidysrhythmic Drug, on Nodal Tissues in the Isolated Rabbit Heart (1986) (18)
- Effects on rabbit cardiac potentials of aprindine and indecainide, a new antiarrhythmic agent, in normoxia and hypoxia (1985) (17)
- ADAPTATIONAL RESPONSES TO PROLONGED β‐ADRENOCEPTOR BLOCKADE IN ADULT RABBITS (1980) (17)
- THE PRODUCTION OF BLOCK AND AURICULAR FIBRILLATION IN THE HEART-LUNG PREPARATION BY INHIBITORS OF CHOLINESTERASE (1955) (17)
- Relevance of cellular to clinical electrophysiology in interpreting antiarrhythmic drug action (1989) (16)
- ELECTROPHYSIOLOGICAL AND OTHER EFFECTS ON RABBIT HEARTS OF CCI 22277, A NEW STEROIDAL ANTIARRHYTHMIC DRUG (1982) (16)
- The influence of intraluminal pressure upon the transport of fluid through cannulated Thiry‐Vella loops in dogs (1951) (16)
- EFFECT OF PROLONGED β‐ADRENOCEPTOR BLOCKADE ON HEART WEIGHT AND ULTRASTRUCTURE IN YOUNG RABBITS (1980) (15)
- The development of sensitivity to acetylcholine in denervated muscle (1949) (15)
- Inhibition and neuromuscular paralysis in Ascaris lumbricoides (1963) (15)
- The relevance of cellular to clinical electrophysiology in classifying antiarrhythmic actions. (1992) (14)
- The absence of effect of chemical sympathectomy on ventricular hypertrophy induced by hypoxia in young rabbits. (1983) (12)
- Effect of bicarbonate administration on skeletal muscle intracellular pH in the rat: implications for acute administration of bicarbonate in man. (1992) (12)
- Classification of the Antiarrhythmic Action of Moricizine (1991) (11)
- CENTRAL AND PERIPHERAL ACTIONS OF PRONETHALOL (1965) (11)
- Bevantolol: A Beta‐1 Adrenoceptor Antagonist with Unique Additional Actions (1987) (10)
- Relation of Extracellular to Intracellular Potential Records from Single Cardiac Muscle Fibres (1959) (10)
- Further studies regarding the structure activity relationships of β‐adrenoceptor antagonists (1973) (10)
- Simultaneous measurements of contractions and intracellular potentials in isolated rabbit atria exposed to acetylcholine (1959) (9)
- A SIMPLIFIED INTEGRATING LIGHT RECORDER FOR FIELD USE. (1943) (9)
- CENTRAL NERVOUS SYSTEM EFFECTS OF BETA ADRENERGIC BLOCKING DRUGS (1967) (9)
- The effect on intracellular atrial potentials of bretylium in relation to its local anaesthetic potency. (1969) (8)
- The effect of prolonged treatment with oxyfedrine on intracellular potentials and on other features of cardiac function in rabbits and guinea‐pigs (1973) (8)
- The effects of nadolol on various cardiac tissues in normoxia, and on atrial muscle in simulated ischaemia. (1982) (7)
- Na+/H+ and HCO3-/Cl- exchange in the control of intracellular pH in vivo in the spontaneously hypertensive rat. (1991) (6)
- Long-term effects of propranolol on tyrosine hydroxylase and dopamine-beta-hydroxylase in the superior cervical ganglia of the rabbit [proceedings]. (1976) (6)
- Further studies of alinidine induced bradycardia in the presence of caesium. (1986) (6)
- AN INEXPENSIVE INTEGRATING LIGHT RECORDER. (1941) (5)
- The action of posterior pituitary extracts upon propulsion in the small intestine of conscious dogs. (1952) (5)
- Is Phosphodiesterase Inhibition Arrhythmogenic? Electrophysiologic Effects in Pithed Rats and in Normoxic and Hypoxic Rabbit Atria of Enoximone, a New Cardiotonic Agent (1987) (5)
- Antiarrhythmic action of specific bradycardic agents (1987) (5)
- The action of quinidine interpreted from intracellular potentials of single cardiac fibres. (1958) (5)
- The effects on cardiac muscle and nerve of a fluorinated decahydroquinoline derivative, L7810, rapidly absorbed after oral administration (1973) (5)
- The effect on atrial and ventricular intracellular potentials, and other pharmacological actions of L9146, a non-halogenated benzo(b)thiophene related to amiodarone. (1977) (4)
- THE ACTION OF PRONETHALOL ON SPINAL REFLEXES (1965) (4)
- Urea excretion by rabbits (1946) (3)
- Control of Cardiac Rhythm (1998) (3)
- The development of new antidysrhythmic drugs. (1973) (3)
- Relief of postoperative pain and intestinal motility. (1950) (3)
- The mode of action of morphine upon the intestine. (1951) (3)
- A-V Block and Cardiac Output (1955) (2)
- The Action of Beta-Receptor Blocking Agents on Cardiac Muscle (1967) (2)
- Electrophysiological aspects of the action of antiarrhythmic drugs. (1969) (2)
- Disopyramide (1984) (1)
- The measurement of secretion and absorption by intestinal loops in conscious dogs. (1951) (1)
- Hypoxia‐induced cardiac hypertrophy in rabbits treated with verapamil and nifedipine (1983) (1)
- Calcium Currents Mediating Inotropic and Chronotropic Effects in Mammalian Cardiac Muscle (1980) (1)
- A vertical approach to cardiac arrhythmias (1986) (1)
- Adrenergic arrhythmogenicity. (1988) (1)
- Cellular basis of cardiac dysrhythmias. (1974) (0)
- Electrophysiological and other effects on cardiac function of KO 1173. (1973) (0)
- Antiarrhythmic Drug Development: Classification and its Impact on Development. (1995) (0)
- Effect of analgesics and of electrolyte changes on intestinal motility. (1956) (0)
- Adaptation ofhypertensives totreatmentwith cardioselective andnon-selective beta-blockers Absence ofcorrelation between bradycardia and (1980) (0)
- THE ACTION OF MORPHINE, PETHIDINE, AND AMIDONE UPON THE INTESTINAL MOTILITY OF CONSCIOUS DOGS (2006) (0)
- Proceedings of the physiological society [proceedings]. (1977) (0)
- [Importance of experimental studies on anti-arrhythmia agents and their clinical use]. (1978) (0)
- RABBIT ATRIA INTERPRETED FROM INTRACELLULAR POTENTIAL RECORDS (2006) (0)
- [Advances in the knowledge of new anti-dysrhythmic drugs]. (1973) (0)
- The Scientific Basis for the Use of Drugs in Cardiovascular Disease (1969) (0)
- Proceedings: Possible explanation for protective action of long-term beta-adrenoceptor blockade after myocardial infarction. (1976) (0)
- Studies on the mode of action of cardioactive drugs in animals and man (1982) (0)
- Emotional Expressions in ttention-Deficit / Hyperactivity Disorder : Evidence or a Neural Marker and Stimulant Effects (2008) (0)
- [beta receptors. Contrast between the acute and prolonged effects of beta blockers]. (1978) (0)
- Cardiac Electrophysiological Effects of Selective Adrenoceptor Stimulation and Their Possible Roles in Arrhythmias (1985) (0)
- 35 Mode of action of antifibrillatory drugs (1961) (0)
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